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Shimada Muneaki  島田 宗昭

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SHIMADA Muneaki  島田 宗昭

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Researcher Number 40362892
Other IDs
Affiliation (Current) 2026: 東北大学, 未来型医療創成センター, 教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 東北大学, 未来型医療創成センター, 教授
2018 – 2021: 東北大学, 医学系研究科, 准教授
2017: 東北大学, 大学病院, 准教授
2014 – 2015: 鳥取大学, 医学部, 講師
2012 – 2013: 鳥取大学, 医学部, 助教
2007: Maori University, Faculty of Medicine, Assistant Professor
2006: 鳥取大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Except Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
メタボローム解析 / 難治性がん / 鑑別診断 / 難治性 / 化学療法抵抗性 / 粘液性癌 / 卵巣癌 / 難治性癌 / プロテオーム解析 / オミックス解析 … More / 多層的オミックス解析 / 婦人科難治性希少がん / 卵巣粘液性癌 / 放射線感受性 / 化学療法感受性 / 非扁平上皮癌 / 個別化医療 / 集学的治療 / 化学療法 / 組織亜型 / 子宮頸癌 … More
Except Principal Investigator
卵巣癌 / メタボローム / セラミド / 薬剤耐性 / 白金製剤 / 明細胞癌 / 前向きコホート研究 / リスク低減卵管卵巣摘出術 / BRCA1,BRCA2 / 遺伝性腫瘍 / 臨床研究 / 遺伝性乳癌卵巣癌症候群 / マルチオミックス / プロテオーム / 全ゲノム解析 / 全エクソーム解析 / スフィンゴ脂質 / メタボローム解析 / 卵巣明細胞癌 / 白金抵抗性 / 卵巣がん / クロマチンリモデリング / 循環腫瘍DNA / がんゲノム解析 / 婦人科がん / メタボロミクス / オミックス / バイオマーカー / プラチナ耐性 / オルガノイドモデル / プラチナ感受性 / オルガノイド / CHD4 / 治療抵抗性 / Chemoresponse / Gene therapy / Carcinoma / 薬剤反応性 / 遺伝子 / 癌 / mTOR阻害剤 / PI3K阻害剤 / PIK3CA / PI3K / 明細胞腺癌 / FGFR2 / 卵巣明細胞腺癌 Less
  • Research Projects

    (10 results)
  • Research Products

    (52 results)
  • Co-Researchers

    (28 People)
  •  Multicenter study to stratify ovarian cancer risk factors in women with BRCA pathogenic variants carriers.

    • Principal Investigator
      平沢 晃
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Okayama University
  •  A multi-omics investigation of novel therapeutic strategies for clear cell carcinoma of the ovary focusing on cancer metabolism

    • Principal Investigator
      重田 昌吾
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tohoku University
  •  Development of a New Treatment Strategy for Refractory Ovarian Mucinous CarcinomaPrincipal Investigator

    • Principal Investigator
      SHIMADA Muneaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tohoku University
  •  Elucidation of the mechanism of drug resistance in ovarian cancer with poor prognosis and development of new therapeutic targets

    • Principal Investigator
      TOKUNAGA Hideki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tohoku University
  •  An investigation of novel therapeutic strategies for platinum-resistant ovarian cancer using cancer organoid originated from disseminating ovarian carcinoma

    • Principal Investigator
      TSUJI Keita
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tohoku University
  •  Comprehensive genomic and transcriptome analyses to clarify molecular mechanisms contributing to chemoresistance in gynecologic cancer

    • Principal Investigator
      YAEGASHI Nobuo
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tohoku University
  •  An attempt to establish a new treatment for non-squamous cell carcinoma of the uterine cervixPrincipal Investigator

    • Principal Investigator
      SHIMADA Muneaki
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Development of combination therapy using PI3K inhibitor and its predictive biomarker in clear cell carcinoma of the ovary

    • Principal Investigator
      Oishi Tetsuro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tottori University
  •  Fibroblast growth factor receptor 2 is associated with poor overall survival in clear cell carcinoma of the ovary and may be a novel therapeutic approach

    • Principal Investigator
      ITAMOCHI Hiroaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tottori University
  •  Adenovirus type 5 EIA gene therapy for ovarian carcinoma

    • Principal Investigator
      ITAMOCHI Hiroaki
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tottori University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2005

All Journal Article Presentation

  • [Journal Article] Nationwide survey of the secondary findings in cancer genomic profiling: survey including liquid biopsy2024

    • Author(s)
      Shimada Saki、Yamada Takahiro、Minamoto Akari、Matsukawa Manami、Yabe Ichiro、Tada Hiroshi、Oda Katsutoshi、Ueki Arisa、Higashigawa Satomi、Morikawa Maki、Sato Yuki、Hirasawa Akira、Ogawa Masanobu、Kondo Tomohiro、Yoshioka Masahiro、Kanai Masashi、Muto Manabu、Kosugi Shinji
    • Journal Title

      Journal of Human Genetics

      Volume: 70 Issue: 1 Pages: 33-40

    • DOI

      10.1038/s10038-024-01294-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07469, KAKENHI-PROJECT-24K02584, KAKENHI-PROJECT-24K02589
  • [Journal Article] Uptake and Outcomes of Neoadjuvant Chemotherapy Among US Patients With Less Common Epithelial Ovarian Carcinomas2023

    • Author(s)
      Matsuo Koji、Matsuzaki Shinya、Maeda Michihide、Rau Alesandra R.、Yoshihara Kosuke、Tamura Ryo、Shimada Muneaki、Machida Hiroko、Mikami Mikio、Klar Maximilian、Roman Lynda D.、Wright Jason D.、Sood Anil K.、Gershenson David M.
    • Journal Title

      JAMA Network Open

      Volume: 6 Issue: 6 Pages: 2318602-2318602

    • DOI

      10.1001/jamanetworkopen.2023.18602

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09635, KAKENHI-PROJECT-23K08854, KAKENHI-PROJECT-21K09486, KAKENHI-PROJECT-20H03828
  • [Journal Article] Identification of predictive biomarkers for diagnosis and radiation sensitivity of uterine cervical cancer using wide‐targeted metabolomics2023

    • Author(s)
      Hishinuma Eiji、Shimada Muneaki、Matsukawa Naomi、Li Bin、Motoike Ikuko N.、Hagihara Tatsuya、Shigeta Shogo、Tokunaga Hideki、Saigusa Daisuke、Kinoshita Kengo、Koshiba Seizo、Yaegashi Nobuo
    • Journal Title

      Journal of Obstetrics and Gynaecology Research

      Volume: 49 Issue: 8 Pages: 2109-2117

    • DOI

      10.1111/jog.15709

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09486, KAKENHI-PROJECT-21K09531, KAKENHI-PROJECT-23K24478, KAKENHI-PROJECT-23K27316
  • [Journal Article] Homologous Recombination Inquiry Through Ovarian Malignancy Investigations: JGOG3025 study.2023

    • Author(s)
      Yoshihara K, Baba T, Tokunaga H, Nishino K, Sekine M, Takamatsu S, Matsumura N, Yoshida H, Kajiyama H, Shimada M, Kagimura T, Oda K, Sasajima Y, Yaegashi N, Okamoto A, Sugiyama T, Enomoto T
    • Journal Title

      Cancer Sci

      Volume: Online ahead of print Issue: 6 Pages: 2515-2523

    • DOI

      10.1111/cas.15747

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09548, KAKENHI-PROJECT-21K09531, KAKENHI-PROJECT-21H03074, KAKENHI-PROJECT-23K27741
  • [Journal Article] Identification of predictive biomarkers for endometrial cancer diagnosis and treatment response monitoring using plasma metabolome profiling2023

    • Author(s)
      Hishinuma Eiji、Shimada Muneaki、Matsukawa Naomi、Shima Yoshiko、Li Bin、Motoike Ikuko N.、Shibuya Yusuke、Hagihara Tatsuya、Shigeta Shogo、Tokunaga Hideki、Saigusa Daisuke、Kinoshita Kengo、Koshiba Seizo、Yaegashi Nobuo
    • Journal Title

      Cancer & Metabolism

      Volume: 11 Issue: 1

    • DOI

      10.1186/s40170-023-00317-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09486, KAKENHI-PROJECT-21K09531, KAKENHI-PROJECT-23K24478, KAKENHI-PROJECT-23K27316
  • [Journal Article] An Attempt to Develop a New Treatment Strategy for Rare Refractory Gynecological Malignancies: The Japanese Gynecologic Oncology Group2023

    • Author(s)
      Shigeta S, Shimada M, Suzuki S, Kajiyama H, Oda K, Takehara K, Mandai M, Aoki D, Enomoto T, Okamoto A.
    • Journal Title

      JMA Journal

      Volume: 6 Issue: 4 Pages: 527-531

    • DOI

      10.31662/jmaj.2023-0024

    • ISSN
      2433-328X, 2433-3298
    • Year and Date
      2023-10-16
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09486, KAKENHI-PROJECT-21H03074, KAKENHI-PROJECT-23K21473
  • [Journal Article] Comparison of treatment outcomes between first-line chemotherapy with or without bevacizumab for advanced ovarian, fallopian tube, and primary peritoneal cancer (Tohoku gynecologic cancer unit: TGCU-RS001 study)2022

    • Author(s)
      Takatori E, Nagasawa T, Kagabu M, Baba T, Shigeto T, Matsumura Y, Shimizu D, Terada Y, Seino M, Ohta T, Nagase S, Shigeta S, Tokunaga H, Shimada M, Kaiho-Sakuma M, Furukawa S, Soeda S, Watanabe T, Takahashi F, Yokoyama Y.
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 27 Issue: 12 Pages: 1874-1880

    • DOI

      10.1007/s10147-022-02246-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09531, KAKENHI-PROJECT-21K09548
  • [Journal Article] A Retrospective Analysis of Clinical Biomarkers for Olaparib Maintenance Therapy in Patients with Recurrent Ovarian Cancer2022

    • Author(s)
      Endo Shun、Shigeta Shogo、Tokunaga Hideki、Shimizu Takanori、Hasegawa-Minato Junko、Hashimoto Chiaki、Ishibashi Masumi、Nagai Tomoyuki、Shiga Naomi、Shimada Muneaki、Yaegashi Nobuo
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 258 Issue: 1 Pages: 1-9

    • DOI

      10.1620/tjem.2022.J050

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09531
  • [Journal Article] Rethinking the significance of surgery for uterine cervical cancer.2022

    • Author(s)
      Shimada M, Tsuji K, Shigeta S, Nagai T, Watanabe Z, Tokunaga H, Kigawa J, Yaegashi N.
    • Journal Title

      J Obstet Gynaecol Res.

      Volume: 48(3) Issue: 3 Pages: 576-586

    • DOI

      10.1111/jog.15112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03795
  • [Journal Article] MicroRNA-152 Regulates Endometrial Serous Carcinoma Cell Motility by Suppressing Matrix Metalloproteinase 10 Expression2022

    • Author(s)
      Shigeta S, Watanabe Y, Suzuki F, Nagase S, Shibuya Y, Ishibashi M, Nagai T, Shiga N, Toyoshima M, Tokunaga H, Shimada M, Yaegashi N.
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 256 Issue: 3 Pages: 249-258

    • DOI

      10.1620/tjem.256.249

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03795
  • [Journal Article] Risk assessment in the patients with uterine cervical cancer harboring intermediate risk factors after radical hysterectomy: a multicenter, retrospective analysis by the Japanese Gynecologic Oncology Group2022

    • Author(s)
      Shigeta Shogo、Shimada Muneaki、Tsuji Keita、Nagai Tomoyuki、Tanase Yasuhito、Matsuo Koji、Kamiura Shoji、Iwata Takashi、Yokota Harushige、Mikami Mikio
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 27 Issue: 9 Pages: 1507-1515

    • DOI

      10.1007/s10147-022-02198-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-22H04923
  • [Journal Article] Prognostic factors of 2018 FIGO stage IB-IIA cervical cancer with absence of high/ intermediate surgical-pathological risk factors2022

    • Author(s)
      Shibuya Yusuke、Shimada Muneaki、Tsuji Keita、Shigeta Shogo、Tanase Yasuhito、Matsuo Koji、Yamaguchi Satoshi、Kanao Hiroyuki、Saito Toshiaki、Mikami Mikio
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 52 Pages: 1289-1296

    • DOI

      10.1093/jjco/hyac125

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-22H04923
  • [Journal Article] Liquid biopsy with droplet digital PCR targeted to specific mutations in plasma cell-free tumor DNA can detect ovarian cancer recurrence earlier than CA125.2021

    • Author(s)
      Minato T, Ito S, Li B, Fujimori H, Mochizuki M, Yamaguchi K, Tamai K, Shimada M, Tokunaga H, Shigeta S, Sato I, Shima H, Yamada H, Yaegashi N, Yasuda J.
    • Journal Title

      Gynecol Oncol Rep.

      Volume: 38 Pages: 100847-100847

    • DOI

      10.1016/j.gore.2021.100847

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-21K07137, KAKENHI-PROJECT-21K09482
  • [Journal Article] Clinico-pathological characteristics of patients with stage IB1-IB2 (FIGO 2018) uterine cervical cancer: a nationwide study in Japan.2021

    • Author(s)
      Tsuji K, Shimada M, Takahashi F, Tokunaga H, Deura I, Yamaguchi S, Nakanishi T, Matsuo K, Yaegashi N, Mikami M.
    • Journal Title

      Int J Clin Oncol.

      Volume: 26(8) Issue: 8 Pages: 1541-1552

    • DOI

      10.1007/s10147-021-01938-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-20H03828, KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-16H06277
  • [Journal Article] Prospective evaluation of sentinel node navigation surgery in Japanese patients with low-risk endometrial cancer-safety and occurrence of lymphedema.2021

    • Author(s)
      Niikura H, Toki A, Nagai T, Okamoto S, Shigeta S, Tokunaga H, Shimada M, Watanabe M, Yaegashi N.
    • Journal Title

      Jpn J Clin Oncol

      Volume: 51(4) Issue: 4 Pages: 584-589

    • DOI

      10.1093/jjco/hyaa252

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03795
  • [Journal Article] Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes from a dataset of 3,552 Japanese whole genomes (3.5KJPNv2)2021

    • Author(s)
      Tokunaga Hideki、Iida Keita、Hozawa Atsushi、Ogishima Soichi、Watanabe Yoh、Shigeta Shogo、Shimada Muneaki、Yamaguchi-Kabata Yumi、Tadaka Shu、Katsuoka Fumiki、Ito Shin、Kumada Kazuki、Hamanaka Yohei、Fuse Nobuo、Kinoshita Kengo、Yamamoto Masayuki、Yaegashi Nobuo、Yasuda Jun
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 1 Pages: e0236907-e0236907

    • DOI

      10.1371/journal.pone.0236907

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11545, KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K07193, KAKENHI-PROJECT-21K07111
  • [Journal Article] Establishment of a Diagnostic Method for Pelvic Sentinel Lymph Node Metastasis by Contrast-Enhanced Ultrasound in Uterine Cancer.2021

    • Author(s)
      Toki A, Niikura H, Mori N, Shigeta S, Nagai T, Tokunaga H, Shimada M, Yaegashi N.
    • Journal Title

      Ultrasound Med Biol.

      Volume: 47(8) Issue: 8 Pages: 2107-2116

    • DOI

      10.1016/j.ultrasmedbio.2021.03.040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03795
  • [Journal Article] A Single Arm Prospective Pilot Study Examining the Efficacy and Safety of Bevacizumab Single Maintenance Therapy Following Platinum-Based Chemotherapy in Patients with Advanced or Recurrent Cervical Cancer.2021

    • Author(s)
      Toyoshima M, Shimada M, Sasaki S, Ishibashi M, Shigeta S, Tsuji K, Nagai T, Tokunaga H, Niikura H, Yaegashi N.
    • Journal Title

      Tohoku J Exp Med.

      Volume: 254(3) Issue: 3 Pages: 145-153

    • DOI

      10.1620/tjem.254.145

    • NAID

      130008061848

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K11265
  • [Journal Article] CHD4 regulates platinum sensitivity through MDR1 expression in ovarian cancer: A potential role of CHD4 inhibition as a combination therapy with platinum agents.2021

    • Author(s)
      Oyama Y, Shigeta S, Tokunaga H, Tsuji K, Ishibashi M, Shibuya Y, Shimada M, Yasuda J, Yaegashi N.
    • Journal Title

      PLoS One.

      Volume: 16(6) Issue: 6 Pages: 0251079-0251079

    • DOI

      10.1371/journal.pone.0251079

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-19K09747, KAKENHI-PROJECT-21K09531, KAKENHI-PROJECT-20K18211
  • [Journal Article] Docetaxel and carboplatin chemotherapy for treating patients with stage IVB or recurrent non-squamous cell carcinoma of the uterine.2021

    • Author(s)
      Shimada M, Sato S, Shoji T, Nagao S, Tokunaga H, Sueoka K, Takehara K, Nakamura K, Yamaguchi S, Kigawa J.
    • Journal Title

      Int J Clin Oncol

      Volume: 26 Issue: 7 Pages: 1314-1321

    • DOI

      10.1007/s10147-021-01903-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11265
  • [Journal Article] The Impact of Histological Subtype on Survival Outcome of Patients with Stage IIB-IVA Cervical Cancer Who Received Definitive Radiotherapy2021

    • Author(s)
      Miyahara S, Tsuji K, Shimada M, Shibuya Y, Shigeta S, Nagai T, Umezawa R, Tokunaga H, Jingu K, Yaegashi N.
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 255 Issue: 4 Pages: 303-313

    • DOI

      10.1620/tjem.255.303

    • NAID

      130008129404

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K11265
  • [Journal Article] Wide-Targeted Metabolome Analysis Identifies Potential Biomarkers for Prognosis Prediction of Epithelial Ovarian Cancer2021

    • Author(s)
      Hishinuma E, Shimada M, Matsukawa N, Saigusa D, Li B, Kudo K, Tsuji K, Shigeta S, Tokunaga H, Kumada K, Komine K, Shirota H, Aoki Y, Motoike IN, Yasuda J, Kinoshita K, Yamamoto M, Koshiba S, Yaegashi N.
    • Journal Title

      Toxins (Basel).

      Volume: 13 Issue: 7 Pages: 461-461

    • DOI

      10.3390/toxins13070461

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07657, KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-21K09486, KAKENHI-PROJECT-21K09531
  • [Journal Article] Impact of Histopathological Risk Factors on the Treatment of Stage IB-IIB Uterine Cervical Cancer2020

    • Author(s)
      Shimada Muneaki、Tokunaga Hideki、Kigawa Junzo、Yaegashi Nobuo
    • Journal Title

      The Tohoku Journal of Experimental Medicine

      Volume: 252 Issue: 4 Pages: 339-351

    • DOI

      10.1620/tjem.252.339

    • NAID

      130007953560

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11265
  • [Journal Article] Management of Stage IIB Cervical Cancer: an Overview of the Current Evidence.2020

    • Author(s)
      Matsuzaki S, Klar M, Mikami M, Shimada M, Grubbs BH, Fujiwara K, Roman LD, Matsuo K
    • Journal Title

      Curr Oncol Rep

      Volume: 22(3) Issue: 3 Pages: 28-28

    • DOI

      10.1007/s11912-020-0888-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04340, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-20H03828
  • [Journal Article] Perioperative treatments for stage IB-IIB uterine cervical cancer2020

    • Author(s)
      Shimada Muneaki、Tokunaga Hideki、Kobayashi Hiroaki、Ishikawa Mitsuya、Yaegashi Nobuo
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 50 Issue: 2 Pages: 99-103

    • DOI

      10.1093/jjco/hyz200

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11265
  • [Journal Article] Significance of Malignant Peritoneal Cytology on the Survival of Women with Early-Stage Cervical Cancer: A Japanese Gynecologic Oncology Group Study2019

    • Author(s)
      Matsuo Koji、Shimada Muneaki、Matsuzaki Shinya、Machida Hiroko、Nagase Yoshikazu、Saito Toshiaki、Kamiura Shoji、Iwata Takashi、Sugiyama Toru、Mikami Mikio
    • Journal Title

      Journal of Clinical Medicine

      Volume: 8 Issue: 11 Pages: 1822-1822

    • DOI

      10.3390/jcm8111822

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-17H04340, KAKENHI-PROJECT-16H06277
  • [Journal Article] Neoadjuvant chemotherapy with taxane and platinum followed by radical hysterectomy for stage IB2-IIB cervical cancer: Impact of histology type on survival.2019

    • Author(s)
      Matsuo K, Shimada M, Yamaguchi S, Kigawa J, Tokunaga H, Tabata T, Kodama J, Kawana K, Mikami M, Sugiyama T.
    • Journal Title

      Journal of Clinical Medicine

      Volume: 30: 8(2) Issue: 2 Pages: 156-169

    • DOI

      10.3390/jcm8020156

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-18K09303, KAKENHI-PROJECT-17H04340
  • [Journal Article] Association of Radical Hysterectomy Surgical Volume and Survival for Early-Stage Cervical Cancer2019

    • Author(s)
      Matsuo Koji、Shimada Muneaki、Yamaguchi Satoshi、Matoda Maki、Nakanishi Toru、Kikkawa Fumitaka、Ohmichi Masahide、Okamoto Aikou、Sugiyama Toru、Mikami Mikio
    • Journal Title

      Obstetrics & Gynecology

      Volume: 133 Issue: 6 Pages: 1086-1098

    • DOI

      10.1097/aog.0000000000003280

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-17H04340, KAKENHI-PROJECT-16H06277
  • [Journal Article] Predictors for pathological parametrial invasion in clinical stage IIB cervical cancer.2019

    • Author(s)
      Matsuo K, Shimada M, Nakamura K, Takei Y, Ushijima K, Sumi T, Ohara T, Yahata H, Mikami M, Sugiyama T.
    • Journal Title

      Eur J Sur Oncol

      Volume: - Issue: 8 Pages: 1417-1424

    • DOI

      10.1016/j.ejso.2019.02.019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-17H04340, KAKENHI-PROJECT-16H06277
  • [Journal Article] Chemoresistance of gastric-type mucinous carcinoma of the uterine cervix: a study of the Sankai Gynecology Study Group.2018

    • Author(s)
      Kojima A, Shimada M, Mikami Y, Nagao S, Takeshima N, Sugiyama T, Teramoto N, Kiyokawa T, Kigawa J, Nishimura R, Sankai Gynecology Study Group (SGSG)
    • Journal Title

      Int J Gynecol Cancer

      Volume: 28(1) Issue: 1 Pages: 99-106

    • DOI

      10.1097/igc.0000000000001145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11265
  • [Journal Article] Risk stratification models for peri-aortic lymph node metastasis and recurrence in stage IB-IIB cervical cancer.2018

    • Author(s)
      Matsuo K, Shimada M, Tsuyoshi Saito T, Takehara K, Tokunaga H, Watanabe Y, Todo Y, Morishige K, Mikami M, Sugiyama T.
    • Journal Title

      J Gynecol Oncol.

      Volume: 29 (1):e11. Issue: 1

    • DOI

      10.3802/jgo.2018.29.e11

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-18K09257, KAKENHI-PROJECT-17H04340
  • [Journal Article] Effectiveness of adjuvant systemic chemotherapy for intermediate-risk stage IB cervical cancer2017

    • Author(s)
      Matsuo Koji、Shimada Muneaki、Yokota Harushige、Satoh Toyomi、Katabuchi Hidetaka、Kodama Shoji、Sasaki Hiroshi、Matsumura Noriomi、Mikami Mikio、Sugiyama Toru
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 63 Pages: 106866-106875

    • DOI

      10.18632/oncotarget.22437

    • NAID

      120007134533

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-17H04340, KAKENHI-PROJECT-16K15707
  • [Journal Article] Comparison of adjuvant therapy for node-positive clinical stage IB-IIB cervical cancer: Systemic chemotherapy versus pelvic irradiation.2017

    • Author(s)
      Matsuo K, Shimada M, Aoki Y, Sakamoto M, Takeshima N, Fujiwara H, Matsumoto T, Mikami M, Sugiyama T.
    • Journal Title

      Int J Cancer

      Volume: 141 (5) Issue: 5 Pages: 1042-1051

    • DOI

      10.1002/ijc.30793

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11265, KAKENHI-PROJECT-17H04340
  • [Journal Article] The PI3K/mTOR dual Inhibitor NVP-BEZ235 Reduces Growth of Ovarian Clear Cell Carcinoma.2014

    • Author(s)
      Oishi T, Itamochi H, Kudoh A, Nonaka M, Kato M, Nishimura M, Oumi N, Sato S, Naniwa J, Sato S, Shimada M, Kigawa J, Harada T.
    • Journal Title

      Oncology Report

      Volume: 32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462594
  • [Journal Article] Checkpoint kinase inhibitor AZD7762 overcomes cisplatin resistance in clear cell carcinoma of the ovary.2014

    • Author(s)
      Itamochi H, Nishimura M, Oumi N, Kato M, Oishi T, Shimada M, Sato S, Naniwa J, Sato S, Kudoh A, Kigawa J, Harada H.
    • Journal Title

      Int J Gynecol Cancer

      Volume: 24 Issue: 1 Pages: 61-69

    • DOI

      10.1097/igc.0000000000000014

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592517
  • [Journal Article] Dual inhibition of phosphatidylinositol 3’-kinase and mammalian target of rapamycin using NVP-BEZ235 as a vovel therapeutic approach for mucinous adenocarcinoma of the ovary.2014

    • Author(s)
      Kudoh A, Oishi T, Itamochi H, Sato S, Naniwa J, Sato S, Shimada M, Kigawa J, Harada T.
    • Journal Title

      Int J Gynecol Cancer

      Volume: 24 Issue: 3 Pages: 444-453

    • DOI

      10.1097/igc.0000000000000091

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592517
  • [Journal Article] Establishment and characterization of a novel ovarian clear cell adenocarcinoma cell line, TU-OC-1, with a mutation in the PIK3CA gene.2013

    • Author(s)
      Itamochi H., Kato M., Nishimura M., Oumi N., Oishi T., Shimada M., Sato S., Naniwa J., Sato S., Nonaka M., Kudoh A., Terakawa N., Kigawa J., and Harada T.
    • Journal Title

      Human Cell

      Volume: 26 Issue: 3 Pages: 121-127

    • DOI

      10.1007/s13577-013-0062-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592517
  • [Journal Article] Outcome of patients with early ovarian cancer undergoing three courses of adjuvant chemotherapy following complete surgical staging2005

    • Author(s)
      Muneaki, Shimada
    • Journal Title

      International Journal of Gynecological Cancer 15

      Pages: 601-605

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591737
  • [Journal Article] Outcome of patients with early ovarian cancer undergoing three courses of adjuvant chemotherapy following complete surgical staging.2005

    • Author(s)
      Muneaki Shimada
    • Journal Title

      International Journal of Gynecological Cancer 15

      Pages: 601-605

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591737
  • [Presentation] 血中代謝産物に着目した経時的リキッドバイオプシーによる進行再発卵巣癌モニタリング法の開発2024

    • Author(s)
      重田昌吾 菱沼英史、島田宗昭、渋谷祐介、湊敬道、安田純、清水孝規、宮原周子、湊純子、橋本千明、石橋ますみ、徳永英樹、八重樫伸生
    • Organizer
      第66回日本婦人科腫瘍学会
    • Data Source
      KAKENHI-PROJECT-23K06688
  • [Presentation] Sequential Plasma Metabolome Analysis for Monitoring Therapeutic Response in Ovarian Cancer2024

    • Author(s)
      Shogo Shigeta, Eiji Hishinuma, Naomi Natsukawa, Yusuke Shibuya, Muneaki Shimada
    • Organizer
      Asian Society of Gynecologic Oncology 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06688
  • [Presentation] How to treat Non-high grade serous carcinoma - Low-grade serous carcinoma, Clear cell carcinoma, Mucinous carcinoma-2023

    • Author(s)
      Muneaki Shimada
    • Organizer
      International Gynecologic Cancer Society 2023, Master Session, Seoul
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09486
  • [Presentation] 子宮体癌における血漿メタボローム解析による新規バイオマーカーの探索2023

    • Author(s)
      萩原達也,島田宗昭, 菱沼英史, 李 賓, 橋本栄文, 栃木実佳子, 遠藤 俊, 清水孝規, 湊 純子, 渋谷祐介, 橋本千明, 石橋ますみ, 重田昌吾, 徳永英樹, 八重樫伸生
    • Organizer
      第65回日本婦人科腫瘍学会 高得点演題
    • Data Source
      KAKENHI-PROJECT-21K09486
  • [Presentation] 当院における遺伝性乳癌卵巣癌症候群に対するリスク低減卵管卵巣摘出術の経験2022

    • Author(s)
      湊 純子,島田 宗昭, 萩原 達也, 橋本 栄文, 湊 敬道, 橋本 千明, 石橋 ますみ, 重田 昌吾, 永井 智之, 徳永 英樹, 八重樫 伸生
    • Organizer
      第74回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-21K09531
  • [Presentation] リスク低減卵管卵巣摘出術待機中にIIIA1(ii)期の卵管癌を発症した遺伝性乳癌卵巣癌症候群の一例2022

    • Author(s)
      村川 真理弥,湊 純子, 熊谷 奈津美, 萩原 達也, 橋本 栄文, 高橋 友梨, 栃木 実佳子, 橋本 千明, 石橋 ますみ, 重田 昌吾, 永井 智之, 徳永 英樹, 島田 宗昭, 八重樫 伸生
    • Organizer
      第151回東北連合産科婦人科学会総会
    • Data Source
      KAKENHI-PROJECT-21K09531
  • [Presentation] チロシンキナーゼ受容体型蛋白TIE-1の卵巣癌に対する抗腫瘍効果の検討2022

    • Author(s)
      石橋 ますみ,徳永 英樹, 重田 昌吾, 永井 智之, 島田 宗昭, 八重樫 伸生
    • Organizer
      第64回日本婦人科腫瘍学会
    • Data Source
      KAKENHI-PROJECT-21K09531
  • [Presentation] 進行卵巣癌における初回化学療法後の維持療法選択に関する後方視的検討2022

    • Author(s)
      橋本栄文,萩原 達也, 遠藤 俊, 清水 孝規, 湊 敬道, 湊 純子, 橋本 千明, 石橋 ますみ, 重田 昌吾, 徳永 英樹, 島田 宗昭, 八重樫 伸生
    • Organizer
      第74回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-21K09531
  • [Presentation] 卵巣癌既発症のBRCA病的バリアント保持者に対する乳房サーベイランスの現状2022

    • Author(s)
      湊 純子,島田 宗昭, 橋本 栄文, 萩原 達也, 湊 敬道, 橋本 千明, 石橋 ますみ, 重田 昌吾, 永井 智之, 徳永 英樹, 八重樫 伸生
    • Organizer
      第64回日本婦人科腫瘍学会
    • Data Source
      KAKENHI-PROJECT-21K09531
  • [Presentation] Functional analysis of ZFHX4 as a novel therapeutic target in ovarian cancer2020

    • Author(s)
      Yoshiko Oyama, Shigeta Shogo, Keita Tsuji, Muneaki Shimada, Nobuo Yaegashi
    • Organizer
      American Association for cancer research Annual Meeting 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09747
  • [Presentation] 卵巣明細胞腺癌におけるphosphatidylinositide 3-kinase (PI3K) - Akt経路およびARID1A蛋白発現と臨床的意義の検討2015

    • Author(s)
      大石徹郎、板持広明、近江奈央、庄子忠宏、嵯峨 泰、藤原寛行、島田宗昭、杉山 徹、鈴木光明、紀川純三、原田 省
    • Organizer
      第67回日本産科婦人科学会学術講演会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2015-04-09
    • Data Source
      KAKENHI-PROJECT-25462594
  • [Presentation] 卵巣明細胞腺癌におけるPI3K-Akt 経路およびARID1A 蛋白発現 と臨床的意義の検討2015

    • Author(s)
      大石徹郎、板持広明、庄子忠宏、嵯峨 泰、藤原寛行、島田宗昭、杉山 徹、鈴木光明、紀川純三、原田 省
    • Organizer
      第74回日本癌学会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25462594
  • [Presentation] Fibroblast growth factor receptor 2 is associated with poor overall survival in clear cell carcinoma of the ovary and may be a novel therapeutic approach.2015

    • Author(s)
      Itamochi H, Oumi N, Oishi T, Taniguchi F, Shoji T, Saga Y, Fujiwara H, Shimada M, Sugiyama T, Suzuki M, Kigawa J, Harada T.
    • Organizer
      106th Annual Meeting of the American Association for Cancer Research
    • Place of Presentation
      フィラデルフィア(アメリカ合衆国)
    • Year and Date
      2015-04-21
    • Data Source
      KAKENHI-PROJECT-24592517
  • 1.  TOKUNAGA Hideki (30595559)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 22 results
  • 2.  重田 昌吾 (90842633)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 12 results
  • 3.  SATO Syinya (10423261)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 4.  ITAMOCHI Hiroaki (20314601)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 5.  OISHI Tetsuro (80359877)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 6.  KIGAWA Junzo (00177784)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 7.  SATO Seiya (30621007)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 8.  HARADA Tasuku (40218649)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 9.  CHIKUMI Jun (70467702)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TARAKAWA Naoki (90163906)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TSUJI Keita (10835341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  YAEGASHI Nobuo (00241597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 13.  金森 康展 (70283984)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  高橋 正国 (30379622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  北谷 和之 (40539235)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  永井 智之 (00704298)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  安田 純 (00281684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  石橋 ますみ (20821383)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  菱沼 英史 (10824609)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 20.  平沢 晃 (90296658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  岡本 愛光 (20204026)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  NANIWA Jun
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 23.  YOSHIHARA Kousuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  BABA Tsukasa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  三上 幹男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  荻島 創一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  小杉 眞司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  城田 英和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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