Yamamoto Yoshihiro 山本善裕

… Alternative Names

YAMAMOTO Yoshihiro 山本善裕

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Researcher Number	70452844
Other IDs
Affiliation (Current)	2025: 富山大学, 学術研究部医学系, 教授
Affiliation (based on the past Project Information) *help	2025: 富山大学, 学術研究部医学系, 教授 2019 – 2023: 富山大学, 学術研究部医学系, 教授 2017 – 2018: 富山大学, 大学院医学薬学研究部(医学), 教授
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 47060:Clinical pharmacy-related / Basic Section 52010:General internal medicine-related / Medical pharmacy
Keywords	Principal Investigator 抗MRSA薬 / 抗菌薬適正使用 / タンパク質結合理論 / 治療薬物モニタリング / TDM / 唾液中薬物濃度 / 抗ＭＲＳＡ薬 / 生理学的薬物動態/薬力学モデル / 特殊病態患者 / 抗菌薬投与設計 / 薬物濃度 … More Except Principal Investigator … More Tmマッピング法 / 小児 / 感染症 / 成熟度 / 膵切除 / PCR / 膵頭十二指腸切除 / 薬物療法 / 乳幼児 / 薬物治療 / 薬物動態 / 深層学習 / 数理モデル / 人工知能 / NF-kappa B / 起炎菌迅速同定法 / 起因菌 / ATP検査 / 感染症迅速検査 / 遺伝子検査 / 細菌数定量 / 迅速起炎菌同定検査 / ATP活性検査 / 細菌数定量検査 / 起炎菌迅速検査 / 迅速起因菌菌数検査 / 迅速起因菌同定定性検査 / NF-κB / ATP測定 / 敗血症バイオマーカー / 敗血症起因菌定量検査 / 迅速細菌検査 / 敗血症 / 薬学 / 小児・妊婦 / 薬物動態解析 / 抗菌薬 / 肝・腎機能障害患者 / 高齢者 / 尿細管再吸収機構 / 血小板 / C-反応性たんぱく / ファーマコロジー / ファーマコキネティクス / クリニカルファーマコメトリクス Less

タンパク質結合理論を基盤とした薬効直結型の抗MRSA薬TDM手法の開発Principal Investigator
- Principal Investigator
  
  山本善裕
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  University of Toyama
膵頭十二指腸切除周術期に複合的迅速微生物検査を応用した新たな抗菌治療戦略の構築
- Principal Investigator
  
  藤井努
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Toyama
唾液中薬物濃度を新たな指標とする非侵襲的抗MRSA薬TDMの創出Principal Investigator
- Principal Investigator
  
  山本善裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  University of Toyama
Clinical pharmacometrics based on combining maturation and artificial intelligence
- Principal Investigator
  
  TSUJI Yasuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nihon University
New anti-MRSA drug optimal treatment strategy with Physiologically-based Pharmacokinetics/ PharmacodynamicsPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Yoshihiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  University of Toyama
Construction of a comprehensive sepsis testing system based on the new sepsis definition and its operational deployment in Japan and Southeast Asia.
- Principal Investigator
  
  Kitajima Isao
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  University of Toyama
Development of antimicrobial chemotherapy based on clinical pharmacometrics and maturation
- Principal Investigator
  
  TSUJI Yasuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nihon University
  University of Toyama

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Population Pharmacokinetic Model for Unbound Concentrations of Daptomycin in Patients with MRSA Including Patients Undergoing Hemodialysis2023
- Author(s)
  Takahashi Saki、Tsuji Yasuhiro、Holford Nick、Ogami Chika、Kasai Hidefumi、Kawasuji Hitoshi、To Hideto、Yamamoto Yoshihiro
- Journal Title
  
  European Journal of Drug Metabolism and Pharmacokinetics
  
  Volume: 48 Issue: 2 Pages: 201-211
- DOI
  10.1007/s13318-023-00820-0
- Data Source
  KAKENHI-PROJECT-20K07189
[Journal Article] Implementation Degree Assessment Sheet for Health Program in Japan by Customizing CFIR: Development and Validation2022
- Author(s)
  Okamoto Reiko、Kageyama Masako、Koide Keiko、Tanaka Miho、Yamamoto Yoshiko、Fujioka Mana、Osuna Ayami、Saeki Kazuko、Hirokane Kazue、Nagano Fusami、Takemura Shinji
- Journal Title
  
  Implementation Science Communications
  
  Volume: 3 Issue: 1
- DOI
  10.1186/s43058-022-00270-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-19H03961
[Journal Article] Classification Tree Analysis Based On Machine Learning for Predicting Linezolid-Induced Thrombocytopenia2021
- Author(s)
  Takahashi Saki、Tsuji Yasuhiro、Kasai Hidefumi、Ogami Chika、Kawasuji Hitoshi、Yamamoto Yoshihiro、To Hideto
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: － Issue: 5 Pages: 2295-2300
- DOI
  10.1016/j.xphs.2021.02.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07189, KAKENHI-PROJECT-19K08950
[Journal Article] External Evaluation of Population Pharmacokinetics and Pharmacodynamics in Linezolid-Induced Thrombocytopenia: The Transferability of Published Models to Different Hospitalized Patients2021
- Author(s)
  Ogami Chika、Tsuji Yasuhiro、Nishi Yoshifumi、Kawasuji Hitoshi、To Hideto、Yamamoto Yoshihiro
- Journal Title
  
  Therapeutic Drug Monitoring
  
  Volume: 43 Issue: 2 Pages: 271-278
- DOI
  10.1097/ftd.0000000000000816
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J23248, KAKENHI-PROJECT-19K08950, KAKENHI-PROJECT-20K07189
[Journal Article] Development of a simple method for measuring tedizolid concentration in human serum using HPLC with a fluorescent detector2021
- Author(s)
  Tsuji Yasuhiro、Numajiri Miki、Ogami Chika、Kurosaki Fumihiro、Miyamoto Aoi、Aoyama Takahiko、Kawasuji Hitoshi、Nagaoka Kentaro、Matsumoto Yoshiaki、To Hideto、Yamamoto Yoshihiro
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 49 Pages: e28127-e28127
- DOI
  10.1097/md.0000000000028127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08950, KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-20K07189
[Journal Article] Increased cerebrospinal fluid adenosine 5'-triphosphate in patients with amyotrophic lateral sclerosis2021
- Author(s)
  Nukui Takamasa、Matsui Atsushi、Niimi Hideki、Sugimoto Tomoyuki、Hayashi Tomohiro、Dougu Nobuhiro、Konishi Hirofumi、Yamamoto Mamoru、Anada Ryoko、Matsuda Noriyuki、Kitajima Isao、Nakatsuji Yuji
- Journal Title
  
  BMC Neurology
  
  Volume: 21 Issue: 1 Pages: 1-8
- DOI
  10.1186/s12883-021-02288-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-21K11165, KAKENHI-PROJECT-23K21403
[Journal Article] Initially Reduced Linezolid Dosing Regimen to Prevent Thrombocytopenia in Hemodialysis Patients2021
- Author(s)
  Kawasuji Hitoshi、Tsuji Yasuhiro、Ogami Chika、Kaneda Makito、Murai Yushi、Kimoto Kou、Ueno Akitoshi、Miyajima Yuki、Fukui Yasutaka、Sakamaki Ippei、Yamamoto Yoshihiro
- Journal Title
  
  Antibiotics
  
  Volume: 10 Issue: 5 Pages: 496-496
- DOI
  10.3390/antibiotics10050496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08950
[Journal Article] Sitafloxacin reduces tumor necrosis factor alpha (TNFα) converting enzyme (TACE) phosphorylation and activity to inhibit TNFα release from lipopolysaccharide-stimulated THP-1 cells2021
- Author(s)
  Sakamaki Ippei、Fukushi Michika、Ohashi Wakana、Tanaka Yukie、Itoh Kazuhiro、Tomihara Kei、Yamamoto Yoshihiro、Iwasaki Hiromichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-03511-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-21K08488
[Journal Article] Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients2021
- Author(s)
  Kawasuji Hitoshi、Tsuji Yasuhiro、Ogami Chika、Kimoto Kou、Ueno Akitoshi、Miyajima Yuki、Kawago Koyomi、Sakamaki Ippei、Yamamoto Yoshihiro
- Journal Title
  
  BMC Pharmacology and Toxicology
  
  Volume: 22 Issue: 1
- DOI
  10.1186/s40360-021-00479-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08950, KAKENHI-PROJECT-20K07189
[Journal Article] Evaluation of a novel urinary antigen test kit for diagnosing Legionella pneumonia2021
- Author(s)
  Ito Akihiro、Yamamoto Yoshihiro、Ishii Yoshikazu、Takeda Hiroaki、Higa Futoshi、Miyara Takayuki、Saito Keisuke、Ishikawa Takeo、Ishida Tadashi、Tateda Kazuhiro
- Journal Title
  
  International Journal of Infectious Diseases
  
  Volume: 103 Pages: 42-47
- DOI
  10.1016/j.ijid.2020.10.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02728
[Journal Article] Evaluation of the relationship between linezolid exposure and hyponatremia2021
- Author(s)
  Nishi Yoshifumi、Ogami Chika、Tsuji Yasuhiro、Kawasuji Hitoshi、Yamada Harumi、Kawai Shin、Sakamaki Ippei、To Hideto、Yamamoto Yoshihiro
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 27 Issue: 2 Pages: 165-171
- DOI
  10.1016/j.jiac.2020.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08950, KAKENHI-PROJECT-20K07189, KAKENHI-PROJECT-18J23248
[Journal Article] A case of COVID-19 diagnosed with favipiravir-induced drug fever based on a positive drug-induced lymphocyte stimulation test2021
- Author(s)
  Murai Yushi、Kawasuji Hitoshi、Takegoshi Yusuke、Kaneda Makito、Kimoto Kou、Ueno Akitoshi、Miyajima Yuki、Kawago Koyomi、Fukui Yasutaka、Ogami Chika、Sakamaki Ippei、Tsuji Yasuhiro、Morinaga Yoshitomo、Yamamoto Yoshihiro
- Journal Title
  
  International Journal of Infectious Diseases
  
  Volume: 106 Pages: 33-35
- DOI
  10.1016/j.ijid.2021.03.048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07189
[Journal Article] Novel and potent antimicrobial effects of caspofungin on drug-resistant Candida and bacteria2020
- Author(s)
  Sumiyoshi Makoto、Miyazaki Taiga、Makau Juliann Nzembi、Mizuta Satoshi、Tanaka Yoshimasa、Ishikawa Takeshi、Makimura Koichi、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 17745-17745
- DOI
  10.1038/s41598-020-74749-8
- NAID
  120006988489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07540, KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-17K09618, KAKENHI-PROJECT-18K11536, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-20K08543
[Journal Article] Bacteremia caused by Slackia exigua: A report of two cases and literature review2020
- Author(s)
  Kawasuji Hitoshi、Kaya Hiroyasu、Kawamura Takayuki、Ueno Akitoshi、Miyajima Yuki、Tsuda Takeshi、Taniguchi Hirokazu、Nakamura Masahiko、Wada Akinori、Sakamaki Ippei、Niimi Hideki、Yamamoto Yoshihiro
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 26 Issue: 1 Pages: 119-123
- DOI
  10.1016/j.jiac.2019.06.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02728
[Journal Article] Pharmacokinetics and pharmacodynamics of daptomycin in a clinical setting2020
- Author(s)
  Tsukada Hiroko、Tsuji Yasuhiro、Yamashina Takuya、Tsuruta Minako、Hiraki Yoichi、Tsuruyama Moeko、Ogami Chika、Kawasuji Hitoshi、Sakamaki Ippei、Yamamoto Yoshihiro
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 26 Issue: 2 Pages: 230-235
- DOI
  10.1016/j.jiac.2019.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08950, KAKENHI-PROJECT-18J23248, KAKENHI-PROJECT-17K08438
[Journal Article] Rapid Identification of Candida Species in Candidemia Directly from Blood Samples Using Imperfect Match Probes2020
- Author(s)
  Higashi Yoshitsugu、Niimi Hideki、Sakamaki Ippei、Yamamoto Yoshihiro、Kitajima Isao
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-62276-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02728
[Journal Article] Positive infectious disease consultation at the time of blood culture collection is assosiated with decreased mortality in patients with methicillin-resistant Staphylococcus aureus bacteremia: A retrospective cohort study.2020
- Author(s)
  Kawasuji H, Sakamaki I, Kawamura T, Ueno A, Miyajima Y, Matsumoto K, Kawago K, Higashi Y, Yamamoto Y.
- Journal Title
  
  J Infect Chemother
  
  Volume: - Issue: 6 Pages: 588-595
- DOI
  10.1016/j.jiac.2020.01.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-19K08950
[Journal Article] Discrepancies in preferences regarding the care of terminal-phase pneumonia in elderly patients among patients, families, and doctors: A multicenter questionnaire survey in nagasaki, Japan2020
- Author(s)
  Takazono Takahiro、Imamura Yoshifumi、Kawakami Kaoru、Yamasaki Naoya、Shimizu Hiroyoshi、Usuki Katsuhiro、Kiyohara Maiko、Hirayama Tatsuro、Tashiro Masato、Hosogaya Naoki、Saijo Tomomi、Yamamoto Kazuko、Miyazaki Taiga、Yanagihara Katsunori、Izumikawa Koichi、Mukae Hiroshi
- Journal Title
  
  Respiratory Investigation
  
  Volume: 58 Issue: 6 Pages: 488-494
- DOI
  10.1016/j.resinv.2020.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02728
[Journal Article] Cerebrospinal fluid ATP as a potential biomarker in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke like episodes (MELAS)2020
- Author(s)
  Nukui Takamasa、Matsui Atsushi、Niimi Hideki、Yamamoto Mamoru、Matsuda Noriyuki、Piao Jin-Lan、Noguchi Kyo、Kitajima Isao、Nakatsuji Yuji
- Journal Title
  
  Mitochondrion
  
  Volume: 50 Pages: 145-148
- DOI
  10.1016/j.mito.2019.11.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02728, KAKENHI-PROJECT-18K10743
[Journal Article] Pharmacokinetics, toxicity and clinical efficacy of linezolid in Japanese pediatric patients.2019
- Author(s)
  Ogami C, Tsuji Y, To H, Yamamoto Y
- Journal Title
  
  J Infect Chemother
  
  Volume: 25(12) Pages: 979-986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02728
[Journal Article] Pharmacokinetics, toxicity and clinical efficacy of linezolid in Japanese pediatric patients2019
- Author(s)
  Ogami Chika、Tsuji Yasuhiro、To Hideto、Yamamoto Yoshihiro
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 25 Issue: 12 Pages: 979-986
- DOI
  10.1016/j.jiac.2019.05.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08950, KAKENHI-PROJECT-18J23248, KAKENHI-PROJECT-17K08438
[Journal Article] Effects of a rifampicin pre-treatment on linezolid pharmacokinetics2019
- Author(s)
  Okazaki Fumiyasu、Tsuji Yasuhiro、Seto Yoshihiro、Ogami Chika、Yamamoto Yoshihiro、To Hideto
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 9 Pages: e0214037-e0214037
- DOI
  10.1371/journal.pone.0214037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08950, KAKENHI-PROJECT-18J23248, KAKENHI-PROJECT-17K08438
[Journal Article] Population pharmacokinetics of teicoplanin in hospitalized elderly patients using cystatin C as an indicator of renal function2018
- Author(s)
  Kasai Hidefumi、Tsuji Yasuhiro、hiraki Yoichi、Tsuruyama Moeko、To Hideto、Yamamoto Yoshihiro
- Journal Title
  
  J Infect Chemother
  
  Volume: 24 Issue: 4 Pages: 284-291
- DOI
  10.1016/j.jiac.2017.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] 抗菌薬リネゾリドのTDM実用化に向けた薬物血中濃度クロスバリデーション試験の試み2023
- Author(s)
  辻泰弘、矢作彩、櫻井里咲、栗原絵、奥田詩織、川筋仁史、青山隆彦、山本善裕
- Organizer
  第33回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-22K08597
[Presentation] MRSA菌血症に対するバンコマイシン、テイコプラニン、ダプトマイシンと比較したリネゾリドの有効性及び安全性の評価：システマティックレビュー及びメタ解析2023
- Author(s)
  川筋仁史、辻泰弘、江嵜真佳、腰山裕貴、竹腰雄祐、兼田磨熙杜、村井佑至、木本鴻、長岡健太郎、山本善裕、唐牛春香、光武耕太郎
- Organizer
  MRSAフォーラム2023
- Data Source
  KAKENHI-PROJECT-22K08597
[Presentation] 唾液中薬物濃度モニタリング（STDM）創出に向けた血清中および唾液中リネゾリド濃度の相関性検証2023
- Author(s)
  兼田磨熙杜、辻泰弘、川筋仁史、竹腰雄祐、木本鴻、上野亨敏、宮嶋友希、長岡健太郎、山本善裕
- Organizer
  第71回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-22K08597
[Presentation] 極低薬物濃度域を測定可能としたテジゾリドの薬物血中濃度解析2022
- Author(s)
  辻　泰弘，沼尻美樹，板井　彩，奥田詩織，尾上知佳，川筋仁史，長岡健太郎，藤　秀人，山本善裕．
- Organizer
  MRSAフォーラム2022
- Data Source
  KAKENHI-PROJECT-22K08597
[Presentation] 非透析腎機能障害者におけるリネゾリド初期投与量および維持投与量の検討2022
- Author(s)
  川筋仁史，辻　泰弘，安河内励，竹腰雄祐，兼田磨熙杜，上野亨敏，宮嶋友希，河合暦美, 酒巻一平，山本善裕
- Organizer
  第69回日本化学療法学会西日本支部総会
- Data Source
  KAKENHI-PROJECT-22K08597
[Presentation] 低ナトリウム血症におけるリネゾリドの暴露と患者背景の関連性の評価2021
- Author(s)
  西　圭史，辻　泰弘，尾上知佳，吉田博昭，倉井大輔，河合　伸，川筋仁史、山本善裕
- Organizer
  第95回日本感染症学会学術講演会・第69回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] 簡便かつ低濃度域まで測定可能なテジゾリド薬物濃度定量法の開発2021
- Author(s)
  辻泰弘、尾上知佳、川筋仁史、長岡健太郎、山本善裕
- Organizer
  第68回日本化学療法学会東日本支部総会
- Data Source
  KAKENHI-PROJECT-20K07189
[Presentation] 腎機能障害者におけるリネゾリド初期投与および維持投与量の検討2021
- Author(s)
  川筋仁史，安河内励，辻　泰弘，尾上知佳，竹腰雄祐，兼田磨熙杜，村井佑至，木本　鴻，上野亨敏，宮嶋友希，河合暦美, 福井康貴，酒巻一平，山本善裕
- Organizer
  MRSAフォーラム2020 in OSAKA
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] リネゾリド個別化治療に向けたearly-TDMの必要性―機械学習による目標濃度・治療介入日の探索―2021
- Author(s)
  辻泰弘、高橋早紀、尾上知佳、川筋仁史、藤秀人、山本善裕
- Organizer
  MRSAフォーラム2021
- Data Source
  KAKENHI-PROJECT-20K07189
[Presentation] Classification tree analysis based on machine learning for predicting linezolid-induced thrombocytopenia2021
- Author(s)
  Takahashi S, Tsuji Y, Ogami C, Kasai H, Kawasuji H, Yamamoto Y, To H
- Organizer
  3rd Asian Pharmacometrics Network (APN) Symposium 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07189
[Presentation] 簡便かつ低濃度域まで測定可能なテジゾリド薬物濃度定量法の開発2021
- Author(s)
  辻　泰弘，尾上知佳，川筋仁史，長岡健太郎，山本善裕
- Organizer
  第68回日本化学療法学会東日本支部総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] 機械学習に基づくリネゾリド誘発性血小板減少症の予測2021
- Author(s)
  高橋早紀、辻泰弘、笠井英史、尾上知佳、川筋仁史、山本善裕、藤秀人
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-20K07189
[Presentation] COVID-19感染患者における血中Favipiravir濃度の個体間変動2021
- Author(s)
  辻泰弘、尾上知佳、川筋仁史、山本善裕
- Organizer
  第69回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-20K07189
[Presentation] 非透析腎機能障害者におけるリネゾリド初期投与量および維持投与量の検討2021
- Author(s)
  川筋仁史，辻　泰弘，安河内励，竹腰雄祐，兼田磨熙杜，上野亨敏，宮嶋友希，河合暦美, 酒巻一平，山本善裕
- Organizer
  第69回日本化学療法学会西日本支部総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] リネゾリド個別化治療に向けたearly-TDMの必要性～機械学習による目標濃度・治療介入日の探索～2021
- Author(s)
  辻　泰弘，高橋早紀，尾上知佳，川筋仁史，長岡健太郎，藤　秀人，山本善裕
- Organizer
  MRSAフォーラム2020 in OSAKA
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] 腎機能障害者におけるリネゾリド初期投与および維持投与量の検討2021
- Author(s)
  川筋仁史、安河内励、辻泰弘、尾上知佳、竹腰雄祐、兼田磨熙杜、村井佑至、木本鴻、上野亨敏、宮嶋友希、河合暦美、福井康貴、酒巻一平、山本善裕
- Organizer
  MRSAフォーラム2021
- Data Source
  KAKENHI-PROJECT-20K07189
[Presentation] リネゾリドの母集団PK/PDモデルの外部評価および投与設計支援ソフトウェアPycsimの開発2020
- Author(s)
  尾上知佳、辻泰弘、西圭史、山本善裕、藤秀人
- Organizer
  第41回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07189
[Presentation] 腎機能障害者におけるリネゾリド初期投与量の検討2020
- Author(s)
  川筋仁史，辻　泰弘，上野亨敏，宮嶋友希，河合暦美，酒巻一平，山本善裕
- Organizer
  第68回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] リネゾリドPK/PDモデルの外部評価および投与設計支援ソフトウェアPycsimの開発2020
- Author(s)
  尾上知佳，辻　泰弘，西　圭史，山本善裕
- Organizer
  第67回日本化学療法学会東日本支部総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] 教育講演「わかりやすい抗MRSA薬の使い方」2020
- Author(s)
  山本善裕
- Organizer
  第68回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] 非透析腎機能障害者におけるリネゾリド初期投与量および維持投与量の検討2020
- Author(s)
  川筋仁史，辻　泰弘，安河内励，竹腰雄祐，兼田磨熙杜，上野亨敏，宮嶋友希，河合暦美, 酒巻一平，山本善裕
- Organizer
  第68回日本化学療法学会西日本支部総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] 抗MRSA薬の位置づけと使い分け「対オキサゾリジノン系派」2019
- Author(s)
  山本善裕
- Organizer
  MRSAフォーラム2019
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] 機械学習とModel Based Exposure-Response解析によるリネゾリド誘発性血小板減少予測モデルの検討2019
- Author(s)
  高橋早紀、辻泰弘、尾上知佳、中舘成河、松本宜明、藤秀人、山本善裕
- Organizer
  第40回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] カンジダ血症における起炎菌迅速同定検査法の確立2019
- Author(s)
  仁井見英樹、東祥嗣、酒巻一平、山本善裕、北島勲
- Organizer
  第59回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02728
[Presentation] 機械学習とModel Based Exposure-Response解析によるリネゾリド誘発性血小板減少予測モデルの検討2019
- Author(s)
  川村早紀，辻　泰弘，尾上知佳，中館成河，松本宣明，藤　秀人，山本善裕
- Organizer
  第40回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] 抗MRSA薬TDM支援ソフトMr. TDMの開発2019
- Author(s)
  酒巻一平，川村隆之，川筋仁史，宮嶋友希，河合暦美, 辻　泰弘, 山本善裕
- Organizer
  第67回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] MRSA菌血症診療におけるActive Consultationの有用性の検討2019
- Author(s)
  川筋仁史，上野亨敏，宮嶋友希，河合暦美, 酒巻一平，山本善裕
- Organizer
  第62回日本感染症学会中日本地方会学術集会
- Data Source
  KAKENHI-PROJECT-19K08950
[Presentation] MRSAアウトブレイク発生時の院内感染対策にPOT法が有効であった事例。2019
- Author(s)
  1)杉江和茂、関口敬文、森田未香、坂本純子、上野智浩、酒巻一平、山本善裕、仁井見英樹、北島勲
- Organizer
  第30回日本臨床微生物学会総会学術集会
- Data Source
  KAKENHI-PROJECT-18H02728
[Presentation] 日常診療下におけるダプトマイシンのPK-PDパラメータへの達成率2019
- Author(s)
  川野智美、小田原真希、山科卓也、塚田寛子、行徳和雅子、松本沙織、藤本友希、横山知美、川井田知広、鶴山萌子、辻泰弘、尾上知佳、山本善裕、平木洋一
- Organizer
  第29回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] 富山県下26施設における抗菌薬使用量と耐性菌分離率に関する地域共同サーベイランス2018
- Author(s)
  細野美幸、飯尾志帆、高野雄介、高橋慎太郎、脇田真之、守内匡、加藤貴子、窪田佳代子、杉田真理子、船本哲生、辻泰弘、山本善裕
- Organizer
  第28回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] Novel rapid quantification method of bacteria in a septic blood sample can produce an effective biomarker for monitoring patient care.2018
- Author(s)
  Niimi H, Higashi Y, Ueno T, Mori M, Yamamoto Y, Saito S, Kitajima I
- Organizer
  70th AACC Annual Scientific Meeting & Clinical Lab Expo.2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02728
[Presentation] リネゾリド投与におけるTDM実施の推進を目的としたPKPD解析2018
- Author(s)
  尾上知佳、辻泰弘、中舘成河、藤秀人、山本善裕
- Organizer
  日本医療薬学会第2回フレッシャーズ・カンファレンス
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] Population pharmacokinetics of unbound daptomycin in hospital patients with Gram-positive infections2018
- Author(s)
  Ogami C, Tsuji Y, Holford N, Kasai H, To H, Yamamoto Y
- Organizer
  PAGE 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] 数を敗血症の新規バイオマーカーとする起炎菌迅速同定・定量検査法の開発2018
- Author(s)
  仁井見英樹、東祥嗣、上野智浩、山本善裕、北島勲
- Organizer
  第65回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02728
[Presentation] リネゾリドの治療薬物モニタリング実施を支援する投与設計およびノモグラムの開発2018
- Author(s)
  尾上知佳、辻泰弘、山本善裕
- Organizer
  第66回日本化学療法学会西日本支部総会
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] Population pharmacokinetics of unbound daptomycin in hospital patients with Gram-positive infections2018
- Author(s)
  Ogami C, Tsuji Y, Holford N, Kasai H, To H, Yamamoto Y
- Organizer
  Population Approach Group in Europe (PAGE) 2018 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] 抗MRSA薬TDM支援ソフトMr.TDMの開発および有用性の検討2018
- Author(s)
  酒巻一平、川村隆之、木谷健人、上野亭敏、川筋仁史、宮嶋友希、松本かおる、河合暦美、東祥嗣、辻泰弘、山本善裕
- Organizer
  MRSAフォーラム2018
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] 新規抗MRSA薬TDM支援ソフトの開発および有用性の検討2018
- Author(s)
  酒巻一平、川村隆之、木谷健人、上野亨敏、川筋仁史、宮嶋友希、河合暦美、東祥嗣、辻泰弘、山本善裕
- Organizer
  第66回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-17K08438
[Presentation] Instability of daptomycin in serum at various temperatures may affect its pharmacokinetics2017
- Author(s)
  Ogami C, Tsuji Y, Kasai H, Yamamoto Y, Matsunaga K, Karube Y, To H
- Organizer
  30th ICC 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08438

1. TSUJI Yasuhiro (20644339)

# of Collaborated Projects: 5 results

# of Collaborated Products: 43 results
2. 仁井見英樹 (50401865)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. Kitajima Isao (50214797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 原田健右 (30436795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 柳原克紀 (40315239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 松本宜明 (10199896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 藤井努 (60566967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中晴祥 (80793504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamamoto Yoshihiro 山本 善裕

YAMAMOTO Yoshihiro 山本 善裕

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タンパク質結合理論を基盤とした薬効直結型の抗MRSA薬TDM手法の開発Principal Investigator

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膵頭十二指腸切除周術期に複合的迅速微生物検査を応用した新たな抗菌治療戦略の構築

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唾液中薬物濃度を新たな指標とする非侵襲的抗MRSA薬TDMの創出Principal Investigator

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Clinical pharmacometrics based on combining maturation and artificial intelligence

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New anti-MRSA drug optimal treatment strategy with Physiologically-based Pharmacokinetics/ PharmacodynamicsPrincipal Investigator

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Construction of a comprehensive sepsis testing system based on the new sepsis definition and its operational deployment in Japan and Southeast Asia.

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Development of antimicrobial chemotherapy based on clinical pharmacometrics and maturation

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[Journal Article] Population Pharmacokinetic Model for Unbound Concentrations of Daptomycin in Patients with MRSA Including Patients Undergoing Hemodialysis2023

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[Journal Article] Implementation Degree Assessment Sheet for Health Program in Japan by Customizing CFIR: Development and Validation2022

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[Journal Article] Classification Tree Analysis Based On Machine Learning for Predicting Linezolid-Induced Thrombocytopenia2021

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[Journal Article] External Evaluation of Population Pharmacokinetics and Pharmacodynamics in Linezolid-Induced Thrombocytopenia: The Transferability of Published Models to Different Hospitalized Patients2021

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[Journal Article] Development of a simple method for measuring tedizolid concentration in human serum using HPLC with a fluorescent detector2021

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[Journal Article] Increased cerebrospinal fluid adenosine 5'-triphosphate in patients with amyotrophic lateral sclerosis2021

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[Journal Article] Initially Reduced Linezolid Dosing Regimen to Prevent Thrombocytopenia in Hemodialysis Patients2021

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Yamamoto Yoshihiro 山本善裕

YAMAMOTO Yoshihiro 山本善裕