YAMAMOTO Kenji 山本健二

… Alternative Names

山本建二ヤマモトケンジ

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Researcher Number	40091326
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012: 九州大学, 薬学研究院, 特命教授 2011 – 2012: 九州大学, 大学院・薬学研究院, 特命教授 2008 – 2010: Kyushu University, 大学院・薬学研究院, 特任教授 2009: Kyushu University, 薬学研究院, 特任教授 2008: 九州大学, 大学院・薬学研究院, 教授 … More 2007: Kyushu University, 大学院・歯学研究院, 助教 2007: Nagasaki University, Department of Pharmacology Graduate School of Dental Science, Professor 2006: 九州大学, 歯学研究院, 教授 2005: 九州大学, 大学院歯学研究院, 教授 2000 – 2005: KYUSHU UNIVERSITY, GRADUATE SCHOOL OF DENTAL SCIENCE, PROFESSOR, 大学院・歯学研究院, 教授 1989 – 1999: 九州大学, 歯学部, 教授 1987 – 1988: 長崎大学, 歯学部, 助教授 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry / Biological Sciences Except Principal Investigator Functional basic dentistry / Functional basic dentistry / Conservative dentistry
Keywords	Principal Investigator Porphyromonas gingivalis / Arg-gingipain / カテプシンE / 歯周病 / Lys-gingipain / アスパラギン酸プロテアーゼ / ジンジバリス菌 / プロテアーゼ / システインプロテアーゼ / カテプシンD … More / プロセシング / カテプシン / ジンジパイン / 歯学 / 生合成 / 歯周病治療薬 / 病原性因子 / periodontal disease / Periodontal disease / 歯肉溝滲出液 / 歯周疾患 / 病原性プロテアーゼ / 薬理学 / 免疫学 / 癌 / 感染症 / エンドソーム・リソソーム系 / 蛋白質分解 / 生体防御 / 歯周病原性プロテアーゼ / 胸腺細胞 / ミクログリア / 細胞内アスパラギン酸プロテアーゼ / virulence factors / cathepsins / proteinases / 歯周病原菌 / cysteine proteinases / CATHEPSIN L / CATHEPSIN B / プロテア-ゼ / 歯周病原性菌 / 臨床評価法 / 歯周組織の破壊 / タンパク分解酵素 / 病原性細菌 / オートファジー / ノックアウトマウス / リソソーム系 / エンドソーム / ノックアウト / グラム陰性嫌気性細菌 / CHO細胞 / フレンド細胞 / 細胞内輸送 / Proteases / Pharmacology / Immunology / Dentistry / Tumor / Infectious disease / 免疫応答 / Drugs for periodontal disease / Specific inhibitor / Gingipains / Protease / Virulence factor / 特異的阻害剤 / host defense mechanisms / aspartic proteinases / gingipains / グラム陰性嫌気細菌 / アミノ酸・ヘム獲得 / 生存戦略 / プロテアーゼ機能 / 宿主細胞傷害活性 / グラム陰性嫌気性細胞 / 生体防御系 / novel inhibitors / porphyromonas gingivalis / gram-negative anaerobic bacterium / pathogen / periodontitis / 歯周病ワクチン / プロテアーゼインヒビター / インヒビター / Agr-gingipain / 歯周菌 / 放線菌 / 新規阻害物質 / crysteine proteinase / oral anaerobic bacterium / 病原菌プロテアーゼ / 病原性発現機序 / Porphyromonase gingivalis / oral bacterium / drug design / clinical parameter / 臨床評価法の確立 / 治療薬の開発 / primary structures / cloning / a virulence factor / periodontal pathogen / 機能と病態 / 蛋白質一次構造 / 遺伝子のクローニング / 病原性システインプロテアーゼ / Argingipain / 病原因子 / CATHEPSIN D / LYSOSOMAL MEMBRANE PROTEIN / BONE RESORPTION / OSTEOCLAST / リソゾ-ム膜タンバン質 / 免疫組織学 / 骨吸収 / 破骨細胞 / リソソーム膜 / GINGIVAL CREVICULAR FLUID / MEDULLASIN / CATHEPSIN G / CATHEPSIN H / GINGIVITIS / PERIODONTITIS / カテプシンG / 顆粒球セリンプロテア-ゼ / 歯周組織破壊 / Proteinases / Periodontal tissue / 臨床パラメ-タ / 実験的歯肉炎 / 歯周組織の破壊機構 / 歯周組識の破壊 / 抗菌作用 / ラクトフェリン / 唾液 / 薬学 / 細菌 / 酵素 / 蛋白質分子進化技術 / 早期診断キット / 分子標的治療薬 / 発現制御 / トランスレーショナルリサーチ / 蛋白質 / リソーム系 / バッテン病 / 神経系 / 品質管理 / 神経変性疾患 / 蛋白質分解酵素 / エンドソーム・リソソーム / オートオファジー / タンパク質分解 / マクロファージ / Prophyromonas gingivalis / 酵素欠損変異体 / 蛋白分解システム / 選別輸送機構 / チャイニーズハムスター卵巣細胞 / マウス白血病フレンド細胞 / 活性化機構 / カプテシンD … More Except Principal Investigator カテプシンE / プロテアーゼ / カテプシンD / LPS / Bcl-2 / 歯周病 / ミクログリア / Porphyromonas gingivalis / ovalbumin / microglia / cathepsin E / PC12細胞 / 老化 / ジンジパイン / 動脈硬化症 / エンドソーム / 初代培養ミクログリア / 酵素活性 / 免疫組織化学 / アスパラギン酸プロテアーゼ / メダラシン / カテプシンH / カテプシンB / Cathepsin E / Cathepsin D / Cathepsin H / Cathepsin B / Lysosomal proteinases / 抗炎症剤 / リソゾーム酵素 / カテプシンL / リソゾーム性酵素 / protease / gingiva / skin / deficient mice / epithelial cells / lysosomes / endosomes / cathepsin / ノックアウトマウス / リソソーム / カテプシン / 上皮細胞 / molecular complex / gingipains / atherosclerosis / Protease / biological response / periodontal disease / マクロファージ / ジンジバリス菌 / 複合体 / 生体応答 / cathepsin D-deficient mice / invaliant chain / antigenic peptide / antigen presentation / cathepsin D / インターフェロン-γ / インターロイキン-2 / pepstatin A / カテプシン阻害剤 / カテプシンD欠損マウス / インバリアント鎖 / 抗原ペプチド / 抗原提示 / カテプシンンD / APOPTOSIS / BCL-2 / CASPASE-3 / PC12 CELL / PEPSTATIN A / LIPOPOLYSACCHARIDE / INTERFERON-gamma / MICROGLIA / CATHEPSIN E / ルミノール反応 / イムノブロット / ネクローシス / INF-γ / アポトーシス / カスパーゼ3 / ペプスタチンA / IFN-γ / caspase / PC12 cells / aging / neuronal death / intracellular aspartic proteinase / 分化誘導 / 遺伝子導入 / 神経細胞 / 細胞死モデル / PC19細胞 / カスパーゼ / 神経細胞死 / 細胞内アスパラギン酸プロテアーゼ / pyramidal cell / glutamatr / GABA / field potential / hipopcampus / long-term potentiation / powder food / pelet food / 膜抵抗 / シナプス長期増強 / 膜電位 / 痴呆症 / ルシファーイエロ- / 咀嚼運動 / 海馬切片 / 粉末飼料 / 固形飼料 / PERIODONTAL DISEASES / PROTEINASE / PORPHYROMONAS GINGIVALIS / ポルフィロモナスジンジバリス / ポルフィロモナス・ジンジバリス / PHAGOCYTOSIS / LYSOSOME / AGING / TRIGEMINAL GANGLION / CATHEPSINS / ラット / 免疫電顕 / 免疫組織 / カテプシン群 / リソソーム系蛋白分解機構 / 三叉神経節神経細胞 / ジンジバイン / P.gingvalis / P. gingivalis / インスリン抵抗性 / 生活習慣病 / 動脈硬化 / 糖尿病 / 細菌感染 / 糖鎖 / プロセッシング / 生合成 / DNA損傷 / 逆行性変性 / 顔面神経核 / ライソゾーム膜糖蛋白質 / 蛋白質分解酵素 / 破骨細胞 / 骨芽細胞 / 骨改造現象 / 咬筋運動ニューロン / 分解調節 / basic FGF / P.gingivalis / 歯肉溝滲出液 / 好中球 / 歯周病原性菌 / 歯周組織破壊 / 歯周疾患 / プロテア-ゼ / 細胞内プロテア-ゼ / リソゾ-ム性酵素 Less

Relationship between periodontal disease and systemic diseases: molecular mechanisms and novel therapy discoveryPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
蛋白質高速分子進化技術による歯周病の分子標的治療薬及び早期診断キットの開発Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Protease-mediated regulation of host immune system and application as therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Experimental analysis of the correlation between periodontal disease and insulin resistance
- Principal Investigator
  
  TSUKUBA Tomoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Function of endo-lysosomal proteinases in epithelial cells
- Principal Investigator
  
  TSUKUBA Takayuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
  Kyushu University
生体防御系におけるプロテアーゼの機能解析Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Examination of biological response to Porphyromonas gingivalis infection.
- Principal Investigator
  
  TSUKUBA Tomoko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
Molecular basis of host immune responses to periodontal diseasePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
歯周病における免疫制御系プロテアーゼの機能解析Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
ESTABLISHMENT OF A CLINICAL TREATMENT SYSTEM FOR PERIODONTAL DISEASEPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
神経系におけるオートファジー・リソソームシステムPrincipal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
MOLECULAR BASIS OF PROTEINASE FUNCTION IN PROGRESSION OF PERIODONTAL DISEASESPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
Involvement of cathepsin E in exogenous antigen processing in primary cultured microglia
- Principal Investigator
  
  NAKANISHI Hiroshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割Principal Investigator
- Principal Investigator
  
  山本建二
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
カテプシンEの生合成と細胞内輸送および局在化機構の解析Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
歯周病原菌における蛋白分解システムとその異常の分子レベル解析Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
DESIGN AND DEVELOPMENT OF THERAPEUTIC AGENTS OF ADULT PERIODONTITIS THAT INHIBIT ARG-GINGIPAIN PRODUCED BY PORPHYROMONAS GINGIVALISPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
Effect of overexpression of cathepsin E and Bcl-2 on neuronal death
- Principal Investigator
  
  HORI Nobuaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
EXPRESSION AND FUNCTION OF CATHEPSIN E IN ACTIVATED MICROGLIA FOLLOWING FACIAL NERVE INJURY
- Principal Investigator
  
  NAKANISHI Hiroshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
細胞内アスパラギン酸プロテアーゼの機能構造形成と細胞機能制御Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
顔面神経切断に伴って増殖する反応性ミクログリアにおけるカテプシンEの性状解析
- Principal Investigator
  
  中西博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
ROLES OF PATHOGENIC PROTEINASES IN PERIODONTAL DISEASEPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
骨吸収開始時期における骨細胞および骨芽細胞由来の調節因子の解析
- Principal Investigator
  
  AKAMINE Akifumi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kyushu University
DNA断片化ならびに細胞内プロテアーゼの動態を指標として逆行性神経変性の検討
- Principal Investigator
  
  中西博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
GENETIC AND BIOCHEMICAL STUDY ABOUT FUNCTION AND SECRETION MECHANISM OF EXTRACELLULAR PROTEINASES OF PERIODONTOPATHOGENIC MICROORGANISMS
- Principal Investigator
  
  NAKAYAMA Koji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
Effects of mechanical loads of feeding on the physiological development of a central nervous system.
- Principal Investigator
  
  HORI Nobuaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
細胞内アスパラギン酸プロテアーゼの選別と輸送機構Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
アスパラギン酸プロテアーゼによる生理活性ペプチドの分解を介した三叉神経機能の調節
- Principal Investigator
  
  中西博
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Structures and Functions of Periodontopathogenic ProteinasesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
DEVELOPMENT OF A NEW CLINICAL PARAMETER FOR ASSESSMENT OF PROGRESSIVE PERIODONTAL DIDEASE AND ITS THERAPEUTIC AND PREVENTIVE DRUGSPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUShU UNIVERSITY
歯周病原性プロテアーゼの機能と病態
- Principal Investigator
  
  KAMATA Osamu
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
PHYSIOLOGICAL AND PATHOLOGICAL STUDIES OF PROTEINASES IN THE RAT TRIGEMINAL GANGLION CELLS
- Principal Investigator
  
  NAKANISHI Hiroshi Ph.D.
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
ROLES OF PROTEOLYTIC ENZYMES AND LYSOSOMAL MEMBRANE PROTEINS IN BONE RESORBING PROCESSPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
THE DEVELOPMENT OF A NEW CLINICAL PARAMETER FOR DIAGNOSIS OF PERIODONTAL DISEASES AND THE NEW DRUG DESIGNPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
硬組織に由来する細胞の機能発現とリソゾ-ム性酵素の役割に関する実験薬理学的研究
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
The Pole of Proteinases in Periodontal Tissue BreakdownPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
唾液内ラクトフェリンの抗菌機序と歯科疾患適用への基礎的研究Principal Investigator
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Roles of lysosomal proteinases in the patho-physiological changes of hard tissues.
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University

All 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001

All Journal Article Presentation Book Patent

[Book] 現代歯科薬理学(第4版)2005
- Author(s)
  山本健二
- Total Pages
  548
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-16659514
[Book] 現代歯科薬理学(第4版)2005
- Author(s)
  山本健二
- Total Pages
  548
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-15209062
[Book] 実験医学 22, 213-2192004
- Author(s)
  山本健二, 岩田淳一
- Total Pages
  219
- Data Source
  KAKENHI-PROJECT-15209062
[Book] 実験医学 222004
- Author(s)
  山本健二
- Publisher
  洋土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Book] 実験医学2004
- Author(s)
  山本健二, 岩田淳一
- Total Pages
  219
- Data Source
  KAKENHI-PROJECT-16659514
[Book] 実験医学 22,213-2192004
- Author(s)
  山本健二, 岩田淳一
- Publisher
  (印刷中)
- Data Source
  KAKENHI-PROJECT-12146203
[Book] 実験医学 22, 213-2192004
- Author(s)
  山本健二, 岩田淳一
- Total Pages
  219
- Data Source
  KAKENHI-PROJECT-13357016
[Book] 実験医学第22巻2004
- Author(s)
  山本健二
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Book] 日本薬理学会誌 1222003
- Author(s)
  山本健二
- Publisher
  日本薬理学会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Book] 臨床検査 472003
- Author(s)
  山本健二
- Publisher
  医学書院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Book] 臨床検査第47巻2003
- Author(s)
  山本健二
- Publisher
  医学事院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Book] 化学と生物第40巻2002
- Author(s)
  山本健二
- Publisher
  学会出版センター
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Book] タンパク質分解の不思議2001
- Author(s)
  山本健二
- Publisher
  クバクロ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Book] 蛋白質核酸酵素第46巻2001
- Author(s)
  山本健二
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Book] 医学のあゆみ第198巻2001
- Author(s)
  山本健二
- Publisher
  医歯薬出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Effect of a Japanese energy healing method known as Johrei on viability and proliferation of cultured cancer cells in vitro2012
- Author(s)
  Abe K, Ichinomiya R, Kanai T, Yamamoto K
- Journal Title
  
  J Alternat. Comlement. Med
  
  Volume: 18(3) Pages: 221-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Emerging roles of cathepsin E in host defense mechanisms2012
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1824 Pages: 105-112
- NAID
  120005324431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Emerging roles of cathepsin E in host defense mechanisms2012
- Author(s)
  Yamamoto, K., et al
- Journal Title
  
  Biochim.Biophys.Acta.
  
  Volume: 1824 Issue: 1 Pages: 105-112
- DOI
  10.1016/j.bbapap.2011.05.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
[Journal Article] Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene2012
- Author(s)
  Okamoto K
- Journal Title
  
  J.Biochem.
  
  Volume: 151 Issue: 3 Pages: 263-272
- DOI
  10.1093/jb/mvr135
- NAID
  10031166065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592369, KAKENHI-PROJECT-22592086, KAKENHI-PROJECT-24659840, KAKENHI-PROJECT-22390350
[Journal Article] Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene2012
- Author(s)
  Okamoto K, Okamoto Y, Kawakubo T, Iwata J, Yasuda Y, Tsukuba T, Yamamoto K
- Journal Title
  
  J Biochem.
  
  Volume: 151 Pages: 263-272
- NAID
  10031166065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene2012
- Author(s)
  Okamoto K, Okamoto Y, Kawakubo T, Iwata J, Yasuda Y, Tsukuba T, Yamamoto K
- Journal Title
  
  J Biochem
  
  Volume: 151(3) Pages: 263-272
- NAID
  10031166065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E is critical for the proper trafficking of both intracellular membrane and cell surface proteins2012
- Author(s)
  Tsukuba T, Okamoto K, Yamamoto K
- Journal Title
  
  J. Oral Biosci
  
  Volume: 54 (1) Pages: 48-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E is critical for the proper trafficking of both intracellular membrane and cell surface proteins2012
- Author(s)
  Tsukuba T, Okamoto K, Yamamoto K.
- Journal Title
  
  J. Oral Biosci.
  
  Volume: 54 Pages: 48-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E is critical for the proper trafficking of both intracellular membrane and cell surface proteins2012
- Author(s)
  Tsukuba T, Okamoto K, Yamamoto K
- Journal Title
  
  J.Oral Biosci.
  
  Volume: 54 Pages: 48-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E as a potent anticancer protease.2011
- Author(s)
  Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K.
- Journal Title
  
  J.Oral Biosci.
  
  Volume: 53(印刷中)
- NAID
  10028222723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Emerging roles of cathepsin E in host defense mechanisms2011
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T.
- Journal Title
  
  Biochim.Biophys.Acta
  
  Volume: (印刷中)
- NAID
  120005324431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Effect of a Japanese energy healing method known as Johrei on viability and proliferation of cultured cancer cells in vitro2011
- Author(s)
  Abe K, Ichinomiya R, Kanai T, Yamamoto K
- Journal Title
  
  J Alternat.Comlement.Med.
  
  Volume: 18 Issue: 3 Pages: 221-228
- DOI
  10.1089/acm.2011.0467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] The role of cathepsin E in terminal differentiation of keratinocytes2011
- Author(s)
  Kawakubo T, Yasukochi A, Okamoto K, Okamoto Y, Nakamura S, Yamamoto K
- Journal Title
  
  Biol. Chem
  
  Volume: 392 Pages: 571-583
- NAID
  120005007885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E as a potent anticancer protease2011
- Author(s)
  Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K
- Journal Title
  
  J. Oral Biosci
  
  Volume: 53 (2) Pages: 126-136
- NAID
  10028222723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E as a potent anticancer protease2011
- Author(s)
  Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K
- Journal Title
  
  J.Oral Biosci.
  
  Volume: 53 Pages: 126-136
- NAID
  10028222723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Peptide aptamer-based ELISA-like system for detection of cathepsin E in tissues and plasma2011
- Author(s)
  Kitamura K, Biyani M, Futakami M, Ueno-Tsuji S, Suzuki M, Kawakubo T, Yamamoto K, Nishigaki K
- Journal Title
  
  J.Mol.Biomark.Diagn.
  
  Volume: 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] The role of cathepsin E in terminal differentiation of keratinocytes2011
- Author(s)
  Kawakubo T
- Journal Title
  
  Biol.Chem.
  
  Volume: 392 Issue: 6 Pages: 571-585
- DOI
  10.1515/bc.2011.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592369, KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
[Journal Article] Peptide aptamer-based ELISA-like system for detection of cathepsin E in tissues and plasma2011
- Author(s)
  Kitamura, K., et al
- Journal Title
  
  Mol.Biomark.Diagn.
  
  Volume: 2 Issue: 01 Pages: 104-104
- DOI
  10.4172/2155-9929.1000104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
[Journal Article] In vitro selection of cathepsin E-activity-enhancing peptide aptamers at neutral pH2011
- Author(s)
  Biyani M, Futakami M, Kitamura K, Kawakubo T, Suzuki M, Yamamoto K, Nishigaki K
- Journal Title
  
  Int. J. Pep
  
  Volume: 2011 Pages: 1-8
- DOI
  10.1155/2011/834525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone in vasion by oral squamous cell carcinoma cells2011
- Author(s)
  Shin M, et al
- Journal Title
  
  Carcinogenesis
  
  Volume: 32 Issue: 11 Pages: 1634-1640
- DOI
  10.1093/carcin/bgr198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592247, KAKENHI-PROJECT-22791795, KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis.2010
- Author(s)
  Yasukochi A, Kawakubo T, Nakamura S, Yamamoto K.
- Journal Title
  
  Biol Chem (in press)
- NAID
  120006900038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis2010
- Author(s)
  Yasukouchi A, Kawakubo T, Nakamura S, Yamamoto K
- Journal Title
  
  Biol. Chem
  
  Volume: 391 Pages: 947-958
- NAID
  120006900038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostatecancer cells showing resistance to TRAIL-mediated apoptosis2010
- Author(s)
  Yasukochi A, Kawakubo T, Nakamura S, Yamamoto K
- Journal Title
  
  Biol.Chem.
  
  Volume: 391 Pages: 947-958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] 大学改革後の歩みと国際競争力2010
- Author(s)
  山本健二
- Journal Title
  
  生化学
  
  Volume: 81 Pages: 363-363
- NAID
  10026425747
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Impaired chemotaxis and cell adhesion due to decrease in wide range of cell surface receptors in cathepsin E-deficient macrophages.2009
- Author(s)
  Tsukuba T, Yanagawa M, Okamoto K, Okamoto Y, Yasuda Y, Nakayama KI, Kadowaki T, Yamamoto K.
- Journal Title
  
  J. Biochem. 145(5)
  
  Pages: 565-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Development of systemin in vitro evolution and its application to generation of peptide aptamer-based inhibitors of cathepsin E.2009
- Author(s)
  Kitamura K, Yoshida C, Kinoshita Y, Kadowaki T, Takahashi Y, Tayama T, Kawakubo T, Naimuddin M, Salimulla M, Nemoto N, Hanada K, Husimi Y, Yamamoto K, Nishigaki K.
- Journal Title
  
  J. Mol. Biol. 387
  
  Pages: 1186-1198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Gene expression of profiling of mammary glands of cathepsin E-deficient mice compared with wild-type littermates.2008
- Author(s)
  Kawakubo T., Yasukochi A., Tsukuba T., Kadowaki T., Yamamoto K.
- Journal Title
  
  Biochimie 90
  
  Pages: 396-404
- NAID
  120006900027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] An immunohistochemical study on a unique colocalization relationship between substance P and GABA in the central nucleus of amygdala.2008
- Author(s)
  Shigematsu, N., Yamamoto, K., Higuchi, S., Fukuda, T.
- Journal Title
  
  Brain Res. 1198
  
  Pages: 55-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mice2008
- Author(s)
  Shigematsu N, Fukuda T, Yamamoto T, Nishioku T, Yamaguchi T, Himeno M, Nakayama. KI, Tsukuba T, Kadowaki T, Okamoto K, Higuchi S, Yamamoto K.
- Journal Title
  
  J Neurochem. 105
  
  Pages: 1394-1404
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Determination of active site of Lysine-specific cysteine proteinase (Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system2008
- Author(s)
  Ishida Y, Hu JP, Sakai E, Kadowaki T, Yamamoto K, Tsukuba T, Nakayama K, Okamoto K
- Journal Title
  
  Arch. Oral Biol 53
  
  Pages: 538-544
- NAID
  120006984583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Determination of active site of lysine-specific cysteine proteinase(Lys-gingipain)by use of a Porphyromonas gingivalis plasmid system2008
- Author(s)
  Ishida Y, Hu J, Sakai E, Kadowaki T, Yamamoto K, Tsukuba T, Kato Y, Nakayama K, Okamoto K.
- Journal Title
  
  Arch Oral Biol. 53
  
  Pages: 538-544
- NAID
  120006984583
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mouse2008
- Author(s)
  Shigematsu N., Fukuda T., Yamamoto T., Nishioku T., Yamaguchi T., Himeno M., Nakayama K.I., Tsukuba T., Kadowaki T., Okamoto K., Higuchi S., Yamamoto K.
- Journal Title
  
  J. Neurochem. 105
  
  Pages: 1394-1404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Determination of active site of lysine-specific cysteine proteinase(Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system2008
- Author(s)
  Y, Hu, J, Sakai, E, Kadowaki, T, Yamamoto, K, Tsukuba, T, Kato, Y, Nakayama, K, Okamoto, K
- Journal Title
  
  Arch Oral Biol (in press)
- NAID
  120006984583
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mice2008
- Author(s)
  Shigematsu, N, Fukuda, T, Yamamoto, T, Nishioku, T, Yamaguchi, T, Himeno, M, Nakayama, KI, Tsukuba, T, Kadowaki, T, Okamoto, K, Higuchi, S, Yamamoto, K
- Journal Title
  
  J Neurochem (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mouse2008
- Author(s)
  Shigematsu N, Fukuda T, Yamamoto T, Nishioku T, Yamaguchi T, Himeno M, Nakayama KI, Tsukuba T, Kadowaki T, Okamoto K, Higuchi S, Yamamoto K.
- Journal Title
  
  J. Neurochem 105
  
  Pages: 1394-1404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell Surface2008
- Author(s)
  Kawakubo T, Okamoto K, Iwata J, Shin M, Okamoto Y, Yasukochi A, Nakayama KI, Kadowaki T, Tsukuba T, Yamamoto K.
- Journal Title
  
  Cancer Res 67
  
  Pages: 10869-10878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Determination of active site of Lysine-specific cysteine proteinase (Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system.2008
- Author(s)
  Ishida Y., Hu J.P., Sakai E., Kadowaki T., Yamamoto K., Tsukuba T., Nakayama K., Okamoto K.
- Journal Title
  
  Arch. Oral Biol. 53(6)
  
  Pages: 538-544
- NAID
  120006984583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Gene expression profiling of mammary elands of cathepsin E-deficient mice compared with wild-type littermates2008
- Author(s)
  Kawakubo, T, Yasukochi, A, Tsukuba, T, Kadowaki, T, Yamamoto, K
- Journal Title
  
  Biochimie 90
  
  Pages: 396-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erthrocytes, and inhibition of hemaggelutination by an interdomain regional peptide.2007
- Author(s)
  Sakai, E., Naito, M., Sato, K., Hotokezaka, H., Kadowaki, T., Kamaguch, A., Yamamoto, K., Okamoto, K., Nakayama, K.
- Journal Title
  
  J. Bacteriol. 189
  
  Pages: 3977-3986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an interdomain regional peptide2007
- Author(s)
  Sakai, E, Naito, M, Sato, K, Hotokezaka, H, Kadowaki, T, Kamaguchi, A, Yamamoto, K, Okamoto, K, Nakayama, K
- Journal Title
  
  J Bacteriol 189
  
  Pages: 3977-3986
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Role for gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelilal cells.2007
- Author(s)
  Yamatake, K., Maeda, M., Kadowaki, T., Takii, R., Tsukuba, T., Ueno, T., Kominami, E., Yokota, S., Yamamoto, K.
- Journal Title
  
  Infect. Immun. 75
  
  Pages: 2090-2100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell2007
- Author(s)
  Kawakubo T., Okamoto K., Iwata J., Shin M., Okamoto Y., Yasukochi A., Nakayama K.I., Kadowaki T., Tsukuba T., Yamamoto K.
- Journal Title
  
  Surface. Cancer Res. 67
  
  Pages: 10869-10878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007
- Author(s)
  Kakehashi H, Nishioku T, Tsukuba T, Kadowaki T, Nakamura S, Yamamoto K.
- Journal Title
  
  J Immunol. 179
  
  Pages: 5728-5737
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Gene expression profiling of mammary glands of cathepsin E-deficient mice compared with wild-type littermates2007
- Author(s)
  Kawakubo T, Yasukochi A, Tsukuba T, Kadowaki T, Yamamoto K.
- Journal Title
  
  Biochimie. 90
  
  Pages: 396-404
- NAID
  120006900027
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Selection-by-function : efficient enrichment of cathepsin E inhibitors from a DNA library2007
- Author(s)
  Naimuddin, M, Kitamura, K, Kinoshita, Y, Honda-Takahashi, Y, Murakami, M, Ito, M, Yamamoto, K, Hanada, K, Husimi, Y, Nishigaki, K
- Journal Title
  
  J Mol Recognit 20
  
  Pages: 58-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases2007
- Author(s)
  Kanaji, S, Tanaka, Y, Sakata, Y, Takeshita, K, Arima, K, Ohta, S, Hansell, EJ, Caffrey, C, Mottram, JC, Lowther, J, Donnelly, S, Stack, C, Kadowaki, T, Yamamoto, K, McKerrow, JH, Dalton, JP, Coombs, GH, Izuhara, K
- Journal Title
  
  FEBS Lett 581
  
  Pages: 4260-4264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] The role for Gingipains in Porphyromonas gingivalis traffic to phagol ysosomes and survival in human aortic endothelial cells2007
- Author(s)
  Yamatake K., Maeda M., Kadowaki T., Takii, R., Tsukuba T., Ueno T., Kominami, E., Yokota S., Yamamoto K.
- Journal Title
  
  Infect.Immun 75
  
  Pages: 2090-2100
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingivalis-infected cells2007
- Author(s)
  Kadowaki, T, Takii, R, Yamatake, K, Kawakubo, T, Tsukuba, T, Yamamoto, K
- Journal Title
  
  Front Biosci 12
  
  Pages: 4800-48009
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases.2007
- Author(s)
  Kanaji, S., Tanaka, Y., Sakata, Y., Takeshita, K., Arima, K., Ohta, S., Hansell, E.J., Caffrey, C., Mottram, J.C., Lowther, J., Donnelly, S., Stack, C., Kadowaki, T., Yamamoto, K., McKerrow, J.H., Dalton, J.P., Coombs, G.H., Izuhara, K.
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 4260-4264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Selection-by-function:efficient enrichment of cathepsin E inhibitors from a DNA library2007
- Author(s)
  Naimuddin M, Kitamura K, Kinoshita Y, Honda-Takahashi Y, Murakami M, Ito M, Yamamoto K, Hanada K, Husimi Y, Nishigaki K.
- Journal Title
  
  J Mol Recognit. 20
  
  Pages: 58-68
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases2007
- Author(s)
  Kanaji S, Tanaka Y, Sakata Y, Takeshita K, Arima K, Ohta S, Hansell EJ, Caffrey C, Mottram JC, Lowther J, Donnelly S, Stack C, Kadowaki T, Yamamoto K, McKerrow JH, Dalton JP, Coombs GH, Izuhara K.
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 4260-4264
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses2007
- Author(s)
  Shin, M, Kadowaki, T, Iwata, J, Kawakubo, T, Yamaguchi, N, Takii, R, Tsukuba, T, Yamamoto, K
- Journal Title
  
  Biol Chem 388
  
  Pages: 1173-1181
- NAID
  120006900037
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Selection-by-function: effifient enrichment of cathepsin E inhibitors from a DNA library.2007
- Author(s)
  Naimuddin, M., Kitamura, K., Kinoshita, Y., Honda-Takehashi, Y., Murakami, M., Ito, M., Yamamoto, K., Hanada, K., Husimi, Y., Nishigaki, K.
- Journal Title
  
  J. Mol. Recognit. 20
  
  Pages: 58-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] The Role for Gingipains in Porphyromonas gingivalis Traffic to Phagolysosomes and Survival in Human Aortic Endothelial Cells2007
- Author(s)
  Yamatake K, Maeda M, Kadowaki T, Takii R, Tsukuba T, Ueno T, Kominami E, Yokota S, Yamamoto K
- Journal Title
  
  Infect. Immun 75
  
  Pages: 2090-2100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E.2007
- Author(s)
  Kakehashi H., Nishioku T., Tsukuba T., Kadowaki T., Nakamura S., Yamamoto K.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 5728-5737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007
- Author(s)
  Kakehashi H, Nishioku T, Tsukuba T, Kadowaki T, Nakamura S, Yamamoto K.
- Journal Title
  
  J. Immunol 179
  
  Pages: 5728-5737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an inter-domain regional peptide2007
- Author(s)
  Sakai E, Naito M, Sato K, Hotokezaka H, Kadowaki T, Kamaguchi A, Yamamoto K, Okamoto K, Nakayama K.
- Journal Title
  
  J Bacteriol 189
  
  Pages: 3977-3986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder in macrophages showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH. *Both authors contributed equally to this work2007
- Author(s)
  Yanagawa, M*, Tsukuba, T*, Nishioku, T, Okamoto, Y, Okamoto, K, Takii, R, Terada, Y, Nakayama, KI, Kadowaki, T, Yamamoto, K
- Journal Title
  
  J. Biol Chem 282
  
  Pages: 1851-1862
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingivalis-infected cells2007
- Author(s)
  Kadowaki T, Takii R, Yamatake K, Kawakubo T, Tsukuba T, Yamamoto K
- Journal Title
  
  Front Biosci 12
  
  Pages: 4800-4809
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] The role for Gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelial cells2007
- Author(s)
  Yamatake, K, Maeda, M, Kadowaki, T, Takii, R, Tsukuba, T, Ueno, T, Kominami, E, Yokota, S, Yamamoto, K
- Journal Title
  
  Infect Immun 75
  
  Pages: 2090-2100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007
- Author(s)
  Kakehashi, H, Nishioku, T, Tsukuba, T, Kadowaki, T, Nakamura, S, Yamamoto, K
- Journal Title
  
  J Immunol 179
  
  Pages: 5728-5737
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingicalis-infected cells.2007
- Author(s)
  Kadowaki, T., Takii, R., Yamatake, K., Kawakubo, T., Tsukuba, T., Yamamoto, K.
- Journal Title
  
  Frontiers in Biosci. 12
  
  Pages: 4800-4809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface2007
- Author(s)
  Kawakubo T, Okamoto K, Iwata J, Shin M, Okamoto Y, Yasukochi A, Nakayama KI, Kadowaki T, Tsukuba T, Yamamoto K.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 10869-10878
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface2007
- Author(s)
  Kawakubo, T, Okamoto, K, Iwata, J, Shin, M, Okamoto, Y, Yasukochi, A, Nakayama, KI, Kadowaki, T, Tsukuba, T, Yamamoto, K
- Journal Title
  
  Cancer Res 67
  
  Pages: 10869-10878
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses2007
- Author(s)
  Shin M, Kadowaki T, Iwata J, Kawakubo T, Yamaguchi N, Takii R, Tsukuba T, Yamamoto K.
- Journal Title
  
  Biol Chem. 388
  
  Pages: 1173-1181
- NAID
  120006900037
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder 5 showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in macrophages.2007
- Author(s)
  Yanagawa, M., Tsukuba, T., Nishioku, T., Okamoto, Y., Okamoto, K., Takii, R., Terada, Y., Nakayama, K.T., Kadowaki, T., Yamamoto, K
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 1851-1862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis,identification of its target protein on erythrocytes,and inhibition of hemagglutination by an interdomain regional peptide2007
- Author(s)
  Sakai E, Naito M, Sato K, Hotokezaka H, Kadowaki T, Kamaguchi A, Yamamoto K, Okamoto K, Nakayama K.
- Journal Title
  
  J Bacteriol. 189
  
  Pages: 3977-3986
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses.2007
- Author(s)
  Shin, M., Kadowaki, T., Iwata, J., Kawakubo, T., Yamaguchi, N., Takii, R., Tsukuba, T., Yamamoto, K.
- Journal Title
  
  Biol. Chem. 388
  
  Pages: 1173-1181
- NAID
  120006900037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure2006
- Author(s)
  Hashimoto, M, Kadowaki, T, Tsukuba, T, Yamamoto, K
- Journal Title
  
  J. Biochein 140
  
  Pages: 713-723
- NAID
  10018841154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Novel non-uniform distribution of serotonin transporter in the mouse hippocampus and neocortex revealed by N-and C-terminal domain-specific immunohistochemistry2006
- Author(s)
  Shigematsu N, Yamamoto K, Higuchi S, Fukuda T.
- Journal Title
  
  Brain Res. 1075
  
  Pages: 110-116
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure2006
- Author(s)
  Hashimoto M, Kadowaki T, Tsukuba T., Yamamoto K.
- Journal Title
  
  J.Biochem. 140
  
  Pages: 713-723
- NAID
  10018841154
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase2006
- Author(s)
  Naito, M, Sakai, E, Shi, Y, Ideguchi, H, Shoji, M, Ohara, N, Yamamoto, K, Nakayama, K
- Journal Title
  
  Mol Microbiol 59
  
  Pages: 152-67
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Gingipains inactivate a cell surface ligand on Porphyromonas gingivalis that induces TLR2-and TLR4-independent signaling2006
- Author(s)
  Kishimoto, M, Yoshimura, A, Naito, M, Okamoto, K, Yamamoto, K, Golenbock, DT, Hara, Y, Nakayama, K
- Journal Title
  
  Microbiol Immunol 50
  
  Pages: 315-325
- NAID
  10018119237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Gingipains inactivate a cell surface ligand on Porphyromonas gingival is that induces TLR2-and TLR4-independent signaling2006
- Author(s)
  Kishimoto M, Yoshimura A, Naito M, Okamoto K, Yamamoto K, Golenbock DT, Hara Y, Nakayama K.
- Journal Title
  
  Microbiol Immunol. 50
  
  Pages: 315-325
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Up-regulation, and enhanced maturation and secretion of cathepsin E in mouse macrophages treated with interferon-γ or lipopolysaccharide2006
- Author(s)
  Yanagawa, M, Tsukuba, T, Okamoto, K, Terada, Y, Kadowaki, T, Yamamoto, K
- Journal Title
  
  J. Oral Biosci 48
  
  Pages: 218-225
- NAID
  10018041983
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors2006
- Author(s)
  Tsukuba, T, Yamamoto, S, Yanagawa, M, Okamoto, K, Okamoto, K, Nakayama, KI, Kadowaki, T, Yamamoto, K
- Journal Title
  
  J. Biochem 140
  
  Pages: 57-66
- NAID
  10018843713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors2006
- Author(s)
  Tsukuba T., Yamamoto S., Yanagawa M., Okamoto K, Okamoto K., Nakayama KI, Kadowaki T, Yamamoto K.
- Journal Title
  
  J.Biochem. 140
  
  Pages: 57-66
- NAID
  10018843713
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder in macrophages showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH2006
- Author(s)
  Yanagawa M^*., Tsukuba T^*., Nishioku T, Okamoto Y. Okamoto K., Takii R., Terada Y, Nakayama KI., Kadowaki T, Yamamoto K.
- Journal Title
  
  J.Biol Chem. 282
  
  Pages: 1851-1862
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase2006
- Author(s)
  Naito M, Sakai E, Shi Y, Ideguchi H, Shoji M, Ohara N, Yamamoto K, Nakayama K.
- Journal Title
  
  Mel Microbiol. 59
  
  Pages: 152-67
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycoSylation expressed in human embryonic kidney 293T cells2006
- Author(s)
  Tsukuba, T, Ikeda, S, Okamoto, K, Yasuda, Y, Sakai, E, Kadowaki, T, Sakai, H, Yamamoto, K
- Journal Title
  
  FEBS J 273
  
  Pages: 219-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors.2006
- Author(s)
  Tsukuba T., Yamamoto S., et al.
- Journal Title
  
  J. Biochem. 140巻
  
  Pages: 57-66
- NAID
  10018843713
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Up-regulation,and enhanced maturation and secretion of cathepsin E in mouse macrophages treated with interferon-y or lipopolysaccharide2006
- Author(s)
  Yanagawa M., Tsukuba T, Okamoto K., Terada Y, Kadowaki T, Yamamoto K
- Journal Title
  
  J.Oral Biosci. 48
  
  Pages: 218-225
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation expressed in human embryonic kidney 293T cells2006
- Author(s)
  Tsukuba T., Ikeda S., Okamoto K. Yasuda Y, Sakai E, Kadowaki T., Sakai H., Yamamoto K.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Novel non-uniform distribution of serotonin transporter in the mouse hippocampus and neocortex revealed by N- and C-terminal domain-specific immunohistochemistry2006
- Author(s)
  Shigematsu, N, Yamamoto, K, Higuchi, S, Fukuda, T
- Journal Title
  
  Brain Res 1075
  
  Pages: 110-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Inhibition of Angiogenesis, Tumor Growth, and metastasis by Cathepsin E2004
- Author(s)
  K.Yamamoto
- Journal Title
  
  Exp.Med. 22
  
  Pages: 213-219
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Inhibition of Angiogenesis, Tumor Growth, and metastasis by Cathepsin E2004
- Author(s)
  Yamamoto, K.
- Journal Title
  
  Exp.Med.
  
  Pages: 213-219
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Periodontal Diseases and Pathogenic Proteinases2003
- Author(s)
  Yamamoto, K.
- Journal Title
  
  J.Med.Technol.
  
  Pages: 849-858
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Protease Diseases : Molecular Basis and Therapeutic Strategies2003
- Author(s)
  Yamamoto, K.
- Journal Title
  
  Folia Pharmacol.Jpn. 122
  
  Pages: 3-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Protease Diseases : Molecular Basis and Therapeutic Strategies2003
- Author(s)
  K.Yamamoto
- Journal Title
  
  Folia Pharmacol.Jpn. 122
  
  Pages: 3-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] プロテアーゼ疾患の分子病態と治療戦略2003
- Author(s)
  山本健二
- Journal Title
  
  日本薬理学会誌 122
  
  Pages: 3-4
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Periodontal Diseases and Pathogenic Proteinases2003
- Author(s)
  K.Yamamoto
- Journal Title
  
  J.Med.Technol. 47
  
  Pages: 849-858
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Two Virulent Proteinases Involved in Periodontal Disease Progression.2002
- Author(s)
  Yamamoto, K.
- Journal Title
  
  KASEAA
  
  Pages: 72-74
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] New Functional Aspects of Aspartic Proteinases.2001
- Author(s)
  Yamamoto, K.
- Journal Title
  
  J.Clin.Exp.Med.
  
  Pages: 23-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Pathophysiological Roles of Two Types of Gingipains in Periodontal Diseases.2001
- Author(s)
  Yamamoto, K.
- Journal Title
  
  Protein, Nucleic Acid and Enzyme
  
  Pages: 1781-1788
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Periodontopathogenic Proteinases.2001
- Author(s)
  Yamamoto, K.
- Journal Title
  
  Enigma of Proteolysis
  
  Pages: 132-142
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Patent] カテプシン E の腫瘍マーカーとしての用途およびカテプシン E ならびにカテプシン D の腫瘍血管新生阻害療法としての用途2010
- Inventor(s)
  山本健二、岩田淳一
- Industrial Property Rights Holder
  山本健二、岩田淳一
- Acquisition Date
  2010-02-12
- Data Source
  KAKENHI-PROJECT-22390350
[Patent] カテプシンEの腫瘍マーカーとしての用途及びカテプシンEならびにカテプシンDの腫瘍血管新生阻害療法のターゲットとしての用途2010
- Inventor(s)
  山本健二、岩田淳一
- Industrial Property Rights Holder
  山本健二、岩田淳一
- Filing Date
  2010-02-12
- Acquisition Date
  2010-02-12
- Data Source
  KAKENHI-PROJECT-19209058
[Patent] 新規ペプチド及びその使用2010
- Inventor(s)
  西垣功一、北村幸一郎、Madhu Biyani、二上雅恵、山本健二、川久保友世、安河内篤
- Industrial Property Rights Holder
  西垣功一、北村幸一郎、Madhu Biyani、二上雅恵、山本健二、川久保友世、安河内篤
- Industrial Property Number
  2009-245763
- Filing Date
  2010-03-17
- Acquisition Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-19209058
[Patent] アンチエイジング剤2009
- Inventor(s)
  山本健二、川久保友世、安河内篤
- Industrial Property Rights Holder
  山本健二、川久保友世、安河内篤
- Industrial Property Number
  2009-264894
- Filing Date
  2009-11-20
- Acquisition Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-19209058
[Patent] 新規な抗癌カテプシン製剤およびそれを用いた癌併用療法抗癌剤2007
- Inventor(s)
  山本健二、川久保友世、安河内篤
- Industrial Property Rights Holder
  山本健二、川久保友世、安河内篤
- Industrial Property Number
  2008-500586
- Filing Date
  2007-02-19
- Acquisition Date
  2007-02-19
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Idetification of two transcripts and in vivo promoter analysis for cathepsin E2012
- Author(s)
  Okamoto K, Sakai E, Nishishita K, Yamamoto K, Tsukuba T.
- Organizer
  The 85^<th> Annual Meeting of Pharmacological Society
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E-induced growth arrest and apoptosis of cancer cells and the related signaling2012
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T.
- Organizer
  The 85^<th> Annual Meeting of Pharmacological Society
- Place of Presentation
  Kyoto
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Selection-by-Function 法によるプロテアーゼアクチベーターの開発2012
- Author(s)
  小松将之、北村幸一郎、Sunita Gautam, Madhu Biyani, 山本健二、西垣功一
- Organizer
  第17回日本病態プロテアーゼ学会
- Place of Presentation
  浜松
- Year and Date
  2012-08-10
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Idetification of two transcripts and in vivo promoter analysis for cathepsin E2012
- Author(s)
  Okamoto K, Sakai E, Nishishita K, Yamamoto K, Tsukuba T
- Organizer
  The 85^<th>Annual Meeting of Pharmacological Society
- Place of Presentation
  Kyoto
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Accumulation of NADPH oxidase (NOX2) and increased oxidative stress in cathepsin E-deficient macrophages2012
- Author(s)
  Tsukuba T, Kadowaki T, Okamoto K, Yamamoto K
- Organizer
  The 85^<th>Annual Meeting of Pharmacological Society
- Place of Presentation
  Kyoto
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E-induced growth arrest and apoptosis of cancer cells and the related signaling2012
- Author(s)
  Yamamoto K., Kawakubo T., Yasukochi A. Tsukuba T
- Organizer
  The 85^<th> Annual Meeting of Pharmacological Society
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Accumulation of NADPH oxidase (N0X2) and increased oxidative stress in cathepsin E-deficient macrophages2012
- Author(s)
  Tsukuba T., Kadowaki T., Okamoto K., Yamamoto K.
- Organizer
  The 85^<th> Annual Meeting of Pharmacological Society
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] カテプシンEによるガン細胞の増殖抑制とアポトーシス誘導および関連シグナリング2012
- Author(s)
  山本健二、川久保友世、安河内篤、筑波隆幸
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E: related signaling systems, functions and implication in diseases2012
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Okamoto K, Tsukuba T
- Organizer
  13th International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenia
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] カテプシンE遺伝子の発現機構の解析2012
- Author(s)
  岡元邦彰、岡本美子、坂井詠子、西下一久、山本健二、筑波隆幸
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] 反復流産病態における妊娠初期脱落膜中マクロファージの cathepsin E の役割2012
- Author(s)
  後藤志信、尾崎康彦、都筑佳苗、安河内篤、川久保友世、国松己歳、山本健二、杉浦真弓
- Organizer
  第17回日本病態プロテアーゼ学会
- Place of Presentation
  浜松
- Year and Date
  2012-08-10
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Selection-by-Function法によるプロテアーゼアクチベーターの開発2012
- Author(s)
  小松将之、北村幸一郎、Sunita Gautam, Madhu Biyani, 山本健二、西垣功一
- Organizer
  第17回日本病態プロテアーゼ学会
- Place of Presentation
  浜松
- Year and Date
  2012-08-10
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] 反復流産病態における妊娠初期脱落膜中マクロファージのcathepsin Eの役割2012
- Author(s)
  後藤志信、尾崎康彦、都筑佳苗、安河内篤、川久保友世、国松己歳、山本健二、杉浦真弓
- Organizer
  第17回日本病態プロテアーゼ学会
- Place of Presentation
  浜松
- Year and Date
  2012-08-10
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E : related signaling systems, functions and implication in diseases2012
- Author(s)
  Yamamoto K., Kawakubo T., Yasukochi A., Okamoto K., Tsukuba T
- Organizer
  13th International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  スロベニア
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] p53 はカテプシン E 遺伝子の発現を制御する2012
- Author(s)
  岡元邦彰、岩田淳一、坂井詠子、西下一久、山本健二、筑波隆幸
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] p53はカテプシンE遺伝子の発現を制御する2012
- Author(s)
  岡元邦彰、岩田淳一、坂井詠子、西下一久、山本健二、筑波隆幸
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] カテプシンE欠損マクロファージにおけるNADPH oxidase (NOX2)の蓄積と酸化ストレスの増加2012
- Author(s)
  筑波隆幸、門脇知子、岡元邦彰、山本健二
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] カテプシンE結合ペプチド群を例としたP2p (Protei-topeptide)研究展開-「副作用のない創薬」を目指して-2011
- Author(s)
  北村幸一郎、Biyani Madhu、二上雅恵、相田拓洋、後藤仁志、小松将之、川久保友世、鈴木美穂、山本健二、西垣功一
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] マウス皮膚表皮細胞における内在性カテプシンEの役割2011
- Author(s)
  安河内篤、川久保友世、中村誠司、山本健二
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] DMBA/TPA二段階乳頭腫形成モデルにおける表皮カテプシンEの役割2011
- Author(s)
  安河内篤、川久保友世、中村誠司、山本健二
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] DMBA/TPA二段階乳頭腫形成モデルにおける表皮カテプシンEの役割2011
- Author(s)
  安河内篤、川久保友世、中村誠司、山本健二
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Role of cathepsin E in deciduas of patients with recurrent miscarriage2011
- Author(s)
  Goto S, Ozaki Y, Kitaori T, Yasukochi A, Kawakubo T, Sugiura M, Yamamoto K
- Organizer
  7^<th> General Meeting of the International Proteolysis Society
- Place of Presentation
  San Diego (USA)
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] 反復流産病態における妊娠初期頸管粘液中Cathepsin Eの役割2011
- Author(s)
  後藤志信、尾崎康彦、大林勇輝、北折珠央、平光由衣乃、安河内篤、川久保友世、山本健二、杉浦真弓
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E is essential for proper mammogenesis2010
- Author(s)
  Kawakubo T, Yasukochi A, Yamamoto K
- Organizer
  12^<th> Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Novel functions of cathepsin E in epidermal differentiation and aging2010
- Author(s)
  Kawakubo T, Yasukochi A, Yamamoto K
- Organizer
  12^<th> Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Analysis of cathepsin E function in epidermal differentiation using a model of DMBA/TPA- induced skin papillomas2010
- Author(s)
  Yasukochi A, Kawakubo T, Yamamoto K
- Organizer
  12th Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Novel functions of cathepsin E in epidermal differentiation and aging2010
- Author(s)
  Yamamoto K
- Organizer
  12th International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenis
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Transcription factor Spl regulates the expression of the murine cathepsin E in gastric adenosarcoma cells2010
- Author(s)
  Okamoto K, Okamoto Y, Kawakubo T, Yamamoto K, Tsukuba T
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E: related signaling systems, functions and implication in diseases2010
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Okamoto K, Tsukuba T
- Organizer
  13th International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenis
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E is essential for proper mammogenesis2010
- Author(s)
  Kawakubo T, Yasukochi A, Yamamoto K
- Organizer
  12th Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Analysis of cathepsin E function in epidermal differentiation using a model of DMBA/TPA-induced skin papillomas2010
- Author(s)
  Yasukochi A, Kawakubo T, Yamamoto K.
- Organizer
  12^<th> Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] カテプシンEの機能と疾患および治療を目指して2008
- Author(s)
  山本健二
- Organizer
  日本病態プロテアーゼ学会
- Place of Presentation
  大阪
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Cathepsin E in tumor progression and bacterial infection2008
- Author(s)
  Yamamoto K, et al.
- Organizer
  11^<th> International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Slovenia
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Roles for gingipains in atherosclerosis progression accelerated by bacterial exposure2007
- Author(s)
  Kadowaki T, Takii R, Hashimoto M, Yamatake K, Tsukuba T, Yamamoto K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras,Greece
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] 「研究成果報告書概要(欧文)」より2007
- Author(s)
  Yamamoto, K, Tsukuba, T, Yanagawa, M, kakehashi, H, Kawakubo, T, Kadowaki, T
- Organizer
  10th International Symposium on Protease Inhibitor and Biological Control
- Place of Presentation
  Portoroz, Slovenia
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] P.gingivalis感染とインスリン抵抗性に関する実験的解析2007
- Author(s)
  門脇知子, 瀧井良祐, 筑波隆幸, 岡元邦彰, 山本健二
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles for gingipains in atherosclerosis progression accelerated by bacterial exposure2007
- Author(s)
  Kadowaki, T, Takii, R, Hashimoto, M, Yamatake, K, Tsukuba, T, Yamamoto, K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] The role of cathepsin E in immune responses mediated by macrop hages2007
- Author(s)
  Yamamoto K.
- Organizer
  Special lecture for Windeyer Institute of Medical Sciences
- Place of Presentation
  Devision of Infection & Immunity,University College of London
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] ASSOCIATION OF CATHEPSIN E WITH HOST DEFFENCE AGAINST TUMOR CELLS.(Symposium2007
- Author(s)
  Kawakubo, T, Yasukochi, A, Okamoto, K, Y, Okamoto, Y, Kadowaki, T, Tsukuba, T, Yamamoto, K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] ASSOCIATION OF CATHEPSIN E WITH HOST DEFFENCE A GAINST TUMOR CELLS,(Symposium)2007
- Author(s)
  Kawakubo T, Yasukochi A, Okamoto K, Y Okamoto Y, Kadowaki T, Tsukuba T, Yamamoto K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras,Greece
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E differentially regulates the nature and functions of macrop hages and dendritic cells2007
- Author(s)
  山本健二, 他
- Organizer
  Xthe International Symposium on Protsinase Inhibitors and Biological Control
- Place of Presentation
  スロベニア
- Year and Date
  2007-07-23
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] P.gingivalis感染による生活習慣病増悪に関する基礎的研究2007
- Author(s)
  門脇知子, 瀧井良祐, 重松直樹, 筑波隆幸, 山本健二
- Organizer
  第2回口腔健康科学シンポジウム
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンE欠損はマクロファージの膜蛋白質輸送異常とミトコンドリア機能異常を起こす2007
- Author(s)
  筑波隆幸, 柳川三千代, 岡元邦彰, 岡本美子, 門脇知子, 山本健二
- Organizer
  第30回日本分子生物学会/第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンE欠損によるミトコンドリア機能異常と酸化ストレス亢進2007
- Author(s)
  筑波隆幸, 柳川三千代, 岡元邦彰, 門脇知子, 山本健二
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E exerts tumoricidal activity through generation of soluble TRAIL from the tumor cell surface2007
- Author(s)
  Kawakubo T, Kadowaki T, Tsukuba T, Yamamoto K
- Organizer
  第59回日本細胞生物学会大会
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] 歯周病研究の最前線-病態解明・治療を目指して2007
- Author(s)
  山本健二
- Organizer
  平成19年度福岡市歯科医師会学術講演会特別講演
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles of cathepsin E in immune responses mediated by macrophages and dendritic cells2007
- Author(s)
  Yamamoto K., Tsukuba T., Yanagawa M., Kakehashi H., Kawakubo T., Kadowaki T
- Organizer
  10th International Symposium on Protease Inhibitor and Biological Control
- Place of Presentation
  Portoroz,Slovenia
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] CONTROL OF THE ENDOSOME/LYSOSOME SYSTEM OF MACROPHAGES BY CATHEPSIN E2007
- Author(s)
  Tsukuba, T, Okamoto, K, Kadowaki, K, Yamamoto, K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] CONTROL OF THE ENDOSOME/LYSOSOME SYSTEM OF MACR OPHAGES BY CATHEPSIN E2007
- Author(s)
  Tsukuba T, Okamoto K, Kadowaki K, Yamamoto K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras,Greece
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] 赤血球におけるカテプシンEの役割2007
- Author(s)
  岡元邦彰, 石田豊, 坂井詠子, 西下一久, 山本健二, 筑波隆幸
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] 血管新生抑制と生体防御能増強によるカテプシンEの腫瘍抑制2007
- Author(s)
  進正史, 門脇知子, 川久保友世, 瀧井良祐, 筑波隆幸, 山本健二
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  宮崎
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E mediates membrane trafficking in macrophages2007
- Author(s)
  Tsukuba T, Yamamoto S, Yanagawa M, Okamoto Y, Okamoto K, Yamamoto K
- Organizer
  第80回日本薬理学会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] 歯周病と動脈硬化2007
- Author(s)
  山本健二
- Organizer
  平成19年度博多区医師会学術講演会特別講演
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E acts as an inhibitor of tumor cells2006
- Author(s)
  Shin M., Kadowaki T., Kawakubo T, Tsukuba, T, Yamamoto K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
- Place of Presentation
  Awaji,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Suppression of carcinogennsis and tumor growth by cathepsin E2006
- Author(s)
  Kawakubo, T, Okamoto, K, Okamoto, Y, Tsukuba, T, Yamamoto, K
- Organizer
  20th IUBMB Congress of Biochemistry and Molecular Biology and FAOBMB Congress
- Place of Presentation
  Kyoto Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles of cathepsin E in immune responses mediated by macrophages.(Symposium)2006
- Author(s)
  Tsukuba, T, Yanagawa, M., Yamamoto S., Kadowaki T., Yamamoto K.
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors, Satellite Meeting of the 20th IUBMB Congress
- Place of Presentation
  Awaji,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Suppression of carcinogenesis and tumor growth by cathepsin E2006
- Author(s)
  Kawakubo T, Okamoto K., Okamoto Y., Tsukuba, T, Yamamoto K
- Organizer
  the 20th IUBMB Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congres
- Place of Presentation
  Kyoto Japan.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] A possible mechanism for cathepsin-E mediated tumor suppression2006
- Author(s)
  Kawakubo T, Okamoto K., Okamoto Y., Tsukuba, T, Yamamoto K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
- Place of Presentation
  Awaji,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] A possible mechanism for cathepsin-E mediated tumor suppression2006
- Author(s)
  Kawakubo, T, Okamoto, K, Okamoto, Y, Tsukuba, T, Yamamoto, K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
- Place of Presentation
  Awaii, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンE欠損マクロファージにおける膜タンパク質の輸送異常2006
- Author(s)
  筑波隆幸、山本晋也、柳川三千代、岡元邦彰、門脇知子、山本健二
- Organizer
  第48回歯科基礎医学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Porphyromonas gingivalisの生活習慣病増悪機構について2006
- Author(s)
  門脇知子、筑波隆幸、瀧井良佑、重松直樹、岡元邦彰、山本健二
- Organizer
  第48回歯科基礎医学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles of cathepsin E in immune responses mediated by macrophages.(Symnosium)2006
- Author(s)
  Tsukuba, T, Yanagawa, M, Yamamoto, S, Kadowaki, T, Yamamoto, K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors, Satellite Meeting of the 20th IUBMB Congress
- Place of Presentation
  Awaji, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E acts as an inhibitor of tumor cells2006
- Author(s)
  Shin, M, Kadowaki, T, Kawakubo, T, Tsukuba, T, Yamamoto, K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
- Place of Presentation
  Awaji, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンEの過剰発現による腫瘍抑制効果2006
- Author(s)
  進正史、門脇知子、川久保友世、筑波隆幸、山本健二
- Organizer
  第59回日本薬理学会西南部会
- Place of Presentation
  那覇
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038

1. NAKANISHI Hiroshi (20155774)

# of Collaborated Projects: 19 results

# of Collaborated Products: 0 results
2. TSUKUBA Takayuki (30264055)

# of Collaborated Projects: 13 results

# of Collaborated Products: 69 results
3. KADOWAKI Tomoko (70336080)

# of Collaborated Projects: 10 results

# of Collaborated Products: 77 results
4. 坂井英昭 (40225769)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. KAWAKUBO Tomoyo (70507813)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
6. KATO Yuzo (20014128)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. AKAMINE Akifumi (00117053)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. OKAMOTO Kuniaki (10311846)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
9. TAKII Ryosuke (00419558)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
10. HORI Nobuaki (60037520)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. YAMAMOTO Miho (50191341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KAMATA Osamu (80037580)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. UENO Eiko (10176612)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. YAMAATAAKE Kumiko (50622114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. AOKI Yosuke (80049030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IKAI Atsushi (50011713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KATO Ihachi (30005087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. EZAKI Mitsue (30223647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KUNIMATSU Kazushi (20170011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAYAMA Koji (80150473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NAKAYAMA Hiroaki (70047744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 朔敬 (40145264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 後藤康治 (00170473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 金井貞

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 浅尾哲次

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. TETSUJI Asao

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 浅尾哲治

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAMOTO Kenji 山本 健二

山本 建二 ヤマモト ケンジ

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Relationship between periodontal disease and systemic diseases: molecular mechanisms and novel therapy discoveryPrincipal Investigator

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蛋白質高速分子進化技術による歯周病の分子標的治療薬及び早期診断キットの開発Principal Investigator

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Protease-mediated regulation of host immune system and application as therapeutic targetsPrincipal Investigator

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生体防御系におけるプロテアーゼの機能解析Principal Investigator

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Molecular basis of host immune responses to periodontal diseasePrincipal Investigator

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歯周病における免疫制御系プロテアーゼの機能解析Principal Investigator

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ESTABLISHMENT OF A CLINICAL TREATMENT SYSTEM FOR PERIODONTAL DISEASEPrincipal Investigator

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神経系におけるオートファジー・リソソームシステムPrincipal Investigator

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エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割Principal Investigator

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MOLECULAR BASIS OF PROTEINASE FUNCTION IN PROGRESSION OF PERIODONTAL DISEASESPrincipal Investigator

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YAMAMOTO Kenji 山本健二

山本建二ヤマモトケンジ