Kanemitsu Yoshitomi 金光祥臣

… Alternative Names

KANEMITSU Yoshitomi 金光祥臣

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Researcher Number	30752943
Other IDs
Affiliation (Current)	2023: 新潟大学, 医歯学総合病院, 特任助教
Affiliation (based on the past Project Information) *help	2019 – 2022: 新潟大学, 医歯学総合病院, 特任助教 2016 – 2017: 東北大学, 薬学研究科, 助手
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related / Medical pharmacy / Medical Physics and Radiological Technology
Keywords	Principal Investigator プロテオミクス / 放射線耐性細胞 / 放射線耐性 / メタボロミクス / 脂肪酸合成酵素 / がん細胞 / peroxiredoxin / PDI / Prx4 / オミクス解析 / TXNDC5 / トランスオミクス / iMPAQT

トランスオミクス解析によるがん細胞の放射線耐性応答ネットワーク解明Principal Investigator
- Principal Investigator
  
  金光祥臣
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Niigata University
Development of new therapeutic strategies to overcome cancer radioresistance; focusing on molecules that are increased in resistant cell linesPrincipal Investigator
- Principal Investigator
  
  KANEMITSU Yoshitomi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Niigata University
Elucidation of the mechanism of radioresistance in cancer cells using trans-omics approach and development of clinical biomarkers for radiotherapy.Principal Investigator
- Principal Investigator
  
  Kanemitsu Yoshitomi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
  Medical Physics and Radiological Technology
- Research Institution
  Tohoku University

All 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS2019
- Author(s)
  Kanemitsu Yoshitomi、Mishima Eikan、Maekawa Masamitsu、Matsumoto Yotaro、Saigusa Daisuke、Yamaguchi Hiroaki、Ogura Jiro、Tsukamoto Hiroki、Tomioka Yoshihisa、Abe Takaaki、Mano Nariyasu
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 19075-19075
- DOI
  10.1038/s41598-019-55600-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06651, KAKENHI-PROJECT-18K06742, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-19K17258
[Journal Article] The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice2018
- Author(s)
  Izumi H, Shinoda Y, Saito T, Saido TC, Sato K, Yabuki Y, Matsumoto Y, Kanemitsu Y, Tomioka Y, Abolhassani N, Nakabeppu Y, Fukunaga K.
- Journal Title
  
  Neuroscience
  
  Volume: 377 Pages: 87-97
- DOI
  10.1016/j.neuroscience.2018.02.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15456, KAKENHI-PROJECT-17H01391, KAKENHI-PROJECT-16J02855, KAKENHI-PROJECT-16K20909, KAKENHI-PROJECT-16H05219
[Journal Article] Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model.2018
- Author(s)
  Mishima Eikan、Fukuda Shinji、Kanemitsu Yoshitomi、Saigusa Daisuke、Mukawa Chikahisa、Asaji Kei、Matsumoto Yotaro、Tsukamoto Hiroki、Tachikawa Tatsuki、Tsukimi Tomoya、Fukuda Noriko N、Ito Sadayoshi、Soga Tomoyoshi、Tomioka Yoshihisa、Abe Takaaki
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 印刷中 Pages: 824-833
- DOI
  10.1152/ajprenal.00314.2017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19474, KAKENHI-PROJECT-16K20909, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-18K08199, KAKENHI-PROJECT-16H04901, KAKENHI-PROJECT-18H02822
[Journal Article] Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS?based metabolomics approach2017
- Author(s)
  †Mishima, E., †Fukuda, S. (†equally contributed), Mukawa, C., Yuri, A., Kanemitsu, Y., Matsumoto, Y., Akiyama, Y., Fukuda, NN., Tsukamoto, H., Asaji, K., Shima, H., Kikuchi, K., Suzuki, T., Tomioka, Y., Soga, T., Ito, S., Abe, T.
- Journal Title
  
  Kidney international
  
  Volume: 92 Pages: 634-645
- DOI
  10.1016/j.kint.2017.02.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04901, KAKENHI-PROJECT-16K19474, KAKENHI-PROJECT-16K20909
[Journal Article] An inhibitory epitope of human Toll-like receptor 4 resides on leucine-rich repeat 13 and is recognized by a monoclonal antibody2017
- Author(s)
  Tsukamoto Hiroki、Yamagata Yuki、Ukai Ippo、Takeuchi Shino、Okubo Misaki、Kobayashi Yohei、Kozakai Sao、Kubota Kanae、Mumasaki Muneo、Kanemitsu Yoshitomi、Matsumoto Yotaro、Tomioka Yoshihisa
- Journal Title
  
  FEBS Letters
  
  Volume: 591 Pages: 2406-2416
- DOI
  10.1002/1873-3468.12768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20909
[Journal Article] Simultaneous quantitative analysis of uremic toxins by LC-MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column2017
- Author(s)
  Kanemitsu Yoshitomi、Asaji Kei、Matsumoto Yotaro、Tsukamoto Hiroki、Saigusa Daisuke、Mukawa Chikahisa、Tachikawa Tatsuki、Abe Takaaki、Tomioka Yoshihisa
- Journal Title
  
  Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
  
  Volume: 1068-1069 Pages: 1-8
- DOI
  10.1016/j.jchromb.2017.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20909
[Presentation] 臨床的放射線耐性細胞を用いた定量プロテオミクス：ヒト口腔扁平上皮癌細胞放射線耐性細胞株 (SAS-R) において Peroxiredoxin 4 が放射線耐性能に重要な役割を担う2021
- Author(s)
  金光祥臣、桑原義和、福本学、富岡佳久、塚本宏樹
- Organizer
  日本放射線影響学会第64回大会
- Data Source
  KAKENHI-PROJECT-19K17258
[Presentation] 放射線耐性がん細胞における Peroxiredoxin 4 を介した放射線耐性の獲得2019
- Author(s)
  後藤裕徳、金光祥臣、桑原義和、福本学、塚本宏樹、富岡佳久
- Organizer
  宮城薬剤師学術フォーラム 2019
- Data Source
  KAKENHI-PROJECT-19K17258
[Presentation] Peroxiredoxin 4は臨床的放射線耐性口腔扁平上皮癌細胞の耐性能に寄与する2019
- Author(s)
  後藤裕徳、金光祥臣、桑原義和、福本学、塚本宏樹、富岡佳久
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-19K17258
[Presentation] 多層オミクス手法による放射線耐性化関連分子の探索2018
- Author(s)
  富岡佳久、金光祥臣、松本洋太郎、桑原義和、福本　学、塚本宏樹
- Organizer
  第3回治療耐性がん細胞研究協議会セミナー
- Data Source
  KAKENHI-PROJECT-16K20909
[Presentation] LC-HDMS および IMS を用いたヒト肝癌組織メタボロミクスによる新規バイオマーカーの同定2017
- Author(s)
  永井滉士、三枝大輔、山崎貴広、金光祥臣、塚本宏樹、池田均、矢冨裕、松本洋太郎、富岡佳久
- Organizer
  第56回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-16K20909
[Presentation] ミックスドモード ODS カラムを用いた LC-MS/MS による尿毒症物質一斉定量系の構築2017
- Author(s)
  金光祥臣、淺地圭、松本洋太郎、塚本宏樹、三枝大輔、阿部高明、富岡佳久
- Organizer
  第56回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-16K20909

1. TOMIOKA Yoshihisa (00282062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. MATSUMOTO Yotato (90420041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. TSUKAMOTO Hiroki (70423605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. FUKUMOTO Manabu (60156809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KUWAHARA Yoshikazu (00392225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 福田真嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 三島英換

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 矢吹悌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中別府雄作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 福永浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 鈴木健弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 阿部高明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 山口浩明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kanemitsu Yoshitomi 金光 祥臣

KANEMITSU Yoshitomi 金光 祥臣

Research Projects

Research Products

Co-Researchers

トランスオミクス解析によるがん細胞の放射線耐性応答ネットワーク解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new therapeutic strategies to overcome cancer radioresistance; focusing on molecules that are increased in resistant cell linesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of radioresistance in cancer cells using trans-omics approach and development of clinical biomarkers for radiotherapy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS?based metabolomics approach2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An inhibitory epitope of human Toll-like receptor 4 resides on leucine-rich repeat 13 and is recognized by a monoclonal antibody2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simultaneous quantitative analysis of uremic toxins by LC-MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 臨床的放射線耐性細胞を用いた定量プロテオミクス：ヒト口腔扁平上皮癌細胞放射線耐性細胞株 (SAS-R) において Peroxiredoxin 4 が放射線耐性能に重要な役割を担う2021

Author(s)

Organizer

Data Source

[Presentation] 放射線耐性がん細胞における Peroxiredoxin 4 を介した放射線耐性の獲得2019

Author(s)

Organizer

Data Source

[Presentation] Peroxiredoxin 4は臨床的放射線耐性口腔扁平上皮癌細胞の耐性能に寄与する2019

Author(s)

Organizer

Data Source

[Presentation] 多層オミクス手法による放射線耐性化関連分子の探索2018

Author(s)

Organizer

Data Source

[Presentation] LC-HDMS および IMS を用いたヒト肝癌組織メタボロミクスによる新規バイオマーカーの同定2017

Author(s)

Organizer

Data Source

[Presentation] ミックスドモード ODS カラムを用いた LC-MS/MS による尿毒症物質一斉定量系の構築2017

Author(s)

Organizer

Data Source

Kanemitsu Yoshitomi 金光祥臣

KANEMITSU Yoshitomi 金光祥臣