Shoichiro Kokabu 古株彰一郎

Researcher Number	30448899
Affiliation *help	2014 – 2018 : 九州歯科大学, 歯学部, 准教授
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 57010:Oral biological science-related / Surgical dentistry Except Principal Investigator Surgical dentistry / Morphological basic dentistry / Functional basic dentistry / Oral Science and related fields / Basic Section 57010:Oral biological science-related / Otorhinolaryngology / Basic Section 56020:Orthopedics-related / Orthodontics/Pediatric dentistry / Basic Section 57070:Developmental dentistry-related
Keywords	Principal Investigator 骨格筋 / サルコペニア / 再生医学 / 細胞増殖 / 老化 / 骨 / 骨格筋組織幹細胞 / サテライト細胞 / 歯学 / 間葉系幹細胞 … More Except Principal Investigator p130Cas / 骨吸収 / 破骨細胞 / NF-κB / 骨代謝 / 骨芽細胞 / 上皮間葉移行 / 活性化機構 / 骨誘導因子 / 骨細胞 / 骨・神経・血管 / 口唇裂 / 浸潤 / p65サブユニット / 顎口腔機能 / 口唇口蓋裂 / 骨格筋 / 血管系 / 潰瘍性口内炎 / 平衡感覚機能 / 遺伝子導入 / シゾン / netrin-4 / 分化 / netrin-1 / 骨 / 骨減少症 / 骨再生 / BMP / 創薬 / 脳 / 味覚受容体 / ネットワーク / NF-kB / 遊走能 / 小児 / 運動器疾患 / ステロイド / 歯肉癌 / 口腔扁平上皮癌 / 悪性黒色腫 / E-Cadherin / semaphorin 3A / リン酸化 / ビタミン / 遺伝子網羅的解析 / NKG2Dリガンド / 成長 / 口腔生理学 / 顎顔面 / 転移 / 唾液腺 / MICA/B / ネットワーク機構 / TGF-β / 分化能 / 血管内皮細胞 / CDK6 / 歯の石灰化 / 機能獲得 / 神経系 / 神経芽細胞 / ALP / 超音波 Less

25(OH)D3は神経系を介して平衡感覚機能を向上させるかOngoing
- Principal Investigator
  
  榎木祐一郎
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Saitama Medical University
Src-Casを中心とした骨吸収活性調節におけるKifファミリー分子の役割解明Ongoing
- Principal Investigator
  
  松原琢磨
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu Dental College
オートクリン・パラクラリン因子BMP-3bが担う骨格筋恒常性維持機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  古株彰一郎
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu Dental College
口腔機能・形態の発育を担う顎顔面骨格筋局所に発現するアミノ酸センサーの役割Ongoing
- Principal Investigator
  
  森川和政
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Iwate Medical University
悪性黒色腫の上皮-間葉移行におけるBMPの役割と新規浸潤・転移モデルの確立Ongoing
- Principal Investigator
  
  松尾拡
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu Dental College
潰瘍性口内炎の抑制を目的とした上皮細胞へのシゾンAPX遺伝子導入の有効性Ongoing
- Principal Investigator
  
  人見涼露
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu Dental College
口腔扁平上皮癌上皮間葉移行におけるp130 Casの役割と治療標的としての可能性Ongoing
- Principal Investigator
  
  吉岡泉
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu Dental College
副作用の少ない小児ステロイド性顎骨骨粗鬆症治療における骨吸収阻害薬の開発Ongoing
- Principal Investigator
  
  牧憲司
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Kyushu Dental College
運動器疾患治療のための中枢・末梢機能の活性化を担う分子基盤の解明と治療法の開発Ongoing
- Principal Investigator
  
  佐藤毅
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Saitama Medical University
The Commonality in the organogenesis of p130Cas, which controls differentiation from morphogenesisOngoing
- Principal Investigator
  
  自見英治郎
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Challenging Research (Exploratory)
- Research Field
  
  Oral Science and related fields
- Research Institution
  Kyushu University
タンパク質相互作用を標的とした骨形成促進効果を持つ低分子化合物の開発Ongoing
- Principal Investigator
  
  張皿
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu Dental College
NF-κBシグナルを標的とした骨格筋萎縮性疾患治療の分子基盤形成Principal InvestigatorOngoing
- Principal Investigator
  
  古株彰一郎
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu Dental College
顎顔面発生過程における低酸素ストレス抵抗性因子の解析Ongoing
- Principal Investigator
  
  中富満城
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu Dental College
A novel regulatory mechanism of NF-kB signaling
- Principal Investigator
  
  Eijiro Jimi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu Dental College
Molecular mechanisms of nerve-vessel-bone network
- Principal Investigator
  
  SATO Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Saitama Medical University
Comprehensive analysis of expressed molecules in mandibular gingival cancer and elucidation of involvement of netrin 1
- Principal Investigator
  
  NAKAHIRA MITSUHIKO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Saitama Medical University
The molecular basis of novel bone regeneration methods by regulating TLE3Principal Investigator
- Principal Investigator
  
  Shoichiro Kokabu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
  Surgical dentistry
- Research Institution
  Kyushu Dental College

All 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] 骨髄間葉系幹細胞の運命決定メカニズムの研究.2015
- Author(s)
  古株彰一郎
- Journal Title
  
  九州歯科学会雑誌
  
  Volume : 69 Pages : 1-8
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] NF-κBシグナルは除神経による骨格筋萎縮初期に亢進する2016
- Author(s)
  古株彰一郎, 中富千尋, 松原琢磨, 人見涼露, 自見英治郎
- Organizer
  第76回九州歯科学会総会・学術大会
- Place of Presentation
  北九州
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-16K20424
[Presentation] TLE3によるMyoD の転写活性制御機構2016
- Author(s)
  古株彰一郎，中富千尋，松原琢磨，自見英治郎
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K20424
[Presentation] Identification of interacting region of Smad4 and NF-κB/p652016
- Author(s)
  浦田真梨子、松原琢磨、竹内　弘、中富千尋、平田-土屋志津、古株彰一郎、張　皿、北村知昭、自見英治郎
- Organizer
  第58回　歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K11456
[Presentation] NF-κBシグナル亢進と除神経性骨格筋萎縮2016
- Author(s)
  古株彰一郎, 中富千尋, 松原琢磨, 自見英治郎
- Organizer
  第34回日本骨代謝学会学術大会
- Place of Presentation
  大阪
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K20424
[Presentation] 骨芽細胞と神経芽細胞は相互に分化を促進させる2016
- Author(s)
  塘田健人、佐藤毅、大久保正彦、榎木祐一郎、古株彰一郎、依田哲也
- Organizer
  第70回日本口腔科学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-26293432
[Presentation] TLE3による筋分化調節機構2015
- Author(s)
  古株彰一郎、中富千尋、浦田真梨子、松原琢磨、片桐岳信、自見英治郎
- Organizer
  第57回歯科基礎医学会学術大会・総会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] TLE3結合因子の探索とその機能解析2015
- Author(s)
  古株彰一郎、杉山悟郎、浦田真梨子、中富千尋、自見英治郎
- Organizer
  第75回九州歯科学会総会・学術大会
- Place of Presentation
  北九州
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] Semaphorin 3A は cdk6 タンパク質発現の低下と STAT3 の tyrosine 705 リン酸化阻害を伴い骨細胞の細胞突起を伸長させる2015
- Author(s)
  新村昌弘、佐藤毅、林直樹、大久保正彦、榎木祐一郎、古株彰一郎、依田哲也
- Organizer
  第57回歯科基礎医学会学術大会・総会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] 新たな骨形成促進薬の探索とその分子メカニズム2015
- Author(s)
  浦田真梨子、古株彰一郎、杉山悟郎、平田-土屋志津、諸冨孝彦、北村知昭、自見英治郎
- Organizer
  第75回九州歯科学会総会・学術大会
- Place of Presentation
  北九州市
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] TLE3はMyoDの転写活性を調節する2015
- Author(s)
  古株彰一郎、佐藤　毅、榎木祐一郎、片桐岳信、自見英治郎
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] 軟骨内骨化および骨成長における NF-κB の時間・空間的制御機構の解明2015
- Author(s)
  中富千尋,浦田真梨子,松原琢磨,古株彰一郎,自見英治郎
- Organizer
  第57回歯科基礎医学会学術大会・総会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] 破骨細胞アクチンリングに局在する新規分子 PPP1r182015
- Author(s)
  松原琢磨, 金原正敬、前田敏博、吉澤光弘、中富千尋、古株彰一郎、自見英治郎、山本照子
- Organizer
  第57回歯科基礎医学会学術大会・総会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] Geranylgeraniol は骨芽細胞分化を促進する2015
- Author(s)
  浦田真梨子、古株彰一郎、中富千尋、松原琢磨、平田-土屋志津、諸冨孝彦、北村知昭、自見英治郎
- Organizer
  第57回歯科基礎医学会学術大会・総会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] Groucho/TLE はMyoDの転写活性を調節し筋分化を制御する2014
- Author(s)
  古株彰一郎、杉山悟郎、佐藤毅、依田哲也、片桐岳信、自見英治郎
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26870543
[Presentation] Netrin4を介した血管内皮細胞による新たな骨代謝調節機構と骨粗鬆症に対する臨床応用
- Author(s)
  榎木祐一郎，佐藤毅，林直樹，北村智久，大久保正彦，古株彰一郎，福島洋介，新村昌弘，依田哲也
- Organizer
  第68回日本口腔科学会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2014-05-07 – 2014-05-09
- Data Source
  KAKENHI-PROJECT-26293432

1. Eijiro Jimi (40276598)

# of Collaborated Projects : 8results

# of Collaborated Products : 1results
2. 松原琢磨 (00423137)

# of Collaborated Projects : 6results

# of Collaborated Products : 1results
3. SATO Tsuyoshi (60406494)

# of Collaborated Projects : 5results

# of Collaborated Products : 2results
4. 松尾拡 (70238971)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
5. 中富満城 (10571771)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. 人見涼露 (70548924)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
7. 臼井通彦 (10453630)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. 張皿 (00326472)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
9. OKAZAKI Yasushi (80280733)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. SUDA Tatsuo (90014034)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. NISHIHARA Tatsuji (80192251)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. YODA Testuya (60242210)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
13. NAKAHIRA MITSUHIKO (10253353)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. 竹田秀 (30376727)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. 水野洋介 (30406532)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. 松本征仁 (90321819)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. 瀬田祐司 (90291616)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. 豊野孝 (10311929)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 片岡真司 (80364149)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. 福島秀文 (70412624)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. 渡邉誠之 (10201196)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. 矢田直美 (60468022)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. 小野堅太郎 (40316154)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. 松本謙一郎 (10297046)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. 吉岡泉 (10305823)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
26. 大澤賢次 (70638238)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
27. 牧憲司 (60209400)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
28. 青木和広 (40272603)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
29. 有吉渉 (40405551)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
30. 榎木祐一郎 (30734199)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
31. 津川尚子 (30207352)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
32. 日野純 (40260351)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
33. 小野悠介 (60601119)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
34. 森川和政 (70514686)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

Shoichiro Kokabu 古株 彰一郎

Research Projects

Research Products

Co-Researchers

25(OH)D3は神経系を介して平衡感覚機能を向上させるかOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Src-Casを中心とした骨吸収活性調節におけるKifファミリー分子の役割解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

オートクリン・パラクラリン因子BMP-3bが担う骨格筋恒常性維持機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

口腔機能・形態の発育を担う顎顔面骨格筋局所に発現するアミノ酸センサーの役割Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

悪性黒色腫の上皮-間葉移行におけるBMPの役割と新規浸潤・転移モデルの確立Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

潰瘍性口内炎の抑制を目的とした上皮細胞へのシゾンAPX遺伝子導入の有効性Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

口腔扁平上皮癌上皮間葉移行におけるp130 Casの役割と治療標的としての可能性Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

副作用の少ない小児ステロイド性顎骨骨粗鬆症治療における骨吸収阻害薬の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

運動器疾患治療のための中枢・末梢機能の活性化を担う分子基盤の解明と治療法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Commonality in the organogenesis of p130Cas, which controls differentiation from morphogenesisOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

タンパク質相互作用を標的とした骨形成促進効果を持つ低分子化合物の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NF-κBシグナルを標的とした骨格筋萎縮性疾患治療の分子基盤形成Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

顎顔面発生過程における低酸素ストレス抵抗性因子の解析Ongoing

Principal Investigator

Project Period (FY)

Research Category

Shoichiro Kokabu 古株彰一郎