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FUJIMURA Sigefumi
藤村 重又
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Alternative Names
FUJIMURA S 藤村 重文
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Researcher Number
40006078
External Links
Affiliation (based on the past Project Information)
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1999 : 東北大学, 加齢医学研究所, 所長
1993 – 1999 : Institute of Development, Aging and Cncer, Tohoku University. Professor, 加齢医学研究所, 教授
1997 : Tohoku University, Institute Development, Aging and cancer Professor, 加齢医学研究所・呼吸器研究分野, 教授
1996 : Insitute of Development, Aging and Cancer, Tohoku University Department of Thora, 加齡医学研究所, 教授
1996 : 東北大学, 加齢医学研究所呼吸器再建研究分野, 教授
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1995 : 東北大学, 加齢医学研所・呼吸器再建研究分野, 教授
1992 : RESEARCH INSTITUTION FOR CHEST DISEASE AND CANCER:DEPARTMENT OF SURGERY:PROFESSOR, 抗酸菌病研究所外科部門, 教授
1989 – 1992 : Res. Ins. for Chest Dis. and Cancer Dep. of Surgery, Professor, 抗酸菌病研究所, 教授
1987 – 1988 : 東北大学, 抗酸菌病研究所, 助教授
Less
Review Section/Research Field
Principal Investigator
Thoracic surgery
Except Principal Investigator
Thoracic surgery
Keywords
Principal Investigator
肺移植 / 拒絶反応 / Lung transplantation / 拒絶反応監視 / Heart-Lung Transplantation / 心肺移植 / Immunosuppression / 肺保存 / Pulmonary Preservation / Lung Transplantation
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More
/ 肺水腫 / 気管支鏡 / 免疫抑制 / 心停止ドナー / Rejection Monitoring / Non-Heart-Beating Donor / 徐神経 / DENERVATION / サルモデル / 気管支肺胞洗浄 / リンパ球自然芽球化反応 / ラットモデル / 移植後病態生理 / 保存臓器の評価 / Immunological monitoring / Clinical application / allograft rejection / IMMUNOSUPPRESSION / REJECTION / 気管支擦過 / Primate / Primate lung transplantation / サル肺移植 / CARDIO-PULMONARY TRANSPLANTATION / 適応拡大 / Lung preservation / Bronchofiberscope / 腫瘍マーカー / トレランス / 脾細胞移植 / bronchofiberscope / PCR / 免疫組織染色 / Th2サイトカイン / Ep4液 / 肺および心肺保存 / 免疫阻害 / 拒絶反応診断法 / 肺・心肺保存 / 家系内発生疾患 / Function of preserved lung / Bronchoalveolar lavage fluid / 日本猿肺移植 / 副腎皮質ホルモン / 気管支粘膜血流 / ラット / 臨床応用 / 肺胞上皮機能 / in situ hybridization / 保存 / PRESERVATION / in situ PCR / 免疫抑制剤 / K-ras / 肺五検 / 肺胞水分クリアランス / Th1サイトカイン / Ep4 solution / リンゲージ解析 / 肺生検 / Lymphocyte subset / rejection / 気管支肺胞洗浄液 / 移植後肺水腫 / リンケージ解析 / 気胸 / 移植適応基準 / 点突然変異 / Thoracoscopic procedure / PULMONARY EDEMA / Lung biopsy / 嚢胞性肺疾患 / LUNG TRANSPLANTATION / Bronchial mucosal blood flow / Reection Monitoring / 霊長類 / レーザー組織血流計 / Monitoring of rejection / 遺伝子異常 / Non-Heart-Beatig Donor / soluble form CD44 / 拒絶反応診断 / 心肺保存 / リンパ球分画 / 接着因子 / 胸腔鏡 / 転移 / 肺癌 / 保存移植肺機能 / 気管支粘膜血流量 / lung transplantation
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More
Except Principal Investigator
PCR / 肺移植 / 心臓移植 / in situ hybridization / 肺傷害 / 心筋症 / 免疫抑制療法 / Immunosuppression / PCR-SSCP / 発癌 / donation / 胸部X線無所見肺癌 / 肺胞上皮細胞 / 抗接着抗体 / 補助人工心臓 / immunohistostain / 好中球 / 免疫染色 / point mutation / 慢性拒絶反応 / 遺伝子導入 / 臓器移植ネットワーク / enriched PCR / protein kinase C / in situ PCR / K-ras / Cardiac xenotransplantation / 癌抑制遺伝子p53 / 肺胞水分クリアランス / tumor supperssor gene p53 / roentgenographically occult lung cancer / 異種心移植 / 慢性肺気腫 / 心肺移植 / 血管内皮細胞 / 点突然変異 / 細胞培養 / Non-Heart-Beating Donor / イオントランスポート / 肺保存 / LUNG TRANSPLANTATION / 異種心臓移植 / Lung Transplantation / transendothelial electrical resistance / direct in situ PCR / Na+-K+-ATPase / ヒトパピローマウイルス(HPV) / gene transfer / 肺血管透過性 / 無機リン / 早期拒絶反応モニタリング / ドナー心機能 / アポトーシス関連遺伝子bc1-2 / 急性拒絶反応 / 小児肺-心臓移植 / Reperfusion injury / 肺水腫 / early detection of rejection / 肺細胞移植 / 肺扁平上皮癌 / Donation / 好中球遊走化因子 / actin / 移植臓器機能保存 / alveolar epithelial cells / reimplantation response / シグナル伝達経路 / 移植 / 肺保存液 / 抗酸化剤 / 肺高血圧 / 肺上皮・血管内皮細胞移植 / apoptosis / 異種移植 / 内皮細胞 / Cell culture / cdk inhibitor p21 / 渡航心移植 / Graft atherosclerosis / Lung transplantation in rats, dogs and monkey / non-cytotoxic agent / 抗ICAM-1抗体 / rejection / CHILDREN / Bilateral Lung Transplantation / 細胞内信号伝達系 / HEART TRANSPLANTATION / in situ bridization / 早期診断 / 阻血再潅流障害 / 虚血再灌流障害 / Isolated lung / 肺胞上皮機能 / 患者管理 / プロテインキナーゼC / enzymatic tissue digestion法 / Monitoring of early rejection / Eisenmenger症候群 / Ischemia-reperfusion injury / 術後胸水 / Polymorphonuclear leukocytes / 小児心臓移植 / Organ transp lantation network / Adgesion molecule / 転写因子 / Lung preservation after cardiac arrest / 低酸素 / PCP-SSCP法 / Organ transplantation network / donor臓器 / Ca拮抗剤 / グラフト動脈硬化症 / ラット,犬,ニホンザル肺移植 / Heart Transplantation / Enriched PCR / 原発性肺癌 / 小児脳死判定基準 / Steroid / 移植術後管理 / adjuvant therapy / Cytomegalo virus / 肺・心肺保存 / 抗CD2抗体 / 開胸術後肺傷害 / 肺胞II型上皮細胞 / HPV感染 / 心停止ドナー / 心停止後肺保存 / 肺胞洗浄液(BALF) / Heart Transp lantation / Chronic pulmonary emphysema / dination / 血管新生抑制治療 / アクチン / 脳死判定 / 胸水 / 副腎皮質ホルモン / 遺伝子治療 / 摘出灌流肺 / 臨床応用 / Lung preservation medium / indirect in situ PCR / アポトーシス関連遺伝子bcl-2 / K-RAS / Anti-adhesion molecule-antibody / 肺胞洗浄液 / PCR-SSCP法 / dormancy therapy / Myeloperoxidase / 早期肺癌 / 活性化好中球 / Lung transplantation / p21蛋白 / Intracellul signal transduction / Rejection Monitoring / 免疫抑制剤 / XENOTRANSPLANTATION / 血管新生 / 冠動脈硬化症 / 移植心冠状動脈硬化 / アポトーシス / HEART-LUNG TRANSPLANTATION / difference adherence法 / Hypoxia / 適応基準 / PECAM / Cardiomyopathy / 血管新生抑制剤 / 接着分子 / 肺癌 / p53 / Pulmonary cell preservation / BALF / 気管支吻合部血流 / Immunosuppressive agents / 肺門部早期肺癌 / gene transfer therapy / 多発癌 / 臓器機能維持 / 腫瘍血管新生 / 拒絶反応の診断 / Ion transport / 癌関連遺伝子 / left ventriular assist device / doration / DNA ポリメラーゼ / clinical study / Heart transplantation / ACTIVATED NEUTROPHILS / サイトメガロウィルス / ICAM-1 / 小児 / ras / Pulmonary vascular permeability / Dormant therapy / 癌抑制遺伝子 / Lung and heart-lung transplantation / TUNEL法 / 摘出潅流肺 / Pulmonary Preservation / vascular endothelial cells. / 肺障害 / Cardiomyoathy / 気管支吻合部創治癒 / Acute lung injury / G-CSF / donor / 遺伝子異常 / K-ras 遺伝子 / P53 / 増殖動態 / シグナル伝達回路 / mutation enrichment / 先天性心疾患 / Heart-Lung Transplantation / HPV infection / Lung injury / 接着因子 / 心移植 / 両側肺移植 / 開胸術 / bcl-2 / LUNG INJURY / 細胞内信号伝達経路 / DETERMINATION OF BRAIN DEATH / 細胞骨格 / PCR‐SSCP / TUNEL method / lung cancer / ステロイド / Wound healing of bronchial anastomotic site / 拒絶反応
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Research Projects
(
28
results)
Co-Researchers
(
38
People)
Project Start Year(Newest)
Project Start Year(Oldest)
低毒性の血管新生抑制剤の再発見-新しい戦略での肺癌術後治療臨床試験を目指して-
Principal Investigator
佐川 元保
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
嚢胞性肺疾患家系のリンケージ解析
Principal Investigator
Principal Investigator
藤村 重文
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
Studies on management of heart transplant recipients and maintenance of donor organs
Principal Investigator
TAKAMOTO Shinichi
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (A).
Research Field
Thoracic surgery
Research Institution
University of Tokyo
Detection of 1 mutant cell in normal 10^5〜10^6 cells : Genetic diagnosis using enriched PCR
Principal Investigator
SAGAWA Motoyasu
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Thoracic surgery
Research Institution
Tohoku University
STUDY OF ADHESION MOLECULES, CYTOSKELETON AND SIGNAL TRANSDUCTION PATHWAY ON INJURY OF ENDOTHELIAL CELLS FOR ISOLATED PRESERVED LUNGS
Principal Investigator
TANITA Tatsuo
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
Bronchial brushing as an early diagnostic method for lung allograft rejection in primate lung transplant mo
Principal Investigator
Principal Investigator
MATSUMURA Yuji
, 藤村 重文
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Thoracic surgery
Research Institution
Tohoku University
in situ PCR法による肺癌発癌過程における遺伝子異常局在の病理学的な解明
Principal Investigator
Principal Investigator
藤村 重文
Project Period (FY)
1997
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
開胸術後に肺傷害をもたらす胸腔内炎症の発生機序の解析と制御に関する研究
Principal Investigator
ONO Sadafumi
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
肺血管内皮細胞及び肺胞上皮細胞の移植による慢性肺気腫の治療法に関する基礎研
Principal Investigator
谷田 達男
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
MULTI-CENTER STUDIES FOR CLINICAL APPLICATION OF PEDIATRIC HEART AND LUNG TRANSPLANTATION IN JAPAN
Principal Investigator
MATSUDA Hikaru
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
OSAKA UNIVERSITY
Research Project on the Clinical Indication in Japan and the Posttransplant Patient Management in Lung and Heart-Lung Transplantation.
Principal Investigator
Principal Investigator
FUJIMURA Shigefumi
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
Experimental study on the assessment of lung preservation from the stand point of the alveolar type II epithelial cell function
Principal Investigator
KONDO Takashi
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
血中可溶性接着因子の肺癌血行性転移における意義
Principal Investigator
Principal Investigator
藤村 重文
Project Period (FY)
1996
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
Study of tolerance mechanism in a functional tolreance modrl of rat lung transplant
Principal Investigator
Principal Investigator
FUJIMURA Shigefumi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Tohoku University
A study for pulmonary cell preservation and lung transplantation on functions of alveolar epithelial ion transport
Principal Investigator
TANITA Tatsuo
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Tohoku University
Co-operative Research on Clinical Application and Functional Preservation of Heart and Heart-lung Transplantation
Principal Investigator
NAKAJIMA Jun
,
古瀬 彰
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
University of Tokyo
Assessment of genetic changes in the carcinogenesis of squamous cell lung cancer using in situ PCR.
Principal Investigator
SATO Masami
,
斎藤 泰紀
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Tohoku University
ACUTELUNG INJURY INDUCED BY HYPOXA IN RATS
Principal Investigator
ONO Sadafumi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Thoracic surgery
Research Institution
Tohoku University
Research Project to Establish the Clinical Indication and the Way for Safe Management of the Graft in Lung and Heart-Lung Transplantation.
Principal Investigator
Principal Investigator
FUJIMURA Shigefumi
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
Tohoku University
Genetical analasys of genesis of multiple primary squamous cell carcinoma of lung
Principal Investigator
SATO Masami
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Tohoku University
Study in possibility of lung transplantation from non-heart beating donor (primate model)
Principal Investigator
KONDO Takashi
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
Institute of Development, Aging and Cancer, Tohoku University
Co-operative Research on Clinical Application of Heart and Heart-Iung Transplantation
Principal Investigator
FURUSE Akira
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Thoracic surgery
Research Institution
University of Tokyo
A Study of the Safe and Raliable Monitoring Method of Lung Allograft Rejection in Primate Model.
Principal Investigator
Principal Investigator
FUJIMURA Sigefumi
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
Gene Aberration of Early Lung Cancer and Borderline Lesions of Bronchus (subtitle : especially in HPV infection, oncogene and tumor supperssor gene)
Principal Investigator
SAITO Yasuki
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Institute of Development, Aging and Cancer, Tohoku University
Co-operative research for the establishment of the presservation and the maintenance of the functional integrity in pulmonary and cardiopulmonary transplantation.
Principal Investigator
Principal Investigator
FUJIMURA Shigehumi
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Thoracic surgery
Research Institution
Institute of Development, Aging and Cancer, Tohoku University
STUDY OF PRESERVATION AND EARLY DIAGNOSIS OF REJECTION IN A MODEL OF PRIMATE LUNG ALLOTRANSPLANTATION
Principal Investigator
Principal Investigator
FUJIMURA Sigefumi
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
CoーOperative Study for Clinical Application of Lung and Heart-Lung Transplantation
Principal Investigator
HAYATA Y
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Thoracic surgery
Research Institution
Tpkyo Medical College, Faculty of Medicine
Lung Transplantation Using Primates Aiming Its Clinical Application.
Principal Investigator
Principal Investigator
FUJIMURA Shigefumi,
仲田 祐
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
# of Projects (Dsc)
# of Projects (Asc)
1.
SATO Masami
(30250830)
# of Collaborated Projects :
9results
# of Collaborated Products :
0results
2.
MATSUDA Hikaru
(00028614)
# of Collaborated Projects :
6results
# of Collaborated Products :
0results
3.
KONDO Takashi
(10195901)
# of Collaborated Projects :
6results
# of Collaborated Products :
0results
4.
KOYANAGI H
(90138884)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
5.
FURUSE A
(70010163)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
6.
SAGAWA Motoyasu
(70292274)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
7.
ONO Sadafumi
(80250827)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
8.
TANITA Tatsuo
(20217144)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
9.
SAITO Yasuki
(90153824)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
10.
MATSUMURA Yuji
(80281997)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
11.
TOMITA M
(70039808)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
12.
HANDA Masashi
(70211498)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
13.
KATO Harufumi
(20074768)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
14.
TABAYASHI Koichi
(90142942)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
15.
TAKAMOTO Shin-ichi
(60137833)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
16.
TANABE T
(50000956)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
17.
KOMATSU Sakuzou
(00045329)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
18.
YAZAKI Yoshio
(20101090)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
19.
KAIHARA Shigekoto
(30010234)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
20.
SHIRATO Kunio
(80004761)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
21.
SAITO Ryo
(70225689)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
22.
ISOBE Mitsuaki
(80176263)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
23.
YASUI Hisataka
(20089923)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
24.
HAYATA Y
(30074470)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
25.
NAMIKAWA Syoji
(50024716)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
26.
NAKAJIMA Jun
(90188954)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
27.
AKADA Shintaro
(30028609)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
28.
MOMMA Kazuo
(80075233)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
29.
KATO Hirohisa
(30080724)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
30.
AYABE Hiroyosi
(60128147)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
31.
KYO Shunei
(30153232)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
32.
KITAMURA Soichiro
(10028607)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
33.
草川 實
(10046336)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
34.
毛利 平
(60108503)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
35.
人見 滋樹
(80173186)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
36.
仲田 祐
(20006068)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
37.
川島 康生
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
38.
神谷 哲郎
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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