hirokawa yoshimi 広川美視

… Alternative Names

HIROKAWA Yoshimi 広川美視

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Researcher Number	40454582
Other IDs
Affiliation (Current)	2025: 大阪大谷大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2011 – 2018: 大阪大谷大学, 薬学部, 准教授 2007: Osaka Ohtani University, Faculty of Pharmacy, Associate Professor
Review Section/Research Field	Principal Investigator Drug development chemistry Except Principal Investigator Drug development chemistry / Chemical pharmacy
Keywords	Principal Investigator 創薬研究 / リューロムチリン / 多剤耐性菌 / 抗生物質 / 治癒効果 / リューロムチリン誘導体 / 天然物 / 創製研究 Except Principal Investigator 有機化学 / organic chemistry … More / biological activity / cancer / 生理活性 / 癌 / [2,3]-Wittig転位反応 / [2, 3]-Wittig転位反応 / 不斉合成 / リグナン / 抗酸化剤 Less

Synthesis and Antibacterial Activity of new compounds derived from natural antibioticsPrincipal Investigator
- Principal Investigator
  
  HIROKAWA YOSHIMI
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka Ohtani University
Design, Synthesis and Antibacterial Activity of Novel Pleuromutilin DerivativesPrincipal Investigator
- Principal Investigator
  
  HIROKAWA YOSHIMI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka Ohtani University
Development of antioxidant with lignan skeleton
- Principal Investigator
  
  MAEZAKI Naoyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka Ohtani University
Synthetic Study of HIF-1α Inhibitor, Manassantin B
- Principal Investigator
  
  MAEZAKI Naoyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Otani Womens University

All 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Bis(oxazoline)-ligand-mediated asymmetric[2, 3]-Wittig rearrangement of benzyl ethers : Reaction mechanism based on the hydrogen/deuterium exchange effect2012
- Author(s)
  M. Kitamura, Y. Hirokawa, Y. Yoshioka, and N. Maezaki
- Journal Title
  
  Tetrahedron
  
  Volume: 68(22) Issue: 22 Pages: 4280-4285
- DOI
  10.1016/j.tet.2012.03.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590032
[Journal Article] Total Synthesis of(+)-Eupomatilone 2 via Asymmetric[2, 3]-Wittig Rearrangement of Highly Oxygenated Biphenylmethyl Ethers2011
- Author(s)
  Y. Hirokawa, M. Kitamura, C. Kato, Y. Kurata, and N. Maezaki
- Journal Title
  
  Tetrahedron Lett
  
  Volume: 52(5) Issue: 5 Pages: 581-583
- DOI
  10.1016/j.tetlet.2010.11.126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590032
[Journal Article] Total Synthesis of(+)-Eupomatilone 2 via Asymmetric [2,3]-Wittig Rearrangement of Highly Oxygenated Biphenylmethyl Ethers2011
- Author(s)
  HIROKAWA, Yoshimi
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 52・5 Pages: 581-583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590032
[Journal Article] Asymmetric [2, 3]-Wittig Rearrangement of Oxygenated Allyl Benzyl Ethers in the Presence of a Chiral di-tBu-bis(oxazoline) Ligand : A Novel Synthetic Approach to THF Lignans2009
- Author(s)
  M. Kitamura, Y. Hirokawa, and N. Maezaki
- Journal Title
  
  Chem. Eur. J
  
  Volume: 15(38) Issue: 38 Pages: 9911-9917
- DOI
  10.1002/chem.200901212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590032
[Journal Article] Highly Enantioselective [2,3]-Wittig Rearrangement of Functionalized Allyl Benzyl Ethers:A Novel Approach to Lignan Synthesis2008
- Author(s)
  HIROKAWA, Yoshimi
- Journal Title
  
  Tetrahedron:Asymmetry (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590097
[Journal Article] Highly Enantioselective[2,3]-Wittig Rearrangement of Functionalized Allyl Benzyl Ethers:A Novel Approach to Ljgnan Synthesis2008
- Author(s)
  HIROKAWA, Yoshimi
- Journal Title
  
  Tetrahedron:Asymmetry (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590097
[Presentation] Synthesis and Antibacterial Activity of Novel Pleuromutilin Derivatives2013
- Author(s)
  Y. HIROKAWA*, M. KITAMURA, N. MAEZAKI.
- Organizer
  53th Interscience Conference on Antimicrobial Agents and Chemotherapy
- Place of Presentation
  COLORADO CONVENTION CENTER, DENVER, COLORADO, USA
- Data Source
  KAKENHI-PROJECT-23590139
[Presentation] 新規リューロムチリン誘導体の合成とその構造活性相関2013
- Author(s)
  広川美視、北村麻理愛、前﨑直容
- Organizer
  第３１回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ（広島市）
- Data Source
  KAKENHI-PROJECT-23590139
[Presentation] 不斉[2, 3]-Wittig転位反応を鍵反応としたeupomatilone類の不斉合成研究2012
- Author(s)
  水林誠, 北村麻理愛, 広川美視, 加藤千晴, 倉田祐希, 前崎直容
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] A Synthesis of Eupomatilones Using Enantioselective [2, 3]-Wittig Rearrangement2011
- Author(s)
  M. Kitamura, Y. Hirokawa, C. Kato, Y. Kurata, M. Mizubayashi, and N. Maezaki
- Organizer
  8th AFMC International Medicinal Chemistry Symposium Frontier of Medicinal Science
- Place of Presentation
  東京
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] Eupomatilone類縁体の合成研究2011
- Author(s)
  北村麻理愛, 広川美視, 前崎直容
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] 2, 5-ジアリールTHFリグナンの各種立体異性体の合成研究2011
- Author(s)
  守行美穂, 北村麻理愛, 広川美視, 前崎直容
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] 光学活性ビスオキサゾリン配位子を用いたベンジルエーテル類の不斉[2, 3]-Wittig転位反応の反応機構の考察2011
- Author(s)
  北村麻理愛, 吉岡勇輝, 広川美視, 前崎直容
- Organizer
  第37回反応と合成の進歩シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] Eupomatilone 2及びその類縁体の不斉合成2011
- Author(s)
  加藤千晴, 倉田祐希, 広川美視, 北村麻理愛, 前崎直容
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] Eupomatilone 2の合成2010
- Author(s)
  前崎直容, 加藤千晴, 倉田祐樹, 北村麻理愛, 広川美視
- Organizer
  第40回複素環化学討論会
- Place of Presentation
  仙台
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] 不斉[2, 3]-Wittig転位反応を鍵反応としたTHF-リグナン類の合成法の研究2010
- Author(s)
  広川美視, 北村麻理愛, 前崎直容
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] 不斉[2,3]-Wittig転位反応を鍵反応としたTHF-リグナン類の合成法の研究2010
- Author(s)
  広川美視, 北村麻理愛, 前崎直容
- Organizer
  日本薬学会第130年会
- Place of Presentation
  桃太郎アリーナ(岡山)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] Eupomatilone 2の不斉合成研究2010
- Author(s)
  北村麻理愛, 加藤千晴, 倉田祐樹, 広川美視, 前崎直容
- Organizer
  第60回日本薬学会近畿支部大会
- Place of Presentation
  大阪
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] ベンジルエーテル類の不斉[2,3]-Wittig転位反応-反応機構の考察-2009
- Author(s)
  前崎直容, 北村麻理愛, 広川美視
- Organizer
  第22回複素環化学討論会
- Place of Presentation
  さわやかちば県民プラザ(千葉)
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] 不斉[2,3]-Wittig転位反応を鍵反応としたリグナン類の系統的合成研究2009
- Author(s)
  北村麻理愛, 広川美視, 前崎直容
- Organizer
  第59回日本薬学会近畿支部大会
- Place of Presentation
  近畿大学(大阪)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] 不斉[2, 3]-Wittig転位反応を鍵反応としたリグナン類の系統的合成研究2009
- Author(s)
  北村麻理愛, 広川美視, 前崎直容
- Organizer
  第59回日本薬学会近畿支部大会
- Place of Presentation
  大阪
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] Application Of Enantioselective [2, 3]-Wittig Rearrangement To Construction Of Lignan Skeleton2009
- Author(s)
  北村麻理愛, 広川美視, 前崎直容
- Organizer
  第22回国際複素環化学会議
- Place of Presentation
  セント・ジョーンズ,カナダ
- Year and Date
  2009-08-05
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] ベンジルエーテル類の不斉[2, 3]-Wittig転位反応-反応機構の考察-2009
- Author(s)
  前崎直容, 北村麻理愛, 広川美視
- Organizer
  第39回複素環化学討論会
- Place of Presentation
  千葉
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21590032
[Presentation] Stereoselective Construction of 2, 5-Diaryl THF Lignan Skeleton2007
- Author(s)
  Yoshimi Hirokawa
- Organizer
  57th Annual Meeting of the Pharmaceutical Society of Japan Kinki Branch
- Place of Presentation
  Takatsuki
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590097
[Presentation] 2,5-ジアリールTHFリグナン骨格の立体選択的構築法の開発2007
- Author(s)
  広川美視
- Organizer
  第57回日本薬学会近畿支部大会
- Place of Presentation
  高槻
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590097
[Presentation] 2,5-ジアリールTHFリグナン骨格の立体選択的構築法の開発2007
- Author(s)
  広川美視
- Organizer
  第57回日本薬学会近畿支部大会
- Place of Presentation
  大阪薬科大学
- Year and Date
  2007-10-27
- Data Source
  KAKENHI-PROJECT-18590097

1. MAEZAKI Naoyoshi (00229296)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. KITAMURA Maria (00434811)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results

hirokawa yoshimi 広川 美視

HIROKAWA Yoshimi 広川 美視

Research Projects

Research Products

Co-Researchers

Synthesis and Antibacterial Activity of new compounds derived from natural antibioticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Design, Synthesis and Antibacterial Activity of Novel Pleuromutilin DerivativesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of antioxidant with lignan skeleton

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthetic Study of HIF-1α Inhibitor, Manassantin B

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Bis(oxazoline)-ligand-mediated asymmetric[2, 3]-Wittig rearrangement of benzyl ethers : Reaction mechanism based on the hydrogen/deuterium exchange effect2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Total Synthesis of(+)-Eupomatilone 2 via Asymmetric[2, 3]-Wittig Rearrangement of Highly Oxygenated Biphenylmethyl Ethers2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Total Synthesis of(+)-Eupomatilone 2 via Asymmetric [2,3]-Wittig Rearrangement of Highly Oxygenated Biphenylmethyl Ethers2011

Author(s)

Journal Title

Data Source

[Journal Article] Asymmetric [2, 3]-Wittig Rearrangement of Oxygenated Allyl Benzyl Ethers in the Presence of a Chiral di-tBu-bis(oxazoline) Ligand : A Novel Synthetic Approach to THF Lignans2009

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Highly Enantioselective [2,3]-Wittig Rearrangement of Functionalized Allyl Benzyl Ethers:A Novel Approach to Lignan Synthesis2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Highly Enantioselective[2,3]-Wittig Rearrangement of Functionalized Allyl Benzyl Ethers:A Novel Approach to Ljgnan Synthesis2008

Author(s)

Journal Title

Data Source

[Presentation] Synthesis and Antibacterial Activity of Novel Pleuromutilin Derivatives2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新規リューロムチリン誘導体の合成とその構造活性相関2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 不斉[2, 3]-Wittig転位反応を鍵反応としたeupomatilone類の不斉合成研究2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A Synthesis of Eupomatilones Using Enantioselective [2, 3]-Wittig Rearrangement2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Eupomatilone類縁体の合成研究2011

hirokawa yoshimi 広川美視

HIROKAWA Yoshimi 広川美視