Tagai Kenji 互健二

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互健二タガイケンジ

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Researcher Number	30873020
Other IDs
Affiliation (Current)	2026: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所脳機能イメージング研究センター, 主任研究員 2026: 東京慈恵会医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2026: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所脳機能イメージング研究センター, 主任研究員 2022 – 2024: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所脳機能イメージング研究部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator 認知症 / 口腔内環境 / 縦断的検証 / 早期診断 / タウPET / 血液バイオマーカー / 軽度認知障害

タウPETを用いた前頭葉症候群の疾患横断的神経基盤の解明Principal Investigator
- Principal Investigator
  
  互健二
- Project Period (FY)
  2026 – 2029
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Institutes for Quantum Science and Technology
Longitudinal evaluation using tau PET for diverse tau lesions associated with mild cognitive impairment.Principal Investigator
- Principal Investigator
  
  互健二
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Institutes for Quantum Science and Technology

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Distinct tau pathologies in the nucleus basalis of Meynert between early-onset and late-onset Alzheimer's disease patients revealed by positron emission tomography2024
- Author(s)
  Suzuki Hisaomi、Tagai Kenji、Ono Maiko、Shimizu Hiroshi、Endo Hironobu、Matsumoto Hideki、Kubota Manabu、Kataoka Yuko、Moriguchi Sho、et al.
- Journal Title
  
  Journal of Alzheimer’s Disease
  
  Volume: 102 Issue: 4 Pages: 1271-1285
- DOI
  10.1177/13872877241297382
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03606, KAKENHI-PROJECT-23K24259, KAKENHI-PROJECT-24K02268, KAKENHI-PROJECT-24K02374, KAKENHI-PROJECT-24K02387, KAKENHI-PROJECT-23K06961, KAKENHI-PROJECT-22K15776, KAKENHI-PROJECT-24K19956
[Journal Article] A novel plasma p-tau181 assay as a specific biomarker of tau pathology in Alzheimer's disease2024
- Author(s)
  Kenji Tagai, Harutsugu Tatebe, Sayo Matsuura, Zhang Hong, Naomi Kokubo, Kiwamu Matsuoka, et al.
- Journal Title
  
  Translational Neurodegeneration
  
  Volume: 13 Issue: 1 Pages: 44-44
- DOI
  10.1186/s40035-024-00439-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K03164, KAKENHI-PROJECT-23K05993, KAKENHI-PROJECT-22K15776, KAKENHI-PROJECT-24K19956
[Journal Article] Association of Tooth Loss with Alzheimer’s Disease Tau Pathologies Assessed by Positron Emission Tomography2023
- Author(s)
  Matsumoto Hideki、Tagai Kenji、Endo Hironobu、Matsuoka Kiwamu、Takado Yuhei、Kokubo Naomi、Shimada Hitoshi、Goto Tetsuya、Goto Tazuko K.、Higuchi Makoto
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 96 Issue: 3 Pages: 1253-1265
- DOI
  10.3233/jad-230581
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19636, KAKENHI-PROJECT-22K15776
[Journal Article] An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607)2022
- Author(s)
  Tagai Kenji、Ikoma Yoko、Endo Hironobu、Debnath Oiendrila Bhowmik、Seki Chie、Matsuoka Kiwamu、Matsumoto Hideki、Oya Masaki、Hirata Kosei、Shinotoh Hitoshi、Takahata Keisuke、Kurose Shin、Sano Yasunori、Ono Maiko、Shimada Hitoshi、Kawamura Kazunori、Zhang Ming-Rong、Takado Yuhei、Higuchi Makoto
- Journal Title
  
  NeuroImage
  
  Volume: 264 Pages: 119763-119763
- DOI
  10.1016/j.neuroimage.2022.119763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07529, KAKENHI-PROJECT-22K19636, KAKENHI-PROJECT-22K15776, KAKENHI-PROJECT-18K07543, KAKENHI-PROJECT-20K07935
[Presentation] Development of a Novel Plasma p-Tau181 Assay Reflecting Tau Tangle Pathology in Alzheimer's Disease2024
- Author(s)
  Tagai Kenji, Tatebe Harutsugu, Higuchi Makoto, Tokuda Takahiko
- Organizer
  第65回日本神経学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15776
[Presentation] タウ・シヌクレインPETの開発とその現況2024
- Author(s)
  互　健二
- Organizer
  第43回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15776
[Presentation] Development and Comparison of a Novel Mid-Region Directed p-Tau 181 Assay with Tau Positron Emission Tomography in Alzheimer's Disease2023
- Author(s)
  Kenji Tagai, Harutsugu Tatebe, Sayo Matsuura, et al.
- Organizer
  The Alzheimer's Association International Conference 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15776
[Presentation] アルツハイマー病診断における神経病理イメージングの活用2023
- Author(s)
  互健二
- Organizer
  第42回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15776

1. 小野麻衣子

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# of Collaborated Products: 1 results
2. 後藤哲哉

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# of Collaborated Products: 1 results
3. 後藤多津子

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# of Collaborated Products: 1 results
4. 樋口真人

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5. 森口翔

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6. 小久保奈緒美

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# of Collaborated Products: 1 results

Tagai Kenji 互 健二

互 健二 タガイ ケンジ

Research Projects

Research Products

Co-Researchers

タウPETを用いた前頭葉症候群の疾患横断的神経基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Longitudinal evaluation using tau PET for diverse tau lesions associated with mild cognitive impairment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Distinct tau pathologies in the nucleus basalis of Meynert between early-onset and late-onset Alzheimer's disease patients revealed by positron emission tomography2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel plasma p-tau181 assay as a specific biomarker of tau pathology in Alzheimer's disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of Tooth Loss with Alzheimer’s Disease Tau Pathologies Assessed by Positron Emission Tomography2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607)2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Development of a Novel Plasma p-Tau181 Assay Reflecting Tau Tangle Pathology in Alzheimer's Disease2024

Author(s)

Organizer

Data Source

[Presentation] タウ・シヌクレインPETの開発とその現況2024

Author(s)

Organizer

Data Source

[Presentation] Development and Comparison of a Novel Mid-Region Directed p-Tau 181 Assay with Tau Positron Emission Tomography in Alzheimer's Disease2023

Author(s)

Organizer

Data Source

[Presentation] アルツハイマー病診断における神経病理イメージングの活用2023

Author(s)

Organizer

Data Source

Tagai Kenji 互健二

互健二タガイケンジ