HOSODA HIROSHI 細田洋司

… Alternative Names

HOSODA Hiroshi 細田洋司

細田洋司ホソダヒロシ

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Researcher Number	40359807
Other IDs
Affiliation (Current)	2025: 信州大学, 医学部, 特任教授 2025: 東京慈恵会医科大学, 医学部, 非常勤講師 2025: 国立研究開発法人国立循環器病研究センター, 病院, 客員研究員
Affiliation (based on the past Project Information) *help	2024: 信州大学, 医学部, 特任教授 2022 – 2023: 信州大学, 学術研究院医学系, 准教授 2021 – 2023: 国立研究開発法人国立循環器病研究センター, 研究所, 客員研究員 2015 – 2020: 国立研究開発法人国立循環器病研究センター, 研究所, 室長 2014: 国立循環器病研究センター, 研究所, 室長 … More 2012 – 2014: 独立行政法人国立循環器病研究センター, 研究所, 室長 2010 – 2011: 独立行政法人国立循環器病研究センター, 再生医療部, 室長 2009: National Cardiovascular Center Research Institute, 生化学部, 特任研究員 2004: 京大, 医学(系)研究科(研究院), 助手 2003: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Endocrinology / Basic Section 59020:Sports sciences-related / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Basic Section 52010:General internal medicine-related / Basic Section 52040:Radiological sciences-related / Basic Section 47060:Clinical pharmacy-related / Basic Section 49020:Human pathology-related / Basic Section 47040:Pharmacology-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 52050:Embryonic medicine and pediatrics-related / Endocrinology / Obstetrics and gynecology / Applied pharmacology
Keywords	Principal Investigator 血管内分泌学 / グレリン / リポ蛋白質 / DNAメチル化 / 腫瘍循環器学 / ナトリウム利尿ペプチド / 生理活性 / 再生医学 / 神経科学 / 生理活性ペプチド … More / 胃 / エネルギー代謝 / 脂肪酸修飾 / 生合成 … More Except Principal Investigator iPS細胞 / ヒトiPS細胞 / エクソソーム解析 / 慢性腎疾患 / 腎動脈狭窄症 / 慢性腎臓病 / 酸素代謝 / OガスPET / 腎臓 / ビッグデータ / トランスクリプトーム解析 / 有害事象 / 副作用 / 予防薬 / ChIP-Seq / HAT1 / p300 / Histopathology / Tenascin / Matrix remodeling / Endomyocardial biopsy / Immunohistochemistry / Epigenetics / Onco-cardiology / テネイシン / H3K27ac / Cancer chemotherapy / ヒストン蛋白アセチル化 / p53 / 組織病理学 / 免疫染色 / COVID-19 / 配向性 / 不整脈 / iPS心筋 / 器質的毒性 / ドラッグリポジショニング / 新興感染症 / 機能的毒性 / 成熟化 / iPS / 心筋 / SARS-CoV-2 / ウイルス感染 / ミトコンドリア毒性 / イメージング / ミトコンドリア / パスウエイ解析 / 次世代シークエンス / 感染 / 収縮 / 後遺症 / 新型コロナウイルス / 依存性 / 高脂肪食 / 摂食 / フローサイトメトリー / 重症心不全 / バンコマイシン腎症 / 急性腎障害 / 血管新生因子 / 血管新生分子 / SGLT2阻害薬 / SGLT2 / 低酸素障害 / 糖尿病性腎臓病 / 超音波イメージング / 心臓発生 / マウス / PDE5阻害剤 / 小動物用超音波高解像度イメージング / 心臓成熟 / 胎児心疾患 / 胎盤病理 / 遺伝子発現解析 / 胎児胎盤循環 / 小動物用高解像度超音波イメージングシステム / 心筋成熟 / 先天性心疾患 / 胎児心不全 / ペプチドホルモン / 生体防護 / 放射線 / アポトーシス / 放射線宿酔 / 骨髄抑制 / ラジオイムノアッセイ / 血球障害 / 放射線障害 / グレリン / 低体重出生児 / 周産期 / 心筋梗塞 / 他家移植 / 細胞シート / 卵膜 / 胎児付属物 / 間葉系幹細胞 / 細胞・組織 Less

Elucidation of Mechanisms and Prevention Strategies for Anticancer Drug-Induced Cardiotoxicity
- Principal Investigator
  
  諫田泰成
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  National Institute of Health Sciences
骨格筋の新機能としての老廃物除去機能を解明するPrincipal Investigator
- Principal Investigator
  
  細田洋司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Shinshu University
慢性腎疾患への15O-ガスPETを用いた定量的血流、酸素代謝解析法の臨床応用
- Principal Investigator
  
  福田哲也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Cardiovascular Center Research Institute
血管機能異常による高脂肪食依存性機構の解明
- Principal Investigator
  
  沢村達也
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Shinshu University
Development of mature iPSC cardiomyocytes toward drug development
- Principal Investigator
  
  Kanda Yasunari
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  National Institute of Health Sciences
Clinicopathological Study on Chemotherapy Related Cardiac Dysfunction
- Principal Investigator
  
  Hatakeyama Kinta
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Cardiovascular Center Research Institute
Elucidation of Mechanism of Diabetic Kidney Disease by Focusing on Hypoxia-Inducing Molecules - Approach from SGLT2 Inhibition
- Principal Investigator
  
  Makino Hisashi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  National Cardiovascular Center Research Institute
Fundamental research on the construction of an acute kidney injury warning system and reversibility indicators of renal function in the area of severe heart failure.
- Principal Investigator
  
  Yoshihara Fumiki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  National Cardiovascular Center Research Institute
The role of DNA methylation in anticancer drug-induced cardiomyocyte toxicityPrincipal Investigator
- Principal Investigator
  
  HOSODA HIROSHI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  National Cardiovascular Center Research Institute
The effect of intracardiac mechanical stress on fetal heart maturation in mammals
- Principal Investigator
  
  Miyoshi Takekazu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Center for Child Health and Development
Basical study on the Ghrelin's protective effect against the Radiation Injury.
- Principal Investigator
  
  Nishi Yoshihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kurume University
Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells.Principal Investigator
- Principal Investigator
  
  HOSODA HIROSHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  National Cardiovascular Center Research Institute
Epigenetic regulatory mechanisms of neural stem cell state in mouse pups with intrauterine growth retardation.
- Principal Investigator
  
  KATSURAGI Shinji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Cardiovascular Center Research Institute
Development of method for the systemic separation of fetal membrane-derived MSCs to establish the cell-specific transplantation therapy
- Principal Investigator
  
  IKEDA TOMOAKI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Cardiovascular Center Research Institute
The effect of ghrelin on hepatocyte proliferation and regenerative liver growth via the autonomic nervou s systemPrincipal Investigator
- Principal Investigator
  
  HOSODA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  National Cardiovascular Center Research Institute
エネルギー代謝状態の変化におけるグレリン生合成への影響(特に脂肪酸修飾について)Principal Investigator
- Principal Investigator
  
  細田洋司
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2017 2016 2015 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 肥満症(第2版)-基礎・臨床研究の進歩-2010
- Author(s)
  細田洋司、寒川賢治
- Total Pages
  776
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-21591190
[Book] 日本臨床、肥満症(第2版)2010
- Author(s)
  細田洋司・寒川賢治
- Total Pages
  776
- Data Source
  KAKENHI-PROJECT-21591190
[Book] 日本臨床者増刊高血圧(第4版)上巻2009
- Author(s)
  細田洋司・寒川賢治
- Total Pages
  704
- Data Source
  KAKENHI-PROJECT-21591190
[Book] 日本臨床社増刊高血圧(第4版)上巻2009
- Author(s)
  細田洋司, 他
- Total Pages
  704
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-21591190
[Book] 日本臨床社増刊肥満症(第2版)2009
- Author(s)
  細田洋司, 他
- Total Pages
  772
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-21591190
[Journal Article] Abnormal Microscopic Findings in the Placenta Correlate With the Severity of Fetal Heart Failure2023
- Author(s)
  Miyoshi Takekazu、Matsuyama Taka-aki、Nakai Michikazu、Miyazato Mikiya、Yoshimatsu Jun、Hatakeyama Kinta、Hosoda Hiroshi
- Journal Title
  
  Circ J
  
  Volume: 87 Issue: 4 Pages: 560-568
- DOI
  10.1253/circj.CJ-22-0568
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2023-03-24
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07833, KAKENHI-PROJECT-19K08343
[Journal Article] Plasma Clearance of Intravenously Infused Adrenomedullin in Rats with Acute Renal Failure2022
- Author(s)
  Hosoda Hiroshi、Nakamura Tsutomu、Yoshihara Fumiki
- Journal Title
  
  Biomolecules
  
  Volume: 12 Issue: 9 Pages: 1281-1281
- DOI
  10.3390/biom12091281
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07819, KAKENHI-PROJECT-20K07143
[Journal Article] Utility of perinatal natriuretic peptide for predicting neonatal heart failure2022
- Author(s)
  Miyoshi Takekazu、Hosoda Hiroshi、Miyake Akira、Sakaguchi Heima、Kitano Masataka、Kurosaki Ken‐ichi、Shiraishi Isao、Nakai Michikazu、Nishimura Kunihiro、Miyazato Mikiya、Kangawa Kenji、Yoshimatsu Jun、Minamino Naoto
- Journal Title
  
  Pediatrics International
  
  Volume: 64 Issue: 1
- DOI
  10.1111/ped.15231
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07833, KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-20K08414
[Journal Article] Significance of Atrial and Brain Natriuretic Peptide Measurements in Fetuses With Heart Failure2021
- Author(s)
  Miyoshi Takekazu、Hosoda Hiroshi、Minamino Naoto
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 12 Pages: 65435-65435
- DOI
  10.3389/fphys.2021.654356
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08414, KAKENHI-PROJECT-19K08343
[Journal Article] Combined evaluation of plasma B-type natriuretic peptide and urinary liver-type fatty acid-binding protein/creatinine ratio is related to worsening renal function in patients undergoing elective percutaneous coronary intervention2021
- Author(s)
  Yoshihara Fumiki、Hosoda Hiroshi、Doi Takahito、Yoshida Morikatsu、Kitamura Kazuo、Yamamoto Haruko、Asaumi Yasuhide、Ishibashi-Ueda Hatsue、Kishida Masatsugu、Arisato Tetsuya、Matsuo Miki、Miyazato Mikiya、Yasuda Satoshi
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 25 Issue: 12 Pages: 1319-1328
- DOI
  10.1007/s10157-021-02113-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09039, KAKENHI-PROJECT-20K07819, KAKENHI-PROJECT-21K08044
[Journal Article] Plasma natriuretic peptide levels reflect the status of the heart failure in fetuses with arrhythmia.2020
- Author(s)
  Miyoshi T, Hosoda H, Kurosaki K, Shiraishi I, Nakai M, Nishimura K, Miyazato M, Kangawa K, Ikeda T, Yoshimatsu J, Minamino N.
- Journal Title
  
  The Journal of Maternal-Fetal & Neonatal Medicine
  
  Volume: － Issue: 12 Pages: 1883-1889
- DOI
  10.1080/14767058.2019.1651271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-17K16316
[Journal Article] Induction of Immune Tolerance towards allogeneic cells using fetal directed placental injection in a Murine model.2020
- Author(s)
  Shimazu Y, Endo M, Miyoshi T, Takahashi K, Hosoda H, Tamai K, Flake AW, Kimura T, Yosimatsu J.
- Journal Title
  
  Journal of Stem Cell Research & Therapy
  
  Volume: 9 Pages: 456-456
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08343
[Journal Article] Maternal administration of tadalafil improves fetal ventricular systolic function in a Hey2 knockout mouse model of fetal heart failure.2020
- Author(s)
  Miyoshi T, Hisamitsu T, Ishibashi-Ueda H, Ikemura K, Ikeda T, Miyazato M, Kangawa K, Watanabe Y, Nakagawa O, Hosoda H.
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 302 Pages: 110-116
- DOI
  10.1016/j.ijcard.2019.12.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-17K08411, KAKENHI-PROJECT-17K16316, KAKENHI-PROJECT-18H02787, KAKENHI-PROJECT-19H03398
[Journal Article] Induction of Immune Tolerance towards allogeneic cells using fetal directed placental injection in a Murine model2020
- Author(s)
  Shimazu Y, Endo M, Miyoshi T, Takahashi K, Hosoda H, Tamai K, Flake AW, Kimura T, Yosimatsu J.
- Journal Title
  
  Journal of Stem Cell Research & Therapeutics
  
  Volume: 9 Pages: 456-456
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08343
[Journal Article] Maternal biomarkers for fetal heart failure in fetuses with congenital heart defects or arrhythmias2019
- Author(s)
  Miyoshi T, Hosoda H, Nakai M, Nishimura K, Miyazato M, Kangawa K, Ikeda T, Yoshimatsu J, Minamino N.
- Journal Title
  
  Am J Obstet Gynecol
  
  Volume: 220 Issue: 1 Pages: 104.e1-104.e15
- DOI
  10.1016/j.ajog.2018.09.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16316, KAKENHI-PROJECT-19K08343
[Journal Article] Tadalafil treatment in mice for preeclampsia with fetal growth restriction has neuro-benefic effects in offspring through modulating prenatal hypoxic conditions.2019
- Author(s)
  Tachibana Ryota, Umekawa Takashi, Yoshikawa Kento, Owa Takao, Magawa Shoichi, Furuhashi Fumi, Tsuji Makoto, Maki Shintaro, Shimada Kyoko, Kaneda K. Michiko, Nii Masafumi, Tanaka Hiroaki, Tanaka Kayo, Kamimoto Yuki, Kondo Eiji, Kato Ineko, Ikemura Kenji, Okuda Masahiro, et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 234-234
- DOI
  10.1038/s41598-018-36084-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08411, KAKENHI-PROJECT-17K08412, KAKENHI-PROJECT-17K09168, KAKENHI-PROJECT-17H04654, KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-19K09800, KAKENHI-PROJECT-19K17134, KAKENHI-PROJECT-17K16316
[Journal Article] Metabolism of atrial and brain natriuretic peptides in the fetoplacental circulation of fetuses with congenital heart diseases.2019
- Author(s)
  Miyoshi T, Hosoda H, Miyazato M, Kangawa K, Yoshimatsu J, Minamino N.
- Journal Title
  
  Placenta
  
  Volume: 83 Pages: 26-32
- DOI
  10.1016/j.placenta.2019.06.382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-17K16316
[Journal Article] Myeloprotective effects of C-type natriuretic peptide on cisplatin-induced bone marrow granulocytopenia in mice.2017
- Author(s)
  Zenitani M, Nojiri T, Kimura T, Hosoda H, Miura K, Hino J, Nakahata K, Uehara S, Miyazato M, Oue T, Okuyama H, Kangawa K
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 79 Issue: 2 Pages: 363-368
- DOI
  10.1007/s00280-016-3221-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-16K10700
[Journal Article] Atrial natriuretic peptide protects against bleomycin-induced pulmonary fibrosis via vascular endothelial cells in mice : ANP for pulmonary fibrosis.2017
- Author(s)
  Okamoto A, Nojiri T, Konishi K, Tokudome T, Miura K, Hosoda H, Hino J, Miyazato M, Kyomoto Y, Asai K, Hirata K, Kangawa K
- Journal Title
  
  Respir Res
  
  Volume: 18 Issue: 1 Pages: 1-1
- DOI
  10.1186/s12931-016-0492-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-15K09185, KAKENHI-PROJECT-16K10700
[Journal Article] Atrial natriuretic peptide protects against cisplatin-induced granulocytopenia.2016
- Author(s)
  Nojiri T, Hosoda H, Zenitani M, Tokudome T, Kimura T, Miura K, Miyazato M, Okumura M, Kangawa K
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 78 Issue: 1 Pages: 191-197
- DOI
  10.1007/s00280-016-3075-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-16K10700
[Journal Article] C-type natriuretic peptide in combination with sildenafil attenuates proliferation of rhabdomyosarcoma cells.2016
- Author(s)
  Zenitani M, Nojiri T, Uehara S, Miura K, Hosoda H, Kimura T, Nakahata K, Miyazato M, Okuyama H, Kangawa K.
- Journal Title
  
  Cancer Med.
  
  Volume: 5 Issue: 5 Pages: 795-805
- DOI
  10.1002/cam4.642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461393
[Journal Article] C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice.2016
- Author(s)
  Kimura T, Nojiri T, Hino J, Hosoda H, Miura K, Shintani Y, Inoue M, Zenitani M, Takabatake H, Miyazato M, Okumura M, Kangawa K.
- Journal Title
  
  Respiratory research
  
  Volume: 17 Issue: 1 Pages: 19-19
- DOI
  10.1186/s12931-016-0335-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-25461401, KAKENHI-PROJECT-26861135, KAKENHI-PROJECT-26293316
[Journal Article] Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells.2015
- Author(s)
  Nojiri T, Hosoda H, Tokudome T, Miura K, Ishikane S, Otani K, Kishimoto I, Shintani Y, Inoue M, Kimura T, Sawabata N, Minami M, Nakagiri T, Funaki S, Takeuchi Y, Maeda H, Kidoya H, Kiyonari H, Shioi G, Arai Y, Hasegawa T, Takakura N, Hori M, Ohno Y, Miyazato M, Mochizuki N, Okumura M, Kangawa K
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 112 Issue: 13 Pages: 4086-4091
- DOI
  10.1073/pnas.1417273112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112005, KAKENHI-PROJECT-24300330, KAKENHI-PUBLICLY-25122710, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-26861136, KAKENHI-PROJECT-26861319, KAKENHI-PROJECT-26461100, KAKENHI-PROJECT-15H04943, KAKENHI-PROJECT-25462176
[Journal Article] Exacerbation of bleomycin-induced injury by lipopolysaccharide in mice: establishment of a mouse model for acute exacerbation of interstitial lung diseases.2015
- Author(s)
  Kimura T, Nojiri T, Hosoda H, Shintani Y, Inoue M, Miyazato M, Okumura M, Kangawa K.
- Journal Title
  
  European journal of cardio-thoracic surgery
  
  Volume: 48 Issue: 4 Pages: e85-e91
- DOI
  10.1093/ejcts/ezv261
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-26861135, KAKENHI-PROJECT-26293316
[Journal Article] Protective effects of C-type natriuretic peptide on cisplatin-induced nephrotoxicity in mice2015
- Author(s)
  Kimura, T., Nojiri, T., Hosoda, H., Ishikane, S., Shintani, Y., Inoue, M., Miyazato, M., Okumura, M., Kangawa, K.
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 75(5) Issue: 5 Pages: 1057-1063
- DOI
  10.1007/s00280-015-2734-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861319, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-26861135, KAKENHI-PROJECT-26293316
[Journal Article] Moderate maternal food restriction in mice impairs physical growth, behaviors, and neurodevelopment of offspring2015
- Author(s)
  Akitake Y, Katsuragi S, Hosokawa M, Mishima K, Ikeda T, Miyazato M, Hosoda H
- Journal Title
  
  Neutrition Research
  
  Volume: 35 Issue: 1 Pages: 76-87
- DOI
  10.1016/j.nutres.2014.10.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591738, KAKENHI-PROJECT-24592495, KAKENHI-PROJECT-24791128
[Journal Article] Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo2012
- Author(s)
  Bando M, Nakao K, et al
- Journal Title
  
  Am. J. Physiol. Endocrinol. Metab.
  
  Volume: 302 Issue: 4 Pages: 403-408
- DOI
  10.1152/ajpendo.00341.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229013, KAKENHI-PROJECT-21390252, KAKENHI-PROJECT-21591190, KAKENHI-PLANNED-22126012, KAKENHI-PUBLICLY-23126510, KAKENHI-PROJECT-23791052, KAKENHI-PROJECT-23791055, KAKENHI-PROJECT-24659444
[Journal Article] Ghrelin levels are reduced in Rett syndrome patients with eating difficulties2011
- Author(s)
  Hara M, Hosoda H, et al
- Journal Title
  
  Int J Dev Neurosci
  
  Volume: 29 Issue: 8 Pages: 899-902
- DOI
  10.1016/j.ijdevneu.2011.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591190, KAKENHI-PROJECT-22591145
[Journal Article] PDK1-Foxo1 in Agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure2011
- Author(s)
  Cao Y, Nakata M, Okamoto S, Takano E, Yada T, Minokoshi Y, Hirata Y, Nakajima K, Iskandar K, Hayashi Y, Ogawa W, Barsh GS, Hosoda H, Kangawa K, Itoh H, Noda T, Kasuga M, Nakae J
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Issue: 4 Pages: 2100-2112
- DOI
  10.1371/journal.pone.0018324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390067, KAKENHI-PROJECT-21591190, KAKENHI-PLANNED-22126005, KAKENHI-PLANNED-22126011, KAKENHI-PROJECT-22240041, KAKENHI-PROJECT-22590995
[Journal Article] Centrally administered ghrelin activates cardiac vasal nerve in anesthetized rabbits2011
- Author(s)
  Shimizu S, Akiyama T, Kawada T, Sonobe T, Kamiya A, Shishido T, Tokudome T, Hosoda H, Shirai M, Kangawa K, Sugimachi M
- Journal Title
  
  Auton Neurosci
  
  Volume: 162 Issue: 1-2 Pages: 60-65
- DOI
  10.1016/j.autneu.2011.04.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J10987, KAKENHI-PROJECT-21591190, KAKENHI-PROJECT-22790891, KAKENHI-PROJECT-23592691, KAKENHI-PROJECT-23650213
[Journal Article] Dynamics of placental ghrelin production and its receptor expression in a Dahl salt-sensitive rat model of intrauterine growth restriction.2010
- Author(s)
  Nonoshita A, Hosoda H, et al.
- Journal Title
  
  Placenta
  
  Volume: 31 Pages: 358-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591190
[Journal Article] Generation of transgenic mice overexpressing a ghrelin analog2010
- Author(s)
  Yamada G, Ariyasu H, Iwakura H, Hosoda H, Akamizu T, Nakao K, Kangawa K
- Journal Title
  
  Endocrinology
  
  Volume: 151 Issue: 12 Pages: 5935-5940
- DOI
  10.1210/en.2010-0635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591190
[Journal Article] Generation of transgenic mice overexpressing a ghrelin analog.2010
- Author(s)
  Yamada G, Hosoda H, et al.
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 5935-5940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591190
[Journal Article] Reconstruction-dependent recovery from anorexia and time-related recovery of regulatory ghrelin system in gastrectomized rats.2010
- Author(s)
  Koizumi M, Hosoda H, et al.
- Journal Title
  
  International Journal of Peptides
  
  Volume: 2010 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591190
[Journal Article] Regional distribution on the dynamics of n-decanoyl ghrelin, another acylform of ghrelin, upon fasting in rogents.2009
- Author(s)
  Hiejima H, Hosoda H, et al.
- Journal Title
  
  Regulatory Peptides 156
  
  Pages: 47-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591190
[Journal Article] Regional distribution and the dynamics of n-decanoyl ghrelin, another acyl-form of ghrelin, upon fasting in rodents2009
- Author(s)
  Hiejima H, Nishi Y, Hosoda H, Yoh J, Mifune H, Satou M, Sugimoto H, Chiba S, Kawahara Y, Tanaka E, Yoshimatsu H, Uchimura N, Kangawa K, Kojima M
- Journal Title
  
  Regul Pept
  
  Volume: 156 Issue: 1-3 Pages: 47-56
- DOI
  10.1016/j.regpep.2009.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591190
[Presentation] 胎児胎盤循環におけるナトリウム利尿ペプチドの代謝2021
- Author(s)
  三好剛一、細田洋司、吉松　淳、南野直人
- Organizer
  第27回日本胎児心臓病学会
- Data Source
  KAKENHI-PROJECT-19K08343
[Presentation] 胎児胎盤循環におけるナトリウム利尿ペプチドの分子型及び代謝2021
- Author(s)
  三好剛一、細田洋司、吉松　淳、南野直人
- Organizer
  第57回日本周産期・新生児医学会
- Data Source
  KAKENHI-PROJECT-19K08343
[Presentation] 血中および尿中バイオマーカーによる冠動脈形成術後の腎機能障害の予測性に関する2021
- Author(s)
  吉原史樹、細田洋司、岸田真嗣、有里哲哉、松尾実紀、小島詩織
- Organizer
  第64回日本腎臓学会
- Data Source
  KAKENHI-PROJECT-20K07819
[Presentation] Metabolism of atrial and brain natriuretic peptides in the fetoplacental circulation of fetuses with congenital heart diseases2021
- Author(s)
  Miyoshi T, Hosoda H, Yoshimatsu J, Minamino N
- Organizer
  第73回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-19K08343
[Presentation] シンポジウム8「CKD・DKD診療の新展開」　 CKD領域の新規薬物治療2021
- Author(s)
  吉原史樹、岸田真嗣、有里哲哉、松尾実紀、細田洋司
- Organizer
  第51回日本腎臓学会・東部
- Invited
- Data Source
  KAKENHI-PROJECT-20K07819
[Presentation] An Elevated Urinary Liver-Type Fatty Acid-Binding Protein/Creatinine Ratio One Day after Percutaneous Coronary Intervention is Relat ed to Worsening Renal Function2020
- Author(s)
  Fumiki Yoshihara, Hiroshi Hosoda, Toshimitsu Hamasaki, Kazuo Kitamura, Haruko Yamamoto, Yasuhide Asaumi, Hatsue Ishibashi-Ueda, Masatsugu Kishida, Tetsuya Arisato, Satoshi Yasuda
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-20K07819
[Presentation] 胎児心不全における母体血中バイオマーカー2019
- Author(s)
  三好剛一、細田洋司、吉松　淳、池田智明、南野直人.
- Organizer
  日本周産期・新生児医学会
- Data Source
  KAKENHI-PROJECT-19K08343
[Presentation] 母体血清を用いた胎児心不全診断法の開発2019
- Author(s)
  三好剛一、細田洋司、吉松　淳、池田智明、南野直人.
- Organizer
  日本胎児治療学会
- Data Source
  KAKENHI-PROJECT-19K08343
[Presentation] 胎児心不全診断におけるナトリウム利尿ペプチド測定の意義2019
- Author(s)
  細田洋司、三好剛一、吉松　淳、池田智明、南野直人.
- Organizer
  日本心血管内分泌代謝学会
- Data Source
  KAKENHI-PROJECT-19K08343
[Presentation] 放射線被ばく後のグレリン産生・分泌動態とグレリンによる血球保護効果の検討2016
- Author(s)
  西芳寛、那須沙織、細田洋司、御船弘治、児島将康ほか
- Organizer
  第89回日本内分泌学会各術総会
- Place of Presentation
  京都
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16K09814
[Presentation] ANPの血管内皮細胞の接着分子制御による癌細胞の転移抑制効果について2015
- Author(s)
  細田洋司、野尻崇、石兼真、三浦浩一、宮里幹也、寒川賢治
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26461393
[Presentation] グレリンはラット肝切除後の肝再生を促進する2009
- Author(s)
  細田洋司
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  群馬県民会館
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21591190
[Presentation] グレリンはラット肝切除後の肝再生を促進する2009
- Author(s)
  細田洋司, 他
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  群馬県民会館(群馬県)
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21591190
[Presentation] ANPの血管内皮細胞の接着分子制御による癌細胞の転移抑制効果について
- Author(s)
  細田洋司、野尻崇、石兼真、三浦浩一、宮里幹也、寒川賢治
- Organizer
  第88回日本内科学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-04-23 – 2015-04-25
- Data Source
  KAKENHI-PROJECT-26461393

1. Yoshihara Fumiki (70393220)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. KANGAWA Kenji (00112417)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. Kanda Yasunari (70510387)

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6. MIYAZATO Mikiya (50291183)

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9. OTANI Kentaro (50470191)

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10. INUBUSHI Masayuki (70399830)

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11. KATSURAGI Shinji (50521283)

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12. AKITAKE Yoshiharu (20508791)

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13. Nishi Yoshihiro (20352122)

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14. Miyoshi Takekazu (70626697)

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# of Collaborated Products: 13 results
15. Makino Hisashi (80399609)

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17. 大嶌麻妃子 (50637527)

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20. JUNG Kyongsook (00598097)

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25. 孫徹 (60572287)

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26. 福嶌教偉 (30263247)

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27. 芦原貴司 (80396259)

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33. 武田麻衣子 (40398441)

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35. 座間味義人 (70550250)

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36. 河嶋秀和 (70359438)

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37. 福田哲也 (90443506)

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38. 立石恵実 (20795596)

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39. 飯田秀博 (30322720)

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40. 太田靖利 (90388570)

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41. NASU saori

# of Collaborated Projects: 1 results

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42. KOJIMA masayasu

# of Collaborated Projects: 1 results

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43. IKEMURA Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. HOSOKAWA Masato

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45. 南野直人

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47. 岡本士毅

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48. 箕越靖彦

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49. 高倉伸幸

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50. 奥田真弘

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51. 中尾一和

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52. 吉田守克

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# of Collaborated Products: 1 results

HOSODA HIROSHI 細田 洋司

HOSODA Hiroshi 細田 洋司

細田 洋司 ホソダ ヒロシ

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骨格筋の新機能としての老廃物除去機能を解明するPrincipal Investigator

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The role of DNA methylation in anticancer drug-induced cardiomyocyte toxicityPrincipal Investigator

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Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells.Principal Investigator

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The effect of ghrelin on hepatocyte proliferation and regenerative liver growth via the autonomic nervou s systemPrincipal Investigator

HOSODA HIROSHI 細田洋司

HOSODA Hiroshi 細田洋司

細田洋司ホソダヒロシ

[Book] 日本臨床社増刊高血圧(第4版)上巻2009

[Book] 日本臨床社増刊肥満症(第2版)2009