TANAKA Kiyoko 田中貴代子

Researcher Number	40124474
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Affiliation *help	2012 : 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2011 : (財)東京都医学総合研究所, 研究員 2011 : (財)東京都医学総合研究所, 生体分子先端研究分野, 主任研究員 2010 : Tokyo Metropolitan Organization for Medical Research, 研究員 2008 – 2010 : Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 … More
Review Section/Research Field	Principal Investigator Experimental pathology / Urology / Obstetrics and gynecology Except Principal Investigator Human pathology / 動物発生・生理学 / Urology
Keywords	Principal Investigator 癌抑制遺伝子 / 大腸癌 / サブトラクション / 微小核融合法 / ホモロジー検索 / ノーザンブロット / 生殖細胞 / リバータント細胞 / W / スクリーニング … More Except Principal Investigator 癌抑制遺伝子 / 大腸癌 / 家族性大腸腺腫症 / 大腸腺腫 / 染色体移入 / p53遺伝子 / PCR-SSCP / 多段階発癌 / APC遺伝子 / RFLP / CFU-E / 対立遺伝子欠失 / DNA診断 / BFU-E / Colorectal Adenomas / 脾臓 / 転写制御 / 遺伝性非腺腫症大腸癌 / hemoglobin / Loss of Heterozygosity / CD44アイソフォーム / ハムスター / 遺伝子発現 / conditioned medium / c-KIt / 骨髄細胞培養液 / DNA不安定性 / DNA Diagnosis / 突然変異 / PCRーSSCP / c-Kit / 精原細胞 / K-ras mutation / セルトリ細胞 / 遺伝性大腸腫瘍 / 細胞分化 / 骨髄細胞 / 脾細胞培養液 / HNPCC / 精巣 / 転移 / Tumor Suppressor Genes / 遺伝性非腺腫性大腸癌 / spleen / AP遺伝子 / ヘモグロビン / ミスマッチ修復遺伝子 / 大腸腫瘍 / DCC遺伝子 / 遺伝性癌 / ヘテロ接合性消失 / 赤芽性前駆細胞 / 24p3 / bone marrow / inhibitor of erythropoiesis / Colorectal Carcinomas / 赤芽性分化抑制因子 / TGFβRII / マイクロサテライトDNA Less

精巣腫瘍における生殖幹細胞発現遺伝子ＤＤＸ１の個体での機能解析Principal Investigator
- Principal Investigator
  
  田中貴代子
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Functional analysis of DDX1 in testicular germ cell tumorsPrincipal Investigator
- Principal Investigator
  
  TANAKA Kiyoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Functional analysis and application of cancer treatment of unknown gene express in spermatogonial stem cells and cancer cellsPrincipal Investigator
- Principal Investigator
  
  TANAKA Kiyoko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
精巣の分化成熟を支配する精原細胞因子の解明
- Principal Investigator
  
  HARA Takahiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Isolation of genes involved in carcinogenesis of spermat ogonial stem cellsPrincipal Investigator
- Principal Investigator
  
  TANAKA Kiyoko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Organization For Medical Research The Tokyo Metropolitan Institute of Medical Science
A Role for ch1 in colorectal carcinomaPrincipal Investigator
- Principal Investigator
  
  TANAKA Kiyoko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan institute of Medical Science
1番染色体短腕36領域の大腸癌抑制遺伝子の単離と機能解析Principal Investigator
- Principal Investigator
  
  田中貴代子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
遺伝性大腸腫瘍の発生、進展に関与する遺伝子の解析
- Principal Investigator
  
  宮木美知子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
CD44バリアントの発現と大腸多段階発癌との関連
- Principal Investigator
  
  宮木美知子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
8番染色体短腕上の大腸癌の進展を抑制する遺伝子の検索Principal Investigator
- Principal Investigator
  
  田中貴代子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
正常8番染色体移入細胞を用いた大腸癌の進展に関与する癌抑制遺伝子の検索Principal Investigator
- Principal Investigator
  
  田中貴代子
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
マイクロサテライトおよびテロメアDNAによる大腸癌のDNA診断
- Principal Investigator
  
  宮木美知子
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
大腸癌の進行に伴うがん遺伝子、抑制遺伝子の変化
- Principal Investigator
  
  宮木美知子
- Project Period (FY)
  1993 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
正常1番染色体移入細胞を用いた大腸癌抑制遺伝子の検索Principal Investigator
- Principal Investigator
  
  田中貴代子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
大腸癌の進行に伴うがん遺伝子・抑制遺伝子の変化
- Principal Investigator
  
  宮木美知子
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
一般集団とFAP患者の大腸腫瘍におけるAPC遺伝子変異の解析
- Principal Investigator
  
  宮木美知子
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
大腸癌の進行に伴うがん遺伝子、抑制遺伝子の変化
- Principal Investigator
  
  宮木美知子
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
遺伝性大腸がんの発がん機構の解明
- Principal Investigator
  
  湯浅保仁
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Medical and Dental University
Suppression of tumor phenotypes of human colon carcinoma cells by introduction of normal chromosomesPrincipal Investigator
- Principal Investigator
  
  TANAKA Kiyoko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
大腸腺腫の悪性転換に関連する癌抑制遺伝子の研究
- Principal Investigator
  
  MIYAKI Michiko
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
DNA Diagnosis of Colorectal Carcinomas
- Principal Investigator
  
  MIYAKI Michiko
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science.
大腸癌の癌抑制遺伝子に関する研究
- Principal Investigator
  
  宮木美知子
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Regulation of the differentiation of multipotent and erythroid stem cells
- Principal Investigator
  
  MORIOKA Kiyokazu
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  動物発生・生理学
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science

All 2013 2012 2011 2010 2009 2008 2006 2005 Other

All Journal Article Presentation

[Journal Article] Tumor suppressive function of PTPN23 in testicular germ cell tumors is lost upon overexpression of miR-142-3p2013
- Author(s)
  Kiyoko Tanaka
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume : - Pages : 23990-23999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592356, KAKENHI-PROJECT-24591415, KAKENHI-PROJECT-25462495
[Journal Article] DDX1 (DEAD (Asp-Glu-Ala-Asp) box poly-peptide 1)2011
- Author(s)
  Takahiko Hara, Kiyoko Tanaka
- Journal Title
  
  Atlas Genet Cytogenet Oncol Haematol
  
  Volume : 15 Pages : 259-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592356
[Journal Article] A novel role for the intraflagellar transport protein CMG-1 in regulating the transcription of cyclin-D2, E-cadherin, and integrin-alpha family genes in mouse spermatocyte-derived cells2010
- Author(s)
  Ohbayashi, Tanaka, et al.
- Journal Title
  
  Genes to Cells (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591872
[Journal Article] Norvel role for the intraflagellar transport protein CMG-1 in regulating the transcription of cyclin-D2, E-cadherin and integrin alpha family genes in mouse spermatocyte-derived cells2010
- Author(s)
  K.Ohbayashi, K.Tanaka, K.Kitajima, K.Tamuta, T.Hara
- Journal Title
  
  Genes to Cells 15
  
  Pages : 699-710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591872
[Journal Article] DDX1[DEAD(Asp-Glu-Ala-Asp)box polypeptide 1]2010
- Author(s)
  T.Hara, K.Tanaka
- Journal Title
  
  Atlas Genet.Cytogenet.Oncol.Haematol.
- Data Source
  KAKENHI-PROJECT-20591872
[Journal Article] Novel role for the intraflagellar transport protein CMG-1 in regulating the transcription of cyclin D2, E-cadherin and integrin alpha family genes in mouse spermtocyte-derived cells.2010
- Author(s)
  Ohbayashi, K., Tanaka, K., et al
- Journal Title
  
  Genes to Cells
  
  Volume : 15 Pages : 699-710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591872
[Journal Article] DDX1 is required for the testicular tumorigenesis in part by transcriptional activation of 12p stem cell genes2009
- Author(s)
  Tanaka, et al.
- Journal Title
  
  oncogene 28
  
  Pages : 2142-2151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591872
[Journal Article] DDX1 is required for the testicular tumorigenesis in part by transcriptional activation of 12p stem cell genes.2009
- Author(s)
  K.Tanaka, S.Okamoto, Y.Ishikawa, H.Tamura, T.Hara
- Journal Title
  
  Oncogene 28
  
  Pages : 2142-2151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591872
[Journal Article] Spermatogonial cell-mediated activation of an IκBζ-independent NF-κB pathway in Sertoli cells induces transcription of the lipocalin-2 gene.2006
- Author(s)
  Fujino, R., Tanaka, K.et al.
- Journal Title
  
  Molecular Endocrinology 20(4)
  
  Pages : 904-915
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591771
[Journal Article] Capillary morphogenesis gene (CMG)-1 is among the genes differentially expressed in mouse male germ line stem cells and embryonic stem cells.2006
- Author(s)
  Fujino, R., Tanaka, K.et al.
- Journal Title
  
  Molecular reproduction and development 73
  
  Pages : 955-966
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591771
[Journal Article] Capillary morphogenesis gene (CMG)-1 is among the genes differentially expressed in mouse male germ line stem cells and embryonic stem cells.2006
- Author(s)
  Fujino, R., Ishikawa, Y., Tanaka, K., Kanatsu-Shinohara, M., Tamura, K., Kogo, H., Shinohara, T., Hara, T.
- Journal Title
  
  Mol.Reprod.Dev. 73
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591771
[Journal Article] Spermatogonial cell-mediated activation of an I B-independent NF-B pathway in Sertoli cells induces transcription of the lipocalin-2 gene.2006
- Author(s)
  Fujino, R., Tanaka, K., Morimatsu, M., Tamura, K., Kogo, H., Hara, T.
- Journal Title
  
  Mol.Endocrinol. 20(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591771
[Journal Article] Capillary morphogenesis gene (CMG)-1 is among the genes differentially expressed in mouse male germ line stem cells and embryonic stem cells.2006
- Author(s)
  R.Fujino, Y.Ishikawa, K.Tanaka, M.Shinohara, K.Tamura, H.Kogo, T.Shinohara, T.Hara
- Journal Title
  
  Molecular Reproduction and Development. (In press)
- Data Source
  KAKENHI-PROJECT-17591771
[Journal Article] Spermatogonial cell-mediated activation of an IkBz-independent NF-kB pathway in Sertoli cells induces transcription of the Lipocalin-2 gene.2006
- Author(s)
  Fujino, R., Tanaka, K., Morimatsu, M., Tamura, K., Kogo, H., Hara T.
- Journal Title
  
  Molecular Endocrinology 20
  
  Pages : 904-915
- Data Source
  KAKENHI-PROJECT-17591771
[Journal Article] Runx1 promotes angiogenesis by downregulation of insulin-like growth factor binding protein-3.2005
- Author(s)
  K.Iwatsuki, K.Tanaka et al.
- Journal Title
  
  Oncogene 24
  
  Pages : 1129-1137
- Data Source
  KAKENHI-PROJECT-14657412
[Journal Article] DDX1[DEAD(Asp-Glu-Ala-Asp) box poly peptide.
- Author(s)
  T.Hara, K.Tanaka
- Journal Title
  
  Atlas Genet.Cytogenet.Oncol.Haematol.
- URL
  http://AtlasGeneticsOncology.org/Genes/DDX1ID40283ch2p24.html
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] miR-142-3p is a potential prognostic biomarker for testicular germ cell tumors2012
- Author(s)
  Kiyoko Tanaka
- Organizer
  World Cancer Congress
- Place of Presentation
  montreal, CANADA
- Data Source
  KAKENHI-PROJECT-23592356
[Presentation] Tumor suppressor function of PTPN23 in testicular germ cell tumors2012
- Author(s)
  Kiyoko Tanaka
- Organizer
  71st Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23592356
[Presentation] Identification of a candidate tumor suppressor gene, PTPN23, in testicular germ cell tumor.2010
- Author(s)
  K.Tanaka, T.Hara
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] Identification of a candidate tumor suppressor gene, PTPN23, in testicular germ cell tumor2010
- Author(s)
  田中貴代子
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] DDX1 is required for the testicular tumorigenesis in part by transcriptional activation of 12p stem cell genes.2009
- Author(s)
  K.Tanaka, T.Hara
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] DDX1 is required for the testicular tumorigenesis in part by transcriptional activation of 12p stem cell genes2009
- Author(s)
  田中貴代子
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] overexpression of DDX1 promotes germ cell tumorigenesis.2008
- Author(s)
  K.Tanaka, T.Hara
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] 精巣腫瘍形成におけるDDX1の役割2008
- Author(s)
  田中貴代子、原孝彦
- Organizer
  第6回幹細胞シンポジウム
- Place of Presentation
  東京学術総合センター
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] overexpression of DDX1 promotes germ cell tumorigenesis2008
- Author(s)
  田中貴代子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] CMG1は精母細胞のcyclin D2及び接着関連遺伝子の転写を制御する2008
- Author(s)
  原孝彦、田中貴代子
- Organizer
  第6回幹細胞シンポジウム
- Place of Presentation
  東京学術総合センター
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20591872
[Presentation] 精巣腫瘍形成におけるDDX1の役割2008
- Author(s)
  田中貴代子
- Organizer
  第6回幹細胞シンポジウム
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20591872

1. MIYAKI Michiko (20085624)

# of Collaborated Projects : 10results

# of Collaborated Products : 0results
2. YANOSHITA Rei (00224915)

# of Collaborated Projects : 9results

# of Collaborated Products : 0results
3. 関まどか (80226638)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
4. 岡本美恵子 (80152354)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
5. 村岡正敏 (30260334)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. HARA Takahiko (80280949)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. MORIOKA Kiyokazu (10124497)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. 湯浅保仁 (80111558)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 堀井明 (40249983)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 馬場正三 (40107818)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 武藤徹一郎 (20110695)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 宇都宮謙二 (70013901)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. 小西元子

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. KITAJIMA Kenji

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
15. 近藤慶一

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

TANAKA Kiyoko 田中 貴代子

Research Projects

Research Products

Co-Researchers

精巣腫瘍における生殖幹細胞発現遺伝子ＤＤＸ１の個体での機能解析Principal Investigator

Principal Investigator

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Functional analysis of DDX1 in testicular germ cell tumorsPrincipal Investigator

Principal Investigator

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Functional analysis and application of cancer treatment of unknown gene express in spermatogonial stem cells and cancer cellsPrincipal Investigator

Principal Investigator

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Principal Investigator

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Isolation of genes involved in carcinogenesis of spermat ogonial stem cellsPrincipal Investigator

Principal Investigator

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A Role for ch1 in colorectal carcinomaPrincipal Investigator

Principal Investigator

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1番染色体短腕36領域の大腸癌抑制遺伝子の単離と機能解析Principal Investigator

Principal Investigator

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8番染色体短腕上の大腸癌の進展を抑制する遺伝子の検索Principal Investigator

Principal Investigator

Project Period (FY)

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正常8番染色体移入細胞を用いた大腸癌の進展に関与する癌抑制遺伝子の検索Principal Investigator

Principal Investigator

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Principal Investigator

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正常1番染色体移入細胞を用いた大腸癌抑制遺伝子の検索Principal Investigator

Principal Investigator

Project Period (FY)

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TANAKA Kiyoko 田中貴代子