Kawamoto Yasuhiro 河本恭裕

… Alternative Names

KAWAMOTO Yasuhiro 河本恭裕

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Researcher Number	40335253
Affiliation (Current)	2025: 京都大学, 医学研究科, 非常勤講師
Affiliation (based on the past Project Information) *help	2015: 京都大学, 医学研究科, 非常勤講師 2013 – 2014: 京都大学, 医学(系)研究科(研究院), その他 2011 – 2012: 京都大学, 医学(系)研究科(研究院), 非常勤講師 2009 – 2012: 京都大学, 医学研究科, 非常勤講師 2003 – 2005: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Neurology Except Principal Investigator Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology
Keywords	Principal Investigator α-synuclein / パーキンソン病 / molecular chaperones / astrocytes / immunohistochemistry / Lewy body-like hyaline inclusins / glial cytoplsmic inclusions / Lewy bodies / 14-3-3 proteins / 脱髄疾患 … More / リン酸化タウ / 免疫組織化学法 / クロイツフェルト・ヤコブ病 / 筋萎縮性側索硬化症 / 多系統萎縮症 / 分子シャペロン / アストロサイト / 免疫組織化学 / Lewy小体様硝子様封入体 / グリア細胞質内封入体 / Lewy小体 / αシヌクレイン / 14-3-3蛋白 / parkin / XIAP / アポトーシス / ミトコンドリア / Omi/HtrA2 … More Except Principal Investigator NF-кB / 炎症性サイトカイン / ゴルジ装置断片化 / NF-κB / 筋萎縮性側索硬化症 / オプチニューリン / Parkinson' s disease / Parkinson's disease / Parkinson' sdisease / ノックアウトマウス / knockout mouse / HtrA2 / パーキンソン病 Less

Investigation of pathomechanism and novel therapeutic strategy for ALS on the basis of optineurin dysfunction
- Principal Investigator
  
  Ito Hidefumi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Wakayama Medical University
Research on the role of Omi/HtrA2 in the abnormal mitochondria in patients with Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  KAWAMOTO Yasuhiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
Biochemical and neuropathological analysis of HtrA2 knockout mouse
- Principal Investigator
  
  ITO Hidefumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
the role of molecular chaperones in α-synuclein-related diseasesPrincipal Investigator
- Principal Investigator
  
  KAWAMOTO Yasuhiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University

All 2014 2013 2012 2011 2010 2009 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] XIAP immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy.2014
- Author(s)
  Kawamoto Y, Ito H, Ihara M, Takahashi R.
- Journal Title
  
  Clin Neuropathol.
  
  Volume: 33(1) Issue: 01 Pages: 76-83
- DOI
  10.5414/np300610
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-24300132
[Journal Article] Immunohistochemical localization of apoptosome-related proteins in Lewy bodies in Parkinson's disease and dementia with Lewy bodies.2014
- Author(s)
  Kawamoto Y, Ito H, Ayaki T, Takahashi R.
- Journal Title
  
  Brain Res.
  
  Volume: 1571 Pages: 39-48
- DOI
  10.1016/j.brainres.2014.05.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300132
[Journal Article] XIAP immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy2013
- Author(s)
  Y. Kawamoto
- Journal Title
  
  Clinical Neuropathology (in press)
  
  Volume: undecicided
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590930
[Journal Article] Immunohistochemical localization of X-linked inhibitor of apoptosis protein in brainstem-type and cortical Lewy bodies2012
- Author(s)
  Kawamoto Y, Ito H, Ihara M, Takahashi R
- Journal Title
  
  NeuroReport
  
  Volume: 23:162-167 Issue: 3 Pages: 162-167
- DOI
  10.1097/wnr.0b013e32834f4066
- NAID
  120005244628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590930
[Journal Article] Co localization of 14-3-3 proteins with SOD1 in Lewy Body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model2011
- Author(s)
  Okamoto Y, Shirakashi Y, Ihara M, Urushitani M, Oono M, Kawamoto Y, Yamashita H, Shimohama S, Kato S, Hirano A, Tomimoto H, Ito H, Takahashi R
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 5 Pages: e20427-e20427
- DOI
  10.1371/journal.pone.0020427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930, KAKENHI-PROJECT-22659171, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] An autopsy case of SOD1-related ALS with TDP-43 positive inclusions2011
- Author(s)
  Okamoto Y, Ihara M, Urushitani M, Yamashita H, Kondo T, Tanigaki A, Oono M, Kawamata J, Ikemoto A, Kawamoto Y, Takahashi R, Ito H
- Journal Title
  
  Neurology
  
  Volume: 77:1993-1995 Issue: 22 Pages: 1993-1995
- DOI
  10.1212/wnl.0b013e31823a0cfc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590930, KAKENHI-PROJECT-22659171, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Localization of HtrA2/Omi immunoreactivity in brains affected by Alzheimer's disease2010
- Author(s)
  Y.Kawamoto, et al.
- Journal Title
  
  NeuroReport
  
  Volume: 21 Pages: 1121-1125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590930
[Journal Article] HtrA2/Omi immunoreactive neuronal inclusions in the anterior horn of patients with sporadic and Cu/Zn superoxide dismutase(SOD1)mutant amyotrophic lateral sclerosis2010
- Author(s)
  Y.Kawamoto, et al.
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: 36 Pages: 331-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590930
[Journal Article] HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn of patients with sporadic and SOD1 mutant amyotrophic lateral sclerosis2010
- Author(s)
  Kawamoto Y, Ito H, Kobayashi Y, Suzuki Y, Akiguchi I, Fujimura H, Sakoda S, Kusaka H, Hirano A, Takahashi R
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: 36 Issue: 4 Pages: 331-344
- DOI
  10.1111/j.1365-2990.2010.01075.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930
[Journal Article] HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn of patients with sporadic and SOD1 mutant amyotrophic lateral sclerosis.2010
- Author(s)
  Kawamoto Y, et al
- Journal Title
  
  Neuropathol Appl Neurobiol. 36(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336
[Journal Article] Localization of HtrA2/Omi immunoreactivity in brains with Alzheimer's disease2010
- Author(s)
  Kawamoto Y, Ito H, Ihara M, Kobayashi Y, Suzuki Y, Takahashi R
- Journal Title
  
  Neuroreport
  
  Volume: 21 Issue: 17 Pages: 1121-1125
- DOI
  10.1097/wnr.0b013e328340a731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930
[Journal Article] Localization of HtrA2/Omi immunoreactivity, in brains with Alzheimers sdisease.2010
- Author(s)
  Kawamoto Y, Ito H, et al
- Journal Title
  
  Neuroreport
  
  Volume: 21 Pages: 1121-1125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336
[Journal Article] Upregulated expression of 14-3-3 proteins in astrocytes from human cerebrovascular ischemic lesions2006
- Author(s)
  Y.Kawamoto
- Journal Title
  
  Stroke 37・3
  
  Pages: 830-835
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] Upregulated expression of 14-3-3 proteins in astrocytes from human cerebrovascular ischemic lesions.2006
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Stroke 37
  
  Pages: 830-835
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] 14-3-3 proteins in Lewy body-like hyaline inclusions in a patients with a two-base pair deletion in the Cu/Zn superoxide dismutaze (SOD1) gene2005
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Nueropathologica 110
  
  Pages: 203-204
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] 14-3-3 proteins in Lewy body-like hyaline inclusions in a patient with familial amyotrophic lateral saclerosis with a two-base pair deletion in the Cu/Zn superoxide dismutase (SOD1) gene2005
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Neuropathol 110・2
  
  Pages: 203-204
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] 14-3-3 proteins in Lewy body-like in a patients with a two-base pair deletion in the Cu/Zn superoxide dismutaze (SOD1) gene2005
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Neuropathologica 110
  
  Pages: 203-204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] Enhanced expression of 14-3-3 proteins in reactive astrocytes in Creutzfeldt-Jakob disease brains2004
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Nueropathologica 108
  
  Pages: 302-308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] Enhanced expression of 14-3-3 proteins In reactive astrocytes in Creutzfeldt-Jakob disease brains2004
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Neuropatholica 108
  
  Pages: 302-308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] 14-3-3 proteins in Lewy body-like hyaline inclusions in patients with sporadic amyotrophic lateral sclerosis2004
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta neuropathologica 108
  
  Pages: 531-537
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] 14-3-3 proteins in Lewy body-like hyaline inclusions in patients with sporadic amyotrophic lateral sclerosis2004
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Nueropathologica 108
  
  Pages: 531-537
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] Increased 14-3-3 immunoreactivity in glial elements in patients with multiple sclerosis2004
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Neuropathologica 107
  
  Pages: 137-143
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] Increased 14-3-3 immunoreactivity in glial elements in patients with multiple sclerosis2004
- Author(s)
  Kawamoto et al.
- Journal Title
  
  Acta Nueropathologica 107
  
  Pages: 137-143
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] Enhanced expression of 14-3-3 proteins in reactive astrocytes in Creutzfeldt-Jakob disease brains2004
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Neuropathologica 108・4
  
  Pages: 302-308
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] 14-3-3 proteins in Lewy body-like hyaline inclusions in patients with sporadic amyotrophic lateral sclerosis2004
- Author(s)
  Y.Kawamoto et al.
- Journal Title
  
  Acta Neuropathologica 108・6
  
  Pages: 531-537
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] XIAP immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy
- Author(s)
  Kawamoto Y, Ito H, Ihara M, Takahashi R
- Journal Title
  
  Clinical Neuropathology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] αシヌクレイノパチーにおけるアポトーシス関連タンパク質の免疫組織化学的検討2014
- Author(s)
  河本恭裕, 綾木孝, 漆谷真, 伊東秀文, 高橋良輔
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際センター
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-24300132
[Presentation] パーキンソン病患者の中脳黒質のLewy小体におけるapoptosome関連タンパク質の集積2013
- Author(s)
  河本恭裕
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2013-06-01
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] 多系統萎縮症患者脳内の封入体におけるXIAPの蓄積2012
- Author(s)
  河本恭裕
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] 脳幹型および皮質型Lewy小体におけるXIAPとHtrA2/Omiの共存2011
- Author(s)
  河本恭裕、伊東秀文, 他
- Organizer
  第52回日本神経学会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21500336
[Presentation] 脳幹型および皮質型Lewy小体におけるXIAPとHtrA2/Omiの共存2011
- Author(s)
  河本恭裕
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] Alzheimer病患者脳内におけるHtrA2/Omiの免疫組織化学的検討2011
- Author(s)
  河本恭裕、伊東秀文, (2名略)、高橋良輔
- Organizer
  第52回日本神経病理学会総会
- Place of Presentation
  京都(京都テルサ)
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21500336
[Presentation] Alzheimer病患者脳内におけるHtrA2/Omiの免疫組織化学的検討2011
- Author(s)
  河本恭裕、伊東秀文, 他
- Organizer
  第52回日本神経病理学会
- Place of Presentation
  京都
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21500336
[Presentation] 脳幹型および皮質型Lewy小体におけるXIAPとHtrA2/Omiの共存2011
- Author(s)
  河本恭裕、伊東秀文, (3名略)、高橋良輔
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21500336
[Presentation] Alzheimer病患者脳内におけるHtrA2/Omiの免疫組織化学的検討2011
- Author(s)
  河本恭裕
- Organizer
  第52回日本神経病理学会総会学術研究会
- Place of Presentation
  京都
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] Alzheimer病患者脳内におけるOmi/HtrA2の免疫組織化学的検討2010
- Author(s)
  河本恭裕
- Organizer
  第51会日本神経学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] Alzheimer病患者脳内におけるOmi/HtrA2の免疫組織化学的検討2010
- Author(s)
  河本恭裕、伊東秀文, 他
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21500336
[Presentation] Alzheimer病患者脳内におけるHtrA2/Omiの免疫組織化学的検討2010
- Author(s)
  河本恭裕
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] Alzheimer病患者脳内におけるOmi/HtrA2の免疫組織化学的検討2010
- Author(s)
  河本恭裕、伊東秀文, 他
- Organizer
  第51回日本神経学会
- Place of Presentation
  東京
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21500336
[Presentation] 筋萎縮性側索硬化症患者の脊髄前角細胞におけるOmi/HtrA2の集積2009
- Author(s)
  河本恭裕, 他
- Organizer
  第50回日本神経病理学会
- Place of Presentation
  高松市
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-21500336
[Presentation] 筋萎縮性側索硬化症患者の脊髄前角細胞におけるOmi/HtrA2の集積2009
- Author(s)
  河本恭裕、伊東秀文, 他
- Organizer
  第50回日本神経病理学会
- Place of Presentation
  高松
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-21500336
[Presentation] 脳幹型および皮質型Lewy小体におけるXIAPとHtrA2/Omiの共存
- Author(s)
  河本恭裕
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] 多系統委縮症患者脳内の封入体におけるXIAPの蓄積
- Author(s)
  河本恭裕
- Organizer
  第53会日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] パーキンソン病患者の中脳黒質のLewy小体におけるapoptosome関連タンパク質の集積
- Author(s)
  河本恭裕
- Organizer
  第54会日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590930
[Presentation] Alzheimer病患者脳内におけるHtrA2/Omiの免疫組織化学的検討
- Author(s)
  河本恭裕
- Organizer
  第52回日本神経病理学会総会学術研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590930

1. TAKAHASHI Ryosuke (90216771)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. ITO Hidefumi (20250061)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. KAWAKAMI HIDESHI (70253060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. AKIGUCHI Ichiro (30115779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kawamoto Yasuhiro 河本 恭裕

KAWAMOTO Yasuhiro 河本 恭裕

Research Projects

Research Products

Co-Researchers

Investigation of pathomechanism and novel therapeutic strategy for ALS on the basis of optineurin dysfunction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the role of Omi/HtrA2 in the abnormal mitochondria in patients with Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biochemical and neuropathological analysis of HtrA2 knockout mouse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

the role of molecular chaperones in α-synuclein-related diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] XIAP immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunohistochemical localization of apoptosome-related proteins in Lewy bodies in Parkinson's disease and dementia with Lewy bodies.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] XIAP immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy2013

Author(s)

Journal Title

Data Source

[Journal Article] Immunohistochemical localization of X-linked inhibitor of apoptosis protein in brainstem-type and cortical Lewy bodies2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Co localization of 14-3-3 proteins with SOD1 in Lewy Body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An autopsy case of SOD1-related ALS with TDP-43 positive inclusions2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Localization of HtrA2/Omi immunoreactivity in brains affected by Alzheimer's disease2010

Author(s)

Journal Title

Data Source

[Journal Article] HtrA2/Omi immunoreactive neuronal inclusions in the anterior horn of patients with sporadic and Cu/Zn superoxide dismutase(SOD1)mutant amyotrophic lateral sclerosis2010

Author(s)

Journal Title

Data Source

[Journal Article] HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn of patients with sporadic and SOD1 mutant amyotrophic lateral sclerosis2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn of patients with sporadic and SOD1 mutant amyotrophic lateral sclerosis.2010

Author(s)

Journal Title

Data Source

[Journal Article] Localization of HtrA2/Omi immunoreactivity in brains with Alzheimer's disease2010

Author(s)

Journal Title

DOI

Kawamoto Yasuhiro 河本恭裕

KAWAMOTO Yasuhiro 河本恭裕