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OKUBO KOUSAKU  大久保 公策

ORCIDConnect your ORCID iD *help
… Alternative Names

大久保 公策  オオクボ コウサク

OKUBO Kousaku  大久保 公策

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Researcher Number 40233069
Other IDs
External Links
Affiliation (Current) 2025: 国立遺伝学研究所, 情報研究系, 教授
Affiliation (based on the past Project Information) *help 2015: 国立遺伝学研究所, 生命情報研究センター, 教授
2003 – 2009: 国立遺伝学研究所, 生命情報・DDBJ研究センター, 教授
2007: National Institute of Genetics, Center for Information Biology and DNA Data Bank of Japan, Professor
2002: 九州大学, 生体防御医学研究所, 教授
1994 – 2001: 大阪大学, 細胞生体工学センター, 助教授 … More
1997 – 1998: 大阪大学, 細胞工学センター, 助教授
1995: 大阪大学, 医学部, 助教授
1991: 大阪大学, 細胞工学センター, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences
Except Principal Investigator
Ophthalmology / Kidney internal medicine / Orthopaedic surgery / Intelligent informatics / Applied genomics / Evolutionary biology / Otorhinolaryngology / Molecular biology / 系統・分類
Keywords
Principal Investigator
遺伝子発現 / 生体生命情報学 / 遺伝子 / マイクロアレイ / 情報工学 / ゲノム / マウス / Expresed Sequence Tags / Comparative genomics / Gene Expression … More / Natural language processing / BioNLP / Automatic Indexing / Information retrieval / 塩基配列決定 / オントロジー / 知識発見 / 乳がん / アレルギー性皮膚炎 / 乾癬 / 病理組織 / 遺伝子発現プロフィール / 発現プロファイル / iAFLP法 / 疾患遺伝子 / 自動索引 / 比較ゲノム / EST / 情報検索 / 自然言語処理 / 神経発生 / 胚発生 / シーケンス / cDNAライブラリ / 発生 / 胚 … More
Except Principal Investigator
gene expression / corneal epithelium / human / ヒト / 角膜上皮 / cDNA library / cDNAライブラリー / DDBJ / マイクロアレイ / laser microdissection / conjunctival epithelium / 結膜上皮 / 特異的な遺伝子 / cDNA解析 / RNAi / C-MET / Tpr / HGF / differential display / 遺伝子 / データベース / in vivo / 遺伝子発現 / cDNA / ゲノム機能解析 / ゲノム構造解析 / 意味解析 / 構文解析 / 脱文脈化 / 単純文化 / Gene Expression Regulation / Cell・Tissue / 発現制御 / 細胞・組織 / data standardization / human genes / evolutionary information / annotation / genome / biological database / International visit / 国際DNAデータバンク実務者会議 / 非タンパク質遺伝子 / チンパンジー染色体 / ヒト発現遺伝子 / イネゲノム / マイクロアレイデータ / Annotation / UniProt / DNA配列データベース / ヒト遺伝子 / アノテーション / 進化情報 / ゲノム / 多国籍 / 国際情報交換 / Stevens-Johnson syndrome / microarray / dry eye / disease-related gene / スティーブンス・ジョンソン症候群 / スターブンス・ジョンソン症候群 / スチーブンス・ジョンソン症候群 / 遺伝子発現解析 / ドライアイ / 疾患関連遺伝子 / nephron / database / gene / proteinuria / progressive renal disease / 発現遺伝子データベース / 大規模遺伝子解析 / Nephron / 蛋白尿 / 進行性腎障害 / Cl channel / uroplakin Ib / cathepsin V / specific gene / Clチャンネル / ウロプラキンIb / カテプシンV / cathepsin / keratin 12 / specific genes / cDNA analysis / カテプシン / ケラチン12 / protein-protein interaction / gene disruption / phenotype / expression pattern / full-length cDNA / FST / ディファレンシャルディスプレイ / 枯草菌 / 出芽酵母 / 線虫 / 酵母two-hybrid法 / 遺伝子発現パターン / ATAC-PCR / ボディマップ / 遺伝子発現プロファイル / タンパク間相互作用 / 遺伝子破壊 / 表現型 / 発現パターン / 完全長cDNA / EST / 3'prime cDNA / cholesteatoma / MMP-9 / IL-6 / 3′プライム方向cDNA / c-meb / 3'プライム方向cDNA / 真珠腫 / bone formation / proteins / genes / osteoblast / 骨基質タンパク / 骨芽細胞 / Database / Yeast genome / Analysis of B.subtilis / Human genome / Genome informatics / Functional analysis / Structural analyzes / Genome research / 酵母ゲノム / 枯草菌ゲノム解析 / ヒトゲノム / ゲノム情報解析 / ゲノム研究 / unknown gene / known gene / random sequence / 未知遺伝子 / 既知遺伝子 / ランダムシーケンス / _cDNAライブラリー / 角膜上皮細胞 / 塩基配列決定 / 遺伝的地図 / 物理的地図 / 生物情報科学 / モデル生物 / DNA解析技術 / ヒト・ゲノム / グロビン / オプシン / 恒温動物と変温動物 / コドン使用頻度 / 多細胞生物の起源 / 多細胞モザイク説 / in situ Hybridization / ノーザンブロット / クローニング / 遺伝子情報データベース / 腎ネフロン・セグメント / 新規遺伝子 / 骨形態計測 / サブトラクションハイブリダイゼイション / マーカー / 骨粗鬆症 / mRNA Less
  • Research Projects

    (20 results)
  • Research Products

    (63 results)
  • Co-Researchers

    (54 People)
  •  Simplifying Complicated Sentences for Information Extraction from Text Documents

    • Principal Investigator
      HARA KAZUO
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Intelligent informatics
    • Research Institution
      National Institute of Genetics
  •  Exhaustive Collection of Gene Modules that Changes Functions and Structures of Cells

    • Principal Investigator
      FUJIBUCHI Wataru
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied genomics
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Statistical method to represent biomedical knowledgePrincipal Investigator

    • Principal Investigator
      OKUBO Kousaku
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Genetics
  •  Collection and Investigation into Basic Evolutionary Information by Orrsite Collaboration

    • Principal Investigator
      TATENO Yoshio
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Evolutionary biology
    • Research Institution
      National Institute of Genetics
  •  Development of pathogenesis-analyzing methods-based on gene expression profilesPrincipal Investigator

    • Principal Investigator
      OKUBO Kousaku
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Genetics
      Kyushu University
      Osaka University
  •  Functional analysis and genomic mapping of corneal epithelium-specific genes and detection of disease-related genes among ocular surface disorders.

    • Principal Investigator
      KINOSHITA Shigeru
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The analysis of genes related to the progressive kidney disease using gene expression progiles

    • Principal Investigator
      TAKENAKA Masaru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  Isolation and functional analysis of genes uniquely expressed in human corneal epithelium and conjunctival epithelium

    • Principal Investigator
      KINOSHITA Shigeru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  「多細胞モザイク説:多細胞生物の起源」の検証

    • Principal Investigator
      篠沢 隆雄
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      系統・分類
    • Research Institution
      Gunma University
  •  Functional Genomics

    • Principal Investigator
      KOHARA Yuji
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Institute of Genetics
  •  Isolation and Analysis of unknown genes uniquely expressed in human corneal epithelium.

    • Principal Investigator
      KINISHITA Shigeru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  マウス胚発生過程で特異的に働く遺伝子群の解析Principal Investigator

    • Principal Investigator
      大久保 公策
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  新規な骨粗鬆症マーカーの開発

    • Principal Investigator
      橋本 淳
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Osaka University
  •  ネフロン各部における発現遺伝子のインデックス化によるセグメント特異的遺伝子の同定

    • Principal Investigator
      IMAI Enyu
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  Japan-French Joint Research on Genome

    • Principal Investigator
      MATSUBARA Kenichi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      International Institute for Advanced Studies
      Osaka University
  •  Identification of novel protein molecules produced by osteoblasts

    • Principal Investigator
      TAKAOKA Kunio
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Shinshu University
  •  Specific expression of molecules in the tissues of cholesteatoma otitis media -3'prime cDNA subtraction method analysis-

    • Principal Investigator
      DOI Katsumi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Osaka University
  •  マウス胚発生過程で特異的に働く遺伝子群の解析Principal Investigator

    • Principal Investigator
      大久保 公策
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Gene expression analysis of human corneal and conjunctival epithelium by random cDNA sequencing

    • Principal Investigator
      KINOSHITA Shigeru
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  ヒト・ゲノム解析研究

    • Principal Investigator
      MATSUBARA Kenichi
    • Project Period (FY)
      1991 – 1995
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Osaka University

All 2014 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000

All Journal Article Presentation Book Patent

  • [Book] 「生命科学データベースの現状と課題」2007

    • Author(s)
      大久保公策
    • Total Pages
      5
    • Publisher
      株式会社岩波書店
    • Data Source
      KAKENHI-PROJECT-17017037
  • [Book] 文献知識の計算機による利用がなぜ必要か2005

    • Author(s)
      大久保 公策
    • Publisher
      共立出版株式会社
    • Data Source
      KAKENHI-PROJECT-17017037
  • [Book] ゲノム語とオントロジーという名の形而上学-進化と医学(科学)2004

    • Author(s)
      大久保公策
    • Total Pages
      3
    • Publisher
      岩波書店
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Book] Quantification of Gene Expression in Mouse and Human Renal Proximal Tubules.「Laser Capture Microdissection Methods and Protocols」Methods in Molecular Biology 2932004

    • Author(s)
      Kaimori, J., Takenaka, M., Okubo, K.
    • Total Pages
      12
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-16255006
  • [Book] Introduction to Bioinformatics A Theoretical And Practical Approach2003

    • Author(s)
      Okubo K.
    • Total Pages
      24
    • Publisher
      Humana Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Book] Analysing Gene Expression2002

    • Author(s)
      Okubo K.
    • Total Pages
      5
    • Publisher
      John Wiley&Sons,Inc.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] On theoretical models of gene expression evolution with random genetic drift and natural selection2009

    • Author(s)
      Ogasawara O., Okubo K.
    • Journal Title

      PLoS One. 4(11)

    • Data Source
      KAKENHI-PROJECT-17017037
  • [Journal Article] Exhaustive Search Method of Gene Expression Modules and Its Application to Human Tissue Data2007

    • Author(s)
      Okada, Y., Okubo, K., Horton, P.and Fujibuchi, W.
    • Journal Title

      IAENG International Journal of Computer Science 34

      Pages: 119-126

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18510178
  • [Journal Article] Cornichon-like Protein Facilitates Secretion of HB-EGF and Regulates Proper Development of CranialNerves.2007

    • Author(s)
      Hoshino H, Uchida T, Otsuki T, Kawamoto S, Okubo K, Takeichi M, Chisaka O.
    • Journal Title

      Molecular Biology of the Cell Apr Vol.18

    • Data Source
      KAKENHI-PROJECT-17017037
  • [Journal Article] BodyMap-Xs: anatomical breakdown of 17 million animal ESTs for cross-species comparison of gene expression.2006

    • Author(s)
      Ogasawara O, Otsuji M, Watanabe K, Iizuka T, Tamura T, Hishiki T, Kawamoto S, Okubo K.
    • Journal Title

      Nucleic Acids Res 34

    • Data Source
      KAKENHI-PROJECT-17017037
  • [Journal Article] DDBJ in preparation for overview of research activities behind data submissions.2006

    • Author(s)
      Okubo, K.
    • Journal Title

      Nucleic Acids Res. 34

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] BodyMap-Xs : anatomical breakdown of 17 million animal ESTs for cross-species comparison of gene expression.2006

    • Author(s)
      Ogasawara O., Otsuji M., Watanabe K., Iizuka T., Tamura T., Hishiki T., Kawamoto S., Okubo K.
    • Journal Title

      Nucleic Acids Res. 1;34(Database issue)

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] DDBJ in preparation for overview of research activities behind data submissions.2006

    • Author(s)
      Okubo, K, Sugawara, H, Gojobori, T, Tateno, Y.
    • Journal Title

      Nucleic Acids Res. 34(Database issue)

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] BodyMap-Xs : anatomical breakdown of 17 million animal ESTs for cross-species comparison of gene expression.2006

    • Author(s)
      Ogasawara O, Otsuji M, Watanabe K, Iizuka T, Tamura T, Hishiki T, Kawamoto S, Okubo K.
    • Journal Title

      Nucleic Acids Res. 34

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] DDBJ in preparation for overview of research activities behind data submissions.2006

    • Author(s)
      Okubo K
    • Journal Title

      Nucleic Acids Res. 34(Database issue)

      Pages: 6-9

    • Data Source
      KAKENHI-PROJECT-17017037
  • [Journal Article] DDBJ in preparation for overview of research activities behind data submissions2006

    • Author(s)
      Okubo, K.
    • Journal Title

      Nucleic Acids Res. 34

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] The Human Anatomic Gene Expression Library (H-Angel), the H-Invintegrative display of human gene expression across disparate technologies and platforms.2005

    • Author(s)
      Tanino, M., Debily, M.-A-., Tamura, T., Hishiki, T., Ogasawara, O., Murakawa, K., Kawamoto, S., Itoh K., Watanabe, S., Souza, S.J.d., Imbeaud, S., Graucens, E., Eveno, E., Hilton, P., Sudo, Y., Kelso, J., Ikeo, K., Imanishi, T., Gojobori, T., Auffray, C., Hide, W., Okubo, K.
    • Journal Title

      Nucleic Acids Res. 33

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] DDBJ in collaboration with mass-sequencing teams on annotation.2005

    • Author(s)
      Tateno Y., Saitou N., Okubo K., Sugawara H., Gojobori T.
    • Journal Title

      Nucleic Acids Research 33

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms.2005

    • Author(s)
      Tanino, M., Debily, MA., Tamura, T., Hishiki, T., Ogasawara, O., Murakawa, K., Kawamoto, S., Itoh, K., Watanabe, S., de Souza, SJ., Imbeaud, S., Graudens, E.Eveno, E., Hilton, P., Sudo, Y., Kelso, J., Ikeo, K., Imanishi, T., Gojobori, T., Auffray, C., Hide, W., Okubo, K.
    • Journal Title

      Nucleic Acids Res. 33

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] ポストゲノム時代に高まるバイオ自然言語処理への期待:バイオ自然言語処理最新事情 5.ゲノムデータの機械解釈2005

    • Author(s)
      大久保公策, 日紫喜光良
    • Journal Title

      情報処理 46(480)

      Pages: 137-142

    • NAID

      110002768351

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] ポストゲノム時代に高まるバイオ自然言語処理への期待:バイオ自然言語処理最新事情5.ゲノムデータの機械解釈2005

    • Author(s)
      大久保 公策
    • Journal Title

      情報処理 46・2480

      Pages: 137-142

    • NAID

      110002768351

    • Data Source
      KAKENHI-PROJECT-17017037
  • [Journal Article] Identification of differentially expressed genes in psoriasis using expression profiling approaches.2005

    • Author(s)
      Itoh K, Kawasaki S, Kawamoto S, Seishima M, Chiba H, Michibata H, Wakimoto K, Imai Y, Minesaki Y, Otsuji M, Okubo K.
    • Journal Title

      Exp Dermatol. 14(9)

      Pages: 667-74

    • Data Source
      KAKENHI-PROJECT-17017037
  • [Journal Article] Identification of differentially expressed genes in psoriasis using expression profiling approaches.2005

    • Author(s)
      Itoh K, Kawasaki S, Kawamoto S, Seishima M, Chiba H, Michibata H, Wakimoto K, Imai Y, Minesaki Y, Otsuji M, Okubo K.
    • Journal Title

      Exp Dermatol. 14(9)

      Pages: 667-674

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] Quantification of gene expression in mouse and human renal proximal tubules2005

    • Author(s)
      Kaimori JY, Takenaka M, Okubo K.
    • Journal Title

      Methods Mol Biol. 293

      Pages: 209-19

    • Data Source
      KAKENHI-PROJECT-17017037
  • [Journal Article] The Human Anatomic Gene Expression Library (H-ANGEL)2005

    • Author(s)
      Tanino, M., Debily, MA., Tamura, T., Hishiki, T., Ogasawara, O., Murakawa, K., Kawamoto, S., Itoh, K., Watanabe, S., de Souza, SJ., Imbeaud, S., Graudens, E., Eveno, E., Hilton, P., Sudo, Y., Kelso, J., Ikeo, K., Imanishi, T., Gojobori, T., Auffray, C., Hide, W., Okubo K
    • Journal Title

      Nucleic Acids Res 33

    • Data Source
      KAKENHI-PROJECT-17017037
  • [Journal Article] Indexing anatomical concepts to OMIM Clinical Synopsis using the UMLS Metathesaurus.2004

    • Author(s)
      Hishiki, T., Ogasawara, O., Tsuruoka, Y., Okubo, K.
    • Journal Title

      In Silico Biol. 4

      Pages: 31-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Quantification of Gene Expression in Mouse, Human Renal Proximal Tubules., 「Laser Capture Microdissection Methods and Protocols」 (Grame I. Murray and Stephanie Curran ed.) Methods in Molecular Biology2004

    • Author(s)
      Kaimori, J., Takenaka, M., Okubo, K.
    • Journal Title

      Humana Press 293

      Pages: 209-220

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Identification and characterization of a novel component of the cornified envelope, cornifelin.2004

    • Author(s)
      Michibata, H., Chiba, H., Wakimoto, K., Seishima, M., Kawasaki, S., Okubo, K., Mitsui, H., Torii, H., Imai, Y.
    • Journal Title

      Biochem Biophys Res Commun. 318

      Pages: 803-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Integrative annotation of 21,037 human genes validated by full-Length cDNA clones.2004

    • Author(s)
      Imanishi, T., Itoh, T., Suzuki, Y., O'Donovan, C., Fukuchi, S., Koyanagi, KO., Barrero, RA., Tamura, T., Yamaguchi-Kabata, Y., Tanino, M., Yura, K., Miyazaki, S., Ikeo, K., Homma, K., Kasprzyk, A., Nishikawa, T., Hirakawa, M., Thierry-Mieg, J., Thierry-Mieg, D., Ashurst, J., Jia, L., Nakao, M., Thomas, MA., Mulder, N., Karavidopoulou, Y., Jin, L., Kim, S., Yasuda, T., Lenhard, B., Eveno, E., Suzuki, Y., Yamasaki, C., Takeda, JI., Gough, C., Hilton, P., Fujii, Y., Sakai, H., Tanaka, S., Amid, C., Bellgard, M., Bonaldo, Mde F., Bono, H., Bromberg, SK., Brookes, AJ., Bruford, E., Carninci, P., Chelala, C., Couillault, C., Souza, SJ., Debily, MA., Devignes, MD., Dubchak, I., Endo, T., Estreicher, A., Eyras, E., Fukami-Kobayashi, K., R Gopinath, G., Graudens, E., Hahn, Y., Han, M., Han, ZG., Hanada, K, Hanaoka, H., Harada, E., Hashimoto, K., Hinz, U., Hirai, M., Hishiki, T., Hopkinson, I., Imbeaud, S., Inoko, H., Kanapiri, A., Kaneko, Y., Kasukawa, T., Kelso, J., Kersey, P., Kikuno, R., Kimura, K., Korn, B., Kuryshev, V., Makalowska, I., Makino, T., Mano, S., Mariage-Samson, R., Mashima, J., Matsuda, H., Mewes, HW., Minoshima, S., Nagai, K., Nagasaki, H., Nagata, N., Nigam, R., Ogasawara, O., Ohara, O., Ohtsubo, M., Okada, N., Okido, T., Oota, S., Ota, M., Ota, T., Otsuki, T., Piatier-Tonneau, D., Poustka, A., Ren, SX., Saitou, N., Sakai, K, Sakamoto, S., Sakate, R., Schupp, I., Servant, F., Sherry, S., Shiba, R., Shimizu, N., Shimoyama, M., Simpson, AJ., Soares, B., Steward, C., Suwa, M., Suzuki, M., Takahashi, A., Tamiya, G., Tanaka, H., Taylor, T., Terwilliger, JD., Unneberg, P., Veeramachaneni, V., Watanabe, S., Wilming, L., Yasuda, N., Yoo, HS., Stodolsky, M., Makalowski, W., Go, M., Nakai, K, Takagi, T., Kanehisa, M., Sakaki, Y., Quackenbush, J., Okazaki, Y., Hayashizaki, Y., Hide, W., Chakraborty, R., Nishikawa, K., Sugawara, H., Tateno, Y., Chen, Z., Oishi, M., Tonellato, P., Apweiler, R., Okubo, K., Wagner, L., Wiemann, S., Strausberg, RL., Isogai, T., Auffray, C., Nomura, N., Gojobori, T., Sugano, S.
    • Journal Title

      PLoS Biol. 2

      Pages: 856-75

    • NAID

      120004667172

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Indexing anatomical concepts to OMIM Clinical Synopsis using the UMLS Metathesaurus.2004

    • Author(s)
      Hishiki, T., Ogasawara, O., Tsuruoka, Y., Okubo.K.
    • Journal Title

      In Silico Biology 4

      Pages: 31-54

    • Data Source
      KAKENHI-PROJECT-16255006
  • [Journal Article] Cloning of a gene for a novel epithelium-specific Cytosolic Phospholipase A2,cPLA2delta, induced in Psoriatic Skin.2004

    • Author(s)
      Chiba, H., Michibata, H., Wakimoto, K, Seishima, M., Kawasaki, S., Okubo, K, Mitsui, H., Torii, H., Imai, Y.
    • Journal Title

      J Biol Chem. 279

      Pages: 12890-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Up-regulated gene expression in the conjunctival epithelium of patients with Sjogren's syndorome.2003

    • Author(s)
      Kawasaki S, Kawamoto S, Yokoi N, Connon C, Minesaki Y, Kinoshita S, Okubo K.
    • Journal Title

      Exp Eye Res. 77

      Pages: 17-26

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] A novel diacylglycerol acyltransferase(DGAT2)is decreased in human psoriatic skin and increased in diabetic mice.2003

    • Author(s)
      Wakimoto K, Chiba H, Michibata H, Seishima M, Kawasaki S, Okubo K, Mitsui H, Torii H, Imai Y.
    • Journal Title

      Biochem Biophys Res Commun. 310

      Pages: 296-302

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Induction of glia maturation factor-beta in proximal tubular cells leads to vulnerability to oxidative injury through the p38 pathway and changes in antioxidant enzyme activities.2003

    • Author(s)
      Kaimori JY, Takenaka M, Nakajima H, Hamano T, Horio M, Sugaya T, Ito T, Hori M, Okubo K, Imai E.
    • Journal Title

      J. Biol Chem. 278

      Pages: 33519-33527

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Knowledge Discovery from the Human Transcriptome. Introduction to Bioinformatics 「A Theoretical And Practical Approach2003

    • Author(s)
      Okubo K., Hishiki T.
    • Journal Title

      Humana Press

      Pages: 693-717

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Zipfs law and human transcriptomes : an explanation with an evolutionary model.2003

    • Author(s)
      Ogasawara, O., Kawamoto, S., Okubo, K.
    • Journal Title

      C R Biol. 326

      Pages: 1097-1101

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube.2002

    • Author(s)
      Takebayashi H, Ohtsuki T, Uchida T, Kawamoto S, Okubo K, Ikenaka K, Takeichi M, Chisaka O, Nabeshima Y.
    • Journal Title

      Mech Dev. 113

      Pages: 169-74

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Expression map of human genes : between genome and proteome2002

    • Author(s)
      Tamura T, Okubo K.
    • Journal Title

      Tanpakushitsu Kakusan Koso. 47

      Pages: 906-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Construction of human corneal endothelial cDNA library and identification of novel active genes.2002

    • Author(s)
      Sakai R, Kinouchi T, Kawamoto S, Dana MR, Hamamoto T, Tsuru T, Okubo K, Yamagami S.
    • Journal Title

      Invest Ophthalmol Vis Sci. 43

      Pages: 1749-56

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Knowledge Discovery from the Human Transcriptome 「Introduction to Bioinformatics A Theoretical And Practical Approach」2002

    • Author(s)
      Okubo K., Hishiki T.
    • Journal Title

      (Krawetz, SA., Womble, DD. ed.) Human Press

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Gene expression profile of renal proximal tubules regulated by proteinuria.2002

    • Author(s)
      Nakajima H, Takenaka M, Kaimori JY, Nagasawa Y, Kosugi A, Kawamoto S, Imai E, Hori M, Okubo K.
    • Journal Title

      Kidney Int. 61

      Pages: 1577-87

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Expression profile of active genes in the human pituitary gland.2002

    • Author(s)
      Tanaka S, Tatsumi K, Okubo K, Itoh K, Kawamoto S, Matsubara K, Amino N.
    • Journal Title

      J Mol Endocrinol. 28

      Pages: 33-44

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Bodymap an anatomical gene expression database of human and mouse 「Analysing GeneExpression」2002

    • Author(s)
      Kawamoto S., Okubo K.
    • Journal Title

      Wiley (Lorkowski and Cullen ed.)

      Pages: 57-58

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Gene expression profiling of mucosal addressin cell adhesion molecule-1+ high endothelial venule cells(HEV) and identification of a leucine-rich HEV glycoprotein as a HEV marker.2002

    • Author(s)
      Saito K, Tanaka T, Kanda H, Ebisuno Y, Izawa D, Kawamoto S, Okubo K, Miyasaka M.
    • Journal Title

      J Immunol. 168

      Pages: 1050-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] iAFLP-introduced amplified length polymorphism [Analysing Gene Expression」2002

    • Author(s)
      Okubo K.
    • Journal Title

      Wiley (Lorkowski and Cullen ed.)

      Pages: 98-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] An expression profile of active genes in human conjunctival epithelium.2001

    • Author(s)
      Dota A, Nishida K, Adachi W, Nakamura T, Koizumi N, Kawamoto S, Okubo K, Kinoshita S.
    • Journal Title

      Exp Eye Res. 72

      Pages: 235-41

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Knowledge Dicovery from transcriptome In Introduction to Bioinformatics.2001

    • Author(s)
      Okubo K.Hishiki T.
    • Journal Title

      (S.A.Krawetzed.)Humana Press (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Characteristics of the human ocular surface epithelium.2001

    • Author(s)
      Kinoshita S, Adachi W, Sotozono C, Nishida K, Yokoi N, Quantock A, Okubo K.
    • Journal Title

      Prog Retin Eye Res. 20

      Pages: 639-673

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Cloning and characterization of a novel subunit of protein serine/threonine phosphatase 4 from mesangial cells.2001

    • Author(s)
      Wada T, Miyata T, Inagi R, Nangaku M, Wagatsuma M, Suzuki D, Wadzinski BE, Okubo K, Kurokawa K.
    • Journal Title

      J Am Soc Nephrol. 12

      Pages: 2601-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] BodyMap incorporated PCR-based expression profiling data and a gene ranking system.2001

    • Author(s)
      Sese J, Nikaidou H, Kawamoto S, Minesaki Y, Morishita S, Okubo K.
    • Journal Title

      Nucleic Acids Res. 29

      Pages: 156-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Gene expression analysis on several human tissues.2001

    • Author(s)
      Kawasaki S, Okubo K.
    • Journal Title

      Tanpakushitsu Kakusan Koso. 46

      Pages: 2351-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Characteristics of the human ocular surface epithelium.2001

    • Author(s)
      Kinoshita S, Adachi W, Sotozono C, Nishida K, Yokoi N, Quantock AJ, Okubo K.
    • Journal Title

      Prog Retin Eye Res. 20

      Pages: 639-73

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Identification and characterization of the potential promoter regions of 1031 kinds of human genes.2001

    • Author(s)
      Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, Ota T, Isogai T, Tanaka T, Nakamura Y, Suyama A, Sakaki Y, Morishita S, Okubo K, Sugano S.
    • Journal Title

      Genome Res. 11

      Pages: 677-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Isolation of novel heart-specific genes using the BodyMap database.2001

    • Author(s)
      Soejima H, Kawamoto S, Akai J, Miyoshi O, Arai Y, Morohka T, Matsuo S, Niikawa N, Kimura A, Okubo K, Mukai T.
    • Journal Title

      Genomics. 74

      Pages: 115-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] BodyMap a human and mouse gene expression database.2000

    • Author(s)
      Hishiki T, Kawamoto S, Morishita S, Okubo K.
    • Journal Title

      Nucleic Acids Res. 28

      Pages: 136-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Isolation and characterization of a Ca(2+)-activated chloride channel from human corneal epithelium.2000

    • Author(s)
      Itoh R, Kawamoto S, Miyamoto Y, Kinoshita S, Okubo K.
    • Journal Title

      Curr Eye Res. 21

      Pages: 918-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Human uroplakin Ib in ocular surface epithelium.2000

    • Author(s)
      Adachi W, Okubo K, Kinoshita S.
    • Journal Title

      Invest Ophthalmol Vis Sci. 41

      Pages: 2900-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Clinical significance of micrometastases in axillary lymph nodes assessed by reverse transcription-polymerase chain reaction in breast cancer patients.2000

    • Author(s)
      Masuda N, Tamaki Y, Sakita I, Ooka M, Ohnishi T, Kadota M, Aritake N, Okubo K, Monden M.
    • Journal Title

      Clin Cancer Res. 6

      Pages: 4176-85

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Journal Article] Gene expression profiles of the collecting duct in the mouse renal inner medulla.2000

    • Author(s)
      Takenaka M, Imai E, Nagasawa Y, Matsuoka Y, Moriyama T, Kaneko T, Hori M, Kawamoto S, Okubo K.
    • Journal Title

      Kidney Int. 57

      Pages: 19-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Patent] 注目する情報を知識集積物との関係で可視的に処理するた2002

    • Inventor(s)
      大久保公策
    • Industrial Property Rights Holder
      大久保公策
    • Industrial Property Number
      2004-073614
    • Filing Date
      2002
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204006
  • [Presentation] Annotating Cohesive Statements of Anatomical Knowledge Toward Semi-Automated Information Extraction2014

    • Author(s)
      Kazuo Hara, Ikumi Suzuki, Kousaku Okubo, Isamu Muto
    • Organizer
      6th International Conference on Knowledge Discovery and Information Retrieval (KDIR)
    • Place of Presentation
      Barcelo Aran Mantegna Hotel, Rome, Italy
    • Year and Date
      2014-10-23
    • Data Source
      KAKENHI-PROJECT-24500193
  • [Presentation] 科学を社会に役立てるには2008

    • Author(s)
      大久保公策
    • Organizer
      (独)日本学術振興会ゲノムテクノロジー第164委員会第27回研究会
    • Place of Presentation
      東京大学山上会館
    • Year and Date
      2008-07-22
    • Data Source
      KAKENHI-PROJECT-17017037
  • [Presentation] 生命科学分野でのDB統合の意味と意義2007

    • Author(s)
      大久保公策
    • Organizer
      日本バイオインフォマティクス学会第1回JSBi合同研究会
    • Place of Presentation
      東京大学医科学研究所
    • Year and Date
      2007-05-29
    • Data Source
      KAKENHI-PROJECT-17017037
  • 1.  KINOSHITA Shigeru (30116024)
    # of Collaborated Projects: 4 results
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  • 2.  NISHIDA Kohji (40244610)
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  • 3.  ITOH Takashi (90201326)
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  • 49.  ROIZES GERAR
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  DANCHIN ANTO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  DELABAR JEAN
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  GALIBERT FRA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  SLONIMSKI PI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  加藤 誠志
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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