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KOSAKA Akemi  小坂 朱

ORCIDConnect your ORCID iD *help
Researcher Number 40561030
Affiliation (Current) 2025: 旭川医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2022 – 2025: 旭川医科大学, 医学部, 講師
2020: 旭川医科大学, 医学部, 講師
2016 – 2019: 旭川医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 49020:Human pathology-related / Human pathology
Except Principal Investigator
Basic Section 49020:Human pathology-related / Human pathology
Keywords
Principal Investigator
STING / TNBC / IL-6 / アゴニスト / I型インターフェロン / 免疫抑制 / がん免疫療法 / 腫瘍免疫 / 抗腫瘍免疫 / 抗腫瘍効果 / STINGアゴニスト / COX-2阻害薬 … More
Except Principal Investigator
… More 腫瘍免疫 / 単球由来樹状細胞 / がん所属リンパ節 / cGAS/STING/I型IFN / 癌免疫微小環境 / STING / cGAMP / I型インターフェロン / グリオーマ / 免疫監視機構 / 免疫逃避機構 / cancer vaccines Less
  • Research Projects

    (7 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (3 People)
  •  非炎症性腫瘍に対するSTINGとRIG-Iを標的としたがん免疫療法の開発Principal Investigator

    • Principal Investigator
      小坂 朱
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Asahikawa Medical College
  •  がん免疫治療の奏効率向上を目指した腫瘍微小環境内の良質な炎症状態の誘導戦略

    • Principal Investigator
      大栗 敬幸
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Asahikawa Medical College
  •  STINGアゴニストを用いたTNBCに対する効果的ながん免疫療法の開発Principal Investigator

    • Principal Investigator
      小坂 朱
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Asahikawa Medical College
  •  cGAS/STING/I型IFN経路を基軸とした癌免疫微小環境のホット化治療戦略

    • Principal Investigator
      小林 博也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Asahikawa Medical College
  •  Induction of type I IFN in the immunosuppressive tumor microenvironmentPrincipal Investigator

    • Principal Investigator
      Kosaka Akemi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Asahikawa Medical College
  •  Cancer immunotherapy by combining the selective COX-2 inhibitor and type I IFN signalingPrincipal Investigator

    • Principal Investigator
      KOSAKA Akemi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      Asahikawa Medical College
  •  Analysis of stealth antigens for developing tumor immunotherapy

    • Principal Investigator
      Kobayashi Hiroya
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Asahikawa Medical College

All 2018 2017

All Journal Article Patent

  • [Journal Article] Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site.2017

    • Author(s)
      Ohkuri T, Kosaka A, Ishibashi K, Kumai T, Hirata Y, Ohara K, Nagato T, Oikawa K, Aoki N, Harabuchi Y, Celis E, Kobayashi H.
    • Journal Title

      Cancer Immunology, Immunotherapy

      Volume: - Issue: 6 Pages: 705-716

    • DOI

      10.1007/s00262-017-1975-1

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19070, KAKENHI-PROJECT-16K19071
  • [Patent] がん抗原ペプチド2018

    • Inventor(s)
      小林博也、大栗敬幸、小坂朱
    • Industrial Property Rights Holder
      小林博也、大栗敬幸、小坂朱
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-024972
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K15244
  • [Patent] がん抗原ペプチド2017

    • Inventor(s)
      大栗敬幸、小林博也、小坂朱
    • Industrial Property Rights Holder
      大栗敬幸、小林博也、小坂朱
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-072183
    • Filing Date
      2017-03-18
    • Data Source
      KAKENHI-PROJECT-16K15244
  • 1.  Kobayashi Hiroya (90280867)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  大栗 敬幸 (70564061)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  長門 利純 (80431419)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results

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