TAKADA Koichi 高田弘一

Researcher Number	90398321
Other IDs
Affiliation *help	2016 – 2018 : 札幌医科大学, 医学部, 講師 2010 – 2017 : 札幌医科大学, 医学部, 助教 2008 : 札幌医大, 医学部, 助教 2007 – 2008 : Sapporo Medical University, 医学部, 助教 2006 : 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Hematology / Tumor therapeutics Except Principal Investigator Biological Sciences / Hematology / Gastroenterology / Tumor therapeutics
Keywords	Principal Investigator 多発性骨髄腫 / BCL9 / Wnt シグナル / 鉄吸収試験 / 酸化ストレス / 鉄代謝 / Hepcidin / 抗大腸癌ペプチド / STEAP1 / NASH / Wntシグナル / 除鉄療法 … More Except Principal Investigator … More

細胞の糖代謝特性を利用した新規大腸癌治療法の開発Ongoing
- Principal Investigator
  
  加藤淳二
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
酸化ストレスによる多発性骨髄腫病態修飾機序の解析および新規治療法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  高田弘一
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
The effect of exosomal miRNA on AML/MDS stromal cells
- Principal Investigator
  
  小船雅義
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Identifing novel therapeutic target molecules in multiple myeloma using BCL9-ChIPSeqPrincipal Investigator
- Principal Investigator
  
  Takada Kohichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Targeted disruption of the BCL9/beta-catenin complex in colorectal cancer using stapled peptidePrincipal Investigator
- Principal Investigator
  
  TAKADA Kohichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
癌随伴線維芽細胞を標的としたがん治療法の開発
- Principal Investigator
  
  瀧本理修
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
A novel anti-fibrotic therapy for scirrhous gastric cancer.
- Principal Investigator
  
  TAKIMOTO Rishu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
非アルコール性脂肪性肝炎発症に関わる鉄代謝異常の分子機構解析と治療法の開発Principal Investigator
- Principal Investigator
  
  高田弘一
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
TGF-βシグナルにお1るプロテインボスフターゼ2Aの癌抑制潰伝子としての意義
- Principal Investigator
  
  TAKIMOTO Rishu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University

All 2017 2016 2015 2014 2013 2012 2011 2007

All Journal Article Presentation Book

[Book] 血液症候群（第２版）　薬剤誘発性赤芽球癆2013
- Author(s)
  高田弘一
- Total Pages
  535
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25461430
[Book] 分子生物学が可能とした個別化医療2012
- Author(s)
  高田弘一
- Data Source
  KAKENHI-PROJECT-23890169
[Book] 臨床消化器内科 NASHにおける鉄代謝異常2007
- Author(s)
  高田弘一
- Total Pages
  6
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-19590780
[Journal Article] Ofatumumab combined with chlorambucil for previously untreated chronic lymphocytic leukemia: a phase I/II, open-label study in Japan2017
- Author(s)
  Hatake Kiyohiko、Ogura Michinori、Takada Kohichi、Taniwaki Masafumi、Zhang Fanghong、Fujita Taizo、Ando Kiyoshi
- Journal Title
  
  Int J Hematol
  
  Volume : 106 Pages : 240-247
- DOI
  10.1007/s12185-017-2233-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma2017
- Author(s)
  Arihara Yohei、Takada Kohichi、Kamihara Yusuke、Hayasaka Naotaka、Nakamura Hajime、Murase Kazuyuki、Ikeda Hiroshi、Iyama Satoshi、Sato Tsutomu、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Oncotarget
  
  Volume : 8 Pages : 65889-65899
- DOI
  10.18632/oncotarget.19508
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K09482
[Journal Article] A phase II study of modified docetaxel, cisplatin, and S-1 (mDCS) chemotherapy for unresectable advanced gastric cancer2017
- Author(s)
  Uemura Naoki、Kikuchi Shohei、Sato Yasushi、Ohnuma Hiroyuki、Okamoto Koichi、Miyamoto Hiroshi、Hirakawa Masahiro、Sagawa Tamotsu、Fujikawa Koshi、Takahashi Yasuo、Okuda Toshinori、Minami Shinya、Takahashi Minoru、Okamoto Tetsuro、Takada Kohichi、Miyanisi Koji、Takayama Tetsuji、Kato Junji
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume : 80 Pages : 707-713
- DOI
  10.1007/s00280-017-3404-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K06857
[Journal Article] Hepatitis C virus reactivation due to antiemetic steroid therapy during treatment of hepatocellular carcinoma2017
- Author(s)
  Kawano Yutaka、Miyanishi Koji、Takahashi Satoshi、Kubo Tomohiro、Ishikawa Kazuma、Sugita Shintaro、Takada Kohichi、Kobune Masayoshi、Hasegawa Tadashi、Kato Junji
- Journal Title
  
  J Infect Chemother
  
  Volume : 23 Pages : 323-325
- DOI
  10.1016/j.jiac.2016.12.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03599
[Journal Article] Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells.2016
- Author(s)
  Okagawa Y, Murase K, Kato J, et al
- Journal Title
  
  PLoS One
  
  Volume : 15
- DOI
  10.1371/journal.pone.0168355
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
[Journal Article] The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.2016
- Author(s)
  Kamihara Y, Murase K, Kato J, et al
- Journal Title
  
  Oncotarget.
  
  Volume : 27 Pages : 64330-64341
- DOI
  10.18632/oncotarget.11830
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
[Journal Article] A phase II trial of small-dose bortezomib, lenalidomide and dexamethasone (sVRD) as consolidation/maintenance therapy in patients with multiple myeloma.2016
- Author(s)
  Ibata S, Sato T, Kuroda H, Nagamachi Y, Iyama S, Fujimi A, Kamihara Y, Konuma Y, Yoshida M, Tatekoshi A, Hashimoto A, Horiguchi H, Ono K, Murase K, Takada K, Miyanishi K, Kobune M, Hirayama Y, Kato J.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume : 78 Pages : 1041-1049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Narrow-Band Ultraviolet B Phototherapy Ameliorates Acute Graft-Versus-Host Disease of the Intestine by Expansion of Regulatory T Cells2016
- Author(s)
  Hashimoto A, Murase K, Kato J. et al
- Journal Title
  
  PLoS One
  
  Volume : 31
- DOI
  10.1371/journal.pone.0152823
- Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461429, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26670178, KAKENHI-PROJECT-26670386
[Journal Article] Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms.2016
- Author(s)
  Horiguchi H, Murase K, Kato J. et al
- Journal Title
  
  Haematologica
  
  Volume : 101 Pages : 437-447
- DOI
  10.3324/haematol.2015.134932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26670386
[Journal Article] Effect of duloxetine in Japanese patients with chemotherapy-induced peripheral neuropathy: a pilot randomized trial.2015
- Author(s)
  Hirayama Y, Ishitani K, Sato Y, Iyama S, Takada K, Murase K, Kuroda H, Nagamachi Y, Konuma Y, Fujimi A, Sagawa T, Ono K, Horiguchi H, Terui T, Koike K, Kusakabe T, Sato T, Takimoto R, Kobune M, Kato J
- Journal Title
  
  Int J Clin Oncol
  
  Volume : 20 Pages : 866-871
- DOI
  10.1007/s10147-015-0810-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09482, KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430
[Journal Article] BAK is a predictive and prognostic biomarker for the therapeutic effect of docetaxel treatment in patients with advanced gastric cancer.2015
- Author(s)
  Kubo T, Takada K, Kato J, et al
- Journal Title
  
  Gastric Cancer
  
  Volume : 0 Pages : 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Effect of duloxetine in Japanese patients with chemotherapy-induced peripheral neuropathy: a pilot randomized trial2015
- Author(s)
  Hirayama Y, Takada K, Kato J, et al
- Journal Title
  
  Int J Clin Oncol
  
  Volume : 印刷中
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A dose-escalation study of oxaliplatin/capecitabine/irinotecan (XELOXIRI) and bevacizumab as a first-line therapy for patients with metastatic colorectal cancer.2015
- Author(s)
  Sato Y, Ohnuma H, Hirakawa M, Takahashi M, Osuga T, Okagawa Y, Murase K, Takada K, Kawano Y, Iyama S, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Okita K, Mizuguchi T, Furuhata T, Hirata K, Kato J
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume : 75 Pages : 587-597
- DOI
  10.1007/s00280-014-2672-9
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09508
[Journal Article] 10. Increased duodenal iron absorption through up-regulation of divalent metal transporter 1 from enhancement of iron regulatory protein 1 activity in patients with nonalcoholic steatohepatitis.2015
- Author(s)
  Hoki T, Miyanishi K, Kato J, et al.
- Journal Title
  
  Hematology
  
  Volume : 印刷中 Pages : 751-761
- DOI
  10.1002/hep.27774
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591027, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09013, KAKENHI-PROJECT-15K09482, KAKENHI-PROJECT-25461430
[Journal Article] Pazopanibが有効であった転移性横紋筋肉腫の一例2014
- Author(s)
  橋本亜香利，高田弘一，加藤淳二，他
- Journal Title
  
  癌と化学療法
  
  Volume : 0 Pages : 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells2014
- Author(s)
  Tamura F, Takada K, Kato J, et al
- Journal Title
  
  Gastric Cancer
  
  Volume : 印刷中
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Anti-erythropoietin receptor antibody-associated pure red cell aplasia accompanied by Coombs-negative autoimmune hemolytic anemia in a patient with T cell/histiocyte-rich large B cell lymphoma2014
- Author(s)
  Fujimi A, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume : 100 Pages : 490-3
- DOI
  10.1007/s12185-014-1652-5
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Radiation-induced leiomyosarcoma of the prostate after brachytherapy for prostatic adenocarcinoma2014
- Author(s)
  Horiguchi H, Takada K, Kato J, et al
- Journal Title
  
  Case Rep Oncol
  
  Volume : 16 Pages : 565-70
- DOI
  10.1159/000366294
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A novel strategy inducing autophagic cell death in Burkitt's lymphoma cells with anti-CD19-targeted liposomal rapamycin2014
- Author(s)
  Ono K, Takada K, Kato J, et al
- Journal Title
  
  Blood Cancer J
  
  Volume : 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Narrowband ultraviolet B phototherapy ameliorates acute graft-versus-host disease by a mechanism involving in vivo expansion of CD4+CD25+Foxp3+ regulatory T cells2014
- Author(s)
  Iyama S, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume : 0 Pages : 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway2014
- Author(s)
  Zhao JJ, Takada K, Carrasco R, et al
- Journal Title
  
  Cancer Research
  
  Volume : 15 Pages : 1801-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Successful Treatment with Entecavir for Reactivation of Hepatitis B Virus Following Systemic Chemotherapy in a Hepatitis B Surface Antigen-negative Patient with Colorectal Cancer2014
- Author(s)
  Okagawa Y, Takada K, Kato J, et al
- Journal Title
  
  Internal Medicine
  
  Volume : 0 Pages : 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A role for peripherally inserted central venous catheters in the prevention of catheter-related blood stream infections in patients with hematological malignancies2014
- Author(s)
  Sakai T, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume : 100 Pages : 592-8
- DOI
  10.1007/s12185-014-1677-9
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer2014
- Author(s)
  Hashimoto A, Takada K, Kato J, et al
- Journal Title
  
  Case Rep Oncol
  
  Volume : 17 Pages : 316-22
- DOI
  10.1159/000363100
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] リツキシマブが奏効した難治性の混合式自己免疫性溶血性貧血2014
- Author(s)
  小野薫，高田弘一，加藤淳二，他
- Journal Title
  
  臨床血液
  
  Volume : 54 Pages : 2053-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Efficacy of Enteral Supplementation Enriched with Glutamine, Fiber, and Oligosaccharide on Mucosal Injury following Hematopoietic Stem Cell Transplantation2014
- Author(s)
  Iyama S, Sato T, Tatsumi H, Hashimoto A, Tatekoshi A, Kamihara Y, Horiguchi H, Ibata S, Ono K, Murase K, Takada K, Sato Y, Hayashi T, Miyanishi K, Akizuki E, Nobuoka T, Mizuguchi T, Takimoto R, Kobune M, Hirata K, Kato J.
- Journal Title
  
  Case Rep Oncol
  
  Volume : 7 Pages : 692-699
- DOI
  10.1159/000368714
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591427, KAKENHI-PROJECT-25461430
[Journal Article] A case of idiopathic encapsulating peritoneal sclerosis with intractable ileus successfully treated by surgery and steroid therapy2013
- Author(s)
  Ikeda Y, Takada K, Kato J, et al
- Journal Title
  
  Clin J Gastroenterol
  
  Volume : 6 Pages : 295-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker.2013
- Author(s)
  Hirakawa M, Sato Y, Ohnuma H, Takayama T, Sagawa T, Nobuoka T, Harada K, Miyamoto H, Sato Y, Takahashi Y, Katsuki S, Hirayama M, Takahashi M, Ono M, Maeda M, Takada K, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Hirata K, Kato J
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume : 71 Pages : 789-797
- DOI
  10.1007/s00280-013-2073-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24659372
[Journal Article] TRIM13(RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NFKappa B pathway and proteasome activity.2013
- Author(s)
  Gatt ME, Takada K, Mani M, Lerner M, Pick M, Hideshima T, Carrasco DE, Protopopov A, Ivanova E, Sangfelt O, Grander D, Barlogie B, Shaughessy JD Jr, Anderson KC, Carrasco DR
- Journal Title
  
  Br J Haematol
- DOI
  10.1111/bjh.12365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] TRIM13(RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NFKappa B pathway and proteasome activity2013
- Author(s)
  Gatt ME, Takada K, Carrasco DR, et al
- Journal Title
  
  Br J Haematol
  
  Volume : 162 Pages : 21-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Fucosylated TGF-β receptors transduces a signal for epithelial-mesenchymal transition in colorectal cancer cells2013
- Author(s)
  Hirakawa M, Takada K, Kato J, et al
- Journal Title
  
  Br J Cancer
  
  Volume : 110 Pages : 156-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker2013
- Author(s)
  Hirakawa M, Takada K, Kato J, et al
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume : 71 Pages : 789-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Prognostic significance of serum ferritin level at diagnosis in myelodysplastic syndrome.2012
- Author(s)
  Kobune M, et al. 2^<nd>
- Journal Title
  
  Int J Hematol
  
  Volume : (In press) Pages : 527-534
- DOI
  10.1007/s12185-012-1048-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24659372, KAKENHI-PROJECT-24659466
[Journal Article] Intermittent administration of recombinant human soluble thrombomodulin successfully controlled chronic disseminated intravascular coagulation in a patient with dissecting aortic aneurysm on an outpatients basis.2012
- Author(s)
  Iyama S, Sato T, et al.
- Journal Title
  
  Blood Coagul Fibrinolysis
  
  Volume : 23 Pages : 548-50
- DOI
  10.1097/mbc.0b013e32835510d6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591043, KAKENHI-PROJECT-23890169
[Journal Article] 10. Targeting anticancer drug delivery to pancreatic cancer cells using a fucose-bound nanoparticle approach.2012
- Author(s)
  Yoshida M, Takimoto R, Murase K, Sato Y, Hirakawa M, Tamura F, Sato T, Iyama S, Osuga T, Miyanishi K, Takada K, Hayashi T, Kobune M, Kato J.
- Journal Title
  
  PLos One
  
  Volume : 7(7)
- DOI
  10.1371/journal.pone.0039545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590921, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-24659372
[Journal Article] Successful treatment bu fibrin glue sealant for pneumothorax with chronic GVHD resistant to autologous blood patch pleurodesis.2012
- Author(s)
  Iyama S, Sato T, Murase K, Kikuchi S, Kamihara Y, Ono K, Takada K, Miyanishi K, Sato Y, Takimoto R, Kobune M, Obama T, Miyajima M, Watanabe A, Higami T, Hirayama Y, Kato J.
- Journal Title
  
  Intern Med
  
  Volume : 51(15) Pages : 2011-2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Improvement of iron-mediated oxidative DNA damage in patients with transfusion-dependent myelodysplastic syndrome by treatment with deferasirox2012
- Author(s)
  Kikuchi S, Kobune M, Iyama S, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kaneko Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume : 23(6) Pages : 548-550
- DOI
  10.1016/j.freeradbiomed.2012.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24659466
[Journal Article] Targeted Disruption of the BCL9/・-catenin Complex Inhibits Oncogenic Wnt Signaling.2012
- Author(s)
  Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulcinti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR
- Journal Title
  
  Sci Transl Med
  
  Volume : 4(148) Pages : 148-117
- DOI
  10.1126/scitranslmed.3003808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Diagnostic validity of CT gastrography versus gastroscopy for primary lesions in gastric cancer: evaluating the response to chemotherapy, a retrospective analysis.2012
- Author(s)
  Takahashi S, Hirayama M, Kuroiwa G, Kawano Y, Takada K, Sato T, Miyanishi K, Sato Y, Takimoto R, Kobune M, Kato J.
- Journal Title
  
  Gatric Cancer
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms.2012
- Author(s)
  Kobune M, Iyama S, Kikuchi S, Horiguchi H, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kamihara Y, Hayashi T, Miyanishi K, Sato Y, Takimoto R, Kato J.
- Journal Title
  
  Blood Cancer J
- DOI
  10.1038/bcj.2012.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] UGT1A1*28 and *6polymorphisms and nilotinib-induced unconjugated hyperbilirubinemia in a Japanese patient with chronic myelogenous leukemia.2012
- Author(s)
  Takada K, Sato T, Iyama S, Ono K, Kamihara Y, Murase K, Kawano Y, Hayashi T, Miyanishi K, Sato Y, Kobune M, Takimoto R, Kato J
- Journal Title
  
  Int Canc Conf J201
  
  Volume : 1 Pages : 220-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] catenin is dramatically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway.2012
- Author(s)
  Sukhdeo K, Mani M, Hideshima T, Takada K, Pena-Cruz V, Mendez G, Ito S, Anderson KC, Carrasco DR
- Journal Title
  
  Leukemia
  
  Volume : 26(5) Pages : 1116-1119
- DOI
  10.1038/leu.2011.303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Prognostic significance of serum ferritin level at diagnosis in myelodysplastic syndrome2012
- Author(s)
  Kikuchi S, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume : (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Novel missense mutation in the TMPRSS6 gene in Japanese female with iron-refractory deficiency anemia2011
- Author(s)
  Sato T, Takimoto R, Kato J
- Journal Title
  
  Int J Hematol
  
  Volume : 94 Pages : 101-103
- DOI
  10.1007/s12185-011-0881-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231, KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-22591043, KAKENHI-PROJECT-23890169
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M, Takimoto R, Kato, J
- Journal Title
  
  Int J Hematol
  
  Volume : 93 Pages : 715-719
- DOI
  10.1007/s12185-011-0878-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231, KAKENHI-PROJECT-23890169
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume : 93 Pages : 715-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] b-catenin is dramatically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway2011
- Author(s)
  Suhhdeo K, Takada K, Carrasco DR, et al
- Journal Title
  
  Leukemia
  
  Volume : (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Novel missense mutation in the TMPRSS6 gene in a Japanese female with iron-refractory deficiency anemia2011
- Author(s)
  Sato T, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume : 94 Pages : 101-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Iron chelator deferasirox rescued mice from Fas-induced fulminant hepatitis2011
- Author(s)
  Sato T, Takada K, Kato J, et al
- Journal Title
  
  Hepatol Res
  
  Volume : 41 Pages : 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] p53-restoring small molecule CP-31398 induced apoptosis via induction of reactive oxidative species in human multiple myeloma2017
- Author(s)
  Yohei Arihara, Kohichi Takada
- Organizer
  European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Presentation] Exosomal microRNAs in bone marrow cavity induce stromal dysfunction in AML/MDS2015
- Author(s)
  Hiroto Horiguchi, Masayoshi Kobune, Shohei Kikuchi, Kazuyuki Murase, Satoshi Iyama, Kohichi Takada, Tsutomu Sato, Yasushi Sato1), Koji Miyanishi1), Rishu Takimoto, Hiroyuki Kuroda, Masahiro Maeda, Junji Kato
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県金沢市ホテル日航金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K09482
[Presentation] BCL9/beta-catenin 転写複合体を標的とした新規大腸癌治療法の開発2012
- Author(s)
  高田弘一
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] BCL9は大腸癌および多発性骨髄腫において細胞増殖,浸潤・転移能および腫瘍血管新生を亢進させる2011
- Author(s)
  高田弘一, 加藤淳二, Carrasco DR
- Organizer
  第91回北海道医学大会腫瘍系分科会
- Place of Presentation
  札幌医科大学
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] 非アルコール性脂肪性肝炎における鉄代謝異常の分子機構解析2007
- Author(s)
  高田弘一
- Organizer
  第49回日本消化器病学会大会
- Place of Presentation
  神戸
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19590780

1. KATO JUNJI (20244345)

# of Collaborated Projects : 5results

# of Collaborated Products : 33results
2. TAKIMOTO Rishu (10336399)

# of Collaborated Projects : 4results

# of Collaborated Products : 7results
3. SATO Yasushi (80343383)

# of Collaborated Projects : 2results

# of Collaborated Products : 2results
4. KOBUNE MASAYOSHI (90336389)

# of Collaborated Projects : 2results

# of Collaborated Products : 9results
5. KAMIHARA YUSUKE (10624421)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
6. 佐藤勉 (40404602)

# of Collaborated Projects : 1results

# of Collaborated Products : 8results
7. 堀口拓人 (70634674)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. 村瀬和幸 (90444918)

# of Collaborated Projects : 1results

# of Collaborated Products : 8results
9. 在原洋平 (30749586)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 早坂尚貴 (00792665)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. HAYASHI Tsuyoshi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. KIKUCHI Shohei

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
13. Ichimiya Shingo

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. SATO Noriyuki

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
15. HIMI Tetsuo

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
16. 宮西浩嗣

# of Collaborated Projects : 0results

# of Collaborated Products : 4results
17. 平川昌宏

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
18. 平田公一

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
19. 水口徹

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
20. 岡川泰

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
21. 大須賀崇裕

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
22. 河野豊

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
23. 井山諭

# of Collaborated Projects : 0results

# of Collaborated Products : 2results

TAKADA Koichi 高田 弘一

Research Projects

Research Products

Co-Researchers

細胞の糖代謝特性を利用した新規大腸癌治療法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

酸化ストレスによる多発性骨髄腫病態修飾機序の解析および新規治療法の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of exosomal miRNA on AML/MDS stromal cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identifing novel therapeutic target molecules in multiple myeloma using BCL9-ChIPSeqPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Targeted disruption of the BCL9/beta-catenin complex in colorectal cancer using stapled peptidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌随伴線維芽細胞を標的としたがん治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel anti-fibrotic therapy for scirrhous gastric cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

非アルコール性脂肪性肝炎発症に関わる鉄代謝異常の分子機構解析と治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TGF-βシグナルにお1るプロテインボスフターゼ2Aの癌抑制潰伝子としての意義

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 血液症候群（第２版） 薬剤誘発性赤芽球癆2013

Author(s)

Total Pages

Publisher

Data Source

[Book] 分子生物学が可能とした個別化医療2012

Author(s)

Data Source

[Book] 臨床消化器内科 NASHにおける鉄代謝異常2007

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Ofatumumab combined with chlorambucil for previously untreated chronic lymphocytic leukemia: a phase I/II, open-label study in Japan2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma2017

Author(s)

Journal Title

DOI

TAKADA Koichi 高田弘一

[Book] 血液症候群（第２版）　薬剤誘発性赤芽球癆2013