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YANAGIHARA Katsunori  柳原 克紀

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YANAGIHARA K.  柳原 克紀

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Researcher Number 40315239
Other IDs
External Links
Affiliation (Current) 2022: 長崎大学, 医歯薬学総合研究科(医学系), 教授
Affiliation (based on the past Project Information) *help 2015 – 2022: 長崎大学, 医歯薬学総合研究科(医学系), 教授
2011: 長崎大学, 大学院・医歯薬学総合研究科, 准教授
2009 – 2010: Nagasaki University, 病院, 講師
2008: 長崎大学, 長崎大学附属病院, 講師
2006: 長崎大学, 医学部・歯学部付属病院, 講師 … More
2006: Nagasaki University, Laboratory Medicine University Hospital, lecturer, 医学部・歯学部附属病院, 講師
2005: 長崎大学, 大学院・医歯薬学総合研究科, 助手
2002: 長崎大学, 大学院・医歯薬学総合研究科, 助手
2001: 長崎大学, 大学院・薬学研究科, 助手
1999 – 2000: 長崎大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Infectious disease medicine / Respiratory organ internal medicine / Respiratory organ internal medicine / Basic Section 54030:Infectious disease medicine-related
Except Principal Investigator
Basic Section 52010:General internal medicine-related / Applied pharmacology / Respiratory organ internal medicine / Laboratory medicine / Hygiene and public health / Infectious disease medicine … More / Basic Section 54030:Infectious disease medicine-related / Basic Section 54020:Connective tissue disease and allergy-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 53030:Respiratory medicine-related Less
Keywords
Principal Investigator
MRSA / 病原因子 / SiRNA / マイクロバイオーム / コアグラーゼ / VISA / リネゾリド / バイオフィルム / マクロライド / 緑膿菌エラスターゼ … More / 慢性気道感染症 / オキサゾリジノン / エラスターゼ / 分子疫学解析 / 薬剤耐性菌 / 遺伝子診断 / 呼吸器感染症 / 遺伝子治療 / 肺炎球菌 / 緑膿菌 / respiratory infection / gene therapy / pathogenesis / pneumococcus / Pseudomonas aeruginosa / 高齢者肺炎 / 予防法 / 気道定着 / 肺炎 / dysbiosis / 高齢者 / 感染症 / 予防 / 腸内細菌叢 / ESBL産生細菌 / ST131 / 接合伝達実験 / ESBL産生菌 / ESBL産生腸内細菌 … More
Except Principal Investigator
HTLV-1 / 遺伝子検査 / 組み込み部位 / ATL / ファーマコゲノミクス / 抗結核剤 / 副作用 / 薬物代謝・解毒酵素遺伝子 / 抗酸化関連遺伝子 / 一塩基多型(SNPs) / 候補遺伝子アプローチ法 / 相関解析 / 遺伝子診断法 / 肝障害 / 症例-対照研究 / 慢性気道感染症モデル / 緑膿菌 / マクロライド / サイトカイン / 肺内リンパ球 / Chronic infection model / Pseudomonas aeruginosa / Macrolide / Cytokine / Lymphocyte of lung / 細胞株 / 分子標的 / 表面抗原 / 遺伝子発現解析 / バイオマーカー / Tuberculosis / Malnutrition / Diabetes / Immune function / Patient costs / Psychosocial health / TB / Nutrition / immune function / patient costs / psychosocial health / tuberculosis / malnutrition / diabetes / 栄養学 / インフルエンザウイルス / 肺炎球菌 / オートファジー / オートファジー阻害薬 / 敗血症 / 迅速細菌検査 / Tmマッピング法 / 敗血症起因菌定量検査 / 敗血症バイオマーカー / ATP測定 / NF-κB / 迅速起因菌同定定性検査 / 迅速起因菌菌数検査 / 起炎菌迅速検査 / 細菌数定量検査 / ATP活性検査 / 迅速起炎菌同定検査 / 細菌数定量 / 感染症迅速検査 / ATP検査 / 起因菌 / 起炎菌迅速同定法 / 感染症 / NF-kappa B / 成人T細胞白血病・リンパ腫(ATL) / 発症クローン / クロナリティ検査 / 成人T細胞白血病 / 成人T 細胞白血病 / 組込み部位 / 肺非結核性抗酸菌症 / 腸内細菌叢解析 / 簡易型自記式食事歴法質問票(BDHQ) / 腸内細菌叢 / 関節リウマチ / 発症予測 / 人工知能 / Viral hepatitis / genotype / drug resistant / therapeutic / Nigeria / 肺リンパ腫 / 診断 / 分子生物学的手法 / 遺伝子転座 / クローナリティー / フローサイトメトリー / 気管支肺胞洗浄 / リンパ腫 / 気管支肺胞洗浄液 Less
  • Research Projects

    (17 results)
  • Research Products

    (90 results)
  • Co-Researchers

    (75 People)
  •  Establishment of a novel test method for HTLV-1 clonality that captures the onset of ATL

    • Principal Investigator
      長谷川 寛雄
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Nagasaki University
  •  Molecular epidemiology, antiviral resistant variants and therapeutic options of hepatitis B and C in Nigeria

    • Principal Investigator
      吉田 レイミント
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Nagasaki University
  •  関節炎が起こる前段階で関節リウマチの発症を人工知能で予測する多角的研究

    • Principal Investigator
      玉井 慎美
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Nagasaki University
  •  肺リンパ腫における気管支肺胞洗浄液を用いた内科的診断手法の確立

    • Principal Investigator
      原 敦子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nagasaki University
  •  The analysis of microbiota for intestinal colonization of ESBL-producing bacteriaPrincipal Investigator

    • Principal Investigator
      柳原 克紀
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      Nagasaki University
  •  Analysis of the relationship between the gut microbiome and pulmonary non-tuberculous mycobacteriosis

    • Principal Investigator
      今村 圭文
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      Nagasaki University
  •  Construction of a comprehensive sepsis testing system based on the new sepsis definition and its operational deployment in Japan and Southeast Asia.

    • Principal Investigator
      Kitajima Isao
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      University of Toyama
  •  Establishment of individualized test method for HTLV-1 carriers based on identification and analysis of ATL-onset clones

    • Principal Investigator
      HASEGAWA Hiroo
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Nagasaki University
  •  Effects of malnutrition and diabetes on treatment outcome and total patient costs in Filipino drug resistant and drug sensitive patients starting anti-TB treatment: A cohort study.

    • Principal Investigator
      COX Sharon
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene and public health
    • Research Institution
      Nagasaki University
  •  Exploration new biomarkers based on HTLV-1 carrier clone analysis

    • Principal Investigator
      HASEGAWA Hiroo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagasaki University
  •  Elucidation of pathological condition of Elderly people pneumonia via analysis of microbiotaPrincipal Investigator

    • Principal Investigator
      YANAGIHARA Katsunori
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Nagasaki University
  •  The role of autophagy in severe influenza-related pneumonia

    • Principal Investigator
      KOSAI Kosuke
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Nagasaki University
  •  Molecular characteristic of Community-Acquired methicillin-resistant Staphylococcus aureus isolates by using New Genetic DiagnosisPrincipal Investigator

    • Principal Investigator
      YANAGIHARA Katsunori
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Nagasaki University
  •  Establishment of DNA-based diagnosis for detecting tuberculosis patients with anti-tuberculosis drug-induced side effects

    • Principal Investigator
      TSUKAMOTO Kazuhiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Nagasaki University
  •  The treatment against respiratory infection -gene therapy with SiRNA-Principal Investigator

    • Principal Investigator
      YANAGIHARA K.
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagasaki University
  •  耐性菌感染症に対するアンチセンスヌクレオチドを用いた遺伝子治療Principal Investigator

    • Principal Investigator
      柳原 克紀
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagasaki University
  •  Analysis of chronic respiratory infection by using a newly established murine model chronic respiratory infection with Pseudomonas aeruginosa-The kinetics of cytokines and analysis of the effect of macrolides-

    • Principal Investigator
      KOHNO Shigeru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagasaki University

All 2022 2021 2020 2019 2018 2017 2016 2015 2012 2011 2010 2009 2007 2006 2005

All Journal Article Presentation Book

  • [Book] マイクロバイオームと感染症研究の進歩2018

    • Author(s)
      栁原克紀
    • Total Pages
      606
    • Publisher
      最新医学社
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Book] 人工呼吸2018

    • Author(s)
      賀来 敬仁、栁原 克紀
    • Total Pages
      6
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Book] Drug Delivery Sysstem2018

    • Author(s)
      賀来 敬仁、栁原 克紀
    • Total Pages
      7
    • Publisher
      日本DDS学会
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Book] 「高齢者疾患とマイクロバイオーム」高齢者肺炎とマイクロバイオーム、2017

    • Author(s)
      賀来敬仁、栁原克紀、
    • Total Pages
      4
    • Publisher
      THE LUNG perspectives
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Book] 医療スタッフのための微生物検査のススメ2017

    • Author(s)
      柳原克紀編
    • Total Pages
      180
    • Publisher
      ヴァンメディカル
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Escherichia coli ST131 isolated from urological patients can acquire plasmid‐mediated extended spectrum β‐lactamase from other bacteria with high frequency2022

    • Author(s)
      Kondo T, Sakamoto K, Morinaga Y, Miyata Y, Yanagihara K, Sakai H.
    • Journal Title

      International Journal of Urology

      Volume: -

    • DOI

      10.1111/iju.14845

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08842, KAKENHI-PROJECT-20K08843
  • [Journal Article] Pulmonary nodular lymphoid hyperplasia evaluated with bronchoalveolar lavage fluid findings: A case report and review of literature on Japanese patients Internal medicine.2022

    • Author(s)
      Moriyama S, Kido, Sakamoto N, Fuchigami M, Tokito T, Okuno D, Miyamura T, Nakashima S, Hara A, Ishimoto H, Imaizumi Y, Tsuruda K, Yanagihara K, Fukuoka J, Mukae H.
    • Journal Title

      Internal Medicine

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08156
  • [Journal Article] TAS‐116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T‐cell leukemia2021

    • Author(s)
      Ikebe Emi、Shimosaki Shunsuke、Hasegawa Hiroo、Iha Hidekatsu、Tsukamoto Yoshiyuki、Wang Yu、Sasaki Daisuke、Imaizumi Yoshitaka、Miyazaki Yasushi、Yanagihara Katsunori、Hamaguchi Isao、Morishita Kazuhiro
    • Journal Title

      Cancer Science

      Volume: 113 Pages: 684-696

    • DOI

      10.1111/cas.15204

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02733, KAKENHI-PROJECT-20K17390
  • [Journal Article] Serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae associated with invasive pneumococcal disease among adults in Japan2021

    • Author(s)
      Yanagihara Katsunori、Kosai Kosuke、Mikamo Hiroshige、Mukae Hiroshi、Takesue Yoshio、Abe Machiko、Taniguchi Kazuko、Petigara Tanaz、Kaku Mitsuo
    • Journal Title

      International Journal of Infectious Diseases

      Volume: 102 Pages: 260-268

    • DOI

      10.1016/j.ijid.2020.10.017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02728
  • [Journal Article] The global dissemination of hospital clones of Enterococcus faecium2021

    • Author(s)
      van Hal Sebastiaan J.、Enterococcal Group、Willems Rob J. L.、Gouliouris Theodore、Ballard Susan A.、Coque Teresa M.、Hammerum Anette M.、Hegstad Kristin、Westh Hendrik T.、Howden Benjamin P.、Malhotra-Kumar Surbhi、Werner Guido、Yanagihara Katsunori、Earl Ashlee M.、Raven Katherine E.、Corander Jukka、Bowden Rory
    • Journal Title

      Genome Medicine

      Volume: 13

    • DOI

      10.1186/s13073-021-00868-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02728
  • [Journal Article] Tocilizumab has no direct effect on cell lines infected with human T-cell leukemia virus type 12021

    • Author(s)
      Endo Y, Fukui S, Koga T, Sasaki D, Hasegawa H, Yanagihara K, Okayama A, Nakamura T, Kawakami A, Nakamura H. Tocilizumab has no direct effect on cell lines infected with human T-cell leukemia virus type 1.
    • Journal Title

      Journal of International Medical Research

      Volume: 49 Pages: 1-10

    • DOI

      10.1177/03000605211002083

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08884, KAKENHI-PROJECT-19K08886, KAKENHI-PROJECT-18H02733, KAKENHI-PROJECT-19K17888
  • [Journal Article] Evaluation of a novel rapid TRC assay for the detection of influenza using nasopharyngeal swabs and gargle samples.2021

    • Author(s)
      Kaku N, Hashiguchi K, Akamatsu N, Wakigawa F, Matsuda J, Komaru K, Nakao T, Harada Y, Hara A, Uno N, Sakamoto K, Morinaga Y, Kitazaki T, Hasegawa H, Miyazaki T, Fukuda M, Izumikawa K, Mukae H, Yanagihara K.
    • Journal Title

      Eur J Clin Microbiol Infect Dis.

      Volume: - Pages: 1743-1748

    • DOI

      10.1007/s10096-021-04193-7

    • NAID

      120007000285

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08842, KAKENHI-PROJECT-18H02728
  • [Journal Article] Flow cytometry assay for the detection of single-copy DNA in human lymphocytes.2020

    • Author(s)
      Uno Naoki、Kaku Norihito、Morinaga Yoshitomo、Hasegawa Hiroo、Yanagihara Katsunori
    • Journal Title

      Nucleic Acids Res

      Volume: 48

    • DOI

      10.1093/nar/gkaa515

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-18H02733
  • [Journal Article] HTLV-1 targets human placental trophoblasts in seropositive pregnant women.2020

    • Author(s)
      Tezuka Kenta、Fuchi Naoki、Okuma Kazu、Tsukiyama Takashi、Miura Shoko、Hasegawa Yuri、Nagata Ai、Komatsu Nahoko、Hasegawa Hiroo、Sasaki Daisuke、Sasaki Eita、Mizukami Takuo、Kuramitsu Madoka、Matsuoka Sahoko、Yanagihara Katsunori、Miura Kiyonori、Hamaguchi Isao
    • Journal Title

      J Clin Invest

      Volume: 130 Pages: 6171-6186

    • DOI

      10.1172/jci135525

    • NAID

      40022604515

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09265, KAKENHI-PROJECT-20K07670, KAKENHI-PROJECT-18K16805, KAKENHI-PROJECT-19K16032, KAKENHI-PROJECT-18H02733, KAKENHI-PROJECT-17K11241, KAKENHI-PROJECT-18K08378
  • [Journal Article] Treatment of severe pneumonia by hinokitiol in a murine antimicrobial-resistant pneumococcal pneumonia model2020

    • Author(s)
      Isono Toshihito、Domon Hisanori、Nagai Kosuke、Maekawa Tomoki、Tamura Hikaru、Hiyoshi Takumi、Yanagihara Katsunori、Kunitomo Eiji、Takenaka Shoji、Noiri Yuichiro、Terao Yutaka
    • Journal Title

      PLOS ONE

      Volume: 15

    • DOI

      10.1371/journal.pone.0240329

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09903, KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-19H03828, KAKENHI-PROJECT-20J15490, KAKENHI-PROJECT-19K22706
  • [Journal Article] A Methodology for Assessing Tumor Clonality of Adult T Cell Leukemia/Lymphoma.2020

    • Author(s)
      Yamakawa T, Uno N, Sasaki D, Kaku N, Sakamoto K, Kosai K, Hasegawa H, Miyazaki Y, Yanagihara K.
    • Journal Title

      Mol Ther Methods Clin Dev

      Volume: 19 Pages: 463-473

    • DOI

      10.1016/j.omtm.2020.10.015

    • NAID

      120006980751

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08842, KAKENHI-PROJECT-18H02733
  • [Journal Article] Novel and potent antimicrobial effects of caspofungin on drug-resistant Candida and bacteria2020

    • Author(s)
      Sumiyoshi Makoto、Miyazaki Taiga、Makau Juliann Nzembi、Mizuta Satoshi、Tanaka Yoshimasa、Ishikawa Takeshi、Makimura Koichi、et al.
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 17745-17745

    • DOI

      10.1038/s41598-020-74749-8

    • NAID

      120006988489

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07540, KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-17K09618, KAKENHI-PROJECT-18K11536, KAKENHI-PROJECT-20H04285
  • [Journal Article] Discrepancies in preferences regarding the care of terminal-phase pneumonia in elderly patients among patients, families, and doctors: A multicenter questionnaire survey in nagasaki, Japan2020

    • Author(s)
      Takazono Takahiro、Imamura Yoshifumi、Kawakami Kaoru、Yamasaki Naoya、Shimizu Hiroyoshi、Usuki Katsuhiro、Kiyohara Maiko、Hirayama Tatsuro、Tashiro Masato、Hosogaya Naoki、Saijo Tomomi、Yamamoto Kazuko、Miyazaki Taiga、Yanagihara Katsunori、Izumikawa Koichi、Mukae Hiroshi
    • Journal Title

      Respiratory Investigation

      Volume: 58 Pages: 488-494

    • DOI

      10.1016/j.resinv.2020.05.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02728
  • [Journal Article] Multicenter surveillance of the epidemiology of gram-negative bacteremia in Japan2020

    • Author(s)
      Kosai Kosuke、Yamagishi Yuka、Hashinaga Kazuhiko、Nakajima Kazuhiko、Mikamo Hiroshige、Hiramatsu Kazufumi、Takesue Yoshio、Yanagihara Katsunori
    • Journal Title

      Journal of Infection and Chemotherapy

      Volume: 26 Pages: 193-198

    • DOI

      10.1016/j.jiac.2019.11.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02728
  • [Journal Article] A high-throughput detection method for the clonality of Human T-cell leukemia virus type-1-infected cells in vivo2020

    • Author(s)
      Masumichi Saito, Hiroo Hasegawa, Shunsuke Yamauchi, et al.
    • Journal Title

      Int J Hematol

      Volume: 112 Issue: 3 Pages: 300-306

    • DOI

      10.1007/s12185-020-02935-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08868, KAKENHI-PROJECT-20K07670, KAKENHI-PROJECT-17H03594, KAKENHI-PROJECT-18H02733, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-18K08317, KAKENHI-PROJECT-19K16580, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277
  • [Journal Article] The Effect of In Vitro Hemolysis on Measurement of Cell-Free DNA2019

    • Author(s)
      Nishimura F, Uno N, Chiang PC, Kaku N, Morinaga Y, Hasegawa H, Yanagihara K
    • Journal Title

      J Appl Lab Med

      Volume: 4(2) Pages: 235-240

    • DOI

      10.1373/jalm.2018.027953

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08986, KAKENHI-PROJECT-18H02733
  • [Journal Article] Nationwide surveillance of bacterial respiratory pathogens conducted by the surceillance committee of Japanese Society of Chemoterapy, the Japanese association for Infectious Diseases, and the Japanese Society for clinical microbiology in 2014: General view of pathogens' antibacterial susceptibity.2019

    • Author(s)
      Yanagihara K, Matumoto T, Aoki N, Sato J, Wakamura T, Kiyota H, et al.
    • Journal Title

      J.Infect Chemother

      Volume: 25(9) Pages: 657-668

    • DOI

      10.1016/j.jiac.2019.05.006

    • Data Source
      KAKENHI-PROJECT-18H02728
  • [Journal Article] The role of molecular diagnosis in acute respiratory tract infection.2019

    • Author(s)
      Yanagihara K
    • Journal Title

      Repir. Investig.

      Volume: 57(6) Pages: 511-511

    • DOI

      10.1016/j.resinv.2019.06.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02728
  • [Journal Article] Molecular epidemiology of Clostridioides difficile and risk factors for the detection of toxin gene-positive strains.2019

    • Author(s)
      Okada Y, Kaku N, Kosai K, Uno N, Morinaga Y, Hasegawa H, Yanagihara K.
    • Journal Title

      J Infect Chemother

      Volume: 4 Pages: 262-266

    • DOI

      10.1016/j.jiac.2018.12.004

    • NAID

      120007000280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Exploring the microbiota of upper respiratory tract during the development of pneumonia in a mouse model2019

    • Author(s)
      Morinaga Y, Take Y, Sasaki D, Ota K, Kaku N, Uno N, Sakamoto K, Kosai K, Miyazaki T, Hasegawa H, Izumikawa K, Mukae H, Yanagihara K
    • Journal Title

      PLoS One

      Volume: 14(9)

    • DOI

      10.1371/journal.pone.0222589

    • NAID

      120006988400

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Journal Article] Diversity of cell phenotypes among MT-2 cell lines affects the growth of U937 cells and cytokine production.2019

    • Author(s)
      Nomura Hajime、Umekita Kunihiko、Hashikura Yuuki、Umeki Kazumi、Yamamoto Ikuo、Aratake Yatsuki、Saito Mineki、Hasegawa Hiroo、Yanagihara Katsunori、Okayama Akihiko
    • Journal Title

      Human Cell

      Volume: 32 Pages: 185-192

    • DOI

      10.1007/s13577-018-00231-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02733, KAKENHI-PROJECT-18K07541
  • [Journal Article] Oligosecretory Primary Plasma Cell Leukemia with Atypical Morphological Abnormality2019

    • Author(s)
      Toriyama E, Imaizumi Y, Tsuruda K, Itonaga H, Sato S, Ando K, Sawayama Y, Hasegawa H, Hata T, Niino D, Yanagihara K, Miyazaki Y
    • Journal Title

      Internal Medicine

      Volume: 17 Issue: 15 Pages: 2472-18

    • DOI

      10.2169/internalmedicine.2472-18

    • NAID

      130007686846

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10050, KAKENHI-PROJECT-17K16189, KAKENHI-PROJECT-18K16121, KAKENHI-PROJECT-18H02733
  • [Journal Article] Risk Factors for Acquisition of Fluoroquinolone or Aminoglycoside Resistance in Addition to Carbapenem Resistance in Pseudomonas aeruginosa.2018

    • Author(s)
      Kosai K, Kaku N, Uno N, Saijo T, Morinaga Y, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.
    • Journal Title

      Open Microbiol J

      Volume: 12 Pages: 321-322

    • NAID

      120006987429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Performance evaluation of the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay for the detection of IMP metallo-β-lactamase activity in Enterobacteriaceae.2018

    • Author(s)
      Kawamoto Y, Kosai K, Yamakawa H, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.
    • Journal Title

      Diagn Microbiol Infect Dis

      Volume: 92 Pages: 275-278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Evaluation of FilmArray respiratory panel multiplex polymerase chain reaction assay for detection of pathogens in adult outpatients with acute respiratory tract infection.2018

    • Author(s)
      Kaku N, Hashiguchi K, Iwanaga Y, Akamatsu N, Matsuda J, Kosai K, Uno N, Morinaga Y, Kitazaki T, Hasegawa H, Miyazaki T, Fukuda M, Izumikawa K, Mukae H, Yanagihara K.
    • Journal Title

      J Infect Chemother.

      Volume: 9 Pages: 734-738

    • DOI

      10.1016/j.jiac.2018.05.006

    • NAID

      120007000279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Natural Course of Human T-Cell Leukemia Virus Type 1 Proviral DNA Levels in Carriers During Pregnancy2018

    • Author(s)
      Fuchi N, Miura K, Tsukiyama T, Sasaki D, Ishihara K, Tsuruda K, Hasegawa H, Miura S, Yanagihara K, Masuzaki H
    • Journal Title

      J Infect Dis.

      Volume: 217 Pages: 1383-1389

    • DOI

      10.1093/infdis/jiy017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11241, KAKENHI-PROJECT-16K20198, KAKENHI-PROJECT-17K11283, KAKENHI-PROJECT-18K09265, KAKENHI-PROJECT-18K16805, KAKENHI-PROJECT-18H02733
  • [Journal Article] In Vitro Activity of Lascufloxacin against Streptococcus pneumoniae with Mutations in the Quinolone Resistance-Determining Regions2018

    • Author(s)
      Murata M, Kosai K, Yamauchi S, Sasaki D, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K
    • Journal Title

      Antimicrob Agents Chemother

      Volume: 62

    • NAID

      120006988021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Fluoroquinolone resistance in extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a Japanese tertiary hospital: silent shifting to CTX-M-15-producing K. pneumoniae.2017

    • Author(s)
      Higashino M, Murata M, Morinaga Y, Akamatsu N, Matsuda J, Takeda K, Kaku N, Kosai K, Uno N, Hasegawa H, Yanagihara K.
    • Journal Title

      Journal of Medical Microbiology.

      Volume: 66 Pages: 1476-82

    • DOI

      10.1099/jmm.0.000577

    • NAID

      120006987383

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Detection of Fusobacterium nucleatum in two cases of empyema and lung abscess using paromomycin-vancomycin supplemented Brucella HK agar.2017

    • Author(s)
      Nagaoka K, Yanagihara K, Morinaga Y, Kohno S.
    • Journal Title

      Anaerobe.

      Volume: 43 Pages: 99-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Infection of defective human T-lymphotropic virus type 12017

    • Author(s)
      Hashikura Yuuki、Umeki Kazumi、Umekita Kunihiko、Nomura Hajime、Yamada Akiteru、Yamamoto Ikuo、Hasegawa Hiroo、Yanagihara Katsunori、Okayama Akihiko
    • Journal Title

      Human Cell

      Volume: 30 Pages: 117-123

    • DOI

      10.1007/s13577-016-0156-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08647
  • [Journal Article] Performance evaluation of the Verigene ? Clostridium difficile nucleic acid test, an automated multiplex molecular testing system for detection of C.?difficile toxin2017

    • Author(s)
      Kosai K, Iwanaga Y, Akamatsu N, Okada Y, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.
    • Journal Title

      J Infect Chemoth

      Volume: 23 Pages: 674-677

    • DOI

      10.1016/j.jiac.2017.07.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09572, KAKENHI-PROJECT-16K09936
  • [Journal Article] Tumor necrosis factor alpha inhibitors have no effect on a human T-lymphotropic virus type-I (HTLV-I)-infected cell line from patients with HTLV-I-associated myelopathy2017

    • Author(s)
      Fukui S, Nakamura H, Takahashi Y, Iwamoto N, Hasegawa H, Yanagihara K, Nakamura T, Okayama A, Kawakami A.
    • Journal Title

      BMC Immunology

      Volume: 18 Pages: 1-10

    • DOI

      10.1186/s12865-017-0191-2

    • NAID

      120006987561

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-15K08647
  • [Journal Article] Clinical application of a ligation-independent pathway of multiplex ligation-dependent probe amplification for the determination of quinolone susceptibility of Streptococcus pneumoniae.2016

    • Author(s)
      Uno N, Araki N, Kaku N, Kosai K, Hasegawa H, Yanagihara K.
    • Journal Title

      J Microbiol Methods

      Volume: 128 Pages: 13-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Induction of apoptosis by HBI-8000 in adult T-cell leukemia/lymphoma is associated with activation of Bim and NLRP3.2016

    • Author(s)
      Hasegawa H, Bissonnette RP, Gillings M, Sasaki D, Taniguchi H, Kitanosono H, Tsuruda K, Kosai K, Uno N, Morinaga Y, Imaizumi Y, Miyazaki Y, Yanagihara K.
    • Journal Title

      Cancer Sci

      Volume: 107 Pages: 1124-33

    • DOI

      10.1111/cas.12971

    • NAID

      120006987664

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08647
  • [Journal Article] Premedication with clarithromycin is effective against secondary bacterial pneumonia during influenza virus infection in a pulmonary emphysema mouse model.2016

    • Author(s)
      Harada T, Ishimatsu Y, Hara A, Morita T, Nakashima S, Kakugawa T, Sakamoto N, Kosai Y, Izumikawa K, Yanagihara K, Mukae H, Kohno S
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics

      Volume: 358 Pages: 457-463

    • DOI

      10.1124/jpet.116.233932

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09936, KAKENHI-PROJECT-15K19587
  • [Journal Article] Quantitative RT-PCR evaluation of a rapid influenza antigen test for efficient diagnosis of influenza virus infection.2015

    • Author(s)
      Tsushima Y, Uno N, Sasaki D, Morinaga Y, Hasegawa H, Yanagihara K:
    • Journal Title

      J Virol Methods

      Volume: 212 Pages: 76-9

    • NAID

      120006987121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] 感染症迅速診断―これからの可能性―2015

    • Author(s)
      栁原克紀
    • Journal Title

      感染症

      Volume: 45 Pages: 123-130

    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Multicenter evaluation of the Verigene Gram-negative blood culture nucleic acid test for rapid detection of bacteria and resistance determinants in positive blood cultures2015

    • Author(s)
      Uno N, Suzuki H, Yamakawa H, Yamada M, Yaguchi Y, Notake S, Tamai K, Yanagisawa H, Misawa S, Yanagihara K.
    • Journal Title

      Diagn Microbiol Infect Dis

      Volume: 83 Pages: 344-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Journal Article] Antimicrobial susceptibility and molecular characteristic of 857 methicillin-resistant Staphylococcus aureus isolates from 16 medical centers in Japan(2008-2009): Nationwide survey of community-acquired and nosocomial MRSA2012

    • Author(s)
      Yanagihara K, Araki N, Watanabe S, Kinebuchi T, Kaku M, Maesakii S, Yamaguchi K, Matsumoto, Mikamo H, Takesue Y, Fujita J, Kadota J, Iwatsuki K, Hino H, Kaneko T, Asagoe K, Ikeda M, T Yasuoka A, Kohno S
    • Journal Title

      Diagn Microbiol Infect Dis

      Volume: 72 Pages: 253-257

    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Antimicrobial susceptibility and molecular characteristic of 857 methicillin-resistant Staphylococcus aureus isolates from 16 medical centers in Japan (2008-2009) : Nationwide survey of community-acquired and nosocomial MRSA2012

    • Author(s)
      Yanagihara K, et.al
    • Journal Title

      Diagn Microbiol Infect Dis

      Volume: 72 Pages: 253-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] High dose tobramycin inhibits lipopolysaccharide-induced MUC5AC production in human lung epithelial cells2011

    • Author(s)
      Nakamura S, Yanagihara K, Araki N, Morinaga Y, Yamada, K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Kamihira S, Kohno
    • Journal Title

      European Journal of Pharmacology

      Volume: 659 Pages: 67-71

    • NAID

      120006985129

    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] High dose tobramycin inhibits lipopolysaccharide-induced MUC5AC production in human lung epithelial cells. European Journal of Pharmacology2011

    • Author(s)
      Nakamura S, Yanagihara K, et.al
    • Journal Title

      European Journal of Pharmacology

      Volume: 659 Pages: 67-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Clinical characteristics of bacteremia caused by methicillin-resistant Staphylococcus aureus in a tertiary hospital2011

    • Author(s)
      Yamada K, Yanagihara K, Hara Y, Araki N, Harada Y, Morinaga Y, Matsuda J, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Kohno S, Kamihira S
    • Journal Title

      Tohoku J Exp Med

      Volume: 224 Pages: 61-67

    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Clinical characteristics of bacteremia caused by methicillin-resistant Staphylococcus aureus in a tertiary hospital2011

    • Author(s)
      Yamada K, Yanagihara K, et.al
    • Journal Title

      Tohoku J Exp Med

      Volume: 242 Pages: 61-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Azithromycin inhibits nontypeable Haemophilus infuenzae-induced MUC5AC expression and secretion via inhibition of activator protein -1 in human airway epithelial cells2010

    • Author(s)
      Araki N, Yanagihara, et al
    • Journal Title

      European Journal of Pharmacology

      Volume: 644 Pages: 209-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Evaluation of Pathogen Detection from Clinical Samples by Real-Time PCR using a Sepsis Pathogen, DNA Detection Kit.2010

    • Author(s)
      Yanagihara K, et al
    • Journal Title

      Critical Care.

      Volume: 14(4)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Evaluation of pathogen detection from clinical samples by real-time polymerase chain reaction using a sepsis pathogen DNA detection Kit2010

    • Author(s)
      Yanagihara K, Kitagawa Y, Tomonaga M, Tsukasaki K, Kohno S, Seki M, Sugimoto H, Shimazu T, Tasaki O, Matsushima A, Ikeda Y, Okamoto S, Aikawa N, Hori S, Obara H, Ishizaka A, Hasegawa N, Takeda J, Kamihira S, Sugahara K, Asari S, Murata M, Kobayashi Y, Gin
    • Journal Title

      Critical Care

      Volume: 14

    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Genetic diagnosis of community-acquired MRSA : A multiplex real-time PCR method for staphylococcal cassette chromosome mec typing and detecting toxin genes2010

    • Author(s)
      Motoshima M, Yanagihara K, Morinaga Y, Matsuda J, Sugahara K, Yamada Y, Kohno S, Kamihira S
    • Journal Title

      Tohoku J Exp Med

      Volume: 220 Pages: 165-170

    • NAID

      10027083430

    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Efficacy of linezolid against PVL-positive MRSA in a mouse model of hematogenous pulmonary infection2009

    • Author(s)
      Yanagihara K, et.al
    • Journal Title

      Int J Antimicrob Agents 34

      Pages: 477-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Efficacy of linezolid against PVL-positive MRSA in a mouse model of hematogenous pulmonary infection2009

    • Author(s)
      Yanagihara K, Kihara R, Araki N, Morinaga Y, Seki M, Izumikawa K, Kakeya H, Yamamoto Y, Yamada Y, Kamihira S, Tsukamoto K, Kohno S
    • Journal Title

      Int J Antimicrob Agents

      Volume: 34 Pages: 477-481

    • Data Source
      KAKENHI-PROJECT-21591294
  • [Journal Article] Effects of specific neutrophil elastase inhibitor, sivelestat sodium hydrate, in murine model of severe pneumococcal pneumonia.2007

    • Author(s)
      Yanagihara K., et al.
    • Journal Title

      Experimental Lung Research 33巻2号

      Pages: 71-80

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590796
  • [Journal Article] A haplotype,NAT2^+6A,of the N-acetyltransferase 2 gene is an important for a risk of anti-tuberculosis drug-induced hepatotoxicity in japanese patients with tuberculosis2007

    • Author(s)
      Higuchi N, Tahara N, Yanagihara K, Kohno S, Tsukamoto K, et al.
    • Journal Title

      World Journal of Gastroenterology, (in press)

    • Data Source
      KAKENHI-PROJECT-18390168
  • [Journal Article] Effects of specific neutrophil elastase inhibitor, sivelestat sodium hydrate, in murine model of severe pneumococcal pneumonia.2007

    • Author(s)
      Katsunori Yanagihara et al.
    • Journal Title

      Experimental Lung Research 33(2)

      Pages: 71-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590796
  • [Journal Article] Telithromycin inhibits the number of viable bacteria but not lymphocytes accumulation in murine model of chronic respiratory infection2007

    • Author(s)
      Yanagihara K., et al.
    • Journal Title

      Chemotherapy 53巻

      Pages: 10-13

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590796
  • [Journal Article] A haplotype, NAT2*6A, of the il, acetyltransferase 2 gene is an important biomarker for a risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis2007

    • Author(s)
      Higuchi N, Tahara N, Yanagihara K, Fukushima K, Suyama N, Inoue Y, Miyazaki Y, Kobayashi T, Yoshiura K, Niikawa N, Wen C-Y, Isomoto H, ShikuwaS, MizutaY, Kohno S, Tsukamoto K
    • Journal Title

      World Gastroenterol 13(45)

      Pages: 6003-6008

    • Data Source
      KAKENHI-PROJECT-18390168
  • [Journal Article] A haplotype, NAT2*6A, of the N-acetyltransferase 2 gene is an important biomarker for a risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis2007

    • Author(s)
      Higuchi N, Tahara N, Yanagihara K, Kohno S, Tsukamoto K, et. al.
    • Journal Title

      World Journal of Gastroenterology 13(45)

      Pages: 6003-6008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390168
  • [Journal Article] Effect of anti-PcrV Antibody in Murine Chronic Airway Pseudomonas aeruginosa Infection Model2007

    • Author(s)
      Imamura Y, Yanagihara K., et al.
    • Journal Title

      European Respiratory Journal 54(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590796
  • [Journal Article] Effects of anti-PcrV Antibody in Murine Chronic Airway Pseudomonas aeruginosa Infection Model2007

    • Author(s)
      Imamura Y, Yanagihara K, et al.
    • Journal Title

      European Repiratory Journal 29巻(In press)

    • Data Source
      KAKENHI-PROJECT-17590796
  • [Journal Article] In vivo efficacies and pharmacokinetics of DX-619, a novel des-fluoro(6) quinolone, against Streptococcus pneumoniae in a mouse lung infection model.2006

    • Author(s)
      Fukuda Y, Yanagihara K., et al.
    • Journal Title

      Antimicrobial Agents and Chemotherapy. 50

      Pages: 121-125

    • Data Source
      KAKENHI-PROJECT-17590796
  • [Journal Article] Effects of short interfering RNA against methicillin-resistant Staphylococcus aureus coagulase in vitro and in vivo.2006

    • Author(s)
      Yanagihara K., et al.
    • Journal Title

      Journal of Antimicrobial Chemotherapy 57

      Pages: 122-126

    • Data Source
      KAKENHI-PROJECT-17590796
  • [Journal Article] Effects of macrolides against pneumolysin of macrolide-resistant Streptococcus pneumoniae2006

    • Author(s)
      Fukuda Y, Yanagihara K, et al.
    • Journal Title

      European Repiratory Journal 27巻5号

      Pages: 1020-5

    • Data Source
      KAKENHI-PROJECT-17590796
  • [Journal Article] Role of Pseudomonas aeruginosa quorum-sensing systems in a mouse model of chronic respiratory infection.2005

    • Author(s)
      Imamura Y, Yanagihara K., et al.
    • Journal Title

      Journal of Medical Microbiology 54

      Pages: 515-518

    • Data Source
      KAKENHI-PROJECT-17590796
  • [Presentation] 気管支肺胞洗浄が診断に寄与した成人T細胞白血病・リンパ腫の1例2021

    • Author(s)
      池谷 千章, 城戸 貴志, 原 敦子, 小笹 睦, 加藤 丈晴, 渕上 麻衣, 奥野 大輔, 宮村 拓人, 森山 咲子, 石本 裕士, 坂本 憲穂, 今泉 芳孝, 尾長谷 靖, 鶴田 一人, 石松 祐二, 柳原 克紀, 福岡 順也, 迎 寛
    • Organizer
      第41回日本呼吸器内視鏡学会総会
    • Data Source
      KAKENHI-PROJECT-21K08156
  • [Presentation] 新規 HTLV-1 クロナリティ解析法(RAISING 法)による ATL の病態解析2021

    • Author(s)
      松本 成良、斎藤 益満、佐々木 大介、山内 俊輔、今泉 芳孝、長谷川 寛雄、宮﨑 泰司、栁原 克紀
    • Organizer
      第7回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] 気管支肺胞洗浄の詳細な解析が診断に寄与した濾胞性リンパ腫再発例2021

    • Author(s)
      末原 照大 、城戸 貴志 、坂本 憲穂 、小笹 睦 、時任 高諄 、奥野 大輔 、原 敦子 、 佐藤 信也 、石本裕士、今泉 芳孝、福岡 順也、栁原 克紀、迎 寛
    • Organizer
      第333回日本内科学会九州地方会
    • Data Source
      KAKENHI-PROJECT-21K08156
  • [Presentation] 成人T細胞白血病/リンパ腫のクローン構成を評価する新規方法の開発2021

    • Author(s)
      山川 智弘, 佐々木 大介, 太田 賢治, 加勢田 富士子, 長谷川 寛雄, 柳原 克紀
    • Organizer
      第68回日本臨床検査医学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] 寛解 17 年後に再発した成人 T 細胞白血病・リンパ腫2021

    • Author(s)
      西村 紗央里、加藤 丈晴、村山 直也、佐藤 信也、安東 恒史、松本 成良、佐々木 大介、澤山 靖、三好 寛明、今泉 芳孝、長谷川 寛雄、柳原 克紀、大島 孝一、宮﨑 泰司
    • Organizer
      第7回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] AML with t(8;21)(q22;q22.1)における細胞抗原発現の解析2020

    • Author(s)
      林田 章也、長谷川 寛雄、鶴田 一人、森 沙耶香、渕上 麻衣、山内 俊輔、岡本 南、高田 侑実、松本 慧介、柳原 克紀
    • Organizer
      日本検査血液学会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] 次世代HTLV-1クロナリティ解析法(RAIS1)の開発2020

    • Author(s)
      山内 俊輔、斎藤 益満,、長谷川 寛雄、佐々木 大介、渕上 麻衣、森 沙耶香、鶴田 一人、今泉 芳孝、宮崎 泰司、柳原 克紀
    • Organizer
      日本検査血液学会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] HTLV-1キャリアに対する血漿miRNAを用いたATL発症スクリーニング検査の確立2020

    • Author(s)
      新野 大介、佐々木 大介、山内 俊介、長谷川 寛雄、柳原 克紀、岩永 正子
    • Organizer
      日本病理学会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] 上気道感染症の検査と治療方針: 基本はアモキシシリン、応用は?2019

    • Author(s)
      栁原克紀
    • Organizer
      日本臨床微生物学会
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] 次世代HTLV-1 クロナリティ解析法(RAIS1)の開発とその進捗2019

    • Author(s)
      山内 俊輔、長谷川 寛雄、斎藤 益満、佐々木 大介、今泉 芳孝、柳原 克紀
    • Organizer
      第6回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] HTLV-1 ウイルス組み込み配列の決定およびクローン特異的定量PCR 法の開発2019

    • Author(s)
      山川 智弘、宇野 直輝、賀来 敬仁、坂本 啓、森永 芳智、長谷川 寛雄、栁原 克紀
    • Organizer
      第6回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] 敗血症における遺伝子関連検査の実運用~Verigeneシステムによる薬剤耐性菌の迅速検出~2018

    • Author(s)
      栁原克紀
    • Organizer
      日本感染症学会
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] 次世代HTLV-1クロナリティ解析法の開発2018

    • Author(s)
      山内俊輔、斎藤益満 、長谷川寛雄、佐々木大介、賀来敬仁、宇野直輝、森永芳智、今泉芳孝、宮﨑泰司、栁原克紀
    • Organizer
      第65回日本臨床検査医学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02733
  • [Presentation] 全国におけるグラム陰性桿菌を原因とする血流感染症のアンケート調査2018

    • Author(s)
      栁原克紀
    • Organizer
      日本化学療法学会
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] DDSがつくる、医療の未来2018

    • Author(s)
      栁原克紀
    • Organizer
      日本DDS学会
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] 2.妊婦スクリーニング検体のHTLV-1定量検査におけるデジタルPCR法とリアルタイムPCR法の比較2017

    • Author(s)
      淵 直樹,三浦 清徳,佐々木 大介,鶴田 一人,長谷川 寛雄,栁原 克紀,増崎 英明
    • Organizer
      第4回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08647
  • [Presentation] 微生物検査の進歩―感染症診断・制御における役割を考える―2017

    • Author(s)
      柳原克紀
    • Organizer
      第28回日本臨床微生物学会
    • Place of Presentation
      ブリックホール(長崎県・長崎市)
    • Year and Date
      2017-01-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] 1.臨床検体のHTLV-1定量検査におけるデジタルPCR法とリアルタイムPCR法の比較2017

    • Author(s)
      佐々木 大介,長谷川 寛雄,淵 直樹,三浦 清徳,上野 友郁,吉田 彩香,松本 成良,山川 嘉美,賀来 敬仁,小佐井 康介,宇野 直輝,増崎 英明,栁原 克紀
    • Organizer
      第4回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08647
  • [Presentation] Rapid Diagnostic Testing Systems for Sepsis in Japan2017

    • Author(s)
      Katsunori Yanagihara
    • Organizer
      Singapore International Infectious Disease Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] Newer diagnosis for drug resistant pathogens: now and beyond2017

    • Author(s)
      Katsunori Yanagihara
    • Organizer
      30th International Congress of Chemotherapy and Infection
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] 感染症治療と腸内細菌叢2017

    • Author(s)
      賀来敬仁、柳原克紀
    • Organizer
      第28回日本臨床微生物学会
    • Place of Presentation
      ブリックホール(長崎県・長崎市)
    • Year and Date
      2017-01-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] 感染症診断における新展開2015

    • Author(s)
      柳原克紀
    • Organizer
      日本感染症学会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2015-04-17
    • Data Source
      KAKENHI-PROJECT-15K09572
  • [Presentation] 結核患者における肝障害発現とROS関連遺伝子多型との相関解析2007

    • Author(s)
      柳原克紀, 田原尚子, 稲嶺達夫, 樋口則英, 小林奨, 関雅文, 泉川公一, 大野秀明, 宮崎義継, 平潟洋一, 塚元和弘, 河野茂
    • Organizer
      第47回日本呼吸器病学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390168
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