NAGAI Kazuhiro 長井一浩

… Alternative Names

長井一浩ナガイカズヒロ

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Researcher Number	30304942
Other IDs
External Links
Affiliation (Current)	2022: 長崎大学, 病院(医学系), 准教授
Affiliation (based on the past Project Information) *help	2021: 長崎大学, 病院(医学系), 准教授 2019 – 2020: 長崎大学, 病院(医学系), 講師 2015 – 2017: 長崎大学, 病院(医学系), 講師 2012: 長崎大学, 病院, 講師 2011 – 2012: 長崎大学, 大学病院, 講師 … More 2011: 長崎大学, 長崎大学病院, 准教授 2010: 長崎大学, 病院, 准教授 2007 – 2008: 長崎大学, 医学部・歯学部附属病院, 講師 2004 – 2005: 長崎大学, 医学部・歯学部附属病院, 講師 2002: Nagasaki University Hospital, Lecturer, 医学部附属病院, 講師 2001: Nagasaki University Hospital, Lecturer, 医学部・附属病院, 講師 2000 – 2001: 長崎大学, 医学部・附属病院, 助手 1998: 長崎大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Hematology / Digestive surgery Except Principal Investigator Hematology / Risk sciences of radiation/Chemicals / Prosthetic dentistry / Surgical dentistry / Basic Section 55040:Respiratory surgery-related
Keywords	Principal Investigator leukemic progenitor cell / adhesion molecule / signal transduction / side population cell / bone marrow / stem cell / hematopoiesis / myelodysplastic syndrome / aplastic anemia / PNH … More / ABCG2 / Adult T-cell Leukemia / Adult T-cell leukemia / paroxysmal nocturnal hemoglobinemia / myelod splastic syndrome / 腫瘍免疫 / 膵臓癌 / 腫瘍微小環境 / バイオマーカー / 樹状細胞 / イムノコンプレキソーム … More Except Principal Investigator adhesion molecule / 幹細胞 / 再生医療 / ATL / cobblestone area / signal transduction / autocrine / 放射線被ばく / 放射線誘発遅延性ゲノム不安定状態 / 発がん機構 / 骨再生 / 間葉系幹細胞 / 歯槽骨再生 / 骨増生 / 唾液腺再生 / 神経堤細胞 / 相互作用 / 唾液腺萎縮 / 唾液腺 / 再生 / ストローマ細胞 / 長期共培養系 / Cobble stone area / 接着分子 / シグナル伝達 / cobble stone area / stromal cells / long-term coculture sytem / adult T-cell leukemia / vascular endotherial growth factor / leukemic progenitor cell / signal transuduction / Adult T -cell leukemia / Vascular Endotherial Growth Factor / leukemic progenitor cells / 羊膜 / 胸膜 / 癒着防止 / 中皮 / 中皮細胞 / 胸膜癒着 / 胸膜欠損 / 悪性胸膜中皮腫 / 肺瘻 / 気管支瘻 Less

Development of a Novel Respiratory Surgical Coating Material Using Freeze- and Vaccum-Dried Human Amniotic Membranes
- Principal Investigator
  
  Nagayasu Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
Comprehensive influence on tumor immune system by interaction between pancreatic cancer and molecules of tumor microenvironment.Principal Investigator
- Principal Investigator
  
  NAGAI Kazuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagasaki University
Development of cell therapy for the salivary gland tissue regeneration with direct reprogrammed dental mesenchymal cells
- Principal Investigator
  
  SUMITA Yoshinori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Alveolar bone engineering using alveolar bone marrow derived mesenchymal stem cells
- Principal Investigator
  
  NISHIMURA Masahiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Prosthetic dentistry
- Research Institution
  Nagasaki University
放射線被ばくによるヒト体性幹細胞におけるゲノム不安定性の研究
- Principal Investigator
  
  TOMANAGA Masao
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nagasaki University
Characterization of side population cells in bone marrow of myelodysplastic syndrome, aplastic anemia, and paroxysmal nocturnal hemoglobinuria.Principal Investigator
- Principal Investigator
  
  NAGAI Kazuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagasaki University
Significance of autocrine mechanism of VEGF/VEGF receptor in ATL cell proliferation.
- Principal Investigator
  
  TOMONAGA Masao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagasaki University
Adhesion-dependent growth of ATL cells ; significance of signaling pathway through adhesion moleculesPrincipal Investigator
- Principal Investigator
  
  NAGAI Kazuhiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Nagasaki
Proliferation of ATL cells without production of HTLV-1 related proteins: JAK/STAT system using coculture method with stromal cells
- Principal Investigator
  
  JINNAI Itsuro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  NAGASAKI UNIVERSITY SCHOOL OF MEDICINE

All 2018 2017 2016 2015 2007 2005 2004 Other

All Journal Article Presentation Book

[Book] The Second Nagasaki Symposium of International Consortium for Medical Care of Hibakusha and Radiation Life Science.
- Author(s)
  Nagai K, Miyazaki Y, Tomonaga M, et al.
- Publisher
  Therapeutic angiogenesis by autologous transplantation of bone marrow mononuclear cells for peripheral artery disease.(in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590945
[Journal Article] WT1-pulsed dendritic cell vaccine combined with chemotherapy for resected pancreatic cancer in a phase I study.2018
- Author(s)
  Yanagisawa R, Koizumi T, Koya T, Sano K, Koido S, Nagai K, Kobayashi M, Okamoto M, Sugiyama H, Shimodaira S.
- Journal Title
  
  Anticancer Res
  
  Volume: 38 Pages: 2217-2225
- DOI
  10.21873/anticanres.12464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10021, KAKENHI-PROJECT-15K10190, KAKENHI-PROJECT-16K15829, KAKENHI-PROJECT-17H04410
[Journal Article] The donor advocacy team: a risk management program for living organ, tissue, and cell transplant donors.2017
- Author(s)
  Eguchi S, Soyama A, Nagai K, Miyazaki Y, Kurihara S, Hidaka M, Ono S, Adachi T, Natsuda K, Hara T, Fujita F, Kanetaka K, Takatsuki M.
- Journal Title
  
  Surg Today
  
  Volume: 印刷中
- DOI
  10.1007/s00595-017-1468-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10190
[Journal Article] Lung adenocarcinoma may be a more susceptive subtype to a dendritic cell-based cancer vaccine than other subtypes of non-small cell lung cancers: a multicenter retrospective analysis2016
- Author(s)
  Takahashi H, Shimodaira S, Ogasawara M, Ota S, Kobayashi M, Abe H, Morita Y, Nagai K, Tsujitani S, Okamoto M, Suzuki Y, Nakanishi Y, Yonemitsu Y
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 65 Pages: 1099-111
- DOI
  10.1007/s00262-016-1872-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10190, KAKENHI-PROJECT-16K15829
[Journal Article] Therapeutic angiogenesis by autologous transplantation of bone marrow mononuclear cells for peripheral artery disease.2007
- Author(s)
  Nagai K, Miyazaki Y, Tomonaga M, et al.
- Journal Title
  
  The Second Nagasaki Symposium of International Consortium for Medical Care of Hibakusha and Radiation Life Science. (in press)
- NAID
  130007000012
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590945
[Journal Article] Characterization of side population in thyroid cancer cell lines : cancer stem-like cells are enriched partly but not exclusively.2007
- Author(s)
  Mitsutake N, Nagai K, et al.
- Journal Title
  
  Endocrinology 148
  
  Pages: 1797-1803
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590945
[Journal Article] An ATL cell line with an IgH pseudo-rearranged band pattern by southern blotting a pitfall of genetic diagnosis.2005
- Author(s)
  Uemura A, Nagai K, et al.
- Journal Title
  
  Jab Hematol. 11(1)
  
  Pages: 8-13
- Data Source
  KAKENHI-PROJECT-16590945
[Journal Article] Proviral status of HTLV-1 integrated into the host genomic DNA of adult T-cell leukemia cells.2005
- Author(s)
  Kamihira S, Nagai K, et al.
- Journal Title
  
  Clin Lab Haematol. 27(4)
  
  Pages: 235-241
- Data Source
  KAKENHI-PROJECT-16590945
[Journal Article] Establishment of a clonal human mesenchymal cell line that retains multilineage differentiation capacity from a spinal hamartoma.2004
- Author(s)
  Doiguchi Y, Nagai K, et al.
- Journal Title
  
  Cell Tissue Res. 317
  
  Pages: 237-246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590945
[Journal Article] Establishment of a clonal human mesenchymal cell line that retains multilineage differentiation capacity from a spinal hamartoma.2004
- Author(s)
  Doiguchi Y, Nagai K.et a.
- Journal Title
  
  Cell Tissue Res. 317
  
  Pages: 237-246
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590945
[Presentation] 局所進行膵癌に対するオーダーメードの治療戦略　術前治療から術後補助療法まで2016
- Author(s)
  北里周, 黒木保, 大野慎一郎, 黒島直樹, 平山昂仙, 川上悠介, 今村一歩, 岡田怜美, 夏田孔史, 曽山明彦, 日高匡章, 長井一浩, 江口晋
- Organizer
  第28回日本肝胆膵外科学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2016-06-02
- Data Source
  KAKENHI-PROJECT-15K10190
[Presentation] 樹状細胞ワクチンを投与された非小細胞肺癌患者260例の解析と化学療法併用における免疫チェックポイント分子の意義2016
- Author(s)
  岡本正人、高橋秀徳、下平滋隆、小笠原正浩、小林正学、阿部浩文、森田祐二、長井一浩、辻谷俊一、米満吉和
- Organizer
  第29回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  久留米シティプラザ（福岡県・久留米市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K10190
[Presentation] 遠隔転移を認めるIV期癌の治療戦略進行癌に対するがん免疫療法の展開　免疫チェックポイント阻害薬と樹状細胞ワクチン2016
- Author(s)
  辻谷俊一, 下平滋隆, 岡本正人, 米満吉和, 小笠原正浩, 長井一浩, 小井戸薫雄, 小林正学
- Organizer
  第54回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-20
- Data Source
  KAKENHI-PROJECT-15K10190
[Presentation] 樹状細胞免疫療法が有効であったHIVキャリアに発症した細胆管癌の一症例2016
- Author(s)
  長井一浩
- Organizer
  第5回日本免疫・細胞治療学会学術集会
- Place of Presentation
  秋葉原UDX（東京都・千代田区）
- Data Source
  KAKENHI-PROJECT-15K10190
[Presentation] 治癒切除後膵臓癌に対するWT1およびMUC1ペプチドパルス樹状細胞免疫療法の術後アジュバント療法としての有用性2015
- Author(s)
  長井一浩、北里　周、原田　浩、足立智彦、黒木　保、岡本正人、宮崎泰司、江口　晋
- Organizer
  第28回日本バイオセラピー学会総会
- Place of Presentation
  川越東武ホテル，埼玉県川越市
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K10190
[Presentation] 進行期非小細胞肺癌患者に対する樹状細胞ワクチンによる臨床的有用性および予後因子の検討：多施設共同研究2015
- Author(s)
  高橋秀徳、下平滋隆、小笠原正浩、小林正学、阿部浩文、長井一浩、岡本正人、辻谷俊一、森田祐二、米満吉和
- Organizer
  第28回日本バイオセラピー学会総会
- Place of Presentation
  川越東武ホテル，埼玉県川越市
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K10190

1. TOMANAGA Masao (40100854)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. JINNAI Itsuro (70162823)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. TUKASAKI Kunihiro (40274659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ASAHINA Izumi (30221039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SUMITA Yoshinori (50456654)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NISHIMURA Masahiro (00294570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOMORI Toshifumi (00252677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KATO Yukio (10112062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MURATA Hiroshi (40229993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUEHIRO Fumio (40524781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAGAMI Hideaki (80242866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. AGATA Hideki (20581177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOJI Takehiko (30170179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HAYASHIBARA Toshihisa (40325634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TSUSHIMA Hideki (70359959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MIYAZAKI Yasushi (40304943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. Nagayasu Takeshi (80284686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 鈴木啓司 (00196809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岩永正子 (00372772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 岡本正人 (10243718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
21. 下平滋隆 (80345751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. 黒木保 (90404219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 土肥良一郎 (00817786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 上松聖典 (30380843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 土谷智史 (30437884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 北岡隆 (80234235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 高木克典 (90635856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 柳沢龍

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGAI Kazuhiro 長井 一浩

長井 一浩 ナガイ カズヒロ

Research Projects

Research Products

Co-Researchers

Development of a Novel Respiratory Surgical Coating Material Using Freeze- and Vaccum-Dried Human Amniotic Membranes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive influence on tumor immune system by interaction between pancreatic cancer and molecules of tumor microenvironment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of cell therapy for the salivary gland tissue regeneration with direct reprogrammed dental mesenchymal cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alveolar bone engineering using alveolar bone marrow derived mesenchymal stem cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

放射線被ばくによるヒト体性幹細胞におけるゲノム不安定性の研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of side population cells in bone marrow of myelodysplastic syndrome, aplastic anemia, and paroxysmal nocturnal hemoglobinuria.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Significance of autocrine mechanism of VEGF/VEGF receptor in ATL cell proliferation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Adhesion-dependent growth of ATL cells ; significance of signaling pathway through adhesion moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proliferation of ATL cells without production of HTLV-1 related proteins: JAK/STAT system using coculture method with stromal cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] The Second Nagasaki Symposium of International Consortium for Medical Care of Hibakusha and Radiation Life Science.

Author(s)

Publisher

Description

Data Source

[Journal Article] WT1-pulsed dendritic cell vaccine combined with chemotherapy for resected pancreatic cancer in a phase I study.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The donor advocacy team: a risk management program for living organ, tissue, and cell transplant donors.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lung adenocarcinoma may be a more susceptive subtype to a dendritic cell-based cancer vaccine than other subtypes of non-small cell lung cancers: a multicenter retrospective analysis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic angiogenesis by autologous transplantation of bone marrow mononuclear cells for peripheral artery disease.2007

NAGAI Kazuhiro 長井一浩

長井一浩ナガイカズヒロ

[Presentation] 局所進行膵癌に対するオーダーメードの治療戦略　術前治療から術後補助療法まで2016

[Presentation] 遠隔転移を認めるIV期癌の治療戦略進行癌に対するがん免疫療法の展開　免疫チェックポイント阻害薬と樹状細胞ワクチン2016