SUMITA Yoshinori 住田吉慶

Researcher Number	50456654
Other IDs	https://orcid.org/0000-0002-1247-9763
Affiliation (Current)	2023: 長崎大学, 医歯薬学総合研究科(歯学系), 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 長崎大学, 医歯薬学総合研究科(歯学系), 教授 2014 – 2022: 長崎大学, 医歯薬学総合研究科(歯学系), 准教授 2015: 長崎大学, 医歯薬学総合研究科, 准教授 2011 – 2015: 長崎大学, 医歯(薬)学総合研究科, 准教授 2014: 長崎大学, 大学院医歯薬学総合研究科(歯学系), 准教授 … More 2012: 長崎大学, 医歯薬総合研究科, 准教授 2012: 長崎大学, 大学院・医歯薬学総合研究科, 准教授 2010 – 2011: 長崎大学, 医歯(薬)学総合研究科, 助教 2010 – 2011: 長崎大学, 大学院・医歯薬学総合研究科, 助教 2010: 長崎大学, 歯学研究科, 助教 Less
Review Section/Research Field	Principal Investigator Surgical dentistry / Dental engineering/Regenerative dentistry / Basic Section 57040:Regenerative dentistry and dental engineering-related / Medium-sized Section 57:Oral science and related fields Except Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related / Basic Section 57050:Prosthodontics-related / Medium-sized Section 57:Oral science and related fields / Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 90120:Biomaterials-related / Oral Science and related fields / Dental engineering/Regenerative dentistry / Prosthetic dentistry
Keywords	Principal Investigator 骨再生 / 細胞治療 / 再生医学 / 間葉系幹細胞 / 唾液腺 / 唾液腺再生 / リプログラム / 組織マクロファージ / 慢性免疫不全 / デザイナー細胞 … More / iPS細胞 / 巨核球 / 骨 / 分化 / エクソソーム / 遺伝子活性化基質 / 骨分化 / 幹細胞 / 臍帯 / 骨芽細胞分化 / 生体材料 / 遺伝子 / 同種細胞移植 / miRNA / microRNA / 萎縮唾液腺 / 再生 / 唾液腺萎縮 / 相互作用 / 神経堤細胞 / 幹細胞源 / 神経堤 / 幹細胞原 / 神経 / 浮遊培養 / 初期化 / 口腔組織幹細胞 … More Except Principal Investigator 骨再生 / 細胞治療 / マクロファージ / 薬剤関連顎骨壊死 / 幹細胞 / 唾液腺 / 再生医療 / ビスホスホネート製剤 / BRONJ / デノスマブ / ビスフォスフォネート製剤 / microRNA / 臍帯由来間葉系幹細胞 / 再生医学 / BMP / 遺伝子活性化基質 / 間葉系幹細胞 / インプラント周囲炎 / E-MNC / 放射線性顎骨壊死 / 臍帯MSC / 細胞移植 / インプラント / デンタルインプラント / エクソソーム / 動物モデル / 病因 / miRNA / 骨髄間質細胞 / 放射線障害 / 口腔粘膜炎 / 遺伝子導入 / 組織工学 / 再生 / 歯槽骨再生 / 骨配向性 / 慢性疾患 / 難治性疾患 / Osteomacs / ステロイド含漱 / 遺伝子送達 / 核酸医薬 / シェーグレン症候群 / 組織配向化 / 難治性硬軟組織疾患 / LPS / 細胞医薬 / 免疫細胞 / 病的老化 / 組織再生 / 1細胞解析 / 臍帯 / 骨芽細胞分化 / 自己組織化デバイス / 基質 / 遺伝子送達デバイス / 遺伝子導入担体 / 遺伝子治療 / 人工骨基質 / ベクター / 遺伝子 / 多機能細胞 / 骨シンチ / マイクロCT / 高機能細胞(E-MNC) / CD34陽性細胞 / CD34 / 線維化 / 放射線性唾液腺萎縮症 / アクチン重合 / シングルセル解析 / 細胞系譜追跡 / 骨格幹細胞 / 薬剤感受性試験 / 自発的スフェロイド / 決定論的横置換法 / 血中循環がん細胞 / マイクロ流体デバイス / 免疫病理 / 創傷治癒 / 分子標的治療法 / ロモソズマブ / 分子標的治療 / リンパ管 / 治癒関連分子 / 病因関連分子 / 細胞療法 / DRONJ / 薬剤関連顎骨壊死（MRONJ） / 血管新生抑制薬 / 抗RANKL抗体製剤 / バイオマテリアル / 口腔外科 / 骨再生医療 / ウィルスベクター / Gene Activated Matrix / Tissue engineering / 骨再生療法 / ステロイド / QQ-MNC / インプラント治療 / 骨 / 歯学 / 免疫 / 破骨細胞 / 骨芽細胞 / サイトカイン / アポトーシス / 細胞死 / 生体アパタイト結晶・コラーゲン線維複合体 / 配向性 / コラーゲン線維 / 生体アパタイト結晶 / マイクロアレイ / 骨細胞 / 骨質 / コラーゲン / オートファジー / 骨関連細胞 / 荷重 / エキソソーム / 人工骨 / 脂肪組織由来幹細胞 / 抗RANKL抗体 / 顎骨壊死 / 抗癌剤 / 抗RANKL抗体製剤関連顎骨壊死 / ビスフォスフォネート製剤関連顎骨壊死 / 治療法 / 非培養SVF細胞 / 骨吸収抑制薬関連顎骨壊死 / 脂肪由来細胞 / 口腔乾燥症 / 骨髄単核球細胞 / リプログラム / ダイレクトリプログラム / 脂肪細胞 / 分化転換 / 放射線 / 口腔癌 / 唾液腺萎縮 / 骨髄由来細胞 / 歯肉幹細胞 / Runx II / プラスミド遺伝子導入 / 即時移植 / 脂肪由来間葉系幹細胞 / 幹細胞移植 / RunxII / 骨組織再生 / リン酸カルシウム / サケコラーゲン / 脂肪由来幹細胞 / BMP4 / 口腔顎顔面再健外科学 / ディファレンシャルディスプレイ / DNAマイクロアレイ / 遺伝子解析 / 細胞培養 / 口腔外科学一般 / 骨増生 Less

Pathophysiology determination of peri-implantitis based on macrophage hierarchy and regulation of tissue alignment
- Principal Investigator
  
  澤瀬隆
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Nagasaki University
自己免疫疾患における所属リンパ節の免疫機能是正を標的軸としたデザイナー細胞の開発
- Principal Investigator
  
  井隆司
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
新規miRNA阻害型アンチセンス核酸を搭載した骨誘導性遺伝子活性化基質の開発
- Principal Investigator
  
  朝比奈泉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Nagasaki University
ステロイド含漱剤の口腔粘膜炎発症予防に関する多機関共同第Ⅲ相ランダム化比較試験
- Principal Investigator
  
  五月女さき子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Development of the are treatment strategy for ORN of the jaw with Exosome derived from E-MNC
- Principal Investigator
  
  大場誠悟
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Determination of chronic or intractable mechanisms induced by low bone quality with osteomacs and bone marrow derived stem cells interaction
- Principal Investigator
  
  黒嶋伸一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nagasaki University
組織マクロファージの動的恒常性維持機能を標的軸としたデザイナー細胞医薬の開発Principal Investigator
- Principal Investigator
  
  住田吉慶
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Nagasaki University
Understanding of pathophysiology and establishment of new treatment strategy by determining the hierarchy of macrophages in medication-related osteonecrosis of the jaw
- Principal Investigator
  
  黒嶋伸一郎
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Nagasaki University
病的老化組織からの組織再生を制御するデザイナー細胞医薬の創出
- Principal Investigator
  
  朝比奈泉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nagasaki University
多階層シングルセル解析を応用した骨再生機構の解明と新規再生療法の基盤構築
- Principal Investigator
  
  松下祐樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Nagasaki University
iPS細胞由来巨核球を骨誘導のデザイナー細胞として応用した新しい骨再生治療開発Principal Investigator
- Principal Investigator
  
  住田吉慶
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nagasaki University
Clarification of and treatment strategy for intractable soft and hard tissue diseases based on control of macrophage polarization
- Principal Investigator
  
  中島和慶
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Nagasaki University
Development of a microfluidic device for the extraction of circulating tumor cell cluster
- Principal Investigator
  
  各務秀明
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Matsumoto Dental University
アクチン動態に基づく臍帯由来間葉系幹細胞における骨芽細胞分化誘導法
- Principal Investigator
  
  IWATAKE Mayumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Nagasaki University
Development of therapeutic agent for radiation salivary gland atrophy targeting the mechanism of differentiation of tissue-resident CD34-positive cells
- Principal Investigator
  
  井隆司
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
高機能細胞治療薬E-MNCを用いた放射線性顎骨壊死の治療法の確立
- Principal Investigator
  
  大場誠悟
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Development of treatment strategies for implant induced BRONJ in rats
- Principal Investigator
  
  NAKAJIMA Kazunori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Nagasaki University
The creation of bone regenerative therapy by gene activated matrix with viruses vector
- Principal Investigator
  
  Miura Kei-ichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tohoku University
  Nagasaki University
Molecular targeted therapy for MRONJ
- Principal Investigator
  
  KUROSHIMA Shinichiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Nagasaki University
Autophagy-induced bone quality via oteocytes
- Principal Investigator
  
  SAWASE Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Oral Science and related fields
- Research Institution
  Nagasaki University
Gene activated-matrix comprised of self-assemble and multi-functional nano-devise facilitates the bone engineering
- Principal Investigator
  
  Asahina Izumi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Development of new bone regeneration method by collagen gel culture using umbilical cord MSC
- Principal Investigator
  
  IWATAKE Mayumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Functional analysis of osteoblastic cell or immature MSC derived exosomes for bone regenerationPrincipal Investigator
- Principal Investigator
  
  SUMITA Yoshinori
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Nagasaki University
Development of gene-activated matrix with MSC-exosome for bone engineering
- Principal Investigator
  
  ASAHINA Izumi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Fundamental research on the development of next generation bone tissue engineering
- Principal Investigator
  
  Kagami Hideaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Matsumoto Dental University
Transplantation effect of ADSC and SVF cells on ARONJ-like lesions in mice
- Principal Investigator
  
  KUROSHIMA Shinichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Direct conversion of umbilical mesenchymal stem cells facilitates the bone regenerationPrincipal Investigator
- Principal Investigator
  
  SUMITA Yoshinori
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Functional miRNA promotes the bone regeneration with rhBMP2 and ADCs
- Principal Investigator
  
  TAJIMA Nobutaka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Bone engineering with gene activated-matrix and non-cultured adipose cells
- Principal Investigator
  
  ASAHINA Izumi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
The investigation on salivary gland regeneration mechanisms with cell transplantation and the development of salivary gland organ regeneration
- Principal Investigator
  
  Kagami Hideaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Matsumoto Dental University
Delivery of functional microRNA accelerates the bone regeneration with BMP2 and BMAC.
- Principal Investigator
  
  ASAHINA Izumi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Delivery of bone-marrow stem cells and functional microRNA for atrophic salivary gland regenerationPrincipal Investigator
- Principal Investigator
  
  SUMITA Yoshinori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Development of cell therapy for the salivary gland tissue regeneration with direct reprogrammed dental mesenchymal cellsPrincipal Investigator
- Principal Investigator
  
  SUMITA Yoshinori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Development of stem cell therapy for the oral tissues damaged by chemo-radiation therapy
- Principal Investigator
  
  ASAHINA Izumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Alveolar bone engineering using alveolar bone marrow derived mesenchymal stem cells
- Principal Investigator
  
  NISHIMURA Masahiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Prosthetic dentistry
- Research Institution
  Nagasaki University
Tooth-derived mesenchymal cells as a cell replacement source in the treatment of neurologicalPrincipal Investigator
- Principal Investigator
  
  SUMITA Yoshinori
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Nagasaki University
Establishment of salivary gland stem cell isolation, culture, and storage for the regeneration of salivary gland
- Principal Investigator
  
  KAGAMI Hideaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Matsumoto Dental University
  The University of Tokyo
Jaw bone regeneration using gene activated matrix incorporated withdirectly prepared adipose derived stem cells
- Principal Investigator
  
  ASAHINA Izumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Selection of osteogenic progenitor cells in gingival tissue
- Principal Investigator
  
  NISHIMURA Masahiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Nagasaki University

[Book] New Trends in Tissue Engineering and Regenerative Medicine - Official Book of the Japanese Society for Regenerative Medicine"2014
- Author(s)
  Sumita Y, Asahina I, Tran SD, Agata H, Inoue M, Tojo A, Kagami H
- Total Pages
  14
- Publisher
  Intech
- Data Source
  KAKENHI-PROJECT-25293416
[Book] 歯・歯槽骨(歯槽骨の再生医療/歯の再生医療), 第2節; 臓器・器官ごとの再生医療研究の動向, 再生医療における臨床研究と製品開発～医工連携に向けた「自社技術」と「再生医療」の接点を探る～2013
- Author(s)
  住田吉慶, 朝比奈泉
- Total Pages
  9
- Publisher
  情報技術協会
- Data Source
  KAKENHI-PROJECT-22390375
[Book] 再生医療における臨床研究と製品開発2013
- Author(s)
  住田吉慶、朝比奈泉
- Total Pages
  8
- Publisher
  情報技術協会
- Data Source
  KAKENHI-PROJECT-22390375
[Book] 再生医療叢書第8 巻歯学系2012
- Author(s)
  住田吉慶、朝比奈泉、各務秀明
- Publisher
  唾液腺の再生
- Data Source
  KAKENHI-PROJECT-23659951
[Book] 再生医療叢書2012
- Author(s)
  住田吉慶、朝比奈泉、各務秀明
- Publisher
  唾液腺の再生
- Data Source
  KAKENHI-PROJECT-23659952
[Book] TherapeuticApplications in Disease and Injury, Volume2, Springer2011
- Author(s)
  Kagami H, Agata H, Sumita Y, Tojo A. Heterogeneous responses of human bone marrow stromal cells multipotent mesenchyme stromal cells to osteogenic induction.
- Publisher
  Ed. Hayat MA, Stem Cells and Cancer Stem Cells
- Data Source
  KAKENHI-PROJECT-22390381
[Journal Article] Gene-Activated Matrix with Self-Assembly Anionic Nano-Device Containing Plasmid DNAs for Rat Cranial Bone Augmentation2021
- Author(s)
  Masahito Hara,Yoshinori Sumita,Yukinobu Kodama,Mayumi Iwatake, Hideyuki Yamamoto,Rena Shido,Shun Narahara,Takunori Ogaeri,Hitoshi Sasaki and Izumi Asahina
- Journal Title
  
  Materials
  
  Volume: 14 Issue: 22 Pages: 22-22
- DOI
  10.3390/ma14227097
- NAID
  120007186847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23059, KAKENHI-PROJECT-17H01604, KAKENHI-PROJECT-20K10010
[Journal Article] Gene-activated matrix harboring a miR20a-expressing plasmid promotes rat cranial bone augmentation2021
- Author(s)
  Shido Rena、Sumita Yoshinori、Hara Masahito、Iwatake Mayumi、Narahara Shun、Umebayashi Mayumi、Miura Kei-ichiro、Kodama Yukinobu、Asahina Izumi
- Journal Title
  
  Regenerative Biomaterials
  
  Volume: 8 Issue: 2 Pages: 1-9
- DOI
  10.1093/rb/rbaa060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10010, KAKENHI-PROJECT-17H01604
[Journal Article] Resident CD34-positive cells contribute to peri-endothelial cells and vascular morphogenesis in salivary gland after irradiation2020
- Author(s)
  Takashi I, Yuichiro Ueda, Philipp Woersdoerfer, Yoshinori Sumita, Izumi Asahina, Sueleyman Erguen
- Journal Title
  
  Journal of Neural Transmission
  
  Volume: 127 Issue: 11 Pages: 1467-1479
- DOI
  10.1007/s00702-020-02256-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10142
[Journal Article] A stable protocol for the fabrication of transplantable human oral mucosal epithelial cell sheets for clinical application.2020
- Author(s)
  Kasai Y, Takagi R, Kobayashi S, Owaki T, Yamaguchi N, Fukuda H, Sakai Y, Sumita Y, Kanai N, Isomoto H, Kanetaka K, Ohki T, Asahina I, Nagai K, Nakao K, Takeda N, Okano T, Eguchi S, Yamato M.
- Journal Title
  
  Regen Ther.
  
  Volume: 14 Pages: 87-94
- DOI
  10.1016/j.reth.2019.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09664, KAKENHI-PROJECT-18H02994
[Journal Article] Phase 1 clinical study of cell therapy with effective-mononuclear cells (E-MNC) for radiogenic xerostomia (first-in-human study) (FIH study on E-MNC therapy for radiogenic xerostomia)2020
- Author(s)
  Sumita Y, Iwamoto N, Seki M, Yoshida T, Honma R, Iwatake M, Ohba S, Takashi I, Hotokezaka Y, Harada H, Kuroshima S, Nagai K, Asahara T, Atsushi Kawakam I, Asahina I
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 99 Issue: 26 Pages: e20788-e20788
- DOI
  10.1097/md.0000000000020788
- NAID
  120006988135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02994, KAKENHI-PROJECT-18K08411, KAKENHI-PROJECT-18K09664
[Journal Article] Alveolar bone preservation by a hydroxyapatite/collagen composite material after tooth extraction.2019
- Author(s)
  Ohba S, Sumita Y, Nakatani Y, Noda S, Asahina I.
- Journal Title
  
  Clin Oral Investig
  
  Volume: 23 Issue: 5 Pages: 2413-2419
- DOI
  10.1007/s00784-018-2705-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05546, KAKENHI-PROJECT-18H02994
[Journal Article] First clinical application of octacalcium phosphate collagen composite on bone regeneration in maxillary sinus floor augmentation: a prospective, single-arm, open-label clinical trial2019
- Author(s)
  Miura K, Sumita Y, Kajii F, Tanaka H, Kamakura S, Asahina I
- Journal Title
  
  Journal of Biomedical Materials Research Part B: Applied Biomaterials
  
  Volume: in press Issue: 1 Pages: 243-252
- DOI
  10.1002/jbm.b.34384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03159, KAKENHI-PROJECT-16H05546, KAKENHI-PROJECT-18K19891
[Journal Article] Systemic administration of quality- and quantity-controlled PBMNCs reduces bisphosphonate-related osteonecrosis of the jaw-like lesions in mice2019
- Author(s)
  Kuroshima S, Nakajima K, Sasaki M, Takashi I, Y Sumita, Asahara T, Asahina I, Sawase T
- Journal Title
  
  Stem Cell Res Ther.
  
  Volume: 10 Issue: 1 Pages: 209-209
- DOI
  10.1186/s13287-019-1308-8
- NAID
  120006988442
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09664, KAKENHI-PROJECT-19K08525, KAKENHI-PROJECT-18H02994
[Journal Article] Intra-Bone Marrow Administration of Mesenchymal Stem/Stromal Cells Is a Promising Approach for Treating Osteoporosis.2019
- Author(s)
  Agata H, Sumita Y, Hidaka T, Iwatake M, Kagami H, Asahina I.
- Journal Title
  
  Stem Cells Int
  
  Volume: 2019 Pages: 4214281-4214281
- DOI
  10.1155/2019/4214281
- NAID
  120006988353
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09664
[Journal Article] Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands.2019
- Author(s)
  I T, Sumita Y, Yoshida T, Honma R, Iwatake M, Raudales JLM, Shizuno T, Kuroshima S, Masuda H, Seki M, Tran SD, Asahara T, Asahina I.
- Journal Title
  
  Stem Cell Res Ther.
  
  Volume: 10 Issue: 1 Pages: 304-304
- DOI
  10.1186/s13287-019-1414-7
- NAID
  120006988389
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09664, KAKENHI-PROJECT-19K08525, KAKENHI-PROJECT-18H02994, KAKENHI-PROJECT-18K17229
[Journal Article] Clinical application of autogenous partially demineralized dentin matrix prepared immediately after extraction for alveolar bone regeneration in implant dentistry: a pilot study.2018
- Author(s)
  Minamizato T, Koga T, I T, Nakatani Y, Umebayashi M, Sumita Y, Ikeda T, Asahina I.
- Journal Title
  
  Int J Oral Maxillofac Surg
  
  Volume: 47 Issue: 1 Pages: 125-132
- DOI
  10.1016/j.ijom.2017.02.1279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05546
[Journal Article] Bone marrow concentrate promotes bone regeneration with a suboptimal-dose of rhBMP-22018
- Author(s)
  Egashira Kazuhiro、Sumita Yoshinori、Zhong Weijian、I Takashi、Ohba Seigo、Nagai Kazuhiro、Asahina Izumi
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 1 Pages: e0191099-e0191099
- DOI
  10.1371/journal.pone.0191099
- NAID
  120006988082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05044, KAKENHI-PROJECT-18K09664, KAKENHI-PROJECT-16H05546, KAKENHI-PROJECT-18H02994
[Journal Article] 難治性口腔疾患を対象とした再生医療2017
- Author(s)
  住田吉慶
- Journal Title
  
  長崎県歯科医師会学術誌
  
  Volume: 2 Pages: 37-41
- Data Source
  KAKENHI-PROJECT-15H05044
[Journal Article] Gene-activated matrix comprised of atelocollagen and plasmid DNA encoding bmp4 or runx2 promotes rat cranial bone augmentation2015
- Author(s)
  Umebayashi M, Sumita Y, Kawai Y, Watanabe S, Asahina I
- Journal Title
  
  BioResearch Open Access
  
  Volume: 4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670863
[Journal Article] Transient exposure to hypoxic and anoxic oxygen concentrations promotes either osteogenic or ligamentogenic characteristics of PDL cells.2015
- Author(s)
  Kawasaki T, Sumita Y, Egashira K, Ohba S, Kagami H, Tran SD, Asahina I.
- Journal Title
  
  Biores Open Access
  
  Volume: 4 Issue: 1 Pages: 175-187
- DOI
  10.1089/biores.2014.0049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293416
[Journal Article] Gene-activated matrix comprised of atelocollagen and plasmid DNA encoding Bmp4 or Runx2 ｐromotes rat cranial bone augmentation2015
- Author(s)
  Umebayashi M, Sumita Y, Kawaki Y, Watanabe S, Asahina I
- Journal Title
  
  BioResearch Open Access
  
  Volume: ４
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293413
[Journal Article] Bone marrow-derived cell therapy for oral mucosal repair after irradiation2014
- Author(s)
  I T, Sumita Y, Minamizato T, Umebayashi M, Tran SD, Asahina I
- Journal Title
  
  J Dent Res
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375
[Journal Article] Bone Marrow-derived Cell Therapy for Oral Mucosal Repair after Irradiation2014
- Author(s)
  I T, Sumita Y, Minamizato T, Umebayashi M, Liu Y, Tran SD, Asahina I
- Journal Title
  
  Journal of Dental Research
  
  Volume: 30 Pages: 813-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670864
[Journal Article] Treating salivary gland hypofunction at both intial and advanced stages of sjogren's-like disease : a comparative study of bone marrow- versus spleen-cell therapy with a one-year monitoring period2014
- Author(s)
  Khalili S, Faustman DL, Liu Y, Sumita Y, Blank D, Peterson A, Kodama S, Tran SD
- Journal Title
  
  Cytotherapy
  
  Volume: vol.16(3) Issue: 3 Pages: 412-23
- DOI
  10.1016/j.jcyt.2013.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375
[Journal Article] Treatment for salivary gland hypofunction at both initial and advanced stages of Sjogren-like disease: a comparative study of bone marrow therapy versus spleen cell therapy with a 1-year monitoring period.2014
- Author(s)
  Khalili S, Faustman DL, Liu Y, Sumita Y, Blank D, Peterson A, Kodama S, Tran SD.
- Journal Title
  
  Cytotherapy
  
  Volume: 16(3) Pages: 412-423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670864
[Journal Article] Ischemic culture of dental pulp-derived cells is a useful model in which to investigate mechanisms of post-ischemic tissue recovery2013
- Author(s)
  Agata H, Sumita Y, Asahina I, Tojo A, Kagami H
- Journal Title
  
  Histol Histopathol
- Data Source
  KAKENHI-PROJECT-23659951
[Journal Article] Ischemic culture of dental pulp-derived cells is a useful model in which to investigate mechanisms of post-ischemic tissue recovery.2013
- Author(s)
  Agata A, Sumita Y, Asahina I, Tojo A, Kagami A,
- Journal Title
  
  Histol Histopathol.
  
  Volume: 28 Pages: 985-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293416
[Journal Article] GDFs promote tenogenic characteristics on human periodontal ligament-derived cells in culture at late passages2013
- Author(s)
  Xia D, Sumita Y, Liu Y, Tai Y, Wang J, Uehara M, Agata H, Kagami H, Fan Z, Asahina I, Wang S, Tran SD
- Journal Title
  
  Growth Factors
  
  Volume: vol.31(5) Issue: 5 Pages: 165-73
- DOI
  10.3109/08977194.2013.830611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-23689078, KAKENHI-PROJECT-25293416, KAKENHI-PROJECT-25670837
[Journal Article] Ischemic culture of dental pulp-derived cells is a useful model in which to investigate mechanisms of post-ischemic tissue recovery2013
- Author(s)
  Agata H, Sumita Y, Asahina I, Tojo A, Kagami H
- Journal Title
  
  Histol Histopathol
  
  Volume: vol.28(8) Pages: 985-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375
[Journal Article] Ischemic culture of dental pulp-derived cells is a useful model in which to investigate mechanisms of post-ischemic tissue recovery.2013
- Author(s)
  Agata H, Sumita Y, Asahina I, Tojo A, Kagami H.
- Journal Title
  
  Histology and l Histopathology
  
  Volume: 28(8) Pages: 985-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375
[Journal Article] Effect of platelet-rich plasma on the bone engineering with the alloplastic substitute containing BMP22013
- Author(s)
  Yoshida K, Sumita Y, Marukawa E, Harashima M, Asahina I
- Journal Title
  
  Biomed Mater Eng
  
  Volume: vol.23(3) Issue: 3 Pages: 163-72
- DOI
  10.3233/bme-130741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-25670863
[Journal Article] In vivo comparison of the bone regeneration capability of human bone marrow concentrates vs. platelet-rich plasma2012
- Author(s)
  Zhong W, Sumita Y, Ohba S, Kawasaki T, Nagai K, Ma G, Asahina I.
- Journal Title
  
  PLoS One
  
  Volume: 7(7)
- NAID
  120006985697
- Data Source
  KAKENHI-PROJECT-22390387
[Journal Article] In vivocomparison of the bone regeneration capability of human bone marrow concentrate vs. platelet-rich plasma2012
- Author(s)
  Zhong W, Sumita Y, Ohba S, Kawasaki T, Nagai K, Ma G, Asahina I
- Journal Title
  
  PLoS One
  
  Volume: vol.7(7)
- NAID
  120006985697
- Data Source
  KAKENHI-PROJECT-23659952
[Journal Article] Ueda M. Effect of GDF-5 and BMP-2 on the expression of tendo/ligamentogenesis-related markers in human PDL-derived cells2012
- Author(s)
  Inoue M, Ebisawa K, Itaya T, Sugito T, Ymawaki A, Sumita Y, Narita Y, Agata H, Kagami H
- Journal Title
  
  Oral Dis
  
  Volume: vol.18(2) Pages: 206-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375
[Journal Article] Characteristic difference in the composition of osteogenic cell populations of BMSCs isolated from untreated, hemolysed, or Ficoll-treated rat bone marrow2012
- Author(s)
  Agata H, Yamazaki M, Uehara M, Hori A, Sumita Y, Tojo A, Kagami H
- Journal Title
  
  Cytotherapy
  
  Volume: vol.14(7) Issue: 7 Pages: 791-801
- DOI
  10.3109/14653249.2012.674639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390381, KAKENHI-PROJECT-23591373, KAKENHI-PROJECT-23659912
[Journal Article] Formation of engineered bone with adipose stromal cells from buccal fat pad2012
- Author(s)
  Shiraishi T, Sumita Y, Wakamatsu Y, Nagai K, Asahina I
- Journal Title
  
  J Dent Res
  
  Volume: vol.91(6) Issue: 6 Pages: 592-599
- DOI
  10.1177/0022034512445633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390387
[Journal Article] Formation of engineered bone with adipose stromal cells from buccal fat pad2012
- Author(s)
  Shiraishi T, Sumita Y, Wakamastu Y, Nagai K, Asahina I.
- Journal Title
  
  J Dent Res
  
  Volume: 91(6) Pages: 592-7
- Data Source
  KAKENHI-PROJECT-22390387
[Journal Article] Effect of GDF-5 and BMP-2 on the expression of tendo/ligamentogenesis-related markers in human PDL-derived cells2012
- Author(s)
  Inoue M
- Journal Title
  
  Oral disease
  
  Volume: 18 Issue: 2 Pages: 206-212
- DOI
  10.1111/j.1601-0825.2011.01871.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390381
[Journal Article] Reconstruction of the mandible bone by treatment of resected bone with pasteurization -Long-term follow-up-2012
- Author(s)
  Uehara M, Inokuchi T, Sano K, Sumita Y, Asahina I
- Journal Title
  
  J Craniofac Surg
  
  Volume: vol.23(6) Issue: 6 Pages: 1773-5
- DOI
  10.1097/scs.0b013e318266fd4c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375
[Journal Article] In vivo comparison of the bone regeneration capability of human bone marrow concentrate vs. platelet-rich plasma2012
- Author(s)
  Zhong W, Sumita Y, Ohba S, Kawasaki T, Nagai K, Ma G, Asahina I
- Journal Title
  
  PLoS One
  
  Volume: vol.7(7) Issue: 7 Pages: e40833-e40833
- DOI
  10.1371/journal.pone.0040833
- NAID
  120006985697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390387
[Journal Article] Predictive factor for photodynamic therapy effects on oral squamous cell carcinoma and oral epithelial dysplasia2011
- Author(s)
  Uehara M, Ikeda H, Nonaka M, Sumita Y, Nanashima A, Nonaka T, Asahina I
- Journal Title
  
  Arch Oral Biol
  
  Volume: vol.56(11) Pages: 1366-1372
- Data Source
  KAKENHI-PROJECT-23659952
[Journal Article] Bone Marrow Derived Cells: a potential approach for the treatment of xerostomia2011
- Author(s)
  Tran SD, Sumita Y, Khalili S
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: vol.43(1) Pages: 5-9
- Data Source
  KAKENHI-PROJECT-23659951
[Journal Article] Marrow Derived Cells: a potential approach for the treatment of xerostomia2011
- Author(s)
  Tran SD, Sumita Y, Khalili S. Bone
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: vol.43(1) Pages: 5-9
- Data Source
  KAKENHI-PROJECT-23659952
[Journal Article] Bone marrow-derived cells rescue salivary gland function in mice with head and neck irradiation2011
- Author(s)
  Sumita Y, Liu Y, Khalili S, Maria OM, Xia D, Key S, Cotrim AP, Mezey E, Tran SD
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: vol.43(1) Pages: 80-87
- Data Source
  KAKENHI-PROJECT-23659951
[Journal Article] Predictive factor for photodynamic therapy effects on oral squamous cell carcinoma and oral epithelial dysplasia2011
- Author(s)
  Uehara M, Nanashima A, ら
- Journal Title
  
  Arch Oral Biol
  
  Volume: 56 Issue: 11 Pages: 1366-1372
- DOI
  10.1016/j.archoralbio.2011.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591777, KAKENHI-PROJECT-22390375
[Journal Article] Bone Marrow Derived Cells : a potential approach for the treatment of xerostomia2011
- Author(s)
  Tran SD, Sumita Y, Khalili S
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: vol.43(1) Issue: 1 Pages: 5-9
- DOI
  10.1016/j.biocel.2010.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390381
[Journal Article] Engineering bone formation from human dental pulp- and periodontal ligament-derived cells2011
- Author(s)
  Ikeda H, 他
- Journal Title
  
  Ann Biomed Eng
  
  Volume: 39 Issue: 1 Pages: 26-34
- DOI
  10.1007/s10439-010-0115-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390496, KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22592086
[Journal Article] Engineering Bone Formation from Human Dental Pulp- and Periodontal Ligament-Derived Cells2011
- Author(s)
  Ikeda H, Sumita Y, Ikeda M, Ikeda H, Okumura T, Sakai E, Nishimura M., Asahina I
- Journal Title
  
  Ann Biomed Eng
  
  Volume: 39(1) Pages: 26-34
- NAID
  120006984446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390387
[Journal Article] Bone marrow-derived cells rescue salivary gland function in mice with head and neck irradiation2011
- Author(s)
  Sumita Y, Liu Y, Khalili S, Maria OM, Xia D, Key S, Cotrim AP, Mezey E, Tran SD
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: vol.43(1) Pages: 80-87
- Data Source
  KAKENHI-PROJECT-23659952
[Journal Article] Bone marrow-derived cells rescue salivary gland function in mice with head and neck irradiation2011
- Author(s)
  Sumita Y, Liu Y, Khalili S, Maria OM, Xia D, Key S, Cotrim AP, Mezey E, Tran SD
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: vol.43(1) Issue: 1 Pages: 80-87
- DOI
  10.1016/j.biocel.2010.09.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390381
[Journal Article] Microchimerism in salivary glands after blood- and marrow-derived stem cell transplantation2011
- Author(s)
  Tran SD, Redman RS, Barrett AJ, Pavletic SZ, Key S, Liu Y, Carpenter A, Nguyen HM, Sumita Y, Baum BJ, Pillemer SR, Mezey E
- Journal Title
  
  Biol Blood Marrow Transplant
  
  Volume: vol.17(3) Issue: 3 Pages: 429-433
- DOI
  10.1016/j.bbmt.2010.09.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390381
[Journal Article] Differential effects of growth/ differentiation factor-5 on the porcine dental papilla- and follicle-derived cells2010
- Author(s)
  Sumita Y, Kagami H, Honda MJ, Ueda M.
- Journal Title
  
  Growth Factors
  
  Volume: vol.28 Issue: 1 Pages: 56-65
- DOI
  10.3109/08977190903373380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390381, KAKENHI-PROJECT-23659912
[Journal Article] Bone marrow cells are a source of undifferentiated cells to prevent Sjogren's syndrome and to preserve salivary glands function in the non-obese diabetic mice2010
- Author(s)
  Khalili S, Liu Y, Sumita Y, Maria OM, Blank D, Key S, Mezey E, Tran SD
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: vol.42(11) Issue: 11 Pages: 1893-1899
- DOI
  10.1016/j.biocel.2010.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390381
[Journal Article] Differential effect of scaffold shape on dentin regeneration2010
- Author(s)
  Tonomura A, Mizuno D, Hisada A, Kuno N, Ando Y, Sumita Y, Honda MJ, Satomura K, Sakurai H, Ueda M, Kagami H
- Journal Title
  
  Ann Biomed Eng
  
  Volume: vol.38 Issue: 4 Pages: 1664-1671
- DOI
  10.1007/s10439-010-9910-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390375, KAKENHI-PROJECT-22390381, KAKENHI-PROJECT-23659912
[Journal Article] Ischemic culture of dental pulp-derived cells is a useful model in which to investigate mechanisms of post-ischemic tissue recovery.
- Author(s)
  Agata A, Sumita Y, Asahina I, Tojo A, Kagami H
- Journal Title
  
  Histol Histopathol
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/23629696.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390381
[Patent] ヒト臍帯由来間葉系幹細胞から骨芽細胞の製造を目的としたアクチン重合阻害剤による分化誘導技術2020
- Inventor(s)
  住田吉慶,岩竹真弓,朝比奈　泉,小守壽文
- Industrial Property Rights Holder
  住田吉慶,岩竹真弓,朝比奈　泉,小守壽文
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-20K10010
[Patent] ヒト臍帯由来間葉系幹細胞から骨芽細胞の製造を目的としたアクチン重合阻害剤による分化誘導技術2019
- Inventor(s)
  住田吉慶、岩竹真弓、朝比奈泉、小守壽文
- Industrial Property Rights Holder
  国立大学法人　長崎大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-15H05044
[Patent] ヒト臍帯由来間葉系幹細胞から骨芽細胞の製造を目的としたアクチン重合阻害剤による分化誘導技術2018
- Inventor(s)
  住田吉慶,岩竹真弓,朝比奈　泉,小守壽文
- Industrial Property Rights Holder
  住田吉慶,岩竹真弓,朝比奈　泉,小守壽文
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-006969
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K11847
[Patent] 特許件2018
- Inventor(s)
  住田吉慶、岩竹真弓、朝比奈泉、小守壽文
- Industrial Property Rights Holder
  国立法人長崎大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K11847
[Presentation] DAMPs排除機能を備えたEffectively Mononuclear Cell（E-MNC）は放射線性萎縮唾液腺の再生を促進する2022
- Author(s)
  井隆司, 本間遼, 魚返拓利, 関誠, 朝比奈泉, 住田吉慶
- Organizer
  日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K10142
[Presentation] 歯槽骨再生治療を対象とした骨誘導性遺伝子活性化基質の開発研究2022
- Author(s)
  住田吉慶
- Organizer
  第21回再生医療学会シンポジウム13 新しく開発された骨再生研究の最前線
- Invited
- Data Source
  KAKENHI-PROJECT-17H01604
[Presentation] アクチン脱重合型臍帯由来間葉系幹細胞による新規骨再生細胞治療薬の開発2020
- Author(s)
  岩竹真弓、住田吉慶、長村登紀子、朝比奈泉
- Organizer
  第19回再生医療学会
- Data Source
  KAKENHI-PROJECT-17K11847
[Presentation] Effective gene-activated matrix with self-assembly nano-devices for bone engineering.2019
- Author(s)
  Hara M, Sumita Y, Shido R, Kodama Y, Asahina I
- Organizer
  International Association for Dental Research (IADR) 97th General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01604
[Presentation] 新規自己組織化ナノデバイス (Nanoball) を応用した骨誘導性遺伝子活性化基質(GAM)の開発2019
- Author(s)
  原昌士, 住田吉慶, 四道玲奈, 楢原峻, 朝比奈泉
- Organizer
  第64回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17H01604
[Presentation] micro RNAを応用した遺伝子活性化基質（GAM）による新規人工骨基質の開発2018
- Author(s)
  四道玲奈, 住田吉慶, 原昌士, 楢原峻, 朝比奈泉
- Organizer
  第63回日本口腔外科学会総会・学術大会,
- Data Source
  KAKENHI-PROJECT-17H01604
[Presentation] QQ-MNC移植は高頻度発現型マウスBRONJ様病態を緩解させる2018
- Author(s)
  黒嶋伸一郎，佐々木宗輝，住田吉慶，朝比奈　泉，澤瀬　隆
- Organizer
  第4回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18H02994
[Presentation] Actin-depolymeraization inducing by Col-1 culture accelerates osteoblastic differentiation of human umbilical cord mesenchymal stem cells.2018
- Author(s)
  Iwatake M, Sumita Y, Nagamura T, Asahina I
- Organizer
  5th TERMIS World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11847
[Presentation] QQ-MNC移植は高頻度発現型マウスBRONJ様病態を緩解させる2018
- Author(s)
  黒嶋伸一郎，佐々木宗輝，住田吉慶，朝比奈　泉，澤瀬　隆
- Organizer
  第4回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K09664
[Presentation] Effective Peripheral Blood Mononuclear Cells Promote the Regeneration of Radiation Injured Salivary Glands2018
- Author(s)
  3.Sumita Y，Takashi I，Iwatake M，Yoshida T，Tran SD，Asahara T, Asahina I
- Organizer
  5th TERMIS World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11847
[Presentation] Actin-depolymeraization inducing by Col-1 culture accelerates osteoblastic differentiation of human umbilical cord mesenchymal stem cells2018
- Author(s)
  Ｉwatake M, Sumita Y, Nagamura T, Asahina I
- Organizer
  5the TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05044
[Presentation] Gene Activated-matrix (GAM) comprised of atelocollagen and plasmid DNA encoding microRNA promotes rat cranial bine augmentation2018
- Author(s)
  Shido R, Sumita Y, Hara M, Narahara S, Asahina I
- Organizer
  The American Society for Bone and Mineral Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01604
[Presentation] 歯槽骨の再生を目指した細胞治療開発への挑戦2018
- Author(s)
  住田吉慶
- Organizer
  第36回日本骨代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05044
[Presentation] micro RNAを応用した遺伝子活性化基質（GAM）による新規人工骨基質の開発2018
- Author(s)
  四道玲奈, 住田吉慶, 原昌士, 楢原峻, 朝比奈泉
- Organizer
  第63回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-15H05044
[Presentation] 機能性microRNAを搭載した遺伝子活性化基質（GAM）による骨再生の試み2018
- Author(s)
  4.四道玲奈, 住田吉慶, 岩竹真弓, 楢原峻, 原昌士, 坂下直美, 朝比奈泉
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17H01604
[Presentation] 臍帯由来管葉系幹細胞におけるアクチン脱重合の活性制御による新規骨再生法構築へのアプローチ2017
- Author(s)
  岩竹真弓, 住田吉慶, 長村登紀子, 朝比奈泉
- Organizer
  第32回長崎障害者支援再生医療研究会
- Data Source
  KAKENHI-PROJECT-15H05044
[Presentation] 老化と口の疾患に挑戦する再生医療　-健康長寿のために-2017
- Author(s)
  住田吉慶
- Organizer
  日本口腔インプラント学会第38回中部支部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05044
[Presentation] 機能性micro(mi)RNAを搭載した遺伝子活性化基質（GAM）による骨再生の試み2017
- Author(s)
  四道玲奈，住田吉慶，河井洋祐，楢原峻，朝比奈泉
- Organizer
  第62回(公社)日本口腔外科学会総会学術大会
- Data Source
  KAKENHI-PROJECT-15H05044
[Presentation] QQ-MNCs transplantation promotes impaired oral wound healing in mice.2017
- Author(s)
  Nakajima K, Kuroshima S, Sasaki M, I Y, Sumita Y, Asahina I, Sawase T
- Organizer
  95th General Session & Exhibition of the IADR.
- Place of Presentation
  San Francisco, Calif, USA
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11258
[Presentation] ヒト臍帯由来間葉系幹細胞による骨芽細胞分化に関するコラーゲン培養の促進効果2017
- Author(s)
  岩竹真弓、住田吉慶、長村登紀子、長村登紀子、朝比奈泉
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-15H05044
[Presentation] 血管内皮前駆細胞を主体とする培養濃縮細胞群移植によるビスフォスフォネート製剤関連抜歯窩治癒不全に対する治療効果の検証．2016
- Author(s)
  中島和慶，黒嶋伸一郎，佐々木宗輝，井　隆司，住田吉慶，朝比奈　泉，澤瀬　隆
- Organizer
  第46回公益社団法人日本口腔インプラント学会学術大会
- Place of Presentation
  名古屋国際会議場，愛知県，名古屋市
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-15K11258
[Presentation] Successful bone agumentation by the graft of plasmid DNA, BMP4 or RUNX2, embedded in atelocollagen.2015
- Author(s)
  Umebayashi M, Sumita Y, Asahina I
- Organizer
  ICOMS
- Place of Presentation
  Melbourne(Canada)
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-15H05044
[Presentation] Successful bone augmentation by the graft of plasmid DNA, BMP4 or Runx2, embedded in atelocollagen.2015
- Author(s)
  Umebayashi M,, Sumita Y, Asahina I.
- Organizer
  ICOMS
- Place of Presentation
  Melbourne（オーストラリア）
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293413
[Presentation] INFLUENCE OF ENDOTHELIAL PROGENITOR CELLS ON INTRAORAL WOUND HEALING IN MICE.2015
- Author(s)
  Nakajima K, Kuroshima S, Sasaki M, Aoki Y, Sumita Y, Takashi I, Asahina I, Masuda H, Asahina T, Sawase T.
- Organizer
  Australian New Zealand Bone & Mineral Society Annual Scientific Meeting 2015
- Place of Presentation
  Hobart, Tasmania, Australia
- Year and Date
  2015-11-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11258
[Presentation] Cell therapy for radiation-induced oral mucositis with bone marrow-derived cells.2013
- Author(s)
  I T, Sumita Y, Umebayashi M, Minamizato T, Liu Y, Tran SD, Asahina I.
- Organizer
  Gordon Research Conference-Mucosal Health & Disease-
- Place of Presentation
  Easton, MA, USA
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] 朝比奈泉歯槽骨・唾液腺の再生研究今後の展開2013
- Author(s)
  各務秀明、縣秀樹、住田吉慶
- Organizer
  第12回日本再生医療学会総会シンポジウム 5歯科における再生医療の将来
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390381
[Presentation] Cell therapy for radiation-induced oral mucositis with bone marrow-derived cells.2013
- Author(s)
  I T, Sumita Y, Minamizato T, Tobita T, Younan L, Tran SD, Asahina I.
- Organizer
  International Society for Stem Cell Reserch
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] Bone marrow aspirate concentrate promotes the bone engineering with rhBMP-2.2013
- Author(s)
  Umebayashi M, Miura K, Sumita Y, Egashira K, Kazuhiro N,Weijian Z, Aasahina I.
- Organizer
  International Society for Stem Cell Reserch
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] 虚血環境モデルとしての重度低酸素培養条件がヒト歯根膜由来細胞の生存, 可塑性, 分化に与える影響について2012
- Author(s)
  川崎貴子, 住田吉慶, 縣秀樹, 各務秀明, Tran SD, 朝比奈泉
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-12
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] 細胞治療による唾液腺再生療法に関する基礎的研究2012
- Author(s)
  住田吉慶
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23659952
[Presentation] Bone Regeneration Capability of Human Bone-Marrow Concentrates vs. Platelet-Rich Plasma.2012
- Author(s)
  Umebayashi M, Zhong W, Sumita Y, Ohba S, Nagai, Asahina I
- Organizer
  ISSCR
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] 細胞治療による唾液腺再生療法に関する基礎的研究2012
- Author(s)
  住田吉慶、Tran SD、各務秀明、朝比奈泉
- Organizer
  第11回再生医療学会総会シンポジウム2
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659951
[Presentation] Effect of transient hypoxic stimulation on cultured human periodontal ligament derived-cells2012
- Author(s)
  Kawasaki T, Sumita Y , Agata H, Kagami H, Taran SD, Asahina I.
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] 細胞治療による唾液腺再生療法に関する基礎的研究2012
- Author(s)
  住田吉慶
- Organizer
  第57回日本口腔外科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659951
[Presentation] 重度低酸素条件による歯根膜由来幹細胞の選択的培養の試み2011
- Author(s)
  川崎貴子、住田吉慶、朝比奈泉
- Organizer
  第56回日本口腔外科学会総会・学術大会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] 重度低酸素条件による歯根膜由来細胞の選択的培養の試み2011
- Author(s)
  川崎貴子, 住田吉慶, 縣秀樹, 各務秀明, 朝比奈泉
- Organizer
  第56回日本口腔外科学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] The differential inducibility of demineralized bone-and dentin-matrices on the regeneration of bone and dentin from human dental cells2011
- Author(s)
  Mayumi Umebayash, Yoshinori Sumita, Izumi Asahina
- Organizer
  2^<nd> International Auto-Tooth Bone Bank Symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] Bone Marrow Derived Cells: a Potential Approach for the Treatment of Xerostomia2011
- Author(s)
  Sumita Y, Khalili S, Liu Y, Mario OM, Key S, Mezey E, Tran SD
- Organizer
  第3回口腔先端応用医科学研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659951
[Presentation] one Regeneration Capability of Human Bone-Marrow Concentrates vs.Platelet-Rich Plasma2011
- Author(s)
  梅林真由美, 仲維剣, 住田吉慶, 大場誠悟, 長井一浩, 朝比奈泉
- Organizer
  第26回長崎DDS・再生医療研究会
- Place of Presentation
  長崎
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] ヒト培養歯根膜由来細胞におけるGDF5,GDF7添加刺激による腱分化能の制御2011
- Author(s)
  川崎貴子, 住田吉慶, 若松由香, 縣秀樹, 各務秀明, 朝比奈泉
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] Growth/differentiation factors (GDFs) maintain tendongenic characteristics of human periodontal ligament-derived cells in culture2011
- Author(s)
  Sumita Y, Xia D, Wakamatsu Y, Kawasaki T, Liu Y, Maria O, Khalili S, Agata H, Kagami H, Tran SD, Asahina I
- Organizer
  9th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] 重度低酸素条件による歯根膜由来細胞の選択的培養の試み2011
- Author(s)
  川崎貴子, 住田吉慶, 縣秀樹, 各務秀明, 朝比奈泉
- Organizer
  第56回日本口腔外科学会総会・学術大会
- Place of Presentation
  大阪
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] ヒト培養歯根膜由来細胞におけるGDF5, GDF7添加刺激による腱分化能の制御2011
- Author(s)
  川崎貴子, 住田吉慶, 若松由香, 縣秀樹, 各務秀明, 朝比奈泉
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] Growth/differentiation factors (GDFs) maintain tendongenic characteristics of human periodontal ligament-derived cells in culture2011
- Author(s)
  Sumita Y , Xia D, Wakamatsu Y, Kawasaki T, Liu Y, Maria OM, Khalili S, Agata H, Kagami H, Tran SD, Asahina I.
- Organizer
  9th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Toronto, Canada
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22390375
[Presentation] ヒト頬脂肪体由来幹細胞(ADSCs)を用いた骨再生2011
- Author(s)
  白石剛士, 池田秀吉, 住田吉慶, 大場誠悟, 若松由香, 長井一浩, 朝比奈泉
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] ヒト頬脂肪体由来幹細胞(ADSCs)を用いた骨再生2010
- Author(s)
  白石剛士, 住田吉慶, 池田秀吉, 大場誠悟, 朝比奈泉
- Organizer
  日本口腔科学会学術集会
- Place of Presentation
  札幌(札幌プリンスホテル)
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] Bone regeneration using adipose-derived stromal cells ADSCs prepared from human cheek fat pads2010
- Author(s)
  Shiraishi T, Ikeda H, Sumita Y, Ohba S, Wakamatu Y, Nagai K, Asahina I
- Organizer
  Asian Congress on Oral & Maxillofacial Surgery
- Place of Presentation
  Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-23659952
[Presentation] Bone regeneration using adipose-derived stromal cells ADSCS prepared from human cheek fat pads2010
- Author(s)
  T Shiraishi, Y Sumita, H Ikeda, S Ohba, I Asahina
- Organizer
  Asian Congress on Oral & Maxillofacial Surgery
- Place of Presentation
  Kuala Lumpu
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] Bone regeneration using adipose-derived stromal cells ADSCs prepared from human cheek fat pads2010
- Author(s)
  Shiraishi T, Ikeda H, Sumita Y, Ohba S, Wakamatu Y, Nagai K, Asahina I
- Organizer
  Asian Congress on Oral & Maxillofacial Surgery
- Place of Presentation
  Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-22390387
[Presentation] 遺伝子活性化基質（GAM)を用いた骨再生促進システムの開発
- Author(s)
  梅林真由美、住田吉慶、河井洋祐、朝比奈泉
- Organizer
  日本口腔外科学会総会・学術大会
- Place of Presentation
  幕張メッセ（千葉県）
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25293413
[Presentation] 血管内皮前駆細胞を主体とした末梢血濃縮細胞群による萎縮唾液腺再生療法の開発
- Author(s)
  井隆司、住田吉慶、増田治史、浅原孝之、朝比奈泉
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25670864
[Presentation] 骨髄濃縮液による骨組織再生の試み
- Author(s)
  江頭寿洋、住田吉慶、三浦桂一郎、中谷佑哉、朝比奈泉
- Organizer
  第44回日本口腔インプラント学会
- Place of Presentation
  国際フォーラム（東京都）
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25670863

1. ASAHINA Izumi (30221039)

# of Collaborated Projects: 17 results

# of Collaborated Products: 58 results
2. KUROSHIMA Shinichiro (40443915)

# of Collaborated Projects: 13 results

# of Collaborated Products: 8 results
3. KAGAMI Hideaki (80242866)

# of Collaborated Projects: 11 results

# of Collaborated Products: 21 results
4. NISHIMURA Masahiro (00294570)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
5. 佐々木宗輝 (10706336)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
6. KOMORI Toshifumi (00252677)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. SAWASE Takashi (80253681)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
8. OTSUKA Masato (90372945)

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9. 松本拡高 (90782045)

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10. AGATA Hideki (20581177)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
11. RI Kenki (60350831)

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12. OHBA Seigo (80363456)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
13. NAKAJIMA Kazunori (40707246)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
14. IWATAKE Mayumi (40624614)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
15. 井隆司 (30733448)

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# of Collaborated Products: 2 results
16. NAGAI Kazuhiro (30304942)

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17. SUEHIRO Fumio (40524781)

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18. ISHISAKI Akira (20356439)

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19. Miura Kei-ichiro (10634446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
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58. 上原雅隆

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SUMITA Yoshinori 住田 吉慶

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組織マクロファージの動的恒常性維持機能を標的軸としたデザイナー細胞医薬の開発Principal Investigator

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iPS細胞由来巨核球を骨誘導のデザイナー細胞として応用した新しい骨再生治療開発Principal Investigator

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SUMITA Yoshinori 住田吉慶