Kobayashi Isao 小林功

Researcher Number	30774757
Other IDs
External Links
Affiliation (Current)	2021: 金沢大学, 生命理工学系, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 金沢大学, 生命理工学系, 助教 2017: 金沢大学, 自然システム学系, 助教
Review Section/Research Field	Principal Investigator Integrative animal science / Basic Section 42030:Animal life science-related Except Principal Investigator Complex Systems Disease Theory / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 44040:Morphology and anatomical structure-related
Keywords	Principal Investigator 造血幹細胞 / 血管芽細胞 / インテグリン / ゼブラフィッシュ / 発生 / 細胞接着分子 / 血液 / 血管内皮細胞 / 細胞間相互作用 Except Principal Investigator 脊椎側弯症 … More

Regulatory mechanism of osteoclasts by hormones produced in osteoblasts: analysis using fish scales as a bone modelOngoing
- Principal Investigator
  
  鈴木信雄
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  Kanazawa University
Elucidation of the integrin-dependent signaling pathway in hematopoietic stem cell development.Principal InvestigatorOngoing
- Principal Investigator
  
  小林功
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Kanazawa University
Identification of novel coupling factors produced by osteoclasts and clarification of their secretory phase
- Principal Investigator
  
  北村敬一郎
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  Kanazawa University
Establishment of a research platform for developing radical treatment and early predictive diagnostics for scoliosis through nutritional environmental signals
- Principal Investigator
  
  Eiichi Hinoi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  Gifu Pharmaceutical University
  Kanazawa University
Dynamic analysis of hematopoietic stem cell development in the dorsal aortaPrincipal Investigator
- Principal Investigator
  
  Kobayashi Isao
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Integrative animal science
- Research Institution
  Kanazawa University

All 2020 2019 2018

All Journal Article Presentation

[Journal Article] Uptake of osteoblast-derived extracellular vesicles promotes the differentiation of osteoclasts in the zebrafish scale.2020
- Author(s)
  Kobayashi J, Yamamori S, Kondo M, Kuroda J, Ikegame M, Suzuki N, Kitamura K, et al.
- Journal Title
  
  Communications Biology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06331
[Journal Article] Dual role of Jam3b in early hematopoietic and vascular development2020
- Author(s)
  Kobayashi I, Kobayashi-Sun J, Hirakawa Y, Ouchi M, Yasuda K, Kamei H, Fukuhara S, Yamaguchi M.
- Journal Title
  
  Development
  
  Volume: 147 Pages: 181040-181040
- DOI
  10.1242/dev.181040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06014, KAKENHI-PROJECT-19K06438, KAKENHI-PROJECT-19K22420, KAKENHI-PROJECT-19K22517
[Journal Article] The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway.2019
- Author(s)
  Ozaki Kakeru、Yamada Takanori、Horie Tetsuhiro、Ishizaki Atsushi、Hiraiwa Manami、Iezaki Takashi、Park Gyujin、Fukasawa Kazuya、Kamada Hikari、Tokumura Kazuya、Motono Mei、Kaneda Katsuyuki、Ogawa Kazuma、Ochi Hiroki、Sato Shingo、Kobayashi Yasuhiro、Shi Yun-Bo、Taylor Peter M.、Hinoi Eiichi
- Journal Title
  
  Sci. Signal.
  
  Volume: 12 Pages: 589-589
- DOI
  10.1126/scisignal.aaw3921
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22680, KAKENHI-PUBLICLY-18H04971, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-19H03777, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-17J06262, KAKENHI-PROJECT-18J13309, KAKENHI-PROJECT-18J22107, KAKENHI-PROJECT-17KT0051
[Journal Article] Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion2019
- Author(s)
  Rho S., Kobayashi I., Oguri-Nakamura E., Ando K., Fujiwara M., Kamimura N., Hirata H., Iida A., Iwai Y., Mochizuki N., Fukuhara S.
- Journal Title
  
  Dev. Cell
  
  Volume: 印刷中 Pages: 1-16
- DOI
  10.1016/j.devcel.2019.03.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05125, KAKENHI-PROJECT-17K19689, KAKENHI-PROJECT-16K18549, KAKENHI-PROJECT-17K15393, KAKENHI-PROJECT-17K00887, KAKENHI-PROJECT-19K22517, KAKENHI-PROJECT-19K23835, KAKENHI-PROJECT-19H01022, KAKENHI-PROJECT-16H04657
[Journal Article] RANKL, Ephrin-Eph and Wnt10b are key intercellular communication molecules regulating bone remodeling in autologous transplanted goldfish scales.2018
- Author(s)
  Tazaki Yuya、Sugitani Kayo、Ogai Kazuhiro、Kobayashi Isao、Kawasaki Haruki、Aoyama Takafumi、Suzuki Nobuo、Tabuchi Yoshiaki、Hattori Atsuhiko、Kitamura Kei-ichiro
- Journal Title
  
  Comp Biochem Physiol A Mol Integr Physiol.
  
  Volume: 225 Pages: 46-58
- DOI
  10.1016/j.cbpa.2018.06.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01353, KAKENHI-PROJECT-17K01945, KAKENHI-PROJECT-18K06331, KAKENHI-PROJECT-18K11016
[Presentation] Jam3b regulates hemato-vascular development through the repression of the Erk signaling pathway2018
- Author(s)
  Isao Kobayashi, Jingjing Kobayashi
- Organizer
  ISEH
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15393

1. Eiichi Hinoi (70360865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 北村敬一郎 (80283117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 古澤之裕 (80632306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 鈴木信雄 (60242476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 関口俊男 (40378568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 服部淳彦 (70183910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 平山順 (90510363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Fukuhara Shigetomo

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. Iida Atsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. HIRATA Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. KAMEI Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. YAMAGUCHI Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 佐藤信吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 小林泰浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 越智広樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 田渕圭章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 杉谷加代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 中島尚美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 安藤康史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 望月直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Isao 小林 功

Research Projects

Research Products

Co-Researchers

Regulatory mechanism of osteoclasts by hormones produced in osteoblasts: analysis using fish scales as a bone modelOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the integrin-dependent signaling pathway in hematopoietic stem cell development.Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel coupling factors produced by osteoclasts and clarification of their secretory phase

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a research platform for developing radical treatment and early predictive diagnostics for scoliosis through nutritional environmental signals

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamic analysis of hematopoietic stem cell development in the dorsal aortaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Uptake of osteoblast-derived extracellular vesicles promotes the differentiation of osteoclasts in the zebrafish scale.2020

Author(s)

Journal Title

Data Source

[Journal Article] Dual role of Jam3b in early hematopoietic and vascular development2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RANKL, Ephrin-Eph and Wnt10b are key intercellular communication molecules regulating bone remodeling in autologous transplanted goldfish scales.2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Jam3b regulates hemato-vascular development through the repression of the Erk signaling pathway2018

Author(s)

Organizer

Data Source

Kobayashi Isao 小林功