NAKAJIMA Katuhisa 中島捷久

… Alternative Names

NAKAJIMA Katsuhisa 中島捷久

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Researcher Number	40012778
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Affiliation (based on the past Project Information) *help	2008: 名古屋市立大学, 大学院医学研究科, 教授 2007 – 2008: 名古屋市立大学, 大学院・医学研究科, 教授 2006: Nagoya City University, Graduate School of Medical Sciences, Professor, 大学院医学研究科, 教授 2002 – 2005: Nagoya City University Graduate School of Medical Sciences Professor, 大学院・医学研究科, 教授 1992 – 2001: 名古屋市立大学, 医学部, 教授 … More 1994: Nagoya City University, School of Medicine, Professor, 医学部・ウィルス学教室, 教授 1994: 名古屋市立大学, 医学部・ウイルス学教室, 教授 1988 – 1990: 東京大学, 医科学研究所, 助教授 1986: Institute of Medical Science, University of Tokyo, Associate Professor, 医科学研究所, 助教授 1986: The Institute of Medical Science, The University of Tokyo Associate Professor, 医科学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator Virology / Virology Except Principal Investigator Virology / Otorhinolaryngology / Otorhinolaryngology / 分子遺伝学・分子生理学
Keywords	Principal Investigator インフルエンザウイルス / Influenza virus / 血球凝集素 / hemagglutinin / Receptor Specificity / Receptor Binding Site / Amino Acid Sequence of Ha / Influenza a Virus / シアル酸結合部位 / シグナルペプチド … More / レセプタ-結合領域 / 部位突然変異 / レセプタ-特異性 / レセプタ-結合構造 / HAのアミノ酸配列 / インフルエンザウイルスA型 / Expression of HA protein / 部位突然変異法 / HA蛋白の発現 / evolution / protein / amino acid change / アミノ酸変異地図 / ランダム変異 / HA / インフルエンザ / 抗原変異 / 進化 / 蛋白質 / アミノ酸変異 / desialidation / neuraminidase / HA protein / virion formation / インフルエンザウィルス / GG167 / 脱シアル酸反応 / ノイラミニダーゼ / HA蛋白質 / 粒子形成 / substantia nigra / immunohistochemical / neuron / intranasal inoculation / neurovirulence / シアル酸 / 脳細胞 / ラット / レセプター / 黒質 / 免疫化学 / 神経 / 経鼻接種 / 神経病原性 / in vitro antibody synthesis / monoclonal antibody / Influenza Virus / in vitro発現 / in vitro抗体作製 / 単一抗体 / ミミック抗原 / インフルエンザワクチン / 抗原 / ファージディスプレイ … More Except Principal Investigator PCR / 単純ヘルペスウイルス1型 / 顔面神経麻痺 / インフルエンザウイルス / RNA / LacZ / HSV-1 / Bell麻痺 / 再活性化 / HAタンパク質 / Genome structure / Replication of RNA / Viroid / Viral RNA / cDNAクローン / 遺伝子構造 / RNAの複製 / ウイロイド / ウイルスRNA / hepato growth factor / edaravone / steroid / herpes simplex virus type 1 / facial nerve palsy / 治療 / 病因・病態 / 早期診断 / Hunt症候群 / 神経栄養因子 / エダラボン / ステロイド / Eustachian tube / Adenovirus / H. influenzae / recurrent otitis media / Intractable otitis media / 耳管 / アデノウィルス / インフルエンザ菌 / 反復性中耳炎 / 難治性中耳炎 / reactivation / Bell's palsy / Facial nerve paralysis / 神経内圧 / 神経血流 / リント症候群 / ベル麻酔 / ウイルス感染細胞 / 免疫操作 / 神経障害 / ベル麻痺 / hemagglutinin / receptor / influenza virus / レセプター結合特異性 / 血球凝集能 / インフルエンザウィルス / 血球凝集素 / レセプター / Antigenic determinant site / HA protein / Influenza virus / Multipin peptide synthesis / HAタンパク / 抗原決定基 / マルチピン合成法 / 固相法ペプチド合成法 / 肝細胞増殖因子 / HSVベクター / 糖尿病 / 単純ヘルペスウィルスI型 / フリーラジカル / HGF / HSV / マウスモノクローナル抗体 / ELISA / ヒト回復期血清 / 連続配列エピトープ / スポット合成法 / モノクローナル抗体 / H3N2ウイルス / インフルエンザ / 分子生物学 / ウイルス宿主相互作用 / ウイルス持続感染 / ウイルス変異 / ウイルスゲノム / ウイルストロピズム / ウイルス病原性 Less

Basic research for pathology and new therapy of HSV-induced facial nerve palsy
- Principal Investigator
  
  MURAKAMI Shingo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University
Precise cliagnosis and treatment of facial nerve palsy(Bell's palsy and Ramsay hunt syndrome)
- Principal Investigator
  
  MURAKAMI Shingo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  NAGOYA CITY UNIVERSITY
ファージディスプレイ法によるミミック抗原の作製とインフルエンザワクチンの開発研究Principal Investigator
- Principal Investigator
  
  中島捷久
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
The analysis of the restriction of amino acid substitution on the hemagglutinin molecule of influenza A virusPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  NAGOYA CITY UNIVERSITY
Pathophysiology and Mechanism of Bell's Palsy ; Early Diagosis and Treatment.
- Principal Investigator
  
  SHINGO Murakami
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University
Experimental studies of prevention and therapy in intractable otitis media
- Principal Investigator
  
  OZEKI Masashi, 宮本直哉
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University
molecular basis for the virion formation of influenza virusPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
The study on the molecular basis for neurovirulence of influenza virus.Principal Investigator
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
MOLECULAR BASIS OF NOVEL RECEPTOR BINDING SPECIFICITY OF RECENT ISOLATES OF HUMAN INFLUENZA A VIRUSES
- Principal Investigator
  
  NOBUSAWA Eri
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  NAGOYA CITY UNIVERSITY
マウスとヒトの抗体が認識するインフルエンザウイルス抗原決定基の比較解析
- Principal Investigator
  
  NAKJIMA Setsuko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  国立公衆衛生院
Analysis of antigenic determinant sites of influenza virus using epitope scanning method
- Principal Investigator
  
  NAKAJIMA Setsuko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The Institute of Public Health
The study of the production of human antibody in vitro expression system and recognition of epitope on the HA protein by human immune system.Principal Investigator
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
「ウイルス病原性の分子的基盤」研究推進のための調査研究
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
The Analysis of the Structure of Receptor Binding Site of Hemagglutin in Molecule of Influenza A Virus and of the Characteristics of Receptor.Principal Investigator
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
The study of the antigenic and sialic acid binding sites on the hemagglutinin molecule of influenza virus by recombinant DNA technique.Principal Investigator
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The Institute of Medical Science, The University of Tokyo
Structure and Function of Self-replicate RNAs
- Principal Investigator
  
  OKADA Yoshimi
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  University of Tokyo

All 2005 2004 2003

All Journal Article

[Journal Article] Accumulation of amino acid substitution promotes irreversible structural changes In the hemagglutinin of human influenza AH3 virus during evolution2005
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  J.Virol (in press)
- Data Source
  KAKENHI-PROJECT-15659111
[Journal Article] Accumulation of amino acid substitution promotes irreversible structure changes in the hemagglutinin of human influenza AH3 virus during evolution2005
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  J.Virol (in press)
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Accumulation of amino acid substitutions promotes irreversible structural changes in the hemagglutinin of human influenza AH3 Virus during evolution2005
- Author(s)
  Katsuhisa Nakajima et al.
- Journal Title
  
  J.Virol. 79
  
  Pages: 6472-6477
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Influence of additional acylation site(s) of influenza B virus hemagglutinin on syncytium formation2005
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  Microbiol.Immu. (in press)
- NAID
  10015527889
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Accumulation of amino acid substitution promotesirreversible structural changes in the hemagglutinin of human influenza AH3 virus during evolutio2005
- Author(s)
  Katsuhisa Nakajima, Eri Nobusawa, Alexander Nagy, Setsuko Nakajima
- Journal Title
  
  J. Virol. 79
  
  Pages: 6472-6477
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Influence of additional acylation site(s) of influenza B virus hemagglutinin on syncytium formation2005
- Author(s)
  Ujike M., Nakajima K., Nobusawa E.
- Journal Title
  
  Microbiol. Immun. (in press)
- NAID
  10015527889
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Amino-acid change on the antigenic region B1 of H3 haemagglutinin may be a trigger for the emergence of drift strain of influenza A virus2004
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  Epidemiol.Infect. 132
  
  Pages: 399-406
- Data Source
  KAKENHI-PROJECT-15659111
[Journal Article] Influence of acylation sites of influenza B virus HA on fusion poreformation and dilation2004
- Author(s)
  Ujike M, Nakajima K., Nobusawa E.
- Journal Title
  
  J. Virol. 78
  
  Pages: 11536-11543
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Amino-acid change on the Antigenic region B1 of H3 hemagglutinin may be a trigger for the emergence of drift strain on influenza A virus2004
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  Epidemiol.Infect 132
  
  Pages: 399-406
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Influence of acylation sites of influenza B virus HA on fusion pore formation and dilation2004
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  J.Virol 78
  
  Pages: 11536-11543
- Data Source
  KAKENHI-PROJECT-15659111
[Journal Article] Influence of acylation sites of influenza B virus HA on fusion pore-formation and dilation2004
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  J.Virol. 78
  
  Pages: 11536-11543
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Amino-acid change on the antigenic region B1 of H3 haemagglutinin may be a trigger for the emergence of drift strain of influenza A virus2004
- Author(s)
  Sato, K., Morishita, T., Nobusawa, E., Tonegawa, K.Sakae, K., Nakajima, S., Nakajima, K.
- Journal Title
  
  Epidemiol. Infect 132
  
  Pages: 399-406
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Restriction of amino acid change in influenza A virus H3HA2003
- Author(s)
  Nakajima K. et al.
- Journal Title
  
  J.Virol 77
  
  Pages: 10088-10098
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Restriction of amino acid change in influenza A virus H3HA: comparison of amino acid changes observed in nature and in vitro2003
- Author(s)
  Nakajima K, Nobusawa E, Tonegawa K, Nakajima S
- Journal Title
  
  J. Virol 77
  
  Pages: 10088-10098
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104

1. NAKJIMA Setsuko (80124402)

# of Collaborated Projects: 8 results

# of Collaborated Products: 11 results
2. NOBUSAWA Eri (90183904)

# of Collaborated Projects: 7 results

# of Collaborated Products: 12 results
3. MURAKAMI Shingo (80157750)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OZEKI Masashi (80315887)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. IIDUKA Narusi (30222821)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NOMOTO Akio (70112670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NISHINO Hitoo (60073730)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 宮本直哉 (90219816)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. HAMAJIMA Yuki (30343403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HIDA Hideki (00305525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. WATANABE Nobuhiro (90285221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUZUKI Motohiko (50326138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OKADA Yoshimi (30011703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHIBUTA Hiroshi (70012721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ISHIHAMA Akira (80019869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SHIKATA Eishiro (00001389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 永井美之 (20022874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 西山幸廣 (60115615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 田代真人 (90111343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 小塚諭 (40117817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAJIMA Katuhisa 中島 捷久

NAKAJIMA Katsuhisa 中島 捷久

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ファージディスプレイ法によるミミック抗原の作製とインフルエンザワクチンの開発研究Principal Investigator

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The analysis of the restriction of amino acid substitution on the hemagglutinin molecule of influenza A virusPrincipal Investigator

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molecular basis for the virion formation of influenza virusPrincipal Investigator

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The study on the molecular basis for neurovirulence of influenza virus.Principal Investigator

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The study of the production of human antibody in vitro expression system and recognition of epitope on the HA protein by human immune system.Principal Investigator

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The Analysis of the Structure of Receptor Binding Site of Hemagglutin in Molecule of Influenza A Virus and of the Characteristics of Receptor.Principal Investigator

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NAKAJIMA Katuhisa 中島捷久

NAKAJIMA Katsuhisa 中島捷久