TSUCHIYA Tomoshi 土谷智史

… Alternative Names

Researcher Number	30437884
Other IDs
External Links
Affiliation (Current)	2019: 長崎大学, 医歯薬学総合研究科(医学系), 准教授
Affiliation (based on the past Project Information) *help	2014 – 2019: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2014: 長崎大学, 医歯薬学総合研究科(医学系), 講師 2013: 長崎大学, 大学院医歯薬学総合研究科, 講師 2011 – 2013: 長崎大学, 医歯(薬)学総合研究科, 講師 2010: 長崎大学, 医学部・歯学部付属病院, 講師 … More
Review Section/Research Field	Principal Investigator Respiratory surgery / Thoracic surgery / Tumor biology and related fields / Basic Section 55040:Respiratory surgery-related Except Principal Investigator Thoracic surgery / Respiratory surgery / Basic Section 55040:Respiratory surgery-related / Digestive surgery
Keywords	Principal Investigator 肺再生 / 肺 / 脱細胞化 / 再細胞化 / 肺移植 / マトリックス / 移植・再生医療 / 組織工学 / 再生 / 肺気腫 … More Except Principal Investigator 肺移植 / KGF / 人工気管 / 外科 / 創傷治癒 / 再生医療 / 免疫寛容 / 羊膜 / 拒絶 / 制限増殖アデノウイルス / cisplatin / 悪性胸膜中皮腫 / 移植・再生医療 / 細胞シート / 気道狭窄 / 脂肪幹細胞 / TTF1 / array CGH / DPD / 臓器保存 / Surfactant protein A / 人工赤血球 / KRas / surfactant protein / 量子ドット / Sp1 / GFP rat / Gefitinib / exome解析 / non small cell lung cancer / emphysema / adenovirus / 肺瘻 / 肺再生 / 気管支瘻 / 気管創傷治癒 / 人工臓器 / intratracheal administration / 呼吸器外科学 / 虚血再灌流生涯 / 家族性肺癌 / バイオ３Dプリンター / EGFR / 幹細胞 / 肺気腫 / 代償性肺肥大 / 難治性気道疾患 / Thyroid transcription factor 1 / 進行肺癌 / 染色体構造変化 / 肺内転移 / 原発多発肺癌 / グルココルチコイド / NSCLC / 再生医学 / 肺癌 / 非小細胞肺癌 / 気管 / 肺胞サーファクタント / GFP / 肺前駆細胞 / regeneration / 気管軟骨 / 気道再生 / Thyriod transcription factor 1 / 再生 / 臓器保護 / 同時多発肺癌 Less

組織骨格を利用した再生臓器におけるハイブリッド型血管ニッチの確立と移植研究Principal InvestigatorOngoing
- Principal Investigator
  
  土谷智史
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
凍結および真空乾燥ヒト羊膜を利用した新規呼吸器外科領域被覆材の創製Ongoing
- Principal Investigator
  
  永安武
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
Development of rejection control method by mesenchymal stem cells using original rat lung transplantation modelOngoing
- Principal Investigator
  
  宮崎拓郎
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
Scaffold-free artificial trachea for tracheal deiseasesOngoing
- Principal Investigator
  
  松本桂太郎
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagasaki University
Generation of the small human lungs as the novel ex vivo lung cancer study modelsPrincipal InvestigatorOngoing
- Principal Investigator
  
  土谷智史
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Challenging Research (Exploratory)
- Research Field
  
  Tumor biology and related fields
- Research Institution
  Nagasaki University
自己細胞および幹細胞を用いた人工食道作製による再生医療Ongoing
- Principal Investigator
  
  谷口大輔
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagasaki University
人工赤血球が持つ肺虚血再還流障害抑制効果の臨床応用を目指した、臓器保護の研究Ongoing
- Principal Investigator
  
  宮崎拓郎
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Nagasaki University
Transplantation studies of tissue engineered tracha and lung regenerated from recellularized xenogeneic-decellularized scaffoldPrincipal InvestigatorOngoing
- Principal Investigator
  
  土谷智史
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Nagasaki University
Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer
- Principal Investigator
  
  NAGAYASU Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Nagasaki University
Basic researches for the improvement of the fragility and the organ portection about de-and re-cellularization based regenerated lungPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Nagasaki University
Germline mutations causing familial lung cancer
- Principal Investigator
  
  MIYAZAKI Takuro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Nagasaki University
Novel method for tracheal diseases and pulmonary diseases
- Principal Investigator
  
  MATSUMOTO Keitaro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Nagasaki University
The study of tissue protection and cell implantation effects by adipose tissue derived stromal cells for future usage in damaged or transplanted lungPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nagasaki University
New role of stem cells in the GFP-rat lung transplantation model
- Principal Investigator
  
  YAMASAKI Naoya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nagasaki University
Establishment of therapeutic strategy for synchronous double lung cancers based on molecular analysis
- Principal Investigator
  
  NAGAYASU Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nagasaki University
Targeting advanced non small cell lung cancer in vivo by pulmonary surfactant -adenovirus-mediated gene transfer
- Principal Investigator
  
  MATSUOKA Jyunji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
A examination of KGF seat to prevent bronchpleural fistula.
- Principal Investigator
  
  NAGAYASU Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nagasaki University
The effects of adiponectin on lung cancer and lung diseasePrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nagasaki University
Gene therapy for lung emphysema
- Principal Investigator
  
  NAGAYASU Takeshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nagasaki University

All 2018 2017 2016 2015 2014 2012 Other

All Journal Article Presentation

[Journal Article] Transplantation of bioengineered rat lungs recellularized with endothelial and adipose-derived stromal cells.2017
- Author(s)
  Doi Ryoichiro, Tsuchiya Tomoshi, Mitsutake Norisato, Nishimura Satoshi, Matsuu-Matsuyama Mutsumi, Nakazawa Yuka, Ogi Tomoo, Akita Sadanori, Yukawa Hiroshi, Baba Yoshinobu, Yamasaki Naoya, Matsumoto Keitaro, Miyazaki Takuro, Kamohara Ryotaro, Hatachi Go, Sengyoku Hideyori et al.
- Journal Title
  
  Scientific Reports (Nature Publishing Group)
  
  Volume: 7 Pages: 1-15
- DOI
  10.1038/s41598-017-09115-2
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00554, KAKENHI-PROJECT-15H05333, KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-15H04944
[Journal Article] Ventilation-Based Decellularization System of the Lung.2016
- Author(s)
  Tsuchiya T, Mendez J, Calle EA, Hatachi G, Doi R, Zhao L, Suematsu T, Nagayasu T, Niklason LE.
- Journal Title
  
  Biores Open Access.
  
  Volume: 5 Pages: 118-126
- DOI
  10.1089/biores.2016.0012
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670629
[Journal Article] Germline mutations causing familial lung cancer.2015
- Author(s)
  Tomoshige K, Matsumoto K, Tsuchiya T, Oikawa M, Miyazaki T, Yamasaki N, Mishima H, Kinoshita A, Kubo T, Fukushima K, Yoshiura K, Nagayasu T
- Journal Title
  
  J Hum Genet
  
  Volume: 60 Pages: 597-603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462180
[Journal Article] Poly(ADP-ribose) Polymerase Inhibitor (PJ34) Reduces Pulmonary Ischemia-Reperfusion Injury in Rats2014
- Author(s)
  Go Hatachi, Tomoshi Tsuchiya, Takuro Miyazaki, Keitaro Matsumoto, Naoya Yamasaki, Shingo Matsushima, Atsushi Nanashima, Yoshikazu Higami, and Takeshi Nagayasu
- Journal Title
  
  Transplantation
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592066
[Journal Article] Clinical and molecular analysis of synchronous double lung cancers2012
- Author(s)
  Junichi Arai, Tomoshi Tsuchiya, Masahiro Oikawa, Koji Mochinaga, Tomayoshi Hayashi, Koh-ichiro Yoshiura, Kazuhiro Tsukamoto, Naoya Yamasaki, Keitaro Matsumoto, Takuro Miyazaki, Takeshi Nagayasu
- Journal Title
  
  Lung Cancer
  
  Volume: 77 Pages: 281-287
- Data Source
  KAKENHI-PROJECT-23592068
[Presentation] Remodeling the vasculature in the decellularized lung scaffold using adipogenic stromal cells2018
- Author(s)
  土谷智史
- Organizer
  第5回国際組織工学・再生医療学会世界会議2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04944
[Presentation] 3次元構築を保った肺再生の取り組みとヒト肺創出への道2018
- Author(s)
  土谷智史
- Organizer
  第17回再生医療学会
- Data Source
  KAKENHI-PROJECT-15H04944
[Presentation] Potential of Adipose-Derived Stem/Stromal Cells for Lung Transplantation and Lung Tissue Engineering2018
- Author(s)
  土谷智史
- Organizer
  American Thoracic Society 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04944
[Presentation] 脱細胞組織骨格を利用した肺の再生法とその問題点2017
- Author(s)
  土谷智史
- Organizer
  第40回呼吸器内視鏡学会
- Data Source
  KAKENHI-PROJECT-15H04944
[Presentation] 臓器再生第一段階としての肺-脱細胞化組織骨格内の血管網の構築2016
- Author(s)
  土谷智史
- Organizer
  第43回日本臓器保存学会
- Place of Presentation
  東京薬科大学(東京都八王子市)
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-26670629
[Presentation] 臓器再生第一段階としての肺-脱細胞化組織骨格内の血管網の構築2016
- Author(s)
  土谷智史
- Organizer
  第43回日本臓器保存生物医学会学術集会
- Place of Presentation
  東京薬科大学　(東京都八王子市)
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15H04944
[Presentation] 非小細胞肺癌にｐけるEGR変異とDPDおよびその関連因子に関する検討2015
- Author(s)
  富永哲郎,土谷智史,朝重耕一,畑地　豪,荒井淳一,宮﨑拓郎,松本桂太郎,山崎直哉,永安　武
- Organizer
  日本臨床分子形態学会
- Place of Presentation
  長崎大学(長崎県長崎市)
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-26462130
[Presentation] 間歇的圧変化を利用した、気管からのラット肺脱細胞化法2015
- Author(s)
  土谷智史
- Organizer
  第51回日本移植学会総会
- Place of Presentation
  ホテル日航熊本(熊本県・熊本市）
- Year and Date
  2015-10-01
- Data Source
  KAKENHI-PROJECT-26670629
[Presentation] 同時多発肺腫瘍のarray-comparative-genomic-hybridization(aCG H)を用いた細胞遺伝学的検索と予後解析2012
- Author(s)
  荒井淳一、及川将弘、土谷智史、宮崎拓郎、松本桂太郎、山崎直哉、林徳眞吉、吉浦孝一郎、永安武
- Organizer
  第29回日本呼吸器外科学会
- Place of Presentation
  秋田キャッスルホテル
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-23592068
[Presentation] 次世代シーケンサーを用いたエキソーム解析による家族性肺癌責任遺伝子の同定
- Author(s)
  朝重耕一、宮崎拓郎、松本桂太郎、土谷智史、山崎直哉、永安武
- Organizer
  第113回　日本外科学会
- Place of Presentation
  福岡国際会議場(福岡市)
- Data Source
  KAKENHI-PROJECT-25462180
[Presentation] NaOH-PBS によるラット肺の脱細胞化・再細胞化
- Author(s)
  扇玉秀順, 土谷智史, 山崎直哉, 松本桂太郎, 宮﨑拓郎, 永安武
- Organizer
  第41回日本臓器保存生物医学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府）
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-26670629

1. NAGAYASU Takeshi (80284686)

# of Collaborated Projects: 18 results

# of Collaborated Products: 9 results
2. YAMAZAKI Naoya (70404217)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
3. MATSUMTO Keitaro (80404268)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
4. MIYAZAKI Takuro (00584749)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
5. HIGAMI Yoshikazu (90253640)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
6. TAGAWA Tsutomu (20363492)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SHIMOKAWA Isao (70187475)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. AKITA Sadanori (90315250)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
9. 李桃生 (50379997)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. 土肥良一郎 (00817786)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. 畑地豪 (80437889)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 中山功一 (50420609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 田浦康明 (60437887)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. MATSUOKA Jyunji (30332795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. FUKAZAWA Takuya (20379845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ONO Toshiro (50185641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MOMINOKI Katsumi (70304615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TANAKA Noriaki (10127566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMATSUJI Tomoki (40379730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAOMOTO Yoshio (00237190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TANAKA Hirotosh (00171794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YANO Hiroshi (50380887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KUBO Toru (50444873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 及川将弘 (90612416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. 日高重和 (30380885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 小林英司 (00245044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 濱田聖暁 (30796181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 酒井宏水 (70318830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 谷口大輔 (20773758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 國崎真己 (10533747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 山本和子 (10398167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 鳴瀧彩絵 (10508203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 湯川博 (30634646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 諸藤陽一 (40437869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 長井一浩 (30304942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 上松聖典 (30380843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 北岡隆 (80234235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 高木克典 (90635856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 渡邉洋之助 (30457551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. NAKAZAWA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 松鵜睦美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 馬場嘉信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 荻朋男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 光武範吏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TSUCHIYA Tomoshi 土谷 智史

TSUTYA Tomoshi 土谷 智史

Research Projects

Research Products

Co-Researchers

組織骨格を利用した再生臓器におけるハイブリッド型血管ニッチの確立と移植研究Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

凍結および真空乾燥ヒト羊膜を利用した新規呼吸器外科領域被覆材の創製Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of rejection control method by mesenchymal stem cells using original rat lung transplantation modelOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Scaffold-free artificial trachea for tracheal deiseasesOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of the small human lungs as the novel ex vivo lung cancer study modelsPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

自己細胞および幹細胞を用いた人工食道作製による再生医療Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

人工赤血球が持つ肺虚血再還流障害抑制効果の臨床応用を目指した、臓器保護の研究Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transplantation studies of tissue engineered tracha and lung regenerated from recellularized xenogeneic-decellularized scaffoldPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic researches for the improvement of the fragility and the organ portection about de-and re-cellularization based regenerated lungPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of tissue protection and cell implantation effects by adipose tissue derived stromal cells for future usage in damaged or transplanted lungPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TSUCHIYA Tomoshi 土谷智史

TSUTYA Tomoshi 土谷智史