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Osuka Koji  大須賀 浩二

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OOSUKA Kouzi  大須賀 浩二

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Researcher Number 40378013
Other IDs
Affiliation (Current) 2025: 愛知医科大学, 看護学部, 教授
Affiliation (based on the past Project Information) *help 2019 – 2025: 愛知医科大学, 看護学部, 教授
2014 – 2018: 愛知医科大学, 医学部, 教授
2010: 愛知医科大学, 医学部, 准教授
Review Section/Research Field
Principal Investigator
Basic Section 56010:Neurosurgery-related / Neurosurgery
Except Principal Investigator
Basic Section 59010:Rehabilitation science-related / Basic Section 56010:Neurosurgery-related / Neurosurgery / General internal medicine (including Psychosomatic medicine)
Keywords
Principal Investigator
apoptosis / 慢性硬膜下血腫 / シグナル伝達 / シグナル伝達系 / 歯髄幹細胞 / 脊髄損傷 / eotaxin-3 / 好酸球 / autophagy
Except Principal Investigator
光遺伝学 … More / アロディニア / 慢性痛 / ニューロモデュレーション / 脊髄刺激療法 / 歯髄幹細胞 / 再生医療 / 脊髄損傷 / 理学療法 / オプトジェネティクス / 身体不活動 / 予防 / 不活動 / 運動習慣 / 炎症性サイトカイン / IL-6 / JAK/STAT系 / 黄色靭帯 / 炎症 / JAK-STAT系 / 肥厚 / 黄色靱帯 / 腰部脊柱管狭窄症 / 施灸の脳科学 / 東洋医学 Less
  • Research Projects

    (9 results)
  • Research Products

    (77 results)
  • Co-Researchers

    (36 People)
  •  脊髄損傷後の歯髄幹細胞治療における活性化astrocyteでのapoptosisの発生機序の解明Principal Investigator

    • Principal Investigator
      大須賀 浩二
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Aichi Medical University
  •  Elucidation and application of mechanisms for pain signal induction and modulation caused by physical disuse

    • Principal Investigator
      大道 裕介
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kanazawa Medical University
  •  Development of a novel treatment for spinal cord injury combining spinal cord stimulation and dental pulp stem cells

    • Principal Investigator
      永島 吉孝
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Nagoya University
  •  脊髄損傷後の歯髄幹細胞治療の作用機序の解明と更なるadjuvant治療の確立Principal Investigator

    • Principal Investigator
      大須賀 浩二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Aichi Medical University
  •  運動習慣による病的疼痛の予防効果の検証とその機序の解明

    • Principal Investigator
      大道 美香
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kanazawa Medical University
  •  Clarification of eosinophilic chemoattractants in chronic subdural hematoma outer membranePrincipal Investigator

    • Principal Investigator
      Osuka Koji
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Aichi Medical University
  •  Elucidation of the inflammatory network system of the lumbar spinal canal in the patients with lumbar spinal canal stenosis

    • Principal Investigator
      YAMAHATA Hitoshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Kagoshima University
  •  Role of apoptosis in the spontaneous disappearance of chronic subdural hematomaPrincipal Investigator

    • Principal Investigator
      Osuka Koji
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Aichi Medical University
  •  Neuroscientific studies on the effect of moxibustion on chronic diseases

    • Principal Investigator
      USUDA Nobuteru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Fujita Health University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2011 2010 Other

All Journal Article Presentation

  • [Journal Article] Protective Mechanism of Stem Cells from Human Exfoliated Deciduous Teeth in Treating Spinal Cord Injury2024

    • Author(s)
      Nishii Tomoya、Osuka Koji、Nishimura Yusuke、Ohmichi Yusuke、Ohmichi Mika、Suzuki Chiharu、Nagashima Yoshitaka、Oyama Takahiro、Abe Takashi、Kato Hiroyuki、Saito Ryuta
    • Journal Title

      Journal of Neurotrauma

      Volume: - Issue: 9-10 Pages: 1196-1210

    • DOI

      10.1089/neu.2023.0251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09269
  • [Journal Article] Angiogenesis in the Outer Membrane of Chronic Subdural Hematomas through Thrombin-Cleaved Osteopontin and the Integrin α9 and Integrin β1 Signaling Pathways2023

    • Author(s)
      Koji Osuka, Yusuke Ohmichi, Mika Ohmichi, Satoru Honma, Chiharu Suzuki, Masahiro Aoyama, Kenichiro Iwami, Yasuo Watanabe and Shigeru Miyachi
    • Journal Title

      Biomedicine

      Volume: 11 Issue: 5 Pages: 1440-1440

    • DOI

      10.3390/biomedicines11051440

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09269, KAKENHI-PROJECT-21K16644
  • [Journal Article] 慢性硬膜下血腫被膜におけるintegrinα9β1シグナル伝達系の発現について2022

    • Author(s)
      大須賀 浩二、鈴木千春、青山正寛、岩味健一郎、大道裕介、大道美香、宮地 茂
    • Journal Title

      神経外傷

      Volume: 45 Pages: 39-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09269
  • [Journal Article] Sequential Expression of Chemokines in Chronic Subdural Hematoma Fluids after Trepanation Surgery2021

    • Author(s)
      Osuka Koji、Ohmichi Yusuke、Ohmichi Mika、Nakura Takahiro、Iwami Kenichiro、Watanabe Yasuo、Miyachi Shigeru
    • Journal Title

      Journal of Neurotrauma

      Volume: 38 Issue: 14 Pages: 1979-1987

    • DOI

      10.1089/neu.2020.7401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-21K16644
  • [Journal Article] Sequential expression of neutrophil chemoattractants in cerebrospinal fluid after subarachnoid hemorrhage2021

    • Author(s)
      Osuka Koji、Watanabe Yasuo、Suzuki Chiharu、Iwami Kenichiro、Miyachi Shigeru
    • Journal Title

      Journal of Neuroimmunology

      Volume: 357 Pages: 577610-577610

    • DOI

      10.1016/j.jneuroim.2021.577610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-21K16644
  • [Journal Article] Physical disuse contributes to widespread chronic mechanical hyperalgesia, tactile allodynia, and cold allodynia through neurogenic inflammation and spino-parabrachio-amygdaloid pathway activation.2020

    • Author(s)
      Ohmichi Y, Ohmichi M, Tashima R, Osuka K, Fukushige K, Kanikowska D, Fukazawa Y, Yawo H, Tsuda M, Naito M, Nakano T.
    • Journal Title

      Pain

      Volume: - Issue: 8 Pages: 1808-1823

    • DOI

      10.1097/j.pain.0000000000001867

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-19K22469, KAKENHI-PUBLICLY-18H05120, KAKENHI-PROJECT-19H03323, KAKENHI-PROJECT-19K11377, KAKENHI-PROJECT-20K21382, KAKENHI-PROJECT-19H05658, KAKENHI-PROJECT-17K01539
  • [Journal Article] Coordination between Calcium/Calmodulin-Dependent Protein Kinase II and Neuronal Nitric Oxide Synthase in Neurons2020

    • Author(s)
      Araki Shoma、Osuka Koji、Takata Tsuyoshi、Tsuchiya Yukihiro、Watanabe Yasuo
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 21 Pages: 7997-7997

    • DOI

      10.3390/ijms21217997

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-20K15983, KAKENHI-PROJECT-18K11083
  • [Journal Article] くも膜下出血後の髄液中における好中球誘発因子の経時的発現について2020

    • Author(s)
      大須賀浩二、宮地茂
    • Journal Title

      脳血管攣縮

      Volume: 36 Pages: 129-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] Expression of high mobility group B1 and toll-like receptor-nuclear factor κB signaling pathway in chronic subdural hematomas2020

    • Author(s)
      Osuka Koji、Watanabe Yasuo、Usuda Nobuteru、Iwami Kenichiro、Miyachi Shigeru、Takayasu Masakazu
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 6 Pages: e0233643-e0233643

    • DOI

      10.1371/journal.pone.0233643

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] Growing skull fracture with an atypical mechanism: a case report2020

    • Author(s)
      Aoyama M, Joko M, Niwa A, Iwami K, Hara M, Osuka K, Miyachi S.
    • Journal Title

      Nagoya Journal of Medical Science

      Volume: 82 Issue: 2 Pages: 377-381

    • DOI

      10.18999/nagjms.82.2.377

    • NAID

      120006847447

    • ISSN
      2186-3326
    • URL

      https://nagoya.repo.nii.ac.jp/records/30100

    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] Expression of Angiopoietins and Angiogenic Signaling Pathway Molecules in Chronic Subdural Hematomas2020

    • Author(s)
      Isaji Taiki、Osuka Koji、Ohmichi Yusuke、Ohmichi Mika、Naito Munekazu、Nakano Takashi、Iwami Kenichiro、Miyachi Shigeru
    • Journal Title

      Journal of Neurotrauma

      Volume: 37 Issue: 23 Pages: 2493-2498

    • DOI

      10.1089/neu.2020.7042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] Reliability of an Intraoperative Radiographic Anteroposterior View of the Spinal Midline for Detection of Pedicle Screws Breaching the Medial Pedicle Wall in the Thoracic, Lumbar, and Sacral Spine.2019

    • Author(s)
      Maejima R, Takeuchi M, Wakao N, Kamiya M, Aoyama M, Joko M, Osuka K, Takayasu M
    • Journal Title

      World Neurosurg

      Volume: 19 Pages: 18781892-18781892

    • DOI

      10.1016/j.wneu.2019.01.058

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09086, KAKENHI-PROJECT-17K10853
  • [Journal Article] Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage.2019

    • Author(s)
      van Dijk BJ, Meijers JCM, Kloek AT, Knaup VL, Rinkel GJE, Morgan BP, van der Kamp MJ, Osuka K, Aronica E, Ruigrok YM, van de Beek D, Brouwer M, Pekna M, Hol EM, Vergouwen MDI.
    • Journal Title

      Transl Stroke Res.

      Volume: - Issue: 4 Pages: 678-688

    • DOI

      10.1007/s12975-019-00757-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] ラットくも膜下出血後、海馬におけるSTAT3活性化の検討2019

    • Author(s)
      大須賀 浩二、大道 裕介、大道 美香、宮地 茂
    • Journal Title

      脳血管攣縮

      Volume: 35 Pages: 77-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] 慢性硬膜下血腫被膜におけるToll-like receptorシグナル伝達系の発現について2019

    • Author(s)
      大須賀 浩二、川口 礼雄、寺島 嗣明、宮地 茂
    • Journal Title

      神経外傷

      Volume: 42 Pages: 68-70

    • NAID

      130007691713

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] Expression of Autophagy Signaling Molecules in the Outer Membranes of Chronic Subdural Hematomas2019

    • Author(s)
      Osuka Koji、Watanabe Yasuo、Usuda Nobuteru、Aoyama Masahiro、Takeuchi Mikinobu、Takayasu Masakazu
    • Journal Title

      Journal of Neurotrauma

      Volume: 36 Issue: 2 Pages: 403-407

    • DOI

      10.1089/neu.2018.5626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] Subarachnoid hemorrhage induces neuronal nitric oxide synthase phosphorylation at Ser1412 in the dentate gyrus of the rat brain.2018

    • Author(s)
      K Wada, K Osuka, Y Watanabe, N Usuda, M Fukasawa, Y Araki, S Okamoto, T Wakabayashi
    • Journal Title

      Nitric Oxide

      Volume: 81 Pages: 67-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] Expressions of Eotaxin-3, Interleukin-5, and Eosinophil-Derived Neurotoxin in Chronic Subdural Hematoma Fluids2018

    • Author(s)
      Kawaguchi Reo、Osuka Koji、Aoyama Masahiro、Miyachi Shigeru、Takayasu Masakazu
    • Journal Title

      Journal of Neurotrauma

      Volume: 35 Issue: 19 Pages: 2242-2249

    • DOI

      10.1089/neu.2018.5646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Journal Article] Subarachnoid hemorrhage induces neuronal nitric oxide synthase phosphorylation at Ser 1412 in the dentate gyrus of the rat brain2018

    • Author(s)
      Wada Kentaro、Osuka Koji、Watanabe Yasuo、Usuda Nobuteru、Fukasawa Motoaki、Araki Yoshio、Okamoto Sho、Wakabayashi Toshihiko
    • Journal Title

      Nitric Oxide

      Volume: in press Pages: 67-74

    • DOI

      10.1016/j.niox.2017.10.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-26462174
  • [Journal Article] Ultrasonography has a diagnostic value in the assessment of cervical radiculopathy: A prospective pilot study.2017

    • Author(s)
      Takeuchi M, Wakao N, Hirasawa A, Murotani K, Kamiya M, Osuka K, Takayasu M.
    • Journal Title

      European Radiology

      Volume: 未定 Issue: 8 Pages: 3467-3473

    • DOI

      10.1007/s00330-016-4704-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10423, KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-15K20021
  • [Journal Article] Expression of Caspase Signaling Components in the Outer Membranes of Chronic Subdural Hematomas2017

    • Author(s)
      Osuka Koji、Watanabe Yasuo、Usuda Nobuteru、Aoyama Masahiro、Iwami Kenichiro、Takeuchi Mikinobu、Watabe Takeya、Takayasu Masakazu
    • Journal Title

      Journal of Neurotrauma

      Volume: 34 Issue: 22 Pages: 3192-3197

    • DOI

      10.1089/neu.2017.5051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10853, KAKENHI-PROJECT-26462174
  • [Journal Article] Expression of the JAK/STAT signaling pathway in the ligamentum flavum of patients with lumbar spinal canal stenosis.2017

    • Author(s)
      Yamahata H, Osuka K, Aoyama T, Yasuda M, Tokimura H, Arita K, Takayasu M.
    • Journal Title

      J Orthop Sci.

      Volume: 22 Issue: 2 Pages: 190-196

    • DOI

      10.1016/j.jos.2016.11.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-16K10790, KAKENHI-PROJECT-17K10853
  • [Journal Article] Activation of Nuclear Factor-kappa B in Endothelial Cells of Chronic Subdural Hematoma Outer Membranes.2017

    • Author(s)
      Osuka K, Watanabe Y, Usuda N, Aoyama M, Kawaguchi R, Takeuchi M, Takayasu M.
    • Journal Title

      Neurosurgery

      Volume: 80 Issue: 4 Pages: 571-578

    • DOI

      10.1093/neuros/nyw100

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-17K10853
  • [Journal Article] Inhibitory Mechanism of the Outer Membrane Growth of Chronic Subdural Hematomas.2017

    • Author(s)
      Osuka K, Watanabe Y, Usuda N, Aoyama M, Iwami K, Takeuchi M, Watabe T, Takayasu M.
    • Journal Title

      J Neurotrauma

      Volume: in press Issue: 11 Pages: 1996-2000

    • DOI

      10.1089/neu.2016.4623

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-17K10853
  • [Journal Article] Prevalence of C7 level anomalies at the C7 level: an important landmark for cervical nerve ultrasonography.2016

    • Author(s)
      Takeuchi M, Aoyama M, Wakao N, Tawada Y, Kamiya M, Osuka K, Matsuo N, Takayasu M
    • Journal Title

      Acta Radiol

      Volume: 57 Issue: 3 Pages: 318-324

    • DOI

      10.1177/0284185115579078

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Journal Article] Interleukin-6, MCP-1, IP-10, and MIG are sequentially expressed in cerebrospinal fluid after subarachnoid hemorrhage.2016

    • Author(s)
      Niwa A, Osuka K, Nakura T, Matsuo N, Watabe T, Takayasu M.
    • Journal Title

      J Neuroinflammation

      Volume: 30 Issue: 1 Pages: 217-217

    • DOI

      10.1186/s12974-016-0675-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Journal Article] Exploitation of Simple Classification and Space Created by the Tumor for the Treatment of Foramen Magnum Meningiomas.2016

    • Author(s)
      Yamahata H, Yamaguchi S, Takayasu M, Takasaki K, Osuka K, Aoyama M, Yasuda M, Tokimura H, Kurisu K, Arita K.
    • Journal Title

      World Neurosurg.

      Volume: 87 Pages: 1-7

    • DOI

      10.1016/j.wneu.2015.09.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Journal Article] Activation of STAT3 in endothelial cells of chronic subdural hematoma outer membranes.2016

    • Author(s)
      Osuka K, Watanabe Y, Usuda N, Aoyama M, Kawaguchi R, Watabe T, Takayasu M
    • Journal Title

      World Neurosurg

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Journal Article] Activation of signal transducer and activator of transcription 3 in endothelial cells of chronic subdural hematoma outer membranes2016

    • Author(s)
      Osuka K, Watanabe Y, Usuda N, Aoyama M, Kawaguchi R, Watabe T, Takayasu M.
    • Journal Title

      World Neurosurg

      Volume: 91 Pages: 376-382

    • DOI

      10.1016/j.wneu.2016.04.025

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26462174
  • [Journal Article] A Compaction Bone Grafting Technique Leads to Early Bone Fusion in Cases of Posterior Lumbar Interbody Fusion.2016

    • Author(s)
      Takeuchi M, Wakao N, Kamiya M, Hirasawa A, Hanamura S, Osuka K, Takayasu M.
    • Journal Title

      Neurosurgery

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Journal Article] Expression of Mitogen-Activated Protein Kinases in Chronic Subdural Hematoma Outer Membranes.2015

    • Author(s)
      Aoyama M, Osuka K, Usuda N, Watanabe Y, Kawaguchi R, Nakura T, Takayasu M
    • Journal Title

      J Neurotrauma

      Volume: 32 Issue: 14 Pages: 1064-1070

    • DOI

      10.1089/neu.2014.3594

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-25504016, KAKENHI-PLANNED-26111008
  • [Journal Article] Large volume inside the cage leading incomplete interbody bone fusion and residual back pain after posterior lumbar interbody fusion.2015

    • Author(s)
      Takeuchi M, Kamiya M, Wakao N, Hirasawa A, Kawanami K, Osuka K, Takayasu M.
    • Journal Title

      Neurosurg Rev

      Volume: 38 Issue: 3 Pages: 573-578

    • DOI

      10.1007/s10143-015-0610-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Journal Article] Lumbar extraforaminal entrapment: performance characteristics of detecting the foraminal spinal angle using oblique coronal MRI. A multicenter study.2015

    • Author(s)
      Takeuchi M, Wakao N, Kamiya M, Hirasawa A, Osuka K, Joko M, Kawanami K, Takayasu M
    • Journal Title

      Spine J

      Volume: 15 Issue: 5 Pages: 895-900

    • DOI

      10.1016/j.spinee.2015.02.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Journal Article] Increased ICP promotes CaMKII-mediated phosphorylation of neuronal NOS at Ser⁸⁴⁷ in the hippocampus immediately after subarachnoid hemorrhage.2015

    • Author(s)
      Makino K, Osuka K, Watanabe Y, Usuda N, Hara M, Aoyama M, Takayasu M, Wakabayashi T
    • Journal Title

      Brain Res

      Volume: 1616 Pages: 19-25

    • DOI

      10.1016/j.brainres.2015.04.048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174, KAKENHI-PROJECT-25504016
  • [Journal Article] Diagnostic accuracy of multifidus muscle spontaneous activity by needle electromyography for the detection of lumbar foraminal and lateral exit-zone stenosis.2015

    • Author(s)
      Takeuchi M, Wakao N, Kamiya M, Gosho M, Osuka K, Hirasawa A, Niwa A, Aoyama M, Kawaguchi R, Shima H, Takayasu M
    • Journal Title

      Eur Spine J

      Volume: 24 Issue: 10 Pages: 2281-2287

    • DOI

      10.1007/s00586-015-3846-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Journal Article] Expression of suppressor of cytokine signaling 3 in cerebrospinal fluid after subarachnoid hemorrhage2014

    • Author(s)
      Osuka K, Watanabe Y, Aoyama M, Nakura T, Matsuo N, Takayasu M.
    • Journal Title

      J Neuroinflammation

      Volume: 11 Issue: 1 Pages: 142-142

    • DOI

      10.1186/s12974-014-0142-2

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26462174
  • [Journal Article] Eotaxin-3 activates Smad through the TGF-β1 pathway in chronic subdural hematoma outer membranes.2014

    • Author(s)
      Osuka K, Watanabe Y, Usuda N, Aoyama M, Takeuchi M, Takayasu M.
    • Journal Title

      J Neurotrauma

      Volume: 31 Issue: 16 Pages: 1451-1456

    • DOI

      10.1089/neu.2013.3195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25504016, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26462174
  • [Journal Article] Expression of the JAK/STAT3/SOCS3 signaling pathway in herniated lumbar discs.2014

    • Author(s)
      Osuka K, Usuda N, Aoyama M, Yamahata H, Takeuchi M, Yasuda M, Takayasu M.
    • Journal Title

      Neurosci Lett

      Volume: 569 Pages: 55-58

    • DOI

      10.1016/j.neulet.2014.03.045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25504016, KAKENHI-PROJECT-26462174
  • [Journal Article] Activation of PI3 kinase/Akt signaling in chronic subdural hematoma outer membranes.2011

    • Author(s)
      Funai M, Osuka K, Usuda N, Atsuzawa K, Inukai T, Yasuda M, Watanabe Y, Takayasu M.
    • Journal Title

      J Neurotrauma. 28(in press)

    • Data Source
      KAKENHI-PROJECT-20390200
  • [Journal Article] Oxidative stress activates STAT1 in basilar arteries after subarachnoid hemorrhage.2010

    • Author(s)
      Osuka K, Watanabe Y, Usuda N, Atsuzawa K, Wakabayashi T, Takayasu M.
    • Journal Title

      Brain Res. 1332

      Pages: 12-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390200
  • [Journal Article] Oxidative stress activates STAT1 in basilar arteries after subarachnoid hemorrhage.2010

    • Author(s)
      Osuka K, et al.
    • Journal Title

      Brain Research

      Volume: 1332 Pages: 12-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390200
  • [Presentation] ヒト脱落乳歯由来幹細胞による脊髄損傷後の保護機構2023

    • Author(s)
      西井智哉, 大須賀浩二, 西村由介, 大道裕介, 永島吉孝, 雄山隆弘, 加藤寛之, 齋藤竜太
    • Organizer
      日本脳神経外科学会 第82回学術総会
    • Data Source
      KAKENHI-PROJECT-22K09269
  • [Presentation] 歯髄幹細胞を用いた脊髄神経再生研究2022

    • Author(s)
      西井智哉、西村由介、雄山隆弘、松尾衛、伊藤洋、永島吉孝、大須賀浩二、大道裕介、三谷泰之、齋藤竜太
    • Organizer
      第81回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09269
  • [Presentation] 慢性硬膜下血腫被膜血管新生におけるintegrin α9β1を介するシグナル伝達系の関与2021

    • Author(s)
      大須賀浩二、岩味健一郎、宮地茂、大道裕介、大道美香
    • Organizer
      第80回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] 慢性硬膜血腫被膜増大におけるOsteopontinならびにintegrin α9β1を介するシグナル伝達系の関与2021

    • Author(s)
      大須賀浩二、岩味健一郎、宮地茂、大道裕介、大道美香
    • Organizer
      第44回日本脳神経外傷学会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] くも膜下出血後の髄液中における好中球誘発因子の経時的発現について2020

    • Author(s)
      大須賀 浩二、宮地 茂
    • Organizer
      第79回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] くも膜下出血後の髄液中のおける好中球誘発因子の経時的発現について2020

    • Author(s)
      大須賀浩二、宮地茂
    • Organizer
      第36回スパズムシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] 術後慢性硬膜下血腫におけるchemokineの経時的な発現について2020

    • Author(s)
      大須賀浩二、川口礼雄、宮地茂
    • Organizer
      第43回日本脳神経外傷学会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] HMBG1 produces Interleukin-6 through the Toll-like receptor and NF-κB Signaling Pathway in Endothelial Cells of Chronic Subdural Hematoma2019

    • Author(s)
      Osuka K, Usuda N, Takayasu M
    • Organizer
      87th American Association of Neurological Surgeons Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] 慢性硬膜下血腫被膜増大におけるHMGB1ならびにToll-like receptorシグナル伝達系の関与2019

    • Author(s)
      大須賀浩二、高安正和、臼田信光
    • Organizer
      第42回日本脳神経外傷学会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] 術後慢性硬膜下血腫におけるchemokineの経時的な発現について2019

    • Author(s)
      大須賀 浩二、岩味 健一郎、川口 礼雄、宮地 茂
    • Organizer
      第78回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] くも膜下出血後のラット海馬におけるSTAT3の活性化について2019

    • Author(s)
      大須賀浩二、高安正和、和田健太郎
    • Organizer
      第35回スパズムシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] Activation of STAT3 in the CA1 and dentate gyrus after subarachnoid hemorrhage.2019

    • Author(s)
      Osuka K, Usuda N, Takayasu M
    • Organizer
      iSAH 2019 (15th International Conference on SubArachnoid Hemorrhage)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] 慢性硬膜下血腫被膜におけるAutophagyシグナル伝達系の発現2018

    • Author(s)
      大須賀浩二、川口礼雄、高安正和
    • Organizer
      第41回日本脳神経外傷学会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] くも膜下出血後のラット海馬におけるAkt/mTORシグナル伝達系の活性化について2018

    • Author(s)
      大須賀浩二、高安正和、和田健太郎
    • Organizer
      第34回スパズムシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] 慢性硬膜下血腫被膜におけるToll-like receptorシグナル伝達系の発現2018

    • Author(s)
      大須賀浩二、高安正和、臼田信光
    • Organizer
      第77回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] Expression of Autophagy Signaling Molecules in Chronic Subdural Hematoma Outer Membranes2018

    • Author(s)
      Koji Osuka, Nobuteru Usuda, Masakazu Takayasu
    • Organizer
      86th American Association of Neurological Surgeons Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] 慢性硬膜下血腫被膜におけるcaspaseシグナル伝達系の発現2017

    • Author(s)
      大須賀浩二、青山正寛、川口礼雄、高安正和、臼田信光
    • Organizer
      第40回日本脳神経外傷学会
    • Place of Presentation
      浅草
    • Year and Date
      2017-03-10
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] 慢性硬膜下血腫被膜におけるCaspaseシグナル伝達系の発現2017

    • Author(s)
      大須賀浩二、青山正寛、川口礼雄、高安正和
    • Organizer
      第40回日本脳神経外傷学会
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] Expression of Caspase Signaling Pathway in Chronic Subdural Hematoma Outer Membranes.2017

    • Author(s)
      Koji Osuka, Nobuteru Usuda, Mikinobu Takeuchi, Masakazu Takayasu
    • Organizer
      85th American Association of Neurological Surgeons Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] Expression of Caspase Signaling Pathway in Chronic Subdural Hematoma Outer Membranes2017

    • Author(s)
      Koji Osuka, Nobuteru Usuda, Mikinobu Takeuchi, Masakazu Takayasu
    • Organizer
      85th American Association of Neurological Surgeons Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] 慢性硬膜下血腫被膜におけるAutophagyシグナル伝達系の発現2017

    • Author(s)
      大須賀浩二、川口礼雄、渡部剛也、高安正和、臼田信光
    • Organizer
      第76回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] くも膜下出血後の髄液中のおける ケモカインの経時的発現について2017

    • Author(s)
      大須賀浩二、丹羽愛知、名倉崇弘、松尾直樹、渡部剛也、高安正和
    • Organizer
      第33回スパズムシンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2017-03-16
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] 慢性硬膜下血腫被膜におけるAutophagyシグナル伝達系の発現2017

    • Author(s)
      大須賀浩二、川口礼雄、渡部剛也、高安正和、臼田信光
    • Organizer
      第76回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] 慢性硬膜下血腫被膜におけるCaspaseシグナル伝達系の発現2017

    • Author(s)
      大須賀浩二、青山正寛、川口礼雄、高安正和、臼田信光
    • Organizer
      第40回日本脳神経外傷学会
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] くも膜下出血後の髄液中のおけるケモカインの経時的発現について2017

    • Author(s)
      大須賀浩二、名倉崇弘、松尾直樹、渡部剛也、高安正和、丹羽愛知
    • Organizer
      第33回スパズムシンポジウム
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] くも膜下出血後の髄液中のおけるケモカインの経時的発現について2017

    • Author(s)
      大須賀浩二、名倉崇弘、松尾直樹、渡部剛也、高安正和、丹羽愛知
    • Organizer
      第33回スパズムシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K10853
  • [Presentation] 慢性硬膜下血腫被膜におけるapoptosisの発現2016

    • Author(s)
      大須賀浩二、青山正寛、川口礼雄、高安正和
    • Organizer
      第75回日本脳神経外科学会総会
    • Place of Presentation
      博多
    • Year and Date
      2016-09-29
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] Inhibitory mechanism of chronic subdural hematoma outer membrane growth2016

    • Author(s)
      Koji Osuka;Nobuteru Usuda;Reo Kawaguchi;Masahiro Aoyama;Masakazu Takayasu
    • Organizer
      84th American Association of Neurological Surgeons Annual Scientific Meeting
    • Place of Presentation
      アメリカ シカゴ
    • Year and Date
      2016-04-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] 慢性硬膜下血腫被膜の 血管内皮におけるSTAT3の活性化について2016

    • Author(s)
      大須賀浩二、青山正寛、川口礼雄、高安正和、臼田信光
    • Organizer
      第39回日本脳神経外傷学会
    • Place of Presentation
      仙台
    • Year and Date
      2016-02-26
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] ラットくも膜下出血後脳底動脈における SOCS3とPIAS3の作用機序について2016

    • Author(s)
      大須賀浩二、高安正和、和田健太郎
    • Organizer
      第32回スパズムシンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] Activation of the NF-κB Signaling Pathway and STAT3 in Endothelial Cells of Chronic Subdural Hematoma2015

    • Author(s)
      Koji Osuka, Nobuteru Usuda, Masahiro Aoyama, Masakazu Takayasu
    • Organizer
      83rd AANS Annual Scientific meeting
    • Place of Presentation
      Washington, D.C.
    • Year and Date
      2015-05-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] Effect of Adiponectin on Cerebral Arteries after SAH2015

    • Author(s)
      Koji Osuka, Masakazu Takayasu
    • Organizer
      Vasospasm 2015
    • Place of Presentation
      Karuizawa
    • Year and Date
      2015-09-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] 慢性硬膜下血腫被膜の増大に対する 抑制機序について2015

    • Author(s)
      大須賀浩二、青山正寛、川口礼雄、高安正和
    • Organizer
      第74回日本脳神経外科学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2015-10-14
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] Phosphorylation of neuronal NOS at Ser847 in hippocampus immediately after subarachnoid hemorrhage

    • Author(s)
      Koji Osuka, Kazushige Makino, Masahiro Aoyama, Masakazu Takayasu
    • Organizer
      82ndAANS Annual Scientific meeting
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] 脊髄損傷後 神経細胞におけるシグナル伝達の経時的変化について

    • Author(s)
      大須賀浩二、青山正寛、竹内幹伸、上甲眞宏、安田宗義、高安正和
    • Organizer
      第29回日本脊髄外科学会
    • Place of Presentation
      東京
    • Year and Date
      2014-06-12 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-26462174
  • [Presentation] 慢性硬膜下血腫被膜におけるNF-kBシグナル伝達系の発現について

    • Author(s)
      大須賀浩二、青山正寛、川口礼雄、高安正和、臼田信光
    • Organizer
      第73回日本脳神経外科学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-10-09 – 2014-10-11
    • Data Source
      KAKENHI-PROJECT-26462174
  • 1.  大道 美香 (30581079)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 2.  大道 裕介 (50506673)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 3.  渡辺 泰男 (10273228)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  高安 正和 (60216794)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 45 results
  • 5.  西村 由介 (20447816)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 6.  USUDA Nobuteru (30135123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  SUGIYAMA Satoshi (50340229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NAGATSU Toshiharu (40064802)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MURAKAMI Kazuo (70110517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NAKAI Sachiko (30257836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  WATARI Nakazou (40079976)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NAGATSU Ikuko (80084573)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NAKAHARA Daiichirou (80128389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  HIGUCHI Susumu (40156576)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TAKAHASHI Hisahide (80084606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HATA Toshimichi (50399044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HAYASHI Takashi (80399328)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  FUKASAWA Motoaki (70387728)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ATSUZAWA Kimie (60387727)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 20.  MATSUZAWA Ayami (90273078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  YAMAZAKI Masao (10192395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  NAGAOKA Toshiharu (20021420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  OKAWARA Takeshi (20469034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SETOU Mitsutoshi (20302664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KANEKO Rina (70367697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  YAMAHATA Hitoshi (70589803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  平野 宏文 (00264416)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  有田 和徳 (90212646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  宮地 茂 (00293697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 30.  西園 啓文 (10502289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  池本 竜則 (40448387)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  林 寿来 (30533715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  永島 吉孝 (20867684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  種井 隆文 (30447817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  WAKAO Norimitsu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 36.  WATANABE Yasuo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 15 results

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