Ishii Jun 石井純

… Alternative Names

ISHII Jun 石井純

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Researcher Number	40512546
Other IDs	https://orcid.org/0000-0003-2568-515X
Affiliation (Current)	2025: 神戸大学, 科学技術イノベーション研究科, 教授 2025: 神戸大学, 先端バイオ工学研究センター, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 神戸大学, 先端バイオ工学研究センター, 准教授 2017: 神戸大学, 大学院・科学技術イノベーション研究科, 教授 2015: 神戸大学, 学内共同利用施設等, 准教授 2015: 神戸大学, 自然科学系先端融合研究環重点研究部, 准教授 2014: 神戸大学, 自然科学系先端融合研究環, 准教授
Review Section/Research Field	Principal Investigator Basic Section 27040:Biofunction and bioprocess engineering-related / Biofunction/Bioprocess Except Principal Investigator Biofunction/Bioprocess
Keywords	Principal Investigator 酵母 / メタボライトセンサ / 進化工学 / 代謝工学 / 合成生物学 / レポーター遺伝子 / 発現スイッチ / 遺伝子発現スイッチ / アドレナリン受容体 / セロトニン受容体 … More / 二量体形成 / Gタンパク質共役型受容体 / Gタンパク質シグナル / ゲノム編集 / 遺伝子スイッチ … More Except Principal Investigator 酵母 / 代謝工学 / 出芽酵母 / メタボローム解析 / 代謝解析 / プロテオーム解析 / メタボローム分析 / 高級アルコール / Entner-doudoroff経路 / 中心代謝 / バイオ生産プロセス / 中心代謝経路 / 代謝シミュレーション / バイオプロダクション Less

Evolutionary engineering of yeast metabolisms using metabolite sensorsPrincipal Investigator
- Principal Investigator
  
  石井純
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Kobe University
Metabolic Engineering of yeast strains producing higher alcohols based on the precise metabolic characterization
- Principal Investigator
  
  Matsuda Fumio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Osaka University
Switching genome editing technology responding to G-protein signalingPrincipal Investigator
- Principal Investigator
  
  Ishii Jun
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Kobe University
Expansion of the central carbon metabolism in Saccharomyces cerevisiae
- Principal Investigator
  
  MATSUDA Fumio
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Osaka University

All 2023 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Patent

[Journal Article] ピキア酵母の多重遺伝子欠損による難分泌性抗体タンパク質の生産性向上2023
- Author(s)
  伊藤洋一郎，石井純，近藤昭彦
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 81 Pages: 234-236
- Data Source
  KAKENHI-PROJECT-23K26469
[Journal Article] Heterologous expression of bacterial phosphoenol pyruvate carboxylase and Entner?Doudoroff pathway in Saccharomyces cerevisiae for improvement of isobutanol production2017
- Author(s)
  Morita Keisuke、Nomura Yuta、Ishii Jun、Matsuda Fumio、Kondo Akihiko、Shimizu Hiroshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 124 Issue: 3 Pages: 263-270
- DOI
  10.1016/j.jbiosc.2017.04.005
- NAID
  40021323422
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06579
[Journal Article] Current Techniques for Studying Oligomer Formations of G-Protein-Coupled Receptors Using Mammalian and Yeast Cells2016
- Author(s)
  Yasuyuki Nakamura, Jun Ishii, Akihiko Kondo
- Journal Title
  
  Current Medicinal Chemistry
  
  Volume: 23 Issue: 16 Pages: 1605-1619
- DOI
  10.2174/0929867323666160407113353
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820362
[Journal Article] Overexpressing enzymes of the Ehrlich pathway and deleting genes of the competing pathway in Saccharomyces cerevisiae for increasing 2-phenylethanol production from glucose2016
- Author(s)
  Li Shen, Yuya Nishimura, Fumio Matsuda, Jun Ishii, and Akihiko Kondo
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 122 Issue: 1 Pages: 34-39
- DOI
  10.1016/j.jbiosc.2015.12.022
- NAID
  40020885810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06579
[Journal Article] Dual-color reporter switching system to discern dimer formations of G-protein-coupled receptors using Cre/loxP site-specific recombination in yeast2016
- Author(s)
  Yasuyuki Nakamura, Takamichi Hashimoto, Jun Ishii, Akihiko Kondo
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: in press Issue: 10 Pages: 2178-2190
- DOI
  10.1002/bit.25974
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820362
[Journal Article] Applications of yeast-based signaling sensor for characterization of antagonist and analysis of site-directed mutants of the human serotonin 1A receptor2015
- Author(s)
  Yasuyuki Nakamura, Jun Ishii, Akihiko Kondo
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 112 Issue: 9 Pages: 1906-1915
- DOI
  10.1002/bit.25597
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820362
[Journal Article] Eliminating the isoleucine biosynthetic pathway to reduce competitive carbon outflow during isobutanol production by Saccharomyces cerevisiae2015
- Author(s)
  Kengo Ida, Jun Ishii, Fumio Matsuda, Takashi Kondo, Akihiko Kondo
- Journal Title
  
  Microbial Cell Factories
  
  Volume: 14 Issue: 1 Pages: 62-62
- DOI
  10.1186/s12934-015-0240-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06579
[Journal Article] Gγ recruitment systems specifically select PPI and affinity-enhanced candidate proteins that interact with membrane protein targets2015
- Author(s)
  Misato Kaishima, Jun Ishii, Nobuo Fukuda & Akihiko Kondo
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 16723-16723
- DOI
  10.1038/srep16723
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J03862, KAKENHI-PROJECT-26820362
[Journal Article] Three gene expression vector sets for concurrently expressing multiple genes in Saccharomyces cerevisiae2014
- Author(s)
  石井純、近藤貴志、松田史生、近藤昭彦
- Journal Title
  
  FEMS Yeast research
  
  Volume: 14 Issue: 3 Pages: 399-411
- DOI
  10.1111/1567-1364.12138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25820400
[Journal Article] Signaling assays for detection of human G-protein-coupled receptors in yeast2014
- Author(s)
  Nakamura Y, Ishii J, Kondo A
- Journal Title
  
  Bio-protocol
  
  Volume: 4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26820362
[Journal Article] Increased isobutanol production in Saccharomyces cerevisiae by eliminating competing pathways and resolving cofactor imbalance2013
- Author(s)
  松田史生、石井純、近藤貴志、伊田賢吾、手塚裕紀、近藤昭彦
- Journal Title
  
  Microbial Cell Factories
  
  Volume: 12 Issue: 1 Pages: 119-119
- DOI
  10.1186/1475-2859-12-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25820400
[Journal Article] Regulation of central carbon metabolism in Saccharomyces cerevisiae by metabolic inhibitors2013
- Author(s)
  松田史生、白井智量、石井純、近藤昭彦
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 116 Issue: 1 Pages: 59-64
- DOI
  10.1016/j.jbiosc.2013.01.018
- NAID
  110009634746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25820400
[Patent] 高効率な酵母遺伝子系2023
- Inventor(s)
  冨永将大，石井純，近藤昭彦，堀智彦
- Industrial Property Rights Holder
  国立大学法人神戸大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-218699
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] T7ファージ由来の転写系を利用した酵母遺伝子スイッチの開発2023
- Author(s)
  堀智彦,冨永将大,梶亘佑,近藤昭彦,石井純
- Organizer
  神戸大学研究基盤センター若手フロンティア研究会2023
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] Development of genetic engineering tools for synthetic biology and cell factories in yeasts2023
- Author(s)
  Jun Ishii
- Organizer
  2023 Asian Synthetic Biology Association (ASBA) Meeting (ASBA2023)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] 酵母の高発現性人工誘導プロモータの開発2023
- Author(s)
  冨永将大,伊藤洋一郎,近藤昭彦,石井純
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] バクテリオファージ由来転写系を利用した酵母遺伝子スイッチの開発2023
- Author(s)
  堀智彦,冨永将大,梶亘佑,近藤昭彦,石井純
- Organizer
  第3回神戸大学先端バイオ工学研究センター成果発表会
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] 微生物代謝の理解と最適化に向けたバイオDX基盤の構築2023
- Author(s)
  石井純
- Organizer
  第75回日本生物工学会大会シンポジウム（生命科学研究の革新に向けたバイオDXの挑戦）
- Invited
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] バクテリオファージ由来RNAポリメラーゼを利用した酵母遺伝子スイッチの開発2023
- Author(s)
  堀智彦,冨永将大,梶亘佑,近藤昭彦,石井純
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] ピキア酵母におけるターミネーター置換での遺伝子発現量制御2023
- Author(s)
  伊藤洋一郎,寺井悟朗,石上美佐,橋場倫子,中村泰之,番場崇弘,雲北涼太,蓮沼誠久,浅井潔,石井純,近藤昭彦
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] バクテリオファージ由来の転写系を利用した酵母遺伝子スイッチの構築2023
- Author(s)
  堀智彦,冨永将大,梶亘佑,近藤昭彦,石井純
- Organizer
  日本農芸化学会関西支部第528回講演会
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] 高発現性の酵母人工誘導プロモータの開発2023
- Author(s)
  冨永将大,伊藤洋一郎,近藤昭彦,石井純
- Organizer
  第3回神戸大学先端バイオ工学研究センター成果発表会
- Invited
- Data Source
  KAKENHI-PROJECT-23K26469
[Presentation] ピルビン酸代謝フローの転換による出芽酵母2,3-ブタンジオール生産性の向上2017
- Author(s)
  森田啓介、松田史生、岡本浩二、石井純、近藤昭彦、清水浩
- Organizer
  第69回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-15K06579
[Presentation] マイトファジー抑制による出芽酵母の細胞質物質生産能力向上2017
- Author(s)
  森田啓介、松田史生、岡本浩二、石井純、近藤昭彦、清水浩
- Organizer
  日本農芸化学会 2017 大会
- Place of Presentation
  京都女子大学
- Data Source
  KAKENHI-PROJECT-15K06579
[Presentation] マイトファジー抑制による出芽酵母の細胞質物質生産能力向上2017
- Author(s)
  森田啓介、松田史生、岡本浩二、石井純、近藤昭彦、清水浩
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-15K06579
[Presentation] Heterologous gene expression in Saccharomyces cerevisiae for higher isobutanol production2016
- Author(s)
  Keisuke MORITA, Fumio MATSUDA, Jun ISHII, Akihiko KONDO, Hiroshi SHIMIZU
- Organizer
  Metabolic Engineering XI
- Place of Presentation
  淡路夢舞台
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06579
[Presentation] Engineering of mitochondrial isobutanol production in Saccharomyces cerevisiae2016
- Author(s)
  Keisuke Morita, Fumio Matsuda, Koji Okamoto, Kengo Ida, Jun Ishii, Akihiko Kondo, Hiroshi Shimizu
- Organizer
  14th International Congress on Yeasts
- Place of Presentation
  淡路夢舞台
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06579
[Presentation] イソブタノール生産酵母の構築：オルガネラ局在の検討2016
- Author(s)
  森田啓介、松田史生、伊田賢吾、石井純、近藤昭彦、清水浩
- Organizer
  第68回日本生物工学会大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-15K06579
[Presentation] 細胞質バリン生合成経路の異種発現による出芽酵母イソブタノール生産性の向上2016
- Author(s)
  森田啓介、松田史生、石井純、近藤昭彦、清水浩
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K06579
[Presentation] 2,3-ブタンジオール高生産出芽酵母株の構築2016
- Author(s)
  松田史生、伊田賢吾、木下翔平、森田啓介、石井寛子、石井純、近藤昭彦、清水浩
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K06579
[Presentation] 酵母シグナル伝達を用いた標的膜タンパク質に対するバイオメディカル分子スクリーニングシステム2015
- Author(s)
  海嶋美里，福田展雄，石井純，近藤昭彦
- Organizer
  第33回イーストワークショップ
- Place of Presentation
  せとうち児島ホテル
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-26820362
[Presentation] 1細胞スクリーニングに向けたヒトGPCRアッセイ用酵母バイオセンサー開発2015
- Author(s)
  橋弘樹，中村泰之，石井純，近藤昭彦
- Organizer
  生物工学若手研究者の集い夏のセミナー2015
- Place of Presentation
  タナベ名古屋研修センター
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-26820362
[Presentation] ヒトニューロテンシン受容体におけるリガンド探索のための酵母バイオセンサー2015
- Author(s)
  橋弘樹，中村泰之，石井純，近藤昭彦
- Organizer
  第67回日本生物工学会大会
- Place of Presentation
  鹿児島城山観光ホテル
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-26820362
[Presentation] ヒトニューロテンシン受容体のリガンド検出のための酵母バイオセンサーの開発2015
- Author(s)
  橋弘樹，中村泰之，石井純，近藤昭彦
- Organizer
  第33回イーストワークショップ
- Place of Presentation
  せとうち児島ホテル
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-26820362
[Presentation] High-resolution, quantitative analysis for measuring heterogeneities of G-protein signaling at single-cell levels in yeast2015
- Author(s)
  Jun Ishii, Akihiko Kondo
- Organizer
  The 2015 International Chemical Congress of Pacific Basin Societies (Pacifichem 2015)
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820362
[Presentation] 代謝シミュレーションにもとづく酵母イソブタノール生産能の向上2014
- Author(s)
  松田史生、石井純、近藤貴志、伊田賢吾、手塚裕紀、近藤昭彦
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-25820400
[Presentation] ＥＤ経路導入による酵母中心代謝経路の拡張2014
- Author(s)
  森田啓介、梶畠秀一、石井純、松田史生、清水浩
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-25820400
[Presentation] イソブタノール生産酵母におけるトランスヒドロゲナーゼ様シャントの活性化2013
- Author(s)
  石井純、松田史生、近藤貴志、近藤昭彦
- Organizer
  第65回日本生物工学会大会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-25820400
[Presentation] Gタンパク質共役型受容体の二量体形成検出のためのゲノム編集技術の開発
- Author(s)
  橋本貴理，中村泰之，石井純，近藤昭彦
- Organizer
  第66回日本生物工学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-09 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-26820362
[Presentation] G蛋白質共役型受容体の二量体形成に応答して機能するゲノム編集技術の開発
- Author(s)
  橋本貴理，中村泰之，石井純，近藤昭彦
- Organizer
  生物工学若手研究者の集い夏のセミナー2014
- Place of Presentation
  神戸市立神戸セミナーハウス
- Year and Date
  2014-07-12 – 2014-07-13
- Data Source
  KAKENHI-PROJECT-26820362

1. MATSUDA Fumio (50462734)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. MORITA Keisuke

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. NOMURA Yuta

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. NISHINO Shunsuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KINOSHITA Shohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Ishii Jun 石井 純

ISHII Jun 石井 純

Research Projects

Research Products

Co-Researchers

Evolutionary engineering of yeast metabolisms using metabolite sensorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Metabolic Engineering of yeast strains producing higher alcohols based on the precise metabolic characterization

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Switching genome editing technology responding to G-protein signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expansion of the central carbon metabolism in Saccharomyces cerevisiae

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ピキア酵母の多重遺伝子欠損による難分泌性抗体タンパク質の生産性向上2023

Author(s)

Journal Title

Data Source

[Journal Article] Heterologous expression of bacterial phosphoenol pyruvate carboxylase and Entner?Doudoroff pathway in Saccharomyces cerevisiae for improvement of isobutanol production2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Current Techniques for Studying Oligomer Formations of G-Protein-Coupled Receptors Using Mammalian and Yeast Cells2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overexpressing enzymes of the Ehrlich pathway and deleting genes of the competing pathway in Saccharomyces cerevisiae for increasing 2-phenylethanol production from glucose2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Dual-color reporter switching system to discern dimer formations of G-protein-coupled receptors using Cre/loxP site-specific recombination in yeast2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Applications of yeast-based signaling sensor for characterization of antagonist and analysis of site-directed mutants of the human serotonin 1A receptor2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Eliminating the isoleucine biosynthetic pathway to reduce competitive carbon outflow during isobutanol production by Saccharomyces cerevisiae2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gγ recruitment systems specifically select PPI and affinity-enhanced candidate proteins that interact with membrane protein targets2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Three gene expression vector sets for concurrently expressing multiple genes in Saccharomyces cerevisiae2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Signaling assays for detection of human G-protein-coupled receptors in yeast2014

Author(s)

Journal Title

Data Source

[Journal Article] Increased isobutanol production in Saccharomyces cerevisiae by eliminating competing pathways and resolving cofactor imbalance2013

Ishii Jun 石井純

ISHII Jun 石井純