TAKIGUCHI Masaki 瀧口正樹

Researcher Number	40179578
External Links
Affiliation (based on the past Project Information) *help	2016 – 2020: 千葉大学, 大学院医学研究院, 教授 2011 – 2015: 千葉大学, 医学(系)研究科(研究院), 教授 2011 – 2012: 千葉大学, 大学院・医学研究院, 教授 2007 – 2009: Chiba University, 大学院・医学研究院, 教授 2006: 千葉大学, 大学院医学研究院, 教授 … More 2002 – 2005: 千葉大学, 大学院・医学研究院, 教授 1999 – 2001: Chiba University, School of Medicine Professor, 医学部, 教授 1998: Chiba University, School of Medicine, Associate Professor, 医学部, 助教授 1991 – 1997: 熊本大学, 医学部, 助教授 1988 – 1990: Kumamoto Univ. Assistant Professor, 医学部, 講師 1986 – 1987: 熊本大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Environmental physiology(including physical medicine and nutritional physiology) / General medical chemistry / Applied health science / Pathological medical chemistry / Applied health science Except Principal Investigator General medical chemistry / Pathological medical chemistry / Surgical dentistry / Biological Sciences
Keywords	Principal Investigator EBP / C / オルニチンサイクル / 生物時計 / 概日リズム / HNF-4 / 転写調節 / COUP-TF / アルギナーゼ / 転写調節因子 … More / 時間生物学 / 遺伝子発現 / プロモーター / 肝臓選択的遺伝子発現 / オルニチントランスカルバミラーゼ / 尿素サイクル / enhancer-binding protein / CCAAT / 神経ペプチド / 糖新生 / 日周リズム / 摂食同調性時計 / 光同調性時計 / 視交叉上核 / 脂質合成 / SREBP / 肝臓 / グルココルチコイド / エンハンサー / hypoglycemia / hyperammonemia / ornithine cycle / metabolic disorder / gene disrupted mice / transcription factor / アンモニア / 低血糖 / 高アンモニア血症 / 代謝異常 / 標的遺伝子破壊マウス / Promoter / Arginase / Ornithine cycle / Liver / Transcriptional regulation / 神経ぺプチド / 代謝調節 / グルカゴン / 生体分子医学 / 発現制御 / 遺伝子 / 遺伝子発現制御 / シグナル伝達 / 時計遺伝子 / 行動学 / ジスルフィド結合 / IGF-1R / SLRP / 創薬 / 計算化学 / ジスルフド結合 / 合成ペプチド / 細胞増殖 / EGFR / 細胞外マトリックスタンパク / デコリン / プロテアソーム / 酸化的リン酸化 / マイクロアレイ解析 / 栄養組成 / 栄養素 / 遺伝子標的破壊マウス / セクレトグラニンII / 尿素合成 / 光応答性 / 生活習慣病 / Spot14 / 制限給餌 / サブトラクション / 長期抑圧 / 長期増強 / CA1 / 海馬 / 可塑性 / 肝臓選択的転写調節 … More Except Principal Investigator オルニチントランスカルバミラーゼ / stathmin / maspin / マイクロアレイ / 尿素サイクル / チロシンキナーゼ / 延長ペプチド / 遺伝子クローニング / cDNAクローニング / 3-ケトアシルCoAチオラーゼ / cDNA / 遺伝子発現プロファイリング / オルニチントランスカルバミラ-ゼ / RFLP / salivary gland tumor / microarray analysis / 唾液腺癌 / マイクロアレイ解析 / Presequence / Ornithine transcarbamylase / サイトソル因子 / ミトコンドリア蛋白質前駆体 / 転写調節 / インスリン受容体 / 内在性ミトコンドリア識別シグナル / cDNAの構造 / 遺伝子の構造 / プロモーター / トランスジェニックマウス / High expression in E. coli / Reactivation experiments / Presequence binding factor / Cytosolic factor / Ornithine trans-carbamylase / Mitochondrial protein precursor / Mitichondrial protein import / 非切断性ミトコンドリア識別シグナル / 精製前駆体 / オキソアシルCoAチオラーゼ / 大腸菌での大量発現 / 活性化実験 / PBF / 蛋白質のミトコンドリア移行 / Diabetes mellitus / Hereditary hyperammonemia / Urea cycle diseases / インスリンレセプター / 尿素サイクル酵素群 / DNA診断 / インスリン受容体異常型糖尿病 / 先天性高アンモニア血症 / 先天性尿素サイクル病 / Regulation of the gene expression / Human insulin receptor gene / site directed mutagenesis / インスリン受容体遺伝子 / インスリン作用機構 / 糖尿病 / インスリンレセプター遺伝子 / non-cleavable signal,cDNA sequence / presequence / mitochondrial protein import / 3-oxoacyl-CoA thiolase / 蛋白質のミトコンドリア局在化 / ヒドロキシアシルCoAデヒドロゲナーゼ / ミトコンドリア蛋白質遺伝子 / 3ーケトアシルCoAチオラーゼ / オルニテントランスカルバミラーゼ / オルニチントランスカルバミナーゼ / adenoid cystic carcinoma / 唾液腺腫瘍 / 線様嚢胞癌 / 腺様嚢胞癌 / pleomorphic adenoma / squamous cell carcinoma / oral cancer / 腺癌 / 庸平上皮癌 / 遺伝子機能評価 / 扁平上皮癌 / 口腔癌 / Immunostaining method / lipopolysaccharide / astrocyte / central nervous system / nitric oxide synthase / nitric oxide / サブトラクション / 長期抑圧 / 長期増強 / 海馬 / 可塑性 / 肝臓 / 細胞分化 / 遺伝子発現 / 免疫染色法 / リポ多糖 / アストロサイト / 中枢神経系 / 一酸化窒素合成酵素 / 一酸化窒素 / Liver funcion test / Liver disease / ELISA / Mitochondria / Urea cycle / Ornithinecarbamoyltransferase / カルバミリン酸合成酵素 / トランスアミナーゼ / ELISA法 / 肝障害マーカー / 肝機能検査 / 肝疾患 / 酵素免疫測定法 / ミトコンドリア / オルニチンカルバモイルトランスフェラーゼ / Hsp70 / PBF (presequence binding factor) / Cytosolic factors / Mitochondrial biogenesis / Intracellular transport / Precursor proteins / Presequence binding factor(PBF) / PBF(presequence binding factor) / プレシ-クエンス / hsp70 / PBF(presequence binding factor / 蛋白質の膜透過 / 組織特異的遺伝子発現 / 先天性酵素欠損症 / 分子進化 / レンズ蛋白質 / アルギニン合成酵素 / 尿素サイクル酵素 / δクリスタリン / アルギニノコハク酸リアーゼ / 細胞増殖 / 細胞増殖因子受容体 / キメラ受容体 / プロセシングプロテアーゼ / ミトコンドリア識別と膜透過 / ミトコンドリア形成 / 唾液腺 / 視交差上核 / CREB / long-term potentiation / MAPキナーゼ / CaMキナーゼIV / メラトニン / グルタミン酸 / 松果体 / フィブリノーゲン / 概日リズム / 視交叉上核 / 時計遺伝子 / CaMキナーゼII / アルギナーゼ / 尿酸排出型動物 / 尿素排出型動物 / アンモニア排出型動物 / 窒素排出 / プロモ-タ- / エンハンサ- / アルギナ-ゼ / 尿素サイクル酵素異常症 Less

Hierarchical control mechanism in the formation of diurnal rhythms of metabolism and behavior by nutrition and locomotionPrincipal Investigator
- Principal Investigator
  
  Takiguchi Masaki
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Chiba University
Investigation of mechanism for Aschoff's rulePrincipal Investigator
- Principal Investigator
  
  Takiguchi Masaki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Chiba University
Regulation of daily rhythms for behavior-metabolism links by light and nutritionPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masaki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Chiba University
Gene regulation by amino acidsPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Chiba University
Etiological mechanism of lifestyle-related diseases caused by disordered daily rhythmsPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masaki
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Chiba University
デコリンのN末端ペブチドはいかにして細胞増殖を両方性に制御するかPrincipal Investigator
- Principal Investigator
  
  瀧口正樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Chiba University
光刺激はいかにして肝臓の遺伝子発現を制御するかPrincipal Investigator
- Principal Investigator
  
  瀧口正樹
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Chiba University
唾液腺組織のcDNAライブラリー作成と唾液腺疾患用DNAチップの開発作製
- Principal Investigator
  
  TANZAWA Hideki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Search for oral cancer specific genes and molecular cloning using in-house cDNA microaray
- Principal Investigator
  
  SHIBA Masashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Gene profiling in adenoid cystic carcinoma cells using in-house cDNA microaray
- Principal Investigator
  
  YOKOE Hidetaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
時計遺伝子産物のリン酸化に関わる分子素過程の解明
- Principal Investigator
  
  福永浩司
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
  Kumamoto University
Gene cascades in cell differentiation and plasticity
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
Liver disorders in mice lacking transcription factorsPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masaki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Chiba University
  Kumamoto University
神経活動を制御する階層性遺伝子支配の解析Principal Investigator
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
転写調節因子群の協調による肝臓選択的転写の制御機構Principal Investigator
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
オルニチンサイクル酵素遺伝子の転写調節機構Principal Investigator
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
転写調節因子群の協調による肝臓選択的転写の制御機構Principal Investigator
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
窒素排出の分子進化
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
転写調節因子群の協調による肝臓選択的転写の規定機構Principal Investigator
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Regulatory mechanisms for liver-selective transcription of genes for ornithine cycle enzymesPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masaki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
尿素サイクル酵素遺伝子の肝臓特異的転写を制御する因子Principal Investigator
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Development of enzyme-linked immunosorbent assay as a liver function test
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
尿素サイクル酵素遺伝子の肝特異的発現を制御する因子Principal Investigator
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
尿素サイクル酸素遺伝子の肝特異的発現を制御する因子Principal Investigator
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Transport of Proteins into Mitochondria
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
トランスジェニックマウスを用いた尿素サイクル酵素異常症の研究
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
細胞増殖因子受容体チロシンキナーゼ細胞増殖の制御機構
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokushima
カルバミルリン酸をとりまく代謝酵素系遺伝子の分子進化
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
トランスジェニックマウスを用いた尿素サイクル酵素異常症の研究
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Molecular mechanism of protein import into mitochondria
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  KUMAMOTO UNIVERSITY
核支配ミトコンドリア蛋白質遺伝子の構造と発現
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kumamoto University
新しい機能をもつ受容体作製の基礎的研究
- Principal Investigator
  
  蛯名洋介
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
核支配ミトコンドリア蛋白質遺伝子の構造と発現
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kumamoto University
Structures, Expression and their Desorders of the Genes for Mitochondrial Proteins
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
Structure and the regulation of the gene expression of the human insulin receptor gene and its abnormalities
- Principal Investigator
  
  EBINA Yousuke
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokushima Univ.
  Kumamoto University
Development of DNA diagnosis of urea cycle diseases and diabetes due to insulin receptor abnormality
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University Medical School

All 2019 2017 2015 2014 2013 2012 2011 2009 2008 2007 2006 2003

All Journal Article Presentation Patent

[Journal Article] Systemic oscillator-driven and nutrient-responsive hormonal regulation of daily expression rhythms for gluconeogenic enzyme genes in the mouse liver.2019
- Author(s)
  Taira A, Arita E, Matsumoto E, Oohira A, Iwase K, Hiwasa T, Yokote K, Shibata S, Takiguchi M.
- Journal Title
  
  Chronobiology International
  
  Volume: 36(5). Issue: 5 Pages: 591-615
- DOI
  10.1080/07420528.2019.1570246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26220201, KAKENHI-PROJECT-16H03257, KAKENHI-PROJECT-15K01842
[Journal Article] The pluripotent stem-cell marker alkaline phosphatase is highly expressed in refractory glioblastoma with DNA hypomethylation.2017
- Author(s)
  Iwadate, Y., Suganami, A., Tamura, Y., Matsutani, T., Hirono, S., Shinozaki, N., Hiwasa, T., Takiguchi, M., and Saeki, N.
- Journal Title
  
  Neurosurgery
  
  Volume: 80 Issue: 2 Pages: 248-248
- DOI
  10.1093/neuros/nyw026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03257, KAKENHI-PROJECT-26460505, KAKENHI-PROJECT-16K08542, KAKENHI-PROJECT-16K10750
[Journal Article] Identification of stroke-associated-antigens via screening of recombinant proteins from the human expression cDNA library (SEREX)2015
- Author(s)
  Machida, T., Kubota, M., Kobayashi, E., Iwadate, Y., Saeki, N., Yamaura, A., Nomura, F., Takiguchi, M., Hiwasa, T.
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 13 Issue: 1 Pages: 71-71
- DOI
  10.1186/s12967-015-0393-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-25670115, KAKENHI-PROJECT-26460505
[Journal Article] Novel serum autoantibodies against talin1 in multiple sclerosis: Possible pathogenetic roles of the antibodies2015
- Author(s)
  Muto M, Mori M, Hiwasa T, Takiguchi M, Iwadate Y, Uzawa A, Uchida T, Masuda H, Sugimoto K, Kuwabara S.
- Journal Title
  
  Journal of Neuroimmunology
  
  Volume: 284 Pages: 30-36
- DOI
  10.1016/j.jneuroim.2015.05.005
- NAID
  120007088198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09333, KAKENHI-PROJECT-26460505, KAKENHI-PROJECT-25670115
[Journal Article] Up-regulation of growth-inhibitory or tumor suppressive genes by overexpression of C/EBPα or C/EBPβ in ras-transformed NIH3T3 cells.2015
- Author(s)
  Kuroiwa, N., Iwase, K., Morii, S., Takiguchi, M., and Hiwasa, T.
- Journal Title
  
  Integr. Mol. Med.
  
  Volume: 2 Pages: 150-157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670115
[Journal Article] Elevated serum antibody levels against cyclin L2 in patients with esophageal squamous cell carcinoma.2015
- Author(s)
  Shimada H, Ito M, Kagaya A, Shiratori T, Kuboshima M, Suzuki M, Liu TL, Nabeya Y, Matsubara H, Matsushita K, Nomura F, Takiguchi M, Hiwasa T
- Journal Title
  
  J Cancer Sci Ther
  
  Volume: 7(2) Issue: 02 Pages: 60-66
- DOI
  10.4172/1948-5956.1000326
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460505, KAKENHI-PROJECT-25670115
[Journal Article] Identification of the p53-responsive element in the promoter region of the human decorin gene.2015
- Author(s)
  Hiwasa T, Iwase K, Suichi T, Hino Y, Kimura R, Shinmen N, Takiguchi M
- Journal Title
  
  Mol Biol
  
  Volume: 4 Issue: 01 Pages: 1-1
- DOI
  10.4172/2168-9547.1000124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460505, KAKENHI-PROJECT-25670115
[Journal Article] The secretogranin II gene is a signal integrator of glutamate and dopamine inputs.2014
- Author(s)
  Iwase, K., Ishihara, A., Yoshimura, S., Andoh, Y., Kato, M., Seki, N., Matsumoto, E., Hiwasa, T., Muller, D., Fukunaga, K., and Takiguchi, M.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 128 Issue: 2 Pages: 233-245
- DOI
  10.1111/jnc.12467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-25670115, KAKENHI-PROJECT-25870296
[Journal Article] Inhibition of cell growth by nuclear receptor COUP-TFI: Possible involvement of decorin in growth inhibition2014
- Author(s)
  Morii, S., Kato, M., Seki, N., Shinmen, N., Iwase, K., Takiguchi, M., Hiwasa, T.
- Journal Title
  
  Biochemistry & Physiology
  
  Volume: S4
- DOI
  10.4172/2168-9652.s4-001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-25670115, KAKENHI-PROJECT-26460505
[Journal Article] Circulating anti-filamin C autoantibody as a potential serum biomarker for low-grade gliomas2014
- Author(s)
  Adachi-Hayama, M., Adachi, A., Shinozaki, N., Matsutani, T., Hiwasa, T., Takiguchi, M., Saeki, N., Iwadate, Y.
- Journal Title
  
  BMC Cancer
  
  Volume: 14 Issue: 1 Pages: 452-452
- DOI
  10.1186/1471-2407-14-452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-25670115, KAKENHI-PROJECT-26460505
[Journal Article] Efficient subtractive cloning of genes activated by lipopolysaccharide and interferon γ in primary-cultured cortical cells of newborn mice.2013
- Author(s)
  Miyauchi, O., Iwase, K., Itoh, K., Kato, M., Seki, N., Braissant, O., Bachmann, C., Shozu, M., Sekiya, S., Osada, H., and Takiguchi, M.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 11 Pages: e79236-e79236
- DOI
  10.1371/journal.pone.0079236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-23659772, KAKENHI-PROJECT-25253092, KAKENHI-PROJECT-25670115
[Journal Article] Autologous antibody to src-homology 3-domain GRB2-like 1 specifically increases in the sera of patients with low-grade gliomas2012
- Author(s)
  5. Matsutani T, Hiwasa T, Takiguchi M, Oide T, Kunimatsu M, Saeki N, Iwadate Y
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 31 Issue: 1 Pages: 31-85
- DOI
  10.1186/1756-9966-31-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591606, KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-23659147
[Journal Article] Identification of a novel SEREX antigen family, ECSA, in esophageal squamous cell carcinoma2011
- Author(s)
  Kagaya A, Shimada H, Shiratori T, et al.(2番目/17人中)
- Journal Title
  
  Proteome Science
  
  Volume: 9 Issue: 1 Pages: 31-31
- DOI
  10.1186/1477-5956-9-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591717, KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-23659147
[Journal Article] Functional similarity of anticancer drugs by MTT Bioassay2011
- Author(s)
  Hiwasa, T., Utsumi, T., Yasuraoka, M., Hanamura, N., Shimada, H., Nakajima, H., Kitagawa, M., Iwadate, Y., Goto, K.I., Takeda, A., Ohtsuka, K., Ariga, H., and Takiguchi, M.
- Journal Title
  
  J. Cancer Sci. Therapy
  
  Volume: 3 Pages: 250-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659147
[Journal Article] Calpain regulates thymidylate synthase-5-fluoro-dUMP complex levels associated with response to 5-fluorouracil in gastric cancer cells2011
- Author(s)
  Nabeya, Y., Suzuki, T., Furuya, A., Koide, N., Ohkoshi, M., Takiguchi, M., Ochiai, T., Matsubara, H., Hiwasa, T.
- Journal Title
  
  Cancer Science
  
  Volume: 102 Issue: 8 Pages: 1509-1515
- DOI
  10.1111/j.1349-7006.2011.01978.x
- NAID
  10030242173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-23659147
[Journal Article] Calpain regulates thymidylate synthase-5-fluoro-dUMP complex levels associated with response to 5-fluorouracil in gastric cells2011
- Author(s)
  Nabeya, Y., Suzuki, T., Furuya, A., Koide, N., Ohkoshi, M., Takiguchi, M., Ochiai, T., Matsubara, H., and Hiwasa, T.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1509-1515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659147
[Journal Article] Functional similarity of anticancer drugs by MTT bioassay2011
- Author(s)
  Hiwasa T, Iwadate Y, et al.
- Journal Title
  
  J Cancer Science & Therapy
  
  Volume: 3 Issue: 10 Pages: 250-255
- DOI
  10.4172/1948-5956.1000099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591606, KAKENHI-PROJECT-23390048, KAKENHI-PROJECT-23659147
[Journal Article] Activation of NFAT signal by p53-K120R mutant2009
- Author(s)
  Shinmen, N., Koshida, T., Kumazawa, T., Sato, K., Shimada, H., Matsutani, T., Iwadate, Y., Takiguchi, M., Hiwasa, T.
- Journal Title
  
  FEBS Lett. 583
  
  Pages: 1916-1922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Insight into estrogenicity of phytoestrogens using in silico simulation2009
- Author(s)
  Sugiyama, H., Kumamoto, T., Suganami, A., Nakanishi, W., Sowa, Y., Takiguchi, M., Ishikawa, T., Tamura, Y.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 379
  
  Pages: 139-144
- NAID
  120006348191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Hepatoblast-like cells enriched from mouse embryonic stem cells in medium without glucose, pyruvate, arginine, and tyrosine2008
- Author(s)
  Tomizawa, M., Toyama, Y., Ito, C., Toshimori, K., Iwase, K., Takiguchi, M., Saisho, H., Yokosuka, O.
- Journal Title
  
  Cell Tissue Res. 333
  
  Pages: 17-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Expression of the WT1 gene-KTS domain isoforms suppresses the invasive ability of human lung squamous cell carcinoma cells2008
- Author(s)
  Moriya, S., Takiguchi, M., Seki, N.
- Journal Title
  
  Int.J.Oncol. 32
  
  Pages: 349-356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Multifactorial regulation of daily rhythms in expression of the metabolically responsive gene Spot14 in the mouse liver2007
- Author(s)
  Ishihara, A., Matsumoto, E., Horikawa, K., Kudo, T., Sakao, E., Nemoto, A., Iwase, K., Sugiyama, H., Tamura, Y., Shibata, S., Takiguchi, M.
- Journal Title
  
  J.Biol.Rhythms 22
  
  Pages: 324-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Multifactorial regulation of daily rhythms in expression of the metabolically responsive gene Spot14 in the mouse liver2007
- Author(s)
  Ishihara,A., Matsumoto,E., Horikawa,K., Kudo,T., Sakao,E., Nemoto,A., Iwase,K., Sugiyama,H., Tamura,Y., Shibata,S., Takiguchi,M.
- Journal Title
  
  J. Biol. Rhythms 2 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Up-regulation of genes for oxidative phosphorylation and protein turnover in diabetic mouse retina2006
- Author(s)
  Adachi-Uehara,N., Kato,M., Nimura,Y., Seki,N., Ishihara,A., Matsumoto,E., Iwase,K., Ohtsuka,S., Kodama,H., Mizota,A., Yamamoto,S., Adachi-Usami,E., Takiguchi,M.
- Journal Title
  
  Exp. Eye Res. 8 3
  
  Pages: 849-857
- NAID
  120006348189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Activation of genes for growth factor and cytokine pathways late in chondrogenic differentiation of ATDC5 cells2006
- Author(s)
  Osawa, A., Kato, M., Matsumoto, E., Iwase, K., Sugimoto, T., Matsui, T., Ishikura, H., Sugano, S., Kurosawa, H., Takiguchi, M., Seki, N.
- Journal Title
  
  Genomics 88
  
  Pages: 52-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Up-regulation of genes for oxidative phosphorylation and protein turnover in diabetic mouse retina2006
- Author(s)
  Adachi-Uehara, N., Kato, M., Nimura, Y., Seki, N., Ishihara, A., Matsumoto, E., Iwase, K., Ohtsuka, S., Kodama, H., Mizota, A., Yamamoto, S., Adachi-Usami, E., Takiguchi, M.
- Journal Title
  
  Exp.Eye Res. 83
  
  Pages: 849-857
- NAID
  120006348189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Relationship between pancreatic secretory trypsin inhibitor and early recurrence of intrahepatic cholangiocarcinoma following surgical resection2006
- Author(s)
  Tonouchi, A., Ohtsuka, M., Ito, H., Kimura, F., Shimizu, H., Kato, M., Nimura, Y., Iwase, K., Hiwasa, T., Seki, N., Takiguchi, M., Miyazaki, M.
- Journal Title
  
  Am.J.Gastroenterol. 101
  
  Pages: 1601-1610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis2006
- Author(s)
  Kai, N., Iwase, K., Imai, K., Nakahira, E., Soma, M., Ohtsuka, S., Yagi, T., Kobayashi, K., Koga, H., Takiguchi, M., Yuasa, S.
- Journal Title
  
  Brain Res. 1073-1074
  
  Pages: 60-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] Enhancement of chemosensitivity toward peplomycin by calpastatin-stabilized NF-kappaB p65 in esophageal carcinoma cells : possible involvement of Fas/Fas-L synergism2006
- Author(s)
  Liu, T. L., Shimada, H., Ochiai, T., Shiratori, T., Lin, S. E., Kitagawa, M., Harigaya, K., Maki, M., Oka, M., Abe, T., Takiguchi, M., Hiwasa, T.
- Journal Title
  
  Apoptosis 11
  
  Pages: 1025-1037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300228
[Journal Article] In-house cDNA microarray analysis of gene expression profiles involved in SCC cell lines.2003
- Author(s)
  Moriya T, Seki N, Shimada K, Kato M, Yakushiji T, Nimura Y, Uzawa K, Takiguchi M
- Journal Title
  
  Int J Mol Med. 12
  
  Pages: 429-435
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390608
[Journal Article] In-house cDNA microarray analysis of gene expression profiles involved in SCC cell lines.2003
- Author(s)
  Moriya T, Seki N, Shimada K, Kato M, Yakushiji T, Nimura Y, Uzawa K, Takiguchi M, Tanzawa H.
- Journal Title
  
  Int J Mol Med 12
  
  Pages: 429-435
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390608
[Patent] 整長cDNA 由来両鎖cRNA サブトラクション方法2012
- Inventor(s)
  瀧口正樹,岩瀬克郎,大塚里子,坂尾詠子,宮内修
- Industrial Property Rights Holder
  瀧口正樹,岩瀬克郎
- Filing Date
  2012-07-27
- Data Source
  KAKENHI-PROJECT-23659147
[Patent] 微量mRNA及びcDNAの増幅方法2006
- Inventor(s)
  瀧口正樹
- Industrial Property Rights Holder
  独立行政法人科学技術振興機構
- Acquisition Date
  2006-09-15
- Data Source
  KAKENHI-PROJECT-18300228
[Patent] 微量mRNA及びcDNAの増幅方法2006
- Inventor(s)
  滝口,正樹
- Industrial Property Rights Holder
  独立行政法人科学技術振興機構
- Filing Date
  2006-09-15
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] アルファライザ法による食道癌SEREX抗原の再評価2012
- Author(s)
  日和佐隆樹(発表者),劉天玲,島田英昭,松原久裕,瀧口正樹
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23659147
[Presentation] 脳梗塞と糖尿病の診断に有用な血清抗体マーカーの同定2012
- Author(s)
  日和佐隆樹(発表者),張暁萌,薦田操,瀧口正樹,森雅裕,鵜沢顕之,武藤真弓,桑原聡,竹本稔,小林一貴,横手幸太郎,青墳章代,和田猛,吉川由利子,片山薫,町田利生,土居洋文,工藤孝,中村利華,冨吉郷,新免奈津子,吉田涼,太田優子,黒田英行
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-23659147
[Presentation] 脳梗塞関連ペプチドアレイ法を用いた動脈硬化血清抗体マーカーの探索2011
- Author(s)
  日和佐隆樹(発表者),國松己歳,伊藤舞,小越朱根,張暁萌,町田利生,中村利華,冨吉郷,新免奈津子,吉田涼,太田優子,黒田英行,瀧口正樹
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23659147
[Presentation] マウス肝臓における代謝応答性Spot14遺伝子の発現の日周リズムに見られる多因子制御2007
- Author(s)
  松本絵里子, 石原顕紀, 堀川和政, 工藤崇, 坂尾詠子, 根本あや子, 岩瀬克郎, 杉山肇, 田村裕, 柴田重信, 瀧口正樹
- Organizer
  第80回日本生化学会大会・第30回日本分子生物学会年
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] Computer Assisted Drug Design:Decorin-like Peptides as Anticancer Drug2007
- Author(s)
  田村裕, 安達統衛, 杉山肇, 塩原紀行, 日和佐隆樹, 瀧口正樹
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] VDAC1とBaxによるp53の活性制御機構2007
- Author(s)
  日和佐隆樹, 越田敏史, 加賀谷暁子, 松谷智郎, 瀧口正樹
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] 扁平上皮癌抗原のSEREXスクリーニングによる同定と機能解析2007
- Author(s)
  加賀谷暁子, 島田英明, 落合武徳, 瀧口正樹, 日和佐隆樹
- Organizer
  第80回日本生化学会大会・第30回日本分子生物学会年会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] 扁平上皮癌SEREX抗原サイクリンL2の同定と機能解析2007
- Author(s)
  加賀谷暁子, 島田英明, 白鳥亨, 落合武徳, 瀧口正樹, 日和佐隆樹
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] 扁平上皮癌抗原のSEREXmakorinlの同定と機能解析2007
- Author(s)
  白鳥亨, 島田英明, 加賀谷暁子, 落合武徳, 瀧口正掛, 日和佐隆樹
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] 神経伝達物質によるセクレトグラニンII遺伝子の発現制御機構2007
- Author(s)
  岩瀬克郎, 吉村俊太郎, 日和佐隆樹, 瀧口正樹
- Organizer
  第80回日本生化学会大会・第30回日本分子生物学会年会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] グリオーマ特異抗原の検索2007
- Author(s)
  松谷智郎, 岩立康雄, 日和佐隆樹, 瀧口正樹, 佐伯直勝
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] 食道扁平上皮癌SEREX抗原CU-EC-10に対する血清抗体の臨床病理学的意義2007
- Author(s)
  島田英明, 加賀谷暁子, 白鳥亨, 瀧口正樹, 野村文夫, 日和佐隆樹
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] Nicastrinによるp53の活性制御機構2007
- Author(s)
  越田敏史, 日和佐隆樹, 瀧口正樹
- Organizer
  第80回日本生化学会大会・第30回日本分子生物学会年会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18300228
[Presentation] Nicastrinによるp53の活性制御機構2007
- Author(s)
  越田敏史, 日和佐隆樹, 松谷智郎, 瀧口正樹
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18300228

1. MORI Masataka (40009650)

# of Collaborated Projects: 15 results

# of Collaborated Products: 0 results
2. IWASE Katuro (80322030)

# of Collaborated Projects: 6 results

# of Collaborated Products: 14 results
3. EBINA Yousuke (00112227)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. MATUMOTO Eriko (20422256)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
5. AMAYA Yoshihiro (50193032)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. HIWASA Takaki (30260251)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
7. TANZAWA Hideki (50236775)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. SEKI Naohiko (50345013)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
9. SHIRASAWA Hiroshi (00216194)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. ARITA Emiko

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. TAIRA Akiko

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. TAMURA Yutaka (50263174)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
13. 福永浩司 (90136721)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 宮本英七 (50109659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. OOHIRA Ayano

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. TAMAI Keiko

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. MORI Shunsuke (70230068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MORI Kaoru (20230063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. FUJIYAMA Shigetoshi (20109656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. GOTOH Tomomi (20264286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TERADA Kazutoyo (00253724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SHIBA Masashi (20301096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YOKOE Hidetaka (70261930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 森山芳則 (10150658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 鵜澤一弘 (30302558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 守屋彰悟 (00793837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 菅波晃子 (10527922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. KIMURA RISA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. TASHIRO Hidetoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. WATAZU Yoshifumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. DAS Atze T.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. LAMARS Wouter H.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. HAKVOORT The

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. LAMERS Woute

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. MASAHIRO Mori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. UZAWA Akiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. UCHIDA Tomohiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. MASUDA Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. SUGIMOTO Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. IWADATE Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
41. 島田英昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 柴田重信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKIGUCHI Masaki 瀧口 正樹

Research Projects

Research Products

Co-Researchers

Hierarchical control mechanism in the formation of diurnal rhythms of metabolism and behavior by nutrition and locomotionPrincipal Investigator

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Investigation of mechanism for Aschoff's rulePrincipal Investigator

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Regulation of daily rhythms for behavior-metabolism links by light and nutritionPrincipal Investigator

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Gene regulation by amino acidsPrincipal Investigator

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Etiological mechanism of lifestyle-related diseases caused by disordered daily rhythmsPrincipal Investigator

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デコリンのN末端ペブチドはいかにして細胞増殖を両方性に制御するかPrincipal Investigator

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光刺激はいかにして肝臓の遺伝子発現を制御するかPrincipal Investigator

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Liver disorders in mice lacking transcription factorsPrincipal Investigator

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神経活動を制御する階層性遺伝子支配の解析Principal Investigator

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TAKIGUCHI Masaki 瀧口正樹