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Arahori Hitomi  荒堀 仁美

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荒堀 仁美  アラホリ ヒトミ

ARAHORI Hitomi  荒堀 仁美

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Researcher Number 40379186
Other IDs
Affiliation (Current) 2025: 大阪大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help 2017 – 2020: 大阪大学, 医学系研究科, 助教
2011 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教
2010: 大阪大学, 医学系研究科, 助教
2007: Osaka Univetsty, Faculty of medicine, assistant professor
2006: 大阪大学, 医学部附属病院, 医員(研究職)
2006: Osaka University Hospital, Perinatal center, Part-time Residfent, 医学部附属病院, 非常勤医員
2005: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Embryonic/Neonatal medicine / Pediatrics
Except Principal Investigator
Embryonic/Neonatal medicine / Pediatrics
Keywords
Principal Investigator
ゲノム編集 / iPS細胞 / ダウン症候群 / 造血 / 幹細胞 / 染色体異常 / ゲノム編集技術 / 染色体異常症候群 / 軟骨細胞 / 成長障害 … More / FGF23 (fibroblast growth factor) / FGF23 / Klotho / 骨代謝 / 新生児 / 未熟児くる病 … More
Except Principal Investigator
プロスタグランジンD2 / brain edema / prostaglandin D2 / hypoxic-ischemic injury / 脳浮腫 / 新生児低酸素性虚血性脳症 / Apoptois / Neuropathology / Prostaglandin D synthase / Astrocyte / Microglia / Neuroinflammation / Prostaglandin D2 / Demyelination / 脱髄 / アポトーシス / 神経病理 / プロスタグランジンD合成酵素 / アストロサイト / ミクログリア / 神経炎症 / 脱随 Less
  • Research Projects

    (5 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (5 People)
  •  Generation of disease-specific iPSC library for the identification of responsible genes in Down syndromePrincipal Investigator

    • Principal Investigator
      Arahori Hitomi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Analysis of disease mechanism of growth impairment in Down syndrome using human iPS cellsPrincipal Investigator

    • Principal Investigator
      ARAHORI HITOMI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Osaka University
  •  Analysis of Rickets in the premature baby using a new biomarker, FGF23 and KlothoPrincipal Investigator

    • Principal Investigator
      ARAHORI Hitomi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Osaka University
  •  The effect of prostaglandin D2 in neonatal hypoxic-ischemic injury

    • Principal Investigator
      WADA Kazuko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Osaka University
  •  Prostaglandin D_2 is a key molecule for neuroinflammation in the demyelinating diseases

    • Principal Investigator
      TANIIKE Masako
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University

All 2016 2014 2012 2011 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] Systematic cellular disease models reveal synergistic interactions of trisomy 21 and GATA1 mutations in hematopoietic abnormalities2016

    • Author(s)
      K. Banno, S. Omori, K. Hirata, N. Nawa, N. Nakagawa, K. Nishimura, M. Ohtaka, M. Nakanishi, T. Sakuma, T. Yamamoto, T. Toki, E. Ito, T. Yamamoto, C. Kokubu, J. Takeda, H. Taniguchi, H. Arahori, K. Wada, Y. Kitabatake and K. Ozono
    • Journal Title

      Cell Reports

      Volume: 15 Issue: 6 Pages: 1-15

    • DOI

      10.1016/j.celrep.2016.04.031

    • NAID

      120007135439

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461583, KAKENHI-PROJECT-14J04075, KAKENHI-PROJECT-24591601, KAKENHI-PROJECT-25461546, KAKENHI-PROJECT-25461643, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-15K15384, KAKENHI-PROJECT-26860799, KAKENHI-PROJECT-16K10090, KAKENHI-PROJECT-16K18478
  • [Journal Article] Serum concentrations of bevacizumab (avastin) and vascular endothelial growth factor in infants with retinopathy of prematurity.2012

    • Author(s)
      Sato T, Wada K, Arahori H, Kuno N, Imoto K, Iwahashi-Shima C, Kusaka S
    • Journal Title

      Am J Ophthalmol

      Volume: 153 Issue: 2 Pages: 327-333

    • DOI

      10.1016/j.ajo.2011.07.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791028, KAKENHI-PROJECT-23592597
  • [Journal Article] Circulating levels of soluble alpha-Klotho are markedly elevated in human umbilical cord blood2011

    • Author(s)
      Yasuhisa Ohata, Hitomi Arahori, Noriyuki Namba, Taichi Kitaoka, Haruhiko Hirai, Kazuko Wada, Masahiro Nakayama, Toshimi Michigami, Akihiro Imura, Yo-ichi Nabeshima, Yuji Yamazaki, and Keiichi Ozono
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791028
  • [Journal Article] Sonographic femur length to trunk cross area ratio: prediction of fetal outcome in 30 cases in which micromelia was suspected.2007

    • Author(s)
      Arahori H, Tamura A, Wasada K, Shimoya K, Wada K, Murata Y, Ozono K.
    • Journal Title

      J Obstet Gynaecol Res. 33(3)

      Pages: 284-53

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591218
  • [Journal Article] Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains2007

    • Author(s)
      Taniguchi, H, Okabe-Arahori, H, Wada, K, et. al.
    • Journal Title

      Neurosci lett 420(1)

      Pages: 39-44

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591218
  • [Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.2007

    • Author(s)
      Taniguchi H, Mohri I, Okabe-Arahori H, Aritake K, Wada K, Kanekiyo T, Narumiya S, Nakayama M, Ozono K, Urade Y, Taniike M.
    • Journal Title

      J Neurosci 27

      Pages: 4303-4312

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591085
  • [Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury2007

    • Author(s)
      Taniguchi, H, Okabe-Arahori, H, Wada, K, et. al.
    • Journal Title

      J Neurosci 27(16)

      Pages: 4308-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591218
  • [Journal Article] Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains.2007

    • Author(s)
      Taniguchi H, Okabe-Arahori H, Wada K, et. al.
    • Journal Title

      Neurosci Lett. 420(1)

      Pages: 39-44

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591218
  • [Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic in jury.2007

    • Author(s)
      Taniguchi H, Okabe-Arahori H, Wada K, et. al.
    • Journal Title

      J Neurosci. 27(16)

      Pages: 4303-12

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591218
  • [Journal Article] Sonographic femur length to trunk cross area ratio : prediction of fetal outcome in 30 cases in which micromelia was suspected2007

    • Author(s)
      Arahori, H, Tamura, A, Wasada, K, Shimoya, K, Wada, K, Murata, Y, Ozono, K
    • Journal Title

      J Obstet Gynaecol Res 33(3)

      Pages: 284-53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591218
  • [Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.2007

    • Author(s)
      Taniguchi H, Okabe-Arahori H, Wada K, et. al.
    • Journal Title

      J neurosci. 27(16)

      Pages: 4303-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591218
  • [Journal Article] CMV DNA detection in dried blood spots for diagnosing congenital CMV infection in Japan.2006

    • Author(s)
      Yamagishi Y, Wada K, Arahori H, Tamura A, et al.
    • Journal Title

      J Med Virol. 78(7)

      Pages: 923-925

    • Data Source
      KAKENHI-PROJECT-18591218
  • [Journal Article] Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains.

    • Author(s)
      Taniguchi H, Mohri I, Okabe-Arahori H, Kanekiyo T, Kagitani- Shimono K, Wada K, Urade Y, Nakayama M, Ozono K, Taniike M.
    • Journal Title

      Neurosci Lett (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591085
  • [Journal Article] Circulating Levels of Soluble α-Klotho Are Markedly Elevated in Human Umbilical Cord Blood

    • Author(s)
      Yasuhisa Ohata, Hitomi Arahori, ら
    • Journal Title

      The Journal of Clinical Endocrinology and Metabolism

      Volume: (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791028
  • [Presentation] 疾患特異的ヒトiPS細胞をもちいたダウン症候群の病態解析2014

    • Author(s)
      北畠 康司、坂野 公彦、大森 早也佳、平田 克弥、那波 伸敏、和田 和子、荒堀 仁美、谷口 英俊、大薗 恵一
    • Organizer
      第37回日本小児遺伝学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-04-10
    • Data Source
      KAKENHI-PROJECT-25461643
  • [Presentation] ダウン症候群における病態発症メカニズムの解明2014

    • Author(s)
      北畠 康司、坂野 公彦、平田 克弥、大森 早也佳、荒堀 仁美、松浪 桂、谷口 英俊、和田 和子、大薗 恵一
    • Organizer
      第117回日本小児科学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-04-11
    • Data Source
      KAKENHI-PROJECT-25461643
  • 1.  TANIIKE Masako (30263289)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  WADA Kazuko (30294094)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 3.  SAKAI Norio (30314313)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  田村 有広 (50379187)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  北畠 康司 (80506494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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