Kashima Makoto 鹿島誠

Researcher Number	10780562
Other IDs	https://orcid.org/0000-0002-3953-9033
Affiliation (Current)	2026: 東邦大学, 理学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 東邦大学, 理学部, 講師 2019 – 2022: 青山学院大学, 理工学部, 助教 2017: 龍谷大学, 龍谷大学食と農の総合研究所, 博士研究員 2016 – 2017: 龍谷大学, 食と農の総合研究所, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 44020:Developmental biology-related / Developmental biology Except Principal Investigator Basic Section 48040:Medical biochemistry-related / Basic Section 39020:Crop production science-related / Basic Section 57070:Developmental dentistry-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Basic Section 48010:Anatomy-related / Basic Section 45020:Evolutionary biology-related / Basic Section 38060:Applied molecular and cellular biology-related / Basic Section 42030:Animal life science-related / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 40040:Aquatic life science-related
Keywords	Principal Investigator 幹細胞 / プラナリア / RNA-Seq / piRNA / PIWI / ケミカルスクリーニング / スクリーニング / 化合物 / 全能性 / piwi … More / 再生 / RNA-seq / 免疫沈降 / 全能性幹細胞 … More Except Principal Investigator ゼブラフィッシュ / 形態形成 / 老化細胞 / V型ATPase / Nrf2経路 / 遺伝子破壊 / リソソーム / 光合成 / トランスクリプトーム / モデリング / イネ / LASSO回帰 / DeLTa-Seq / 予測モデル / MIC-100 / 光合成速度 / 野外トランスクリプトーム / 力 / 透明化 / イメージング / 細胞排除 / 細胞間コミュニケーション / 老化 / 矯正治療 / PTHシグナル / ホルモン補充療法 / 歯牙萌出不全 / 顎顔面形成不全 / 副甲状腺ホルモンシグナル / 分子遺伝学 / 社会脳 / 配偶者戦略 / バイバリーシステム / 最初期遺伝子 / 社会シグナル / 体色変化 / セレベスメダカ / シングルセルRNAseqアトラス / 視覚 / ソーシャルビジョン / 視覚フィルタリング / 自閉症 / カテゴリー学習 / scRNS-seq / 同種認知 / 異性認知 / Familiarity recognition / 社会認知 / 上丘 / 視蓋 / カテゴリ学習 / シングルセルトランスクリプトーム / カルシウムイメージング / 光遺伝学 / 他人種効果 / 顔認知 / オキシトシン / 鼓膜 / 下顎 / 舌 / 頭蓋顎顔面 / 発生進化 / 進化生物学 / 幹細胞 / 神経堤細胞 / 体成長 / 追いつき成長 / 微量金属 / OGR1 / CaMKII / Ca2+シグナリング / 進化的保存性 / 温度補償性 / 概日時計 / in vivoイメージング / 胚発生 / ゲノム毒性 / 精子 / 小児がんサバイバー / 分化 / 生活環 / 性決定 / 分子系統解析 / 系統解析 / 配偶子 / 生物伝播 / マミズクラゲ Less

The elucidation of morphological evolution in the cranio-maxillofacial region of snakes by molecular developmental analysis .
- Principal Investigator
  
  古寺敏子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45020:Evolutionary biology-related
- Research Institution
  Institute of Science Tokyo
骨と軟組織が正しい位置で連結するための分子発生メカニズムの解明
- Principal Investigator
  
  武智正樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Institute of Science Tokyo
Studying on contributing to ensuring fertility and avoiding developmental toxicity risks in paediatric cancer patients
- Principal Investigator
  
  横田理
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Institute of Health Sciences
Role of transcription factor Tfcp2l1 in growth spurt phenomena in zebrafish
- Principal Investigator
  
  亀井宏泰
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Kanazawa University
Development of a treatment method for maxillofacial dysplasia caused by parathyroid hormone (PTH) signaling disorder
- Principal Investigator
  
  黒坂寛
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Osaka University
Accumulation mechanism of senescence cells in aging and the challenge for anti-aging
- Principal Investigator
  
  松井貴輝
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Nara Institute of Science and Technology
Prediction modeling for photosynthetic dynamics of multiple rice cultivars by field transcriptome
- Principal Investigator
  
  安達俊輔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 39020:Crop production science-related
- Research Institution
  Tokyo University of Agriculture and Technology
リソソームストレスに対するNrf2活性化のメカニズムと意義
- Principal Investigator
  
  小林麻己人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  University of Tsukuba
低温適応を担うCa2+-CaMKIIシグナリング
- Principal Investigator
  
  金尚宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  Nagoya University
淡水棲マミズクラゲがもつ３つの謎（性決定、芽体形成、生物伝播）の解明に迫る
- Principal Investigator
  
  小林千余子
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Nara Medical University
プラナリア成体多能性幹細胞の維持を可能とする分子の探索Principal Investigator
- Principal Investigator
  
  鹿島誠
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Toho University
  Aoyama Gakuin University
Identification of the amino acid sequence of OGR1 to sense trace metal specificity using OGR1 orthologs.
- Principal Investigator
  
  Tomura Hideaki
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Meiji University
Molecular/genetic basis underlying the fish social vision
- Principal Investigator
  
  Takeuchi Hideaki
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Tohoku University
Identification of the targets of nuclear PIWI-piRNA complexes important for the planarian adult pluripotent stem cell systemPrincipal Investigator
- Principal Investigator
  
  Kashima Makoto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Aoyama Gakuin University
Analysis of cooperative function of PIWI proteins in gene regulation during self-renewal and differentiation of planarian pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  Kashima Makoto
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Developmental biology
- Research Institution
  Ryukoku University

All 2025 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] 誰でも再現できるNGS「前」サンプル調製プロトコール、プラナリア、長鎖ゲノム抽出法2024
- Author(s)
  熊谷信是，鹿島　誠
- Total Pages
  6
- Publisher
  羊土社
- ISBN
  9784758122726
- Data Source
  KAKENHI-PROJECT-22K15127
[Book] 誰でも再現できるNGS「前」サンプル調製プロトコール2024
- Author(s)
  鹿島誠伊藤佑尾崎遼
- Total Pages
  439
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22K05821
[Book] Direct-TRI とLasy-Seq を用いた低コスト・ハイスループットなbulk RNA-seq2023
- Author(s)
  鹿島　誠
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22K15127
[Journal Article] Expression analysis of genes including Zfhx4 in mice and zebrafish reveals a temporospatial conserved molecular basis underlying craniofacial development2024
- Author(s)
  Liu Shujie、Xu Lin、Kashima Makoto、Narumi Rika、Takahata Yoshifumi、Nakamura Eriko、Shibuya Hirotoshi、Tamura Masaru、Shida Yuki、Inubushi Toshihiro、Nukada Yuko、Miyazawa Masaaki、Hata Kenji、Nishimura Riko、Yamashiro Takashi、Tasaki Junichi、Kurosaka Hiroshi
- Journal Title
  
  Developmental Dynamics
  
  Volume: 254 Issue: 3 Pages: 257-271
- DOI
  10.1002/dvdy.740
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24H00651, KAKENHI-PROJECT-23K27803, KAKENHI-PROJECT-23K17438
[Journal Article] A resource of single‐cell gene expression profiles in a planarian <scp><i>Dugesia japonica</i></scp>2023
- Author(s)
  Kashima Makoto、Komura Rei、Sato Yuki、Hashimoto Chikara、Hirata Hiromi
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 66 Issue: 1 Pages: 43-55
- DOI
  10.1111/dgd.12893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15127, KAKENHI-PROJECT-19H03329
[Journal Article] Planarian Piwi-piRNA interaction analysis using immunoprecipitation and piRNA-Sequencing2022
- Author(s)
  Makoto Kashima, Atsumi Miyata, Norito Shibata
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: NA
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16149
[Journal Article] Searching for non-transposable targets of planarian nuclear PIWI in pluripotent stem cells and differentiated cells2018
- Author(s)
  Makoto Kashima, Kiyokazu Agata, Norito Shibata
- Journal Title
  
  Develop. Growth Differ.
  
  Volume: 4 Issue: 5 Pages: 1-18
- DOI
  10.1111/dgd.12536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07421, KAKENHI-PROJECT-16H07342
[Presentation] 野外トランスクリプトーム推定を利用したイネ個葉光合成速度およびバイオマス生産の予測2025
- Author(s)
  本田爽太郎・宮下大輝・大久保智司・鹿島誠・大川泰一郎・永野惇・安達俊輔
- Organizer
  日本作物学会第259回講演会
- Data Source
  KAKENHI-PROJECT-24K01740
[Presentation] bulk RNA-Seqでの疑似時間解析を容易にする「Rallyist」の開発2024
- Author(s)
  鈴木悠太, 保坂美朋, 鹿島誠
- Organizer
  47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] Elucidating the Dynamics of Leaf Photosynthesis in Field-Grown Rice Using Transcriptome-Based Predictive Modeling2024
- Author(s)
  Sotaro Honda, Satoshi Ohkubo, Daiki Miyashita, Makoto Kashima, Taiichiro Ookawa, Atsushi J. Nagano, Shunsuke Adachi
- Organizer
  2nd Asia-Oceania International Congress on Photosynthesis (AOICP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K01740
[Presentation] bulk RNA-Seqでの疑似時間解析を容易にする「Rallyist」の開発2024
- Author(s)
  鈴木悠太,鹿島誠
- Organizer
  第21回　東邦大学5学部合同学術集会
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] bulk RNA-Seqを用いた疑似時間解析のすゝめ2023
- Author(s)
  鹿島　誠
- Organizer
  NGS EXPO2023
- Invited
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] 淡水生プラナリアで維持・活用される成体全能性幹細胞研究の今後とこれから2023
- Author(s)
  鹿島　誠
- Organizer
  第56回日本発生生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] Intercellular and intracellular gene regulatory networks inference with individual-difference correction from time-course bulk RNA-Seq of whole embryo2022
- Author(s)
  Makoto Kashima, Yuki Shida, Takashi Yamashiro, Hiromi Hirata, Hiroshi Kurosaka
- Organizer
  第55回日本発生生物学会年会
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] WET と DRYハイブリッド研究者になるまで2022
- Author(s)
  鹿島　誠
- Organizer
  NGS発生生物学現場の会2022
- Invited
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] 時系列一個体RNA-Seqによるプラナリアの再生プロセスの観察2022
- Author(s)
  保坂美朋, 鹿島誠, 平田普三
- Organizer
  日本動物学会第93回早稲田大会
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] Transcriptomic landscape during regeneration revealed turning point of anterior-posterior information in a planarian, Dugesia japonica.2022
- Author(s)
  Miho Hosaka, Makoto Kashima, Hiromi Hirata
- Organizer
  第55回日本発生生物学会年会
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] 成体多能性幹細胞の制御メカニズム解明に向けたケミカルスクリーニング2022
- Author(s)
  河村嶺, 鹿島誠, 平田普三
- Organizer
  日本動物学会第93回早稲田大会
- Data Source
  KAKENHI-PROJECT-22K15127
[Presentation] シングルセルRNA-SeqによるプラナリアDugesia japonicaの主要細胞種遺伝子発現カタログ作成とその利用例2021
- Author(s)
  鹿島誠, 河村嶺, 保坂美朋, 平田普三
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16149
[Presentation] Single cell RNA-Seq to identify all cell types in the planarian Dugesia japonica.2021
- Author(s)
  Rei Komura, Makoto Kashima, Hiromi Hirata
- Organizer
  発生生物学年会2021
- Data Source
  KAKENHI-PROJECT-19K16149
[Presentation] 経時一個体RNA-Seqに基づくプラナリアの再生過程における網羅的ステージング2021
- Author(s)
  保坂美朋, 鹿島誠, 平田普三
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16149
[Presentation] テンソル分解に基づく教師なし学習による変数選択のRNAiを適用したプラナリアのRNA-seq解析への応用2020
- Author(s)
  田口善弘, 鹿島　誠
- Organizer
  情報処理学会バイオ情報学研究会, 2020
- Data Source
  KAKENHI-PROJECT-19K16149
[Presentation] Cooperation of nuclear and cytoplasmic PIWIs is indispensable for transposon silencing in planarian pluripotent stem cell system2019
- Author(s)
  鹿島　誠
- Organizer
  ＲＮＡフロンティアミーティング２０１９
- Data Source
  KAKENHI-PROJECT-19K16149
[Presentation] Cytoplasmic PIWI is indispensable for transposon silencing conducted by nuclear PIWI in planarian pluripotent stem cell system2017
- Author(s)
  Makoto Kashima, Kiyokazu Agata, Norito Shibata
- Organizer
  第50回日本発生生物学会年会
- Data Source
  KAKENHI-PROJECT-16H07342
[Presentation] Inheritance of nuclear PIWI coordinates stepwise gene expression in the planarian pluripotent stem cell system.2017
- Author(s)
  Makoto Kashima, Taisuke Ishiko, Osamu Nishimura, Labib Rouhana, Kazuyo Misaki, Shigenobu Yonemura, Kuniaki Saito, Haruhiko Siomi, Mikiko C. Siomi, Kiyokazu Agata and Norito Shibata
- Organizer
  RNAフロンティアミーティング2017
- Data Source
  KAKENHI-PROJECT-16H07342

1. 武智正樹 (10455355)

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2. Tomura Hideaki (70217553)

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3. Takeuchi Hideaki (00376534)

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4. 小林千余子 (20342785)

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5. 鈴木隆仁 (60771285)

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6. 横田理 (70706605)

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7. 佐藤卓也 (70599505)

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8. 吉岡弘毅 (30756606)

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9. 宮宗秀伸 (80422252)

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10. 金尚宏 (80822931)

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11. 亀井宏泰 (00610362)

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12. 小林功 (30774757)

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13. 伊藤昭博 (40391859)

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14. 古寺敏子 (90822809)

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15. 安齋賢 (20779467)

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16. 黒坂寛 (20509369)

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17. 廣瀬勝俊 (00824898)

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18. 鈴木誠 (10533193)

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19. 豊澤悟 (30243249)

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22. 松井貴輝 (60403333)

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23. 安達俊輔 (30717103)

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24. 小林麻己人 (50254941)

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25. MIYATA Atsumi

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26. HATA Kenji

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27. TAKAHATA Yoshifumi

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28. SHIBATA Norito

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29. 西村理行

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Kashima Makoto 鹿島 誠

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プラナリア成体多能性幹細胞の維持を可能とする分子の探索Principal Investigator

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Identification of the targets of nuclear PIWI-piRNA complexes important for the planarian adult pluripotent stem cell systemPrincipal Investigator

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Analysis of cooperative function of PIWI proteins in gene regulation during self-renewal and differentiation of planarian pluripotent stem cellsPrincipal Investigator

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Kashima Makoto 鹿島誠

[Presentation] 淡水生プラナリアで維持・活用される成体全能性幹細胞研究の今後とこれから2023