ARIHARA Yohei 在原洋平

… Alternative Names

在原洋平アリハラヨウヘイ

Less

Researcher Number	30749586
Other IDs	https://orcid.org/0009-0001-7673-3724
Affiliation (Current)	2025: 公益財団法人がん研究会, 有明病院先端医療開発科 , 副医長 2025: 札幌医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2023: 公益財団法人がん研究会, 有明病院先端医療開発科, 副医長 2022 – 2023: 札幌医科大学, 医学部, 研究員 2016 – 2018: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Tumor therapeutics
Keywords	Principal Investigator BH3 profiling / ICI / Head and Neck Cancer / がん免疫 / 免疫チェックポイント阻害剤 / 頭頸部扁平上皮癌 Except Principal Investigator Immunotherapy / HCC / BRG1 / NRF2 … More / 酸化ストレス / 骨髄ホーミング / 浸潤 / 転移 / 活性酸素種 / STEAP1 / 多発性骨髄腫 Less

Understanding the immune landscape and developing predictive biomarkers for HNSCC treated with ICIsPrincipal Investigator
- Principal Investigator
  
  在原洋平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Development a novel immnunotherapy for hepatocellular carcinoma targeted by BRG1
- Principal Investigator
  
  高田弘一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Reactive oxygen species play roles in multiple myeloma pathogenesis
- Principal Investigator
  
  Kohichi Takada
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University

All 2024 2023 2018 2017 2016

All Journal Article Presentation

[Journal Article] ST2825, independent of MyD88, induces reactive oxygen species-dependent apoptosis in multiple myeloma cells2024
- Author(s)
  Nakamura Hajime、Arihara Yohei、Usami Makoto、Takada Kohichi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 38 Pages: 101681-101681
- DOI
  10.1016/j.bbrep.2024.101681
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080
[Journal Article] Gap junction beta‐4 accelerates cell cycle progression and metastasis through MET?AKT activation in pancreatic cancer2024
- Author(s)
  Muramatsu Joji、Arihara Yohei、Yoshida Makoto、Kubo Tomohiro、Nakamura Hajime、Ishikawa Kazuma、Fujita Hiromi、Sugita Shintaro、Konno Takumi、Kojima Takashi、Kawano Yutaka、Kobune Masayoshi、Takada Kohichi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 1564-1575
- DOI
  10.1111/cas.16101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-22K08509
[Journal Article] Simultaneous XIAP and cIAP1/2 inhibition by a dimeric SMAC mimetic AZD5582 induces apoptosis in multiple myeloma2024
- Author(s)
  Kikuchi Shohei、Sugama Yusuke、Takada Kohichi、Kamihara Yusuke、Wada Akinori、Arihara Yohei、Nakamura Hajime、Sato Tsutomu
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 1 Pages: 30-36
- DOI
  10.1016/j.jphs.2023.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080
[Journal Article] Inflammation and malnutrition as markers of poor outcomes in head and neck cancer patients treated with nivolumab2023
- Author(s)
  Arihara Yohei、Takada Kohichi、Murase Kazuyuki、Kawamura Kentaro、Kakiuchi Akito、Kurose Makoto、Sasaki Takanori、Ogi Kazuhiro、Yamazaki Masahide、Miyazaki Akihiro、Kato Junji、Takano Kenichi
- Journal Title
  
  Acta Oto-Laryngologica
  
  Volume: 143 Issue: 8 Pages: 714-720
- DOI
  10.1080/00016489.2023.2240372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14654, KAKENHI-PROJECT-23K27794
[Journal Article] Six-transmembrane epithelial antigen of the prostate 1 protects against increased oxidative stress via a nuclear erythroid 2-related factor pathway in colorectal cancer2018
- Author(s)
  Nakamura Hajime、Takada Kohichi、Arihara Yohei、Hayasaka Naotaka、Murase Kazuyuki、Iyama Satoshi、Kobune Masayoshi、Miyanishi Koji、Kato Junji
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: - Issue: 9-10 Pages: 313-322
- DOI
  10.1038/s41417-018-0056-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma2017
- Author(s)
  Arihara Yohei、Takada Kohichi、Kamihara Yusuke、Hayasaka Naotaka、Nakamura Hajime、Murase Kazuyuki、Ikeda Hiroshi、Iyama Satoshi、Sato Tsutomu、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 39 Pages: 65889-65899
- DOI
  10.18632/oncotarget.19508
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K09482
[Journal Article] The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.2016
- Author(s)
  Kamihara Y, Murase K, Kato J, et al
- Journal Title
  
  Oncotarget
  
  Volume: 27 Issue: 39 Pages: 64330-64341
- DOI
  10.18632/oncotarget.11830
- NAID
  120006576953
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
[Journal Article] Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells.2016
- Author(s)
  Okagawa Y, Murase K, Kato J, et al
- Journal Title
  
  PLoS One.
  
  Volume: 15 Issue: 12 Pages: e0168355-e0168355
- DOI
  10.1371/journal.pone.0168355
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
[Presentation] p53-restoring small molecule CP-31398 induced apoptosis via induction of reactive oxidative species in human multiple myeloma2017
- Author(s)
  Yohei Arihara, Kohichi Takada
- Organizer
  European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178

1. Kohichi Takada (90398321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 加藤淳二 (20244345)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 村松丈児 (30933733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. MURASE Kazuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

ARIHARA Yohei 在原 洋平

在原 洋平 アリハラ ヨウヘイ

Research Projects

Research Products

Co-Researchers

Understanding the immune landscape and developing predictive biomarkers for HNSCC treated with ICIsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development a novel immnunotherapy for hepatocellular carcinoma targeted by BRG1

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reactive oxygen species play roles in multiple myeloma pathogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ST2825, independent of MyD88, induces reactive oxygen species-dependent apoptosis in multiple myeloma cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gap junction beta‐4 accelerates cell cycle progression and metastasis through MET?AKT activation in pancreatic cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simultaneous XIAP and cIAP1/2 inhibition by a dimeric SMAC mimetic AZD5582 induces apoptosis in multiple myeloma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inflammation and malnutrition as markers of poor outcomes in head and neck cancer patients treated with nivolumab2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Six-transmembrane epithelial antigen of the prostate 1 protects against increased oxidative stress via a nuclear erythroid 2-related factor pathway in colorectal cancer2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] p53-restoring small molecule CP-31398 induced apoptosis via induction of reactive oxidative species in human multiple myeloma2017

Author(s)

Organizer

Data Source

ARIHARA Yohei 在原洋平

在原洋平アリハラヨウヘイ