SONE Saburo 曽根三郎

Researcher Number	40145024
Other IDs
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Affiliation (based on the past Project Information) *help	2012: 徳島大学, ヘルスバイオサイエンス研究部, 客員教授 2012: 徳島大学, 大学院・ヘスルバイオサイエンス研究部, 客員教授 2011 – 2012: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 客員教授 2006 – 2010: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 2005: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 … More 2004: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 教授 1994 – 2003: 徳島大学, 医学部, 教授 1992 – 1993: 徳島大学, 医学部, 助教授 1987 – 1992: 徳島大学, 医学部附属病院, 講師 1991: 徳島大学, 医学部, 講師 1989 – 1990: Tokushima Univ. Sch. of Med., Lecturer, 医学部・附属病院, 講師 1986 – 1987: 徳島大学, 医学部, 講師 1986: Tokushima University School of Medicine, Lecturer, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator 内科学一般 / Biological Sciences / Respiratory organ internal medicine / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / General surgery / Science and Engineering / Clinical oncology / 物質生物化学 / 応用薬理学・医療系薬学 / General medical chemistry
Keywords	Principal Investigator 肺癌 / 免疫療法 / サイトカイン / 薬剤耐性 / 血管新生 / 肺胞マクロファージ / マクロファージ / 腫瘍壊死因子 / MCP-1 / 多剤耐性 … More / P糖蛋白質 / ADCC / 免疫遺伝子治療 / 抗体治療 / PTHrP / VEGF / 癌性胸水 / 骨転移 / 多臓器転移 / 樹状細胞 / マイクロアレイ / TNF / IL-10 / IL-1ra / Lung cancer / MRK16 / CD13 / 肺がん / 転移 / 遺伝子治療 / SCIDマウス / 転移モデル / ガンクリオシドGM2 / モノクローナル抗体 / NK細胞 / VEGF受容体 / 血管標的薬 / 分子標的治療 / EGF受容体 / MMP / 臓器微小環境 / cDNAマイクロアレイ / 浸潤 / KAI1 / CD82 / ガングリオシド / 抗体療法 / 破骨細胞 / 可溶性VEGF受容体 / EGFR阻害薬 / 肝細胞増殖因子 / 抗HM1.24抗原 / HGF / マルチキナーゼ阻害薬 / 胸膜中皮腫 / organotropism / 抗PTHrP抗体 / ビスフォスフォネート / HM1.24抗原 / 耐性 / ゲフィチニブ / プロテオーム解析 / 脳転移 / 蛍光気管支鏡 / MYO18B / Src / CD9 / 非閉塞性肺疾患 / 悪性胸膜中皮腫 / 同所移植モデル / 膜結合型TNF-α / 細胞障害 / 膜型腫瘍壊死因子 / インターロイキン-4 / 活性酸素 / マクロファ-ジ / 抗腫瘍活性 / インタ-ロイキン・4 / membrane TNF-alpha, alveolar macrophages, cytotoxicity, lung cancer / パラクライン / IL-6 / MCAF / Cytokine / Paracrine / Macrophage / single chain antibody fragment / P糖蛋白 / single chan抗体 / ケモカイン / MRK-16 / Multi-drug resistance / P-glycoprotein / single chain antibody / 放射線肺臓炎 / Aminopetidase N / Bestatin / Aminopeptidase N / radiation pneumonitis / aminopeptidase N / macrophages / bestatin / ヒト単球 / 腫瘍細胞傷害因子 / モノャイン / Macrophages / Monocytes / Antitumor monokines / Human / 単球 / 肺胞マクロファ-ジ / モノセイン / IL-1 / 癌患者 / モノカイン / マクロファージモノカイン / インターロイキン1 / リポソーム / 細胞障害作用 / Monocyte / Alveolar macrophage / Monokine / Interleukin 1 / tumor necrosis factor … More Except Principal Investigator GALA / 抗腫瘍性サイトカイン / 多剤耐性(MDR)腫瘍 / 多剤耐性遺伝子(MDR1) / MDR1mRNA発現 / トランスフェリン / エンドサイトーシス / 細胞内動態制御 / マクロファージ活性化因子 / ヒトT細胞ハイブリドーマ / 単クローン性抗体 / 細胞障害作用 / リポソ-ム / マクロファ-ジ / 細胞内挙動 / 腫瘍壊死因子 / Membrane action / Antitumor cytokine / Liposome / Macrophage / 膜融合 / 肺線維芽細胞 / IL-4 / 線維芽細胞 / リポソーム / ヒトマクロファージ / 単球 / interleukin 2 / 腫瘍細胞障害 / 造血因子 / サイトセイン / 肺転移 / リンパ浮腫 / リンパ球動注 / 新鮮リンパ球 / 培養リンパ球 / 二次元電気泳動法 / 蛋白分解 / 多剤耐性腫瘍 / P糖蛋白(Pーglycoprotein;Pーgp) / 抗Pーgp抗体MRK16 / 抗Pーgp抗体C219 / 多剤耐性遺伝子(mdr1) / mdr1mRNA発現 / ヒトマウスキメラ抗体 / magneticーaffinity cell sorring(MACS)法 / P糖蛋白(P-glycoprotain;P-gp) / 抗P-gp抗体(MRK16,C219,U1C) / ヒト・マウスキメラ抗体 / 免疫磁気ビーズ(MACS)法 / rhodamino123effluxtest / P糖蛋白(P-gp) / 抗P-gp抗体 / 血液脳関門 / MDR癌の免疫療法 / cyclosporin A(CsA)誘導体 / オクタアルギニン / ステアリルオクタアルギニン / 原子間顕微鏡 / パッケージング / 遺伝子ベクター / 分子シンクロナイゼーション / 分子標的治療 / thymidine phosphorylase / 解糖経路 / ペントースリン酸経路 / IL-8 / TP / NADPH / NFkB / NADPH oxidase / ROS / pentose phosphate pathway / チミジンホスホリラーゼ / 解糖系 / ガンマインタフェロン / リポゾーム / 遺伝子クローニング / ヒトマクロファージハイブリドーマ / ガンマインターフェロン / リボゾーム / 膜作用 / ホスファチジルセリン / リポソ-ム結合型サイトカイン / リポソ-ム膜結合型サイトカイン / インタ-ロイキンー4 / インタ-フェロン / 膜脂質組成 / Cytotoxic action / Phosphatidylserine / Intracellular behavior / Liposome-bound cytokine / 腫瘍細胞 / 顕微蛍光測光法 / 顕微蛍光法 / Antitumor Cytokines / Tumor Cells / Cytotoxic Effect / Intracellular Behavior / Fluorescence Microphotometry / Membrane Fusion. / 肺線維症 / 細胞関連型IL-1(IL-1α) / プロスタグランデインE2 / サイクロオキシゲナーゼ / TNF / IL-1 / プロスタグランディンE_2 / 好中球遊走因子 / 1L-1α, / 肺胞マクロファージ / Pulmonary Fibrosis / Cell-associated IL-1 / Fibroblast / Prostaglandin E2 / Cyclooxygenase / 国際学術 / 海外派遣 / 癌 / 細胞社会学 / シグナル伝達 / 細胞周期 / 薬品設計 / 遺伝子治療 / ウイルス発癌 / 細胞接着 / 癌治療 / 化学発癌 / 情報交換 / ドラッグデザイン / 癌遺伝子治療 / 癌化学療法 / 細胞増殖 / International Scientific Research / Cancer / Information Exchange / Signal Transduction / Cell Cycle / Cell Adhesion / Drug Design / Gene Therapy / 線維化 / Th1様サイトカイン / Th2様サイトカイン / cyclooxygenase (COX) / COX2 / PGE2 / 単球・マクロファージ / cyclooxygenase(COX)1 / iuterleukin-1 / Prostaglaudin E_2 / Cyclooxygeuase 1 / Cyclooxygeuase 2 / pulmonary fibrosis / prostaglandin E2 / cyclooxygenase-2 / Th1 cell associated cytokine / Th2 cell associated cytokine / fibroblast / monocyte / macrophage / トランスフェリン修飾リポソーム / リサイクル / 耐性 / intracellular trafficking / transferrin liposomes / endocytosis / recycling / 抗腫瘍作用 / 膜損傷作用 / 膜間脂質分子交換 / クラスリン / 燐脂質移送蛋白質 / インターフェロン / Antitumor Action / Membrane fusion / Phospholipid exchange between Membranes / Clathrin / Phospholipid exchange protein Less

Investigation of the novel anti-angiogenesis therapy in an orthotopic implantation mouse model of human malignant pleural mesothelioma cellsPrincipal Investigator
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokushima
Molecular basis for thefunctions of thymidine phosphorylase and preclinical study of an inhibitor of thymidine phosphorylase , TPI
- Principal Investigator
  
  AKIYAMA Shin-ichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  The University of Tokushima
Development of molecular targeted therapy for lung cancer metastasis considering characteristics of organ microenvironmentPrincipal Investigator
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Studies on new molecular therapeutic approach for radiation pneumonitisPrincipal Investigator
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokushima
選択的抗癌システムを目指した細胞内動態の分子シンクロナイゼーション
- Principal Investigator
  
  HIDEYOSHI Harashima
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Studies on the generation and application of fusion protein of single chain antibody for P-glycoprotein and chemokinePrincipal Investigator
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokushima
肺がんの転移・血管新生分子を標的とした生物学的制御法開発Principal Investigator
- Principal Investigator
  
  曽根三郎
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Intracellular control of transferrin-modified liposomes with Cholesteryl GALA for optimum drug delivery system
- Principal Investigator
  
  HIDEYOSHI Harashima
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  HOKKAIDO UNIVERSITY
肺がんの薬剤耐性と転移因子を分子標的とした免疫遺伝子治療Principal Investigator
- Principal Investigator
  
  曽根三郎
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokushima
Cytokine production by human lung cancer and its paracrine regulationPrincipal Investigator
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokushima
Information Exchange on Cancer Research with North American
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The University of Tokyo
Investigation on the pathogenesis of pulmonary fibrosis
- Principal Investigator
  
  OGUSHI Fumitake
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tokushima
モノクロナール抗体遺伝子を用いた耐性癌の基礎的な診断と治療に関する研究
- Principal Investigator
  
  白川茂
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Mie University
モノクロトール抗体,遺伝子を用いた耐性癌の基礎的な診断と治療にする研究
- Principal Investigator
  
  白川茂
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Mie University
The roles of cytokines in pulmonary fibrosis
- Principal Investigator
  
  OGUSHI Fumitaka
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tokushima, School of Medicine
モノクロナ-ル抗体,遺伝子を用いた耐性癌の基礎的な診断と治療に関する研究
- Principal Investigator
  
  白川茂
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Mie University
MEMBRANE-FORM TUMOR NECROSIS FACTOR : ANALYSIS AND CLINICAL APPLECATION OF ACTIVATED ALVEOLAR MACROPHAGESPrincipal Investigator
- Principal Investigator
  
  SONE Saburo, NII Akihiko
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  UNIVERSITY OF TOKUSHIMA, SCHOOL OF MAEDICINE
Studies on the Molecular Mechanisms of Cytotoxic Action of Antitumor Cytokines Using Liposome Systems
- Principal Investigator
  
  YOSHIMURA Tetsuro
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Tokushima
ヒトマクロファージによる抗腫瘍性エフェクター誘導調節機構の解析
- Principal Investigator
  
  小倉剛
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokushima
慢性リンパ浮腫に対するリンパ球動注療法の研究
- Principal Investigator
  
  加藤逸夫
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokushima
Studies on the Mechanism of Cytotoxic Action of Antitumor Cytokines Using Liposomal Membrane Systems
- Principal Investigator
  
  YOSHIMURA Tetsuro
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  The University of Tokushima
Antitumor activity of monocyte-macrophages and its potentiation in cancer patientsPrincipal Investigator
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Tokushima University School of Medicine
マクロファージ活性化因子とその制癌への応用に関する実験的研究
- Principal Investigator
  
  大沢利昭
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Studies on the Mechanisms of Action of Antitumor and Membrane-Active Proteins Using Artificial Membranes (Liposomes)
- Principal Investigator
  
  YOSHIMURA Tetsuro
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
マクロファージ活性化因子とその制癌への応用に関する実験的研究
- Principal Investigator
  
  大沢利昭
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Characterization and function of antitumor monokines produced by human monocyte-macrophagesPrincipal Investigator
- Principal Investigator
  
  SONE SABURO
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Tokushima University School of Medicine

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All Journal Article Presentation Book

[Book] 学研メディカル秀潤社、がん転移:臨床と研究の羅針盤2010
- Author(s)
  曽根三郎
- Data Source
  KAKENHI-PROJECT-22390166
[Book] 今日の診断指針第6版2010
- Author(s)
  曽根三郎, 他
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22390166
[Book] がん転移(臨床と研究の羅針盤)2010
- Author(s)
  曽根三郎, 他
- Publisher
  (株)学研メディカル秀潤社
- Data Source
  KAKENHI-PROJECT-22390166
[Book] 今日の診断指針第6 版2010
- Author(s)
  曽根三郎
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22390166
[Book] 疾患と治療薬改訂第6版-医師・薬剤師の為のマニュアル2010
- Author(s)
  曽根三郎
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22390166
[Book] 疾患と治療薬改訂第6版(医師・薬剤師の為のマニュアル)2010
- Author(s)
  曽根三郎, 他
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22390166
[Book] がん分子標的治療研究実践マニュアル2009
- Author(s)
  曽根三郎, ら
- Total Pages
  329
- Publisher
  (株)金芳堂
- Data Source
  KAKENHI-PROJECT-17016051
[Book] がん分子標的治療研究実践マニュアル2009
- Author(s)
  曽根三郎, 他
- Total Pages
  329
- Publisher
  株式会社金芳堂
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Macrophage stimulating protein promotes liver metastases of small cell lung cancer cells by affecting the organ microenvironment.2013
- Author(s)
  Sato S, Hanibuchi M, Kuramoto T, Yamamori N, Goto H, Ogawa H, Mitsuhashi A, Van TT, Kakiuchi S, Akiyama SI, Nishioka Y, Sone S
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 30 Pages: 333-344
- DOI
  10.1007/s10585-012-9540-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-22501048, KAKENHI-PROJECT-24390210
[Journal Article] Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells.2012
- Author(s)
  Tabata S, Ikeda R, Yamamoto M, Furukawa T, Kuramoto T, Takeda Y, Yamada K, Haraguchi M, Nishioka Y, Sone S
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 28 Pages: 895-902
- DOI
  10.3892/or.2012.1887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-22501047, KAKENHI-PROJECT-22501048, KAKENHI-PROJECT-22510236, KAKENHI-PROJECT-22590287, KAKENHI-PROJECT-24390210
[Journal Article] Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer2012
- Author(s)
  Takeuchi S, Wang W, Li Q, Yamada T, Kita K, Donev IS, Nakamura T, Matsumoto K, Shimizu E, Nishioka Y, Sone S, Nakagawa T, Uenaka T, Yano
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 181 Pages: 1034-1043
- DOI
  10.1016/j.ajpath.2012.05.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390210, KAKENHI-PROJECT-24659403
[Journal Article] an inhibitor of Dll4-Notch signaling, suppresses liver metastasis of small cell lung cancer cells through the downregulation of the NF-kappa-B activity2012
- Author(s)
  Kuramoto T, Goto H, Mitsuhashi A, Tabata S, Ogawa H, Uehara H, Sijo A, Kakiuchi S, Maekawa, Yasutomo K, Hanibuchi M, Akiyama SI, Sone S, Nishioka Y
- Journal Title
  
  Molecullar Cancer Theraputics
  
  Volume: 11 Pages: 2578-2587
- DOI
  10.1158/1535-7163.mct-12-0640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679005, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-22501048, KAKENHI-PROJECT-24390210, KAKENHI-PROJECT-24590585
[Journal Article] 呼吸器疾患におけるトランスレーショナルリサーチ:現状と将来展望2012
- Author(s)
  西岡安彦, 曽根三郎
- Journal Title
  
  呼吸器内科
  
  Volume: 21 Pages: 483-484
- URL
  http://www.kahyo.com/item/KO201206-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166
[Journal Article] E7050, a Met kinase inhibitor, reverses three different mechanisms of hepatocyte growth factor-induced resistance to tyrosine kinase inhibitorsin EGFR mutant lung cancer cells2012
- Author(s)
  Wang W, Li Q, Takeuchi S, Yamada T, Koizumi H, Nakamura T, Matsumoto K, Mukaida N, Nishioka Y, Sone S, Uenaka T, Yano S
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 18 Pages: 1663-1671
- DOI
  10.1158/1078-0432.ccr-11-1171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390210
[Journal Article] Identification of genes potentially involved in bone metastasis by genome-wide gene expression profile analysis of non-small cell lung cancer in mice2012
- Author(s)
  Dat LT, Matsuo T, Yoshimaru T, Kakiuchi S, Goto H, Hanibuchi M, Kuramoto T, Nishioka Y, Sone S, Katagiri T
- Journal Title
  
  Int J Oncol.
  
  Volume: 40 Pages: 1455-1469
- DOI
  10.3892/ijo.2012.1348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-22700882, KAKENHI-PROJECT-24390210, KAKENHI-PUBLICLY-23134504
[Journal Article] SU6668, a multiple tyrosine kinase inhibitor, inhibits progression of human malignant pleural mesothelioma in an orthotopic model.2012
- Author(s)
  Van TT, Hanibuchi M, Goto H, Kuramoto T, Yukishige S, Kakiuchi S, Sato S, Sakaguchi S, Dat LT, Nishioka Y, Akiyama SI, Sone S, SU666
- Journal Title
  
  Respirology
  
  Volume: 17 Pages: 984-990
- DOI
  10.1111/j.1440-1843.2012.02193.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-22501048, KAKENHI-PROJECT-24390210
[Journal Article] Pleural mesothelioma instigates tumor associated fibroblasts to promote progression via malignant cytokine network2011
- Author(s)
  Li Q, Wang W, Yamada T, Matsumoto K, Bando Y, Uehara H, Nishioka Y, Sone S, Iwakiri S, Itoi K, Utsugi T, Yano S.
- Journal Title
  
  Am J Pathol
  
  Volume: 179 Pages: 1483-1493
- DOI
  10.1016/j.ajpath.2011.05.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23659434, KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-23790902
[Journal Article] Genetically engineered humanized anti-ganglioside GM2 antibody against multiple organ metastasis produced by GM2 expressing small cell lung cancer2011
- Author(s)
  Yamada T, Bando H, Takeuchi S, Kita K, Li Q, Wang W, Akinaga S, Nishioka Y, Sone S, Yano S.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 2157-2163
- DOI
  10.1111/j.1349-7006.2011.02093.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903
[Journal Article] ntiangiogenic therapies for malignant pleural mesothelioma2011
- Author(s)
  Yano S, Li Q, Wang W, Yamada T, Takeuchi S, Nakataki E, Ogino H, Goto H, Nishioka Y, Sone S
- Journal Title
  
  Front Biosci
  
  Volume: 16 Pages: 740-748
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21196199.
- Data Source
  KAKENHI-PROJECT-22390166
[Journal Article] E7080 suppresses hematogenous multiple organ metastases of lung cancer cells with nonmutated epidermal growth factor recepto2011
- Author(s)
  Ogino H, Hanibuchi M, Kakiuchi S, Trung Van The, Goto H, Ikuta K, Yamada T, Uehara H, Tsuruoka A, Uenaka T, Wang W, Li Q, Takeuchi S, Yano S, Nishioka Y, Sone S.
- Journal Title
  
  Mol Cancer The
  
  Volume: 10 Pages: 1218-1228
- DOI
  10.1158/1535-7163.mct-10-0707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903
[Journal Article] The therapeutic efficacy of S-1 against orthotopically implanted human pleural mesothelioma cells in severe combined immunodeficient mice2011
- Author(s)
  Van TT, Hanibuchi M, Kakiuchi S, Sato S, Kuramoto T, Goto H, Mitsuhashi A, Nishioka Y, Akiyama S, Sone S
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 68 Pages: 497-504
- DOI
  10.1007/s00280-010-1503-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-22501048
[Journal Article] Role of tyrosine kinase inhibitors in tumor immunology2011
- Author(s)
  Nishioka Y, Aono Y, Sone S
- Journal Title
  
  Immunotherapy
  
  Volume: 3 Pages: 107-116
- DOI
  10.2217/imt.10.79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166
[Journal Article] Gender difference in bone metastasis of human small cell lung cancer, SBC-5 cells in natural killer-cell depleted severe combined immunodeficient mice2010
- Author(s)
  Sakaguchi S, Goto H, Hanibuchi M, Otsuka S, Ogino H, Kakiuchi S, Uehara H, Yano S, Nishioka Y, Sone S
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 27 Pages: 351-359
- DOI
  10.1007/s10585-010-9333-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PROJECT-22390166
[Journal Article] Hepatocyte growth factor reduces susceptibility to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer.2010
- Author(s)
  Yamada T, Matsumoto K, Wang W, Li Q, Nishioka Y, Sekido Y, Sone S, Yano S.
- Journal Title
  
  Clin Cancer Res 16
  
  Pages: 174-183
- NAID
  120001939468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Intensification therapy with anti-parathyroid hormonerelated protein antibody plus zoledronic acid for bone metastases of small cell lung cancer cells in severe combined immunodeficient mice.2009
- Author(s)
  Yamada T, Muguruma H, Yano S, Ikuta K, Ogino H, Kakiuchi S, Hanibuchi M, Uehara H, Nishioka Y, Sone S.
- Journal Title
  
  Mol Cancer Ther 8
  
  Pages: 119-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] A Bone metastasis model with osteolytic and osteoblastic properties of human lung cancer ACC-LC-319/bone2 in natural killer cell-depleted severe combined immunodeficient mice.2009
- Author(s)
  Otsuka S, Hanibuchi M, Ikuta K, Yano S, Goto H, Ogino H, Yamada T, Kakiuchi S, Nishioka Y, Takahashi T, Sone S.
- Journal Title
  
  Oncol Res 17
  
  Pages: 581-591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Chimeric and humanized anti-HM1. 24 antibodies mediate antibody-dependent cellular cytotoxicity against lung cancer cells.2009
- Author(s)
  Wang W, Nishioka Y, Ozaki S, Jalili A, Verma VK, Hanibushi M, Abe S, Minakuchi K, Matsumoto T, Sone S.
- Journal Title
  
  Lung Cancer 63
  
  Pages: 23-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangiogenic cytokine production profiles.2009
- Author(s)
  Ikuta K, Yano S, Trung VT, Hanibuchi M, Goto H, Li Q, Wang W, Yamada T, Ogino H, Kakiuchi S, Uehara H, Sekido Y, Uenaka T, Nishioka Y, Sone S.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 7229-7237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property.2009
- Author(s)
  Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Rentsenh, B, Makino H, Ranjan P, Minakuchi K, Sone S.
- Journal Title
  
  J Immunol 183
  
  Pages: 8176-8185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Crosstalk to stromal fibroblasts induces resistance of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors2009
- Author(s)
  Wang W, Li Q, Yamada T, Matsumoto K, Matsumoto I, Oda M, Watanabe G, Kayano Y, Nishioka Y, Sone S, Yano S.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 6630-6638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] HM1. 24 (CD317) is a novel target against lung cancer for immunotherapy using anti-HM1. 24 antibody.2009
- Author(s)
  Wang W, Nishioka Y, Ozaki S, Jalili A, Abe S, Kakiuchi S, Kishuku M, Minakuchi K, Matsumoto T, Sone S.
- Journal Title
  
  Cancer Immunol Immunother 58
  
  Pages: 967-976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement.2008
- Author(s)
  Ogino H, Yano S, Kakiuchi S, Yamada T, Ikuta K, Nakataki E, Goto H, Hanibuchi M, Nishioka Y, Ryan A, Sone S.
- Journal Title
  
  Cancer Letters 265
  
  Pages: 55-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations.2008
- Author(s)
  Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakmura T, Ogino H, Kakiuchi S, Hanibuchi M, Nishioka Y, Uehara H, Mitsudomi T, Yatabe Y, Nakamura T, Sone S.
- Journal Title
  
  Cancer Res 68
  
  Pages: 9479-9487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in natural killer cell-depleted SCID mice.2008
- Author(s)
  Ogino H, Yano S, Kakiuchi S, Muguruma H, Ikuta K, Hanibuchi M, Uehara H, Tsuchida K, Sugino H, Sone S.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.2008
- Author(s)
  Maekawa Y, Minato Y, Ishifune C, Kurihara T, Kitamura A, Kojima H, Yagita H, Sakata-Yanagimoto M, Saito T, Taniuchi I, Chiba S, Sone S, Yasutomo K.
- Journal Title
  
  Nat Immunol 9
  
  Pages: 1140-1147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2.2008
- Author(s)
  Yamada T, Yano S, Ogino H, Ikuta K, Kakiuchi S, Hanibuchi M, Kanematsu T, Taniguchi T, Sekido Y, Sone S.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1603-1610
- NAID
  10024009864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Molecular pathogenesis and its therapeutic modalities of lung cancer metastasis to bone.2007
- Author(s)
  Sone S, Yano S.
- Journal Title
  
  Cancer Metastasis Rev 26
  
  Pages: 685-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Molecular pathogenesis and its therapeutic modalities of lung cancer metastasis to bone.2007
- Author(s)
  Sone, S., et. al.
- Journal Title
  
  Cancer and Metastasis Reviews 26
  
  Pages: 685-689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] CXCL9 and 11 in patients with pulmonary sarcoidosis: a role of alveolar macrophages.2007
- Author(s)
  Nishioka Y, Manabe K, Kishi J, Wang W, Inayama M, Azuma M, Sone S.
- Journal Title
  
  Clin Exp Immunol 49
  
  Pages: 317-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] The therapeutic efficacy of anti-vascular endothelial growth factor antibody, bevacizumab, and pemetrexed against orthotopically implanted human pleural mesothelioma cells in SCID mice.2007
- Author(s)
  Li Q, Yano S, Ogino H, Wang W, Uehara H, Nishioka Y, Sone S.
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 5918-5925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Novel orthotopic implantation model of human malignant pleural mesothelioma (EHMES-10 cells) highly expressing vascular endothelial growth factor and its receptor.2006
- Author(s)
  Nakataki E, Yano S, Matsumori Y, Goto H, Kakiuchi S, Muguruma H, Bando Y, Uehara H, Hamada H, Kito E, Yokoyama A, Sone S.
- Journal Title
  
  Cancer Sci 97
  
  Pages: 183-191
- NAID
  10018177286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer.2006
- Author(s)
  Takahashi K, Furukawa C, Takano A, Ishikawa N, Kato T, Hayama S, Suzuki C, Yasui W, Inai K, Sone S, Ito T, Nishimura H, Tsuchiya E, Nakamura Y, Daigo Y.
- Journal Title
  
  Cancer Res 66
  
  Pages: 9408-9419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] ZD6474, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, inhibits growth of experimental lung metastasis and production of malignant pleural effusions in a non-small cell lung cancer model.2006
- Author(s)
  Matsumori Y, Yano S, Goto H, Nakataki E, Wedge SR, Ryan AJ, Sone S.
- Journal Title
  
  Oncol Res 16
  
  Pages: 15-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages.2005
- Author(s)
  Kuniyasu H, Yano S, Sasaki T, Sasahira T, Sone S, Ohmori H.
- Journal Title
  
  Am J Pathol 166
  
  Pages: 751-759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Antitumor vascular strategy for controlling experimental metastatic spread of human small-cell lung cancer cells with ZD6474 in natural killer cell-depleted severe combined immunodeficient mice.2005
- Author(s)
  Yano S, Muguruma H, Matsumori Y, Goto H, Nakataki E, Edakuni N, Tomimoto H, Kakiuchi S, Yamamoto A, Uehara H, Ryan A, Sone S.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages: 8789-8798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Reveromycin A inhibits osteolytic bone metastasis of small-cell lung cancer cells, SBC-5, through an antiosteoclastic activity.2005
- Author(s)
  Muguruma H, Yano S, Kakiuchi S, Uehara H, Kawatani M, Osada H, Sone S.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages: 8822-8828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer.2005
- Author(s)
  Furukawa C, Daigo Y, Ishikawa N, Kato T, Ito T, Tsuchiya E, Sone S, Nakamura Y.
- Journal Title
  
  Cancer Res 65
  
  Pages: 7102-7110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Ebselen inhibits tumor necrosis factor- α -induced c-Jun N-terminal kinase activation and adhesion molecule expression in endothelial cells.2004
- Author(s)
  Yoshizumi M, Sone S, et al.
- Journal Title
  
  Exp Cell Res 292
  
  Pages: 1-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Sensitization of tumor-associated endothelial cell apotosis by the with cisplatin ・・・2004
- Author(s)
  Goto H, Sone S, et al.
- Journal Title
  
  Clin Cancer Res 10・22
  
  Pages: 7671-7676
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Expression of Toll-Like Receptor 4 on Dendritic Cells is Significant for Anticancer Effect of Dendritic Cell-Based Immunotherapy in Combination with an Active Component of OK-432, a Streptococcal Preparation.2004
- Author(s)
  Okamoto M, Sone S, et al.
- Journal Title
  
  Cancer Res 64
  
  Pages: 5461-5470
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Parathyroid hormone-related protein is responsible for production of bone metastasis ・・・2004
- Author(s)
  Miki T, Sone S, et al.
- Journal Title
  
  Int J Cancer 108・4
  
  Pages: 511-515
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Stimulation of human bronchial epithelial cells by IgE-dependent histamine-releasing factor ・・・2004
- Author(s)
  Yoneda K, Sone S, et al.
- Journal Title
  
  Am J Physil Lung Cell Mol Physiol 286・1
  
  Pages: 174-181
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Ebselen inhibits tumor necrosis factor-α-induced c-Jun N-terminal kinase activation and adhesion molecule ・・・2004
- Author(s)
  Yoshizumi, M., Sone S, et al.
- Journal Title
  
  Exp Cell Res 292(I):1-10,2004 292・1
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Synthesis and secretion of interleukin-15 by freshly isolated human bronchial epithelial cells ・・・2004
- Author(s)
  Ge N, Sone S, et al.
- Journal Title
  
  Int Arch Allergy Immunol 135・3
  
  Pages: 235-242
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Parathyroid hormone-related protein (PTHRP) is responsible for production of bone metastasis, but not visceral metastasis, by human small cell lung cancer SBC-5 cells in natural killer cell-depleted SCID mice.2004
- Author(s)
  Miki T, Sone, S, et al.
- Journal Title
  
  Int J Cancer 108
  
  Pages: 511-515
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Expression of toll-like receptor 4 on dendritic cells is significiant for anticancer effect of dendritic cell-based ・・・2004
- Author(s)
  Okamoto M, Sone S, et al.
- Journal Title
  
  Cancer Res 64・15
  
  Pages: 5461-5470
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Combined therapy with a new bisphosphonate, minodronate and chemotherapy for multiple organ metastasis of small cell lung cancer cells in severe combined immunodeficient mice.2003
- Author(s)
  Yano S, Sone S et al.
- Journal Title
  
  Clin Cancer Res 9
  
  Pages: 5380-5385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] A novel bisphosphonate minodronate (YM529) specifically inhibits osteolytic bone metastasis produced by human small-cell lung cancer cells in NK-cell depleted SCID mice.2003
- Author(s)
  Zhang H, Sone S, et al.
- Journal Title
  
  Clin Exp Metastasis 20
  
  Pages: 53-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Differential effects of IL-2 on the generation of alloreactive CTL mediated by murine and human dendritic cells.2003
- Author(s)
  Nishioka Y, Sone S, et al.
- Journal Title
  
  J Leukoc Biol 73
  
  Pages: 621-629
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Increased macrophage inflammatory protein-1 α and -1 β in BAL fluid of bronchiolitis obliterans organizing pneumonia.2003
- Author(s)
  Asano T, Tani K, Sone S, et al.
- Journal Title
  
  Respirology 8
  
  Pages: 461-466
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Genome-wide analysis of organ preferential metastasis of human small cell lung cancer in mice.2003
- Author(s)
  Kakiuchi S, Sone S, et al.
- Journal Title
  
  Mol Cancer Res. 1
  
  Pages: 485-489
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Molecular mechanisms of angiogenesis in non-small cell lung cancer, and therapeutics targeting related molecules.2003
- Author(s)
  Yano S, Sone S, et al.
- Journal Title
  
  Cancer Sci 94
  
  Pages: 479-485
- NAID
  10011689148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] Multifunctional interleukin-1 β promotes metastasis of human lung cancer cells in SCID mice via enhanced expression of adhesion-, invasion- and angiogenesis-related molecules.2003
- Author(s)
  Yano S, Sone, S, et al.
- Journal Title
  
  Cancer Sci 94
  
  Pages: 244-252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390256
[Journal Article] A Novel targeting therapy of malignant mesothelioma using anti- podoplanin antibody
- Author(s)
  Abe S, Morita Y, Kaneko MK, Hanibuchi M, Tsujimoto Y, Goto H, Kakiuchi S, Aono Y, Huang J, Sato S, Kishuku M, Taniguchi Y, Azuma M, Kawazoe K, Sekido Y, Yano S, Akiyama S, Sone S, Minakuchi K, Kato Y, Nishioka Y
- Journal Title
  
  J Immunol
  
  Volume: 2013
- URL
  http://www.jimmunol.org/content/early/2013/05/19/jimmunol.1300448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501048
[Presentation] がん転移制御と分子標的治療2010
- Author(s)
  曽根三郎
- Organizer
  第19回日本がん転移学会学術集会
- Place of Presentation
  金沢市文化ホール(石川県)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22390166
[Presentation] 肺癌の進展機構と分子標的治療2010
- Author(s)
  曽根三郎
- Organizer
  第107回日本内科学会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-22390166
[Presentation] 肺がん2010
- Author(s)
  曽根三郎
- Organizer
  第48回日本癌治療学会学術集会
- Place of Presentation
  グランドプリンスホテル京都(京都府)
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-22390166
[Presentation] Lung cancer: Update from early diagnosis to molecular -targeted and individualized therapy.2009
- Author(s)
  Sone S, et al.
- Organizer
  2009 Asian-Pacific Forum on Respiratory Diseases and West China Conference on Respiratory Diseases (招待講演)
- Place of Presentation
  成都市, 中国
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] Lung cancer : Update from early diagnosis to molecular-targeted and individualized therapy.2009
- Author(s)
  Saburo Sone, et al.
- Organizer
  2009 Asian-Pacific Forum on Respiratory Diseases and West China Conference on Respiratory Diseases
- Place of Presentation
  Jinjiang Hotel(中国四川省・成都市)
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] Validation of Molecular -targeted Therapy in Bone Metastasis Models of Lung Cancer.2009
- Author(s)
  Sone S, et al.
- Organizer
  VIII International Meeting on Cancer Induced Bone Disease (招待講演)
- Place of Presentation
  Sydney, Australia
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] Molecular mechanism of malignant pleural mesothelioma progression and its therapeutic implication2008
- Author(s)
  Saburo Sone, et.al.
- Organizer
  Joint Metastasis Research Society-AACR Conference on Metastasis
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2008-08-05
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] 呼吸器学-疾患モデルから分子標的治療への橋渡し研究-2008
- Author(s)
  曽根三郎
- Organizer
  第48回日本呼吸器学会学術講演会
- Place of Presentation
  神戸市
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] 悪性胸膜中皮腫の制御に向けたトランスレーショナルリサーチ2008
- Author(s)
  曽根三郎ら
- Organizer
  第17回日本臨床環境医学会学術集会
- Place of Presentation
  旭川市
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] 分子標的治療2008
- Author(s)
  曽根三郎
- Organizer
  第105回日本内科学会講演会
- Place of Presentation
  東京都
- Year and Date
  2008-04-11
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] Disease models to identify and validate molecular targets in lung cancer progression.2007
- Author(s)
  Sone S.
- Organizer
  ATS 2007 International Conference (Meet the Professor Seminer)
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] Disease models to identify and validate molecular targets in lung cancer progression.2007
- Author(s)
  Saburo Sone
- Organizer
  ATS 2007 International Conference
- Place of Presentation
  Moscone Center
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] Critical determinants of organ specific lung cancer metastasis.2006
- Author(s)
  Sone S.
- Organizer
  The 11th International Congress of the Metastasis Research Society iointed with the 15th Annual Meeting of Japanese Association for Metastasis Research(Presidential Lecture)
- Place of Presentation
  徳島
- Year and Date
  2006-09-03
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] 肺がん転移の悪性化要因に対する分子標的治療の展開2005
- Author(s)
  曽根三郎
- Organizer
  第59回日本口腔科学会(招請講演)
- Place of Presentation
  徳島
- Year and Date
  2005-04-22
- Data Source
  KAKENHI-PROJECT-17016051

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SONE Saburo 曽根 三郎

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Investigation of the novel anti-angiogenesis therapy in an orthotopic implantation mouse model of human malignant pleural mesothelioma cellsPrincipal Investigator

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Development of molecular targeted therapy for lung cancer metastasis considering characteristics of organ microenvironmentPrincipal Investigator

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Studies on new molecular therapeutic approach for radiation pneumonitisPrincipal Investigator

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Studies on the generation and application of fusion protein of single chain antibody for P-glycoprotein and chemokinePrincipal Investigator

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肺がんの転移・血管新生分子を標的とした生物学的制御法開発Principal Investigator

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肺がんの薬剤耐性と転移因子を分子標的とした免疫遺伝子治療Principal Investigator

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Cytokine production by human lung cancer and its paracrine regulationPrincipal Investigator

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SONE Saburo 曽根三郎