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IWASE Hirotaka  岩瀬 弘敬

ORCIDConnect your ORCID iD *help
… Alternative Names

岩瀬 広敬  イワセ ヒロタカ

岩瀬 弘敬  イワセ ヒロタカ

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Researcher Number 40211065
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2014 – 2017: 熊本大学, 大学院生命科学研究部(医), 教授
2012 – 2015: 熊本大学, その他の研究科, 教授
2013 – 2014: 熊本大学, 大学院生命科学研究部, 教授
2011 – 2013: 熊本大学, 生命科学研究部, 教授
2009 – 2011: 熊本大学, 大学院・生命科学研究部, 教授 … More
2008: Kumamoto University, 医学薬学研究部, 教授
2007 – 2008: Kumamoto University, Faculty of Medical and Pharmaceutical Sciences, Professor
2006: 熊本大学, 大学院医学薬学研究部, 教授
2005: Kumamoto University, Faculty of Medical and Pharmaceutical Sciences, Professor, 医学薬学研究室, 教授
2005: 熊本大学, 医学薬学研究部, 教授
2002 – 2004: 名古屋市立大学, 大学院・医学研究科, 助教授
2002: Nagoya City University, Graduate School of Medical Sciences, Associate Professor, 医学研究科, 助教授
2000 – 2001: Nagoya City University, Medical School, Associate Professor, 医学部, 助教授
1996 – 1999: 名古屋市立大学, 医学部, 講師
1998: 名古屋市立大学, 医学部, 助教授
1989: 名古屋市立大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General surgery / General surgery
Except Principal Investigator
General surgery / General surgery / Human pathology / Pediatric surgery
Keywords
Principal Investigator
乳癌 / 転写共役因子 / HDAC6 / AIB1 / NCoR1 / ATBF1 / LOH / DCIS / estrogen receptor α / cofactor … More / エストロゲンレセプター / breast cancer / ATBF1-A / ER遺伝子増幅 / HDAC1 / ER遺伝子 / HDAC阻害薬 / 予後予測因子 / 効果予測因子 / 予後予測ツール / 多遺伝子発現 / 予後予測 / 効果予測 / 乳がん / 癌抑制遺伝子 / Breast cancer / Tumor suppressor gene / エストロゲンレセプターα / ホルモン療法 / ホルモン依存性 / cofactors / AIBI1 / endocrine therapy / ホルモン依存性関連遺伝子 / NcoR1 / IGFBP4 / マイクロダイセクション / エクトロゲンレセプター / cDNAカスタムアレイ / hormone related gene / AIB 1 … More
Except Principal Investigator
乳癌 / ING1 / Stat5 / エストロゲンレセプター / breast cancer / 予後因子 / エストロゲン療法 / mutation / 癌抑制遺伝子 / ING1遺伝子 / 分子生物学 / tumor suppressor gene / ヒト乳癌 / エストロゲン・レセプタ- / cDNA / 遺伝子発現 / DNA / mRNA / 幹細胞 / sca-1 / nucleostemin / パラフィン切片 / フローサイトメーター / CD133 / サテライト細胞 / 乳腺外科学 / ユビキチンリガーゼ / Fbw7 / skp2 / トリプルネガティブ乳癌 / Skp2 / 細胞周期 / MACC1 / cMet / 転写因子 / Breast cancer / c-Met / c-Met / Non-coding RNA / ESR1遺伝子 / 内分泌療法 / ホルモン療法 / ホルモン依存性 / 内分泌療法耐性乳癌 / 家族性乳癌 / エストロゲンレセプター遺伝子 / 遺伝子多型 / ERβ / メチレーション / 生殖細胞変異 / BRCA1 / BRCA2 / LOH / familial breast cancer / estrogen receptor gene / polymorphism / ERbeta / methylation / 神経芽腫 / neuroblastoma / estrogen receptor / エストロゲン・レセプターα / beast cancer / estrogen receptor alfa / 分子標的治療 / targeting therapy / チロシンキナーゼレセプター / コラーゲン / 癌細胞 / 間質浸潤(転移) / RNA干渉 / RNA平渉 / Receptor tyrosine kinase / Collagen / Cancer cells / Stromal i.nvasion(M.etastasis) / RNA interference / 転移乳癌 / エストロゲン受容体 / cfDNA / cfDNA / 逐次内分泌療法 Less
  • Research Projects

    (19 results)
  • Research Products

    (63 results)
  • Co-Researchers

    (22 People)
  •  Mechanism analysis of estrogen addition therapy for metastatic breast cancer

    • Principal Investigator
      Murakami Keiichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  Detection for predictive factors of estrogen addition and depletion therapy in endocrine therapy-resistant breast cancer

    • Principal Investigator
      Omoto Yoko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  内分泌療法耐性乳癌におけるESR1遺伝子制御の解析とエストロゲン作用薬の治療応用

    • Principal Investigator
      冨田 さおり
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  The role of MACC1 in breast cancer

    • Principal Investigator
      YAMAMOTO YUTAKA
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  Development of quantitative evaluation tool using multigene expression to predict efficacy of endocrine therapy for breast cancerPrincipal Investigator

    • Principal Investigator
      IWASE Hirotaka
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  Study for mechanism of cell cycle regulation by ubiquitin ligase in triple-negative breast cancer

    • Principal Investigator
      YAMAMOTO Yutaka
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  The study on the sensitization of transcriptional modulator to endocrine therapy for breast cancerPrincipal Investigator

    • Principal Investigator
      IWASE Hirotaka
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  癌幹細胞の病理組織切片における同定と臨床病理学

    • Principal Investigator
      伊藤 隆明
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Kumamoto University
  •  Analysis of negative regulation of EMT by receptor tyrosine kinase, DDR1

    • Principal Investigator
      KAMOHARA Hidenobu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  The role of Stat5 for targeting therapy and chemoprevention in breast cancer

    • Principal Investigator
      YAMASHITA Hiroko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      NAGOYA CITY UNIVERSITY
  •  Clinicopathological and Functional Analysis of Hormone Related Gene in Breast CancerPrincipal Investigator

    • Principal Investigator
      IWASE Hirotaka
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Nagoya City University
  •  The role of co-factor of estrogen receptor alfa in breast cancer cells

    • Principal Investigator
      TOYAMA Tatsuya
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Aichi Cancer Center Research Institute
      Nagoya City University
  •  Analysis of role of Stat5 in breast cancer

    • Principal Investigator
      YAMASHITA Hiroko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya City University
  •  Analysis of the candidate tumor suppressor ING1 gene in breast cancer.

    • Principal Investigator
      TOYAMA Tatsuya
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya City University
  •  Analysis of the candidate tumor suppressor ING1 gene in neuroblastoma.

    • Principal Investigator
      KONDO Satoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatric surgery
    • Research Institution
      Nagoya City University
  •  Analysis of the Estrogen Receptor α cofactors with reference to Hormone Dependency of Breast CancerPrincipal Investigator

    • Principal Investigator
      IWASE Hirotaka
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      NAGOYA CITY UNIVERSITY
  •  Role of ATBF1 gene in carcinogenesis and progression in breast cancerPrincipal Investigator

    • Principal Investigator
      IWASE Hirotaka
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      NAGOYA CITY UNIVERSITY
  •  Polymorphisms of the estrogen receptor gene in familial breast cancer

    • Principal Investigator
      KOBAYASHI Shunzo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Nagoya City University
  •  乳癌症例におけるエストロゲン・レセプタ-遺伝子発現の解析

    • Principal Investigator
      KOBAYASHI Shunzo
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya City University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] Reproductive Oncology2007

    • Author(s)
      Iwase H, Yamamoto Y, Zhang Z
    • Total Pages
      14
    • Publisher
      Estrogen receptor structure and function in breast cancer pathogenesis.
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Book] Reproductive Oncol2007

    • Author(s)
      Iwase H, Yamamoto Y, Zhang Z
    • Publisher
      Estrogen receptor structure and function in breast cancer pathogenesis. Editor Fujimoto J
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Journal Article] Clinical significance of plasma cell-free DNA mutations in PIK3CA, AKT1, and ESR1 gene according to treatment lines in ER-positive breast cancer2018

    • Author(s)
      Takeshita Takashi、Yamamoto Yutaka、Yamamoto-Ibusuki Mutsuko、Tomiguchi Mai、Sueta Aiko、Murakami Keiichi、Iwase Hirotaka
    • Journal Title

      Molecular Cancer

      Volume: 17 Pages: 67-67

    • DOI

      10.1186/s12943-018-0808-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10057, KAKENHI-PROJECT-17K16511
  • [Journal Article] Analysis of <i>ESR1</i> and <i>PIK3CA</i> mutations in plasma cell-free DNA from ER-positive breast cancer patients2017

    • Author(s)
      Takeshita Takashi、Yamamoto Yutaka、Yamamoto-Ibusuki Mutsuko、Tomiguchi Mai、Sueta Aiko、Murakami Keiichi、Omoto Yoko、Iwase Hirotaka
    • Journal Title

      Oncotarget

      Volume: 8 Pages: 25-28

    • DOI

      10.18632/oncotarget.18479

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16511, KAKENHI-PROJECT-15K10057
  • [Journal Article] Prevalence of ESR1 E380Q mutation in tumor tissue and plasma from Japanese breast cancer patients2017

    • Author(s)
      Takeshita Takashi、Yamamoto Yutaka、Yamamoto-Ibusuki Mutsuko、Sueta Aiko、Tomiguchi Mai、Murakami Keiichi、Omoto Yoko、Iwase Hirotaka
    • Journal Title

      BMC Cancer

      Volume: 17 Pages: 11-15

    • DOI

      10.1186/s12885-017-3779-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16511, KAKENHI-PROJECT-15K10057
  • [Journal Article] Comparison of ESR1 Mutations in Tumor Tissue and Matched Plasma Samples from Metastatic Breast Cancer Patients2017

    • Author(s)
      Takeshita Takashi、Yamamoto Yutaka、Yamamoto-Ibusuki Mutsuko、Tomiguchi Mai、Sueta Aiko、Murakami Keiichi、Omoto Yoko、Iwase Hirotaka
    • Journal Title

      Translational Oncology

      Volume: 10 Pages: 766-771

    • DOI

      10.1016/j.tranon.2017.07.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16511, KAKENHI-PROJECT-15K10057
  • [Journal Article] Clinical significance of monitoring ESR1 mutations in circulating cell-free DNA in estrogen receptor positive breast cancer patients2016

    • Author(s)
      63.Takeshita T, Yamamoto Y, Yamamoto-Ibusuki M, Inao T, Sueta A, Fujiwara S, Omoto Y, Iwase H.
    • Journal Title

      Oncotarget

      Volume: 7 Pages: 32504-18

    • DOI

      10.18632/oncotarget.8839

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461952, KAKENHI-PROJECT-15K21237, KAKENHI-PROJECT-15K10057
  • [Journal Article] Immunohistochemical analysis in ethinylestradiol-treated breast cancers after prior long-term estrogen-deprivation therapy.2015

    • Author(s)
      Omoto Y, Takeshita T, Yamamoto Y, Yamamoto-Ibusuki M, Hayashi M, Sueta A, Fujiwara S, Taguchi T, Iwase H.
    • Journal Title

      Springerplus.

      Volume: 108 Pages: 1-9

    • DOI

      10.1186/s40064-015-0851-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461952
  • [Journal Article] Droplet digital polymerase chain reaction assay for screening of ESR1 mutations in 325 breast cancer specimens.2015

    • Author(s)
      Takeshita T, Yamamoto Y, Yamamoto-Ibusuki M, Inao T, Sueta A, Fujiwara S, Omoto Y, Iwase H.
    • Journal Title

      Transl Res.

      Volume: 166 Pages: 540-553

    • DOI

      10.1016/j.trsl.2015.09.003

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10057, KAKENHI-PROJECT-26461952
  • [Journal Article] Differential role of MACC1 expression and its regulation of the HGF/c‑Met pathway between breast and colorectal cancer2015

    • Author(s)
      Sueta A, Yamamoto Y, Yamamoto-Ibusuki M, Hayashi M, Takeshita T, Yamamoto S, Omoto Y, Iwase A
    • Journal Title

      International Journal of Oncology

      Volume: 46 Pages: 2143-2153

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591909
  • [Journal Article] C6ORF97-ESR1 breast cancer susceptibility locus: influence on progression and survival in breast cancer patients.2015

    • Author(s)
      Yamamoto-Ibusuki M, Yamamoto Y, Fujiwara S, Sueta A, Yamamoto S, Hayashi M, Tomiguchi M, Takeshita T, Iwase H
    • Journal Title

      Eur J Hum Genet

      Volume: Epub Pages: 2143-53

    • DOI

      10.1038/ejhg.2014.219

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591910, KAKENHI-PROJECT-15K21237
  • [Journal Article] Clinical benefit of sequential use of endocrine therapies for metastatic breast cancer.2015

    • Author(s)
      Iwase H, Yamamoto Y.
    • Journal Title

      Int J Clin Oncol

      Volume: Epub

    • DOI

      10.1007/s10147-015-0795-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Journal Article] Clinical significance of estrogen receptor β in breast and prostate cancer from biological aspects.2015

    • Author(s)
      Omoto Y, Iwase H.
    • Journal Title

      Cancer Sci

      Volume: 106 Pages: 337-343

    • DOI

      10.1111/cas.12613

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461952
  • [Journal Article] Clinical Significance of pretherapeutic Ki67 as a predictive parameter for response to neoadjuvant chemotherapy in breast cancer; is it equally useful across tumor subtype2014

    • Author(s)
      Sueta A, Yamamoto Y, Hayashi M, Yamamoto S, Inao T, Ibusuki M, MUrakami M, Iwase H
    • Journal Title

      Surgery

      Volume: Epub

    • DOI

      10.1016/j.surg.2014.01.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Journal Article] Ethinylestradiol is beneficial for postmenopausal patients with heavily pre-treated metastatic breast cancer after prior aromatase inhibitor treatment: a prospective study.2013

    • Author(s)
      Iwase, H., Yamamoto, Y., Yamamoto-Ibusuki, M., Murakami, K.I., Okumura, Y., Tomita, S., Inao, T., Honda, Y., Omoto, Y., and Iyama, K.I.
    • Journal Title

      Br. J. Cancer

      Volume: 109 Pages: 1537-1542

    • DOI

      10.1038/bjc.2013.520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461985
  • [Journal Article] A complehensove analysis of Aurora A; transcript levels are most reliable in association with proliferation and prognosis in breast cancer2013

    • Author(s)
      Yamamoto S, Yamamoto-Ibusuki M, yamamoto Y, Fujiwara S, Iwase H
    • Journal Title

      BMC cancer

      Volume: 13 Pages: 217-217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Journal Article] Comparison of prognostic values between combined immunohistochemical score of estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, Ki-67 and the corresponding gene expression score in breast cancer.2012

    • Author(s)
      Yamamoto-Ibusuki M, Yamamoto Y, Yamamoto S, Fujiwara S, Fu P, Honda Y, Iyama K, Iwase H.
    • Journal Title

      Mod Pathol

      Volume: 26 Pages: 79-86

    • Data Source
      KAKENHI-PROJECT-24591910
  • [Journal Article] High survivin mRNA expression is a predictor of poor prognosis in breast cancer: a comparative study at the mRNA and protein level.2012

    • Author(s)
      Xu C, Yamamoto-Ibusuki M, Yamamoto Y, Yamamoto S, Fujiwara S, Murakami K, Okumura Y, Yamaguchi L, Fujiki Y, Iwase H.
    • Journal Title

      Breast Cancer

      Volume: Epub ahead of print Pages: 20-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Journal Article] Association of ErbB1-4 expression in invasive breast cancer with clinicopathological characteristics and prognosis.2012

    • Author(s)
      Fujiwara S, Ibusuki M, Yamamoto S, Yamamoto Y, Iwase H.
    • Journal Title

      Breast Cancer.

      Volume: Epub ahead of print Pages: 20-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Journal Article] Reduced expression of ubiquitin ligase FBXW7 mRNA is associated with poor prognosis in breast cancer patients2011

    • Author(s)
      Ibusuki M, Yamamoto Y, Shinriki S, Ando Y, Iwase H
    • Journal Title

      Cancer Sci

      Volume: 102(2) Pages: 439-45

    • NAID

      10029290404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591671
  • [Journal Article] Clinicopathological features and treatment strategy for triple-negative breast cancer.2010

    • Author(s)
      Yamamoto Y, Iwase H
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 15 Pages: 341-351

    • NAID

      10026601200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591671
  • [Journal Article] Clinicopathological features and treatment strategy for triple-negative breast cancer2010

    • Author(s)
      Yamamoto Y, Iwase H
    • Journal Title

      Int J Clin Oncol

      Volume: 15(4) Pages: 341-51

    • NAID

      10026601200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591671
  • [Journal Article] Clinical significance of basal-like subtype in triple-negative breast cancer2009

    • Author(s)
      Yamamoto Y, Ibusuki M, Iwase H, et al
    • Journal Title

      Breast Cancer VOL.16

      Pages: 260-270

    • NAID

      10027254696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591671
  • [Journal Article] Estrogen receptor aloha gene ESR1 amplification may predict endocrine therapy responsiveness in breast cancer patients2009

    • Author(s)
      Tomita S, Zhang Z, Nakano M, Ibusuki M, Kawasoe T, Yamamoto Y, Iwase H
    • Journal Title

      Cancer Sci 100

      Pages: 1012-1017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Journal Article] Safety profiles of aromatase inhibitors and selective estrogen-receptor modulators in the treatment of early breast cancer2008

    • Author(s)
      Yamamoto Y, Iwase H
    • Journal Title

      Int J Clin Oncol 13

      Pages: 384-394

    • NAID

      10023919405

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Journal Article] Identification of biomarkers in ductal carcinoma in situ of the breast with microinvasion2008

    • Author(s)
      Okumura, Yamamoto Y, Zhang Z, Toyama T, Kawasoe T, Ibusuki M, Honda Y, Iyama K, Yamashita H, Iwase H
    • Journal Title

      BMC cancer E-pub

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Journal Article] 内分泌療法の効果予測-遺伝子プロファイリングから-2007

    • Author(s)
      岩瀬弘敬、山本豊
    • Journal Title

      日本臨床 65

      Pages: 549-554

    • Data Source
      KAKENHI-PROJECT-19591513
  • [Journal Article] Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer.2007

    • Author(s)
      Yamamoto Y, Ibusuki M, Iwase H
    • Journal Title

      Breast Cancer Res Treat E-pub

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Journal Article] ATBF1-a messenger RNA expression is correlated with better prognosis in breast cancer.2005

    • Author(s)
      Zhang Z, Iwase H, et al.
    • Journal Title

      Clin Cancer Res 11(1)

      Pages: 193-198

    • Data Source
      KAKENHI-PROJECT-14370362
  • [Journal Article] ATBF1-A messenger RNA is correlated with better prognosis in breast cancer2005

    • Author(s)
      Z Zhang, H Iwase et al.
    • Journal Title

      Clinical Cancer Research 11

      Pages: 193-198

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370362
  • [Journal Article] ATBF1-A messenger RNA is correlated with better prognosis in breast cancer2005

    • Author(s)
      Z Zhang, H Iwase et al.
    • Journal Title

      Clin Cancer Res 11

      Pages: 193-198

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370362
  • [Journal Article] HDAC6 expression is correlated with better survival in breast cancer.2004

    • Author(s)
      Zhang Z, Iwase H, et al.
    • Journal Title

      Clin Cancer Res 10(20)

      Pages: 6962-6968

    • Data Source
      KAKENHI-PROJECT-14370362
  • [Journal Article] HDAC6 expression is correlated with better survival in breast cancer.2004

    • Author(s)
      Z Zhang, H Iwase, et al.
    • Journal Title

      Clinical Cancer Research 10

      Pages: 6962-6968

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370362
  • [Journal Article] HDAC6 expression is correlated with better survival in breast cancer2004

    • Author(s)
      Z Zhang, H Iwase, et al.
    • Journal Title

      Clin Cancer Res 10

      Pages: 6962-6968

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370362
  • [Journal Article] Clinical significance of AIB1 expression in human breast cancer.2003

    • Author(s)
      H Iwase, et al.
    • Journal Title

      Breast Cancer Research and Treatment 80

      Pages: 339-345

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370362
  • [Journal Article] Clinical significance od AIB1 expression in breast cancer.2003

    • Author(s)
      Iwase H, Omoto Y, et al.
    • Journal Title

      Breast Cancer Res Treat 80

      Pages: 339-345

    • Data Source
      KAKENHI-PROJECT-14370362
  • [Journal Article] Clinical significance of AIB 1 expression in human breast cancer2003

    • Author(s)
      H Iwase, et al.
    • Journal Title

      Breast Cancer Res and Treat 80

      Pages: 339-345

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370362
  • [Presentation] Treatment strategy for metastatic breast cancer with estrogen receptor-positive tumor.2017

    • Author(s)
      Hirotaka Iwase
    • Organizer
      第15回日本臨床腫瘍学会学術集会 29th July, 2016 Kobe, Japan.
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K10057
  • [Presentation] Incidence and clinical relevance of&nbsp;ESR1 mutations&nbsp;in estrogen receptor positive breast cancer patients2017

    • Author(s)
      1.Takeshita T, Tomiguchi M, Sueta A, Murakami K, Yamamoto-Ibusuki M, Yamamoto Y, Iwase H
    • Organizer
      第15回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K10057
  • [Presentation] ER陽性乳癌患者におけるESR1 mutationのスポットおよび連続検索の臨床学的意義2017

    • Author(s)
      1.Takeshita T, Tomiguchi M, Sueta A, Murakami K, Yamamoto-Ibusuki M, Yamamoto Y, Iwase H
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K10057
  • [Presentation] 閉経後進行乳癌におけるエストロゲン枯渇療法と付加療法との交代投与法の経験2017

    • Author(s)
      岩瀬弘敬, 指宿睦子, 末田愛子, 竹下卓志, 富口麻衣, 山本 豊, 村上敬一
    • Organizer
      第18回ホルモンと癌研究会
    • Data Source
      KAKENHI-PROJECT-15K10057
  • [Presentation] 乳がんホルモン療法耐性における分子標的治療の役割2017

    • Author(s)
      岩瀬弘敬
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K10057
  • [Presentation] Clinical significance of sequential measurement of ESR1 mutations in plasma cell-free DNA in metastatic breast cancer.2016

    • Author(s)
      Hirotaka Iwase.
    • Organizer
      7th Seoul Breast Cancer Symposium
    • Place of Presentation
      Seoul, South Korea
    • Year and Date
      2016-09-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461952
  • [Presentation] Clinical significance of sequential measurements of ESR1 mutations in plasma cell-free DNA in estrogen receptor positive recurrent metastatic breast cancer patients2016

    • Author(s)
      Takeshita T, Yamamoto Y, Yamamoto-Ibusuki M, Sueta A, Tomiguchi M and Iwase H
    • Organizer
      The 39th San Antonio Breast Cancer Symposium
    • Place of Presentation
      S案Antonio, TX USA
    • Year and Date
      2016-12-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10057
  • [Presentation] Clinical significance of sequential measurements of ESR1 mutations in plasma cell-free DNA in estrogen receptor positive recurrent metastatic breast cancer patients.2016

    • Author(s)
      Takeshita T, Yamamoto Y, Yamamoto-Ibusuki M, Sueta A, Tomiguchi M and Iwase H.
    • Organizer
      The 39th San Antonio Breast Cancer Symposium
    • Place of Presentation
      San Antonio, TX, USA
    • Year and Date
      2016-12-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461952
  • [Presentation] Clinical significance of ESR1 mutations using droplet digital polymerase chain reaction assay in 325 breast cancer samples.2015

    • Author(s)
      Takeshita T, Yamamoto Y, Yamamoto-Ibusuki M, Inao T, Sueta A, Fujiwara S, Iwase H
    • Organizer
      The 38th San Antonio Breast Cancer Symposium
    • Place of Presentation
      San Antonio, TX
    • Year and Date
      2015-12-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461952
  • [Presentation] ESR1 gene alterations in the metastatic breast cancer with resistance to aromatase inhibitor.2015

    • Author(s)
      Iwase H, Takeshita T, Yamamoto-Ibusuki M, Inao T, Sueta A, Fujiwara S, Yamamoto Y
    • Organizer
      Advances in Breast Cancer Research
    • Place of Presentation
      Bellevue, Washington
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10057
  • [Presentation] Clinical significance of ESR1 mutations by cell-free DNA in recurrent/metastatic breast cancer.2015

    • Author(s)
      Takeshita T, Yamamoto Y, Yamamoto-Ibusuki M, Inao T, Sueta A, Fujiwara S, Iwase H
    • Organizer
      Advances in Breast Cancer Research
    • Place of Presentation
      Bellevue, Washington
    • Year and Date
      2015-10-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461952
  • [Presentation] ESR1 gene alterations in the metastatic breast cancer with resistance to aromatase inhibitor.2015

    • Author(s)
      Iwase H, Takeshita T, Yamamoto-Ibusuki M, Inao T, Sueta A, Fujiwara S, Yamamoto Y
    • Organizer
      Advances in Breast Cancer Research
    • Place of Presentation
      Bellevue, Washington
    • Year and Date
      2015-10-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461952
  • [Presentation] 長期にアロマターゼ阻害薬を投与したER陽性再発乳癌患者におけるEE2 治療前後の遺伝子発現の免染での検討2014

    • Author(s)
      大本陽子、竹下卓志、指宿睦子、藤原沙織、末田愛子、林 光博、山本聡子、稲尾瞳子、奥村恭博、村上敬一、山本 豊、岩瀬弘敬
    • Organizer
      第22回日本乳癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-10
    • Data Source
      KAKENHI-PROJECT-26461952
  • [Presentation] Luminal型乳癌における包括的予後スコア創出の試みとその有用性2012

    • Author(s)
      指宿睦子、山本 豊、山本聡子、藤原沙織、村上敬一、岩瀬弘敬
    • Organizer
      第20回日本乳癌学会学術総会
    • Place of Presentation
      熊本 ホテル日航熊本
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Presentation] Tha advantage of copy number variation assay of ERBB2 using FFPE specimens: a comprehensive study2012

    • Author(s)
      Ibusuki M,Yamamoto Y, Yamamoto S, Fujiwara S, Iwase H
    • Organizer
      The 20th Annual Meeting of The Japanese Breast Cancer Society
    • Place of Presentation
      Kumamoto,Japan,Hotel Nikko Kumaoto
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Presentation] Redu ced expression of ubiquitin ligase FB XW7 mRNA is associated with poor prog nosis in breast cancer patients2011

    • Author(s)
      Ibusuki M, Yamamoto Y, Iwase H
    • Organizer
      Adva nces in Breast Cancer Research
    • Place of Presentation
      サンフランシスコ、米国
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PROJECT-21591671
  • [Presentation] Reduced expression of ubiquitin ligase FBXW7 mRNA is associated with poor prognosis in breast cancer patients2011

    • Author(s)
      指宿睦子、山本豊、岩瀬弘敬
    • Organizer
      Advances in Breast Cancer Research
    • Place of Presentation
      米国サンフランシスコ
    • Data Source
      KAKENHI-PROJECT-21591671
  • [Presentation] NCoR1蛋白発現は進行再発乳癌における内分泌療法の効果と関連する2008

    • Author(s)
      富田さおり、山本豊、岩瀬弘敬
    • Organizer
      日本乳癌学会
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-26
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Presentation] 乳癌におけるErα遺伝子増幅の検討2008

    • Author(s)
      富田さおり、山本豊、岩瀬弘敬
    • Organizer
      第9回ホルモンと癌研究会
    • Place of Presentation
      岐阜
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Presentation] エストロゲンレセプターとLuminal乳癌2008

    • Author(s)
      山下啓子、岩瀬弘敬
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-23
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Presentation] 乳癌ホルモン療法の効果予測因子の解析2008

    • Author(s)
      山下啓子、岩瀬弘敬
    • Organizer
      日本癌治療学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-31
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Presentation] エストロゲンレセプターの分子機構解析と乳癌内分泌療法2007

    • Author(s)
      岩瀬 弘敬
    • Organizer
      第19回日本内分泌外科学会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-05-31
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Presentation] エストロゲンレセプターの分子機構解析と乳癌内分泌療法2007

    • Author(s)
      岩瀬弘敬
    • Organizer
      第18回日本内分泌外科学会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-05-31
    • Data Source
      KAKENHI-PROJECT-19591513
  • [Presentation] Ethinylestradiol treatment downregulates ER and upregulates PgR; Immunohistochemical analysis in postmenopausal breast cancer tissues after prior long-term estrogen-deprivation therapy

    • Author(s)
      Hirotaka Iwase, Yoko Omoto, Takeshi Takeshita, Mutsuko Yamamoto-Ibusuki, Mitsuhiro Hayashi, Aiko Sueta, Saori Fujiwara, Yutaka Yamamoto
    • Organizer
      23rd San Antonio Breast Cancer Syposium
    • Place of Presentation
      San Antonio
    • Year and Date
      2014-12-10 – 2014-12-13
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Presentation] Gene expression analysis in ethinylestradiol-treated breast cancers following long-term estrogen-deprivation therapy

    • Author(s)
      Hirotaka Iwase, Takashi Takeshita, Aiko Sueta, Mai Tomiguchi,Yutaka Yamamoto
    • Organizer
      第76回 日本癌学会学術総会
    • Place of Presentation
      横浜、English Oral Session: Breast Cancer
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24591910
  • [Presentation] A role of MACC1 expression and its regulation of the HGF/c-Met pathway in breast cancer

    • Author(s)
      Aiko S, Yamamoto Y, Hayashi M, Takeshita T, Yamamoto-Ibusuki M, Iwase H
    • Organizer
      37th San Antonio Breast Cancer symposium
    • Place of Presentation
      San Antonio, TX, USA
    • Year and Date
      2014-12-06 – 2014-12-13
    • Data Source
      KAKENHI-PROJECT-24591909
  • 1.  TOYAMA Tatsuya (30315882)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  YAMAMOTO Yutaka (20398217)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 36 results
  • 3.  IBUSUKI Mutsuko (30448526)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 16 results
  • 4.  YAMASHITA Hiroko (70332947)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  KOBAYASHI Shunzo (50080057)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Omoto Yoko (80642561)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  KONDO Satoshi (50234935)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  HAMAGUCHI Maho (70381845)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MITA Keiko (70381895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KAMOHARA Hidenobu (90398222)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  BABA Hideo (20240905)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  IYAMA Kenichi (10040536)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ISHIKO Takatoshi (00343351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Murakami Keiichi (20530124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 15.  伊藤 隆明 (70168392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  藤本 哲広 (70359818)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  宇高 直子 (90285106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  市村 隆也 (40423652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  野守 裕明 (90146613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  冨田 さおり (50646122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  田口 哲也 (80243260)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  竹下 卓志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results

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