tanaka shingo 田中慎吾

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TANAKA Shingo 田中慎吾

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Researcher Number	40507084
Affiliation (Current)	2025: 金沢大学, 附属病院, 助教
Affiliation (based on the past Project Information) *help	2024 – 2025: 金沢大学, 附属病院, 助教 2021 – 2023: 金沢大学, 医学系, 助教 2019: 金沢大学, 医学系, 助教 2018: 金沢大学, 附属病院, 特任助教 2017: 金沢大学, 大学病院, 特任助教 2013 – 2016: 金沢大学, 医学系, 協力研究員 2013: 金沢大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Neurosurgery / Basic Section 56010:Neurosurgery-related Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Cerebral neurosurgery
Keywords	Principal Investigator 膠芽腫 / RBPJ / Notchシグナル / 膠芽腫幹細胞 / グリオーマ幹細胞 / Notch阻害剤 / 腫瘍幹細胞形質転換 / 幹細胞 / Notch signal / RBPJｋ … More / Stat3 / RBPJk / STAT３ / STATシグナル / Akt阻害剤 / Akt阻害薬 / Notch阻害薬 / MRK-003 … More Except Principal Investigator 脳機能 / 血液 / バイオマーカー / エクソソーム / 予後判定 / 早期診断 / 血液バイオマーカー / 膠芽腫 / 分子標的治療 / グリオブラストーマ / GSK3beta / glioblastoma Less

Molecular basis of blood biomarkers inducing fundamental innovation in glioblastoma medicine
- Principal Investigator
  
  中田光俊
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
RBPJの発現レベルに影響される膠芽腫の細胞形質転換とテモゾロミドの反応性Principal Investigator
- Principal Investigator
  
  田中慎吾
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kanazawa University
The regulation of glioma stem cell by the transcription factor "RBPJ" suppression in Notch signalPrincipal Investigator
- Principal Investigator
  
  TANAKA SHINGO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kanazawa University
Complete regulation of glioma stem cell by notch and Akt signal inhibitionPrincipal Investigator
- Principal Investigator
  
  tanaka shingo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kanazawa University
The effect of the Notch inhibitor and a preclinical study for glioma stem cellsPrincipal Investigator
- Principal Investigator
  
  TANAKA Shingo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kanazawa University
Basic base constraction of malignant glioma therapy targeting for GSK3beta
- Principal Investigator
  
  MIYASHITA Katsuyoshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kanazawa University

All 2023 2022 2019 2018 2016 2015 2014 2013

All Journal Article Presentation Book

[Book] Clinical Neuroscience　脳腫瘍のゲノムとエピゲノム2018
- Author(s)
  田中慎吾、中田光俊
- Publisher
  中外医学社
- ISBN
- Data Source
  KAKENHI-PROJECT-17K10858
[Journal Article] α-SMA positive vascular mural cells suppress cyst formation in hemangioblastoma2023
- Author(s)
  Sakaguchi Maki、Nakajima Riho、Ichinose Toshiya、Tanaka Shingo、Kimura Ryouken、Sabit Hemragul、Nakada Satoko、Nakada Mitsutoshi
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 40 Issue: 3 Pages: 176-184
- DOI
  10.1007/s10014-023-00465-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00484, KAKENHI-PROJECT-23H05340
[Journal Article] Therapeutic potential of pentamidine for glioma‐initiating cells and glioma cells through multimodal antitumor effects2023
- Author(s)
  Tamai S, Ichinose T, Jiapaer S, Hirai N, Sabit H, Tanaka S, Kinoshita M, Kobayashi M, Hirao A, Nakada M.
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 7 Pages: 2920-2930
- DOI
  10.1111/cas.15827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-23K06629, KAKENHI-PROJECT-22H00484, KAKENHI-PROJECT-23K27437
[Journal Article] Symptomatic delayed in-stent thrombus formation after carotid artery stenting for radiation-induced stenosis: a case report2018
- Author(s)
  田中慎吾、東馬康郎、吉川陽文、木多眞也
- Journal Title
  
  Japanese Journal of Stroke
  
  Volume: 40 Issue: 5 Pages: 362-366
- DOI
  10.3995/jstroke.10555
- NAID
  130007486211
- ISSN
  0912-0726, 1883-1923
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10858
[Journal Article] Chronic spatial working memory deficit associated with the superior longitudinal fasciculus: a study using voxel-based lesion-symptom mapping and intraoperative direct stimulation in right prefrontal glioma surgery2016
- Author(s)
  Kinoshita K, Hayashi Y, et al.
- Journal Title
  
  J Neurosurg
  
  Volume: 19 Issue: 4 Pages: 1-19
- DOI
  10.3171/2015.10.jns1591
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462249, KAKENHI-PROJECT-15K19956, KAKENHI-PROJECT-15K19957
[Journal Article] Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report2015
- Author(s)
  Nakada M, Tanaka S, Oishi M, Miyashita K, Misaki K, Mohri M, Hayashi Ya, Uchiyama N, Watanabe T, Hayashi Yu
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 2 Issue: 1 Pages: 36-39
- DOI
  10.2176/nmccrj.2014-0080
- NAID
  130004698823
- ISSN
  2188-4226
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861263
[Journal Article] Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells2015
- Author(s)
  Tanaka S, Nakada M, Yamada D, Nakano I, Todo T, Ino Y, Hoshii T, Tadokoro Y, Ohta K, Ali MA, Hayashi Y, Hamada J, Hirao A.
- Journal Title
  
  J Neurooncol.
  
  Volume: 121 Issue: 2 Pages: 239
- DOI
  10.1007/s11060-014-1630-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25861263, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-26670638, KAKENHI-PROJECT-15K19548, KAKENHI-PROJECT-15K19956, KAKENHI-PROJECT-26253073
[Journal Article] Loss of Tsc1 accelerates malignant gliomagenesis when combined with oncogenic signals.2014
- Author(s)
  Yamada D, Hoshii T, Tanaka S, Hegazy AM, Kobayashi M, Tadokoro Y, Ohta K, Ueno M, Ali MAE, Hirao A.
- Journal Title
  
  J Biochem.
  
  Volume: 155 Issue: 4 Pages: 227-33
- DOI
  10.1093/jb/mvt112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25861263, KAKENHI-PROJECT-26460361
[Journal Article] Epithelioid glioblastoma arising from pleomorphic xanthoastrocytoma with the BRAF V600E mutation.2014
- Author(s)
  Tanaka S, Nakada M, Nobusawa S, Suzuki SO, Sabit H, Miyashita K, Hayashi Y.
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 31 Issue: 3 Pages: 172-6
- DOI
  10.1007/s10014-014-0192-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861263, KAKENHI-PROJECT-26293322
[Presentation] 外視鏡（ORBEYE）を用いた前頭蓋底腫瘍摘出術の視野限界2023
- Author(s)
  田中慎吾
- Organizer
  第35回日本頭蓋底外科学会
- Data Source
  KAKENHI-PROJECT-21K09145
[Presentation] 運動野内側近傍腫瘍に対する経硬膜刺激法を用いた下肢MEPモニタリングの有用性2023
- Author(s)
  田中慎吾
- Organizer
  第82回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09145
[Presentation] 難治性脊髄内胚葉性嚢胞に対するゴアテックス人工硬膜を使用した嚢胞開放術2023
- Author(s)
  田中慎吾
- Organizer
  第69回中部脊髄ワークショップ
- Data Source
  KAKENHI-PROJECT-21K09145
[Presentation] 聴神経腫瘍の味覚障害に関連する因子及び術前後の電気味覚検査の解析2023
- Author(s)
  田中慎吾
- Organizer
  第32回日本聴神経腫瘍研究会
- Data Source
  KAKENHI-PROJECT-21K09145
[Presentation] 脳腫瘍手術後の画像的変化を呈する早期合併症の解析2023
- Author(s)
  田中慎吾
- Organizer
  第28回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-21K09145
[Presentation] 膠芽腫病勢診断血液バイオマーカーAtaxin-2の検証2023
- Author(s)
  中田光俊、大槻純男、内田康雄、中嶋理帆、武笠晃丈、松﨑啓亮、篠山隆司、長嶋宏明、川端信司、矢木亮吉、立石健祐、長尾景充、齋藤紀彦、棗田学、田中將太、花谷亮典、廣瀬雄一、荒川芳輝、近藤聡英、石川栄一、吉本幸司、阿部竜也、黒住和彦、木下雅史、BIRD-DOG team
- Organizer
  第41回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00484
[Presentation] 積極的な助手参加型の外視鏡手術における病変と体位に応じた手術機器配置 ― 4 hands surgeryを目指して ―2023
- Author(s)
  田中慎吾
- Organizer
  第3回外視鏡手術研究会
- Data Source
  KAKENHI-PROJECT-21K09145
[Presentation] 積極的な助手参加型の外視鏡手術における病変と体位に応じた手術機器配置2023
- Author(s)
  田中慎吾
- Organizer
  第32回脳神経外科手術と機器学会
- Data Source
  KAKENHI-PROJECT-21K09145
[Presentation] 多施設共同研究による膠芽腫病勢診断血液バイオマーカーの同定2022
- Author(s)
  中田光俊、大槻純男、内田康雄、中嶋理帆、篠山隆司、長嶋宏明、立石健祐、齋藤紀彦、平井希、棗田学、塚本佳広、吉本幸司、花谷亮典、比嘉那優大、近藤聡英、石川栄一、武笠晃丈、廣瀬雄一、荒川芳輝、黒住和彦、阿部竜也、川端信司、田中將太、木下雅史、BIRD-DOG team
- Organizer
  第39回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00484
[Presentation] The regulation of the important nuclear transcription factor “RBPJ” of Notch signal in glioblastoma cells2019
- Author(s)
  Guangtao Zhang, Shingo Tanaka, Hemragul Sabit, Mitsutoshi Nakada
- Organizer
  ASNO 2019 The 16th Meeting of the Asian Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10858
[Presentation] Notchシグナル関連核内転写因子RBPJの抑制による抗膠芽腫細胞作用2019
- Author(s)
  張光濤、田中慎吾、淑瑠ヘムラサビット、中田光俊
- Organizer
  第20回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-17K10858
[Presentation] Analysis of prognostic factors in glioblastoma RPA class Ⅳ and Ⅴ2018
- Author(s)
  Shingo Tanaka, Masashi kinoshita M, Katsuyoshi Miyashita K, Mitsutoshi Nakada
- Organizer
  The 15th Meeting of the Asian Society for Neuro-Oncology,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10858
[Presentation] 小児テント上腫瘍の1例2018
- Author(s)
  田中慎吾、宮下勝吉、木下雅史、中田光俊
- Organizer
  第55回北陸脳腫瘍懇話会
- Data Source
  KAKENHI-PROJECT-17K10858
[Presentation] Notchシグナル活性化促進転写因子RBPJkの抑制による膠芽腫幹細胞悪性形質の制御2018
- Author(s)
  田中慎吾, 中田光俊
- Organizer
  第36回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10858
[Presentation] 充実性小脳虫部血管芽腫に対する3Dシミュレーション画像の有用性の検討2018
- Author(s)
  田中慎吾、宮下勝吉、中田光俊
- Organizer
  第23回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-17K10858
[Presentation] 段階的治療を施行した充実性小脳虫部頭側血管芽腫の１例2018
- Author(s)
  田中慎吾、宮下勝吉、木下雅史、見崎孝一、笹川泰生、内山尚之、林康彦、中田光俊
- Organizer
  第95回日本脳神経外科学会中部支部会
- Data Source
  KAKENHI-PROJECT-17K10858
[Presentation] 膠芽腫RPA分類クラス5における予後良好因子の検討2018
- Author(s)
  田中慎吾、宮下勝吉、玉井翔、木下雅史、中田光俊
- Organizer
  第77回脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10858
[Presentation] 膠芽腫幹細胞に対するγ－セクレターゼ阻害剤MRK003の効果と感受性マーカーの解析2015
- Author(s)
  田中慎吾、平尾敦、中野伊知郎、藤堂具紀、稲生靖、中田光俊
- Organizer
  第74回日本脳神経外科学術総会
- Place of Presentation
  札幌
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-15K19956
[Presentation] Notch阻害剤抵抗性膠芽腫幹細胞に対するAkt阻害剤併用の有効性2015
- Author(s)
  田中慎吾、中野伊知郎、平尾敦、中田光俊
- Organizer
  第33回日本脳腫瘍学会学術集会
- Place of Presentation
  京都
- Year and Date
  2015-12-06
- Data Source
  KAKENHI-PROJECT-15K19956
[Presentation] Mesenchymal type GBMに対するNotch阻害剤の有効性2013
- Author(s)
  田中慎吾、中田光俊、山田大祐、中野伊知郎、藤堂具紀、稲生靖、林裕、濵田潤一郎、平尾敦
- Organizer
  第31回日本脳腫瘍学会
- Place of Presentation
  宮崎シーガイア
- Data Source
  KAKENHI-PROJECT-25861263
[Presentation] 膠芽腫幹細胞株に対するγ‐セクレターゼ阻害剤MRK003の効果2013
- Author(s)
  田中慎吾、中田光俊、中野伊知郎、藤堂具紀、稲生靖、林裕、濵田潤一郎、平尾敦
- Organizer
  第72回日本脳神経外科学会総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25861263
[Presentation] Strong therapeutic potential of γ-secretase inhibitor MRK003 for GBM stem-like cells with high CD44 and low CD133 expression2013
- Author(s)
  Shingo Tanaka, Mitsutoshi Nakada, Daisuke Yamada, Ichiro Nakano, Tomoki Todo, Yutaka Hayashi, Jun-ichiro Hamada, Atsushi Hirao
- Organizer
  4th Quadrennial Meeting of the World Federation of Neuro-Oncology
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-25861263
[Presentation] Notch阻害による膠芽腫幹細胞の制御2013
- Author(s)
  田中慎吾、中田光俊、山田大祐、中野伊知郎、藤堂具紀、稲生靖、林裕、濵田潤一郎、平尾敦
- Organizer
  第14回日本分子脳神経外科学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25861263

1. NAKADA Mitsutoshi (20334774)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. FUROTA Takuya (20646690)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. MIYASHITA Katsuyoshi (80624874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大槻純男 (60323036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 内田康雄 (70583590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 木下雅史 (50525045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 中嶋理帆 (60614865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 平尾敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 林裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

tanaka shingo 田中 慎吾

TANAKA Shingo 田中 慎吾

Research Projects

Research Products

Co-Researchers

Molecular basis of blood biomarkers inducing fundamental innovation in glioblastoma medicine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RBPJの発現レベルに影響される膠芽腫の細胞形質転換とテモゾロミドの反応性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The regulation of glioma stem cell by the transcription factor "RBPJ" suppression in Notch signalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Complete regulation of glioma stem cell by notch and Akt signal inhibitionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of the Notch inhibitor and a preclinical study for glioma stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic base constraction of malignant glioma therapy targeting for GSK3beta

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Clinical Neuroscience 脳腫瘍のゲノムとエピゲノム2018

Author(s)

Publisher

ISBN

Data Source

[Journal Article] α-SMA positive vascular mural cells suppress cyst formation in hemangioblastoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic potential of pentamidine for glioma‐initiating cells and glioma cells through multimodal antitumor effects2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Symptomatic delayed in-stent thrombus formation after carotid artery stenting for radiation-induced stenosis: a case report2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Chronic spatial working memory deficit associated with the superior longitudinal fasciculus: a study using voxel-based lesion-symptom mapping and intraoperative direct stimulation in right prefrontal glioma surgery2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells2015

Author(s)

Journal Title

tanaka shingo 田中慎吾

TANAKA Shingo 田中慎吾

[Book] Clinical Neuroscience　脳腫瘍のゲノムとエピゲノム2018