Hasebe shigeru 長谷部茂

… Alternative Names

長谷部茂ハセベシゲル

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Researcher Number	30754725
Other IDs
Affiliation (Current)	2025: 摂南大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2016 – 2017: 大阪大学, 歯学研究科, 助教
Review Section/Research Field	Principal Investigator Applied pharmacology Except Principal Investigator Pharmacology in pharmacy
Keywords	Principal Investigator 脳神経疾患 / 薬理学 / ドパミン神経系 / 前頭葉 / 5-HT1A受容体 / σ1受容体 Except Principal Investigator 脳神経疾患 / 薬理学 / Resident-intruder試験 / Resident-Intruder試験 … More / 覚せい剤精神病 / 難治性うつ病 / 自閉症 / 樹状突起スパイン / 豊かな環境飼育 / 社会的相互作用試験 / エンカウンター試験 / 発達障害 / 精神疾患 Less

Neurochemical study for cognitive behavioral therapy in mouse models of neuropsychiatric and neurodevelopmental disorders
- Principal Investigator
  
  Takuma Kazuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University
前頭葉ドパミン神経機能を制御するシグナル間相互作用の分子基盤解明Principal Investigator
- Principal Investigator
  
  長谷部茂
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Osaka University

All 2018 2017 2016

All Journal Article Presentation

[Journal Article] Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism2017
- Author(s)
  Hara Y, Ago Y, Higuchi M, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Hormones and Behavior
  
  Volume: 96 Pages: 130-136
- DOI
  10.1016/j.yhbeh.2017.09.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Psychopharmacology of combined activation of the serotonin1A and σ1 receptors2017
- Author(s)
  Ago Y, Hasebe S, Hiramatsu N, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 809 Pages: 172-177
- DOI
  10.1016/j.ejphar.2017.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126
[Journal Article] Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain.2017
- Author(s)
  Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K.
- Journal Title
  
  Molecular Autism
  
  Volume: 8 Issue: 1 Pages: 33-33
- DOI
  10.1186/s13229-017-0149-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Regulation of emotional behaviors by juvenile environmental factors2017
- Author(s)
  Takuma K, Ago Y, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T.
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 149 Issue: 2 Pages: 76-78
- DOI
  10.1254/fpj.149.76
- NAID
  130005306348
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19183
[Journal Article] Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice2017
- Author(s)
  Hara Y, Ago Y, Taruta A, Hasebe S, Kawase H, Tanabe W, Tsukada S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: 234(21) Issue: 21 Pages: 3217-3228
- DOI
  10.1007/s00213-017-4703-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice2017
- Author(s)
  Hasebe S, Ago Y, Watabe Y, Oka S, Hiramatsu N, Tanaka T, Umehara C, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 174 Issue: 4 Pages: 314-327
- DOI
  10.1111/bph.13692
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J06155, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183, KAKENHI-PROJECT-26293020
[Journal Article] Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice2017
- Author(s)
  Yamaguchi H, Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 333 Pages: 67-73
- DOI
  10.1016/j.bbr.2017.06.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency2016
- Author(s)
  Ago Y, Hasebe S, Hiramatsu N, Mori K, Watabe Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Psychopharmacology(Berl)
  
  Volume: 233(17) Issue: 17 Pages: 3125-3134
- DOI
  10.1007/s00213-016-4353-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K18874, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183
[Journal Article] Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice2016
- Author(s)
  Higashino K, Ago Y, Umeki T, Hasebe S, Onaka Y, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Psychopharmacology (Berl).
  
  Volume: 233(3) Issue: 3 Pages: 521-528
- DOI
  10.1007/s00213-015-4123-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670122, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-15J03564, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K19183
[Journal Article] Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation.2016
- Author(s)
  Kawanai T, Ago Y, Watanabe R, Inoue A, Taruta A, Onaka Y, Hasebe S, Hashimoto H, Matsuda T, Takuma K.
- Journal Title
  
  Neurochemical Research
  
  Volume: 41 Pages: 2574-2584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19183
[Journal Article] Role of prefrontal serotonergic and dopaminergic systems in encounter-induced hyperactivity in methamphetamine-sensitized mice2016
- Author(s)
  Tanaka T, Ago Y, Umehara C, Imoto E, Hasebe S, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Int. J. Neuropsychopharmacol.
  
  Volume: 20 Pages: 410-420
- DOI
  10.1093/ijnp/pyw115
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-14J06155, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183, KAKENHI-PROJECT-16K08268
[Journal Article] The novel method female encounter test2016
- Author(s)
  吾郷由希夫, 長谷部　茂, 橋本　均, 田熊一敞, 松田敏夫
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 147 Issue: 4 Pages: 230-234
- DOI
  10.1254/fpj.147.230
- NAID
  130005143846
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-16K19183
[Journal Article] Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism2016
- Author(s)
  Hara Y, Ago Y, Taruta A, Katashiba K, Hasebe S, Takano E, Onaka Y, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Autism Research
  
  Volume: - Issue: 9 Pages: 926-939
- DOI
  10.1002/aur.1596
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-13J05359, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K18874, KAKENHI-PROJECT-16K19183
[Presentation] Effects of intranasal oxytocin on autism-like behavioral abnormalities in valproic acid-induced mouse model of autism2018
- Author(s)
  Yuta Hara, Yukio Ago, Momoko Higuchi, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] 発育期環境要因による神経精神疾患の発症制御2016
- Author(s)
  田熊一敞、長谷部茂、原雄大、中澤敬信、橋本均、松田敏夫、吾郷由希夫
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会　合同年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K19183
[Presentation] 自閉症モデルマウスにおける前頭前皮質ドパミン神経系の異常～ADHD治療薬による行動異常の改善2016
- Author(s)
  吾郷由希夫, 原雄大, 前田優子, 長谷部茂, 橋本均, 松田敏夫, 田熊一敞
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  ソウル市, 韓国
- Year and Date
  2016-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] 雌性マウスを用いた意欲・報酬探索行動評価試験2016
- Author(s)
  川瀬啓生, 吾郷由希夫, 長谷部茂, 岡智史, 田熊一敞, 松田敏夫, 橋本均
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館 (広島県広島市)
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] Continuous activation of dopaminergic system improves autism-related behavioral abnormalities in mice prenatally exposed to valproic acid2016
- Author(s)
  Hasebe S, Hara Y, Higuchi M, Ago Y, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Organizer
  Annual Meeting of Society for Neuroscience
- Place of Presentation
  San Diego Convention Center, SanDiego, CA, USA，
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19183
[Presentation] ドパミン神経賦活薬の慢性投与は胎仔期バルプロ酸曝露マウスの自閉症様行動を改善する2016
- Author(s)
  長谷部茂, 原雄大, 樋口桃子, 吾郷由希夫, 中澤敬信, 橋本均, 松田敏夫, 田熊一敞
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡国際会議場 (福岡県福岡市)
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] Continuous activation of dopaminergic system improves autism-related behavioral abnormalities in mice prenatally exposed to valproic acid2016
- Author(s)
  Hasebe S, Hara Y, Higuchi M, Ago Y, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Organizer
  The 46th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] ドパミン神経賦活薬の慢性投与は胎仔期バルプロ酸曝露マウスの自閉症様行動を改善する2016
- Author(s)
  長谷部茂、原雄大、樋口桃子、吾郷由希夫、中澤敬信、橋本均、松田敏夫、田熊一敞
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K19183
[Presentation] ムスカリン性アセチルコリン受容体の神経精神薬理学2016
- Author(s)
  田熊一敞、長谷部茂、中澤敬信、橋本均、松田敏夫、吾郷由希夫
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K19183
[Presentation] 自閉症モデルマウスにおける前頭前皮質ドパミン神経系の異常～ADHD治療薬による行動異常の改善2016
- Author(s)
  吾郷由希夫、原雄大、前田優子、長谷部茂、橋本均、松田敏夫、田熊一敞
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  COEX（韓国ソウル市）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-16K19183

1. Takuma Kazuhiro (90289025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 吾郷由希夫 (50403027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. MATSUDA Toshio

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. HARA Yuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. MAEDA Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 田熊一浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
7. 橋本均

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
8. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 高野敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hasebe shigeru 長谷部 茂

長谷部 茂 ハセベ シゲル

Research Projects

Research Products

Co-Researchers

Neurochemical study for cognitive behavioral therapy in mouse models of neuropsychiatric and neurodevelopmental disorders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

前頭葉ドパミン神経機能を制御するシグナル間相互作用の分子基盤解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Psychopharmacology of combined activation of the serotonin1A and σ1 receptors2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of emotional behaviors by juvenile environmental factors2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation.2016

Author(s)

Journal Title

Data Source

[Journal Article] Role of prefrontal serotonergic and dopaminergic systems in encounter-induced hyperactivity in methamphetamine-sensitized mice2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The novel method female encounter test2016

Author(s)

Journal Title

DOI

NAID

ISSN

Hasebe shigeru 長谷部茂

長谷部茂ハセベシゲル