AKIZAWA TADAO 秋澤忠男

… Alternative Names

AKIZAWA Tadao 秋澤忠男

秋澤忠男アキザワタダオ

秋沢忠男アキサワタダオ

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Researcher Number	40102339
Other IDs
Affiliation (Current)	2025: 昭和医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2006 – 2010: 昭和大学, 医学部, 教授 2002 – 2005: 和歌山県立医科大学, 医学部, 教授 1999: WAKAYAMA MEDICAL UNIVERSITY, DEPARTMENT OF MEDICINE, PROFESSOR, 医学部, 教授 1998: 昭和大学, 医学部, 助教授 1996: 昭和大学, 医学部, 助教授 … More 1995: SYOUWA UNIVERSITY SCHOOL OF MEDICINE,FUJIGAOKA HOSPITAL,DIVISION OF NEPHOLOGY,AS, 医学部・藤が丘病院腎臓内科, 助教授 1994 – 1995: 昭和大学, 医学部・藤が丘病院・腎臓内科, 助教授 1992: 昭和大学, 医学部, 助教授 1991: 昭和大学, 藤ヶ丘病院・内科, 助教授 1986 – 1987: 昭和大学, 医学部内科, 助手 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine Except Principal Investigator 内科学一般 / Kidney internal medicine / Biomedical engineering/Biological material science
Keywords	Principal Investigator 2次性副甲状腺機能亢進症 / calcimimetics / 異所性石灰化 / 腎性骨異栄養症 / Vitamin D / Secondary hyperparathyroidism / ビタミンD / 活性型ビタミンD / 副甲状腺ホルモン / カルシウム受容体 … More / 線維性骨炎 / 動脈硬化 / 慢性腎不全 / 二次性副甲状腺機能亢進症 / apoptosis / secondary hyperparathyroidism / vitamin D receptor / Osteitis fibrosa / Parathyroid hormone / Calcium / Phosphorus / Ectopic vascular calcification / Renal osteodystrophy / 副甲状腺機能低下症 / 無形成骨 / アポトーシス / カルシウム受容体作動薬 / 副甲状線ホルモン / カルシウム / リン / 異所性血管石灰化 / Calcimimetics / Phosphate / Atherosclerosis / Vascular calcification / Ectopic calcification / Chronic renal failure / sodium-dependent phosphate cotransporter / osteopontin / core binding factor-alpha 1(Cbfa1) / リン吸着薬 / 血管石灰化 / APOPTOSIS / CALCIMIMETICS / VITAMIN D RECEPTOR / CALCIUM SENSING RECEPTOR / ACTIVE VITAMIN D / PARATHYROID HORMONE / SECONDARY HYPERPARATHYROIDISM / RENAL OSTEODYSTROPHY / calciumimetics / vitamin D receptro / Calcium sensing receptor / 活性型ビタミンDアナログ / calcium sensing receptor / 副甲状腺ホルモン(PTH) / lipid metabolism / osteitis fibrosa / blood pressure / Ca-sensing receptor / renal failure / カルシウム受容体アゴニスト / 副甲状腺 / ビタミンD受容体 / 糸球体硬化 / 脂質代謝 / 血圧 / 腎不全 / bisphosphonate / カルシウム受容作動薬 / CKD-MBD / エラスチン / 慢性炎症 / 慢性腎臓病ミネラル骨代謝異常症 / chronic renal failure / diffuse hyperplasia / nodular hyperplasia / primary hyperparathyroidism / Ca sensing reseptor … More Except Principal Investigator 血液適合性 / in situ hybridization / リン脂質ポリマー / タンパク質吸着 / superoxide / Leucotrien / Thromboxane / Prostaglandin / Anaphylatoxin / Complement-receptor / Complement / Biomaterial / Biocompatibility / リンパ球補体レセプター / モノクロナル抗体 / プロスタグランディン / アナフィラトキシン / 活性酸素 / ロイコトリエン / トロンボキサン / ブロスタグランディン / β_2ミクログロブリン / 補体レセプター / 補体 / 合成材料 / 生体適合性 / Vitamin D analog / Suppression Subtractive Hybridization / chief cell / parathyroid-specific gene / Parathyroid hormone / Secondary hyperparathyroidism / クローニング / Supression Substractive hybrization法 / in situ hybridization法 / Supression substructive hybrization法 / 副甲状腺増殖 / 抗体作製 / Supression substructive hybization法 / 新規副甲状腺特異遺伝子 / 二次性副甲状腺機能亢進症 / Artificail Kidney / Complement Activation / Protein Adsorption / Platelet Adhesion / Phospholipid Polymer / Nonthrombogenicity / Hemocompatibility / Hemodialysis Membrane / 表面修飾 / 補体活性 / 血液透析 / 人工腎臓 / 補体活性化 / 血小板粘着 / 抗血栓性 / 血液透析膜 / 血小板 / 細胞粘着 / 組織化構造 / 人工臓器 / タンパク質の吸着 / 医用材料 / 細胞機能 / 脂質 / 組織化吸着 / 医用高分子 / 生体膜 / リン脂質高分子 Less

Experimental study for the regression of chronic kidney disease and mineral bone disorder(CKD-MBD)Principal Investigator
- Principal Investigator
  
  AKIZAWA Tadao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
Cross talk between the onset of renal osteodystrophy and ectopic vascular calcificationPrincipal Investigator
- Principal Investigator
  
  AKIZAWA Tadao
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
Effect of renal hyperparathyroidism on the vascular calcification in uremic rats.Principal Investigator
- Principal Investigator
  
  AKIZAWA Tadao
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Wakayama Medical University
THE ANALYSIS OF ADENOVO GENE IS EXPRESSED WITH SECONDARY HYPERPARATHYROIDISM
- Principal Investigator
  
  NEGI Shigeo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Wakayama Medical University
Pathogenesis and control of renal osteodystrophyPrincipal Investigator
- Principal Investigator
  
  AKIZAWA Tadao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Wakayama Medical University
EFFECT OF Ca-SENSING RECEPTOR ACTIVATION ON UREMIAPrincipal Investigator
- Principal Investigator
  
  AKIZAWA Tadao
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  WAKAYAMA MEDICAL UNIVERSITY
  Showa University
二次性副甲状腺機能亢進症におけるCa受容体、VD受容体異常とその相互作用Principal Investigator
- Principal Investigator
  
  秋澤忠男
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
PREPARATION OF NONTOROMBOGENICHEMODIALYZER AND ITS PRECLINICAL EVALUATION
- Principal Investigator
  
  ISHIHARA Kazuhiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  INSTITUTE FORR MEDICAL AND DENTAL ENGINEERING,TOKYO MEDICAL AND DENTAL UNIVERSITY
生体分子組織性ポリマーによる細胞機能制御とその医用デバイス化
- Principal Investigator
  
  石原一彦
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
リン脂質組織化による生体膜類似表面の生成過程を伴う細胞機能の制御に関する研究
- Principal Investigator
  
  ISHIHARA Kazuhiko
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
The Pathophysiological Significance of Changes in Plasma Bioactive Substances Induced by Biomaterials
- Principal Investigator
  
  KOSHIKAWA Shozo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Showa University

All 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Mineral Metabolism Management in Hemodialysis Patients with Secondary Hyperparathyroidism in Japan : Baseline Data from the MBD-5D.2011
- Author(s)
  Fukagawa M, Komaba H, Onishi Y, Fukuhara S, Akizawa T, Kurokawa K
- Journal Title
  
  Am J Nephrol 33(5)
  
  Pages: 427-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Mineral and bone disorders outcomes study for Japanese chronic kidney disease stage 5D patients : rationale and study design.2011
- Author(s)
  Fukuhara S, Akizawa T, Fukagawa M, Onishi Y, Yamaguchi T, Hasegawa T, Kurokawa K
- Journal Title
  
  Ther Apher Dial. 15(2)
  
  Pages: 169-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Involvement of alpha-klotho and fibroblast growth factor receptor in the development of secondary hyperparathyroidism.2010
- Author(s)
  Kumata C, Mizobuchi M, Ogata H, Koiwa F, Nakazawa A, Kondo F, Kadokura Y, Kinugasa E, Akizawa T
- Journal Title
  
  Am J Nephrol. 31(3)
  
  Pages: 230-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Detection of peripheral artery disease by duplex ultrasonography among hemodialysis patients.2010
- Author(s)
  Ogata H, Kumata-Maeta C, Shishido K, Mizobuchi M, Yamamoto M, Koiwa F, Kinugasa E, Akizawa T
- Journal Title
  
  Clin J Am Soc Nephrol. 5(12)
  
  Pages: 2199-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Development of a technique for introduction of an expressed complementary deoxyribonucleic acid into parathyroid cells by direct injection.2010
- Author(s)
  Shiizaki K, Hatamura I, Fukagawa M, Nakazawa E, Saji F, Watanabe Y, Akizawa T, Kusano E
- Journal Title
  
  Endocrinology. 151(8)
  
  Pages: 4031-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Impact of fibroblast growth factor 23 on lipids and atherosclerosis in hemodialysis patients.2010
- Author(s)
  Ashikaga E, Honda H, Suzuki H, Hosaka N, Hirai Y, Sanada D, Nakamura M, Nagai H, Matsumoto K, Kato N, Mukai M, Watanabe M, Takahashi K, Shishido K, Akizawa T.
- Journal Title
  
  Ther Apher Dial. 14(3)
  
  Pages: 315-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Improvement of impaired calcium and skeletal homeostasis in vitamin D receptor knockout mice by a high dose of calcitriol and maxacalcitol.2009
- Author(s)
  Shiizaki K, Hatamura I, Imazeki I, Moriguchi Y, Sakaguchi T, Saji F, Nakazawa E, Kato S, Akizawa T, Kusano E
- Journal Title
  
  Bone. 45(5)
  
  Pages: 964-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Vitamin D and vascular calcification in chronic kidney disease.2009
- Author(s)
  Mizobuchi M, Ogata H, Koiwa F, Kinugasa E, Akizawa T
- Journal Title
  
  Bone. 45 Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] KRN1493 Study Group. Long-term cinacalcet HCl treatment improved bone metabolism in Japanese hemodialysis patients with secondary hyper-parathyroidism.2009
- Author(s)
  Shigematsu T, Akizawa T, Uchida E, Tsukamoto Y, Iwasaki M, Koshikawa S
- Journal Title
  
  Am J Nephrol. 29(3)
  
  Pages: 230-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Elastin degradation accelerates phosphate-induced mineralization of vascular smooth muscle cells.2009
- Author(s)
  Hosaka N, Mizobuchi M, Ogata H, Kumata C, Kondo F, Koiwa F, Kinugasa E, Akizawa T
- Journal Title
  
  Calcif Tissue Int. 85(6)
  
  Pages: 523-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Proliferating potential and apoptosis in the development of secondary hyperparathyroidism : a study based on Ki-67 immunohistochemical staining and the terminal dUTP nick-end labeling assay.2008
- Author(s)
  Wada Y, Kunimura T, Akizawa T, Moroboshi T, et, al
- Journal Title
  
  Ther Apher Dial 12
  
  Pages: 319-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Mortality risk for dialysis patients with different levels : the Dialysis Outcomes and Practice Patterns Study (DOPPS).2008
- Author(s)
  Tentori F, Blayney MJ, Albert JM, Gillespie BW, Kerr PG, Bommer J, Young EW, Akizawa T, Akiba T, Pisoni RL, Robinson BM, Port FK
- Journal Title
  
  Am J Kidney Dis. 52(3)
  
  Pages: 519-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Molecular and morphological approach of uremia-induced hyperplastic parathyroid gland following direct maxacalcitol injection.2008
- Author(s)
  Shiizaki K, Hatamura I, Akizawa T, et al
- Journal Title
  
  Med Mol Morphol. 41
  
  Pages: 76-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Highly Concentrated Calcitriol and its Analogues Induce Apoptosis of Parathyroid Cells and Regression of the Hyperplastic Gland Study in Rats2008
- Author(s)
  Shiizaki K, Hatamura I, Negi S, Sakaguchi T, Saji F, Imazeki I, Kusano E, Shigematsu T, Akizawa T.
- Journal Title
  
  Nephrol Dial Transplant 23(5)
  
  Pages: 1529-1536
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Direct injection of calcitriol or its analog improves abnormal gene expression in the hyperplastic parathyroid gland in uremia2008
- Author(s)
  Shiizaki K, Fukagawa M, Yuan Q, Hatamura I, Nii-Kono T, Saji F, Shigematsu T, Akizawa T.
- Journal Title
  
  Am J Nephrol. 28(1)
  
  Pages: 59-66
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Cinacalcet(KRN1493) effectively decreases the serum intact PTH level with favorable control of the serum phosphorus and calcium levels in Japanese dialysis patients2008
- Author(s)
  Fukagawa M, Akizawa T., et. al.
- Journal Title
  
  Nephrol Dial Transplant. Jan;23(1)
  
  Pages: 328-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Proliferating potential and apoptosis in the development of secondary hyperparathyroidism : a study based on Ki-67 immunohistochemical staining and the terminal dUTP nick-end labeling assay.2008
- Author(s)
  Wada Y, Kunimura T, Sato S, Hisayuki T, Sato M, Imataka H, Yamashita N, Akizawa T, Moroboshi T
- Journal Title
  
  Ther Apher Dial. 12(4)
  
  Pages: 319-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Direct injection of calcitriol or its analog improves abnormal gene expression in the hyperplastic parathyroid gland in uremia2008
- Author(s)
  Shiizaki K, Akizawa T., et. al.
- Journal Title
  
  Am J Nephrol. 28(1)
  
  Pages: 59-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Highly concentrated calcitriol and its analogues induce apoptosis of parathyroid cells and regression of the hyperplastic gland--study in rats.2008
- Author(s)
  Shiizaki K, Hatamura I, Negi S, Sakaguchi T, Saji F, Imazeki I, Kusano E, Shigematsu T, Akizawa T
- Journal Title
  
  Nephrol Dial Transplant. 23(5)
  
  Pages: 1529-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Highly Concentrated Calcitriol and its Analogues Induce Apoptosis of Parathyroid Cells and Regression of the Hyperplastic Gland Study in Rats2008
- Author(s)
  Shiizaki K, Akizawa T., et. al.
- Journal Title
  
  Nephrol Dial Transplant. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Molecular and morphological approach of uremia-induced hyperplastic parathyroid gland following direct maxacalcitol injection.2008
- Author(s)
  Shiizaki K, Hatamura I, Nakazawa E, Ogura M, Masuda T, Akizawa T, Kusano E
- Journal Title
  
  Med Mol Morphol. 41(2)
  
  Pages: 76-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Direct injection of calcitriol or its analog improves abnormal gene expression in the hyperplastic parathyroid gland in uremia.2008
- Author(s)
  Shiizaki K, Fukagawa M, Yuan Q, Hatamura I, Nii-Kono T, Saji F, Shigematsu T, Akizawa T
- Journal Title
  
  Am J Nephrol. 28(1)
  
  Pages: 59-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Clinical study of cinacalcet in Japan.2008
- Author(s)
  Akizawa T, Koshikawa S
- Journal Title
  
  Ther Apher Dial 12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Direct injection of calcitriol or its analog improves abnormal gene expression in the hyperplastic parathyroid gland in uremia2008
- Author(s)
  Shiizaki, K., Fukagawa, M., Yuan, Q., Hatamura, I., Nii-Kono, T., Saji, F., Shigematsu, T., Akizawa, T
- Journal Title
  
  Am J Nephrol 28(1)
  
  Pages: 59-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Highly Concentrated Calcitriol and its Analogues Induce Apoptosis of Parathyroid Cells and Regression of the Hyperplastic Gland Study in Rats2008
- Author(s)
  Shiizaki, K., Hatamura, I., Negi, S., Sakaguchi, T., Saji, F., Imazeki, I., Kusano, E., Shigematsu, T., Akizawa, T
- Journal Title
  
  Nephrol Dial Transplant 23(5)
  
  Pages: 1529-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] K Study Group. Impact of cinacalcet hydrochloride on bone histology in patients with secondary hyperparathyroidism.2008
- Author(s)
  Yajima A, Akizawa T, Tsukamoto Y, Kurihara S, Ito A
- Journal Title
  
  Ther Apher Dial. 12 Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Journal Article] Bingding of highly concentrated maxacalcitol to the nuclear vitamin D receptors of parathyroid cells.2007
- Author(s)
  Shiizaki K, Akizawa T, et al.
- Journal Title
  
  Nephrol Dial Transplant 22(In press)
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] CKD-MBD:impact on management of kidney disease2007
- Author(s)
  Ogata H, Akizawa T., et. al.
- Journal Title
  
  Clin Exp Nephrol. Dec;11(4)
  
  Pages: 261-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Binding of highly concentrated maxacalcitol to the nuclear vitamin D receptors of parathyroid cells2007
- Author(s)
  Shiizaki K, Hayakawa N, Imazeki I, Hatamura I, Okada T, Negi S, Sakaguchi T, Shigematsu T, Akizawa T.
- Journal Title
  
  Nephrol Dial Transplant. 22(4)
  
  Pages: 1078-1086
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Binding of highly concentrated maxacalcitol to the nuclear vitamin Dreceptors of parathyroid cells2007
- Author(s)
  Shiizaki K, Akizawa T., et. al.
- Journal Title
  
  Nephrol Dial Transplant. Apr;22(4)
  
  Pages: 1078-1086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Combination therapy with an angiotensin-converting enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats2007
- Author(s)
  Mizobuchi, M., Morrissey, J., Finch, JL., Martin, DR., Liapis, H., Akizawa, T. Slatopoisky, E
- Journal Title
  
  J Am Soc Nephrol 18(6)
  
  Pages: 1796-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Activation of calcium-sensing receptor accelerates apoptosis in hyperplastic parathyroid cells2007
- Author(s)
  Mizobuchi M, Ogata H, Hatamura I, Saji F, Koiwa F, Kinugasa E, Koshikawa S, Akizawa T
- Journal Title
  
  Biochem Biophys Res Commun. 12;362(1)
  
  Pages: 11-16
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Activation of calcium-sensing receptor accelerates apoptosis in hyperplastic parathyroid cells2007
- Author(s)
  Mizobuchi, M., Ogata, H., Hatamura, I., Saji, F., Koiwa, F., Kinugasa, E., Koshikawa, S., Akizawa, T
- Journal Title
  
  Biochem Biophys Res Commun 362(1)
  
  Pages: 11-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Binding of highly concentrated maxacalcitol to the nuclear vitamin D receptors of parathyroid cells2007
- Author(s)
  Shiizaki, K., Hayakawa, N., Imazeki, I., Hatamura, I., Okada, T., Negi, S., Sakaguchi, T., Shigematsu, T., Akizawa, T
- Journal Title
  
  Nephrol Dial Transplant 22(4)
  
  Pages: 1078-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Combination therapy with an angiotensin-converting enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats2007
- Author(s)
  Mizobuchi M, Morrissey J, Finch JL, Martin DR, Liapis H, Akizawa T,
- Journal Title
  
  J Am Soc Nephrol. 18(6)
  
  Pages: 1796-1806
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Hypercalcaemia is associated with poor mental health in haemodialvsis patients : results from Japan DOPPS.2007
- Author(s)
  Tanaka M, Akizawa T, et al.
- Journal Title
  
  Nephrol Dial Transplant 22(In press)
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Association of mineral metabolism factors with all-cause and cardiovascular mortality in Liemodialysis patients:the Japan dialysis outcomes and practice patterns study2007
- Author(s)
  Kimata N, Akizawa T., et. al.
- Journal Title
  
  Hemodial Int. Jul;11(3)
  
  Pages: 340-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Combination therapy with an angiotensin-converting enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats2007
- Author(s)
  Mizobuchi M, Akizawa T., et. al.
- Journal Title
  
  J Am Soc Nephrol. Jun;18(6)
  
  Pages: 1796-1806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Activation of calcium-sensing receptor accelerates apoptosis in hyperplastic parathyroid cells2007
- Author(s)
  Mizobuchi M, Akizawa T., et. al.
- Journal Title
  
  Biochem Biophys Res Commun. Oct12;362(1)
  
  Pages: 11-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Direct injection of calcitriol or its analog into hyperplastic parathyroid glands induces apoptosis of parathyroid cells.2006
- Author(s)
  Shiizaki K, Akizawa T, et al.
- Journal Title
  
  Kidney Int 70(Suppl.)
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Direct maxacalcitol injection into hyperplastic parathyroids improves skeletal changes in secondary hyperparathyroidism.2006
- Author(s)
  Shiizaki K, Akizawa T, et al.
- Journal Title
  
  Kidney Int 70(3)
  
  Pages: 486-95
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Does sevelamer have greater skeletal benefit than calcium carbonate in children with secondary hyperparathyroidism?2006
- Author(s)
  Akizawa T
- Journal Title
  
  Nat Clin Pract Nephrol. 2(3)
  
  Pages: 130-1
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Up-regulation of Cbfa1 and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism.2006
- Author(s)
  Mizobuchi M, Akizawa T, et al.
- Journal Title
  
  Nephrol Dial Transplant. 21(4)
  
  Pages: 911-916
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Direct maxacalcitol injection into hyperplastic parathyroids improves skeletal changes in secondary hyperparathyroidism2006
- Author(s)
  Shiizaki K, Hatamura I, Negi S, Sakaguchi T, Saji F, Kunimoto K, Okamoto M, Imazeki I, Muragaki Y, Akizawa T
- Journal Title
  
  Kidney Int.2006 70(3)
  
  Pages: 486-495
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Up-regulation of Cbfa 1 and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism2006
- Author(s)
  Mizobuchi M, Ogata H, Hatamura I, Koiwa F, Saji F, Shiizaki K, Negi S, Kinugasa E, Ooshima A, Koshikawa S, Akizawa T.
- Journal Title
  
  Nephrol Dial Transplant. 21(4)
  
  Pages: 911-916
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Up-regulation of Cbfa1 and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism.2006
- Author(s)
  Mizobuchi M, Akizawa T, et al.
- Journal Title
  
  Nephrol Dial Transplant 21(4)
  
  Pages: 911-6
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Does sevelamer have greater skeletal benefit than calcium carbonate in children with secondary hyperparathyroidism.2006
- Author(s)
  Akizawa T
- Journal Title
  
  Nature Clinical Practice Nephrology 2(3)
  
  Pages: 130-131
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Up-regulation of Cbfal and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism2006
- Author(s)
  Mizobuchi, M., Ogata, H., Hatamura, I., Koiwa, F., Saji, F., Shiizaki, K., Negi, S., Kinugasa, E., Ooshima, A., Koshikawa, S., Akizawa, T
- Journal Title
  
  Nephrol Dial Transplant 21(4)
  
  Pages: 911-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Direct maxacalcitol injection into hyperplastic parathyroids improves skeletal changes in secondary hyperparathyroidism2006
- Author(s)
  Shiizaki, K., Hatamura, I., Negi, S., Sakaguchi, T., Saji, F., Kunimoto, K., Okamoto, M., Imazeki, I., Muragaki, Y., Akizawa, T
- Journal Title
  
  Kidney Int 70(3)
  
  Pages: 486-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590909
[Journal Article] Direct maxacalcitol injection into hyperplastic parathyroids improves skeletal changes in secondary hyperparathyroidism2006
- Author(s)
  Shiizaki K, Akizawa T, et al.
- Journal Title
  
  Kidney Int 70(In press)
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Effect of MCI-196 (colestilan) as a phosphate binder on hyperphosphataemia in haemodialysis patients.2005
- Author(s)
  Kurihara S, Tsuruta Y, Akizawa T
- Journal Title
  
  Nephrol Dial Transplant. 20(2)
  
  Pages: 424-430
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Biochemical and Cellular Efects Direct Maxcalcitol Injection ParathyroidGland in Uremic Rats.2005
- Author(s)
  Shiizaki K, Negi, S, Hatamura I, Akizawa T et al.
- Journal Title
  
  J Am Soc Nephrol 16
  
  Pages: 97-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590856
[Journal Article] Predictors and consequences of altered mineral metabolism : The Dialysis Outcomes and Practice Patterns Study2005
- Author(s)
  Young EW, Albert JM, Akizawa T, Kurokawa K, et al.
- Journal Title
  
  Kidney Int. 67(3)
  
  Pages: 1179-1187
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Biochemical and cellular effects of direct maxacalcitol injection into parathyroid gland in uremic rats.2005
- Author(s)
  Shiizaki K, Akizawa T, et al.
- Journal Title
  
  J Am Soc Nephrol. 16(1)
  
  Pages: 97-108
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Biochemical and cellular effects of direct maxacalcitol injection into parathyroid gland in uremic rats.2005
- Author(s)
  Shiizaki K, Negi S, Ooshima A, Akizawa T, et al.
- Journal Title
  
  J Am Soc Nephrol. 16(1)
  
  Pages: 97-108
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Predictors and consequences of altered mineral metabolism : The Dialysis Outcomes and Practice Patterns Study2005
- Author(s)
  Young EW, Albert JM, Akizawa T, et al.
- Journal Title
  
  Kidney Int. 67(3)
  
  Pages: 1179-1187
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Effect of MCI-196 (colestilan) as a phosphate binder on hyperphosphataemia in haemodialysis patients : a double-blind, placebo-controlled, short-term trial.2005
- Author(s)
  Kurihara S, Tsuruta Y, Akizawa T.
- Journal Title
  
  Nephrol Dial Transplant. 20(2)
  
  Pages: 424-430
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] How to apply and adapt international guidelines on bone metabolism and disease to the management of Japanese dialysis patients.2005
- Author(s)
  Fukagawa M, Akizawa T
- Journal Title
  
  Ther Apher Dial. 9(1)
  
  Pages: 1-2
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] HMG-coenzyme a reductase inhibitor use is associated with mortality reduction in hemodialysis patients.2005
- Author(s)
  Mason NW, Akizawa T, et al.
- Journal Title
  
  Am J Kidney Dis. 45(1)
  
  Pages: 119-126
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Mineral metabolism and haemoglobin concentration among haemodialysis patients in the DOPPS.2005
- Author(s)
  Kimata N, Akizawa T, et al.
- Journal Title
  
  Nephrol Dial Transplant. 20(5)
  
  Pages: 927-935
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Mineral metabolism and haemoglobin concentration among haemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS).2005
- Author(s)
  Kimata N, Akizawa T, et al.
- Journal Title
  
  Nephrol Dial Transplant. 20(5)
  
  Pages: 927-935
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Calcimimetic compound upregulates decreased calcium-sensing receptor expression level in parathyroid glands of rats with chronic renal insufficiency2004
- Author(s)
  Mizobuchi M, Shiizaki K, Koshikawa S, Akizawa T et al.
- Journal Title
  
  J Am Soc Nephrol. 15(10)
  
  Pages: 2579-2587
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Calcimimetic compound upregulates decreased calcium-sensing receptor expression level in parathyroid glands of rats with chronic renal insufficiency2004
- Author(s)
  Mizobuchi M, Hatamura I, Negi S, Akizawa T. et al.
- Journal Title
  
  J Am Soc Nephrol 15
  
  Pages: 2579-2587
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590856
[Journal Article] The calcimimetic agent KRN 1493 lowers plasma parathyroid hormone and ionized calcium concentrations in patients with chronic renal failure.2004
- Author(s)
  Ohashi N, Togawa A, Akizawa T, Koshikawa S, et al.
- Journal Title
  
  Br J Clin Pharmacol. 57(6)
  
  Pages: 726-734
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Dose-response study of 22-oxacalcitriol in patients with secondary hyperparathyroidism.2004
- Author(s)
  Akizawa T, Ohashi Y, Akiba T, et al.
- Journal Title
  
  Ther Apher Dial. 8(6)
  
  Pages: 480-491
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Calcimimetic compound upregulates decreased calcium-sensing receptor expression level in parathyroid glands of rats with CRF2004
- Author(s)
  Mizobuchi M, Akizawa T, et al.
- Journal Title
  
  J Am Soc Nephrol 15(10)
  
  Pages: 2579-2587
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590797
[Journal Article] Percutaneous maxacalcitol injection therapy regresses hyperplasia of parathyroid and induces apoptosis in uremia.2003
- Author(s)
  Shiizaki K, Hatamura I, Negi, S, Akizawa T. et al.
- Journal Title
  
  Kidney Int.Sep 64(3)
  
  Pages: 992-1003
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590856
[Journal Article] Involvement of Matrix Metalloproteinase-2 in the Development of Medial Layer Vascular Calcification in Uremic Rats.
- Author(s)
  Chiaki Kumata, 1 Masahide Mizobuchi, Hiroaki Ogata, Fumihiko Koiwa, Fumiko Kondo, Eriko Kinugasa, Tadao Akizawa
- Journal Title
  
  Ther Apher Dial. 15(Supplement 1)
  
  Pages: 18-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590985
[Presentation] Both Type I Membrane Klotho and Fibroblast Growth Factor Receptor Are Decreased in Secondary Hyperparathyroidism2009
- Author(s)
  Tadao Akizawa
- Organizer
  American Society of Nephrology
- Place of Presentation
  SanDiego USA
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20590985
[Presentation] Effect of elastin degradation on the mineralization of vascular smooth muscle cells2008
- Author(s)
  Hosaka N, Mizobuchi M, Akizawa T, et. al
- Organizer
  米国腎臓学会
- Place of Presentation
  Philadelphia
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-20590985

1. OGATA Hiroaki (30296959)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
2. ISHIHARA Kazuhiko (90193341)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NEGI Shigeo (20208284)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. MIZOBUCHI Masahide (90465203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. WATANABE Akihiko (30126263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TANAKA Shinobu (40242218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAKAGUCHI Toshifumi (70343423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HATAMURA Ikuji (80336883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. SHIIZKI Kazuhiro (10423930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
10. KOSHIKAWA Shozo (20013873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMASHITA Yasuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AKIZAWA TADAO 秋澤 忠男

AKIZAWA Tadao 秋澤 忠男

秋澤 忠男 アキザワ タダオ

秋沢 忠男 アキサワ タダオ

Research Projects

Research Products

Co-Researchers

Experimental study for the regression of chronic kidney disease and mineral bone disorder(CKD-MBD)Principal Investigator

Principal Investigator

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Research Institution

Cross talk between the onset of renal osteodystrophy and ectopic vascular calcificationPrincipal Investigator

Principal Investigator

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Research Institution

Effect of renal hyperparathyroidism on the vascular calcification in uremic rats.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

THE ANALYSIS OF ADENOVO GENE IS EXPRESSED WITH SECONDARY HYPERPARATHYROIDISM

Principal Investigator

Project Period (FY)

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Research Institution

Pathogenesis and control of renal osteodystrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

EFFECT OF Ca-SENSING RECEPTOR ACTIVATION ON UREMIAPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

二次性副甲状腺機能亢進症におけるCa受容体、VD受容体異常とその相互作用Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

PREPARATION OF NONTOROMBOGENICHEMODIALYZER AND ITS PRECLINICAL EVALUATION

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

生体分子組織性ポリマーによる細胞機能制御とその医用デバイス化

Principal Investigator

Project Period (FY)

Research Category

Research Institution

リン脂質組織化による生体膜類似表面の生成過程を伴う細胞機能の制御に関する研究

Principal Investigator

Project Period (FY)

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Research Institution

The Pathophysiological Significance of Changes in Plasma Bioactive Substances Induced by Biomaterials

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Mineral Metabolism Management in Hemodialysis Patients with Secondary Hyperparathyroidism in Japan : Baseline Data from the MBD-5D.2011

Author(s)

Journal Title

Data Source

[Journal Article] Mineral and bone disorders outcomes study for Japanese chronic kidney disease stage 5D patients : rationale and study design.2011

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of alpha-klotho and fibroblast growth factor receptor in the development of secondary hyperparathyroidism.2010

AKIZAWA TADAO 秋澤忠男

AKIZAWA Tadao 秋澤忠男

秋澤忠男アキザワタダオ

秋沢忠男アキサワタダオ