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FUJIMURA S
藤村 重文
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Alternative Names
藤村 重又 フジムラ シゲマミ
FUJIMURA Sigefumi 藤杆 重文
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Researcher Number
40006078
External Links
Affiliation (based on the past Project Information)
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1999: 東北大学, 加齢医学研究所, 所長
1993 – 1999: Institute of Development, Aging and Cncer, Tohoku University. Professor, 加齢医学研究所, 教授
1997: Tohoku University, Institute Development, Aging and cancer Professor, 加齢医学研究所・呼吸器研究分野, 教授
1996: Insitute of Development, Aging and Cancer, Tohoku University Department of Thora, 加齡医学研究所, 教授
1996: 東北大学, 加齢医学研究所呼吸器再建研究分野, 教授
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1995: 東北大学, 加齢医学研所・呼吸器再建研究分野, 教授
1992: RESEARCH INSTITUTION FOR CHEST DISEASE AND CANCER:DEPARTMENT OF SURGERY:PROFESSOR, 抗酸菌病研究所外科部門, 教授
1989 – 1992: Res. Ins. for Chest Dis. and Cancer Dep. of Surgery, Professor, 抗酸菌病研究所, 教授
1987 – 1988: 東北大学, 抗酸菌病研究所, 助教授
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Review Section/Research Field
Principal Investigator
Thoracic surgery
Except Principal Investigator
Thoracic surgery
Keywords
Principal Investigator
肺移植 / 拒絶反応 / 肺保存 / Lung transplantation / 心肺移植 / 拒絶反応監視 / Lung Transplantation / Heart-Lung Transplantation / Pulmonary Preservation / Immunosuppression
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More
/ 免疫抑制 / 肺水腫 / 心停止ドナー / Rejection Monitoring / Non-Heart-Beating Donor / 気管支鏡 / soluble form CD44 / 接着因子 / 肺癌 / 転移 / 腫瘍マーカー / in situ PCR / K-ras / 点突然変異 / PCR / in situ hybridization / 嚢胞性肺疾患 / 気胸 / 家系内発生疾患 / リンゲージ解析 / 遺伝子異常 / リンケージ解析 / 霊長類 / 臨床応用 / 保存移植肺機能 / Ep4液 / 日本猿肺移植 / 心肺保存 / Lung preservation / Primate / Clinical application / Function of preserved lung / Ep4 solution / 保存 / 徐神経 / 肺および心肺保存 / 保存臓器の評価 / 拒絶反応診断法 / 免疫抑制剤 / 移植後病態生理 / 移植適応基準 / LUNG TRANSPLANTATION / CARDIO-PULMONARY TRANSPLANTATION / PRESERVATION / DENERVATION / REJECTION / IMMUNOSUPPRESSION / PULMONARY EDEMA / 胸腔鏡 / 肺五検 / 肺生検 / rejection / Monitoring of rejection / Thoracoscopic procedure / Lung biopsy / トレランス / ラットモデル / Th1サイトカイン / Th2サイトカイン / 脾細胞移植 / 免疫組織染色 / 免疫阻害 / ラット / 肺胞水分クリアランス / 肺胞上皮機能 / 副腎皮質ホルモン / 適応拡大 / 肺・心肺保存 / 移植後肺水腫 / Reection Monitoring / Non-Heart-Beatig Donor / 拒絶反応診断 / 気管支粘膜血流 / サルモデル / レーザー組織血流計 / 気管支粘膜血流量 / 気管支擦過 / 気管支肺胞洗浄 / lung transplantation / allograft rejection / bronchofiberscope / Bronchial mucosal blood flow / サル肺移植 / 気管支肺胞洗浄液 / リンパ球分画 / リンパ球自然芽球化反応 / Primate lung transplantation / Bronchoalveolar lavage fluid / Immunological monitoring / Bronchofiberscope / Lymphocyte subset
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More
Except Principal Investigator
PCR / 肺移植 / 肺傷害 / in situ hybridization / 心臓移植 / PCR-SSCP / 発癌 / 心筋症 / 免疫抑制療法 / donation / Immunosuppression / 好中球 / 血管内皮細胞 / 肺胞上皮細胞 / 慢性肺気腫 / イオントランスポート / 細胞培養 / 胸部X線無所見肺癌 / 癌抑制遺伝子p53 / 免疫染色 / roentgenographically occult lung cancer / tumor supperssor gene p53 / immunohistostain / 臓器移植ネットワーク / 抗接着抗体 / 異種心臓移植 / Cardiac xenotransplantation / Lung Transplantation / Non-Heart-Beating Donor / 遺伝子導入 / 異種心移植 / 補助人工心臓 / 肺保存 / 慢性拒絶反応 / in situ PCR / K-ras / 点突然変異 / direct in situ PCR / point mutation / 肺胞水分クリアランス / 心肺移植 / LUNG TRANSPLANTATION / enriched PCR / protein kinase C / transendothelial electrical resistance / 開胸術 / 胸水 / G-CSF / 開胸術後肺傷害 / 術後胸水 / 好中球遊走化因子 / 移植 / プロテインキナーゼC / 細胞内信号伝達系 / 肺上皮・血管内皮細胞移植 / 腫瘍血管新生 / 血管新生抑制治療 / Dormant therapy / 血管新生 / 血管新生抑制剤 / dormancy therapy / non-cytotoxic agent / adjuvant therapy / lung cancer / 肺・心肺保存 / ラット,犬,ニホンザル肺移植 / 心停止後肺保存 / 阻血再潅流障害 / 早期拒絶反応モニタリング / 肺胞洗浄液(BALF) / 免疫抑制剤 / 気管支吻合部創治癒 / reimplantation response / 肺胞洗浄液 / Ca拮抗剤 / 拒絶反応の診断 / 抗酸化剤 / 気管支吻合部血流 / Lung and heart-lung transplantation / Lung transplantation in rats, dogs and monkey / Reperfusion injury / Monitoring of early rejection / BALF / Immunosuppressive agents / Wound healing of bronchial anastomotic site / Lung preservation after cardiac arrest / HPV感染 / PCR‐SSCP / P53 / 原発性肺癌 / ヒトパピローマウイルス(HPV) / 肺門部早期肺癌 / HPV infection / サイトメガロウィルス / doration / donor / 抗CD2抗体 / 抗ICAM-1抗体 / Heart Transplantation / Organ transplantation network / Cytomegalo virus / Cardiomyopathy / Anti-adhesion molecule-antibody / PCR-SSCP法 / アポトーシス関連遺伝子bc1-2 / アポトーシス / TUNEL法 / p21蛋白 / PCP-SSCP法 / アポトーシス関連遺伝子bcl-2 / 肺扁平上皮癌 / p53 / 癌抑制遺伝子 / 多発癌 / 増殖動態 / bcl-2 / apoptosis / TUNEL method / cdk inhibitor p21 / 心停止ドナー / 両側肺移植 / Bilateral Lung Transplantation / 心移植 / グラフト動脈硬化症 / dination / 渡航心移植 / 冠動脈硬化症 / Donation / 移植心冠状動脈硬化 / donor臓器 / Heart Transp lantation / Organ transp lantation network / Graft atherosclerosis / Cardiomyoathy / gene transfer / in situ bridization / indirect in situ PCR / K-RAS / 早期肺癌 / 遺伝子異常 / 肺癌 / 癌関連遺伝子 / 低酸素 / 摘出灌流肺 / 肺血管透過性 / 接着因子 / 摘出潅流肺 / Acute lung injury / Hypoxia / Pulmonary vascular permeability / Isolated lung / Polymorphonuclear leukocytes / Adgesion molecule / Myeloperoxidase / 肺細胞移植 / 肺保存液 / ステロイド / 肺障害 / 肺胞II型上皮細胞 / enzymatic tissue digestion法 / difference adherence法 / Na+-K+-ATPase / 無機リン / Chronic pulmonary emphysema / alveolar epithelial cells / Ion transport / Pulmonary cell preservation / Lung injury / Cell culture / Lung preservation medium / Steroid / 小児 / 脳死判定 / 異種移植 / 小児心臓移植 / 小児肺-心臓移植 / 適応基準 / 先天性心疾患 / 肺高血圧 / 小児脳死判定基準 / Eisenmenger症候群 / HEART TRANSPLANTATION / HEART-LUNG TRANSPLANTATION / CHILDREN / DETERMINATION OF BRAIN DEATH / XENOTRANSPLANTATION / 肺水腫 / 肺胞上皮機能 / 副腎皮質ホルモン / Heart-Lung Transplantation / Pulmonary Preservation / Rejection Monitoring / 移植術後管理 / 移植臓器機能保存 / 急性拒絶反応 / 早期診断 / 遺伝子治療 / 拒絶反応 / 臨床応用 / 患者管理 / 臓器機能維持 / 転写因子 / 虚血再灌流障害 / ドナー心機能 / Heart transplantation / Lung transplantation / Ischemia-reperfusion injury / rejection / gene transfer therapy / early detection of rejection / left ventriular assist device / clinical study / Enriched PCR / mutation enrichment / ras / DNA ポリメラーゼ / K-ras 遺伝子 / 活性化好中球 / 細胞内信号伝達経路 / アクチン / 内皮細胞 / 接着分子 / 細胞骨格 / シグナル伝達回路 / ICAM-1 / PECAM / シグナル伝達経路 / LUNG INJURY / ACTIVATED NEUTROPHILS / Intracellul signal transduction / vascular endothelial cells. / actin
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Research Projects
(
28
results)
Co-Researchers
(
38
People)
Project Start Year (Newest)
Project Start Year (Oldest)
低毒性の血管新生抑制剤の再発見-新しい戦略での肺癌術後治療臨床試験を目指して-
Principal Investigator
佐川 元保
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
嚢胞性肺疾患家系のリンケージ解析
Principal Investigator
Principal Investigator
藤村 重文
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
Studies on management of heart transplant recipients and maintenance of donor organs
Principal Investigator
TAKAMOTO Shinichi
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (A).
Research Field
Thoracic surgery
Research Institution
University of Tokyo
Detection of 1 mutant cell in normal 10^5〜10^6 cells : Genetic diagnosis using enriched PCR
Principal Investigator
SAGAWA Motoyasu
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Thoracic surgery
Research Institution
Tohoku University
STUDY OF ADHESION MOLECULES, CYTOSKELETON AND SIGNAL TRANSDUCTION PATHWAY ON INJURY OF ENDOTHELIAL CELLS FOR ISOLATED PRESERVED LUNGS
Principal Investigator
TANITA Tatsuo
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
Bronchial brushing as an early diagnostic method for lung allograft rejection in primate lung transplant mo
Principal Investigator
Principal Investigator
MATSUMURA Yuji
, 藤村 重文
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Thoracic surgery
Research Institution
Tohoku University
in situ PCR法による肺癌発癌過程における遺伝子異常局在の病理学的な解明
Principal Investigator
Principal Investigator
藤村 重文
Project Period (FY)
1997
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
開胸術後に肺傷害をもたらす胸腔内炎症の発生機序の解析と制御に関する研究
Principal Investigator
ONO Sadafumi
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
肺血管内皮細胞及び肺胞上皮細胞の移植による慢性肺気腫の治療法に関する基礎研
Principal Investigator
谷田 達男
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
MULTI-CENTER STUDIES FOR CLINICAL APPLICATION OF PEDIATRIC HEART AND LUNG TRANSPLANTATION IN JAPAN
Principal Investigator
MATSUDA Hikaru
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
OSAKA UNIVERSITY
Research Project on the Clinical Indication in Japan and the Posttransplant Patient Management in Lung and Heart-Lung Transplantation.
Principal Investigator
Principal Investigator
FUJIMURA Shigefumi
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
Experimental study on the assessment of lung preservation from the stand point of the alveolar type II epithelial cell function
Principal Investigator
KONDO Takashi
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
血中可溶性接着因子の肺癌血行性転移における意義
Principal Investigator
Principal Investigator
藤村 重文
Project Period (FY)
1996
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Thoracic surgery
Research Institution
Tohoku University
Study of tolerance mechanism in a functional tolreance modrl of rat lung transplant
Principal Investigator
Principal Investigator
FUJIMURA Shigefumi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Tohoku University
A study for pulmonary cell preservation and lung transplantation on functions of alveolar epithelial ion transport
Principal Investigator
TANITA Tatsuo
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Tohoku University
Co-operative Research on Clinical Application and Functional Preservation of Heart and Heart-lung Transplantation
Principal Investigator
NAKAJIMA Jun
,
古瀬 彰
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
University of Tokyo
Assessment of genetic changes in the carcinogenesis of squamous cell lung cancer using in situ PCR.
Principal Investigator
SATO Masami
,
斎藤 泰紀
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Tohoku University
ACUTELUNG INJURY INDUCED BY HYPOXA IN RATS
Principal Investigator
ONO Sadafumi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Thoracic surgery
Research Institution
Tohoku University
Research Project to Establish the Clinical Indication and the Way for Safe Management of the Graft in Lung and Heart-Lung Transplantation.
Principal Investigator
Principal Investigator
FUJIMURA Shigefumi
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
Tohoku University
Genetical analasys of genesis of multiple primary squamous cell carcinoma of lung
Principal Investigator
SATO Masami
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Tohoku University
Study in possibility of lung transplantation from non-heart beating donor (primate model)
Principal Investigator
KONDO Takashi
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Thoracic surgery
Research Institution
Institute of Development, Aging and Cancer, Tohoku University
Co-operative Research on Clinical Application of Heart and Heart-Iung Transplantation
Principal Investigator
FURUSE Akira
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Thoracic surgery
Research Institution
University of Tokyo
A Study of the Safe and Raliable Monitoring Method of Lung Allograft Rejection in Primate Model.
Principal Investigator
Principal Investigator
FUJIMURA Sigefumi
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
Gene Aberration of Early Lung Cancer and Borderline Lesions of Bronchus (subtitle : especially in HPV infection, oncogene and tumor supperssor gene)
Principal Investigator
SAITO Yasuki
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
Institute of Development, Aging and Cancer, Tohoku University
Co-operative research for the establishment of the presservation and the maintenance of the functional integrity in pulmonary and cardiopulmonary transplantation.
Principal Investigator
Principal Investigator
FUJIMURA Shigehumi
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Thoracic surgery
Research Institution
Institute of Development, Aging and Cancer, Tohoku University
STUDY OF PRESERVATION AND EARLY DIAGNOSIS OF REJECTION IN A MODEL OF PRIMATE LUNG ALLOTRANSPLANTATION
Principal Investigator
Principal Investigator
FUJIMURA Sigefumi
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
CoーOperative Study for Clinical Application of Lung and Heart-Lung Transplantation
Principal Investigator
HAYATA Y
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Thoracic surgery
Research Institution
Tpkyo Medical College, Faculty of Medicine
Lung Transplantation Using Primates Aiming Its Clinical Application.
Principal Investigator
Principal Investigator
FUJIMURA Shigefumi,
仲田 祐 (中田 祐)
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Thoracic surgery
Research Institution
TOHOKU UNIVERSITY
# of Projects (Dsc)
# of Projects (Asc)
1.
SATO Masami
(30250830)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
2.
MATSUDA Hikaru
(00028614)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
3.
KONDO Takashi
(10195901)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
4.
KOYANAGI H
(90138884)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
5.
FURUSE A
(70010163)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
6.
SAGAWA Motoyasu
(70292274)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
7.
ONO Sadafumi
(80250827)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
8.
TANITA Tatsuo
(20217144)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
9.
SAITO Yasuki
(90153824)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
10.
MATSUMURA Yuji
(80281997)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
11.
TOMITA M
(70039808)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
HANDA Masashi
(70211498)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
13.
KATO Harufumi
(20074768)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
14.
TABAYASHI Koichi
(90142942)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
15.
TAKAMOTO Shin-ichi
(60137833)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
TANABE T
(50000956)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
KOMATSU Sakuzou
(00045329)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
YAZAKI Yoshio
(20101090)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
19.
KAIHARA Shigekoto
(30010234)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
20.
SHIRATO Kunio
(80004761)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
21.
SAITO Ryo
(70225689)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
22.
ISOBE Mitsuaki
(80176263)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
23.
YASUI Hisataka
(20089923)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
24.
HAYATA Y
(30074470)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
NAMIKAWA Syoji
(50024716)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
NAKAJIMA Jun
(90188954)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
AKADA Shintaro
(30028609)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
MOMMA Kazuo
(80075233)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
KATO Hirohisa
(30080724)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
AYABE Hiroyosi
(60128147)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
KYO Shunei
(30153232)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
KITAMURA Soichiro
(10028607)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
草川 實
(10046336)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
毛利 平
(60108503)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
人見 滋樹
(80173186)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
仲田 祐
(20006068)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
川島 康生
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
神谷 哲郎
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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