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SAKATA Youichi  坂田 洋一

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坂田 洋一  サカタ ヨウイチ

SAKATA Yoichi  坂田 洋一

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Researcher Number 40129028
Other IDs
External Links
Affiliation (Current) 2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help 2009 – 2011: 自治医科大学, 医学部, 教授
2001 – 2006: Jichi Medical School, Cell and molecular medicine, Professor, 医学部, 教授
2002: 自治医科大学, Jichi Medical School Heamatology, Associate Professor
2001: 自治医科大学, 血液研究部門, 助教授
1988 – 2000: Jichi Medical School, 医学部, 助教授 … More
1999: 自治医科大学, 血液研究部門, 助教授
1999: Jichii University School of Medicine, Thoroloil Haemolais, Assistant Professor, 血液研究部門止血血栓, 助教授
1989 – 1990: 自治医科大学, 医学部, 講師
1988: 自治医大, 医学部, 講師
1988: 自治医科大学, 医学部・講師, 助教授に昇任
1986 – 1987: 自治医科大学, 医学部, 講師
1986: 自治医大, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Hematology
Except Principal Investigator
General surgery / Hematology / Hematology / Circulatory organs internal medicine / Gastroenterology / Otorhinolaryngology
Keywords
Principal Investigator
プラスミノゲン / プラスミン / 血管壁内皮細胞 / fibrin / プラスミノゲンアクチベータインヒビタ / アンギオスタチン / セレクチン / α_2プラスミンインヒビタ / plasminogen activator inhibitor / plasminogen activator … More / endothelial cells / プラスミノゲンアクチベータ / vitronectin / vitronection / アラスミノゲンアリチベータインヒビタ / plasminogen-deficient mice / Plasmin / granulocyte-derived elastase / Plasminogen activator inhibitor-1 / フィブリノゲン分解産物 / 白血球エラスターゼ / フィブリン分解産物 / プラスミノゲンノックアウトマウス / フィブリン / 白血球由来エラスターゼ / プラスミノゲンアクチベータインヒビタ1 / selectin / factor XIII / angiostatin / alpha2-plasmin inhibitor / plasminogen / 組織修復 / 細胞移動 / 架橋結合 / 血管内皮細胞 / α2プラスミンインヒビタ / 細胞遊走 / XIII因子 / α2-プラスミンインヒビタ / 組織型プラスミノゲンアクチベータ / 血栓溶解 / 癌転移 / 血管新生 / 組織線溶 / シアリルルイスX構造 / 基質特異性 / スタフイロキナーゼ / O結合型糖鎖 / 糖鎖構造 / N-methyl-deoxynojirimycin / alpha2-プラスミンインヒビタ / 血小板と線溶 / ビトロネクチン / ウロキナーゼ型プラスミノゲンアクチベータ / プラスミノゲンアクチベータインヒビター1 / CMK細胞 / 血小板α顆粒 / 骨髄巨核球 / プラスミノゲンアクチベ-タインヒビタ-1 … More
Except Principal Investigator
血管内皮細胞 / フィブリノゲン / 血栓塞栓症 / hereditary dysfibrinogen / 遺伝性異常フィブリノゲン / 血栓症 / 異常フィブリノゲン / 血栓 / 遺伝子治療 / endothelial cell / PAI-1 / thrombosis / 電顕学的分析 / フィブリノゲン異常症 / 遺伝子解析 / モノクロナル抗体 / プロテインC / 分子異常症 / 血管新生 / アンチトロンビンIII / 免疫寛容 / 第VIII因子欠損マウス / 血友病A / VEGF / viral vector / Factor VIII / Hemophilia A / db / NOD / gene therapy / Gene therapy / fibrin ultra-structure / bleeding tendency / fibrinogen / フィブリンの超微細構造 / 血栓性素因 / 余剰糖鎖 / フィブリン超微細構造 / 出血傾向 / アンギオスタチン / 深部静脈血栓症 / gene targeting / plasminogen activator inhibitor 2 / fibrinolysis / thromboembolism / フィブリンの電顕像 / フィブリン / 接着分子 / abnormal fibrinogen / 出血性素因 / インテグリン / 細胞接着 / フィブリン重合反応 / Thrombus formation / 血栓形成 / plasminogen activator inhibitor / 血管壁弛緩因子 / 血管壁収縮因子 / トロンボモジュリン / 線維素溶解現象 / 平滑筋細胞 / Thromboembolic disease / Monoclonal antibodies / Protein C / Abnormal fibrinogen / Molecular abnormality / 血液凝固制御機構 / トロンビン-アンチトロンビンIII複合体 / abnormal protein C / protein C / abnormal antithrombin III / antithrombin III / Surgical thromboembolic diseases / プロテインC分子異常症 / プロテインC欠損症 / アンチトロンビン【III】欠損症 / アンチトロンビン【III】 / 血栓塞栓性疾患 / プロテインC異常症 / 異常アンチトロンビンIII / 外科的血栓塞栓疾患 / high resolution image system / regulatory T cells / thymus / immune tolerance / inhibitor / factor VIII / hemophilia A / 樹状細胞 / 抗第VIII因子インヒビター / SIVベクター / 胸腺 / 細胞療法 / 制御性T細胞 / 胸腺組織 / インヒビター / knockout mice / Neonate / Immune tolerance / ウイルスベクター / 新生児 / Prostacyclin / Angiopoietin 1 / Vascular endothelial growth factor / db mice / SCID mice / Adipocyte / Hematopoietic stem cell / SIV virus vector / 肝細胞 / dbマウス / SCIDマウス / 脂肪細胞 / 造血幹細胞 / SIVウイルスベクター / 血液凝固第VIII因子 / 血友病 / liver endothelial cells / Angiostain / 腫瘍血管 / 肝臓内皮細胞 / plasminogen activator inhibitor 1 / adeno-associated virus vector / thrombomodulin / Thrombosis / AAV vector / Endothelial cell / Thorombosis / Thrombomodulin / Adeno-associated virus vector / gene analysis / fibrin nets / extra carbohydrate / fibrinogen structure / 停止コドンの消失 / 糖付加構造 / 余剩糖鎖 / フィブリン網 / フィブリノゲンの構造 / 遺伝性フィブリノゲン / anti-angiogenesis / monoclonal antibody / structural alteration / 抗フィブリノゲン・モノクロナル抗体 / 点変異 / 抗血管新生 / 構造異常 / coagulation & fibrinolysis / plasminogen / hepatocellular carcinoma / angiostatin / 血液凝固線溶系 / プラスミノーゲン / 肝細胞癌 / electron microscopic analysis of fibrin / plasmin / intermolecular crosslink / pulmonary embolism / deep veinthrombosis / extra oligosaccharide / fibrin gels / XIIIa因子による分子間架橋 / フィブリンの電顕学的分析 / 線溶酵素プラスミン / Xllla因子による分子間架橋 / 肺塞栓症 / 余剰糖鎖付加 / embryonic stem cell / Plasminogen activator inhibitor / cross-linking / extra glycosylation / ultrastructure of fibrin / dysfibrinogen / 架橋結合 / 余剰糖付加 / kininogen / beta1-integrin / adhesion molecule / fibrin / electron microscopy / RGD配列 / 接着分子受容体 / 一過性虚血発作 / フィブリン重合 / 分子異常 / 腫瘍の転移 / キニノゲン / β1インテグリン / 線維芽細胞 / Adhesion molecule / Cell attachment / Monoclonal antibody / Calcium-dependent structure / Crosslinking / Fibrin polymerization / Hereditary dysfibrinogen / Fibrinogen / 接着分子のレセプター / 創傷治癒不全 / 出血 / 遺伝性フィブリノゲン異常症 / モノクローナル抗体 / モノクロナール抗体 / カルシウム依存性構造 / 架橋形成 / integrin / high-molecular-weight kininogen / cell adhesion / abnormal factor IX / hemophilia B / fibrin polymerization / hereditary dysfibrinogenemia / フィブリン重合障害 / グリオーマ細胞 / 異常第IV因子 / 高分子キニノゲン / 異常第IX因子 / 血友病B / Regulation of thrombus formation / Vascular endothelial cells, / Thromboembolic disease, / Monoclonal antibodies, / Protein C, / Abnormal fibrinogen, / Molecular abnormality, / アミノ酸置換 / 異常プロテインC / 遺伝性分子異常症 / 血栓形成抑制機構 / 血管平滑筋 / エンドセリン / 増殖因子 / 線維素溶解 / 凝固 / 線溶系遺伝子 / 感音難聴 / 耳科学 / vitronectin / plasminogen activator / ype 1 plasminogen activator inhibitor / phorbol ester / glycoprotein IIb / 血小板 / 骨髄巨核芽球 Less
  • Research Projects

    (34 results)
  • Co-Researchers

    (28 People)
  •  Hearing functional analysis of fibrinolytic components gene mutant mice

    • Principal Investigator
      ISHIKAWA Kotaro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Jichi Medical University
  •  Induction of factor VIII specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Induction of Immune Tolerance by Neonatal Intravenous Injection of Human Factor VIII in Murine Hemophilia A

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      JICFII MEDICAL SCHOOL
  •  The study of tumor vessel growth inhibiton Angiostatin, new mechanism of action and clinical application

    • Principal Investigator
      MITSUI Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Regulation of granulocyte-derived elastase-dependent fibrinolysisPrincipal Investigator

    • Principal Investigator
      SAKATA Yoichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Gene therapy for hemophilia A with simian immunodeficiency virus agmTYO1-based vectors carrying human factor VIII gene.

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Regulation of endothelial cell function by transgene expression and development of gene therapy for vascular diseases

    • Principal Investigator
      MIMURO Jun
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Jichi Medical School
  •  Regulation of endothelial cell functions by gene transfer using viral vectors

    • Principal Investigator
      MIMURO Jun
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Jichi Medical School
  •  STUDIES ON THE PATHOPHYSIOLOGY OF THROMBOEMBOLIC DISEASES WITH SPECIAL REFERENCE TO THE UNDERLYING IMPAIRED BLOOD COAGULATION AND ITS REGULATION

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  Molecular basis for the fibrinogen structure and functions-Analysis Of hereditary dysfibrinogens and their application to the study

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  Molecular basis for the fibrinogen structure and functions - Analysls of hereditary dysfibrinogens and their application to the study

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  Characterization of the anti-angiogenic factors in hepatocellular carcinoma10301102

    • Principal Investigator
      MAEKAWA Hisato
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Molecular basis for the fibrinogen structure and functions-Analysis of hereditary dysfibrinogens and their application to the study

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School, School of Medicine
  •  Analysis of the molecular mechanism in regulation of cell migration by alpha2-plasmin inhibitorPrincipal Investigator

    • Principal Investigator
      SAKATA Yoichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School, School of Medicine
  •  Gene targeting of plasminogen activator inhibitor 2

    • Principal Investigator
      MIMURO Jun
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School, School of Medicine
  •  血管新生抑制物質-アンギオスタンチンの機能部位の分子生物学的解析Principal Investigator

    • Principal Investigator
      坂田 洋一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Etiology and pathophysiology of thrombosis : A molecular biological aproach to elucidate disturbed mechanisms of blood coagulation and its inhibition.

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School, School of Medicine
  •  組織における線溶反応の動的制御機構の分子生物学的解析Principal Investigator

    • Principal Investigator
      坂田 洋一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  スタフィロキナーゼの血栓溶解活性発現機作の分子生物学的解析Principal Investigator

    • Principal Investigator
      坂田 洋一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Etiology and pathophysiology of thrombosis : A molecular biological aproach to elucidate disturbed mechanisms of blood coagulation and its inhibition.

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  線溶因子の細胞内代謝、及び生物活性に果たす糖鎖の役割の分子生物学的解析Principal Investigator

    • Principal Investigator
      坂田 洋一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jichi Medical University
  •  血小板内プラスミノゲンアクチベータインヒビタの産生部位と活性化機序の解明Principal Investigator

    • Principal Investigator
      坂田 洋一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  プラスミノゲンアクチベータインヒビタ及びビトロネクチンの構造と機能に関する研究

    • Principal Investigator
      三室 淳
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Studies on the etiology and pathophysiology of thrombosis : molecular biological approaches to the perturbed blood coagulation and its regulation.

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  プラスミノゲンアクチベ-タインヒビタの放出機序の分子、遺伝子レベルの解析Principal Investigator

    • Principal Investigator
      坂田 洋一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  血管内皮細胞由来の血栓調節因子の機能解析

    • Principal Investigator
      居石 克夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  骨髄巨核芽球,及び,骨髄巨核球における凝固線溶因子の遺伝子制御

    • Principal Investigator
      MIMURO Jun
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Pathogenesis and pathophysiology of thromboembolic diseases - analysis of the mechanisms of blood coagulation and its regulation at the molecular and gene levels.

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  血管内皮細胞由来の血栓調節因子の機能解析

    • Principal Investigator
      居石 克夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  血管内皮細胞由来の血栓調節因子の機能解析

    • Principal Investigator
      居石 克夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  Studies on the pathogenesis and pathophysiology of thromboembolisms in the field of surgery. Development of novel techniques for analyzing the regulatory systems of blood coagulation.

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  Analysis of the mechanism of endothelial cell -dependent activation of plasminogen activator inhibitorPrincipal Investigator

    • Principal Investigator
      SAKATA Yoichi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  人血管壁内皮細胞でのプラスミノゲン活性化酵素のインヒビタの産生と放出機序の解明Principal Investigator

    • Principal Investigator
      坂田 洋一
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Studies on pathophysiology of surgical thromboembolic diseases with special reference to impaired regulation of blood coagulation.

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  • 1.  MIMURO Jun (10221607)
    # of Collaborated Projects: 23 results
    # of Collaborated Products: 0 results
  • 2.  MATSUDA Michio (50048980)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 3.  MADOIWA Seiji (70296119)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 4.  SUGO Teruko (60183844)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 5.  ASAKURA Shinji (70245033)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  TERUKINA Shigeharu (80146159)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  MAEKAWA Hisato (10221574)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  居石 克夫 (70108710)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  丸山 征郎 (20082282)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  広瀬 茂久 (10134199)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  高久 史麿 (40048955)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  WEISEL John W.
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  KOBAYASHI Fiji (00245044)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  MITSUI Hiroshi (30239280)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  MARUYAMA Toshiyuki (30219571)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  MURAMATSU Shin-ichi (10239543)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  MOROI Masaaki (00049074)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  YOSHIDA Nobuhiko (10049083)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  MURAYAMA Hideki (70146166)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  ISHIKAWA Kotaro (60347987)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  ISHIMURA Keiichi (00010471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  MAEKAWA Hisato (10301102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  TSUKAMOTO Kazuhisa (20251233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  MIZUKAMI Hiroaki (20311938)
    # of Collaborated Projects: 1 results
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  • 25.  室田 誠逸 (50072989)
    # of Collaborated Projects: 1 results
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  • 26.  中村 謙一 (10448855)
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    # of Collaborated Products: 0 results
  • 27.  MOSESSON Michael W.
    # of Collaborated Projects: 1 results
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  • 28.  MOSESSON Mic
    # of Collaborated Projects: 1 results
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