Hoseki Jun 寳関淳

… Alternative Names

HOSEKI Jun 寳関淳

寶関淳ホウセキジュン

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Researcher Number	40423058
Other IDs
Affiliation (Current)	2025: 京都先端科学大学, バイオ環境学部, 教授
Affiliation (based on the past Project Information) *help	2019: 京都先端科学大学, バイオ環境学部, 准教授 2017 – 2018: 京都学園大学, バイオ環境学部, 准教授 2016: 京都大学, (連合)農学研究科(研究院), 特任准教授 2015 – 2016: 京都大学, 農学研究科, 特任准教授 2014: 京都大学, 生理化学研究ユニット, 准教授 … More 2012: 京都大学, 生理化学ユニット, 准教授 2011 – 2012: 京都大学, 生理化学研究ユニット, 特定准教授 2011: 京都大学, 生理化学研究ユニット, 准教授 Less
Review Section/Research Field	Principal Investigator Functional biochemistry Except Principal Investigator Applied biochemistry
Keywords	Principal Investigator 小胞体 / レドックス / グルタチオン / タンパク質品質管理 / タンパク質分解 / チオレドキシン / トランスポーター Except Principal Investigator レドックス / ケミカルバイオロジー / タンパク質代謝異常 … More / 蛍光タンパク質 / 分子シャペロン / ERdj5 / EDEM / ジスルフィド結合 / 小胞体品質管理 / 小胞体 / フォールディング / 品質管理 Less

Reducing power from cytosol controls ER protein quality controlPrincipal Investigator
- Principal Investigator
  
  Hoseki Jun
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyoto University of Advanced Science
Mechanism analysis of redox imbalance caused by aberrant proteostasis and its recovery using fluorescence protein sensors visualizing redox states.
- Principal Investigator
  
  Sakai Yasuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto University
Physiological role of reducing redox state near membrane in ER protein quality controlPrincipal Investigator
- Principal Investigator
  
  Hoseki Jun
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyoto University
ER redox regulation by ER GSH transporterPrincipal Investigator
- Principal Investigator
  
  HOSEKI Jun
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyoto University
Quality control mechanism of misfolded proteins
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Kyoto Sangyo University
  Kyoto University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 Other

All Journal Article Presentation Book

[Book] 酵母のレドックス認識機構を応用した新しいセンサータンパク質の開発2013
- Author(s)
  寳関淳、奥公秀、阪井康能
- Publisher
  FRAGRANCE JOURNAL
- Data Source
  KAKENHI-PROJECT-23770158
[Book] レドックス異常を回復する化合物レドックスモジュレーターの探索:Redoxfluorの創薬への利用2012
- Author(s)
  阪井康能、寳関淳、奥公秀
- Publisher
  遺伝子医学MOOK
- Data Source
  KAKENHI-PROJECT-23770158
[Journal Article] Synthesized Aβ42 Caused Intracellular Oxidative Damage, Leading to Cell Death, via Lysosome Rupture2017
- Author(s)
  Yuki Oku, Kazuma Murakami, Kazuhiro Irie, Jun Hoseki, and Yasuyoshi Sakai
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 42 Issue: 1 Pages: 71-79
- DOI
  10.1247/csf.17006
- NAID
  130005665696
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26292052, KAKENHI-PROJECT-26440050
[Journal Article] Development of a stable ERroGFP variant suitable for monitoring redox dynamics in the ER2016
- Author(s)
  J. Hoseki, A. Oishi, T. Fujimura and Y. Sakai
- Journal Title
  
  Bioscience Reports
  
  Volume: 36 Issue: 2
- DOI
  10.1042/bsr20160027
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440050, KAKENHI-PROJECT-26292052
[Journal Article] Screening of dietary antioxidants against mitochondria-mediated oxidative stress by visualization of intracellular redox state2016
- Author(s)
  S. Maharjan, Y. Sakai and J. Hoseki
- Journal Title
  
  Bioscience Biotechnology Biochemistry
  
  Volume: 80 Issue: 4 Pages: 726-734
- DOI
  10.1080/09168451.2015.1123607
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440050
[Journal Article] Screening of dietary antioxidants against mitochondria-mediated oxidative stress by visualization of intracellular redox state2016
- Author(s)
  S. Maharjan, Y. Sakai and J. Hoseki
- Journal Title
  
  Bioscience, Biotechonology and Biochemistry
  
  Volume: 80 Pages: 726-734
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26292052
[Journal Article] 細胞内レドックス状態の可視化によるレドックスモジュレーターの探索2015
- Author(s)
  寳関　淳，阪井康能
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 73 Pages: 198-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26440050
[Journal Article] プロテアソーム阻害が引き起こすレドックス異常と抗酸化食品成分による抑制2015
- Author(s)
  寳関　淳, 阪井康能
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 73 Pages: 192-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26440050
[Journal Article] Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition2014
- Author(s)
  Sunita Maharjan, Masahide Oku, Masashi Tsuda, Jun Hoseki and Yasuyoshi Sakai
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 5896-5896
- DOI
  10.1038/srep05896
- NAID
  120005462594
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292052, KAKENHI-PROJECT-26440050
[Journal Article] fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae2013
- Author(s)
  M. Oku, J. Hoseki, Y. Ichiki, and Y. Sakai.A
- Journal Title
  
  FEBS Lett.
  
  Volume: 587 Issue: 6 Pages: 793-798
- DOI
  10.1016/j.febslet.2013.02.003
- NAID
  120005244260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380052, KAKENHI-PROJECT-23651235, KAKENHI-PROJECT-23770158, KAKENHI-PROJECT-24780100
[Journal Article] Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj52011
- Author(s)
  M. Hagiwara, K. Maegawa, M. Suzuki, R. Ushioda, K. Araki, Y. Matsumoto, J. Hoseki, K. Nagata and K. Inaba
- Journal Title
  
  Mol. Cell
  
  Volume: 41(4) Issue: 4 Pages: 432-444
- DOI
  10.1016/j.molcel.2011.01.021
- NAID
  120003836694
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-23770158
[Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity2010
- Author(s)
  Y. Sugiura, K. Araki, 1 S. Iemura, T. Natsume,. J. Hoseki., K. Nagata
- Journal Title
  
  J. Biol. Chem 285(10)
  
  Pages: 7135-7142
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Solution structure and dynamics of mouse ARMET2010
- Author(s)
  J. Hoseki, H.Sasakawa, Y. Yamaguchi, M. Maeda, H. Kubota, K. Kato and K. Nagata
- Journal Title
  
  FEBS. Letters
  
  Volume: 584 Issue: 8 Pages: 1536-1542
- DOI
  10.1016/j.febslet.2010.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity2010
- Author(s)
  Y. Sugiura, K. Araki, S. Iemura, T. Natsume, J. Hoseki1 and K. Nagata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 285(10) Issue: 10 Pages: 7135-7142
- DOI
  10.1074/jbc.m109.082545
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER2008
- Author(s)
  R.Ushioda, J.Hoseki, K.Araki, G.Jansen, D.Y.Thomas and K.Nagata
- Journal Title
  
  Science
  
  Volume: 321(5888) Issue: 5888 Pages: 569-572
- DOI
  10.1126/science.1159293
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.2008
- Author(s)
  R. Ushioda, J. Hoseki, K. Araki, G. Jansen, D. Y. Thomas, K. Nagata
- Journal Title
  
  Science 321(5888)
  
  Pages: 569-572
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] メタノール資化性酵母 Candida boidinii における小胞体内酸化還元状態の解析2020
- Author(s)
  若林万紗也、由里本博也、寳関淳、阪井康能
- Organizer
  日本農芸化学会2020年大会
- Data Source
  KAKENHI-PROJECT-17K07332
[Presentation] メタノールセンサー宿主細胞を用いたメタン酸化触媒の開発2019
- Author(s)
  矢野龍一、竹谷友之、由里本博也、寳関　淳、緒方英明、嶋　盛悟、阪井康能
- Organizer
  日本農芸化学会2019年大会
- Data Source
  KAKENHI-PROJECT-17K07332
[Presentation] ERAD に必要なチオレドキシン由来の還元力伝達に伴う小胞体膜タンパク質の解析2018
- Author(s)
  田中　絵里子、寳関　淳、阪井　康能
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-17K07332
[Presentation] 小胞体でのミスフォールドタンパク質蓄積に伴うレドックス異常回復剤の同定とその機序について2017
- Author(s)
  奥　勇紀、奥野　友紀子、萩原　正敏、寳関　淳、阪井　康能
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学 (京都市)
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26440050
[Presentation] プロテアソーム阻害に伴う小胞体レドックス状態の還元機構2017
- Author(s)
  青木　健悟、藤村　多嘉朗、奥　勇紀、阪井　康能、寳関　淳
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-17K07332
[Presentation] レドックスが担うタンパク質恒常性の維持と異常2016
- Author(s)
  寳関　淳
- Organizer
  第11回レドックス・ライフイノベーションシンポジウム
- Place of Presentation
  お茶の水女子大学（東京都）
- Year and Date
  2016-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-26440050
[Presentation] 小胞体における異常タンパク質蓄積に伴うレドックス変化とこれを回復させる薬剤探索系の開発2016
- Author(s)
  寳関　淳、奥　勇紀、藤村　多嘉朗、大石　麻水、奥野　友紀子、萩原　正敏、阪井　康能
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ (京都市)
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26440050
[Presentation] 小胞体における異常タンパク質蓄積に伴うレドックス変化とこれを回復させる薬剤探索系の開発2016
- Author(s)
  寳関　淳、奥　勇紀、藤村　多嘉朗、大石　麻水、奥野　友紀子、萩原　正敏、阪井　康能
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ (京都市)
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] プロテアソーム阻害による異常タンパク質蓄積がミトコンドリア障害を惹起する機構2016
- Author(s)
  寳関　淳、Sunita Maharjan、阪井　康能
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ (京都市)
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26440050
[Presentation] プロテアソーム阻害による異常タンパク質がミトコンドリア障害を惹起する機構2016
- Author(s)
  寳関　淳、Sunita Maharjan、阪井　康能
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ (京都市)
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] プロテアソーム阻害に伴う鉄代謝異常・酸化ストレスとミトコンドリア障害2016
- Author(s)
  黒板　智博、Sunita Maharjan、寳関　淳、阪井　康能
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] The mechanisms underlying mitochondrial dysfunction under proteasome inhibition2015
- Author(s)
  Sunita Maharjan、黒板　智博、寳関　淳、阪井　康能
- Organizer
  BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会）
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] Intracellular Accumulation of Amyloid Beta Peptide Leads Lysosomal Membrane Permeabilization-Mediated Cell Death2015
- Author(s)
  Y. Oku, K. Murakami, K. Irie, J. Hoseki and Y. Sakai
- Organizer
  15th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants 2015
- Place of Presentation
  Paris, France
- Year and Date
  2015-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] Workshop “Visualization of Local Redox State in Cells: Its Application to Biology and Drug Screening”2015
- Author(s)
  Y. Sakai, M. Oku and J. Hoseki
- Organizer
  15th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants 2015
- Place of Presentation
  Paris, France
- Year and Date
  2015-06-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] 神経細胞内に蓄積したAβ42が細胞死を引き起こす機構2015
- Author(s)
  奥　勇紀、村上　一馬、入江　一浩、寳関　淳、阪井康能
- Organizer
  BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会）
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] The mechanism underlying mitochondrial dysfunction under proteasome inhibition2015
- Author(s)
  S. Maharjan, J. Hoseki and Y. Sakai
- Organizer
  Cold Spring Harbor Asia Conferences-Mitochondria
- Place of Presentation
  Suzhou, China
- Year and Date
  2015-10-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] プロテアソーム阻害に伴う小胞体レドックス異常の機序2015
- Author(s)
  藤村　多嘉朗、大石　麻水、Sunita Mahajan、寳関　淳、阪井　康能
- Organizer
  BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会）
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] プロテアソーム阻害に伴う小胞体レドックス異常の機序2015
- Author(s)
  藤村　多嘉朗、大石　麻水、Sunita Maharjan、寶関　淳、阪井康能
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440050
[Presentation] 小胞体関連分解における Trx2 の関与2015
- Author(s)
  上野　豊、奥　公秀、寳関　淳、阪井康能
- Organizer
  日本農芸化学会関西支部例会第488回講演会
- Place of Presentation
  京都市
- Year and Date
  2015-01-31
- Data Source
  KAKENHI-PROJECT-26440050
[Presentation] 酵母Saccharomyces ceruvisiaeにおけるペルオキシソーム内レドックス制御因子の解析2013
- Author(s)
  島並祐子、奥公秀、寳関淳、阪井康能
- Organizer
  日本農芸化学会関西支部第478回講演会
- Place of Presentation
  京都市
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Involvement in mitochondrial function by antioxidants protects cellular oxidation caused by proteasome inhibiton2013
- Author(s)
  Maharjan Sunita、寳関淳、奥公秀、阪井康能
- Organizer
  日本農芸化学会関西支部第478回講演会
- Place of Presentation
  京都市
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Glycosylation-Independent ERAD pathway serves as a backup system under ER stress2012
- Author(s)
  潮田亮、寳関淳、永田和宏
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会ワークショップ
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] 細胞内レドックス状態の可視化とこれを利用したレドックスモジュレーターの探索2012
- Author(s)
  寳関淳、阪井康能
- Organizer
  疾病予防・食品機能開発評価システムに関するフォーラム
- Place of Presentation
  京都市
- Year and Date
  2012-03-13
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Reduction mechanism of a disulfide reductase, ERdj5 in the oxidative redox environment of the ER2012
- Author(s)
  寳関淳、阪井康能、永田和宏
- Organizer
  Gordon Research Conferences: Thiol-Based Redox Regulation& Signaling
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Biochemical characterisation of Pfj2, a Plasmodium falciparum heat shock protein 40 chaperone potentially involved in protein quality control in the endoplasmic reticulum.2012
- Author(s)
  Omolola Afolayan, Eva-Rachele Pesce, Jun Hoseki, Shoshiro Hirayama, Kazuhiro Nagata, Caroline Knox and Gregory L. Blatch
- Organizer
  SASBMB/FASBMB Congress 2012
- Place of Presentation
  Drakensberg(South Africa)
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Glycosylation-independent ERAD pathway serves as a backup system under ER stress2012
- Author(s)
  Ryo Ushioda, Jun Hoseki, Kazuhiro Nagata
- Organizer
  EMBO/EMBL Symposium “Quality Control-From Molecules to Organelles”
- Place of Presentation
  Heiderberg(Germany)
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Reduction mechanism of a disulfide reductase, ERdj5 in the oxidative redox environment of the ER.2012
- Author(s)
  Jun Hoseki, Yasuyoshi Sakai, Kazuhiro Nagata
- Organizer
  Gordon Research Conferences: Thiol-Based Redox Regulation & Signaling
- Place of Presentation
  Lewiston, ME (USA)
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Glycosylation-independent ERAD pathway serves as a backup system under ER stress2012
- Author(s)
  潮田亮、寳関淳、永田和宏
- Organizer
  EMBO/EMBL Symposium "Quality Control-From Molecules to Organelles"
- Place of Presentation
  Germany
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Biochemical characterisation of Pfj2, a Plasmodium falciparum heat shock protein 40 chaperone potentially involved in protein quality control in the endoplasmic reticulum2012
- Author(s)
  Omolola Afolayan、Eva-Rachele Pesce、寳関淳、平山尚志郎、永田和宏、Caroline Knox、Gregory L. Blatch
- Organizer
  South African Society for Biochemistry and Molecular Biology/Federation of African Societies of Biochemistry and Molecular Biology SASBMB/FASBMB Congress 2012
- Place of Presentation
  South Africa
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] レドックス制御とタンパク質品質管理2012
- Author(s)
  寳関淳
- Organizer
  京都大学学際融合教育研究推進センター生理化学研究ユニット第2回シンポジウム
- Place of Presentation
  京都市
- Year and Date
  2012-06-13
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Non-glycoprotein ERAD pathway serves as a backup system under ER stress.2011
- Author(s)
  Ryo Ushioda, Jun Hoseki and Kazuhiro Nagata
- Organizer
  Cold Spring Harbor Asia Conference, "Protein Homeostasis in Health & Disease"
- Place of Presentation
  Suzhou(China)
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Non-glycoprotein ERAD pathway serves as a backup system under ER stress2011
- Author(s)
  潮田亮、寳関淳、永田和宏
- Organizer
  Cold Spring Harbor Asia Conference, "Protein Homeostasis in Health & Disease"
- Place of Presentation
  China
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] 糖たんぱく質ERADにおける ERdj5の役割/The role of ERdj5 in glycoprotein ERAD pathway.2011
- Author(s)
  萩原誠智、前川憲一、鈴木守、潮田亮、新木和孝、松本悠史、寳関淳、永田和宏、稲葉謙次
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] 糖たんぱく質ERADにおけるERdj5の役割/The role of ERdj5 in glycoprotein ERAD pathway2011
- Author(s)
  萩原誠智、前川憲一、鈴木守、潮田亮、新木和孝、松本悠史、寳関淳、永田和宏、稲葉謙次
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] ジスルフィド還元酵素ERdj5 による小胞体関連分解のレドックス制御2011
- Author(s)
  寳関淳
- Organizer
  第84回日本生化学会大会シンポジウム「レドックス反応システムによる細胞制御機構」
- Place of Presentation
  京都市
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23770158
[Presentation] Quality control & Redox regulatory network2010
- Author(s)
  K. Araki,R. Ushioda,J. Hoseki and K.Nagata
- Organizer
  Gordon Research Conference
- Place of Presentation
  Lucca (Italy)
- Year and Date
  2010-05-11
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Antioxidants derived from foods protect redox aberration and cell death caused by proteasome inhibition
- Author(s)
  Jun Hoseki
- Organizer
  Bordeaux-Kyoto
- Place of Presentation
  bordeaux (France)
- Year and Date
  2014-05-05 – 2014-05-06
- Invited
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] Stable ERroGFP variants are suitable for detection of ER redox state
- Author(s)
  Jun Hoseki, Asami Oishi and Yasuyoshi Sakai
- Organizer
  Gordon Research Conference, "Thiol-based redox regulation & signaling"
- Place of Presentation
  Girona (Spain)
- Year and Date
  2014-07-20 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] Mitochondria trigger cytosolic oxidative stress under proteasome inhibition
- Author(s)
  Sunita Maharjan, Masahide Oku, Jun Hoseki and Yasuyoshi Sakai
- Organizer
  Society for free radical biology and medicine's annual meeting 2014
- Place of Presentation
  Seatle (USA)
- Year and Date
  2014-11-19 – 2014-11-23
- Data Source
  KAKENHI-PROJECT-26292052
[Presentation] 小胞体関連分解における Trx2 の関与
- Author(s)
  上野　豊、奥　公秀、寳関　淳、阪井康能
- Organizer
  酵母遺伝学フォーラム第47回研究会
- Place of Presentation
  東京都
- Year and Date
  2014-09-01 – 2014-09-02
- Data Source
  KAKENHI-PROJECT-26440050

1. NAGATA Kazuhiro (50127114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. INABA Kenji (10423039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. HOSOKAWA Nobuko (00263153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Sakai Yasuyoshi (60202082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. OKU Masahide

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hoseki Jun 寳関 淳

HOSEKI Jun 寳関 淳

寶関 淳 ホウセキ ジュン

Research Projects

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Co-Researchers

Reducing power from cytosol controls ER protein quality controlPrincipal Investigator

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Mechanism analysis of redox imbalance caused by aberrant proteostasis and its recovery using fluorescence protein sensors visualizing redox states.

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Physiological role of reducing redox state near membrane in ER protein quality controlPrincipal Investigator

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ER redox regulation by ER GSH transporterPrincipal Investigator

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Quality control mechanism of misfolded proteins

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[Book] 酵母のレドックス認識機構を応用した新しいセンサータンパク質の開発2013

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[Book] レドックス異常を回復する化合物レドックスモジュレーターの探索:Redoxfluorの創薬への利用2012

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[Journal Article] Synthesized Aβ42 Caused Intracellular Oxidative Damage, Leading to Cell Death, via Lysosome Rupture2017

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[Journal Article] Development of a stable ERroGFP variant suitable for monitoring redox dynamics in the ER2016

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[Journal Article] Screening of dietary antioxidants against mitochondria-mediated oxidative stress by visualization of intracellular redox state2016

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[Journal Article] Screening of dietary antioxidants against mitochondria-mediated oxidative stress by visualization of intracellular redox state2016

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[Journal Article] 細胞内レドックス状態の可視化によるレドックスモジュレーターの探索2015

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[Journal Article] プロテアソーム阻害が引き起こすレドックス異常と抗酸化食品成分による抑制2015

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[Journal Article] Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition2014

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[Journal Article] fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae2013

Hoseki Jun 寳関淳

HOSEKI Jun 寳関淳

寶関淳ホウセキジュン