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KAI Yasushi  甲斐 泰

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Researcher Number 40029236
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2007: Fukui University, of Technology, Department of Environmental and Biotechnological Frontier Engineering, Professor
2006: 大阪大学, 大学院工学研究科, 教授
1998 – 2005: 大阪大学, 大学院・工学研究科, 教授
2000 – 2001: 大阪大学, 工学研究科, 教授
1998: 大阪大学, 工学研究科, 教授 … More
1993 – 1997: 大阪大学, 工学部, 教授
1986 – 1992: 大阪大学, 工学部, 助教授
1988: 大阪化学, 工学部, 助教授 Less
Review Section/Research Field
Principal Investigator
工業物理化学 / Structural biochemistry
Except Principal Investigator
結晶学 / Biological Sciences / Structural biochemistry / Chemistry related to living body / Biophysics
Keywords
Principal Investigator
結晶構造 / X線構造解析 / 固相反応 / PEPC-Protein Kinase / 炭酸固定酵素 / 銅蛋白質 / ジオレフィン化合物 / ジアセチレン化合物 / 立体選択的反応 / 分子性結晶 … More / PEPC-PK / C4 plant / 分子機構解明 / 活性調節因子 / PEPカルボキシラーゼ / トウモロコシ / C4植物 / RuBisCo / 蛋白質の結晶化 / X線結晶構造解析 / 結晶構造解析 / ブルー銅蛋白質 / アズリン / 結晶化 / 金属酵素 / 金属蛋白質 / 合成脂質 / 原子価拡張性化合物 / PEPC mutant K620S / NADP-denendent malic enzyme / Structure-function relation / Mechanism of regulation / Phosphoenolpyruvate carboxylase / 炭酸固定酸素 / PEPC変異体K620S / NADP依存型リンゴ酸酵素 / 構造-機能相関 / 活性調節メカニズム / ホスホエノールピルビン酸カルボキシラーゼ / Molecular mechanism / X-ray analysis / Effector / PEP carboxylase / Carboxylase / Maize / PROTEIN CRYSTALLIZATION / PROTEIN COMPLEX / RAPID X-RAY DIFFRACTOMETER / RUBISCO / CARBOXYLASE / X-RAY CRYSTAL STRUCTURE ANALYSIS / 迅速X線回析計 / 蛋白質複合体 / 迅速X線回折計 / ルビスコ / crystal engineering / dynamic structure / time-resolved structure analysis / rapid X-ray structure analysis / phase transition / crystal structure / solid state reaction / organic crystal / 結晶構造予測 / 動的反応解析 / 動的構造解析 / 高温相の構造 / フォトクロミズム / 2次元結晶 / 分子配列 / 試料低温装置 / 光照射下での固相反応 / 特殊条件下での構造解析 / 結晶工学 / 動的構造 / 時間分割構造解析 / 迅速X線構造解析 / 相転移 / 有機結晶 / reflection-intensity-measurement / phosphoenolpyrubicacidcarboxylase (PEPC) / 2.0 A resolution / spinach / CO_2-fixation enzymes / X-ray structure analysis / リブロースビスリン酸カルボキシラーゼ / 二酸化炭素固定 / 反射強度測定 / ホスホエノールピルビン酸カルボキシラーゼ(PEPC) / 2.0A分解能 / ホウレンソウ / 二酸化炭素固定化酵素 / 三次元立体構造 / シンクロトロン放射光 / PEPC / 耐酸性 / スタッキング / シダ植物 / 分子進化 / 構造機能相関 / プラストシアニン / 電子伝達 / シュードアズリン / 構造解析ラボシステム / ヘム蛋白質 / ピエゾクロミズム / 液晶相反応 … More
Except Principal Investigator
X線構造解析 / 分子設計 / 分子性結晶 / X線結晶構造解析 / 構造解析 / 反応制御 / 固体反応 / X線結晶解析 / Streptomyces caespitosus / 反応機構 / 構造精密化 / S100b / カルシウム結合タンパク質 / ウシ脳 / 固相反応 / X-ray Crystal Structure Analysis / Crystallization of Proteins / 精密回折データの測定 / 精密回析データの測定 / 蛋白質の結晶化 / Solid-state Reactions / Molecular Mechanics / Inclusion Compounds / Surface Structures / Chiral Reactins / X-ray Crystal Stuctures / Molecular Design / 反応立体経路 / 分子力場 / 包接化合物 / 表面構造 / 不斉反応 / X線結晶構造 / X-ray structure analysis / drug design / infectious desease / Plasmodium falciparum / ドラッグデザイン / 感染症 / 熱帯熱マラリア / sleep / allergy / enzyme inhibitor / X-ray'crystallography / Th2 cytokine / eosinophil / transgenic mouse / prostaglandin D2 / 肥満細胞 / 睡眠 / アレルギー / 酵素阻害剤 / 結晶構造解析 / Th2サイトカイン / 好酸球 / トランスジェニックマウス / プロスタグランジンD2 / regulation by phosphorylation / allosteric regulation mechanism / enzyme reaction mechanism / site-directed mutagenesis / protein engineering / X-ray crystallography / phosphoenolpyruvate carboxylase / CO_2-fixation enzyme / 部位特異的変異 / C4光合成 / ホスホエトルピルビン酸カルボキシラーゼ / トウモロコシ / 大腸菌 / リン酸化による活性調節 / アロステリック活性調節機構 / 酵素反応機構 / 部位特異的変異導入 / タンパク質工学 / ホスホエノールピルビン酸カルボキシラーゼ / 炭酸固定酵素 / solid state photoreaction / molecular movement in crystal / crystal chemistry / enantioselective reaction / solid state reaction / organic solid state chemistry / 研究業績集 / 講演要旨集 / 評価班 / 特別シンポジウム / 国際会議 / 不斉認識 / 固相有機化学反応 / パネル討論会 / 国際研究集会 / 総括班会議 / 班員間の連絡 / ニュースレター / 班会議 / 公開シンポジウム / 固体光反応 / 結晶中の分子移動 / 結晶化学 / 不斉選択的反応 / 有機固体化学 / 固体表面 / 無溶媒有機合成反応 / 熱反応 / 光反応 / 研究業績 / X-ray crystal structure analysis / metalloprotease / protease / Streptomayces caespitosus / 金属プロテアーゼ / プロテアーゼ / 重点領域研究の準備 / 分子静結晶の反応 / 反応機構を解明 / 中間体構造 / チオレドキシンペルオキシダーゼ / 超分子複合体 / NADPH複合体 / フラビン蛋白質 / 駆虫剤 / プロスタグランジン / シャーガス病 / リーシュマニア症 / アフリカ睡眠病 / 阻害剤開発 / PGF_<2α> / プロスタグランジンF合成酵素 / 異常分散法 / セレノメチオニン / TATA-binding protein (TBP) / 転写反応抑制因子 / TBP-interacting protein / Thermococcus kodakaraensis KOD1 / 超好熱始原菌 / ホロ体 / ダイマー / 反応設計 / 結晶環境下 / 分子認識解析 / 動的特性解析 / 結晶構造予測 / 動的構造解析 / 有機結晶工学 / 成果とりまとめ / 反応の制御 / 反応の解析 / 研究成果公開 / 有機固体反応 Less
  • Research Projects

    (31 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (33 People)
  •  超原子価硫黄原子を有する超分子複合体蛋白質による過酸化水素還元反応の制御機構解明

    • Principal Investigator
      井上 豪
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Development ofenzyme inlulkar far infectious diseace including malaria and clarification ofthe inlubitor activity

    • Principal Investigator
      INOUE Tsuyoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Osaka University
  •  寄生虫由来プロスタグランジンF合成酵素の阻害剤開発とその作用機構の解明

    • Principal Investigator
      井上 豪
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Structural biology of C4 enzymes related in regulation of phosphoenolpyruvate carboxylasePrincipal Investigator

    • Principal Investigator
      KAI Yasushi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University
  •  超好熱始原菌由来転写関連因子TIPの転写調節機構解明

    • Principal Investigator
      MATSUMURA Hiroyoshi
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Structural biology of carboxylases in C4 plantPrincipal Investigator

    • Principal Investigator
      KAI Yasushi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      工業物理化学
    • Research Institution
      Osaka University
  •  C4植物由来炭酸固定酵素PEPCのリン酸化による反応制御機構の解明Principal Investigator

    • Principal Investigator
      甲斐 泰
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Designing of inhibitors for prostaglandin D synthases based on crystallographic analyses

    • Principal Investigator
      URADE Yoshihiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      OSAKA BIOSCIENCE INSTITUTE
  •  Studies on Molecular Mechanisms for Carboxylation of RuBisCO toward High EfficiencyPrincipal Investigator

    • Principal Investigator
      KAI Yasushi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      工業物理化学
    • Research Institution
      Osaka University
  •  A CO_2 fixation enzme (PEP carboxylase) : Functional analysis by genetic engineering and X-ray chrystallography

    • Principal Investigator
      IZUI Katsura
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  X線構造解析の手法を用いた脳特異的カルシウム受容タンパク質S100の構造機能相関

    • Principal Investigator
      井上 豪
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  β-バレル構造を有する10種のブルー銅蛋白質のX線精密構造と電子移動挙動との相関Principal Investigator

    • Principal Investigator
      甲斐 泰
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  X線構造解析の手法を用いた脳特異的カルシウム受容タンパク質S100の構造と機能相関

    • Principal Investigator
      INOUE Tsuyoshi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Analysis of reaction in Organic CrystalsPrincipal Investigator

    • Principal Investigator
      KAI Yasushi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Design of Reactions in Crystals

    • Principal Investigator
      TODA Fumio
    • Project Period (FY)
      1994 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Ehime University
  •  生体系金属活性種の構造化学的研究Principal Investigator

    • Principal Investigator
      甲斐 泰
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Study on the structure-function correlation of CO_2-fixation enzymes toward the industrial applicationPrincipal Investigator

    • Principal Investigator
      KAI Yasushi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      工業物理化学
    • Research Institution
      Osaka University
  •  Study of Substrate-recognition Mechanism of Zn-metalloprotease

    • Principal Investigator
      HARADA Shigeharu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      University of Tokyo
      Osaka University
  •  生体系金属活性種の構造化学的研究Principal Investigator

    • Principal Investigator
      甲斐 泰
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  有機結晶工学

    • Principal Investigator
      笠井 暢民
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      結晶学
    • Research Institution
      Osaka University
  •  生体系金属活性種の構造化学的研究Principal Investigator

    • Principal Investigator
      甲斐 泰
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  分子性結晶の反応の解析と制御

    • Principal Investigator
      大橋 裕二
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Institute of Technology
  •  分子性結晶の反応の解析と制御

    • Principal Investigator
      大橋 裕二
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Institute of Technology
  •  分子性結晶の反応の解析と制御

    • Principal Investigator
      OHASHI Yuji
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Institute of Technology
  •  結晶場を利用した立体選択的反応の設計Principal Investigator

    • Principal Investigator
      甲斐 泰
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  結晶場を利用した立体選択的反応の設計Principal Investigator

    • Principal Investigator
      甲斐 泰
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  分子性結晶の反応の解析と制御

    • Principal Investigator
      大橋 裕二
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Ochanomizu University
  •  結晶場を利用した立体選択的反応の設計Principal Investigator

    • Principal Investigator
      甲斐 泰
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  結晶場を利用した反応の解析と制御

    • Principal Investigator
      大橋 裕二
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      結晶学
    • Research Institution
      Ochanomizu University
  •  Crystallization of Proteins for X-ray Analysis and the Accurate Intensity Data Measurement

    • Principal Investigator
      TANAKA Nobuo
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      結晶学
    • Research Institution
      Tokyo Institute of Technology
      Osaka University
  •  Design of chemical Reactions based on the Crystal Structures

    • Principal Investigator
      IWASAKI Fujiko
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      結晶学
    • Research Institution
      The University of Electro-Communications

All 2006 2005 2003

All Journal Article Book

  • [Book] 第5版 実験化学講座 5 化学実験のための基礎技術2006

    • Author(s)
      井上 豪, 松村浩由, 甲斐 泰
    • Total Pages
      15
    • Publisher
      丸善株式会社
    • Data Source
      KAKENHI-PROJECT-18054019
  • [Book] 第5版 実験化学講座 5 化学実験のための基礎技術2006

    • Author(s)
      井上 豪, 松村浩由, 甲斐 泰
    • Total Pages
      15
    • Publisher
      丸善株式会社
    • Data Source
      KAKENHI-PROJECT-18350086
  • [Book] 生体高分子化合物の結晶成長(第5版 実験化学講座5、化学実験のための基礎技術)2005

    • Author(s)
      井上豪, 松村浩由, 甲斐泰
    • Publisher
      丸善(株)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370045
  • [Book] 生体高分子化合物の結晶成長(第5版 実験科学講座5、化学実験のための基礎技術)2005

    • Author(s)
      井上豪, 松村浩由, 甲斐泰
    • Publisher
      丸善(株)
    • Data Source
      KAKENHI-PROJECT-16017260
  • [Journal Article] Crystallization and preliminary crystallographic analysis of orotidine 5'-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum2006

    • Author(s)
      S.R.Krungkrai, K.Tokuoka, Y.Kusakari, T.Inoue, H.Adachi, H.Matsumura, K.Takano, S.Murakami, Y.Mori, Y.Kai, J.Krungkrai, T.Horii
    • Journal Title

      Acta Crystallographica Section F 62巻6号

      Pages: 542-545

    • Data Source
      KAKENHI-PROJECT-18054019
  • [Journal Article] Crystallization and preliminary crystallographic analysis of orotidine 5'-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum2006

    • Author(s)
      S.R.Krungkrai, K.Tokuoka, Y.Kusakari, T.Inoue, H.Adachi, H.Matsumura, K.Takano, S.Murakami, Y.Mori, Y.Kai, J.Krungkrai, T.Horii
    • Journal Title

      Acta Crystallographica Section F 62巻6号

      Pages: 542-545

    • Data Source
      KAKENHI-PROJECT-18350086
  • [Journal Article] Crystal structure of intein homing endonuclease II encoded in the DNA polymerase gene from Hyperthermophilic Archaeon Thermococcus kodakaraensis strain KOD12006

    • Author(s)
      H.Matsumura, H.Takahashi, T.Inoue, T.Yamamoto, H.Hashimoto, M.Nishioka, S.Fujiwara, M.Takagi, T.Imanaka, Y.Kai
    • Journal Title

      Proteins : Structure Function, and Bioinformatics 63巻3号

      Pages: 711-715

    • Data Source
      KAKENHI-PROJECT-18054019
  • [Journal Article] Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilus2006

    • Author(s)
      T.Tsukazaki, H.Mori, S.Fukai, T.Numata, A.Perederina, H.Adachi, H.Matsumura, K.Takano, S.Murakami, T.Inoue, Y.Mori, T.Sasaki, Dmitry, G.Vassylyev, O.Nureki, K.Ito
    • Journal Title

      Acta Crystallographica Section F 62巻4号

      Pages: 376-380

    • Data Source
      KAKENHI-PROJECT-18350086
  • [Journal Article] Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilus2006

    • Author(s)
      T.Tsukazaki, H.Mori, S.Fukai, T.Numata, A.Perederina, H.Adachi, H.Matsumura, K.Takano, S.Murakami, T.Inoue, Y.Mori, T.Sasaki, Dmitry, G.Vassylyev, O.Nureki, K.Ito
    • Journal Title

      Acta Crystallographica Section F 62巻4号

      Pages: 376-380

    • Data Source
      KAKENHI-PROJECT-18054019
  • [Journal Article] Crystallization and preliminary X-ray analysis of the tRNA thiolation enzyme MnmA from Escherichia coli complexed with tRNA^<Glu>.2006

    • Author(s)
      T.Numata, Y.Ikeuchi, S.Fukai, H.Adachi, H.Matsumura, K.Takano, S.Murakami, T.Inoue, Y.Mori, T.Sasaki, T.Suzuki, O.Nureki
    • Journal Title

      Acta Crystallographica Section F 62巻4号

      Pages: 368-371

    • Data Source
      KAKENHI-PROJECT-18054019
  • [Journal Article] Crystallization and preliminary X-ray analysis of the tRNA thiolation enzyme MnmA from Escherichia coli complexed with tRNA^<Glu>.2006

    • Author(s)
      T.Numata, Y.Ikeuchi, S.Fukai, H.Adachi, H.Matsumura, K.Takano, S.Murakami, T.Inoue, Y.Mori, T.Sasaki, T.Suzuki, O.Nureki
    • Journal Title

      Acta Crystallographica Section F 62巻4号

      Pages: 368-371

    • Data Source
      KAKENHI-PROJECT-18350086
  • [Journal Article] Crystal structure of intein homing endonuclease II encoded in the DNA polymerase gene from Hyperthermophilic Archaeon Thermococcus kodakaraensis strain KOD12006

    • Author(s)
      H.Matsumura, H.Takahashi, T.Inoue, T.Yamamoto, H.Hashimoto, M.Nishioka, S.Fujiwara, M.Takagi, T.Imanaka, Y.Kai
    • Journal Title

      Proteins : Structure Function, and Bioinformatics 63巻3号

      Pages: 711-715

    • Data Source
      KAKENHI-PROJECT-18350086
  • [Journal Article] Phosphoenolpyruvate carboxylase : Three-Dimensional structure and molecular mechanisms2003

    • Author(s)
      Yasushi, Kai, et al.
    • Journal Title

      Arch.Biochem.Biophys 414

      Pages: 170-179

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370045
  • [Journal Article] Phosphoenolpyruvate carboxylase : Three-dimensional structure and molecular mechanisms2003

    • Author(s)
      Yasushi Kai, et al.
    • Journal Title

      Arch.Biochem.Biophys. 414

      Pages: 170-179

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370045
  • [Journal Article] Phosphoenolpyruvate carboxylase: Three-dimensional structure and molecular mechanisms2003

    • Author(s)
      Yasushi Kai, et al.
    • Journal Title

      Arch.Biochem.Biophys. 414

      Pages: 170-179

    • Data Source
      KAKENHI-PROJECT-15370045
  • 1.  INOUE Tsuyoshi (20263204)
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  • 2.  OHASHI Yuji (40016118)
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  • 19.  OKAMOTO Yoshio (60029501)
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