Takada Kohichi 高田弘一

… Alternative Names

TAKADA Koichi 高田弘一

高田弘一タカダコウイチ

Less

Researcher Number	90398321
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 札幌医科大学, 医学部, 講師 2017: 札幌医科大学, 医学部, 助教 2010 – 2015: 札幌医科大学, 医学部, 助教 2008: 札幌医大, 医学部, 助教 2007 – 2008: Sapporo Medical University, 医学部, 助教 2006: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Tumor therapeutics / Hematology Except Principal Investigator Basic Section 56020:Orthopedics-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Biological Sciences / Basic Section 59040:Nutrition science and health science-related / Basic Section 53010:Gastroenterology-related / Tumor therapeutics / Hematology / Gastroenterology
Keywords	Principal Investigator HCC / 活性酸素種 / STEAP1 / 多発性骨髄腫 / BCL9 / Immunotherapy / BRG1 / 肝細胞癌 / c-Myc / NRF2 … More / 酸化ストレス / 骨髄ホーミング / 浸潤 / 転移 / Wntシグナル / Wnt シグナル / 抗大腸癌ペプチド / 除鉄療法 / Hepcidin / 鉄吸収試験 / 鉄代謝 / NASH … More Except Principal Investigator プロテオミクス / ショットガンプロテオーム / プロテオーム解析 / 標的抗がん治療法 / 標的抗がん治療法 / 難治性軟部肉腫 / 腸管機能モニタリング / 栄養療法 / 腸管粘膜障害 / がん化学療法 / 腸内細菌叢 / ジアミンオキシダーゼ / 肺転移 / 骨肉腫 / 感受性予測 / 耐性機構 / miRNA / 効果予測因子 / 化学放射線療法 / 食道癌 / 脱分化 / 軟骨肉腫 / 免疫原性細胞死 / 神経線維腫1型 / 肉腫 / プロテアソーム / プロテオーム / 悪性末梢神経鞘腫瘍 / 神経線維腫 / 軟部肉腫 / AYA世代 / 糖代謝特性 / ドラッグデリバリー / ドラッグデリバリーシステム / 大腸癌 / 細胞外小胞 / 白血病幹細胞 / 骨髄間質 / 間葉系幹細胞 / エキソソーム / PCBP1 / 骨髄間質細胞 / 骨髄異形成症候群 / 白血病 / マイクロRNA / エクソソーム / 後線維化 / 治療 / 抗がん剤 / 抗線維化 / スキルス胃癌 / 内科 / 線維化 / 癌 / がん随伴線維芽細胞 / 細胞標的治療 / targeting / DDS / CAF / antioncogene / p53 / PP2A / TGF-β Less

Establishment of new treatment method for dedifferentiated chondrosarcoma
- Principal Investigator
  
  清水淳也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Sapporo Medical University
Analyzing and overcoming chemoradiation resistance mechanism for esophageal squamous cell carcinoma through miRNA functional analysis
- Principal Investigator
  
  大沼啓之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
プロテオーム解析による骨肉腫の肺転移機序解明と新規治療開発
- Principal Investigator
  
  江森誠人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Sapporo Medical University
がん化学療法時の栄養状態に関わる腸管機能モニタリングの確立
- Principal Investigator
  
  井山諭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Sapporo Medical University
AYA世代難治性軟部肉腫に対する免疫原性細胞死を利用した新規抗がん治療法の開発
- Principal Investigator
  
  村瀬和幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Sapporo Medical University
Development a novel immnunotherapy for hepatocellular carcinoma targeted by BRG1Principal Investigator
- Principal Investigator
  
  高田弘一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
To elucidate the mechanisms of developing malignant peripheral nerve sheath tumor in neurofibroma using shut-gun proteome analysis
- Principal Investigator
  
  Emori Makoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Sapporo Medical University
Development of a new targeted anticancer treatment for Adolescent and Young Adult refractory soft tissue sarcoma
- Principal Investigator
  
  Murase Kazuyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Sapporo Medical University
Development a novel therapy for hepatocellular carcinoma by targeting STEAP1Principal Investigator
- Principal Investigator
  
  Takada Kohichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Development of a new treatment for colorectal cancer using the glucose metabolism characteristics.
- Principal Investigator
  
  Kato Junji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
Reactive oxygen species play roles in multiple myeloma pathogenesisPrincipal Investigator
- Principal Investigator
  
  Kohichi Takada
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
The effect of exosomal miRNA on AML/MDS stromal cells
- Principal Investigator
  
  Kobune Masayoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Identifing novel therapeutic target molecules in multiple myeloma using BCL9-ChIPSeqPrincipal Investigator
- Principal Investigator
  
  Takada Kohichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Targeted disruption of the BCL9/beta-catenin complex in colorectal cancer using stapled peptidePrincipal Investigator
- Principal Investigator
  
  TAKADA Kohichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
癌随伴線維芽細胞を標的としたがん治療法の開発
- Principal Investigator
  
  瀧本理修
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
A novel anti-fibrotic therapy for scirrhous gastric cancer.
- Principal Investigator
  
  TAKIMOTO Rishu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
非アルコール性脂肪性肝炎発症に関わる鉄代謝異常の分子機構解析と治療法の開発Principal Investigator
- Principal Investigator
  
  高田弘一
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
TGF-βシグナルにお1るプロテインボスフターゼ2Aの癌抑制潰伝子としての意義
- Principal Investigator
  
  TAKIMOTO Rishu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University

[Book] 血液症候群（第２版）　薬剤誘発性赤芽球癆2013
- Author(s)
  高田弘一
- Total Pages
  535
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25461430
[Book] 分子生物学が可能とした個別化医療2012
- Author(s)
  高田弘一
- Data Source
  KAKENHI-PROJECT-23890169
[Book] 臨床消化器内科 NASHにおける鉄代謝異常2007
- Author(s)
  高田弘一
- Total Pages
  6
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-19590780
[Journal Article] Gap junction beta‐4 accelerates cell cycle progression and metastasis through MET?AKT activation in pancreatic cancer2024
- Author(s)
  Muramatsu Joji、Arihara Yohei、Yoshida Makoto、Kubo Tomohiro、Nakamura Hajime、Ishikawa Kazuma、Fujita Hiromi、Sugita Shintaro、Konno Takumi、Kojima Takashi、Kawano Yutaka、Kobune Masayoshi、Takada Kohichi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 1564-1575
- DOI
  10.1111/cas.16101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-22K08509
[Journal Article] ST2825, independent of MyD88, induces reactive oxygen species-dependent apoptosis in multiple myeloma cells2024
- Author(s)
  Nakamura Hajime、Arihara Yohei、Usami Makoto、Takada Kohichi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 38 Pages: 101681-101681
- DOI
  10.1016/j.bbrep.2024.101681
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080
[Journal Article] Simultaneous XIAP and cIAP1/2 inhibition by a dimeric SMAC mimetic AZD5582 induces apoptosis in multiple myeloma2024
- Author(s)
  Kikuchi Shohei、Sugama Yusuke、Takada Kohichi、Kamihara Yusuke、Wada Akinori、Arihara Yohei、Nakamura Hajime、Sato Tsutomu
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 1 Pages: 30-36
- DOI
  10.1016/j.jphs.2023.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080
[Journal Article] Physical Properties and Cellular Metabolic Characteristics of 3D Spheroids Are Possible Definitive Indices for the Biological Nature of Cancer-Associated Fibroblasts2023
- Author(s)
  Nishikiori Nami、Takada Kohichi、Sato Tatsuya、Miyamoto Sho、Watanabe Megumi、Hirakawa Yui、Sekiguchi Shohei、Furuhashi Masato、Yorozu Akira、Takano Kenichi、Miyazaki Akihiro、Suzuki Hiromu、Ohguro Hiroshi
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 17 Pages: 2160-2160
- DOI
  10.3390/cells12172160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-23K24186, KAKENHI-PROJECT-23K27794
[Journal Article] Coefficient of variation of T2-weighted MRI may predict the prognosis of malignant peripheral nerve sheath tumor2023
- Author(s)
  Emori M, Tsuchie H, Takashima H, Teramoto A, Murahashi Y, Imura Y, Outani H, Nakai S, Takenaka S, Hirota R, Nakahashi N, Shimizu J, Murase K, Takasawa A, Nagasawa H, Sugita S, Takada K, Hasegawa T, Okada S, Miyakoshi N, Yamashita T.
- Journal Title
  
  Skeletal Radiology
  
  Volume: 53 Issue: 4 Pages: 657-664
- DOI
  10.1007/s00256-023-04457-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08657
[Journal Article] Synergistic antitumor effect of histone deacetylase class IIa inhibitor with lenvatinib in hepatocellular carcinoma2023
- Author(s)
  Ito Ryo、Miyanishi Koji、Kubo Tomohiro、Hamaguchi Kota、Osuga Takahiro、Tanaka Shingo、Ohnuma Hiroyuki、Murase Kazuyuki、Takada Kohichi、Nagayama Minoru、Kimura Yasutoshi、Mizuguchi Toru、Takemasa Ichiro、Kato Junji
- Journal Title
  
  Hepatology International
  
  Volume: - Issue: 3 Pages: 735-744
- DOI
  10.1007/s12072-023-10484-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08011, KAKENHI-PROJECT-22K08080
[Journal Article] Establishment and characterization of a novel dedifferentiated chondrosarcoma cell line, SMU-DDCS, harboring an IDH1 mutation2023
- Author(s)
  Emori Makoto、Nakahashi Naoya、Takasawa Akira、Murata Kenji、Murahashi Yasutaka、Shimizu Junya、Tsukahara Tomohide、Sugita Shintaro、Takada Kohichi、Hasegawa Tadashi、Osanai Makoto、Iba Kosuke
- Journal Title
  
  Human Cell
  
  Volume: 36 Issue: 6 Pages: 2195-2203
- DOI
  10.1007/s13577-023-00944-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-23K06445
[Journal Article] A phase 1 trial of <scp>NY‐ESO</scp> ‐1‐specific <scp>TCR</scp> ‐engineered T‐cell therapy combined with a lymph node‐targeting nanoparticulate peptide vaccine for the treatment of advanced soft tissue sarcoma2023
- Author(s)
  Ishihara Mikiya、Nishida Yoshihiro、Kitano Shigehisa、Kawai Akira、Takada Kohichi、Emori Makoto、Kageyama Shinichi、Shiku Hiroshi
- Journal Title
  
  International Journal of Cancer
  
  Volume: 152 Issue: 12 Pages: 2554-2566
- DOI
  10.1002/ijc.34453
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-21H02995, KAKENHI-PROJECT-20K16411, KAKENHI-PROJECT-21K19561, KAKENHI-PROJECT-21K06690, KAKENHI-PROJECT-23K08700, KAKENHI-PROJECT-21K08682, KAKENHI-PROJECT-22K07277, KAKENHI-PROJECT-23K24180
[Journal Article] Effect of comprehensive cancer genomic profiling on therapeutic strategies and clinical outcomes in patients with advanced biliary tract cancer: A prospective multicenter study2022
- Author(s)
  Takada Kohichi、Kubo Tomohiro、Kikuchi Junko
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 12 Pages: 99-99
- DOI
  10.3389/fonc.2022.988527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-22KK0125, KAKENHI-PROJECT-20H03655, KAKENHI-PROJECT-20K07691
[Journal Article] Chimeric antigen receptor T-cell therapy targeting a MAGE A4 peptide and HLA-A*02:01 complex for unresectable advanced or recurrent solid cancer: protocol for a multi-institutional phase 1 clinical trial2022
- Author(s)
  Satoshi Okumura, Mikiya Ishihara, Naomi Kiyota, Kimikazu Yakushijin, Kohichi Takada, Shinichiro Kobayashi, Hiroaki Ikeda, Makoto Endo, Koji Kato, Shigehisa Kitano, Akihiko Matsumine, Yasuhiro Nagata,...Hiroshi Shiku
- Journal Title
  
  BMJ Open
  
  Volume: 12(11) Issue: 11 Pages: e065109-e065109
- DOI
  10.1136/bmjopen-2022-065109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06690, KAKENHI-PROJECT-21K08682, KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-22K08876, KAKENHI-PROJECT-22K19532, KAKENHI-PROJECT-21K16400, KAKENHI-PROJECT-21H02990, KAKENHI-PROJECT-20K09731, KAKENHI-PROJECT-23K24456, KAKENHI-PROJECT-23K24180
[Journal Article] Association between hepatic oxidative stress related factors and activation of Wnt/β-catenin signaling in NAFLD-induced hepatocellular carcinoma.2022
- Author(s)
  Hamaguchi K, Miyanishi K, Osuga T, Tanaka S, Ito R, Sakamoto H, Kubo T, Ohnuma H, Murase K, Takada K, Nagayama M, Kimura Y, Mizuguchi T, Takemasa I, Kato J.
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 9 Pages: 2066-2066
- DOI
  10.3390/cancers14092066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10404, KAKENHI-PROJECT-21K08011, KAKENHI-PROJECT-22K08080
[Journal Article] MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model2021
- Author(s)
  Sakamoto Hiroki、Miyanishi Koji、Tanaka Shingo、Ito Ryo、Hamaguchi Kota、Sakurada Akira、Sato Masanori、Kubo Tomohiro、Osuga Takahiro、Murase Kazuyuki、Takada Kohichi、Nakabeppu Yusaku、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-83138-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-19K08871, KAKENHI-PROJECT-19K17405, KAKENHI-PROJECT-21K08011
[Journal Article] Clinical significance of comprehensive genomic profiling tests covered by public insurance in patients with advanced solid cancers in Hokkaido, Japan2021
- Author(s)
  Kikuchi Junko、Ohhara Yoshihito、Takada Kohichi、Kinoshita Ichiro
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: - Issue: 5 Pages: 753-761
- DOI
  10.1093/jjco/hyaa277
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-20K07691, KAKENHI-PROJECT-19K09818
[Journal Article] Six-transmembrane epithelial antigen of the prostate 1 accelerates cell proliferation by targeting c-Myc in liver cancer cells2021
- Author(s)
  Iijima Kazutaka、Nakamura Hajime、Takada Kohichi、Hayasaka Naotaka、Kubo Tomohiro、Umeyama Yui、Iyama Satoshi、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Oncology Letters
  
  Volume: 22 Issue: 1 Pages: 546-546
- DOI
  10.3892/ol.2021.12807
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-19K08871
[Journal Article] Reactive oxygen species in cancer: Current findings and future directions2021
- Author(s)
  Nakamura Hajime、Takada Kohichi
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 10 Pages: 3945-3952
- DOI
  10.1111/cas.15068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08397
[Journal Article] A systemic apolipoprotein A-IV-associated amyloidosis confirmed by proteome analysis2021
- Author(s)
  Murakami Taro、Takasawa Akira、Moriki Asako、Igaki Yusuke、Ikeda Hiroshi、Murase Kazuyuki、Takada Kohichi、Magara Kazufumi、Aoyama Tomoyuki、Ono Yusuke、Kyuno Daisuke、Takasawa Kumi、Murata Masaki、Osanai Makoto
- Journal Title
  
  Virchows Archiv
  
  Volume: - Issue: 5 Pages: 1041-1046
- DOI
  10.1007/s00428-021-03073-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-21K06890, KAKENHI-PROJECT-20K16196
[Journal Article] FOXO3a Activation by HDAC Class IIa Inhibition Induces Cell Cycle Arrest in Pancreatic Cancer Cells2020
- Author(s)
  Usami Makoto、Kikuchi Shohei、Takada Kohichi、Ono Michihiro、Sugama Yusuke、Arihara Yohei、Hayasaka Naotaka、Nakamura Hajime、Ikeda Yuuki、Hirakawa Masahiro、Yoshida Makoto、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Pancreas
  
  Volume: 49 Issue: 1 Pages: 135-142
- DOI
  10.1097/mpa.0000000000001462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08397
[Journal Article] Successful Treatment of Hepatocellular Carcinoma with Transcatheter Arterial Chemoembolization followed by Radical Liver Transplantation in a Patient with Severe Liver Damage2019
- Author(s)
  Nakamura Hajime、Kawano Yutaka、Miyanishi Koji、Ishikawa Kazuma、Kubo Tomohiro、Tanaka Shingo、Takada Kohichi、Kobune Masayoshi、Harada Kohei、Kawamura Norio、Shimamura Tsuyoshi、Kanno-Okada Hiromi、Kato Junji
- Journal Title
  
  Case Reports in Oncology
  
  Volume: 12 Issue: 1 Pages: 289-296
- DOI
  10.1159/000499703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08397
[Journal Article] Combination of eribulin plus AKT inhibitor evokes synergistic cytotoxicity in soft tissue sarcoma cells2019
- Author(s)
  Hayasaka Naotaka、Takada Kohichi、Nakamura Hajime、Arihara Yohei、Kawano Yutaka、Osuga Takahiro、Murase Kazuyuki、Kikuchi Shohei、Iyama Satoshi、Emori Makoto、Sugita Shintaro、Hasegawa Tadashi、Takasawa Akira、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 5759-5759
- DOI
  10.1038/s41598-019-42300-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09112, KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-17K10974
[Journal Article] High expression of nucleoporin 133 mRNA in bone marrow CD138+ cells is a poor prognostic factor in multiple myeloma2018
- Author(s)
  Ibata Soushi、Kobune Masayoshi、Kikuchi Shohei、Yoshida Masahiro、Miura Shogo、Horiguchi Hiroto、Murase Kazuyuki、Iyama Satoshi、Takada Kohichi、Miyanishi Koji、Kato Junji
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 38 Pages: 25127-25135
- DOI
  10.18632/oncotarget.25350
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Six-transmembrane epithelial antigen of the prostate 1 protects against increased oxidative stress via a nuclear erythroid 2-related factor pathway in colorectal cancer2018
- Author(s)
  Nakamura Hajime、Takada Kohichi、Arihara Yohei、Hayasaka Naotaka、Murase Kazuyuki、Iyama Satoshi、Kobune Masayoshi、Miyanishi Koji、Kato Junji
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: - Issue: 9-10 Pages: 313-322
- DOI
  10.1038/s41417-018-0056-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Increased Duodenal Iron Absorption through Upregulation of Ferroportin 1 due to the Decrement in Serum Hepcidin in Patients with Chronic Hepatitis C2018
- Author(s)
  Sato Masanori、Miyanishi Koji、Tanaka Shingo、Sakurada Akira、Sakamoto Hiroki、Kawano Yutaka、Takada Kohichi、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Canadian Journal of Gastroenterology and Hepatology
  
  Volume: 2018 Pages: 1-9
- DOI
  10.1155/2018/2154361
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599
[Journal Article] An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma2018
- Author(s)
  Sakurada Akira、Miyanishi Koji、Tanaka Shingo、Sato Masanori、Sakamoto Hiroki、Kawano Yutaka、Takada Kohichi、Nakabeppu Yusaku、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 129 Pages: 88-96
- DOI
  10.1016/j.freeradbiomed.2018.09.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599
[Journal Article] A phase II study of modified docetaxel, cisplatin, and S-1 (mDCS) chemotherapy for unresectable advanced gastric cancer2017
- Author(s)
  Uemura Naoki、Kikuchi Shohei、Sato Yasushi、Ohnuma Hiroyuki、Okamoto Koichi、Miyamoto Hiroshi、Hirakawa Masahiro、Sagawa Tamotsu、Fujikawa Koshi、Takahashi Yasuo、Okuda Toshinori、Minami Shinya、Takahashi Minoru、Okamoto Tetsuro、Takada Kohichi、Miyanisi Koji、Takayama Tetsuji、Kato Junji
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 80 Issue: 4 Pages: 707-713
- DOI
  10.1007/s00280-017-3404-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K06857
[Journal Article] Hepatitis C virus reactivation due to antiemetic steroid therapy during treatment of hepatocellular carcinoma2017
- Author(s)
  Kawano Yutaka、Miyanishi Koji、Takahashi Satoshi、Kubo Tomohiro、Ishikawa Kazuma、Sugita Shintaro、Takada Kohichi、Kobune Masayoshi、Hasegawa Tadashi、Kato Junji
- Journal Title
  
  J Infect Chemother
  
  Volume: 23 Issue: 5 Pages: 323-325
- DOI
  10.1016/j.jiac.2016.12.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03599
[Journal Article] Ofatumumab combined with chlorambucil for previously untreated chronic lymphocytic leukemia: a phase I/II, open-label study in Japan2017
- Author(s)
  Hatake Kiyohiko、Ogura Michinori、Takada Kohichi、Taniwaki Masafumi、Zhang Fanghong、Fujita Taizo、Ando Kiyoshi
- Journal Title
  
  Int J Hematol
  
  Volume: 106 Issue: 2 Pages: 240-247
- DOI
  10.1007/s12185-017-2233-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma2017
- Author(s)
  Arihara Yohei、Takada Kohichi、Kamihara Yusuke、Hayasaka Naotaka、Nakamura Hajime、Murase Kazuyuki、Ikeda Hiroshi、Iyama Satoshi、Sato Tsutomu、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 39 Pages: 65889-65899
- DOI
  10.18632/oncotarget.19508
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K09482
[Journal Article] Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms.2016
- Author(s)
  Horiguchi H, Murase K, Kato J. et al
- Journal Title
  
  Haematologica
  
  Volume: 101 Issue: 4 Pages: 437-447
- DOI
  10.3324/haematol.2015.134932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26670386
[Journal Article] The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.2016
- Author(s)
  Kamihara Y, Murase K, Kato J, et al
- Journal Title
  
  Oncotarget
  
  Volume: 27 Issue: 39 Pages: 64330-64341
- DOI
  10.18632/oncotarget.11830
- NAID
  120006576953
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
[Journal Article] Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells.2016
- Author(s)
  Okagawa Y, Murase K, Kato J, et al
- Journal Title
  
  PLoS One.
  
  Volume: 15 Issue: 12 Pages: e0168355-e0168355
- DOI
  10.1371/journal.pone.0168355
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
[Journal Article] Narrow-Band Ultraviolet B Phototherapy Ameliorates Acute Graft-Versus-Host Disease of the Intestine by Expansion of Regulatory T Cells.2016
- Author(s)
  Hashimoto A, Murase K, Kato J. et al
- Journal Title
  
  PLoS One
  
  Volume: 31 Issue: 3 Pages: e0152823-e0152823
- DOI
  10.1371/journal.pone.0152823
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461429, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26670178, KAKENHI-PROJECT-26670386
[Journal Article] A phase II trial of small-dose bortezomib, lenalidomide and dexamethasone (sVRD) as consolidation/maintenance therapy in patients with multiple myeloma.2016
- Author(s)
  Ibata S, Sato T, Kuroda H, Nagamachi Y, Iyama S, Fujimi A, Kamihara Y, Konuma Y, Yoshida M, Tatekoshi A, Hashimoto A, Horiguchi H, Ono K, Murase K, Takada K, Miyanishi K, Kobune M, Hirayama Y, Kato J.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 78 Pages: 1041-1049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Journal Article] Effect of duloxetine in Japanese patients with chemotherapy-induced peripheral neuropathy: a pilot randomized trial.2015
- Author(s)
  Hirayama Y, Ishitani K, Sato Y, Iyama S, Takada K, Murase K, Kuroda H, Nagamachi Y, Konuma Y, Fujimi A, Sagawa T, Ono K, Horiguchi H, Terui T, Koike K, Kusakabe T, Sato T, Takimoto R, Kobune M, Kato J
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 20 Issue: 5 Pages: 866-871
- DOI
  10.1007/s10147-015-0810-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09482, KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430
[Journal Article] A dose-escalation study of oxaliplatin/capecitabine/irinotecan (XELOXIRI) and bevacizumab as a first-line therapy for patients with metastatic colorectal cancer.2015
- Author(s)
  Sato Y, Ohnuma H, Hirakawa M, Takahashi M, Osuga T, Okagawa Y, Murase K, Takada K, Kawano Y, Iyama S, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Okita K, Mizuguchi T, Furuhata T, Hirata K, Kato J
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 75 Issue: 3 Pages: 587-597
- DOI
  10.1007/s00280-014-2672-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09508
[Journal Article] BAK is a predictive and prognostic biomarker for the therapeutic effect of docetaxel treatment in patients with advanced gastric cancer.2015
- Author(s)
  Kubo T, Takada K, Kato J, et al
- Journal Title
  
  Gastric Cancer
  
  Volume: 0 Pages: 0-0
- NAID
  40020881713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Effect of duloxetine in Japanese patients with chemotherapy-induced peripheral neuropathy: a pilot randomized trial2015
- Author(s)
  Hirayama Y, Takada K, Kato J, et al
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Increased duodenal iron absorption through upregulation of DMT1 due to enhancement of IRP1 activity in patients with NASH.2015
- Author(s)
  Hoki T, Miyanishi K, Kato J, et al.
- Journal Title
  
  Hepatology
  
  Volume: 印刷中 Issue: 3 Pages: 751-761
- DOI
  10.1002/hep.27774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591027, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09013, KAKENHI-PROJECT-15K09482
[Journal Article] Anti-erythropoietin receptor antibody-associated pure red cell aplasia accompanied by Coombs-negative autoimmune hemolytic anemia in a patient with T cell/histiocyte-rich large B cell lymphoma2014
- Author(s)
  Fujimi A, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 100 Issue: 5 Pages: 490-3
- DOI
  10.1007/s12185-014-1652-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway2014
- Author(s)
  Zhao JJ, Takada K, Carrasco R, et al
- Journal Title
  
  Cancer Research
  
  Volume: 15 Pages: 1801-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A novel strategy inducing autophagic cell death in Burkitt's lymphoma cells with anti-CD19-targeted liposomal rapamycin2014
- Author(s)
  Ono K, Takada K, Kato J, et al
- Journal Title
  
  Blood Cancer J
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer2014
- Author(s)
  Hashimoto A, Takada K, Kato J, et al
- Journal Title
  
  Case Rep Oncol
  
  Volume: 17 Issue: 2 Pages: 316-22
- DOI
  10.1159/000363100
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Efficacy of Enteral Supplementation Enriched with Glutamine, Fiber, and Oligosaccharide on Mucosal Injury following Hematopoietic Stem Cell Transplantation2014
- Author(s)
  Iyama S, Sato T, Tatsumi H, Hashimoto A, Tatekoshi A, Kamihara Y, Horiguchi H, Ibata S, Ono K, Murase K, Takada K, Sato Y, Hayashi T, Miyanishi K, Akizuki E, Nobuoka T, Mizuguchi T, Takimoto R, Kobune M, Hirata K, Kato J.
- Journal Title
  
  Case Rep Oncol
  
  Volume: 7 Issue: 3 Pages: 692-699
- DOI
  10.1159/000368714
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591427, KAKENHI-PROJECT-25461430
[Journal Article] RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells2014
- Author(s)
  Tamura F, Takada K, Kato J, et al
- Journal Title
  
  Gastric Cancer
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] リツキシマブが奏効した難治性の混合式自己免疫性溶血性貧血2014
- Author(s)
  小野薫，高田弘一，加藤淳二，他
- Journal Title
  
  臨床血液
  
  Volume: 54 Pages: 2053-5
- NAID
  130004920528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A role for peripherally inserted central venous catheters in the prevention of catheter-related blood stream infections in patients with hematological malignancies2014
- Author(s)
  Sakai T, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 100 Issue: 6 Pages: 592-8
- DOI
  10.1007/s12185-014-1677-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Successful Treatment with Entecavir for Reactivation of Hepatitis B Virus Following Systemic Chemotherapy in a Hepatitis B Surface Antigen-negative Patient with Colorectal Cancer2014
- Author(s)
  Okagawa Y, Takada K, Kato J, et al
- Journal Title
  
  Internal Medicine
  
  Volume: 0 Pages: 0-0
- NAID
  130004678403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Narrowband ultraviolet B phototherapy ameliorates acute graft-versus-host disease by a mechanism involving in vivo expansion of CD4+CD25+Foxp3+ regulatory T cells2014
- Author(s)
  Iyama S, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 0 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Radiation-induced leiomyosarcoma of the prostate after brachytherapy for prostatic adenocarcinoma2014
- Author(s)
  Horiguchi H, Takada K, Kato J, et al
- Journal Title
  
  Case Rep Oncol
  
  Volume: 16 Issue: 2 Pages: 565-70
- DOI
  10.1159/000366294
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Pazopanibが有効であった転移性横紋筋肉腫の一例2014
- Author(s)
  橋本亜香利，高田弘一，加藤淳二，他
- Journal Title
  
  癌と化学療法
  
  Volume: 0 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] TRIM13(RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NFKappa B pathway and proteasome activity2013
- Author(s)
  Gatt ME, Takada K, Carrasco DR, et al
- Journal Title
  
  Br J Haematol
  
  Volume: 162 Pages: 21-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] A case of idiopathic encapsulating peritoneal sclerosis with intractable ileus successfully treated by surgery and steroid therapy2013
- Author(s)
  Ikeda Y, Takada K, Kato J, et al
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 6 Pages: 295-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] TRIM13(RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NFKappa B pathway and proteasome activity.2013
- Author(s)
  Gatt ME, Takada K, Mani M, Lerner M, Pick M, Hideshima T, Carrasco DE, Protopopov A, Ivanova E, Sangfelt O, Grander D, Barlogie B, Shaughessy JD Jr, Anderson KC, Carrasco DR
- Journal Title
  
  Br J Haematol
  
  Volume: 162 Issue: 2 Pages: 210-220
- DOI
  10.1111/bjh.12365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker.2013
- Author(s)
  Hirakawa M, Sato Y, Ohnuma H, Takayama T, Sagawa T, Nobuoka T, Harada K, Miyamoto H, Sato Y, Takahashi Y, Katsuki S, Hirayama M, Takahashi M, Ono M, Maeda M, Takada K, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Hirata K, Kato J
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 71 Issue: 3 Pages: 789-797
- DOI
  10.1007/s00280-013-2073-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24659372
[Journal Article] A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker2013
- Author(s)
  Hirakawa M, Takada K, Kato J, et al
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 71 Pages: 789-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Fucosylated TGF-β receptors transduces a signal for epithelial-mesenchymal transition in colorectal cancer cells2013
- Author(s)
  Hirakawa M, Takada K, Kato J, et al
- Journal Title
  
  Br J Cancer
  
  Volume: 110 Pages: 156-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461430
[Journal Article] Targeting anticancer drug delivery to pancreatic cancer cells using a fucose-bound nanoparticle approach.2012
- Author(s)
  Yoshida M, Takimoto R, Murase K, Sato Y, Hirakawa M, Tamura F, Sato T, Iyama S, Osuga T, Miyanishi K, Takada K, Hayashi T, Kobune M, Kato J.
- Journal Title
  
  PLoS One
  
  Volume: 7(7) Issue: 7 Pages: e39545-e39545
- DOI
  10.1371/journal.pone.0039545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590921, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-24659372
[Journal Article] Intermittent administration ofrecombinant human soluble thrombomodulin successfully controlled chronic disseminated intravascular coagulation in a patient with dissecting aortic aneurysm on an outpatient basis.2012
- Author(s)
  Iyama S, Sato T, et al.
- Journal Title
  
  Blood Coagul Fibrinolysis.
  
  Volume: 23 Issue: 6 Pages: 548-50
- DOI
  10.1097/mbc.0b013e32835510d6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591043, KAKENHI-PROJECT-23890169
[Journal Article] Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms.2012
- Author(s)
  Kobune M, Iyama S, Kikuchi S, Horiguchi H, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kamihara Y, Hayashi T, Miyanishi K, Sato Y, Takimoto R, Kato J.
- Journal Title
  
  Blood Cancer J
  
  Volume: 2 Issue: 9 Pages: e87-e87
- DOI
  10.1038/bcj.2012.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Improvement of iron-mediated oxidative DNA damage in patients with transfusion-dependent myelodysplastic syndrome by treatment with deferasirox.2012
- Author(s)
  Kikuchi S, Kobune M, Iyama S, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kaneko Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 23(6) Issue: 4 Pages: 548-550
- DOI
  10.1016/j.freeradbiomed.2012.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24659466
[Journal Article] Prognostic significance of serum ferritin level at diagnosis in myelodysplastic syndrome2012
- Author(s)
  Kikuchi S, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] catenin is dramatically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway.2012
- Author(s)
  Sukhdeo K, Mani M, Hideshima T, Takada K, Pena-Cruz V, Mendez G, Ito S, Anderson KC, Carrasco DR
- Journal Title
  
  Leukemia
  
  Volume: 26(5) Issue: 5 Pages: 1116-1119
- DOI
  10.1038/leu.2011.303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Targeted Disruption of the BCL9/・-catenin Complex Inhibits Oncogenic Wnt Signaling.2012
- Author(s)
  Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulcinti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR
- Journal Title
  
  Sci Transl Med
  
  Volume: 4(148) Issue: 148 Pages: 148-117
- DOI
  10.1126/scitranslmed.3003808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Diagnostic validity of CT gastrography versus gastroscopy for primary lesions in gastric cancer: evaluating the response to chemotherapy, a retrospective analysis.2012
- Author(s)
  Takahashi S, Hirayama M, Kuroiwa G, Kawano Y, Takada K, Sato T, Miyanishi K, Sato Y, Takimoto R, Kobune M, Kato J.
- Journal Title
  
  Gatric Cancer
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Prognostic significance of serum-ferritin level at diagnosis in myelodysplastic syndrome2012
- Author(s)
  Kobune M, et al. 2^<nd>
- Journal Title
  
  Int J Hematol
  
  Volume: (In press) Issue: 5 Pages: 527-534
- DOI
  10.1007/s12185-012-1048-3
- NAID
  10030633185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24659372, KAKENHI-PROJECT-24659466
[Journal Article] Successful treatment bu fibrin glue sealant for pneumothorax with chronic GVHD resistant to autologous blood patch pleurodesis.2012
- Author(s)
  Iyama S, Sato T, Murase K, Kikuchi S, Kamihara Y, Ono K, Takada K, Miyanishi K, Sato Y, Takimoto R, Kobune M, Obama T, Miyajima M, Watanabe A, Higami T, Hirayama Y, Kato J.
- Journal Title
  
  Intern Med
  
  Volume: 51(15) Pages: 2011-2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] UGT1A1*28 and *6polymorphisms and nilotinib-induced unconjugated hyperbilirubinemia in a Japanese patient with chronic myelogenous leukemia.2012
- Author(s)
  Takada K, Sato T, Iyama S, Ono K, Kamihara Y, Murase K, Kawano Y, Hayashi T, Miyanishi K, Sato Y, Kobune M, Takimoto R, Kato J
- Journal Title
  
  Int Canc Conf J201
  
  Volume: 1 Pages: 220-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] b-catenin is dramatically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway2011
- Author(s)
  Suhhdeo K, Takada K, Carrasco DR, et al
- Journal Title
  
  Leukemia
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Pages: 715-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Novel missense mutation in the TMPRSS6 gene in a Japanese female with iron-refractory deficiency anemia2011
- Author(s)
  Sato T, Takada K, Kato J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Pages: 101-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Iron chelator deferasirox rescued mice from Fas-induced fulminant hepatitis2011
- Author(s)
  Sato T, Takada K, Kato J, et al
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M, Takimoto R, Kato, J
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Issue: 6 Pages: 715-719
- DOI
  10.1007/s12185-011-0878-8
- NAID
  10029535427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231, KAKENHI-PROJECT-23890169
[Journal Article] Novel missense mutation in the TMPRSS6 gene in a Japanese female with iron-refractory iron deficiency anemia2011
- Author(s)
  Sato T, Takimoto R, Kato J
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Issue: 1 Pages: 101-103
- DOI
  10.1007/s12185-011-0881-0
- NAID
  10029536603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231, KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-22591043, KAKENHI-PROJECT-23890169
[Presentation] Extravesicular Mir-7977 Released from Leukemic Cells Inhibites the PCBP1-Mediated mRNA Stabilization and Hippo-YAP Signaling Pathway in Bone Marrow Mesenchymal Stromal Cells.2018
- Author(s)
  Masahiro Yoshida, Kohichi Takada
- Organizer
  ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Presentation] Combination of eribulin plus Akt inhibitor evokes synergistic cytotoxicity in soft tissue sarcoma cells.2018
- Author(s)
  Kohichi Takada
- Organizer
  Annual Meeting of the American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Presentation] p53-restoring small molecule CP-31398 induced apoptosis via induction of reactive oxidative species in human multiple myeloma2017
- Author(s)
  Yohei Arihara, Kohichi Takada
- Organizer
  European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178
[Presentation] Exosomal microRNAs in bone marrow cavity induce stromal dysfunction in AML/MDS2015
- Author(s)
  Hiroto Horiguchi, Masayoshi Kobune, Shohei Kikuchi, Kazuyuki Murase, Satoshi Iyama, Kohichi Takada, Tsutomu Sato, Yasushi Sato1), Koji Miyanishi1), Rishu Takimoto, Hiroyuki Kuroda, Masahiro Maeda, Junji Kato
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県金沢市ホテル日航金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K09482
[Presentation] BCL9/beta-catenin 転写複合体を標的とした新規大腸癌治療法の開発2012
- Author(s)
  高田弘一
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] BCL9/β-catenin 転写複合体を標的とした新規大腸癌治療法の開発2012
- Author(s)
  高田弘一
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] BCL9は大腸癌および多発性骨髄腫において細胞増殖,浸潤・転移能および腫瘍血管新生を亢進させる2011
- Author(s)
  高田弘一, 加藤淳二, Carrasco DR
- Organizer
  第91回北海道医学大会腫瘍系分科会
- Place of Presentation
  札幌医科大学
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23890169
[Presentation] 非アルコール性脂肪性肝炎における鉄代謝異常の分子機構解析2007
- Author(s)
  高田弘一
- Organizer
  第49回日本消化器病学会大会
- Place of Presentation
  神戸
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19590780

1. KATO JUNJI (20244345)

# of Collaborated Projects: 9 results

# of Collaborated Products: 32 results
2. TAKIMOTO Rishu (10336399)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. KOBUNE MASAYOSHI (90336389)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. Murase Kazuyuki (90444918)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. Emori Makoto (20580286)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. 高澤啓 (00593021)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. SATO Yasushi (80343383)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 在原洋平 (30749586)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. 宮西浩嗣 (60372819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
10. 中橋尚也 (90972943)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. KAMIHARA YUSUKE (10624421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 佐藤勉 (40404602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 堀口拓人 (70634674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 早坂尚貴 (00792665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大須賀崇裕 (40619714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 中村元 (10792666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. 村橋靖崇 (90855842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 村松丈児 (30933733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 清水淳也 (00826802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 房川祐頼 (30868112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 佐藤達也 (40592473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 大沼啓之 (60582997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 久保智洋 (00634669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 井山諭 (50398319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. NAGATA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. NAGAYAMA Minoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 水口徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 佐藤昇志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 平田公一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 田中信悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takada Kohichi 高田 弘一

TAKADA Koichi 高田 弘一

高田 弘一 タカダ コウイチ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development a novel immnunotherapy for hepatocellular carcinoma targeted by BRG1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development a novel therapy for hepatocellular carcinoma by targeting STEAP1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Reactive oxygen species play roles in multiple myeloma pathogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identifing novel therapeutic target molecules in multiple myeloma using BCL9-ChIPSeqPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Targeted disruption of the BCL9/beta-catenin complex in colorectal cancer using stapled peptidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Takada Kohichi 高田弘一

TAKADA Koichi 高田弘一

高田弘一タカダコウイチ

[Book] 血液症候群（第２版）　薬剤誘発性赤芽球癆2013