• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

HIRASHIMA MASANORI  平島 正則

… Alternative Names

HIRASHIMA Masanori  平島 正則

平島 正則  ヒラシマ マサノリ

Less
Researcher Number 40383757
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-0190-4381
Affiliation (Current) 2025: 新潟大学, 医歯学系, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 新潟大学, 医歯学系, 教授
2018: 神戸大学, 医学研究科, 非常勤講師
2016 – 2017: 神戸大学, 医学研究科, 准教授
2012 – 2015: 神戸大学, 医学(系)研究科(研究院), 准教授
2012: 神戸大学, 大学院・医学研究科, 准教授 … More
2010 – 2012: 神戸大学, 医学研究科, 准教授
2010: 神戸大学, 大学院・医学研究科, 准教授
2007: Kobe University, 医学系研究科, 准教授
2006: 慶應義塾大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biomedical structure and function and related fields / General anatomy (including histology/embryology) / Biological Sciences / General anatomy (including Histology/Embryology) / Developmental biology / Biological Sciences
Except Principal Investigator
Basic Section 56070:Plastic and reconstructive surgery-related / Basic Section 48010:Anatomy-related / Basic Section 54010:Hematology and medical oncology-related / Plastic surgery / General medical chemistry
Keywords
Principal Investigator
発生・分化 / 遺伝子変異 / マウス / 遺伝子 / リンパ管 / 胎生期浮腫 / 発生 / 動物 / 細胞・組織 / 解剖学 … More / 疾患モデル / 胎児 / 管腔形成 / 血管 / 形態形成学 / 発生学 … More
Except Principal Investigator
血小板 / リンパ浮腫 / リンパ管 / リンパ管内皮細胞 / リンパ節 / siRNA / 臨床モデル / リンパ管静脈吻合 / マウス / 血管 / リンパ洞フィルター / 細胞間相互作用 / 免疫応答 / 組織マクロファージ / 間質ストローマ細胞 / 抗体産生 / T細胞応答 / リンパ液フィルター / ストローマ細胞 / マクロファージ / リンパ洞 / 発生 / CLEC-2 / 異所性リンパ組織 / リンパ節発生 / ポドプラニン / プロスタノイド受容体 / プロスタノイド / マイクロサージェリー学 / 癲癇 / Rapl / 癩癇 / 雄性不妊 / 精子形成異常 / 帯状異所性灰白質症 / 神経細胞移動 / 血管形成 / ノックアウトマウス / グアニンヌクレオチド交換因子 / Rap1 / 低分子量G蛋白質 Less
  • Research Projects

    (13 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (29 People)
  •  マイクロサージェリーを用いないリンパ浮腫の外科治療を開発する

    • Principal Investigator
      田中 宏明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Niigata University
  •  リンパ管・血管分離を維持する血小板放出因子の作用機序

    • Principal Investigator
      椎谷 友博
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Niigata University
  •  血小板とリンパ管内皮細胞の相互作用を標的にした新たなリンパ浮腫治療の開発

    • Principal Investigator
      植木 春香
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Niigata University
  •  Molecular/cellular basis of lymphatic sinus filter in lymph node

    • Principal Investigator
      Katakai Tomoya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Niigata University
  •  A role of platelets in lymphoid tissue development: platelets as a cargo of bioactive substances

    • Principal Investigator
      Suzuki-INoue Katsue
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      University of Yamanashi
  •  A novel screen for mouse models of embryonic diseasePrincipal Investigator

    • Principal Investigator
      HIRASHIMA MASANORI
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Biomedical structure and function and related fields
    • Research Institution
      Kobe University
  •  Developmental mechanism and functional significance of physiological lymphovenous anastomosis.Principal Investigator

    • Principal Investigator
      Hirashima Masanori
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Kobe University
  •  リンパ管腔形成と維持におけるAspp1の役割と分子機構Principal Investigator

    • Principal Investigator
      平島 正則
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Pathology and molecular mechanism of embryonic edema in mice carrying endothelial gene mutationsPrincipal Investigator

    • Principal Investigator
      HIRASHIMA Masanori
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Kobe University
  •  Analysis of prostanoid receptors on lymphatic vessels

    • Principal Investigator
      NOMURA Tadashi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Kobe University
  •  Analysis of the function of Rap1-activating factors which mediate the cross-talks between different species of small G proteins

    • Principal Investigator
      KATAOKA Tohru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kobe University
  •  血管内皮細胞の動・静脈アイデンティティーを決定する細胞外環境Principal Investigator

    • Principal Investigator
      平島 正則
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
      Keio University
  •  マウス胚における動・静脈形成Principal Investigator

    • Principal Investigator
      平島 正則
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Developmental biology
    • Research Institution
      Kobe University
      Keio University

All 2023 2022 2018 2017 2016 2014 2013 2012 2011 2010 2009

All Journal Article Presentation

  • [Journal Article] From lymphatic endothelial cell migration to formation of tubular lymphatic vascular network2023

    • Author(s)
      Shiiya Tomohiro、Hirashima Masanori
    • Journal Title

      Frontiers in Physiology

      Volume: 14

    • DOI

      10.3389/fphys.2023.1124696

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06788
  • [Journal Article] Semaphorin 3G provides a repulsive guidance cue to lymphatic endothelial cells via Neuropilin-2/PlexinD1.2016

    • Author(s)
      Liu X, Uemura A, Fukushima Y, Yoshida Y, Hirashima M.
    • Journal Title

      Cell Rep

      Volume: 17 Issue: 9 Pages: 2299-2311

    • DOI

      10.1016/j.celrep.2016.11.008

    • NAID

      120005970748

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460253, KAKENHI-PROJECT-15K20260
  • [Journal Article] Flt1/VEGFR1 heterozygocity causes transient embryonic edema2016

    • Author(s)
      Otowa Y, Moriwaki K, Sano K, Shirakabe M, Yonemura S, Shibuya M, Rossant J, Suda T, Kakeji Y, Hirashima M
    • Journal Title

      Scientific Report

      Volume: 6 Issue: 1 Pages: 27186-27186

    • DOI

      10.1038/srep27186

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26460253, KAKENHI-PROJECT-16K20009
  • [Journal Article] Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice2012

    • Author(s)
      Keigo Sano, Osamu Katsuta, Satoshi Shirae, Yoshiaki Kubota, Masatsugu Ema, Toshio Suda, Masatsugu Nakamura, Masanori Hirashima
    • Journal Title

      Biochem Biophys Res Commun

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Journal Article] Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice2012

    • Author(s)
      Keigo Sano, Osamu Katsuta, Satoshi Shirae, Yoshiaki Kubota, Masatsugu Ema, Toshio Suda, Masatsugu Nakamura and Masanori Hirashima
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 420(2) Issue: 2 Pages: 422-427

    • DOI

      10.1016/j.bbrc.2012.03.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Journal Article] Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1.2009

    • Author(s)
      Kanemura, H., Satoh, T., Bilasy, S.E., Ueda, S., Hirashima, M., Kataoka, T.
    • Journal Title

      Biochem.Biophys.Res.Comm. 387

      Pages: 754-759

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390080
  • [Presentation] TGF-βは血小板を介したリンパ管と血管の分離にはたらく2022

    • Author(s)
      〇椎谷 友博、劉 シンイ、杉山 彰、吉松 康裕、平島 正則
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06788
  • [Presentation] Lymphatic vascular development and embryonic edema in mice.2018

    • Author(s)
      平島 正則
    • Organizer
      第40回日本血栓止血学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19526
  • [Presentation] リンパ管パターニングに関わるSemaphorin/Plexinシグナル2017

    • Author(s)
      平島正則
    • Organizer
      第122回日本解剖学会総会・全国学術集会
    • Place of Presentation
      長崎大学坂本キャンパス(長崎県長崎市)
    • Year and Date
      2017-03-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460253
  • [Presentation] リンパ管パターニングに関わるSemaphorin/Plexinシグナル2016

    • Author(s)
      平島正則
    • Organizer
      第40回日本リンパ学会総会
    • Place of Presentation
      東京大学 伊藤国際学術研究センター(東京都文京区)
    • Year and Date
      2016-06-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460253
  • [Presentation] Semaphorin 3G provides a repulsive guidance cue from arteries to Plexin D1+ lymphatic endothelial cells in mouse embryonic skin.2016

    • Author(s)
      Liu X, Uemura A, Fukushima Y, Yoshida Y, Hirashima M.
    • Organizer
      第24回日本血管生物医学会学術集会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2016-12-08
    • Data Source
      KAKENHI-PROJECT-26460253
  • [Presentation] Platelet activation blocks misconnection of lymphatic to blood vessels in mouse peripheral tissues by promoting lymphatic endothelial cell retraction via TGF-β signals.2016

    • Author(s)
      平島 正則
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460253
  • [Presentation] Aspp1 plays a crucial role in lymphatic vascular fusion and lymph-venous connection during mouse embryogenesis2014

    • Author(s)
      Kenta Mukai, Xinyi Liu, Kazumasa Moriwaki, Daiki Ikeda, Takashi Ueda, Masanori Hirashima
    • Organizer
      The 18th International Vascular Biology Meeting
    • Place of Presentation
      みやこめっせ(京都)
    • Data Source
      KAKENHI-PUBLICLY-24112513
  • [Presentation] Aspp1ノックアウトマウスにみられる胎生期浮腫とリンパ管形成異常2014

    • Author(s)
      平島 正則
    • Organizer
      第38回日本リンパ学会総会
    • Place of Presentation
      北里大学白金キャンパス薬学部コンベンションホール
    • Year and Date
      2014-06-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460253
  • [Presentation] リンパ管腔形成と維持におけるAspp1の役割2013

    • Author(s)
      平島 正則
    • Organizer
      平成 24 年度文部科学省新術領域研究 がん研究分野の特性等を踏まえた支援活動 公開シンポジウム
    • Place of Presentation
      学術総合センター(東京都)
    • Year and Date
      2013-01-29
    • Data Source
      KAKENHI-PUBLICLY-24112513
  • [Presentation] Aspp1 plays a crucial role in lymphatic vascular fusion and lymph-venous connection during mouse embryogenesis2013

    • Author(s)
      Masanori Hirashima, Xinyi Liu, Kazumasa Moriwaki, Daiki Ikeda
    • Organizer
      1st International Meeting for Epithelial Tubulology
    • Place of Presentation
      北海道大学学術交流会館(札幌)
    • Data Source
      KAKENHI-PUBLICLY-24112513
  • [Presentation] Aspp1 plays a crucial role in lymphatic vascular fusion and lymph-venous connection during mouse embryogenesis2013

    • Author(s)
      Masanori Hirashima, Kenta Mukai, Xinyi Liu, Kazumasa Moriwaki, Daiki Ikeda
    • Organizer
      第21回日本血管生物医学会学術集会
    • Place of Presentation
      千里阪急ホテル(大阪)
    • Data Source
      KAKENHI-PUBLICLY-24112513
  • [Presentation] 血小板はどのようにしてリンパ管網の独自性を守るのか2012

    • Author(s)
      平島 正則
    • Organizer
      日本リンパ学会
    • Place of Presentation
      東京女子医科大学(東京都)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] 血小板はどのようにしてリンパ管網の独自性を守るのか2012

    • Author(s)
      平島正則
    • Organizer
      第36回日本リンパ学会総会「シンポジウム・リンパ管の形成・機能の発現を左右する重要因子
    • Place of Presentation
      東京女子医科大学(東京都)
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] Platelets Contribute to the Separation between Blood Vessels and Lymphatic Vessels during Lymphatic Sprouting2011

    • Author(s)
      Guo Ding, Katsue Suzuki Inoue, Osamu Inoue, Masaki Hikida, Tomohiro Kurosaki, Masanori Hirashima
    • Organizer
      第19回日本血管生物医学会学術集会
    • Place of Presentation
      東京ステーションコンファレンス(東京都)
    • Year and Date
      2011-12-09
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] Platelets Contribute to the Separation between Blood Vessels and Lymphatic Vessels during Lymphatic Sprouting2011

    • Author(s)
      Guo Ding, Katsue Suzuki Inoue, Osamu Inoue, Masaki Hikida, Tomohiro Kurosaki, Masanori Hirashima
    • Organizer
      日本血管生物医学会
    • Place of Presentation
      東京ステーションコンファレンス(東京都)
    • Year and Date
      2011-12-09
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] 体液調節異常と胎生期浮腫をきたす遺伝子変異マウスの解析2010

    • Author(s)
      平島正則
    • Organizer
      日本人類遺伝学会第55回大会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      2010-10-29
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] 体液調節異常と胎生期浮腫をきたす遣伝子変異マウスの解析2010

    • Author(s)
      平島正則
    • Organizer
      日本リンパ学会
    • Place of Presentation
      東京大学山上会館(東京都)(招待講演)
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] 体液調節異常と胎生期浮腫をきたす遺伝子変異マウスの解析2010

    • Author(s)
      平島正則
    • Organizer
      日本人類遺伝学会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      2010-10-29
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] VEGF-A receptors in lymphatic vessel development and fluid homeostasis2010

    • Author(s)
      Masanori Hirashima
    • Organizer
      2010 International Cancer Biology Symposium
    • Place of Presentation
      国立中山大学(台湾)(招待講演)
    • Year and Date
      2010-06-28
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] 体液調節異常と胎生期浮腫をきたす遺伝子変異マウスの解析2010

    • Author(s)
      平島正則
    • Organizer
      第34回日本リンパ学会総会「シンポジウム・リンパ管新生の最前線」
    • Place of Presentation
      東京大学山上会館(東京都)
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-22590173
  • [Presentation] VEGF-A receptors in lymphatic vessel development and fluid homeostasis2010

    • Author(s)
      Masanori Hirashima
    • Organizer
      2010 International Cancer Biology Symposium
    • Place of Presentation
      国立中山大学(台湾)
    • Year and Date
      2010-06-28
    • Data Source
      KAKENHI-PROJECT-22590173
  • 1.  椎谷 友博 (80613190)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  田中 宏明 (80965260)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  松田 健 (50423166)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  LIU Xinyi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  KATAOKA Tohru (40144472)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  SATOH Takaya (20251655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  SHIMA FUMI (60335445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  EDAMATSU Hironori (70335438)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MORIWAKI Kazumasa (00467656)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  DING Guo (00514697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  NOMURA Tadashi (30529566)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HASHIKAWA Kazunobu (90403237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TERASHI Hiroto (80217421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SAKAKIBARA Shunsuke (50444592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Suzuki-INoue Katsue (10324211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Katakai Tomoya (00324682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  田原 真也 (60207206)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  若菜 茂晴 (90192434)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  田村 勝 (50370119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  築地 長治 (20710362)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  佐々木 知幸 (40739124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  白井 俊光 (50710381)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  奥田 修二郎 (00512310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  植木 春香 (10899933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OTOWA Yasunori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MUKAI Kenta
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  UETA Koji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  OGASAWARA Rina
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  須田 年生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi