Shirafuji Norimichi 白藤法道

Researcher Number	40529319
Other IDs
Affiliation (Current)	2025: 福井大学, 学術研究院医学系部門, 特別研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 福井大学, 学術研究院医学系部門, 特別研究員 2017 – 2021: 福井大学, 学術研究院医学系部門, 助教 2016: 福井大学, 学術研究院医学系部門(附属病院部), 医員 2013 – 2015: 福井大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator General internal medicine(including psychosomatic medicine) Except Principal Investigator Basic Section 52010:General internal medicine-related / General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator カスパーゼ / 高ホモシステイン血症 / サルコシル不溶性画分のタウ蛋白 / タウオパチー / 神経原線維変化 / タウ蛋白 / ホモシステイン Except Principal Investigator タウ蛋白 / アルツハイマー病 / オートファジー … More / オリゴマー / タウオリゴマー / タウ / GSK3β / p62 / LC3 / タウ蛋白リン酸化酵素 / タウ蛋白リン酸化 / クリオキノール / プロテアソーム / リン酸化 / バイオメタル / 老年医学 / 内科 / オリゴマータウ / ROCK阻害薬 / ピオグリタゾン / 神経細胞死 Less

Mechanisms of Tau oligomer formation by autophagy dysfunction.
- Principal Investigator
  
  濱野忠則
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  University of Fukui
Tau oligomerization by BioMetals
- Principal Investigator
  
  Hamano Tadanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  University of Fukui
Rho-kinase ROCK Inhibitors Reduce Oligomeric Tau Protein
- Principal Investigator
  
  Hamano Tadanori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Fukui
Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.Principal Investigator
- Principal Investigator
  
  Shirafuji Norimichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Fukui
Molecular mechanisms of Alzheimer's disease induced by oligomeric tau protein.
- Principal Investigator
  
  HAMANO TADANORI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Fukui

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Effectiveness of a self-reporting yes/no survey for dementia screening-trial in Fukui, Japan.2023
- Author(s)
  Hamano T, Nagata M, Matsubara R, Ikebata Y, Ito T, Ibe A, Fujita Y, Kusaka Y, Tokunaga T, Enomoto S, Endo Y, Ueno A, Shirafuji N, Ikawa M, Hayashi K, Yamamura O, Nakamoto Y.
- Journal Title
  
  Front Aging Neurosci.
  
  Volume: 14 Pages: 1029614-1029614
- DOI
  10.3389/fnagi.2022.1029614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07392
[Journal Article] Magnetic resonance imaging arterial spin labeling hypoperfusion with diffusion-weighted image hyperintensity is useful for diagnostic imaging of Creutzfeldt-Jakob disease.2023
- Author(s)
  Kitazaki Y, Ikawa M, Hamano T, Sasaki H, Yamaguchi T, Enomoto S, Shirafuji N, Hayashi K, Yamamura O, Tsujikawa T, Okazawa H, Kimura H, Nakamoto Y.
- Journal Title
  
  Front Neurol
  
  Volume: 14 Pages: 1242615-1242615
- DOI
  10.3389/fneur.2023.1242615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19505, KAKENHI-PROJECT-22K07392, KAKENHI-PROJECT-23K06924, KAKENHI-PROJECT-21K07616, KAKENHI-PROJECT-23K24278
[Journal Article] Regional cortical hypoperfusion and atrophy correlate with striatal dopaminergic loss in Parkinson's disease: a study using arterial spin labeling MR perfusion.2023
- Author(s)
  Kitazaki Y, Ikawa M, Yamaguchi T, Enomoto S, Shirafuji N, Yamamura O, Tsujikawa T, Okazawa H, Kimura H, Nakamoto Y, Hamano T.
- Journal Title
  
  Neuroradiology
  
  Volume: 65 Issue: 3 Pages: 569-577
- DOI
  10.1007/s00234-022-03085-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07392, KAKENHI-PROJECT-22K19505, KAKENHI-PROJECT-20K07900, KAKENHI-PROJECT-23K24278
[Journal Article] Rho-ROCK阻害薬によるタウ蛋白オリゴマー形成抑制2022
- Author(s)
  濵野忠則、白藤法道、山口智久、佐々木宏仁、中本安成
- Journal Title
  
  細胞
  
  Volume: 54 Pages: 50-54
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] Arterial spin labeling imaging for the detection of cerebral blood flow asymmetry in patients with corticobasal syndrome.2022
- Author(s)
  Yamaguchi T, Ikawa M, Enomoto S, Shirafuji N, Yamamura O, Tsujikawa T, Okazawa H, Kimura H, Nakamoto Y, Hamano T.
- Journal Title
  
  Neuroradiology.
  
  Volume: - Issue: 9 Pages: 1829-1837
- DOI
  10.1007/s00234-022-02942-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07909, KAKENHI-PROJECT-20K07900, KAKENHI-PROJECT-22K07392, KAKENHI-PROJECT-23K24278
[Journal Article] Influences of Vitamin B12 Supplementation on Cognition and Homocysteine in Patients with Vitamin B12 Deficiency and Cognitive Impairment.2022
- Author(s)
  Ueno A, Hamano T, Enomoto S, Shirafuji N, Nagata M, Kimura H, Ikawa M, Yamamura O, Yamanaka D, Ito T, Kimura Y, Kuriyama M, Nakamoto Y.
- Journal Title
  
  Nutrients.
  
  Volume: ;14(7): Issue: 7 Pages: 1494-1494
- DOI
  10.3390/nu14071494
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07909, KAKENHI-PROJECT-22K07392
[Journal Article] Persistent Severe Cerebral Edema with Neutrophil Infiltration Following<i> Listeria</i> Meningitis2022
- Author(s)
  Ueno A, Ikawa M, Maeda K, Tai K, Ito T, Shirafuji N, Yamamura O, Nakamoto Y, Hamano T.
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 22 Pages: 3431-3434
- DOI
  10.2169/internalmedicine.8291-21
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-11-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07392
[Journal Article] An exploratory, open-label, randomized, multicenter trial of hachimijiogan for mild Alzheimer’s disease2022
- Author(s)
  Kainuma M, Ouma S, Kawakatsu S, Iritani O, Yamashita KI, Ohara T, Hirano S, Suda S, Hamano T, Hieda S, Yasui M, Yoshiiwa A, Shiota S, Hironishi M, Wada-Isoe K, Sasabayashi D, Yamasaki S, Murata M, Funakoshi K, Hayashi K, Shirafuji N, Sasaki H, Kajimoto Y, Mori Y, Suzuki M, Ito H, Ono K, Tsuboi Y.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 991982-991982
- DOI
  10.3389/fphar.2022.991982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K07888, KAKENHI-PROJECT-21K07321, KAKENHI-PROJECT-22K07392, KAKENHI-PROJECT-22K07514, KAKENHI-PROJECT-22K15745, KAKENHI-PROJECT-20KK0193, KAKENHI-PROJECT-18K15509, KAKENHI-PROJECT-17K09211
[Journal Article] タウ蛋白とオートファジー.2021
- Author(s)
  濱野忠則，浅野礼，佐々木宏仁、山口智久，北﨑佑樹，遠藤芳徳，濱由香，白藤法道、中本安成.
- Journal Title
  
  細胞
  
  Volume: 53 Pages: 781-787
- NAID
  40022470680
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] オートファジーとタウオパチー．2021
- Author(s)
  *濱野忠則、山口智久、佐々木宏仁、白藤法道.
- Journal Title
  
  脳神経内科
  
  Volume: 95(4) Pages: 448-457
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] Clioquinol Decreases Levels of Phosphorylated, Truncated, and Oligomerized Tau Protein.2021
- Author(s)
  Lin G, Zhu F, Kanaan NM, Asano R, Shirafuji N, Sasaki H, Yamaguchi T, Enomoto S, Endo Y, Ueno A, Ikawa M, Hayashi K, Yamamura O, Yen SH, Nakamoto Y, Hamano T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22(21) Issue: 21 Pages: 12063-12063
- DOI
  10.3390/ijms222112063
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] Tau蛋白とオートファジー2021
- Author(s)
  濱野忠則、白藤法道, 佐々木宏仁, 山口智久, 遠藤芳徳, 武藤多津郎, 中本安成 Source：細胞 (1346-7557) Page44-46(2021.01) 抄録を見る所蔵確認
- Journal Title
  
  細胞
  
  Volume: 53巻1号 Pages: 44-46
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] Autophagy and Tau Protein.2021
- Author(s)
  Hamano T, Enomoto S, Shirafuji N, Ikawa M, Yamamura O, Yen SH, Nakamoto Y.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22(14) Issue: 14 Pages: 7475-7475
- DOI
  10.3390/ijms22147475
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] Autoimmune Encephalitis Associated with Anti-gamma-aminobutyric Acid B Receptor Antibodies Mimicking Syncope2020
- Author(s)
  Kitazaki Y, Ikawa M, Yamaguchi T, Enomoto S, Kishitani T, Shirafuji N, Hayashi K, Yamamura O, Nakamoto Y, Hamano T
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 6 Pages: 843-847
- DOI
  10.2169/internalmedicine.3652-19
- NAID
  130007808724
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-03-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] Influences of Folate Supplementation on Homocysteine and Cognition in Patients with Folate Deficiency and Cognitive Impairment.2020
- Author(s)
  Hama Y, Hamano T, Shirafuji N, Hayashi K, Ueno A, Enomoto S, Nagata M, Kimura H, Matsunaga A, Ikawa M, Yamamura O, Ito T, Kimura Y, Kuriyama M, Nakamoto Y.
- Journal Title
  
  Nutrients.
  
  Volume: 12(10): Issue: 10 Pages: 3138-3138
- DOI
  10.3390/nu12103138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] Rho-kinase ROCK inhibitors reduce oligomeric tau protein2020
- Author(s)
  Hamano T, Shirafuji N, Yen SH, Yoshida H, Kanaan NM, Hayashi K, Ikawa M, Yamamura O, Fujita Y, Kuruyama M, Nakamoto Y
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 89 Pages: 41-54
- DOI
  10.1016/j.neurobiolaging.2019.12.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19K07909
[Journal Article] An autopsy case of tuberculous meningitis undiagnosed by nested-PCR of CSF samples and brain biopsy.2020
- Author(s)
  Kitazaki Y, Ikawa M, Enomoto S, Shirafuji N, Hayashi K, Yamamura O, Yamada S, Arishima H, Noriki S, Nakamoto Y, Hamano T.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 415 Pages: 116968-116968
- DOI
  10.1016/j.jns.2020.116968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07909
[Journal Article] Subventricular glial nodules in neurofibromatosis 1 with craniofacial dysmorphism and occipital meningoencephalocele2019
- Author(s)
  Hamano Tadanori、Mutoh Tatsuro、Naiki Hironobu、Shirafuji Norimichi、Ikawa Masamichi、Yamamura Osamu、Dickson Dennis W.、Aiki Shichiryoemon、Kuriyama Masaru、Nakamoto Yasunari
- Journal Title
  
  eNeurologicalSci
  
  Volume: 17 Pages: 100213-100213
- DOI
  10.1016/j.ensci.2019.100213
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07513, KAKENHI-PROJECT-19K07909
[Journal Article] Homocysteine Increases Tau Phosphorylation,Truncation and Oligomerization.2018
- Author(s)
  Shirafuji N, Hamano T, Yen SH, Kanaan NM, Yoshida H, Hayashi K, Ikawa M,Yamamura O, Kuriyama M, Nakamoto Y.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19(3) Issue: 3 Pages: 17-17
- DOI
  10.3390/ijms19030891
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09235, KAKENHI-PROJECT-15K14343
[Journal Article] The Implications of Autophagy in Alzheimer's Disease.2018
- Author(s)
  Hamano T, Hayashi K, Shirafuji N, Nakamoto Y.
- Journal Title
  
  Curr Alzheimer Res.
  
  Volume: 15(14) Issue: 14 Pages: 1283-1296
- DOI
  10.2174/1567205015666181004143432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09235
[Journal Article] Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.2018
- Author(s)
  Norimichi Shirafuji,Tadanori Hamano
- Journal Title
  
  Molecular Sciences
  
  Volume: 19 Pages: 891-914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08904
[Journal Article] ROCK阻害薬によるタウ蛋白オリゴマー形成抑制機構2018
- Author(s)
  濱野忠則、白藤法道、林浩嗣、佐々木宏仁、中本安成
- Journal Title
  
  アグリバイオ
  
  Volume: 2(8) Pages: 790-794
- NAID
  40021807815
- Data Source
  KAKENHI-PROJECT-16K09235
[Journal Article] Rho-ROCK阻害薬によるタウ蛋白オリゴマー形成抑制機構の解明2018
- Author(s)
  濱野忠則、白藤法道、林浩嗣、佐々木宏仁、中本安成.
- Journal Title
  
  細胞
  
  Volume: 50(6) Pages: 340-343
- Data Source
  KAKENHI-PROJECT-16K09235
[Journal Article] Rho-ROCK阻害薬によるタウ蛋白オリゴマー形成抑制機構の解明2018
- Author(s)
  濱野忠則、白藤法道、林浩嗣、佐々木宏仁、中本安成
- Journal Title
  
  細胞
  
  Volume: 50 Pages: 340-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09235
[Journal Article] A case of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody-positive paraneoplastic necrotizing myopathy associated with advanced gastric cancer that responded to intravenous immunoglobulin therapy2017
- Author(s)
  Yamaguchi T, Matsunaga A, Ikawa M, Shirafuji N, Nishino I, Hamano T.
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 57 Issue: 3 Pages: 118-123
- DOI
  10.5692/clinicalneurol.cn-000982
- NAID
  130005494165
- ISSN
  0009-918X, 1882-0654
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09235
[Journal Article] A case of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody-positive paraneoplastic necrotizing myopathy associated with advancee gastric cancer that responded to intravenous immunoglobulin therapy.2017
- Author(s)
  Yamaguchi T,Matsunaga A,Ikawa M,Shirafuji N
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 28 Pages: 118-123
- Open Access
- Data Source
  KAKENHI-PROJECT-15K08904
[Journal Article] Pioglitazone prevents tau oligomerization.2016
- Author(s)
  Hamano T, Shirafuji N, Makino C, Yen SH, Kanaan NM, Ueno A, Suzuki J, Ikawa M, Matsunaga A, Yamamura O, Kuriyama M, Nakamoto Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 478 Issue: 3 Pages: 1035-1042
- DOI
  10.1016/j.bbrc.2016.08.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461360, KAKENHI-PROJECT-15K08904, KAKENHI-PROJECT-16K09235
[Journal Article] アルツハイマー病とホモシステイン2014
- Author(s)
  濱野忠則、白藤法道、栗山　勝、中本安成
- Journal Title
  
  ビタミン
  
  Volume: ８８（２） Pages: 92-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460893
[Journal Article] アルツハイマー病とホモシステイン2014
- Author(s)
  濱野忠則, 白藤法道, 栗山勝, 中本安成
- Journal Title
  
  ビタミン
  
  Volume: 88巻2号 Pages: 92-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460893
[Journal Article] Hashimoto's encephalopathy presenting periodic synchronous discharge, as a differential diagnosis for Creutzfeldt-Jakob disease.2013
- Author(s)
  Muramatsu T, Hamano T, Shirafuji N, Matsunaga A, Ikawa M, Yoneda M.
- Journal Title
  
  Rinsho Shinkeigaku.
  
  Volume: 53 Pages: 716-720
- NAID
  130004505551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] VITAMIN B12 SUPPLEMENTATION IMPROVES HYPERHOMOCYSTEINEMIA AND COGNITIVE IMPAIRMENT IN PATIENTS WITH VITAMIN B12 DEFICIENCY.2019
- Author(s)
  Ueno, A., Hamano, T., Enomoto, S., Shirafuji, N., Nagata, M., Yamaguchi, T., Kuriyama, M.
- Organizer
  AAIC2019 Alzhimer's Association of International Conference2019 in Los Angeles.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07909
[Presentation] ALPHA-SYNUCLEIN PHOSPHORYLATION BY HOMOCYSTEINE.2019
- Author(s)
  Enomoto, S., Hamano, T., Jiang, P., Shirafuji, N., Sasaki, H., et al.
- Organizer
  AAIC2019 Alzhimer's Association of International Conference2019 in Los Angeles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07909
[Presentation] Homocysteine Increases Tau Phosphorylation Truncation and Oligomerization.2018
- Author(s)
  Norimichi Shirafuji
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-15K08904
[Presentation] EFFECTIVENESS OF PITAVASTATIN IN PATIENTS WITH MILD ALZHEIMER'S DISEASE AND HYPERLIPIDEMIA2017
- Author(s)
  Hamano, T., Hayashi, K., Ueno, A., Shirafuji, N., Fujita, Y., et al.,
- Organizer
  AAIC 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09235
[Presentation] HYPOPERFUSION-INDUCED TAU HYPERPHOSPHORYLATION EXTENDS TO THE NON-HYPOPERFUSED AREA IN MOUSE BRAIN.2016
- Author(s)
  Fujita, Y., Hamano, T., Shirafuji, N., & Nakamoto, Y. .
- Organizer
  Alzheimer's Association International Conference (AAIC) 2016
- Place of Presentation
  Toronto, Canada
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09235
[Presentation] Efficacy of short questionnaire for screening of early stage of dementia2016
- Author(s)
  Hamano T, Fujita Y, Matsubara R, Nagata M, Ikebata Y, Ito T, Endo Y, Ueno A, Shirafuji N, Hayashi K, Yamamura O, Nakamoto Y
- Organizer
  Alzheimer's Association International Conference AAIC2016
- Place of Presentation
  Toronto, Canada
- Year and Date
  2016-07-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] HYPOPERFUSION-INDUCED TAU HYPERPHOSPHORYLATION EXTENDS TO THE NON-HYPOPERFUSED AREA IN MOUSE BRAIN.2016
- Author(s)
  Fujita,Y.,Hamano,T., Shirafuji,N.
- Organizer
  Alzheimer's Association International Conference (AAIC) 2016
- Place of Presentation
  Tronto, Canada
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08904
[Presentation] Hypoperfusion-Induced tau Hyperphosphorylation Extends to the Non-Hypoperfused Area in Mouse Brain2016
- Author(s)
  Fujita Y, Hamano T, Shirafuji N, Nakamoto Y
- Organizer
  Alzheimer's Association International Conference AAIC2016
- Place of Presentation
  Toronto, Canada
- Year and Date
  2016-07-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] Clioquinol decreases phosphorylation levels of tau protein.2015
- Author(s)
  Lin G, Hamano T, Shirafuji N, Ishida A, Nakamoto Y
- Organizer
  Alzheimer's Association International Conference AAIC2015
- Place of Presentation
  Washington DC, USA
- Year and Date
  2015-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] Reduction of cholineesterase by cholineesterase inhibitor (Donepezil, Galantamine, or Rivaastigmine).2015
- Author(s)
  Hayashi K, Hamano T, SHirafuji N, Nakamoto Y
- Organizer
  Alzheimer's Association International Conference AAIC2015
- Place of Presentation
  Washington DC, USA
- Year and Date
  2015-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] ROCK inhibitor decreases phosphorylation levels of tau protein2014
- Author(s)
  Hamano T, Shirafuji N, Yen SH, Ishida A, Fujita Y, Matsunaga A, Yamamura O, Kuriyama M, Nakamot Y
- Organizer
  Alzheimers Association International Conference 2014
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] Homocysteine accelerates tau aggregation via caspase activation.2013
- Author(s)
  Shirafuji, N., Hamano, T., Ishi-da, A., Yoneda, M., Kuriyama, M., Nakamoto, Y.
- Organizer
  Alzheimers Association International Conference 2013
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] Donepezil reduces phosphorylation levels of tau protein in a cellular model of tauopathy.2013
- Author(s)
  Hamano, T., Shirafuji, N., Sasaki, H., Ishi-da, A., Ueno, A., Yen, S. H., Nakamoto, Y.
- Organizer
  Alzheimers Association International Conference 2013
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] ROCK INHIBITOR DECREASES PHOSPHORYLATION LEVELS OF TAU PROTEIN.
- Author(s)
  Shirafuji, N., Hamano, T., Yen, S. H., Ishida, A., Fujita, Y., Matsunaga, A., ... & Nakamoto, Y.
- Organizer
  Alzheimer Association International Conference AAIC 2014
- Place of Presentation
  Copenhagen (Denmark)
- Year and Date
  2014-07-12 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] CHRONIC CEREBRAL HYPOPERFUSION INDUCES TAU HYPERPHOSPHORYLATION ACCOMPANIED BY AXONAL DAMAGE IN ADULT MICE.
- Author(s)
  Fujita, Y., Hamano, T., Shirafuji, N., & Nakamoto, Y.
- Organizer
  Alzheimer Association International Conference AAIC 2014
- Place of Presentation
  Copenhagen (Denmark)
- Year and Date
  2014-07-12 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] Clioquinol Decreases Phosphorylation Leves of Tau Protein
- Author(s)
  Lin K, Hamano T, Shirafuji N, Ishida A, Nakamoto Y
- Organizer
  Alzheimer Association International Conference AAIC 2015
- Place of Presentation
  Washington DC (USA)
- Year and Date
  2015-07-18 – 2015-07-23
- Data Source
  KAKENHI-PROJECT-25460893
[Presentation] Reduction of Serum Cholinesterase By Cholinesterase Inhibitor (Donepezil, Galantamine, or Rivastigmine)
- Author(s)
  Hayashi K, Hamano T, Shirafuji N, Nakamoto Y
- Organizer
  Alzheimer Association International Conference AAIC 2015
- Place of Presentation
  Washington DC (USA)
- Year and Date
  2015-07-18 – 2015-07-23
- Data Source
  KAKENHI-PROJECT-25460893

1. HAMANO TADANORI (40334817)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. Naiki Hironobu (10227704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 吉田裕孝 (70646570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Fujita Youshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. OKAZWA Hidehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 浜野忠則

# of Collaborated Projects: 0 results

# of Collaborated Products: 36 results
7. 武藤多津郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 鈴木仁弥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 小野賢二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shirafuji Norimichi 白藤 法道

Research Projects

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Co-Researchers

Mechanisms of Tau oligomer formation by autophagy dysfunction.

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Tau oligomerization by BioMetals

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Rho-kinase ROCK Inhibitors Reduce Oligomeric Tau Protein

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Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.Principal Investigator

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Molecular mechanisms of Alzheimer's disease induced by oligomeric tau protein.

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[Journal Article] Effectiveness of a self-reporting yes/no survey for dementia screening-trial in Fukui, Japan.2023

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[Journal Article] Magnetic resonance imaging arterial spin labeling hypoperfusion with diffusion-weighted image hyperintensity is useful for diagnostic imaging of Creutzfeldt-Jakob disease.2023

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[Journal Article] Regional cortical hypoperfusion and atrophy correlate with striatal dopaminergic loss in Parkinson's disease: a study using arterial spin labeling MR perfusion.2023

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[Journal Article] Rho-ROCK阻害薬によるタウ蛋白オリゴマー形成抑制2022

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[Journal Article] Arterial spin labeling imaging for the detection of cerebral blood flow asymmetry in patients with corticobasal syndrome.2022

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[Journal Article] Influences of Vitamin B12 Supplementation on Cognition and Homocysteine in Patients with Vitamin B12 Deficiency and Cognitive Impairment.2022

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[Journal Article] Persistent Severe Cerebral Edema with Neutrophil Infiltration Following<i> Listeria</i> Meningitis2022

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[Journal Article] An exploratory, open-label, randomized, multicenter trial of hachimijiogan for mild Alzheimer’s disease2022

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[Journal Article] タウ蛋白とオートファジー.2021

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NAID

Shirafuji Norimichi 白藤法道

[Journal Article] Rho-ROCK阻害薬によるタウ蛋白オリゴマー形成抑制機構の解明2018