Keiichi Watanabe 渡邉啓一

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渡邉啓一ワタナベケイイチ

WATANABE Keiichi 渡邉啓一

WATANABE Kenichi 渡邉啓一

渡邊啓一ワタナベケイイチ

渡辺啓一ワタナベケンイチ

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Researcher Number	40191754
Other IDs
Affiliation (Current)	2025: 九州栄養福祉大学, 食物栄養学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 佐賀大学, 農学部, 教授 2012: 佐賀大学, 農学部, 教授 2002 – 2006: Saga University, Applied Biological Science, Professor, 農学部, 教授 2001 – 2002: 佐賀大学, 農学部, 助教授 1994 – 1997: 佐賀大学, 農学部, 助教授 1989 – 1991: 佐賀大学, 農学部, 助教授 1987 – 1988: 九州大学, 農学部, 助手
Review Section/Research Field	Principal Investigator 応用生物化学・栄養化学 / 応用微生物学・応用生物化学 / Applied biochemistry Except Principal Investigator Basic Section 43040:Biophysics-related / Immunology / Basic veterinary science/Basic zootechnical science / 物性一般(含基礎論)
Keywords	Principal Investigator subtilisin / 好冷細菌 / cold-adaptation / psychrotroph / サチライシン / タンパク質工学 / X線結晶構造解析 / 低温適応 / プロテアーゼ / Shewanella … More / flexibility of enzyme / cold activity / cold enzyme / acetate kinase / Pseudoalteromonass / ドメイン構造 / 構造ゆらぎ / ゆらぎ / X線結晶構造 / 低温プロテアーゼ / Pseudoalteromonas / 結晶構造 / 結晶構造解析 / Trematomus bernacchii / 酵素構造の柔軟性 / 乳酸デヒドロゲナーゼ / 酢酸キナーゼ / ズブチリシン / 低温適応酵素 / structural evolution / stability of protein / protease / cold-enzyme / cold-activity / タンパク質変性 / βターン / 構造進化 / タンパク質安定性 / 低温酵素 / 低温活性 / Protein engineering. / Pokeweed antiviral protein, / Ricin A-chain, / X-ray crystallography, / Ribosome-inactivating protein, / RNA N-glycosidase, / リボソーム不活性化タンパク質 / RNAN-グリコシダーゼ / アメリカヤマゴボウ抗ウイルスタンパク質 / リシンA鎖 / リボゾーム不活性化タンパク質 / RNA N-グリコシダーゼ / Alteromonas / 南極 … More Except Principal Investigator LPS / MD-2 / 好冷細菌 / 構造解析 / 生体関連化学 / 熱安定性 / 構造生物学 / 低温適応 / 生体分子 / 熱安定酵素 / スピンラベル / 電子スピン共鳴法 / タンパク質工学 / X線結晶構造解析 / 低温適応酵素 / 電子スピン共鳴 / 生物物理 / 構造生物化学 / 酵素 / pCAGG-S1 vector / epitope / NF κ B reporter gene / E coli expression / fusion protein / pET32 vector / pCAG-S1ベクター / pCAGG-S1ベクター / エピトープ / NFκBレポーター遺伝子 / 大腸菌発現系 / 融合蛋白 / pET32ベクター / 神経細胞 / タンパク質の変性 / コア領域 / 小胞体 / 芳香族アミノ酸 / 遺伝子変異 / アポトーシス / ネクローシス / 線維形成のメカニズム / 線維形成コア領域 / アミロイドーシス / ヒトリゾチーム変異体 / 細胞毒性 / トリプトファン62 / コアペプチド / アミロイド線維 / リゾチーム / 構造変調 / 構造相転移 / 比熱 / 動的立体構造特性 / 協同的分子運動 / 生体高分子 / ACカロリーメーター / 比熱測定 Less

Analysis on molecular mechanism for cold adapted glucokinase from psychrophillic bacteria
- Principal Investigator
  
  Horitani Masaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Saga University
Analysis of amyloid fibril formation mechanism and cell toxicity of lysozyme
- Principal Investigator
  
  SUGIMOTO Yasushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Kagoshima University
Structural and Functional Analysis of the MD-2 protein
- Principal Investigator
  
  KIMOTO Masao
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Saga University
Structural evolution and molecular mechanism of cold-active enzymes from Antarctic psychrophilesPrincipal Investigator
- Principal Investigator
  
  WATANABE Keiichi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Saga University
ACカロリメーター比熱測定による生体高分子の協同的立体構造変調の研究
- Principal Investigator
  
  日高昌則
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  物性一般(含基礎論)
- Research Institution
  Kyushu University
Structural Evolution of Enzymes from Antarctic Psychrotrophs and Molecular Mechanism for Their Higher Activities at Low TemperaturesPrincipal Investigator
- Principal Investigator
  
  WATANABE Kenichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Saga University
南極産魚類及び細菌由来酵素の構造と低温適応機構Principal Investigator
- Principal Investigator
  
  渡邊啓一 (渡邉啓一)
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Saga University
Mechanism of recognition of ribosomal substrate by site-specific RNA N-glycosidasesPrincipal Investigator
- Principal Investigator
  
  WATANABE Keiichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Saga University
ヒマ及びヘチマ種子リボソーム不活化蛋白質の活性部位構造ならびに抗ウイルス作用機構Principal Investigator
- Principal Investigator
  
  渡邉啓一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Saga University
ヒマ及びヘチマ種子リボソーム不活化蛋白質のrRNA認識部位の構造に関する研究Principal Investigator
- Principal Investigator
  
  渡邉啓一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Saga University
植物由来リボソーム不活化蛋白質のrRNA認識部位の構造に関する研究Principal Investigator
- Principal Investigator
  
  渡邉啓一
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Saga University
ヒマ及びトウアズキ種子リボソーム不活化蛋白質の活性部位構造に関する研究Principal Investigator
- Principal Investigator
  
  渡邉啓一
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Kyushu University
植物起源の蛋白合成阻害活性蛋白質(PSI)の活性部位構造に関する研究Principal Investigator
- Principal Investigator
  
  渡邉啓一
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Kyushu University

All 2021 2020 2019 2018 2013 2012 Other

All Journal Article Presentation

[Journal Article] X-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy Reveal Active Site Rearrangement of Cold-Adapted Inorganic Pyrophosphatase2020
- Author(s)
  Horitani Masaki、Kusubayashi Kazuki、Oshima Kyoka、Yato Akane、Sugimoto Hiroshi、Watanabe Keiichi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-020-61217-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02412
[Journal Article] Analysis of core region from egg white lysozyme forming amyloid fibrils2013
- Author(s)
  Tokunaga Y, Sakakibara Y, Kamada Y, Watanabe K, Sugimoto Y.
- Journal Title
  
  Int J Biol Sci
  
  Volume: 9 Pages: 219-27
- Data Source
  KAKENHI-PROJECT-22580336
[Journal Article] Analysis of core region from egg white lysozyme forming amyloid fibrils.2013
- Author(s)
  Tokunaga Y, Sakakibara Y, Kamada Y, Watanabe K, Sugimoto Y.
- Journal Title
  
  International Journal of Biological Sciences
  
  Volume: 9 Issue: 2 Pages: 219-227
- DOI
  10.7150/ijbs.5380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580336
[Presentation] Analysis on Cold Adaptation Mechanism of Metalloenzyme by X-ray Crystallography and EPR Spectroscopy Combined with Rapid Freeze-Quench2021
- Author(s)
  Masaki Horitani, Yuri Kasu, Hiroshi Sugimoto, Keiichi Watanabe
- Organizer
  22nd International Society of Magnetic Resonance
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] 急速凍結XAFS法による低温適応無機ピロフォスファターゼの温度特性機構の解明2021
- Author(s)
  丸岡　早紀, 馬込　栄輔, 瀬戸山　寛之, 河本　正秀, 堀谷　正樹, 渡邉　啓一
- Organizer
  第24回XAFS討論会
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] 急速凍結EPR法およびX線結晶構造解析法による好冷細菌由来無機ピロフォスファターゼの低温適応機構の解明2021
- Author(s)
  堀谷　正樹, 杉本　宏, 渡邉　啓一
- Organizer
  第47回生体分子討論会
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] X-ray Crystallography and Site-Directed Spin-Labeling ESR Reveal Cold Adaptation and High Thermal Stability Mechanisms of Cold-Adapted Glucokinase2021
- Author(s)
  Akane Yato, Rio Asaka, Hiroshi Sugimoto, Keiichi Watanabe, Masaki Horitani
- Organizer
  22nd International Society of Magnetic Resonance
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] 動的・静的構造解析による南極産好冷細菌由来グルコキナーゼの低温適応・高熱安定性機構の解明2021
- Author(s)
  矢垰　紅音, 浅香　里緒, 杉本　宏, 渡邉　啓一, 堀谷　正樹
- Organizer
  第47回生体分子討論会
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] EPR Spectroscopy Reveals the Active Site Rearrangement of Di-Mn2+ Center by Substrate Binding in Inorganic Pyrophosphatase from Shewanella sp. AS-112019
- Author(s)
  Masaki Horitani, Hiroshi Sugimoto, Keiichi Watanabe
- Organizer
  Awaji Island Conference on Electron Spin Science & Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] 好冷細菌由来無機ピロフォスファターゼの低温適応機構2019
- Author(s)
  堀谷　正樹, 楠林　和貴, 大嶋　杏佳, 杉本　宏, 渡邉　啓一
- Organizer
  第58回NMR討論会・SEST2019連合大会
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] 好冷細菌由来グルコキナーゼの低温適応・高熱安定性機構の解明2019
- Author(s)
  矢垰　紅音, 浅香　里緒, 渡邊　啓一, 堀谷　正樹
- Organizer
  日本生体エネルギー研究会　第45回討論会
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] 好冷細菌由来無機ピロフォスファターゼの低温適応機構・熱安定性機構2019
- Author(s)
  堀谷　正樹, 杉本　宏, 渡邊　啓一
- Organizer
  日本生体エネルギー研究会　第45回討論会
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] Cold Adaption Inorganic Pyrophosphatase from Shewanella sp. AS-11 was Investigated the Reaction Mechanism by X-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy2019
- Author(s)
  Masaki Horitani, Hiroshi Sugimoto, Keiichi Watanabe
- Organizer
  International Congress on Pure & Applied Chemistry (ICPAC) Yangon 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] Structural Analysis on di-Mn ion site for Shewanella Inorganic Pyrophosphatase by EPR2018
- Author(s)
  堀谷　正樹、榊原　由季、渡邉　啓一
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] 低温適応酵素グルコキナーゼの低温適応機構の解明2018
- Author(s)
  加藤　侑希、林　芙由子、渡邉　啓一、堀谷　正樹
- Organizer
  第42回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Data Source
  KAKENHI-PROJECT-18H02412
[Presentation] リゾチームのアミロイド線維形成コアペプチドの解析2012
- Author(s)
  徳永雄平、清川由樹、釜田佳季、渡邉啓一、杉元康志
- Organizer
  日本ペプチド学会
- Data Source
  KAKENHI-PROJECT-22580336
[Presentation] リゾチームのアミロイド線維形成機構の解明2012
- Author(s)
  徳永雄平、渡邉啓一、杉元康志
- Organizer
  日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-22580336
[Presentation] 胚発生における卵白リゾチームの構造変化2012
- Author(s)
  杉元康志、清川由樹、釜田佳季、渡邉啓一
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-22580336
[Presentation] リゾチームのアミロイド線維形成コアペプチドの解析
- Author(s)
  徳永雄平、清川由樹、釜田佳季、渡邉啓一、杉元康志
- Organizer
  日本ペプチド学会
- Place of Presentation
  鹿児島県民交流センター
- Data Source
  KAKENHI-PROJECT-22580336
[Presentation] 胚発生における卵白リゾチームの構造変化
- Author(s)
  杉元康志、清川由樹、釜田佳季、渡邉啓一
- Organizer
  日本生化学会
- Place of Presentation
  福岡マリンメッセ
- Data Source
  KAKENHI-PROJECT-22580336
[Presentation] リゾチームのアミロイド線維形成機構の解明
- Author(s)
  徳永雄平、渡邉啓一、杉元康志
- Organizer
  日本蛋白質科学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-22580336

1. MOTOSHIMA Hiroyuki (20312275)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. SUGIMOTO Yasushi (10100736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. MATSUMOTO Mitsuharu (30157383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KUSAKABE Takahiro (30253595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KIMOTO Masao (40153225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUKUDOME Kenji (50284625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TSUNEYOSHI Naoko (80336114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Horitani Masaki (80532134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
9. 日高昌則 (50037298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山田秀徳 (80037613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 杉山正明 (10253395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 前田米蔵 (30037262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Keiichi Watanabe 渡邉 啓一

渡邉 啓一 ワタナベ ケイイチ

WATANABE Keiichi 渡邉 啓一

WATANABE Kenichi 渡邉 啓一

渡邊 啓一 ワタナベ ケイイチ

渡辺 啓一 ワタナベ ケンイチ

Research Projects

Research Products

Co-Researchers

Analysis on molecular mechanism for cold adapted glucokinase from psychrophillic bacteria

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of amyloid fibril formation mechanism and cell toxicity of lysozyme

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural and Functional Analysis of the MD-2 protein

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural evolution and molecular mechanism of cold-active enzymes from Antarctic psychrophilesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ACカロリメーター比熱測定による生体高分子の協同的立体構造変調の研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural Evolution of Enzymes from Antarctic Psychrotrophs and Molecular Mechanism for Their Higher Activities at Low TemperaturesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

南極産魚類及び細菌由来酵素の構造と低温適応機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of recognition of ribosomal substrate by site-specific RNA N-glycosidasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒマ及びヘチマ種子リボソーム不活化蛋白質の活性部位構造ならびに抗ウイルス作用機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒマ及びヘチマ種子リボソーム不活化蛋白質のrRNA認識部位の構造に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

植物由来リボソーム不活化蛋白質のrRNA認識部位の構造に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒマ及びトウアズキ種子リボソーム不活化蛋白質の活性部位構造に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Keiichi Watanabe 渡邉啓一

渡邉啓一ワタナベケイイチ

WATANABE Keiichi 渡邉啓一

WATANABE Kenichi 渡邉啓一

渡邊啓一ワタナベケイイチ

渡辺啓一ワタナベケンイチ

[Presentation] リゾチームのアミロイド線維形成コアペプチドの解析2012