Ohkubo Takeshi 大久保剛

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OHKUBO Takeshi 大久保剛

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Researcher Number	40513172
Other IDs	https://orcid.org/0000-0001-7591-5772
Affiliation (Current)	2025: 仙台白百合女子大学, 人間学部, 教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 仙台白百合女子大学, 人間学部, 教授 2021 – 2023: 仙台白百合女子大学, 人間学部, 准教授 2016: 仙台白百合女子大学, 人間学部, 准教授
Review Section/Research Field	Except Principal Investigator Basic Section 38050:Food sciences-related / Basic Section 59040:Nutrition science and health science-related / Integrated Nutrition Science / Eating habits
Keywords	Except Principal Investigator 小腸 / グリセロホスホジエステラーゼ / グリセロホスホコリン / コリン / リン脂質 / ゲノム編集法 / trimethylamine / 腸管上皮細胞特異的欠損マウス / trimethylamine N-oxide / choline … More / glycerophosphocholine / TMAO / GPC / GDE5 / Gpcpd1 / 消化管 / 酒粕 / ワンカーボン代謝 / コリン代謝 / n-3系脂肪酸 / 葉酸摂取 / 細胞間透過性 / 吸収 / ビタミンE / カロテノイド / Caco-2 / DHA / 小腸透過性 / 脂溶性ビタミン / リンパ輸送 / 消化 / 食塩摂取量 / 炭酸飲料 / 記憶の選択効果 / 基本五味 / 味覚刺激装置 / 苦味抑制 / 陰イオン効果 / 事象関連脳電位 / 味覚相互作用 / 舌 / 塩味 / 苦味 / 脳 / 味覚 Less

グリセロホスホコリン－吸収機構の解明から安全なコリン供給体として－
- Principal Investigator
  
  矢中規之
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Hiroshima University
Glycerophosphocholine as a choline source: its functions and absorption mechanism
- Principal Investigator
  
  Yanaka Noriyuki
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Hiroshima University
妊娠可能年齢女性を対象とした葉酸投与によるn-3系脂肪酸及びコリン代謝への影響
- Principal Investigator
  
  川端輝江
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagawa Nutrition University
taste information processing mechanism of brain
- Principal Investigator
  
  Suzuki Yuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Sendai Shirayuri Women's College
Influence of the chemical structure of dietary lipids on the bioavailability of coexistent food factors
- Principal Investigator
  
  MUROTA Kaeko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Kindai University

All 2024 2023 2022 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Role of Gpcpd1 in intestinal alpha-glycerophosphocholine metabolism and trimethylamine N-oxide production2024
- Author(s)
  Siyi Chen, Shiho Inui, Rahmawati Aisyah, Ryoko Nakashima, Tatsuya Kawaguchi, Minori Hinomoto, Yoshiko Nakagawa, Tetsushi Sakuma, Yusuke Sotomaru, Noriyasu Ohshima, Thanutchaporn Kumrungsee, Takeshi Ohkubo, Takashi Yamamoto, Yutaka Miura, Takuya Suzuki, Noriyuki Yanaka
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 12 Pages: 107965-107965
- DOI
  10.1016/j.jbc.2024.107965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21180, KAKENHI-PROJECT-24K02014
[Journal Article] Association of Fatty Acid Desaturase 1 rs174547 Polymorphism with the Composition of Long-Chain Polyunsaturated Fatty Acids in Serum Glycerophospholipids during Pregnancy2023
- Author(s)
  Kawabata Terue、Fukuoka Hideoki、Harada Michiru、Shoji Kumiko、Kubo Yoshinori、Mori Chisato、Sakurai Kenichi、Ohkubo Takeshi、Oshida Kyoichi、Yamashiro Yuichiro
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 3 Pages: 722-722
- DOI
  10.3390/nu15030722
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11837
[Journal Article] 脂質系栄養素：コリンの普及に際し、アメリカからの現状2017
- Author(s)
  日比野英彦、大久保　剛
- Journal Title
  
  脂質栄養学
  
  Volume: 26 Pages: 89-106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26350103
[Presentation] 妊娠期間中血清リン脂質中脂肪酸組成と食事・遺伝子多型及び妊娠週数との関連2022
- Author(s)
  川端輝江、原田みちる、庄司久美子、大久保剛、福岡秀興、森千里、櫻井健一、柳沢尚武、山城雄一郎
- Organizer
  日本脂質栄養学会第31回大会
- Data Source
  KAKENHI-PROJECT-22K11837
[Presentation] 食事性リン脂質の構成脂肪酸が腸管吸収過程における消化性に及ぼす影響2017
- Author(s)
  室田佳恵子、平野明伽音、渡辺嘉、大久保剛
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都府京都市（京都女子大学）
- Year and Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-26500020
[Presentation] DHA結合型ホスファチジルコリンが概日活動リズムに及ぼす影2016
- Author(s)
  大久保剛、立川直之、中村孝博
- Organizer
  日本脂質栄養学会
- Place of Presentation
  秋田市にぎわい交流館AU（あう）
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-26350103
[Presentation] ナノ粒子化加工によるビタミンEの吸収促進機構の解明2016
- Author(s)
  室田佳恵子、大塚芹、菅田望、村上陽子、伊佐治知也、寺尾純二、河田照雄、松村康生、大久保剛
- Organizer
  日本栄養・食糧学会第70回大会
- Place of Presentation
  兵庫県西宮市（武庫川女子大学）
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-26500020
[Presentation] Effect of nanoparticle processing on vitamin E absorption in human intestinal Caco-2 cells and rats2015
- Author(s)
  Kaeko Murota, Takeshi Ohkubo, Nozomi Sugata, Yoko Murakami, Rina Higashitani, Tomoya Isaji, Junji Terao, Teruo Kawada, Yasuki Matsumura
- Organizer
  The 6th International Conference on Food Factors
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26500020
[Presentation] Digestion and absorption of phospholipids as a dietary source of docosahexaenoic acid in rats2015
- Author(s)
  Kaeko Murota, Mika Takagi, Shun Kumamoto, Takeshi Ohkubo, Akira Tokumura
- Organizer
  12th Asian Congress of Nutrition
- Place of Presentation
  PACIFICO Yokohama, Yokohama, Japan
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26500020
[Presentation] ラットおよびヒトCaco-2細胞を用いた小腸におけるリン脂質消化吸収過程の解析2014
- Author(s)
  室田佳恵子、高木美佳、熊本舜、山川祥悟、岸野恵理佳、大久保剛、徳村彰
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学（北海道）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-26500020

1. MUROTA Kaeko (40294681)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. Yanaka Noriyuki (70346526)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Suzuki Yuichi (50091707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MATSUMURA Yasuki (50181756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 高澤まき子 (50289732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 渡邊兼行 (90337212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 菱沼宏哉 (20258792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山城秋美 (30722970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宮下ひろみ (20279607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 金澤寛明 (40214431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 唐木晋一郎 (00363903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 神田あづさ (40280086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 川端輝江 (80190932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 庄司久美子 (50721825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 藤井力 (40372198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 加藤久美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Ohkubo Takeshi 大久保 剛

OHKUBO Takeshi 大久保 剛

Research Projects

Research Products

Co-Researchers

グリセロホスホコリン－吸収機構の解明から安全なコリン供給体として－

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Glycerophosphocholine as a choline source: its functions and absorption mechanism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

妊娠可能年齢女性を対象とした葉酸投与によるn-3系脂肪酸及びコリン代謝への影響

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

taste information processing mechanism of brain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influence of the chemical structure of dietary lipids on the bioavailability of coexistent food factors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Role of Gpcpd1 in intestinal alpha-glycerophosphocholine metabolism and trimethylamine N-oxide production2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of Fatty Acid Desaturase 1 rs174547 Polymorphism with the Composition of Long-Chain Polyunsaturated Fatty Acids in Serum Glycerophospholipids during Pregnancy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 脂質系栄養素：コリンの普及に際し、アメリカからの現状2017

Author(s)

Journal Title

Data Source

[Presentation] 妊娠期間中血清リン脂質中脂肪酸組成と食事・遺伝子多型及び妊娠週数との関連2022

Author(s)

Organizer

Data Source

[Presentation] 食事性リン脂質の構成脂肪酸が腸管吸収過程における消化性に及ぼす影響2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] DHA結合型ホスファチジルコリンが概日活動リズムに及ぼす影2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ナノ粒子化加工によるビタミンEの吸収促進機構の解明2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Effect of nanoparticle processing on vitamin E absorption in human intestinal Caco-2 cells and rats2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Digestion and absorption of phospholipids as a dietary source of docosahexaenoic acid in rats2015

Author(s)

Organizer

Ohkubo Takeshi 大久保剛

OHKUBO Takeshi 大久保剛