Takao Tomoka 高尾知佳

… Alternative Names

Researcher Number	40612429
Other IDs	https://orcid.org/0000-0002-6519-2301
Affiliation (Current)	2020: 岡山大学, 医歯薬学総合研究科, 助教
Affiliation (based on the past Project Information) *help	2020: 岡山大学, 医歯薬学総合研究科, 助教 2020: 慶應義塾大学, 医学部(信濃町), 共同研究員 2016 – 2019: 慶應義塾大学, 医学部(信濃町), 特任助教 2016: 慶應義塾大学, 医学部, 特任助教 2015: 京都大学, 医学(系)研究科(研究院), 研究員 2013: 京都大学, 医学(系)研究科(研究院), 研究員 2012: 九州大学, 環境発達医学研究センター, 学術研究員
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords	Principal Investigator 分化制御 / 胎盤 / 栄養膜幹細胞 / 分化制御シグナル / ヒト栄養膜幹細胞分化 / MET / Wnt/β-catenin / 間葉系幹細胞 / 間葉-上皮転換 / METモデル … More Except Principal Investigator Genome diversity / Endometrial cancer / MDM2 309 G/T SNP / AhR -130bp C/T SNP / AhR transcription / serum IL24 concentration / MDM2 / SNP / AHR / NF1C / 子宮体癌 / MDM2型 / シグナロソーム / -130C/T多型 / NFIC / 子宮筋腫 / MED12 / CRISPR/CAS9 / 生殖医学 / 幹細胞医学 / 脱細胞化 / 再細胞化 / 子宮 / 幹細胞 / ゲノム編集 / 再生医学 / 光制御 / 光操作 Less

幹細胞工学とゲノム編集の技術を用いた雌性生殖器官の機能・再生・疾患の光による制御Ongoing
- Principal Investigator
  
  丸山哲夫
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Keio University
光活性型Creシステムを利用した生体内遺伝子操作法の開発Ongoing
- Principal Investigator
  
  宝田剛志
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Okayama University
光応答性CRISPR/CAS9による生殖能の時間的制御モデルの構築Principal InvestigatorOngoing
- Principal Investigator
  
  高尾知佳
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Keio University
Development and Molecular regulatory mechanism of mesenchymal epithelial transition (MET) modelPrincipal Investigator
- Principal Investigator
  
  TAKAO Tomoka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Development of uterine leiomyoma model using CRISPR/CAS9 genome editing system
- Principal Investigator
  
  MARUYAMA Tetsuo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
The mechanism of signal for regulating differentiation in human trophoblast stem cellsPrincipal Investigator
- Principal Investigator
  
  TAKAO TOMOKA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyoto University
子宮内膜細胞の老化逸脱へのゲノム多様性の関与
- Principal Investigator
  
  WAKE NORIO
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University

All 2019 2018 2015 2013 2012 2011

All Journal Article Presentation

[Journal Article] The orientation of a decellularized uterine scaffold determines the tissue topology and architecture of the regenerated uterus in rats.2019
- Author(s)
  Miki Fumie、Maruyama Tetsuo、Miyazaki Kaoru、Takao Tomoka、Yoshimasa Yushi、Katakura Satomi、Hihara Hanako、Uchida Sayaka、Masuda Hirotaka、Uchida Hiroshi、Nagai Toshihiro、Shibata Shinsuke、Tanaka Mamoru
- Journal Title
  
  Biol Reprod
  
  Volume: -
- DOI
  10.1093/biolre/ioz004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05474, KAKENHI-PROJECT-17H04236, KAKENHI-PROJECT-16K11108, KAKENHI-PROJECT-16K15536, KAKENHI-PROJECT-17K19731, KAKENHI-PROJECT-16K20189
[Journal Article] Aryl hydrocarbon receptor SNP -130 C/T associates with dioxins susceptibility through regulating its receptor activity and downstream effectors including interleukin 24.2015
- Author(s)
  Liu G, Asanoma K, Takao T, Tsukimori K, Uchi H, Furue M, Kato K, Wake N
- Journal Title
  
  Toxicology Letters
  
  Volume: 232 Pages: 384-392
- DOI
  10.1016/j.toxlet.2014.11.025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23249075, KAKENHI-PROJECT-26462529
[Journal Article] Regulation Mechanism of TWIST1 Transcription by BHLHE40 and BHLHE41 in Cancer Cells.2015
- Author(s)
  Asanoma K, Liu G, Yamane T, Miyanari Y, Takao T, Yagi H, Ohgami T, Ichinoe A, Sonoda K, Wake N, Kato K
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 35 Pages: 4096-4109
- DOI
  10.1128/mcb.00678-15
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462529, KAKENHI-PROJECT-15K15608, KAKENHI-PUBLICLY-15H01517, KAKENHI-PROJECT-25462562
[Journal Article] The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia.2015
- Author(s)
  Aijima R, Wang B, Takao T, Mihara H, Kashio M, Ohsaki Y, Zhang JQ, Mizuno A, Suzuki M, Yamashita Y, Masuko S, Goto M, Tominaga M, Kido MA
- Journal Title
  
  FASEB J.
  
  Volume: 29 Pages: 182-192
- DOI
  10.1096/fj.14-251314
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J03310, KAKENHI-PROJECT-25860172, KAKENHI-PROJECT-26670870, KAKENHI-PROJECT-15H02501, KAKENHI-PROJECT-15H06497, KAKENHI-PROJECT-25462562
[Journal Article] Establishment of a new diagnostic method for hydropic villi by using TSSC3 antibody.2013
- Author(s)
  Wake N, Takao T, Asanoma K, Kato H
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 39(7) Pages: 1230-1235
- DOI
  10.1111/jog.12100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249075, KAKENHI-PROJECT-23592405, KAKENHI-PROJECT-25462562
[Journal Article] Oxidative stress produced by xanthine oxidase induces apoptosis in human extravillous trophoblast cells.2013
- Author(s)
  Murata M, Fukushima K, Takao T, Seki H, Takeda S, Wake N.
- Journal Title
  
  J Reprod Dev.
  
  Volume: 59(1) Pages: 7-13
- NAID
  10031156805
- Data Source
  KAKENHI-PROJECT-23249075
[Journal Article] The maternally expressed gene Tssc3 regulates the expression of MASH2 transcription factor in mouse trophoblast stem cells through the AKT-Sp1 signaling pathway.2012
- Author(s)
  Takao T, Asanoma K, Tsunematsu R, Kato K, Wake N.
- Journal Title
  
  Journal of biological chemistry.
  
  Volume: 287(51) Pages: 42685-42694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249075
[Journal Article] Lsolation and Characterization of Human Trophoblast Side-Population (SP) Cells in Primary Villous Cytotrophoblasts and HTR-8/SVneo Cell Line2011
- Author(s)
  Takao T, Asanoma K, Kato K, Fukushima K, Tsunematsu R, Hirakawa T, Matsumura S, Seki H, Takeda S, Wake N
- Journal Title
  
  PLoS One
  
  Volume: 6(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249075
[Journal Article] Sodium butyrate inhibits the self-renewal capacity of endometrial tumor side-population cells by inducing a DNA damage response2011
- Author(s)
  Kato K, Kuhara A, Yoneda T, Inoue T, Takao T, Ohgami T, Dan L, Kuboyama A, Kusunoki S, Takeda S, Wake N
- Journal Title
  
  MolCancer Ther
  
  Volume: 10(8) Pages: 1430-1439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249075
[Presentation] P2RY is involved in the migration and invasion of human extravillous trophoblast.2019
- Author(s)
  Tetsuo Maruyama, Satomi Katakura, Tomoka Takao, Toru Arase, Yushi Yoshimasa, Shoko Tomisato, Sayaka Uchida, Hirotaka Masuda, Hiroshi Uchida, Mamoru Tanaka
- Organizer
  Society for Reproductive Investigation 66th Annual Scientific Meeting（SRI2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20189
[Presentation] Anovel approach to treat emdometriosis via targeting epithelial-mesenchymal transition.2018
- Author(s)
  Hirotaka Masuda, Masataka Furuya, Tetsuo Maruyama, Fumie Miki, Satomi Katakura, Yushi Yoshimasa, Sayaka Uchida, Hiroshi Uchida, Tomoka Takao, Hidetaka Katabuchi, Mamoru Tanaka, Daisuke Aoki
- Organizer
  第70回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-16K20189
[Presentation] Extravillous trophoblastの新しいマーカーとしてのG蛋白共役型受容体P2RY14とその細胞浸潤における役割．2018
- Author(s)
  片倉慧美，丸山哲夫，高尾知佳，瀬田康弘，吉政佑之，富里祥子，三木史恵，内田明花，升田博隆，内田　浩，田中　守，青木大輔
- Organizer
  第70回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-16K20189
[Presentation] Attempts to establish screening system for identification of drugs targeting human uterine endometrial cancer stem-like cells.2018
- Author(s)
  Tetsuo Maruyama, Tomoka Takao, Hirotaka Masuda, Fumie Miki, Sayaka Uchida, Hiroshi Uchida, Mamoru Tanaka
- Organizer
  nternational Society for Stem Cell Research 2018 annual meeting (ISSCR2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20189
[Presentation] 子宮体癌細胞の幹様細胞とそれを治療標的とする既存薬の探索．2018
- Author(s)
  高尾知佳，升田博隆，三木史恵，片倉慧美，吉政佑之，富里祥子，内田明花，内田　浩，田中　守，丸山哲夫
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K20189
[Presentation] ヒト正常子宮平滑筋細胞に対する子宮筋腫関連遺伝子MED12の変異導入による機能的病因解析．2018
- Author(s)
  高尾知佳，丸山哲夫，内田　浩，内田明花，三木史恵，片倉慧美，吉政佑之，富里祥子，升田博隆，田中　守
- Organizer
  第23回日本生殖内分泌学会
- Data Source
  KAKENHI-PROJECT-16K20189
[Presentation] CRISPR/CAS9システムによりMED12変異を導入したヒト子宮筋腫モデルの開発の試み．2018
- Author(s)
  高尾知佳，丸山哲夫，小野政徳，内田　浩，升田博隆，内田明花，三木史恵，片倉慧美，吉政佑之，藤原　浩，田中　守，青木大輔
- Organizer
  第70回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-16K20189
[Presentation] 子宮内膜幹細胞と上皮間葉転換をターゲットとした非内分泌的な子宮内膜症の新規治療．2018
- Author(s)
  升田博隆，古谷正敬，丸山哲夫，高尾知佳，内田　浩，内田明花，吉政佑之．片倉慧美，吉村泰典，片渕秀隆，田中　守
- Organizer
  第23回日本生殖内分泌学会
- Data Source
  KAKENHI-PROJECT-16K20189
[Presentation] ヒト子宮内膜症モデル細胞におけるAd4BP/SF-1の新たな役割2015
- Author(s)
  高尾知佳, 梶谷宇
- Organizer
  第88回日本内分泌学会学術集会
- Place of Presentation
  東京都ホテルニューオータニ東京
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25462562

1. WAKE NORIO (60091584)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. MARUYAMA Tetsuo (10209702)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 内田浩 (90286534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 升田博隆 (80317198)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 佐藤守俊 (00323501)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 浅野間和夫 (30380413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 劉格 (50647998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 恒松良祐 (20380529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 井上貴史 (70380417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 小野政徳 (70348712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 荒瀬透 (20348709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 宮崎薫 (90445370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 宝田剛志 (30377428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 山田大祐 (50733680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MASUDA Hirotaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. MIKI Fumie

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. YOSHIMASA Yushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 加藤聖子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 田中守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 加塩麻紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 城戸瑞穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 富永真琴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 合島怜央奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takao Tomoka 高尾 知佳

TAKAO TOMOKA 高尾 知佳

高尾 知佳 タカオ トモカ

Research Projects

Research Products

Co-Researchers

幹細胞工学とゲノム編集の技術を用いた雌性生殖器官の機能・再生・疾患の光による制御Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

光活性型Creシステムを利用した生体内遺伝子操作法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

光応答性CRISPR/CAS9による生殖能の時間的制御モデルの構築Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and Molecular regulatory mechanism of mesenchymal epithelial transition (MET) modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of uterine leiomyoma model using CRISPR/CAS9 genome editing system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of signal for regulating differentiation in human trophoblast stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

子宮内膜細胞の老化逸脱へのゲノム多様性の関与

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The orientation of a decellularized uterine scaffold determines the tissue topology and architecture of the regenerated uterus in rats.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aryl hydrocarbon receptor SNP -130 C/T associates with dioxins susceptibility through regulating its receptor activity and downstream effectors including interleukin 24.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation Mechanism of TWIST1 Transcription by BHLHE40 and BHLHE41 in Cancer Cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a new diagnostic method for hydropic villi by using TSSC3 antibody.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oxidative stress produced by xanthine oxidase induces apoptosis in human extravillous trophoblast cells.2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The maternally expressed gene Tssc3 regulates the expression of MASH2 transcription factor in mouse trophoblast stem cells through the AKT-Sp1 signaling pathway.2012

Author(s)

Takao Tomoka 高尾知佳

TAKAO TOMOKA 高尾知佳

高尾知佳タカオトモカ