MASHIMA Yukihiko 真島行彦

Researcher Number	40157186
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006: 慶應義塾大学, 医学部, 非常勤講師 2005 – 2006: 慶應義塾大学, 医学部, 講師 1997 – 2003: 慶應義塾大学, 医学部, 助教授 1998: School of Medicine,KEIO University Associate Professor, 医学部, 助教授 1992 – 1995: 慶應義塾大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Ophthalmology Except Principal Investigator Ophthalmology / Ophthalmology
Keywords	Principal Investigator プロモーター / mutation / glaucoma / myocilin / 網膜アミンオキシダーゼ / ミオシリン / ISLR / 遺伝子変異 / 緑内障 / 染色体マッピング … More / ganglion / diagnosis / Invader assay / SNP / optineurin / 接着分子 / RAO遺伝子 / インベーダーアッセイ法 / レニン・アンギオテンシン系 / インベーダー法 / 遺伝子多型 / 遺伝子診断 / オプチニューリン / human amine oxidase / idebenone / Leber's disease / mause amine oxidase / promotor / retinal ganglion cell / ベクター / ヒトアミンオキシダーゼ / イデベノン / レーベル病 / マウスアミンオキシダーゼ / 網膜神経節細胞 / amine oxidase / gene cloning / retina / cDNA / アミンオキシダーゼ / シオシリン / 遺伝子クローニング / 網膜 / retinitis pigmentosa / cDNA library / retina cDNA / phosphodiesterase / peripherin / rhodopsin / retinal dystrophy / オルニチンアミノトランスフェレース / 脳回転状脈絡膜網膜萎縮 / 点突然変異 / Pmel 17 / SSCP法 / リカバリン / ペリフェリン / FISH法 / サブトラクション法 / 網脈絡膜変性症 / 網膜色素変性症 / cDNAライブラリー / 網膜特異的遺伝子 / ホスホジエステラーゼ / -ペリフェリン / ロドプシン / 網膜脈絡膜変性症 … More Except Principal Investigator multi-focal VEP / PCR / 遺伝子治療 / VEP / MRI / ミオシリン / heredity / gene / opticnerin / myocilin / normal-tention glaucoma / グリア / 緑内障 / 遺伝 / 遺伝子 / 視神経グリア細胞 / 正常眼圧緑内障 / visual evoked magnetic field: VEP / objective visual field / magnetoencephalographv MEG / visual evoked magnetic field:VEF / visual evoked magnetic field : VEF / 視覚誘発脳磁場 / magnetoencephalography MEG / 他覚的視野 / 多局所視覚誘発電位 / 脳磁図 / immunogene / artificial antibody / monoclonal antibody / gene therapy / intra ocular tumor / melanoma / イムノジーン / 人工一本鎖抗体 / モノクローナル抗体 / 眼内腫瘍 / 悪性黒色腫 / Immunohistochemistry / Molecular biology / Herpes / Virus / Chorioretinitis / Uveitis / ヘルペスウィルス / ヘルペスウイルス / ぶとう膜炎 / 免疫組織化学 / 分子生物学 / PCR法 / ヘルペス / ウイルス / 網脈絡膜炎 / ぶどう膜炎 / Idebenone / 11778 mutation / Heterplasmy / Mitochondrial DNA / Leber disease / SSCP / 遺伝的異質 / ヘテロプラスミー / 点突然変異 / レーベル視神経症 / 14484変異 / 3460変異 / イデベノン / 11778変異 / ヘテロプラスミ- / ミトコンドリアDNA / レ-ベル視神経症 / 多型 / プロモーター / マウス / チュブリン / 網膜視神経節細胞層 / アミンナキシダーゼ / アミンオキシダーゼ / 視神経 / 網膜特異的遺伝子 Less

Analysis of Expression and Function of Glaucoma-related Genes in Gila cells on Optic Nerve Head
- Principal Investigator
  
  OHTAKE Yuichiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KEIO UNIVERSITY
Study of glaucoma associated genes and development of DNA diagnostic panel and therapeutic vectorPrincipal Investigator
- Principal Investigator
  
  MASHIIMA Yukihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  KEIO UNIVERSITY
緑内障遺伝子ミオシリンの結合生体分子の解明とその分子間相互作用の解析
- Principal Investigator
  
  中村裕
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Study of theretinal ganglion cell specific gene, optic atrophy, and gene threrapyPrincipal Investigator
- Principal Investigator
  
  MASHIMA Yukihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Electrophysiological studies of refractory disease in retina, optic nerve and visual cortex
- Principal Investigator
  
  OGUCHI Yoshihisa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
網膜視神経節細胞に特異的に発現する新規遺伝子RAOの機能と遺伝性眼疾患との関連
- Principal Investigator
  
  IMAMURA Yutaka
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Cloning of retina-specific cDNAs and functional analysisPrincipal Investigator
- Principal Investigator
  
  MASHIMA Yukihiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Gene Therapy for Melanoma Using Artificial Antibody/DNA Complex
- Principal Investigator
  
  OHTAKE Yuichiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KEIO University
Molrcular biological study of hereditary retinochoroidal degenerationPrincipal Investigator
- Principal Investigator
  
  MASHIMA Yukohiko
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Moleculer cell biological and clinical study of hereditary optic neuropathy
- Principal Investigator
  
  OGUCHI Yoshihisa
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Molecular bilogical and immunohistochemical analysis on viral chorioretinitis
- Principal Investigator
  
  SUZUKI Saburosuke
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KEIO UNIVERSITY

All 2006 2005

All Journal Article

[Journal Article] Effect of topical unoprostone isopropyl on optic nerve head circulation in controls and in normal-tension glaucoma patients2006
- Author(s)
  Kimura I, Shinoda K, Ohtake Y, Mashima Y
- Journal Title
  
  Jpn J Ophthalmol. 49(4)
  
  Pages: 287-293
- NAID
  40006791808
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] SNPs and Interaction Analyses of Noelin 2, Myocilin, and Opteneurin Genes in Japanese Patients with Open-Angle Glaucoma.2006
- Author(s)
  Funayama T, Mashima Y, Ohtake Y. et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci 47(12)
  
  Pages: 5368-75
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] Paraoxonase 1 gene polymorphisms influence clinical features of open-angle glaucoma2006
- Author(s)
  Inagaki Y, Mashima Y, Ohtake Y. et al.
- Journal Title
  
  Graefes Arch Clin Exp Ophthalmol 244(8)
  
  Pages: 984-90
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma.2006
- Author(s)
  Funayama T, Mashima Y, Ohtake Y. et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci 47(12)
  
  Pages: 5368-5375
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] Polymorphism of beta-adrenergic receptors and susceptibility to open-angle glaucoma.2006
- Author(s)
  Inagaki Y, Mashima Y, et al.
- Journal Title
  
  Molecular Vision 12
  
  Pages: 673-680
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] Paraoxonase 1 gene polymorphisms influence clinical features of open-angle glaucoma2006
- Author(s)
  Inagaki Y, Mashima Y, Ohtake Y, et al.
- Journal Title
  
  Graefes Arch Clin Exp Ophthalmol 244(8)
  
  Pages: 984-990
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] Mitochondrial DNA mutations with Leber's hereditary optic neuropathy in Japanese patients with open-angle glaucoma. Jpn J Ophthalmol2006
- Author(s)
  Inagaki Y, Mashima Y, et al.
- Journal Title
  
  Jpn J Ophthalmol 50(2)
  
  Pages: 128-134
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] Mitochondrial DNA mutations with Leber's hereditary optic neuropathy in Japanese patients with open-angle glaucoma.2006
- Author(s)
  Inagaki Y, Mashima Y. et al.
- Journal Title
  
  Jpn J Ophthalmol. 50(2)
  
  Pages: 128-34
- NAID
  10020385905
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] Polymorphism of beta-adrenergic receptors and susceptibility to open-angle glaucoma.2006
- Author(s)
  Inagaki Y, Mashima Y. et al.
- Journal Title
  
  Molecular Vision 12
  
  Pages: 673-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] Paraoxonase 1 gene polymorphisms influence clinical features of open-angle glaucoma. Paraoxonase 1 gene polymorphisms influence clinical features of open-angle glaucoma.2006
- Author(s)
  Inagaki Y, Mashima Y, Funayama T, Ohtake Y, Fuse N, Yasuda N, Fukuchi T, Murakami A, Hotta Y.
- Journal Title
  
  Graefes Arch Clin Exp Ophthalmol. 13
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma2006
- Author(s)
  Funayama T, Mashima Y, Ohtake Y, et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci. 47(12)
  
  Pages: 5368-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591852
[Journal Article] Effect of topical unoprostone isopropyl on optic nerve head circulation in controls and in normal-tension glaucoma patients2005
- Author(s)
  Kimura I, Shinoda K, Ohtake Y, Mashima Y
- Journal Title
  
  Jpn J Ophthalmol. 49(4)
  
  Pages: 287-93
- NAID
  40006791808
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591852

1. OHTAKE Yuichirou (30233159)

# of Collaborated Projects: 6 results

# of Collaborated Products: 8 results
2. KUDHO Jun (80178003)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. SAGA Masamichi (00245557)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. IWATA Takeshi

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SUZUKI Saburosuke (40162945)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TANINO Tomohiko (50217147)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. IMAMURA Yutaka (20276215)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OGUCHI Yoshihisa (70051498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TAKAYANAGI Atsushi (80245464)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KIMURA Itaru (60296663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. IDEI Takeshi (90223130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KATSURA Hiroshi (40129391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NARITA Masaya (20237613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ANDO Yasutaka (90193119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NOMURA Masahiro (60172821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KUBOTA Ryo (00276338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ASAKAWA Shuichi (30231872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SHIMIZU Nobuyoshi (50162706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OHDE Hisao (70223881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KADO Hisashi (60278091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KUROSAKA Daijirou (20215099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中村裕 (90198242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 佐藤直樹 (80215821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 高橋弘毅 (20255524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 別院泰樹 (60255528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 井上理香子 (40255518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MASHIMA Yukihiko 真島 行彦

Research Projects

Research Products

Co-Researchers

Analysis of Expression and Function of Glaucoma-related Genes in Gila cells on Optic Nerve Head

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of glaucoma associated genes and development of DNA diagnostic panel and therapeutic vectorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

緑内障遺伝子ミオシリンの結合生体分子の解明とその分子間相互作用の解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of theretinal ganglion cell specific gene, optic atrophy, and gene threrapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Electrophysiological studies of refractory disease in retina, optic nerve and visual cortex

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

網膜視神経節細胞に特異的に発現する新規遺伝子RAOの機能と遺伝性眼疾患との関連

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cloning of retina-specific cDNAs and functional analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene Therapy for Melanoma Using Artificial Antibody/DNA Complex

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molrcular biological study of hereditary retinochoroidal degenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Moleculer cell biological and clinical study of hereditary optic neuropathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular bilogical and immunohistochemical analysis on viral chorioretinitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of topical unoprostone isopropyl on optic nerve head circulation in controls and in normal-tension glaucoma patients2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] SNPs and Interaction Analyses of Noelin 2, Myocilin, and Opteneurin Genes in Japanese Patients with Open-Angle Glaucoma.2006

Author(s)

Journal Title

Data Source

MASHIMA Yukihiko 真島行彦