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Takao Tomoka  高尾 知佳

… Alternative Names

TAKAO TOMOKA  高尾 知佳

高尾 知佳  タカオ トモカ

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Researcher Number 40612429
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6519-2301
Affiliation (Current) 2020: 岡山大学, 医歯薬学総合研究科, 助教
Affiliation (based on the past Project Information) *help 2020: 岡山大学, 医歯薬学総合研究科, 助教
2020: 慶應義塾大学, 医学部(信濃町), 共同研究員
2016 – 2019: 慶應義塾大学, 医学部(信濃町), 特任助教
2016: 慶應義塾大学, 医学部, 特任助教
2015: 京都大学, 医学(系)研究科(研究院), 研究員
2013: 京都大学, 医学(系)研究科(研究院), 研究員
2012: 九州大学, 環境発達医学研究センター, 学術研究員
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related
Except Principal Investigator
Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords
Principal Investigator
分化制御 / 胎盤 / 栄養膜幹細胞 / 分化制御シグナル / ヒト栄養膜幹細胞分化 / MET / Wnt/β-catenin / 間葉系幹細胞 / 間葉-上皮転換 / METモデル … More / 上皮プロモーター / Photoactivatable / CRISPR-Cas9 / reproduction / endometrium / in vivo model … More
Except Principal Investigator
Genome diversity / Endometrial cancer / MDM2 309 G/T SNP / AhR -130bp C/T SNP / AhR transcription / serum IL24 concentration / MDM2 / SNP / AHR / NF1C / 子宮体癌 / MDM2型 / シグナロソーム / -130C/T多型 / NFIC / 子宮筋腫 / MED12 / CRISPR/CAS9 / 生殖医学 / 幹細胞医学 / 脱細胞化 / 再細胞化 / 子宮 / 幹細胞 / ゲノム編集 / 再生医学 / 光制御 / 光操作 Less
  • Research Projects

    (7 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (23 People)
  •  幹細胞工学とゲノム編集の技術を用いた雌性生殖器官の機能・再生・疾患の光による制御Ongoing

    • Principal Investigator
      丸山 哲夫
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Keio University
  •  光活性型Creシステムを利用した生体内遺伝子操作法の開発Ongoing

    • Principal Investigator
      宝田 剛志
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Okayama University
  •  光応答性CRISPR/CAS9による生殖能の時間的制御モデルの構築Principal InvestigatorOngoing

    • Principal Investigator
      高尾 知佳
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Keio University
  •  Development and Molecular regulatory mechanism of mesenchymal epithelial transition (MET) modelPrincipal Investigator

    • Principal Investigator
      TAKAO Tomoka
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University
  •  Development of uterine leiomyoma model using CRISPR/CAS9 genome editing system

    • Principal Investigator
      MARUYAMA Tetsuo
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University
  •  The mechanism of signal for regulating differentiation in human trophoblast stem cellsPrincipal Investigator

    • Principal Investigator
      TAKAO TOMOKA
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kyoto University
  •  子宮内膜細胞の老化逸脱へのゲノム多様性の関与

    • Principal Investigator
      WAKE NORIO
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kyushu University

All 2019 2018 2015 2013 2012 2011

All Journal Article Presentation

  • [Journal Article] The orientation of a decellularized uterine scaffold determines the tissue topology and architecture of the regenerated uterus in rats.2019

    • Author(s)
      Miki Fumie、Maruyama Tetsuo、Miyazaki Kaoru、Takao Tomoka、Yoshimasa Yushi、Katakura Satomi、Hihara Hanako、Uchida Sayaka、Masuda Hirotaka、Uchida Hiroshi、Nagai Toshihiro、Shibata Shinsuke、Tanaka Mamoru
    • Journal Title

      Biol Reprod

      Volume: -

    • DOI

      10.1093/biolre/ioz004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05474, KAKENHI-PROJECT-17H04236, KAKENHI-PROJECT-16K11108, KAKENHI-PROJECT-16K15536, KAKENHI-PROJECT-17K19731, KAKENHI-PROJECT-16K20189
  • [Journal Article] Aryl hydrocarbon receptor SNP -130 C/T associates with dioxins susceptibility through regulating its receptor activity and downstream effectors including interleukin 24.2015

    • Author(s)
      Liu G, Asanoma K, Takao T, Tsukimori K, Uchi H, Furue M, Kato K, Wake N
    • Journal Title

      Toxicology Letters

      Volume: 232 Pages: 384-392

    • DOI

      10.1016/j.toxlet.2014.11.025

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23249075, KAKENHI-PROJECT-26462529
  • [Journal Article] Regulation Mechanism of TWIST1 Transcription by BHLHE40 and BHLHE41 in Cancer Cells.2015

    • Author(s)
      Asanoma K, Liu G, Yamane T, Miyanari Y, Takao T, Yagi H, Ohgami T, Ichinoe A, Sonoda K, Wake N, Kato K
    • Journal Title

      Mol Cell Biol.

      Volume: 35 Pages: 4096-4109

    • DOI

      10.1128/mcb.00678-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462529, KAKENHI-PROJECT-15K15608, KAKENHI-PUBLICLY-15H01517, KAKENHI-PROJECT-25462562
  • [Journal Article] The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia.2015

    • Author(s)
      Aijima R, Wang B, Takao T, Mihara H, Kashio M, Ohsaki Y, Zhang JQ, Mizuno A, Suzuki M, Yamashita Y, Masuko S, Goto M, Tominaga M, Kido MA
    • Journal Title

      FASEB J.

      Volume: 29 Pages: 182-192

    • DOI

      10.1096/fj.14-251314

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J03310, KAKENHI-PROJECT-25860172, KAKENHI-PROJECT-26670870, KAKENHI-PROJECT-15H02501, KAKENHI-PROJECT-15H06497, KAKENHI-PROJECT-25462562
  • [Journal Article] Establishment of a new diagnostic method for hydropic villi by using TSSC3 antibody.2013

    • Author(s)
      Wake N, Takao T, Asanoma K, Kato H
    • Journal Title

      J Obstet Gynaecol Res

      Volume: 39(7) Pages: 1230-1235

    • DOI

      10.1111/jog.12100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249075, KAKENHI-PROJECT-23592405, KAKENHI-PROJECT-25462562
  • [Journal Article] Oxidative stress produced by xanthine oxidase induces apoptosis in human extravillous trophoblast cells.2013

    • Author(s)
      Murata M, Fukushima K, Takao T, Seki H, Takeda S, Wake N.
    • Journal Title

      J Reprod Dev.

      Volume: 59(1) Pages: 7-13

    • NAID

      10031156805

    • Data Source
      KAKENHI-PROJECT-23249075
  • [Journal Article] The maternally expressed gene Tssc3 regulates the expression of MASH2 transcription factor in mouse trophoblast stem cells through the AKT-Sp1 signaling pathway.2012

    • Author(s)
      Takao T, Asanoma K, Tsunematsu R, Kato K, Wake N.
    • Journal Title

      Journal of biological chemistry.

      Volume: 287(51) Pages: 42685-42694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249075
  • [Journal Article] Lsolation and Characterization of Human Trophoblast Side-Population (SP) Cells in Primary Villous Cytotrophoblasts and HTR-8/SVneo Cell Line2011

    • Author(s)
      Takao T, Asanoma K, Kato K, Fukushima K, Tsunematsu R, Hirakawa T, Matsumura S, Seki H, Takeda S, Wake N
    • Journal Title

      PLoS One

      Volume: 6(7)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249075
  • [Journal Article] Sodium butyrate inhibits the self-renewal capacity of endometrial tumor side-population cells by inducing a DNA damage response2011

    • Author(s)
      Kato K, Kuhara A, Yoneda T, Inoue T, Takao T, Ohgami T, Dan L, Kuboyama A, Kusunoki S, Takeda S, Wake N
    • Journal Title

      MolCancer Ther

      Volume: 10(8) Pages: 1430-1439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249075
  • [Presentation] P2RY is involved in the migration and invasion of human extravillous trophoblast.2019

    • Author(s)
      Tetsuo Maruyama, Satomi Katakura, Tomoka Takao, Toru Arase, Yushi Yoshimasa, Shoko Tomisato, Sayaka Uchida, Hirotaka Masuda, Hiroshi Uchida, Mamoru Tanaka
    • Organizer
      Society for Reproductive Investigation 66th Annual Scientific Meeting(SRI2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20189
  • [Presentation] Anovel approach to treat emdometriosis via targeting epithelial-mesenchymal transition.2018

    • Author(s)
      Hirotaka Masuda, Masataka Furuya, Tetsuo Maruyama, Fumie Miki, Satomi Katakura, Yushi Yoshimasa, Sayaka Uchida, Hiroshi Uchida, Tomoka Takao, Hidetaka Katabuchi, Mamoru Tanaka, Daisuke Aoki
    • Organizer
      第70回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-16K20189
  • [Presentation] Extravillous trophoblastの新しいマーカーとしてのG蛋白共役型受容体P2RY14とその細胞浸潤における役割.2018

    • Author(s)
      片倉慧美,丸山哲夫,高尾知佳,瀬田康弘,吉政佑之,富里祥子,三木史恵,内田明花,升田博隆,内田 浩,田中 守,青木大輔
    • Organizer
      第70回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-16K20189
  • [Presentation] Attempts to establish screening system for identification of drugs targeting human uterine endometrial cancer stem-like cells.2018

    • Author(s)
      Tetsuo Maruyama, Tomoka Takao, Hirotaka Masuda, Fumie Miki, Sayaka Uchida, Hiroshi Uchida, Mamoru Tanaka
    • Organizer
      nternational Society for Stem Cell Research 2018 annual meeting (ISSCR2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20189
  • [Presentation] 子宮体癌細胞の幹様細胞とそれを治療標的とする既存薬の探索.2018

    • Author(s)
      高尾知佳,升田博隆,三木史恵,片倉慧美,吉政佑之,富里祥子,内田明花,内田 浩,田中 守,丸山哲夫
    • Organizer
      第41回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-16K20189
  • [Presentation] ヒト正常子宮平滑筋細胞に対する子宮筋腫関連遺伝子MED12の変異導入による機能的病因解析.2018

    • Author(s)
      高尾知佳,丸山哲夫,内田 浩,内田明花,三木史恵,片倉慧美,吉政佑之,富里祥子,升田博隆,田中 守
    • Organizer
      第23回日本生殖内分泌学会
    • Data Source
      KAKENHI-PROJECT-16K20189
  • [Presentation] CRISPR/CAS9システムによりMED12変異を導入したヒト子宮筋腫モデルの開発の試み.2018

    • Author(s)
      高尾知佳,丸山哲夫,小野政徳,内田 浩,升田博隆,内田明花,三木史恵,片倉慧美,吉政佑之,藤原 浩,田中 守,青木大輔
    • Organizer
      第70回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-16K20189
  • [Presentation] 子宮内膜幹細胞と上皮間葉転換をターゲットとした非内分泌的な子宮内膜症の新規治療.2018

    • Author(s)
      升田博隆,古谷正敬,丸山哲夫,高尾知佳,内田 浩,内田明花,吉政佑之.片倉慧美,吉村泰典,片渕秀隆,田中 守
    • Organizer
      第23回日本生殖内分泌学会
    • Data Source
      KAKENHI-PROJECT-16K20189
  • [Presentation] ヒト子宮内膜症モデル細胞におけるAd4BP/SF-1の新たな役割2015

    • Author(s)
      高尾知佳, 梶谷宇
    • Organizer
      第88回日本内分泌学会学術集会
    • Place of Presentation
      東京都ホテルニューオータニ東京
    • Year and Date
      2015-04-23
    • Data Source
      KAKENHI-PROJECT-25462562
  • 1.  WAKE NORIO (60091584)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 2.  MARUYAMA Tetsuo (10209702)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  内田 浩 (90286534)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  升田 博隆 (80317198)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  佐藤 守俊 (00323501)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  浅野間 和夫 (30380413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  劉 格 (50647998)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  恒松 良祐 (20380529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  井上 貴史 (70380417)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  小野 政徳 (70348712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  荒瀬 透 (20348709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  宮崎 薫 (90445370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  宝田 剛志 (30377428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  山田 大祐 (50733680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MASUDA Hirotaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  MIKI Fumie
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 17.  YOSHIMASA Yushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 18.  加藤 聖子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  田中 守
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  加塩 麻紀子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  城戸 瑞穂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  富永 真琴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  合島 怜央奈
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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