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Arita Kyohei  有田 恭平

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ARITA Kyohei  有田 恭平

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Researcher Number 40549648
Other IDs
Affiliation (Current) 2025: 横浜市立大学, 生命医科学研究科, 教授
Affiliation (based on the past Project Information) *help 2020 – 2025: 横浜市立大学, 生命医科学研究科, 教授
2017 – 2020: 横浜市立大学, 生命医科学研究科, 准教授
2013 – 2014: 横浜市立大学, 生命ナノシステム科学研究科, 准教授
2013 – 2014: 横浜市立大学, 生命医科学研究科, 准教授
2012: 京都大学, 工学(系)研究科(研究院), 助教 … More
2010 – 2011: 京都大学, 工学研究科, 助教
2010: 京都大学, (連合)農学研究科(研究院), 助教
2009: Kyoto University, 農学研究科, 助教 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Structural biochemistry / Basic Section 43020:Structural biochemistry-related / Transformative Research Areas, Section (III) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Complex systems
Except Principal Investigator
Basic Section 43050:Genome biology-related / Biological Sciences / Basic Section 43010:Molecular biology-related / Laboratory animal science / Neurochemistry/Neuropharmacology
Keywords
Principal Investigator
UHRF1 / 構造生物学 / エピジェネティクス / DNA維持メチル化 / ヒストン修飾 / DNAメチル化 / ユビキチン化 / X線結晶構造解析 / クライオ電子顕微鏡 / DNMT1 … More / DNA複製 / クロマチン / 天然変性タンパク質 / リン酸化 / CDCA7 / 片鎖メチル化DNA / DNAメチル化酵素 / 構造生命科学 / 非ゲノム情報 / Cryo-EM / cryo-EM / 非ゲノム情報複製 / DPPA3 / マルチモノユビキチン化 / ユビキチン / 分子動力学計算 / LIG1 / 複製因子 / タンパク質間相互作用 / タンパク質相互作用 / UHRF1タンパク質 / 天然変性 … More
Except Principal Investigator
DNAメチル化 / UHRF1 / ゲノム安定性 / DNA複製 / ヒストン修飾 / ユビキチン / CDCA7 / DNA損傷 / 染色体高次構造 / 複製 / 技術支援 / 若手支援 / 総括班研究 / 非ゲノム情報複製 / ニュースレター / 班会議 / 国際シンポジウム / 総括班 / 非ゲノム情報 / クロマチン / ノンコーディングRNA / エピゲノム情報 / 転写因子 / 非コードRNA / エピゲノム / DNMT1 / ラギング鎖 / LIG3 / HPF1 / PARP1 / ヒストン / LIG1 / ADPリボシル化 / 岡崎フラグメント / リプログラミング / 配偶子形成 / 卵子形成 / 卵子 / エピジェネティクス / 生殖細胞 / 着床前発生 / 初期発生 / 卵母細胞 / 線虫 / フィラミン / Filamin / リン酸化 / Filamin-A / CRMP1 / Sema3A / セマフォリン / アクチン / 細胞骨格 / 神経回路形成 Less
  • Research Projects

    (16 results)
  • Research Products

    (105 results)
  • Co-Researchers

    (25 People)
  •  機動性DNAエレメントの発動・抑制の構造基盤とその制御技術の開発Principal Investigator

    • Principal Investigator
      有田 恭平
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Yokohama City University
  •  DNAメチル化酵素の包括的な理解に向けた構造生命科学研究とその応用Principal Investigator

    • Principal Investigator
      有田 恭平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Yokohama City University
  •  Molecular mechanism of DNA replication-uncoupled maintenance DNA methylation

    • Principal Investigator
      西山 敦哉
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43050:Genome biology-related
    • Research Institution
      The University of Tokyo
  •  片鎖メチル化DNAの新たな細胞機能の解明を目指した検出ツールの開発Principal Investigator

    • Principal Investigator
      有田 恭平
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Yokohama City University
  •  UHRF1によるマルチモノユビキチン化反応の構造基盤Principal Investigator

    • Principal Investigator
      有田 恭平
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Yokohama City University
  •  Molecular Mechanisms for Regulation of Genomic Stability via DNA Methylation

    • Principal Investigator
      Nishiyama Atsuya
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      The University of Tokyo
  •  Structural basis for establishment and maintenance of DNA methylation and histone H3K9me3Principal Investigator

    • Principal Investigator
      Arita Kyohei
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  Mechanisms underlying replication of non-genomic codes that mediate plasticity and robustness for cellular inheritance

    • Principal Investigator
      Nakanishi Makoto
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Structural basis for DNA methylation maintenance regulated by replication factors.Principal Investigator

    • Principal Investigator
      Arita Kyohei
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Yokohama City University
  •  Role of UHRF1 during oogenesis and early embryogenesis

    • Principal Investigator
      UNOKI Motoko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kyushu University
  •  維持メチル化におけるUHRF1の高次構造の形成と変換機構の構造基盤およびその応用Principal Investigator

    • Principal Investigator
      有田 恭平
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      Yokohama City University
  •  UHRF1タンパク質の天然変性領域の機能-構造解析Principal Investigator

    • Principal Investigator
      有田 恭平
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
      Kyoto University
  •  Interaction of CRMP1 and Filamin-A regulates F-actin-cytoskeleton.

    • Principal Investigator
      NAKAMURA Fumio
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Yokohama City University
  •  UHRF1タンパク質のリン酸化制御による構造機能変換機構の解明Principal Investigator

    • Principal Investigator
      有田 恭平
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Structural basis for the epigenetic regulation by UHRF1 interacting proteins.研究代表者有田恭平(Kyohei Arita)Principal Investigator

    • Principal Investigator
      ARITA Kyohei
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University
  •  エピジェネティクスに関与する生体超分子の構造生物学的研究Principal Investigator

    • Principal Investigator
      有田 恭平
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2014 2013 2012 2011 2010 2009

All Journal Article Presentation Book

  • [Book] Cytosine Methylation to Histone Modification in Arabidopsis thaliana2011

    • Author(s)
      Arita K., Kanno T., Yoshikawa M., Habu Y.
    • Total Pages
      13
    • Publisher
      Non coding RNA in plants (Springer出版)
    • Data Source
      KAKENHI-PUBLICLY-22113511
  • [Book] Non coding RNA in plants2011

    • Author(s)
      Arita K., Kanno T., Yoshikawa M., and Habu Y.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Book] Cytosine Methylation to Histone Modification in Arabidopsis thaliana2011

    • Author(s)
      Arita K., Kanno T., Yoshikawa M., Habu Y
    • Total Pages
      13
    • Publisher
      Non coding RNA in plants (Springer出版)
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Journal Article] Cryo-electron microscopy reveals the impact of the nucleosome dynamics on transcription activity2024

    • Author(s)
      Arita Kyohei
    • Journal Title

      The Journal of Biochemistry

      Volume: 175 Issue: 4 Pages: 383-385

    • DOI

      10.1093/jb/mvae004

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Journal Article] The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD52023

    • Author(s)
      Miyashita Ryota、Nishiyama Atsuya、Qin Weihua、Chiba Yoshie、Kori Satomi、Kato Norie、Konishi Chieko、Kumamoto Soichiro、Kozuka-Hata Hiroko、Oyama Masaaki、Kawasoe Yoshitaka、Tsurimoto Toshiki、Takahashi Tatsuro S、Leonhardt Heinrich、Arita Kyohei、Nakanishi Makoto
    • Journal Title

      eLife

      Volume: 12 Pages: 79013-79013

    • DOI

      10.7554/elife.79013

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15036, KAKENHI-PLANNED-21H05280, KAKENHI-PROJECT-19H03153, KAKENHI-PROJECT-20H03186, KAKENHI-ORGANIZER-19H05739, KAKENHI-PUBLICLY-21H00272, KAKENHI-PUBLICLY-22H04697
  • [Journal Article] Cooperative DNA-binding activities of Chp2 are critical for its function in heterochromatin assembly2023

    • Author(s)
      Rahayu Anisa Fitri、Hayashi Aki、Yoshimura Yuriko、Nakagawa Reiko、Arita Kyohei、Nakayama Jun-ichi
    • Journal Title

      The Journal of Biochemistry

      Volume: 174 Issue: 4 Pages: 371-382

    • DOI

      10.1093/jb/mvad050

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Journal Article] Structural basis for activation of DNMT12022

    • Author(s)
      Kikuchi A, Onoda H, Yamaguchi K, Kori S, Matsuzawa S, Chiba Y, Tanimoto S, Yoshimi S, Sato H, Yamagata A, Shirouzu M, Adachi N, Sharif J, Koseki H, Nishiyama A, Nakanishi M, Defossez PA, Arita K
    • Journal Title

      Nat Commun.

      Volume: 13 (1) Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41467-022-34779-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06129, KAKENHI-PUBLICLY-21H05733, KAKENHI-PROJECT-19H03153, KAKENHI-ORGANIZER-19H05739, KAKENHI-PUBLICLY-21H00272, KAKENHI-PROJECT-23K23828, KAKENHI-PLANNED-19H05741
  • [Journal Article] Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger.2022

    • Author(s)
      Hata K, Kobayashi N, Sugimura K, Qin W, Haxholli D, Chiba Y, Yoshimi S, Hayashi G, Onoda H, Ikegami T, Mulholland CB, Nishiyama A, Nakanishi M, Leonhardt H, Konuma T, Arita K
    • Journal Title

      Nucleic Acids Res.

      Volume: 50 Issue: 21 Pages: 12527-12542

    • DOI

      10.1093/nar/gkac1082

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06509, KAKENHI-PROJECT-19H03153, KAKENHI-ORGANIZER-19H05739, KAKENHI-PUBLICLY-21H00272, KAKENHI-PLANNED-19H05741
  • [Journal Article] Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza2021

    • Author(s)
      Ohno Ayako、Maita Nobuo、Tabata Takanori、Nagano Hikaru、Arita Kyohei、Ariyoshi Mariko、Uchida Takayuki、Nakao Reiko、Ulla Anayt、Sugiura Kosuke、Kishimoto Koji、Teshima-Kondo Shigetada、Okumura Yuushi、Nikawa Takeshi
    • Journal Title

      Life Science Alliance

      Volume: 4 Issue: 6 Pages: e202000849-e202000849

    • DOI

      10.26508/lsa.202000849

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05739, KAKENHI-PROJECT-19H04054, KAKENHI-PROJECT-18K08453, KAKENHI-PROJECT-18K10994, KAKENHI-PLANNED-19H05741, KAKENHI-PROJECT-19K05696
  • [Journal Article] Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF12021

    • Author(s)
      Kori Satomi、Shibahashi Yuki、Ekimoto Toru、Nishiyama Atsuya、Yoshimi Sae、Yamaguchi Kosuke、Nagatoishi Satoru、Ohta Masateru、Tsumoto Kouhei、Nakanishi Makoto、Defossez Pierre-Antoine、Ikeguchi Mitsunori、Arita Kyohei
    • Journal Title

      Bioorg Med Chem

      Volume: 52 Pages: 116500-116500

    • DOI

      10.1016/j.bmc.2021.116500

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-18H05425, KAKENHI-PLANNED-18H05426, KAKENHI-PUBLICLY-21H00272, KAKENHI-PROJECT-19H03153, KAKENHI-PROJECT-19J22030, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05741
  • [Journal Article] Preparation of the ubiquitination-triggered active form of SETDB1 in Escherichia coli for biochemical and structural analyses2021

    • Author(s)
      Funyu Tomoko、Kanemaru Yuka、Onoda Hiroki、Arita Kyohei
    • Journal Title

      The Journal of Biochemistry

      Volume: 170 Issue: 5 Pages: 655-662

    • DOI

      10.1093/jb/mvab087

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05741
  • [Journal Article] Serine 298 Phosphorylation in Linker 2 of UHRF1 Regulates Ligand-Binding Property of Its Tandem Tudor Domain2020

    • Author(s)
      Kori Satomi、Jimenji Tomohiro、Ekimoto Toru、Sato Miwa、Kusano Fumie、Oda Takashi、Unoki Motoko、Ikeguchi Mitsunori、Arita Kyohei
    • Journal Title

      Journal of Molecular Biology

      Volume: 432 Issue: 14 Pages: 4061-4075

    • DOI

      10.1016/j.jmb.2020.05.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06527, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05741, KAKENHI-PROJECT-18H02391, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-19J22030
  • [Journal Article] Structural dynamics of double-stranded DNA with epigenome modification2020

    • Author(s)
      Furukawa Ayako、Walinda Erik、Arita Kyohei、Sugase Kenji
    • Journal Title

      Nucleic Acids Research

      Volume: 49 Issue: 2 Pages: 1152-1162

    • DOI

      10.1093/nar/gkaa1210

    • NAID

      120006943328

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05741, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-18K14665
  • [Journal Article] Enhanced processivity of Dnmt1 by monoubiquitinated histone H32020

    • Author(s)
      Y. Mishima, L. Brueckner, S. Takahashi, T. Kawakami, J. Otani, A. Shinohara, K. Takeshita, R. G. Garvilles, M. Watanabe, N. Sakai, H. Takeshima, C. Nachtegael, A. Nishiyama, M. Nakanishi, K. Arita, K. Nakashima, H. Hojo, I. Suetake
    • Journal Title

      Genes Cells

      Volume: 25 Issue: 1 Pages: 22-32

    • DOI

      10.1111/gtc.12732

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05316, KAKENHI-PROJECT-18K06095, KAKENHI-PROJECT-18K14681, KAKENHI-PROJECT-19K17878, KAKENHI-PLANNED-15H05973, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-19H04048, KAKENHI-PROJECT-18K15211, KAKENHI-PLANNED-19H05740, KAKENHI-PLANNED-19H05741, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-19H00981, KAKENHI-ORGANIZER-19H05739
  • [Journal Article] Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation2020

    • Author(s)
      A. Nishiyama, C. Mulholland, S. Bultmann, S. Kori, A. Endo, Y. Saeki, W. Qin, C. Trummer, Y. Chiba, H. Yokoyama, S. Kumamoto, T. Kawakami, H. Hojo, G. Nagae, H. Aburatani, K. Tanaka, K. Arita, H. Leonhardt, M. Nakanishi
    • Journal Title

      Nat. Commun.

      Volume: 11 Issue: 1 Pages: 1222-1222

    • DOI

      10.1038/s41467-020-15006-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05316, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PUBLICLY-19H05285, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-19H03153, KAKENHI-PROJECT-19J22030, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18K07963, KAKENHI-ORGANIZER-19H05739
  • [Journal Article] Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation2019

    • Author(s)
      Kori, S. Ferry, L. Matano, S. Jimenji, T. Kodera, N. Tsusaka, T. Matsumura, R. Oda, T. Sato, M. Dohmae, N. Ando, T. Shinkai, Y. Defossez, P. A. Arita, K.
    • Journal Title

      Structure

      Volume: 27 Issue: 3 Pages: 1-12

    • DOI

      10.1016/j.str.2018.11.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19345, KAKENHI-PLANNED-18H05530, KAKENHI-PLANNED-26119003, KAKENHI-PROJECT-18H02391, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-18H03991
  • [Journal Article] Structure of PCNA in complex with DNMT1 PIP box reveals the basis for the molecular mechanism of the interaction.2019

    • Author(s)
      1.Jimenji T, Matsumura R, Kori S, Arita K.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 516 Issue: 2 Pages: 578-583

    • DOI

      10.1016/j.bbrc.2019.06.060

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H05294, KAKENHI-PROJECT-18H02392, KAKENHI-PLANNED-19H05741
  • [Journal Article] The structural basis for receptor recognition of human interleukin-182014

    • Author(s)
      Naotaka Tsutsumi, Takeshi Kimura, Kyohei Arita, Mariko Ariyoshi, Hidenori Ohnishi, Takahiro Yamamoto, Xiaobing Zuo, Katsumi Maenaka, Enoch Y. Park, Naomi Kondo, Masahiro Shirakawa, Hidehito Tochio and Zenichiro Kato
    • Journal Title

      Nat. Commun.

      Volume: 5 5340 Issue: 1 Pages: 1-13

    • DOI

      10.1038/ncomms6340

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J02660, KAKENHI-PLANNED-22121007, KAKENHI-PUBLICLY-25112514, KAKENHI-PROJECT-25461588, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-26461576, KAKENHI-PROJECT-26711004
  • [Journal Article] Purification, crystallization and preliminary X-ray crystallographic analysis of human IL-18 and its extracellular complexes2014

    • Author(s)
      Takeshi Kimura, Naotaka Tsutsumi, Kyohei Arita, Mariko Ariyoshi, Hidenori Ohnishi, Naomi Kondo, Masahiro Shirakawa, Zenichiro Kato and Hidehito Tochio
    • Journal Title

      Acta Crystallogr. Sect. F Struct. Biol. Commun.

      Volume: 70 Issue: 10 Pages: 1351-1356

    • DOI

      10.1107/s2053230x14016926

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J02660, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-26461576, KAKENHI-PROJECT-26711004
  • [Journal Article] The DNA methyltransferase Dnmt1 directly interacts with the SET and RING finger-associated (SRA) domain of the multifunctional protein Uhrf1 to facilitate accession of the catalytic center to hemi-methylated DNA2014

    • Author(s)
      Berkyurek AC, Suetake I, Arita K, Takeshita K, Nakagawa A, Shirakawa M, Tajima S
    • Journal Title

      J Biol Chem

      Volume: 289(1) Issue: 1 Pages: 379-86

    • DOI

      10.1074/jbc.m113.523209

    • NAID

      120006770872

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23770145, KAKENHI-PUBLICLY-24113711, KAKENHI-PUBLICLY-24116515, KAKENHI-PROJECT-24570153, KAKENHI-PROJECT-24651214, KAKENHI-PROJECT-25291025
  • [Journal Article] Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4.2013

    • Author(s)
      Otani, J., Arita, K., Kato, T., Kinoshita, M., Kimura, H., Suetake, I., Tajima, S., Ariyoshi, M., Shirakawa, M.
    • Journal Title

      J Biol. Chem.

      Volume: 288 Issue: 9 Pages: 6351-6362

    • DOI

      10.1074/jbc.m112.431098

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121006, KAKENHI-PROJECT-22370053, KAKENHI-PROJECT-24570153, KAKENHI-PROJECT-25650007, KAKENHI-PLANNED-23114005, KAKENHI-PUBLICLY-24113711, KAKENHI-PUBLICLY-24116515
  • [Journal Article] Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication2013

    • Author(s)
      Nishiyama, A
    • Journal Title

      Nature

      Volume: 502 Issue: 7470 Pages: 249-253

    • DOI

      10.1038/nature12488

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118003, KAKENHI-PROJECT-23240124, KAKENHI-PROJECT-23249015, KAKENHI-PUBLICLY-24113711, KAKENHI-PROJECT-24659137, KAKENHI-PROJECT-24790290, KAKENHI-PUBLICLY-25131717, KAKENHI-PROJECT-25461659
  • [Journal Article] Development of Fluorogenic Probes for Quick No-Wash Live-Cell Imaging of Intracellular Proteins2013

    • Author(s)
      Y. Hori, T. Norinobu, M. Sato, K. Arita, S. Shirakawa & K. Kikuchi
    • Journal Title

      J. Am. Chem. Soc

      Volume: 135 Issue: 33 Pages: 12360-12365

    • DOI

      10.1021/ja405745v

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20675004, KAKENHI-PLANNED-21121006, KAKENHI-PROJECT-22685016, KAKENHI-PUBLICLY-24108724, KAKENHI-PUBLICLY-24113711
  • [Journal Article] Lysyl 5-Hydroxylation, a Novel Histone Modification, by Jumonji Domain Containing 6 (JMJD6)2013

    • Author(s)
      M. Unoki, A. Masuda, N. Dohmae, K. Arita, M. Yoshimatsu, Y. Iwai, Y. Fukui, K. Ueda, R. Hamamoto, M. Shirakawa, H. Sasaki, and Y. Nakamura
    • Journal Title

      The Journal of biological chemistry

      Volume: 288(9) Issue: 9 Pages: 6053-62

    • DOI

      10.1074/jbc.m112.433284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22680064, KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-24113711
  • [Journal Article] Quantitative comparison of protein dynamics in live cells and in vitro by in-cell (19)F-NMR.2013

    • Author(s)
      Takaoka Y, Kioi Y, Morito A, Otani J, Arita K, Ashihara E, Ariyoshi M, Tochio H, Shirakawa M, Hamachi I.
    • Journal Title

      Chem Commun

      Volume: 49 Issue: 27 Pages: 2801-2803

    • DOI

      10.1039/c3cc39205h

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21121006, KAKENHI-PLANNED-23115004, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23750188, KAKENHI-PUBLICLY-24113711, KAKENHI-PLANNED-21121005, KAKENHI-PUBLICLY-24102516
  • [Journal Article] Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF12012

    • Author(s)
      K.Arita, S.Isogai, T.Oda, M.Unoki, K.Sugita, N.Sekiyama, K.Kuwata, R.Hamamoto, H.Tochio, M.Sato, M.Ariyoshi, and M.Shirakawa
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109 Issue: 32 Pages: 12950-12955

    • DOI

      10.1073/pnas.1203701109

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21113001, KAKENHI-PLANNED-21113002, KAKENHI-PLANNED-21121006, KAKENHI-PROJECT-22370038, KAKENHI-PLANNED-23114005, KAKENHI-PUBLICLY-24113711
  • [Journal Article] Crystal structure of the ubiquitin-associated(UBA) domain of p62 and its interaction with ubiquitin2011

    • Author(s)
      Isogai S, Morimoto D, Arita K, Unzai S, Tenno T, Hasegawa J, Sou YS, Komatsu M, Tanaka K, Shirakawa M, Tochio H
    • Journal Title

      Journal of Biochemistry

      Volume: 286 Pages: 31864-3187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Journal Article] Crystal structure of the UBA domain of p62 and its interaction with ubiquitin2011

    • Author(s)
      Isogai, S., Morimoto, D., Arita, K., Unzai, S., Tenno, T., Hasegawa, J., Sou, Y.S., Komatsu, M., Tanaka, K., Shirakawa, M., Tochio, H.
    • Journal Title

      J Biol Chem.

      Volume: 286 Issue: 36 Pages: 31864-318674

    • DOI

      10.1074/jbc.m111.259630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000012, KAKENHI-PLANNED-21121006, KAKENHI-PROJECT-21247013, KAKENHI-PUBLICLY-22113511, KAKENHI-PROJECT-22370038, KAKENHI-PROJECT-22687008, KAKENHI-PLANNED-23115004, KAKENHI-PROJECT-23570145, KAKENHI-PROJECT-23659586
  • [Journal Article] Structural basis for recognition of poly-SUMO chain by a SUMO-like domain of Nip452010

    • Author(s)
      Sekiyama N, Arita K, Ikeda Y, Hashiguchi K, Ariyoshi M, Tochio H, Saitoh H, Shirakawa M
    • Journal Title

      Proteins

      Volume: 78 Pages: 1491-1502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Journal Article] Structural basis for recognition of poly-SUMO chain by a SUMO-like domain of Nip45.2010

    • Author(s)
      Sekiyama N, Arita K, Ikeda Y, Hashiguchi K, Ariyoshi M, Tochio H, Saitoh H, Shirakawa M.
    • Journal Title

      Proteins

      Volume: 78 Pages: 1491-1502

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22113511
  • [Journal Article] Structural basis for recognition of H3K4 methylation status by the DNMT3A ADD domain2009

    • Author(s)
      Otani J., Nankumo T., Arita K., Inamoto S., Ariyoshi M., Shirakawa M.
    • Journal Title

      Embo report 11

      Pages: 1235-1241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21870015
  • [Journal Article] tructural basis fir regulation of poky-SIMO chain by SUMO-like domain of Nip452009

    • Author(s)
      Sekiyama N., Arita K., Ikeda Y., Hashiguchi K., Ariyoshi M., Tochio H., Saitoh H., Shirakawa M.
    • Journal Title

      Proteins 6

      Pages: 1491-1502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21870015
  • [Presentation] Structural basis for activation mechanism of DNMT12023

    • Author(s)
      Kyohei Arita
    • Organizer
      The 2nd International Symposium on REPLICATION of NON GENOME
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] USP7とATAD5はUHRF1依存的なPAF15ユビキチンシグナルを制御する2022

    • Author(s)
      西山 敦哉 宮下 諒太 千葉 祥恵 郡 聡実 加藤 修衣 河添 好孝 秦 裕子 尾山 大明 高橋 達郎 有田 恭平 中西 真
    • Organizer
      第45回分子生物学会年会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03153
  • [Presentation] 大腸菌内ユビキチン化システムによる活性型 SETDB1 の調製と評価2022

    • Author(s)
      舩生 智子、小野田 浩宜、山形 敦史、有田 恭平
    • Organizer
      第22回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] USP7によるユビキチン化ヒストンH3の脱ユビキチン化機構の解明2022

    • Author(s)
      吉見 早恵 小野田 浩宜 加藤 修衣 山形 敦史 有田 恭平
    • Organizer
      第45回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] DNMT1:ユビキチン化H3:DNA複合体構造によるDNA維持メチル化の活性化機構の解明2022

    • Author(s)
      菊地杏美香, 小野田浩宜, 山口幸佑, 郡聡実, 山形敦史, Defossez Pierre-Antoine, 有田恭平
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] グアニン四重鎖によるDNMT1の活性阻害機構の解明2022

    • Author(s)
      菊地杏美香, 小野田浩宜, 山形敦史, 有田恭平
    • Organizer
      第15回 日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Structural basis for activation of DNA methyltransferase.2022

    • Author(s)
      有田恭平
    • Organizer
      第15回日本エピジェネティクス研究会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] DNA維持メチル化関連タンパク質の活性・クロマチン局在制御の構造基盤2022

    • Author(s)
      有田恭平
    • Organizer
      第45回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] UHRF1によるマルチモノユビキチン化機構の構造生物学的研究2022

    • Author(s)
      蛭田 萌理, 松澤 舜, 敷町 怜愛, 有田 恭平
    • Organizer
      第45回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] ユビキチン化によるSETDB1の酵素活性化機構の解明2022

    • Author(s)
      舩生 智子、山形 敦史、有田 恭平
    • Organizer
      第45回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] エピジェネティック修飾ヌクレオソームに対するUHRF1の相互作用様式の検証2022

    • Author(s)
      敷町 怜愛, 松澤 舜, 蛭田萌里, 小野田 浩宜, 山形敦史, 有田 恭平
    • Organizer
      第45回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] DPPA3によるUHRF1のクロマチン局在阻害の構造基盤2022

    • Author(s)
      有田恭平
    • Organizer
      第95回日本生化学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] 構造生物学から見たDNAメチル化が複製されていく仕組み2021

    • Author(s)
      有田 恭平
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05739
  • [Presentation] 計算科学と構造生物学を組み合わせたスクリーニングによるDNAメチル化制御薬の開発2021

    • Author(s)
      郡聡実, 柴橋佑希, 浴本亨, 西山敦哉, 吉見早恵, 長門石暁, 大田雅照, 津本浩平, 中西真, 池口満徳, 有田恭平
    • Organizer
      第12回スクリーニング学研究会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] 構造生物学から見たDNAメチル化が複製されていく仕組み2021

    • Author(s)
      有田恭平
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Development of UHRF1 inhibitor based on the structural study of the recognition of methylated DNA ligase 1 by UHRF12021

    • Author(s)
      Satomi Kori, Yuki Shibahashi, Toru Ekimoto, Atsuya Nishiyama, Sae Yoshimi, Satoru Nagatoishi, Masateru Ohta, Kouhei Tsumoto, Mitsunori Ikeguchi, and Kyohei Arita
    • Organizer
      PDBアジア地区50周年記念シンポジウム
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] マルチモノユビキチン化機構の解明に向けたエピジェネティック修飾ヌクレオソームの調製2021

    • Author(s)
      敷町怜愛, 松澤舜, 小野田浩宜, 有田恭平
    • Organizer
      第44回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] USP7によるユビキチン化ヒストンH3の脱ユビキチン化機構の解明2021

    • Author(s)
      吉見早恵, 小野田浩宜, 山形敦史, 有田恭平
    • Organizer
      第44回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] DNAメチル化を制御する薬剤の開発:構造生物学と計算科学を組み合わせた維持メチル化因子UHRF1の機能阻害剤の探索2021

    • Author(s)
      郡聡実, 柴橋佑希, 浴本亨, 西山敦哉, 吉見早恵 ,長門石暁, 大田雅照, 津本浩平, 中西真, 池口満徳, 有田恭平
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] ユビキチン化依存的なSETDB1の酵素活性化機構解明に向けた、大腸菌内ユビキチン化システムの構築とその評価2021

    • Author(s)
      舩生智子, 金丸由桂, 有田恭平
    • Organizer
      第44回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] The proper timing phosphorylation of Ser298 selects UHRF1-binding partners2021

    • Author(s)
      Satomi Kori, Tomohiro Jimenji, Toru Ekimoto, Laure Ferry, Shohei Matano, Miwa Sato, Fumie Kusano, Motoko Unoki, Pierre-Antoine Defossez, Mitsunori Ikeguchi, Kyohei Arita
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] 構造生物学から見たDNAメチル化が複製されていく仕組み2021

    • Author(s)
      有田恭平
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] DNAメチル化制御薬の開発:維持メチル化因子UHRF1の機能阻害剤のリード化合物の同定2021

    • Author(s)
      郡聡実, 柴橋佑希, 浴本亨, 西山敦哉, 吉見早恵, 長門石暁, 大田雅照, 津本浩平, 中西真, 池口満徳, 有田恭平
    • Organizer
      第49回構造活性相関シンポジウム
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] 母性因子Stellaと維持メチル化因子UHRF1のNMRを用いた相互作用解析2021

    • Author(s)
      畑圭一, 小沼剛, 杉村奎汰, 西山敦哉, 林剛介, 池上貴久, 中西真, 有田恭平
    • Organizer
      第44回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] G-quadruplex構造によるDNMT1の活性阻害機構の解明2021

    • Author(s)
      菊地杏美香, 小野田浩宜, 山形敦史, 有田恭平
    • Organizer
      第44回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Structural basis for the switching of binding partners by Ser298 phosphorylation in UHRF12020

    • Author(s)
      Satomi Kori, Tomohiro Jimenji, Toru Ekimoto, Miwa Sato, Fumie Kusano, Takashi Oda, Motoko Unoki, Mitsunori Ikeguchi, Kyohei Arita
    • Organizer
      第20回蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Structural basis for the switching of binding partners by Ser298 phosphorylation in UHRF12020

    • Author(s)
      Satomi Kori, Tomohiro Jimenji, Toru Ekimoto, Miwa Sato, Fumie Kusano, Takashi Oda, Motoko Unoki, Mitsunori Ikeguchi, Kyohei Arita
    • Organizer
      第20回蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] The proper timing phosphorylation of Ser298 selects UHRF1-binding partners2020

    • Author(s)
      Satomi Kori, Tomohiro Jimenji, Toru Ekimoto, Laure Ferry, Shohei Matano, Miwa Sato, Fumie Kusano, Motoko Unoki, Pierre-Antoine Defossez, Mitsunori Ikeguchi, Kyohei Arita
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Crystal structure of UHRF1:LIG1 complex revealed structural change of UHRF1 and the key residues for high affinity binding2019

    • Author(s)
      Satomi Kori, Laure Ferry, Shohei Matano, Noriyuki Kodera, Takashi Oda, Pierre-Antoine Defossez,Kyohei Arita
    • Organizer
      ECM32 32nd European Crystallographic Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] Structural basis for recognition of DNMT1 PIP box by PCNA2019

    • Author(s)
      Tomohiro Jimenji, Satomi Kori, Kyohei Arita
    • Organizer
      16th Conference of the Asian Crystallographic Association: AsCA2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Crystal structure of UHRF1:LIG1 complex revealed structural change of UHRF1 and the key residues for high affinity binding2019

    • Author(s)
      Satomi Kori, Laure Ferry, Shohei Matano, Noriyuki Kodera, Takashi Oda, Pierre-Antoine Defossez,Kyohei Arita
    • Organizer
      ECM32 32nd European Crystallographic Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Structural Study for Recognition of Ubiquitylated Histone H3 by DNA Methyltransferase2019

    • Author(s)
      Arita Kyohei, Ishiyama Satoshi, Nishiyama, Atsuya, Defossez, Pierre-Antoine, Nakanishi, Makoto
    • Organizer
      ECM32 32nd European Crystallographic Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] UHRF1によるヒストンH3のマルチプルモノユビキチン化機構2019

    • Author(s)
      松澤舜, 若月誠, 柴野歩実, 郡聡実, 古川亜矢子, 西村善文, 西山敦哉, 中西真, 有田恭平
    • Organizer
      第42回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Conserved phosphorylation in UHRF1-binding partners regulates its binding to the peptide binding groove of UHRF1 TTD domain2019

    • Author(s)
      Satomi Kori, Laure Ferry, Shohei Matano, Tomohiro Jimenji, Toru Ekimoti, Takashi Oda, Pierre-Antoine Defossez, Mitsunori Ikeguchi, Kyohei Arita
    • Organizer
      16th Conference of the Asian Crystallographic Association: AsCA2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] Structural basis for recognition of DNMT1 PIP box by PCNA2019

    • Author(s)
      Tomohiro Jimenji, Satomi Kori, Kyohei Arita
    • Organizer
      16th Conference of the Asian Crystallographic Association: AsCA2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] A unique mechanism for multi-monoubiquitination of histone H3 by UHRF12019

    • Author(s)
      松澤舜, 若月誠, 柴野歩実, 郡聡実, 古川亜矢子, 西村善文, 西山敦哉, 中西真, 有田恭平
    • Organizer
      第42回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] 複製因子PAF15のマルチプルモノユビキチン化シグナル形成機構2019

    • Author(s)
      柴野歩実, 松澤舜, 郡聡実, 西山敦哉, 中西真, 有田恭平
    • Organizer
      第42回分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05741
  • [Presentation] DNMT1のメチル化部位への局在を保証する2つの異なる分子機構2019

    • Author(s)
      西山 敦哉, Christopher B. Mulholland, Sebastian Bultmann, 郡 聡実, 遠藤 彬則, 千葉 祥恵, 隈本 宗一郎, 佐伯 泰, 有田 恭平, Heinrich Leonhardt, 中西 真
    • Organizer
      42nd MBSJ, Symposium ” Crosstalk between epigenome replication, genome stability, and chromatin organization ”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03153
  • [Presentation] Molecular mechanism for multiple-monoubiquitination of histone H32019

    • Author(s)
      松澤舜, 柴野歩実, 若月誠, 郡聡実, 有田恭平
    • Organizer
      第13回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PUBLICLY-19H05294
  • [Presentation] Molecular mechanism for multiple-monoubiquitination of replication factor PAF152019

    • Author(s)
      柴野歩実, 松澤舜, 郡聡実, 西山敦哉, 中西真, 有田恭平
    • Organizer
      第42回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] Structural basis for the regulation of DNA methylation maintenance by replication factors2019

    • Author(s)
      郡聡実, 治面地智宏, 又野翔平, 松村るみゑ, 横山遥、西山敦哉、中西真、佐藤衛, Pierre Defossez, 有田恭平
    • Organizer
      第13 回エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] CRYSTAL STRUCTURE OF UHRF1:LIG1 COMPLEX REVEALED STRUCTURAL CHANGE OF UHRF1 AND THE KEY RESIDUES FOR HIGH AFFINITY BINDING2019

    • Author(s)
      Kori Satomi, Ferry Laure, Matano Shohei, Kodera Noriyuki, Oda Takashi, Defossez Pierre-Antoine, Arita Kyohei
    • Organizer
      32nd European Crystallographic Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H05294
  • [Presentation] STRUCTURAL STUDY FOR RECOGNITION OF UBIQUITYLATED HISTONE H3 BY DNA METHYLTRANSFERASE2019

    • Author(s)
      Arita Kyohei, Ishiyama Satoshi, Nishiyama, Atsuya, Defossez, Pierre-Antoine, Nakanishi, Makoto
    • Organizer
      32nd European Crystallographic Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H05294
  • [Presentation] Molecular mechanism for multiple-monoubiquitination of histone H32019

    • Author(s)
      松澤舜, 柴野歩実, 若月誠, 郡聡実, 有田恭平
    • Organizer
      第13 回エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] Structural Study for Recognition of Ubiquitylated Histone H3 by DNA Methyltransferase2019

    • Author(s)
      Arita Kyohei, Ishiyama Satoshi, Nishiyama, Atsuya, Defossez, Pierre-Antoine, Nakanishi, Makoto
    • Organizer
      ECM32 32nd European Crystallographic Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] Conserved phosphorylation in UHRF1-binding partners regulates its binding to the peptide binding groove of UHRF1 TTD domain2019

    • Author(s)
      Satomi Kori, Laure Ferry, Shohei Matano, Tomohiro Jimenji, Toru Ekimoti, Takashi Oda, Pierre-Antoine Defossez, Mitsunori Ikeguchi, Kyohei Arita
    • Organizer
      16th Conference of the Asian Crystallographic Association: AsCA2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] 複製因子DNA ligase 1の認識に基づいたUHRF1の構造変化の解析2018

    • Author(s)
      郡聡実, Laure Ferry, 治面地智宏, 又野翔平, 松村るみゑ, 古寺哲幸, 安藤敏夫, 佐藤衛, Pierre Defossez, 有田恭平
    • Organizer
      第18 回蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] マルチプルモノユビキチン化ヒストンH3が制御するDNA維持メチル化の構造基盤2018

    • Author(s)
      有田恭平, 石山怜, 西山敦哉, 中西真, 川上徹, 末武勲
    • Organizer
      第91 日本生化学化大会
    • Data Source
      KAKENHI-PROJECT-18H02392
  • [Presentation] DNA維持メチル化に関与するUHRF1タンパク質の構造生物学的研究2014

    • Author(s)
      有田恭平, 村上晃満, 草野史衣, 西山敦哉, 中西真, 有吉眞理子, 白川昌宏
    • Organizer
      第87回日本生化学会大会 シンポジウム
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2014-10-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-26711004
  • [Presentation] UHRF1タンパク質によりDNA維持メチル化機構の分子基盤2014

    • Author(s)
      有田恭平, 村上晃満, 草野史衣, 西山敦哉, 中西真, 有吉眞理子, 白川昌宏
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      ワークピア横浜
    • Year and Date
      2014-06-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26711004
  • [Presentation] 維持メチル化におけるUHRF1によるエピジェネティックマークの認識機構の構造2014

    • Author(s)
      有田恭平, 村上晃満, 草野史衣, 西山敦哉, 有吉眞理子, 中西真, 白川昌宏
    • Organizer
      第8回日本エピジェネティクス研究会年会 ポスター
    • Place of Presentation
      伊藤国際学術研究センター
    • Year and Date
      2014-05-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26711004
  • [Presentation] Structure study of UHRF1, recoginition of epigenetic marks2014

    • Author(s)
      K. Arita, M. Ariyoshi, K. Sugita, H. Tochio, M. Shirakawa
    • Organizer
      The 23rd international Union of Crystallography (IUCr) Congress ポスター
    • Place of Presentation
      カナダ モントリオール
    • Year and Date
      2014-08-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26711004
  • [Presentation] Molecular Mechanism of Methylated DNA Recognition by SRA Domain of UHRF22012

    • Author(s)
      Terumitsu Murakami, Kyohei Arita , Mariko Ariyoshi , Hidehito Tochio , Masahiro Shirakawa
    • Organizer
      第35回分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PUBLICLY-24113711
  • [Presentation] Structural basis for recognition of histone modifications by UHRF12011

    • Author(s)
      有田恭平
    • Organizer
      構造エピゲノム研究会第3回ワークショップ
    • Place of Presentation
      理研横浜研究所交流棟ホール
    • Year and Date
      2011-04-25
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] Structural basis for recognition of epigenetic marks by UHRF12011

    • Author(s)
      Kyohei Arita, Kazya Sugita、Motoko Unoki、Ryuji Hamamoto、Shin Isogai、Mariko Ariyoshi、Hidehito Tochio、Masahiro Shirakawa.
    • Organizer
      第11回日本蛋白質科学会年会
    • Year and Date
      2011-06-07
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] Structural basis for recognition of epigenetic modifications by UHRF12011

    • Author(s)
      Kyohei Arita
    • Organizer
      新学術領域「天然変性タンパク質の分子認識機構と機能発現」第1回国際シンポジウム
    • Place of Presentation
      はまぎんホール・ヴィアマーレ
    • Year and Date
      2011-01-27
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] Structural basis for recognition of histone modifications by UHRF12011

    • Author(s)
      有田恭平
    • Organizer
      構造エピゲノム研究会第3回ワークショップ
    • Place of Presentation
      理研横浜研究所交流棟ホール
    • Year and Date
      2011-04-25
    • Data Source
      KAKENHI-PUBLICLY-22113511
  • [Presentation] Structural basis for recognition of histone modifications by UHRF12011

    • Author(s)
      Kyohei Arita.
    • Organizer
      構造エピゲノム研究会第3回ワークショップ
    • Year and Date
      2011-04-25
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] Structural basis for recognition of epigenetic marks by UHRF12011

    • Author(s)
      Kyohei Arita, Kazya Sugita、Motoko Unoki、Ryuji Hamamoto、Shin Isogai, Mariko Ariyoshi、Hidehito Tochio、Masahiro Shirakawa
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      ホテル阪急エキスポパーク
    • Year and Date
      2011-06-07
    • Data Source
      KAKENHI-PUBLICLY-22113511
  • [Presentation] Structural basis for maintenance of DNA methylation and recognition of histone modifications by UHRF12011

    • Author(s)
      有田恭平(白川昌宏代理)
    • Organizer
      第34回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PUBLICLY-22113511
  • [Presentation] Structural basis for maintenance of DNA methylation and recognition of histone modifications by UHRF12011

    • Author(s)
      有田恭平(白川昌宏代理)
    • Organizer
      第34回日本分子生物学会
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] Structural basis for recognition of epigenetic modifications by UHRF12011

    • Author(s)
      Kyohei Arita.
    • Organizer
      新学術領域「天然変性タンパク質の分子認識機構と機能発現」第1回国際シンポジウム
    • Year and Date
      2011-01-27
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] Structural basis for recognition of epigenetic marks by UHRF12011

    • Author(s)
      Kyohei Arita, Kazya Sugita、Motoko Unoki、Ryuji Hamamoto、Shin Isogai、Mariko Ariyoshi、Hidehito Tochio、Masahiro Shirakawa
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      ホテル阪急エキスポパーク
    • Year and Date
      2011-06-07
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] Structural basis for recognition of epigenetic modifications by UHRF12011

    • Author(s)
      Kyohei Arita
    • Organizer
      新学術領域「天然変性タンパク質の分子認識機構と機能発現」第1回国際シンポジウム
    • Place of Presentation
      はまぎんホール・ヴィアマーレ
    • Year and Date
      2011-01-27
    • Data Source
      KAKENHI-PUBLICLY-22113511
  • [Presentation] UHRF1によるエピジェネティックマークの読み取り機構の構造生物学的基盤2010

    • Author(s)
      有田恭平, 杉田和也, 鵜木元香, 浜本隆二, 有吉真理子, 朽尾豪人, 白川昌宏
    • Organizer
      BMB2010
    • Place of Presentation
      神戸国際展示場
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] UHRF1によるエピジェネティックマークの読み取り機構の構造生物学的基盤2010

    • Author(s)
      有田恭平, 杉田和也, 鵜木元香, 浜本隆二, 有吉真理子, 杤尾豪人, 白川昌宏
    • Organizer
      BMB2010
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] UHRF1タンパク質によるヘミメチル化DNAとヒストン修飾の認識機構2010

    • Author(s)
      有田恭平, 杉田和也, 有吉真理子, 鵜木元香, 朽尾豪人, 中村祐輪, 白川昌宏
    • Organizer
      第4回日本エピジェネティクス研究会年会
    • Place of Presentation
      米子市文化ホール
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] UHRF1タンパク質によるヘミメチル化DNAとヒストン修飾の認識機構2010

    • Author(s)
      有田恭平, 杉田和也, 有吉真理子'鵜木元香'杤尾豪人'中村祐輔'白川昌宏
    • Organizer
      第4回日本エピジェネティクス研究会年会
    • Place of Presentation
      米子市文化ホール(招待講演)
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PUBLICLY-22113511
  • [Presentation] UHRF1によるエピジェネティックマークの読み取り機構の構造生物学的基盤2010

    • Author(s)
      有田恭平, 杉田和也, 鵜木元香, 浜本隆二, 有吉真理子, 杤尾豪人, 白川昌宏
    • Organizer
      BMB2010
    • Place of Presentation
      神戸国際展示場(招待講演)
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PUBLICLY-22113511
  • [Presentation] UHRF1タンパク質によるヘミメチル化DNAとヒストン修飾の認識機構2010

    • Author(s)
      有田恭平, 杉田和也, 有吉真理子, 鵜木元香, 杤尾豪人, 中村祐輔, 白川昌宏
    • Organizer
      第4回日本エピジェネティクス研究会年会
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-22687008
  • [Presentation] Structural basis for histone H3 recognition by UHRF1 PHD finger2009

    • Author(s)
      杉田和也, 有田恭平, 有吉眞理子, 栃尾豪人, 白川昌宏
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-21870015
  • [Presentation] Structural basis for recognition of H3K4 methylation status by the DNMT3A ADD domain2009

    • Author(s)
      大谷淳二, 南雲利之, 有田恭平, 稲本進, 有吉眞理子, 白川昌宏
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-21870015
  • [Presentation] Thermodynamic analysis of the hemi-methylated CpG DNA recognition by SRA domain of human NP952009

    • Author(s)
      菊川雄介, 杉田和也, 有田恭平, 有吉眞理子, 栃尾豪人, 鳥越秀峰, 白川昌宏
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-21870015
  • 1.  Nishiyama Atsuya (50378840)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 2.  NAKAMURA Fumio (10262023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  YAMASHITA Naoya (40508793)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  HASHIMOTO Hiroshi (40336590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  UNOKI Motoko (30525374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OGURA Atsuo (20194524)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YAMAGATA Kazuo (10361312)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  UEDA Koji (10509110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  SHARIF Jafar (00577968)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  Nakanishi Makoto (40217774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  河本 宏 (00343228)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  油谷 浩幸 (10202657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MAENOHARA Shoji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ARIYOSI Mariko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 15.  KODERA Noriyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  河添 好孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  小田 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  佐藤 衛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  田中 啓二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  白川 昌宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 21.  菊地 和也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  杤尾 豪人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  川上 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 24.  池上 貴久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  竹下 浩平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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