Takada Kohichi 高田弘一

… Alternative Names

Researcher Number	90398321
Other IDs
Affiliation (Current)	2021: 札幌医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2016 – 2020: 札幌医科大学, 医学部, 講師 2017: 札幌医科大学, 医学部, 助教 2010 – 2015: 札幌医科大学, 医学部, 助教 2008: 札幌医大, 医学部, 助教 2007 – 2008: Sapporo Medical University, 医学部, 助教 2006: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Hematology / Tumor therapeutics / Basic Section 53010:Gastroenterology-related Except Principal Investigator Biological Sciences / Gastroenterology / Hematology / Tumor therapeutics / Basic Section 56020:Orthopedics-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator BCL9 / 多発性骨髄腫 / STEAP1 / 活性酸素種 / NASH / 鉄代謝 / 鉄吸収試験 / Hepcidin / 除鉄療法 / 抗大腸癌ペプチド … More Except Principal Investigator TGF-β / PP2A / p53 / antioncogene / CAF / DDS / targeting / 細胞標的治療 / がん随伴線維芽細胞 / 癌 / 線維化 / 内科 / スキルス胃癌 / 抗線維化 / 抗がん剤 / 治療 / 後線維化 / エクソソーム / マイクロRNA / 白血病 / 骨髄異形成症候群 / 骨髄間質細胞 / PCBP1 / エキソソーム / 間葉系幹細胞 / 骨髄間質 / 白血病幹細胞 / 細胞外小胞 / 大腸癌 / 糖代謝特性 / 神経線維腫1型 / プロテオミクス / プロテアソーム / 難治性軟部肉腫 / 標的抗がん治療法 / AYA世代 Less

ショットガンプロテオミクスを用いた神経線維腫の悪性化機序解明と治療への応用
- Principal Investigator
  
  江森誠人
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Sapporo Medical University
AYA世代難治性軟部肉腫に対する新規標的抗がん治療法の開発
- Principal Investigator
  
  村瀬和幸
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Sapporo Medical University
STEAP1を介した酸化ストレス制御による新規肝細胞癌治療法の開発Principal Investigator
- Principal Investigator
  
  高田弘一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
細胞の糖代謝特性を利用した新規大腸癌治療法の開発
- Principal Investigator
  
  加藤淳二
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
Reactive oxygen species play roles in multiple myeloma pathogenesisPrincipal Investigator
- Principal Investigator
  
  Kohichi Takada
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
The effect of exosomal miRNA on AML/MDS stromal cells
- Principal Investigator
  
  Kobune Masayoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Identifing novel therapeutic target molecules in multiple myeloma using BCL9-ChIPSeqPrincipal Investigator
- Principal Investigator
  
  Takada Kohichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Targeted disruption of the BCL9/beta-catenin complex in colorectal cancer using stapled peptidePrincipal Investigator
- Principal Investigator
  
  TAKADA Kohichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
癌随伴線維芽細胞を標的としたがん治療法の開発
- Principal Investigator
  
  瀧本理修
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
A novel anti-fibrotic therapy for scirrhous gastric cancer.
- Principal Investigator
  
  TAKIMOTO Rishu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
非アルコール性脂肪性肝炎発症に関わる鉄代謝異常の分子機構解析と治療法の開発Principal Investigator
- Principal Investigator
  
  高田弘一
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
TGF-βシグナルにお1るプロテインボスフターゼ2Aの癌抑制潰伝子としての意義
- Principal Investigator
  
  TAKIMOTO Rishu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2007

All Journal Article Presentation Book

[Book] 血液症候群（第２版）　薬剤誘発性赤芽球癆2013
- Author(s)
  高田弘一
- Total Pages
  535
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25461430
[Book] 分子生物学が可能とした個別化医療2012
- Author(s)
  高田弘一
- Data Source
  KAKENHI-PROJECT-23890169
[Book] 臨床消化器内科 NASHにおける鉄代謝異常2007
- Author(s)
  高田弘一
- Total Pages
  6
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-19590780
[Journal Article] FOXO3a Activation by HDAC Class IIa Inhibition Induces Cell Cycle Arrest in Pancreatic Cancer Cells2020
- Author(s)
  Usami Makoto、Kikuchi Shohei、Takada Kohichi、Ono Michihiro、Sugama Yusuke、Arihara Yohei、Hayasaka Naotaka、Nakamura Hajime、Ikeda Yuuki、Hirakawa Masahiro、Yoshida Makoto、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Pancreas
  
  Volume: 49 Pages: 135-142
- DOI
  10.1097/mpa.0000000000001462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08397
[Journal Article] Successful Treatment of Hepatocellular Carcinoma with Transcatheter Arterial Chemoembolization followed by Radical Liver Transplantation in a Patient with Severe Liver Damage2019
- Author(s)
  Nakamura Hajime、Kawano Yutaka、Miyanishi Koji、Ishikawa Kazuma、Kubo Tomohiro、Tanaka Shingo、Takada Kohichi、Kobune Masayoshi、Harada Kohei、Kawamura Norio、Shimamura Tsuyoshi、Kanno-Okada Hiromi、Kato Junji
- Journal Title
  
  Case Reports in Oncology
  
  Volume: 12 Pages: 289-296
- DOI
  10.1159/000499703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08397
[Journal Article] Combination of eribulin plus AKT inhibitor evokes synergistic cytotoxicity in soft tissue sarcoma cells.2019
- Author(s)
  Hayasaka Naotaka、Takada Kohichi、Nakamura Hajime、Arihara Yohei、Kawano Yutaka、Osuga Takahiro、Murase Kazuyuki、Kikuchi Shohei、Iyama Satoshi、Emori Makoto、Sugita Shintaro、Hasegawa Tadashi、Takasawa Akira、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Sci Rep
  
  Volume: 9 Pages: 5759-5759
- DOI
  10.1038/s41598-019-42300-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09112, KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-17K10974
[Journal Article] Six-transmembrane epithelial antigen of the prostate 1 protects against increased oxidative stress via a nuclear erythroid 2-related factor pathway in colorectal cancer2018
- Author(s)
  Nakamura Hajime、Takada Kohichi、Arihara Yohei、Hayasaka Naotaka、Murase Kazuyuki、Iyama Satoshi、Kobune Masayoshi、Miyanishi Koji、Kato Junji
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: -
- DOI
  10.1038/s41417-018-0056-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] High expression of nucleoporin 133 mRNA in bone marrow CD138+ cells is a poor prognostic factor in multiple myeloma2018
- Author(s)
  Ibata Soushi、Kobune Masayoshi、Kikuchi Shohei、Yoshida Masahiro、Miura Shogo、Horiguchi Hiroto、Murase Kazuyuki、Iyama Satoshi、Takada Kohichi、Miyanishi Koji、Kato Junji
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 25127-25135
- DOI
  10.18632/oncotarget.25350
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Increased Duodenal Iron Absorption Through Upregulation of Ferroportin 1 Due to the Decrement in Serum Hepcidin in Patients With Chronic Hepatitis C2018
- Author(s)
  Sato Masanori、Miyanishi Koji、Tanaka Shingo、Sakurada Akira、Sakamoto Hiroki、Kawano Yutaka、Takada Kohichi、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Can J Gastroenterol Hepatol.
  
  Volume: 2018 Pages: 2154361-2154361
- DOI
  10.1155/2018/2154361
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599
[Journal Article] An Intronic Single Nucleotide Polymorphism in the MUTYH Gene Is Associated With Increased Risk for HCV-induced Hepatocellular Carcinoma2018
- Author(s)
  Sakurada Akira、Miyanishi Koji、Tanaka Shingo、Sato Masanori、Sakamoto Hiroki、Kawano Yutaka、Takada Kohichi、Nakabeppu Yusaku、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 129 Pages: 88-96
- DOI
  10.1016/j.freeradbiomed.2018.09.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599
[Journal Article] Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma2017
- Author(s)
  Arihara Yohei、Takada Kohichi、Kamihara Yusuke、Hayasaka Naotaka、Nakamura Hajime、Murase Kazuyuki、Ikeda Hiroshi、Iyama Satoshi、Sato Tsutomu、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 65889-65899
- DOI
  10.18632/oncotarget.19508
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K09482
[Journal Article] Ofatumumab combined with chlorambucil for previously untreated chronic lymphocytic leukemia: a phase I/II, open-label study in Japan2017
- Author(s)
  Hatake Kiyohiko、Ogura Michinori、Takada Kohichi、Taniwaki Masafumi、Zhang Fanghong、Fujita Taizo、Ando Kiyoshi
- Journal Title
  
  Int J Hematol
  
  Volume: 106 Pages: 240-247
- DOI
  10.1007/s12185-017-2233-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] A phase II study of modified docetaxel, cisplatin, and S-1 (mDCS) chemotherapy for unresectable advanced gastric cancer2017
- Author(s)
  Uemura Naoki、Kikuchi Shohei、Sato Yasushi、Ohnuma Hiroyuki、Okamoto Koichi、Miyamoto Hiroshi、Hirakawa Masahiro、Sagawa Tamotsu、Fujikawa Koshi、Takahashi Yasuo、Okuda Toshinori、Minami Shinya、Takahashi Minoru、Okamoto Tetsuro、Takada Kohichi、Miyanisi Koji、Takayama Tetsuji、Kato Junji
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 80 Pages: 707-713
- DOI
  10.1007/s00280-017-3404-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K06857
[Journal Article] Hepatitis C virus reactivation due to antiemetic steroid therapy during treatment of hepatocellular carcinoma2017
- Author(s)
  Kawano Yutaka、Miyanishi Koji、Takahashi Satoshi、Kubo Tomohiro、Ishikawa Kazuma、Sugita Shintaro、Takada Kohichi、Kobune Masayoshi、Hasegawa Tadashi、Kato Junji
- Journal Title
  
  J Infect Chemother
  
  Volume: 23 Pages: 323-325
- DOI
  10.1016/j.jiac.2016.12.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03599
[Journal Article] Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells.2016
- Author(s)
  Okagawa Y, Murase K, Kato J, et al
- Journal Title
  
  PLoS One
  
  Volume: 15
- DOI
  10.1371/journal.pone.0168355
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
[Journal Article] Narrow-Band Ultraviolet B Phototherapy Ameliorates Acute Graft-Versus-Host Disease of the Intestine by Expansion of Regulatory T Cells2016
- Author(s)
  Hashimoto A, Murase K, Kato J. et al
- Journal Title
  
  PLoS One
  
  Volume: 31
- DOI
  10.1371/journal.pone.0152823
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461429, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26670178, KAKENHI-PROJECT-26670386
[Journal Article] The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.2016
- Author(s)
  Kamihara Y, Murase K, Kato J, et al
- Journal Title
  
  Oncotarget.
  
  Volume: 27 Pages: 64330-64341
- DOI
  10.18632/oncotarget.11830
- NAID
  120006576953
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
[Journal Article] Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms.2016
- Author(s)
  Horiguchi H, Murase K, Kato J. et al
- Journal Title
  
  Haematologica
  
  Volume: 101 Pages: 437-447
- DOI
  10.3324/haematol.2015.134932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26670386
[Journal Article] A phase II trial of small-dose bortezomib, lenalidomide and dexamethasone (sVRD) as consolidation/maintenance therapy in patients with multiple myeloma.2016
- Author(s)
  Ibata S, Sato T, Kuroda H, Nagamachi Y, Iyama S, Fujimi A, Kamihara Y, Konuma Y, Yoshida M, Tatekoshi A, Hashimoto A, Horiguchi H, Ono K, Murase K, Takada K, Miyanishi K, Kobune M, Hirayama Y, Kato J.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 78 Pages: 1041-1049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Effect of duloxetine in Japanese patients with chemotherapy-induced peripheral neuropathy: a pilot randomized trial2015
- Author(s)
  Hirayama Y, Takada K, Kato J, et al
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] 10. Increased duodenal iron absorption through up-regulation of divalent metal transporter 1 from enhancement of iron regulatory protein 1 activity in patients with nonalcoholic steatohepatitis.2015
- Author(s)
  Hoki T, Miyanishi K, Kato J, et al.
- Journal Title
  
  Hematology
  
  Volume: 印刷中 Pages: 751-61
- DOI
  10.1002/hep.27774
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591027, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09013, KAKENHI-PROJECT-15K09482, KAKENHI-PROJECT-25461430
[Journal Article] Effect of duloxetine in Japanese patients with chemotherapy-induced peripheral neuropathy: a pilot randomized trial.2015
- Author(s)
  Hirayama Y, Ishitani K, Sato Y, Iyama S, Takada K, Murase K, Kuroda H, Nagamachi Y, Konuma Y, Fujimi A, Sagawa T, Ono K, Horiguchi H, Terui T, Koike K, Kusakabe T, Sato T, Takimoto R, Kobune M, Kato J
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 20 Pages: 866-71
- DOI
  10.1007/s10147-015-0810-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09482, KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430
[Journal Article] BAK is a predictive and prognostic biomarker for the therapeutic effect of docetaxel treatment in patients with advanced gastric cancer.2015
- Author(s)
  Kubo T, Takada K, Kato J, et al
- Journal Title
  
  Gastric Cancer
  
  Volume: 0 Pages: 0-0
- NAID
  40020881713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A dose-escalation study of oxaliplatin/capecitabine/irinotecan (XELOXIRI) and bevacizumab as a first-line therapy for patients with metastatic colorectal cancer.2015
- Author(s)
  Sato Y, Ohnuma H, Hirakawa M, Takahashi M, Osuga T, Okagawa Y, Murase K, Takada K, Kawano Y, Iyama S, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Okita K, Mizuguchi T, Furuhata T, Hirata K, Kato J
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 75 Pages: 587-594
- DOI
  10.1007/s00280-014-2672-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09508
[Journal Article] Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer2014
- Author(s)
  Hashimoto A, Takada K, Kato J, et al
- Journal Title
  
  Case Rep Oncol
  
  Volume: 17 Pages: 316-22
- DOI
  10.1159/000363100
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Radiation-induced leiomyosarcoma of the prostate after brachytherapy for prostatic adenocarcinoma2014
- Author(s)
  Horiguchi H, Takada K, Kato J, et al
- Journal Title
  
  Case Rep Oncol
  
  Volume: 16 Pages: 565-70
- DOI
  10.1159/000366294
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Anti-erythropoietin receptor antibody-associated pure red cell aplasia accompanied by Coombs-negative autoimmune hemolytic anemia in a patient with T cell/histiocyte-rich large B cell lymphoma2014
- Author(s)
  Fujimi A, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 100 Pages: 490-3
- DOI
  10.1007/s12185-014-1652-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway2014
- Author(s)
  Zhao JJ, Takada K, Carrasco R, et al
- Journal Title
  
  Cancer Research
  
  Volume: 15 Pages: 1801-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] リツキシマブが奏効した難治性の混合式自己免疫性溶血性貧血2014
- Author(s)
  小野薫，高田弘一，加藤淳二，他
- Journal Title
  
  臨床血液
  
  Volume: 54 Pages: 2053-5
- NAID
  130004920528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A role for peripherally inserted central venous catheters in the prevention of catheter-related blood stream infections in patients with hematological malignancies2014
- Author(s)
  Sakai T, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 100 Pages: 592-8
- DOI
  10.1007/s12185-014-1677-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Pazopanibが有効であった転移性横紋筋肉腫の一例2014
- Author(s)
  橋本亜香利，高田弘一，加藤淳二，他
- Journal Title
  
  癌と化学療法
  
  Volume: 0 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Successful Treatment with Entecavir for Reactivation of Hepatitis B Virus Following Systemic Chemotherapy in a Hepatitis B Surface Antigen-negative Patient with Colorectal Cancer2014
- Author(s)
  Okagawa Y, Takada K, Kato J, et al
- Journal Title
  
  Internal Medicine
  
  Volume: 0 Pages: 0-0
- NAID
  130004678403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Efficacy of Enteral Supplementation Enriched with Glutamine, Fiber, and Oligosaccharide on Mucosal Injury following Hematopoietic Stem Cell Transplantation2014
- Author(s)
  Iyama S, Sato T, Tatsumi H, Hashimoto A, Tatekoshi A, Kamihara Y, Horiguchi H, Ibata S, Ono K, Murase K, Takada K, Sato Y, Hayashi T, Miyanishi K, Akizuki E, Nobuoka T, Mizuguchi T, Takimoto R, Kobune M, Hirata K, Kato J.
- Journal Title
  
  Case Rep Oncol
  
  Volume: 7 Pages: 692-699
- DOI
  10.1159/000368714
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591427, KAKENHI-PROJECT-25461430
[Journal Article] A novel strategy inducing autophagic cell death in Burkitt's lymphoma cells with anti-CD19-targeted liposomal rapamycin2014
- Author(s)
  Ono K, Takada K, Kato J, et al
- Journal Title
  
  Blood Cancer J
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells2014
- Author(s)
  Tamura F, Takada K, Kato J, et al
- Journal Title
  
  Gastric Cancer
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Narrowband ultraviolet B phototherapy ameliorates acute graft-versus-host disease by a mechanism involving in vivo expansion of CD4+CD25+Foxp3+ regulatory T cells2014
- Author(s)
  Iyama S, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 0 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] TRIM13(RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NFKappa B pathway and proteasome activity2013
- Author(s)
  Gatt ME, Takada K, Carrasco DR, et al
- Journal Title
  
  Br J Haematol
  
  Volume: 162 Pages: 21-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A case of idiopathic encapsulating peritoneal sclerosis with intractable ileus successfully treated by surgery and steroid therapy2013
- Author(s)
  Ikeda Y, Takada K, Kato J, et al
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 6 Pages: 295-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker.2013
- Author(s)
  Hirakawa M, Sato Y, Ohnuma H, Takayama T, Sagawa T, Nobuoka T, Harada K, Miyamoto H, Sato Y, Takahashi Y, Katsuki S, Hirayama M, Takahashi M, Ono M, Maeda M, Takada K, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Hirata K, Kato J
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 71 Pages: 789-797
- DOI
  10.1007/s00280-013-2073-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24659372
[Journal Article] A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker2013
- Author(s)
  Hirakawa M, Takada K, Kato J, et al
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 71 Pages: 789-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] TRIM13(RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NFKappa B pathway and proteasome activity.2013
- Author(s)
  Gatt ME, Takada K, Mani M, Lerner M, Pick M, Hideshima T, Carrasco DE, Protopopov A, Ivanova E, Sangfelt O, Grander D, Barlogie B, Shaughessy JD Jr, Anderson KC, Carrasco DR
- Journal Title
  
  Br J Haematol
- DOI
  10.1111/bjh.12365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Fucosylated TGF-β receptors transduces a signal for epithelial-mesenchymal transition in colorectal cancer cells2013
- Author(s)
  Hirakawa M, Takada K, Kato J, et al
- Journal Title
  
  Br J Cancer
  
  Volume: 110 Pages: 156-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Targeted Disruption of the BCL9/・-catenin Complex Inhibits Oncogenic Wnt Signaling.2012
- Author(s)
  Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulcinti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR
- Journal Title
  
  Sci Transl Med
  
  Volume: 4(148) Pages: 148-117
- DOI
  10.1126/scitranslmed.3003808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Diagnostic validity of CT gastrography versus gastroscopy for primary lesions in gastric cancer: evaluating the response to chemotherapy, a retrospective analysis.2012
- Author(s)
  Takahashi S, Hirayama M, Kuroiwa G, Kawano Y, Takada K, Sato T, Miyanishi K, Sato Y, Takimoto R, Kobune M, Kato J.
- Journal Title
  
  Gatric Cancer
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] 10. Targeting anticancer drug delivery to pancreatic cancer cells using a fucose-bound nanoparticle approach.2012
- Author(s)
  Yoshida M, Takimoto R, Murase K, Sato Y, Hirakawa M, Tamura F, Sato T, Iyama S, Osuga T, Miyanishi K, Takada K, Hayashi T, Kobune M, Kato J.
- Journal Title
  
  PLoS One.
  
  Volume: 7(7)
- DOI
  10.1371/journal.pone.0039545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590921, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-24659372
[Journal Article] Prognostic significance of serum ferritin level at diagnosis in myelodysplastic syndrome.2012
- Author(s)
  Kobune M, et al. 2^<nd>
- Journal Title
  
  Int J Hematol
  
  Volume: (In press) Pages: 527-534
- DOI
  10.1007/s12185-012-1048-3
- NAID
  10030633185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24659372, KAKENHI-PROJECT-24659466
[Journal Article] Intermittent administration of recombinant human soluble thrombomodulin successfully controlled chronic disseminated intravascular coagulation in a patient with dissecting aortic aneurysm on an outpatients basis.2012
- Author(s)
  Iyama S, Sato T, et al.
- Journal Title
  
  Blood Coagul Fibrinolysis
  
  Volume: 23 Pages: 548-50
- DOI
  10.1097/mbc.0b013e32835510d6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591043, KAKENHI-PROJECT-23890169
[Journal Article] Improvement of iron-mediated oxidative DNA damage in patients with transfusion-dependent myelodysplastic syndrome by treatment with deferasirox2012
- Author(s)
  Kikuchi S, Kobune M, Iyama S, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kaneko Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 23(6) Pages: 548-550
- DOI
  10.1016/j.freeradbiomed.2012.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24659466
[Journal Article] Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms.2012
- Author(s)
  Kobune M, Iyama S, Kikuchi S, Horiguchi H, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kamihara Y, Hayashi T, Miyanishi K, Sato Y, Takimoto R, Kato J.
- Journal Title
  
  Blood Cancer J
- DOI
  10.1038/bcj.2012.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Successful treatment bu fibrin glue sealant for pneumothorax with chronic GVHD resistant to autologous blood patch pleurodesis.2012
- Author(s)
  Iyama S, Sato T, Murase K, Kikuchi S, Kamihara Y, Ono K, Takada K, Miyanishi K, Sato Y, Takimoto R, Kobune M, Obama T, Miyajima M, Watanabe A, Higami T, Hirayama Y, Kato J.
- Journal Title
  
  Intern Med
  
  Volume: 51(15) Pages: 2011-2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Prognostic significance of serum ferritin level at diagnosis in myelodysplastic syndrome2012
- Author(s)
  Kikuchi S, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] catenin is dramatically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway.2012
- Author(s)
  Sukhdeo K, Mani M, Hideshima T, Takada K, Pena-Cruz V, Mendez G, Ito S, Anderson KC, Carrasco DR
- Journal Title
  
  Leukemia
  
  Volume: 26(5) Pages: 1116-1119
- DOI
  10.1038/leu.2011.303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] UGT1A1*28 and *6polymorphisms and nilotinib-induced unconjugated hyperbilirubinemia in a Japanese patient with chronic myelogenous leukemia.2012
- Author(s)
  Takada K, Sato T, Iyama S, Ono K, Kamihara Y, Murase K, Kawano Y, Hayashi T, Miyanishi K, Sato Y, Kobune M, Takimoto R, Kato J
- Journal Title
  
  Int Canc Conf J201
  
  Volume: 1 Pages: 220-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Pages: 715-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Novel missense mutation in the TMPRSS6 gene in a Japanese female with iron-refractory deficiency anemia2011
- Author(s)
  Sato T, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Pages: 101-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Iron chelator deferasirox rescued mice from Fas-induced fulminant hepatitis2011
- Author(s)
  Sato T, Takada K, Kato J, et al
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M, Takimoto R, Kato, J
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Pages: 715-719
- DOI
  10.1007/s12185-011-0878-8
- NAID
  10029535427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231, KAKENHI-PROJECT-23890169
[Journal Article] b-catenin is dramatically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway2011
- Author(s)
  Suhhdeo K, Takada K, Carrasco DR, et al
- Journal Title
  
  Leukemia
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Novel missense mutation in the TMPRSS6 gene in Japanese female with iron-refractory deficiency anemia2011
- Author(s)
  Sato T, Takimoto R, Kato J
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Pages: 101-103
- DOI
  10.1007/s12185-011-0881-0
- NAID
  10029536603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231, KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-22591043, KAKENHI-PROJECT-23890169
[Presentation] Extravesicular Mir-7977 Released from Leukemic Cells Inhibites the PCBP1-Mediated mRNA Stabilization and Hippo-YAP Signaling Pathway in Bone Marrow Mesenchymal Stromal Cells.2018
- Author(s)
  Masahiro Yoshida, Kohichi Takada
- Organizer
  ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Presentation] Combination of eribulin plus Akt inhibitor evokes synergistic cytotoxicity in soft tissue sarcoma cells.2018
- Author(s)
  Kohichi Takada
- Organizer
  Annual Meeting of the American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Presentation] p53-restoring small molecule CP-31398 induced apoptosis via induction of reactive oxidative species in human multiple myeloma2017
- Author(s)
  Yohei Arihara, Kohichi Takada
- Organizer
  European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Presentation] Exosomal microRNAs in bone marrow cavity induce stromal dysfunction in AML/MDS2015
- Author(s)
  Hiroto Horiguchi, Masayoshi Kobune, Shohei Kikuchi, Kazuyuki Murase, Satoshi Iyama, Kohichi Takada, Tsutomu Sato, Yasushi Sato1), Koji Miyanishi1), Rishu Takimoto, Hiroyuki Kuroda, Masahiro Maeda, Junji Kato
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県金沢市ホテル日航金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K09482
[Presentation] BCL9/beta-catenin 転写複合体を標的とした新規大腸癌治療法の開発2012
- Author(s)
  高田弘一
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] BCL9/β-catenin 転写複合体を標的とした新規大腸癌治療法の開発2012
- Author(s)
  高田弘一
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] BCL9は大腸癌および多発性骨髄腫において細胞増殖,浸潤・転移能および腫瘍血管新生を亢進させる2011
- Author(s)
  高田弘一, 加藤淳二, Carrasco DR
- Organizer
  第91回北海道医学大会腫瘍系分科会
- Place of Presentation
  札幌医科大学
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] 非アルコール性脂肪性肝炎における鉄代謝異常の分子機構解析2007
- Author(s)
  高田弘一
- Organizer
  第49回日本消化器病学会大会
- Place of Presentation
  神戸
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19590780

1. KATO JUNJI (20244345)

# of Collaborated Projects: 7 results

# of Collaborated Products: 40 results
2. TAKIMOTO Rishu (10336399)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
3. SATO Yasushi (80343383)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. KOBUNE MASAYOSHI (90336389)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. 村瀬和幸 (90444918)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. 宮西浩嗣 (60372819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
7. KAMIHARA YUSUKE (10624421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 佐藤勉 (40404602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. 堀口拓人 (70634674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 在原洋平 (30749586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 早坂尚貴 (00792665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大須賀崇裕 (40619714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 江森誠人 (20580286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 高澤啓 (00593021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 村橋靖崇 (90855842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 中村元 (10792666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HAYASHI Tsuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. KIKUCHI Shohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. IYAMA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. HIMI Tetsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 平川昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 河野豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 一宮慎吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 佐藤昇志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 水口徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 平田公一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 岡川泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takada Kohichi 高田 弘一

TAKADA Koichi 高田 弘一

高田 弘一 タカダ コウイチ

Research Projects

Research Products

Co-Researchers

ショットガンプロテオミクスを用いた神経線維腫の悪性化機序解明と治療への応用

Principal Investigator

Project Period (FY)

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AYA世代難治性軟部肉腫に対する新規標的抗がん治療法の開発

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

STEAP1を介した酸化ストレス制御による新規肝細胞癌治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

細胞の糖代謝特性を利用した新規大腸癌治療法の開発

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Reactive oxygen species play roles in multiple myeloma pathogenesisPrincipal Investigator

Principal Investigator

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Research Institution

The effect of exosomal miRNA on AML/MDS stromal cells

Principal Investigator

Project Period (FY)

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Identifing novel therapeutic target molecules in multiple myeloma using BCL9-ChIPSeqPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Targeted disruption of the BCL9/beta-catenin complex in colorectal cancer using stapled peptidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌随伴線維芽細胞を標的としたがん治療法の開発

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

A novel anti-fibrotic therapy for scirrhous gastric cancer.

Principal Investigator

Project Period (FY)

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Research Institution

非アルコール性脂肪性肝炎発症に関わる鉄代謝異常の分子機構解析と治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

TGF-βシグナルにお1るプロテインボスフターゼ2Aの癌抑制潰伝子としての意義

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

[Book] 血液症候群（第２版） 薬剤誘発性赤芽球癆2013

Author(s)

Takada Kohichi 高田弘一

TAKADA Koichi 高田弘一

高田弘一タカダコウイチ

[Book] 血液症候群（第２版）　薬剤誘発性赤芽球癆2013