Tsunekawa Shin 恒川新

… Alternative Names

TSUNEKAWA Shin 恒川新

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Researcher Number	40612768
Other IDs
Affiliation (Current)	2025: 岐阜大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2023: 愛知医科大学, 医学部, 教授 2017 – 2022: 愛知医科大学, 医学部, 准教授 2016: 愛知医科大学, 医学部, 講師 2012 – 2015: 名古屋大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Metabolomics / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 54040:Metabolism and endocrinology-related
Keywords	Principal Investigator 糖尿病 / カテコラミン / 自己免疫 / 低血圧 / 移植・再生医療 / 組織幹細胞 / 膵島移植 / インスリン / 糖毒性 / メチレーション / エピジェネティクス … More Except Principal Investigator … More ヒト乳歯歯髄幹細胞 / 歯髄幹細胞 / 再生医療 / 免疫制御 / 間葉系幹細胞 / 膵島移植 / 分泌因子 / 糖尿病性合併症 / 血管新生 / ヒト臍帯静脈内皮細胞 / 糖尿病神経障害 / 糖尿病性神経障害 / ＧＬＰ－１ / ＳＧＬＴ１ / ＧＩＰ / SGLT-1 / ＫＡＴＰ　ｃｈａｎｎｅｌ / フルクトース / グルコース / insulin / SGLT1 / GLP-1 / GIP / fructose / glucose / KATP channel Less

ヒト乳歯歯髄幹細胞を用いた膵島オルガノイドによる画期的膵島移植プロトコールの開発
- Principal Investigator
  
  石山宏平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Aichi Medical University
自己免疫性モノアミン合成障害による新規低血圧疾患概念の確立Principal Investigator
- Principal Investigator
  
  恒川新
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Aichi Medical University
Development of Novel Therapies for Diabetic Ischemic Diseases using Secreted Factors from Stem Cells
- Principal Investigator
  
  Kamiya Hideki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Aichi Medical University
Development of the new treatment for diabetic neuropathy using somatic stem cells and their secreted factors
- Principal Investigator
  
  Hideki Kamiya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Aichi Medical University
The co-transplantation of Islets with Dental Pulp Stem Cells Improved Survival and Function of Transplanted Beta-CellsPrincipal Investigator
- Principal Investigator
  
  Tsunekaewa Shin
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Aichi Medical University
Role of the KATP channel in enteroendocrine cells and absorptive epithelial cells
- Principal Investigator
  
  Yusuke Seino
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya University
Long-Term Pancreatic Beta Cell Exposure To High Levels of Glucose but not Palmitate induces DNA Methylation within the Insulin Gene Promoter and represses Transcriptional ActivityPrincipal Investigator
- Principal Investigator
  
  TSUNEKAWA Shin
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya University

All 2020 2019 2018 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Secreted factors from stem cells of human exfoliated deciduous teeth directly activate endothelial cells to promote all processes of angiogenesis2020
- Author(s)
  Makoto Kato, Shin Tsunekawa, Nobuhisa Nakamura, Emiri Miura-Yura, \Yoshiro Kato, Takako Izumoto-Akita, Akihito Yamamoto, Keiko Naruse, Jiro Nakamura, Hideki Kamiya, et al.
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 11 Pages: 2385-2385
- DOI
  10.3390/cells9112385
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10121, KAKENHI-PROJECT-20K08874
[Journal Article] Secreted factors from cultured dental pulp stem cells promoted neurite outgrowth of dorsal root ganglion neurons and ameliorated neural functions in streptozotocin‐induced diabetic mice2019
- Author(s)
  Miura‐Yura Emiri、Tsunekawa Shin、Naruse Keiko、Nakamura Nobuhisa、Motegi Mikio、Nakai‐Shimoda Hiromi、Asano Saeko、Kato Makoto、Yamada Yuichiro、Izumoto‐Akita Takako、Yamamoto Akihito、Himeno Tatsuhito、Kondo Masaki、Kato Yoshiro、Nakamura Jiro、Kamiya Hideki
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 11 Issue: 1 Pages: 28-38
- DOI
  10.1111/jdi.13085
- NAID
  120006980549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10121, KAKENHI-PROJECT-17H04404, KAKENHI-PROJECT-17K09851
[Journal Article] Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin2016
- Author(s)
  Iida A, Seino Y, Fukami A, Maekawa R, Yabe D, Shimizu S, Kinoshita K, Takagi Y, Izumoto T, Ogata H, Ishikawa K, Ozaki N, Tsunekawa S, Hamada Y, Oiso Y, Arima H, Hayashi Y
- Journal Title
  
  Diabetologia
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461338
[Journal Article] Long-Term Pancreatic Beta Cell Exposure to High Levels of Glucose but Not Palmitate Induces DNA Methylation within the Insulin Gene Promoter and Represses Transcriptional Activity.2015
- Author(s)
  Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, Uenishi E, Seino Y, Ozaki N, Sugimura Y, Hamada Y, Kuroda A, Shinjo K, Kondo Y, Oiso Y.
- Journal Title
  
  PLoS One
  
  Volume: 10(2) Issue: 2 Pages: e0115350-e0115350
- DOI
  10.1371/journal.pone.0115350
- NAID
  120006872353
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790920, KAKENHI-PROJECT-25290048, KAKENHI-PROJECT-26430136, KAKENHI-PROJECT-26640088
[Journal Article] Fructose induces GIP, GLP-1 and insulin secretion: role of KATP channels2015
- Author(s)
  Yusuke Seino, Hidetada Ogata, Ryuya Maekawa, Takako Izumoto, Atsushi Iida, Norio Harada, Takashi Miki, Susumu Seino, Nobuya Inagaki, Shin Tsunekawa, Yutaka Oiso, Yoji Hamada
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461338
[Journal Article] Fructose induces glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and insulin secretion: Role of adenosine triphosphate-sensitive K+ channels2015
- Author(s)
  Seino Y, Ogata H, Maekawa R, Izumoto T, Iida A, Harada N, Miki T, Seino S, Inagaki N, Tsunekawa S, Oiso Y, Hamada Y
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 5 Pages: 522-526
- DOI
  10.1111/jdi.12356
- NAID
  120005770745
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25461338, KAKENHI-PROJECT-25461344, KAKENHI-PROJECT-25293051
[Journal Article] KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state2014
- Author(s)
  Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y
- Journal Title
  
  J Endocrinol
  
  Volume: 222 Issue: 2 Pages: 191-200
- DOI
  10.1530/joe-14-0161
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24659451, KAKENHI-PUBLICLY-25122708, KAKENHI-PROJECT-25293051, KAKENHI-PROJECT-25461338, KAKENHI-PROJECT-25461344, KAKENHI-PROJECT-25670116
[Presentation] 血管新生に対するヒト乳歯歯髄幹細胞培養上清の効果の検討2020
- Author(s)
  加藤誠，恒川新，中村信久，井上利恵子，林優佑，三浦絵美梨，山田祐一郎，石川貴大，森下啓明，姫野龍仁，近藤正樹，加藤義郎，神谷英紀，成瀬桂子，中村二郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K08874
[Presentation] Conditioned medium from dental pulp stem cells directly activate endothelial cells to promote all process of angiogenesis2020
- Author(s)
  M. Kato, S. Tsunekawa, N. Nakamura, E. Miura-Yura, Y. Yamada, Y. Hayashi, Y. Morishita, T. Himeno, M. Kondo, Y. Kato, H. Kamiya, K. Naruse, J. Nakamura
- Organizer
  56th Annual meeting European Association for the Study of Diabetes(EASD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08874
[Presentation] ヒト乳歯歯髄幹細胞培養上清が血管新生に及ぼす効果の検討2020
- Author(s)
  加藤誠，恒川新，中村信久，井上利恵子，林優佑，三浦絵美梨，山田祐一郎，森下啓明，姫野龍仁，近藤正樹，加藤義郎，神谷英紀，成瀬桂子，中村二郎
- Organizer
  第35回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-20K08874
[Presentation] Secreted Factors from Dental Pulp Stem Cells Ameliorated neural functions in Streptozotocin-Induced Diabetic Mice2019
- Author(s)
  EMIRI MIURA-YURA, SHIN TSUNEKAWA, KEIKO NARUSE, MIYUKA KAWAI, MAKOTO KATO, HIROMI SHIMODA, YUICHIRO YAMADA, MIKIO MOTEGI, SAEKO ASANO, TATSUHITO HIMENO, MASAKI KONDO, YOSHIRO KATO, JIRO NAKAMURA, HIDEKI KAMIYA
- Organizer
  The American Diabetes Association's 79th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09851
[Presentation] ヒト乳歯歯髄幹細胞培養上清が糖尿病性多発神経障害にもたらす効果の検討2019
- Author(s)
  三浦絵美梨、恒川新、成瀬桂子、茂木幹雄、浅野紗恵子、加藤誠、下田博美、山田祐一郎、姫野龍仁、近藤正樹、加藤義郎、神谷英紀、中村二郎
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09851
[Presentation] Secreted Factors from Dental Pulp Stem Cells Ameliorated Diabetic Polyneuropathy in Streptozotocin-Induced Diabetic Mice2018
- Author(s)
  Emiri Miura-Yura, Shin Tsunekawa, Tatsuhito Himeno, Keiko Naruse, Mikio Motegi, Hiromi Shimoda, Makoto Kato, Yuichiro Yamada, Masaki Kondo, Yoshiro Kato, Hideki Kamiya and Jiro Nakamura
- Organizer
  78th American Diabetes Association Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09851
[Presentation] ヒト乳歯歯髄幹細胞培養上清が糖尿病多発神経障害にもたらす効果の検討2018
- Author(s)
  三浦絵美梨、恒川新、成瀬桂子、姫野龍仁、近藤正樹、加藤義郎、神谷英紀、中村二郎
- Organizer
  第61回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-17K09851
[Presentation] Secreted Factors from Dental Pulp Stem Cells Ameliorated Diabetic Polyneuropathy in Streptozotocin-Induced Diabetic Mice2018
- Author(s)
  EMIRI MIURA-YURA, SHIN TSUNEKAWA, TATSUHITO HIMENO, KEIKO NARUSE, MIKIO MOTEGI, HIROMI SHIMODA, MAKOTO KATO, YUICHIRO YAMADA, MASAKI KONDO, YOSHIRO KATO, HIDEKI KAMIYA, JIRO NAKAMURA
- Organizer
  The American Diabetes Association's 78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09851
[Presentation] ヒト乳歯歯髄幹細胞培養上清が糖尿病多発神経障害にもたらす効果の検討2018
- Author(s)
  三浦絵美梨、恒川新、成瀬桂子、姫野龍仁、近藤正樹、加藤義郎、神谷英紀、中村二郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09851
[Presentation] 高炭水化物食の慢性摂取におけるGIP分泌と作用に対する検討2016
- Author(s)
  前川　龍也、清野　祐介、尾方　秀忠、飯田　淳史、村瀬　正敏、城尾恵里奈、鈴木　和代、原田　範雄、細川　香里、丹羽　靖浩、泉本　貴子、恒川　　新、濱田　洋司、林　　良敬、稲垣　暢也、有馬　　寛
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  (国立京都国際会館）京都府京都市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] 高炭水化物食の慢性摂取はGIPとインスリン分泌増加を伴い体重増加を来す2016
- Author(s)
  前川龍也　清野祐介　尾方秀忠　飯田淳史　村瀬正敏　城尾恵里奈　鈴木和代　原田範雄　細川香里　丹羽靖浩　泉本貴子　恒川　新　濱田洋司　林　良敬 稲垣暢也　有馬　寛
- Organizer
  第３０回日本糖尿病・肥満動物学会　年次学術集会
- Place of Presentation
  （パシフィッコ横浜）神奈川県横浜市
- Year and Date
  2016-01-10
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] DPP-4阻害薬は、グルカゴン欠損下では膵β細胞傷害時においても、GIPによるインスリン分泌増強を介して耐糖能を改善させる2016
- Author(s)
  飯田淳史、清野祐介、前川龍也、村瀬正敏、矢部大介、清水忍、秋田貴子、恒川新、濱田洋司、林良敬、有馬寛
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  (国立京都国際会館）京都府京都市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] GIPはグルカゴン遺伝子欠損マウスにおいて膵β細胞傷害時の血糖値改善に関与する2015
- Author(s)
  飯田　淳史、清野　祐介、前川　龍也、丹羽　靖浩、細川　香里、泉本　貴子、木下　佳大、高木　祐輔、尾方　秀忠、尾崎　信暁、恒川　新、濱田　洋司、林　良敬、大磯　ユタカ
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  (グランプラス　セント・ヴァレンタイン）山口県下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] Glucose-induced glucose-dependent insulinotropic polypeptide (GIP) secretion in vivo: Role of ATP-sensitive K+ (KATP) channels2015
- Author(s)
  Ryuya Maekawa, Yusuke Seino, Hidetada Ogata, Norio Harada, Kazuyo Suzuki, Erina Joo, Atsushi Iida, Yasuhiro Niwa, Kaori Hosokawa,Takako Izumoto, Susumu Seino, Yoshitaka Hayashi, Nobuya Inagaki, Shin Tsunekawa, Yoji Hamada, Yutaka Oiso
- Organizer
  incretin 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] Glucose-dependent insulinotropic polypeptide (GIP) preserves insulin secretion and contributes to good-glycemic control in proglucagon-deficient mice treated with streptozotocin2015
- Author(s)
  Yusuke Seino, Atsushi Iida, Ayako Fukami, Ryuya Maekawa, Takako Izumoto, Nobuaki Ozaki, Shin Tsunekawa, Yoji Hamada, Yoshitaka Hayashi, Yutaka Oiso
- Organizer
  incretin 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] 高炭水化物を用いたGIP分泌とその作用に関する検討2015
- Author(s)
  前川　龍也、尾方　秀忠、清野　祐介、飯田　淳史、鈴木　和代、原田　範雄、丹羽　靖浩、細川　香里、泉本　貴子、石川　孝太、稲垣　暢也、恒川　新、濱田　洋司、大磯　ユタカ
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  (グランプラス　セント・ヴァレンタイン）山口県下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] 高炭水化物食を用いたGIP分泌とその作用に関する検討2015
- Author(s)
  前川　龍也、尾方　秀忠、清野　祐介、飯田　淳史、鈴木　和代、原田　範雄、丹羽　靖浩、細川　香里、泉本　貴子、石川　孝太、稲垣　暢也、恒川　新、濱田　洋司、大磯　ユタカ
- Organizer
  第５８回日本糖尿病学会学術集会
- Place of Presentation
  グランプラス　セント・ヴァレンタイン　(山口県下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] Role of the KATP channel in glucose-induced GIP secretion2014
- Author(s)
  Yusuke Seino, Hidetada Ogata, Ryuya Maekawa, Yasuhiro Niwa, Kaori Hosokawa, Atsushi Iida, Takako Izumoto, Shin Tsunekawa, Yoji Hamada, Susumu Seino, Yutaka Oiso
- Organizer
  10th IDF-WPR CONGRESS 2014 6th AASD Scientific Meeting
- Place of Presentation
  Ｓｉｎｇａｐｏｒｅ (Ｓｉｎｇａｐｏｒｅ)
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] 単糖類はKATPチャネル依存性の経路と非依存性の経路によりGIP分泌を惹起する2014
- Author(s)
  尾方　秀忠、清野　祐介、原田　範雄、飯田　淳史、鈴木　和代、泉本　貴子、石川　孝太、上西　栄太、尾崎　信暁、林　良敬、三木　隆司、稲垣　暢也、清野　祐介、濱田　洋司、恒川　新、大磯　ユタカ
- Organizer
  第５７回日本糖尿病学会学術集会
- Place of Presentation
  大阪国際会議場 (大阪府大阪市）
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25461338
[Presentation] 膵β細胞における過剰栄養によるエピゲノム修飾の検討2013
- Author(s)
  石川孝太、恒川新、清野祐介、上西栄太、泉本貴子、飯田淳史、尾方秀忠、藤谷淳、大川哲司、濱田洋司、大磯ユタカ
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本 (熊本市）
- Data Source
  KAKENHI-PROJECT-24790920
[Presentation] Over-nutrition Increased DNA Methylation of Insulin Gene Promoter in Pancreatic Beta-Cells2013
- Author(s)
  Kota Ishikawa, Shin Tsunekawa, Takako Izumoto, Atsushi Iida, Hidetada Ogata, Tetsuji Okawa, Atsushi Fujiya, Eita Uenishi, Yusuke Seino, Yoji Hamada, Yutaka Oiso
- Organizer
  America Diabetes Association 73rd Scientific Sessions
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24790920
[Presentation] 長期の高ショ糖食と高スターチ食はそれぞれGIP分泌増強をもたらすが、異なる体重の変化をきたす
- Author(s)
  尾方　秀忠、清野　祐介、恒川　新、原田　範雄、三浦　英里子、池庭　誠、細川　香里、泉本　貴子、飯田　淳史、石川　孝太、藤谷　淳、大川　哲司、上西　栄太、深見　亜也子、尾崎　信暁、三木　隆司、清野　進、稲垣　暢也、濱田　洋司、大磯　ユタカ
- Organizer
  第17回日本病態栄養学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪市)
- Data Source
  KAKENHI-PROJECT-25461338

1. Hideki Kamiya (70542679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. Yusuke Seino (80534833)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. HAMADA Yoji (20293706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
4. OISO Yutaka (40203707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. 山本朗仁 (50244083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 近藤正樹 (00717910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 姫野龍仁 (60753762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 石山宏平 (50437589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 岩崎研太 (10508881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 成瀬桂子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 清野進

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Tsunekawa Shin 恒川 新

TSUNEKAWA Shin 恒川 新

Research Projects

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ヒト乳歯歯髄幹細胞を用いた膵島オルガノイドによる画期的膵島移植プロトコールの開発

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自己免疫性モノアミン合成障害による新規低血圧疾患概念の確立Principal Investigator

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Development of Novel Therapies for Diabetic Ischemic Diseases using Secreted Factors from Stem Cells

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Development of the new treatment for diabetic neuropathy using somatic stem cells and their secreted factors

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The co-transplantation of Islets with Dental Pulp Stem Cells Improved Survival and Function of Transplanted Beta-CellsPrincipal Investigator

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Role of the KATP channel in enteroendocrine cells and absorptive epithelial cells

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Long-Term Pancreatic Beta Cell Exposure To High Levels of Glucose but not Palmitate induces DNA Methylation within the Insulin Gene Promoter and represses Transcriptional ActivityPrincipal Investigator

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[Journal Article] Secreted factors from stem cells of human exfoliated deciduous teeth directly activate endothelial cells to promote all processes of angiogenesis2020

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[Journal Article] Secreted factors from cultured dental pulp stem cells promoted neurite outgrowth of dorsal root ganglion neurons and ameliorated neural functions in streptozotocin‐induced diabetic mice2019

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[Journal Article] Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin2016

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[Journal Article] Long-Term Pancreatic Beta Cell Exposure to High Levels of Glucose but Not Palmitate Induces DNA Methylation within the Insulin Gene Promoter and Represses Transcriptional Activity.2015

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[Journal Article] Fructose induces GIP, GLP-1 and insulin secretion: role of KATP channels2015

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[Journal Article] Fructose induces glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and insulin secretion: Role of adenosine triphosphate-sensitive K+ channels2015

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[Journal Article] KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state2014

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Tsunekawa Shin 恒川新

TSUNEKAWA Shin 恒川新

[Presentation] 高炭水化物食の慢性摂取はGIPとインスリン分泌増加を伴い体重増加を来す2016