Hashimoto Yoshihide 橋本良秀

Researcher Number	40638384
Other IDs	https://orcid.org/0000-0003-0537-8291
Affiliation *help	2015 – 2018 : 東京医科歯科大学, 生体材料工学研究所, 助教 2015 : 東京医科歯科大学, 生体材料工学研究所生体機能修復研究部門, 物質医工学分野助教 2014 : 東京医科歯科大学, 生体材料工学研究所, 寄附研究部門助教
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Dental engineering/Regenerative dentistry / Biomedical engineering/Biomaterial science and engineering / Structural/Functional materials
Keywords	Principal Investigator ナノゲル / エキソソーム / 組織工学 / マイクロ加工 / 成長因子 / 脱細胞化組織 / 細胞微小環境 / 心筋梗塞治療 / グリコサミノグリカン / 心筋修復 … More Except Principal Investigator 再生医療 / 組織再構築 / バイオマテリアル / 骨再生 / 神経組織再生 / 硬組織再生 / collagen / GBR / 分子シャペロン機能 / Guided Bone Regeneration / 生体材料 / ドラッグデリバリーシステム(DDS) / membrane / 微細構造 / 脱細胞化生体組織 / nano gel / 国際情報交換 / 反応性スパッタ / 骨組織再生 / 軟組織再生 / メンブレン / 酸化チタン薄膜 / 抗血栓性 / Nanogel / ナノキャリアー Less

反応性スパッタによるチタン製循環器用材料の開発と抗血栓性発現メカニズムの解明Ongoing
- Principal Investigator
  
  大家渓
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural/Functional materials
- Research Institution
  Seikei University
脱細胞化生体組織を規範とするTissueoid(人工生体組織）の創製Ongoing
- Principal Investigator
  
  岸田晶夫
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical and Dental University
脱細胞化組織を基盤とするソフトナノ粒子複合材料の開発と心筋梗塞治療への応用Principal InvestigatorOngoing
- Principal Investigator
  
  橋本良秀
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical and Dental University
Neuroregeneration by concerted regulation of cellular microenvironmentsPrincipal Investigator
- Principal Investigator
  
  Hashimoto Yoshihide
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical and Dental University
Analysis on the possibility of various tissue regeneration with the Nanogel possesing a molecular chaperone function
- Principal Investigator
  
  Miyahara Takayuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Tokyo Medical and Dental University

All 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Nanogel-integrated pH responsive composite hydrogels for controlled drug delivery2017
- Author(s)
  G. E. Cinay, M. Alipour, Y. Hashimoto, Y. Sasaki, K. Akiyoshi, S. Kizilel
- Journal Title
  
  ACS Biomater Sci Eng
  
  Volume : 3 Pages : 370-380
- DOI
  10.1021/acsbiomaterials.6b00670
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01387
[Journal Article] Histological structure affects recellularization of decellularized arteries2017
- Author(s)
  J. Negishi, Y. Hashimoto, A. Yamashita, T. Kimura, A. Kishida, S. Funamoto
- Journal Title
  
  Mater Sci Eng C-Mater Biol Appl
  
  Volume : 70 Pages : 450-455
- DOI
  10.1016/j.msec.2016.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01387
[Journal Article] Effects of a polysaccharide nanogel-crosslinked membraneon wound healing2017
- Author(s)
  Maeda H, Kobayashi H, Miyahara T, Hashimoto Y, Akiyoshi K, Kasugai S.
- Journal Title
  
  Jouranal of Biomedical Materials research Part B Applied Materials
  
  Volume : 105 Pages : 554-560
- DOI
  10.1002/jbm.b.33571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870177, KAKENHI-PROJECT-26893073, KAKENHI-PROJECT-26750156
[Journal Article] Advanced artificial extracellular matrices using amphiphilic nanogel-cross-linked thin films to anchor adhesion proteins and cytokines2016
- Author(s)
  Y. Hashimoto, S. Mukai, S. Sawada, T. Sasaki, K. Akiyoshi
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume : 2 Pages : 375-384
- DOI
  10.1021/acsbiomaterials.5b00485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26750156
[Journal Article] Nanogel tectonic porous gel loading biologics, nanocarriers, and cells for advanced scaffold2015
- Author(s)
  Y. Hashimoto, S. Mukai,S. Sawada, Y. Sasaki, K. Akiyoshi
- Journal Title
  
  Biomaterials
  
  Volume : 37 Pages : 107-115
- DOI
  10.1016/j.biomaterials.2014.10.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23681021, KAKENHI-PROJECT-26750156
[Journal Article] Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis.2014
- Author(s)
  M. Yokota, Y. Kobayashi, J. Morita, H. Suzuki, Y. Hashimoto, Y. Sasaki, K. Akiyoshi, K. Moriyama
- Journal Title
  
  Plos One
  
  Volume : 9
- DOI
  10.1371/journal.pone.0101693
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22114009, KAKENHI-PROJECT-23681021, KAKENHI-PROJECT-25463168, KAKENHI-PROJECT-26750156
[Journal Article] Cycloamylose-nanogel drug delivery system-mediated intratumor silencing of the vascular endothelial growth factor regulates neovascularization in tumor microenvironment2014
- Author(s)
  H. Fujii, M. Shin-Ya, S. Takeda, Y. Hashimoto, S. Mukai, S. Sawada, T. Adachi, K. Akiyoshi, T. Miki, O. Mazda
- Journal Title
  
  Cancer Sci
  
  Volume : 105 Pages : 1616-1625
- DOI
  10.1111/cas.12547
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22114009, KAKENHI-PROJECT-26670452, KAKENHI-PROJECT-26750156, KAKENHI-PROJECT-26861741
[Presentation] 有機-無機ハイブリッドポーラス材料の設計と再生医療応用2015
- Author(s)
  藤原理絵, 橋本良秀, 丸川恵理子, 澤田晋一, 向井貞篤, 佐々木善浩, 秋吉一成
- Organizer
  第37回日本バイオマテリアル学会大会
- Place of Presentation
  京都テルサ（京都府, 京都市）
- Year and Date
  2015-11-09
- Data Source
  KAKENHI-PROJECT-26750156
[Presentation] 有機-無機ハイブリッドポーラス材料の設計と医療応用2015
- Author(s)
  藤原理絵, 橋本良秀, 丸川恵理子, 澤田晋一, 向井貞篤, 佐々木善浩, 秋吉一成
- Organizer
  第64回高分子討論会
- Place of Presentation
  東北大学川内キャンパス（宮城県, 仙台市）
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-26750156
[Presentation] ナノゲルテクトニクス材料：ナノゲル架橋ハイブリッドフィルムの創製と機能評価2015
- Author(s)
  向井貞篤, 橋本良秀, 田原義朗, 澤田晋一, 秋吉一成
- Organizer
  第64回高分子学会年次大会
- Place of Presentation
  札幌コンベンションセンター（北海道, 札幌市）
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-26750156
[Presentation] 多糖ナノボールの集積制御に基づく新規ゲル材料の設計とバイオマテリアル応用2015
- Author(s)
  沖田圭司, 竹田茂生, 橋本良秀, 向井貞篤, 澤田晋一, 佐々木善浩, 秋吉一成
- Organizer
  第64回高分子学会年次大会
- Place of Presentation
  札幌コンベンションセンター（北海道, 札幌市）
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-26750156
[Presentation] Fabrication of nanogel-crosslinked porous gels for tissue engineering applications
- Author(s)
  Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Kazunari Akiyoshi
- Organizer
  The 41st Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Chicago, USA
- Year and Date
  2014-07-13 – 2014-07-16
- Data Source
  KAKENHI-PROJECT-26750156
[Presentation] 多孔質構造を有するナノゲル架橋ハイブリッドゲルの開発と機能評価
- Author(s)
  橋本良秀、向井貞篤、澤田晋一、秋吉一成
- Organizer
  第63回高分子討論会
- Place of Presentation
  長崎
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26750156

1. Miyahara Takayuki (30735246)

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# of Collaborated Products : 1results
2. KASUGAI Shohei (70161049)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
3. SHIOTA Makoto (90196353)

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# of Collaborated Products : 0results
4. TACHIKAWA Noriko (70236537)

# of Collaborated Projects : 1results

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5. KURODA Shinji (50323689)

# of Collaborated Projects : 1results

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6. NAKATA Hidemi (30451967)

# of Collaborated Projects : 1results

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7. AKIYOSHI Kazunari (90201285)

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
8. SHIMODA Asako (90712042)

# of Collaborated Projects : 1results

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9. 大家渓 (50549962)

# of Collaborated Projects : 1results

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10. 岩森暁 (90345603)

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11. 岸田晶夫 (60224929)

# of Collaborated Projects : 1results

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12. 木村剛 (10393216)

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13. 中村奈緒子 (70754878)

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14. 舩本誠一 (40609947)

# of Collaborated Projects : 1results

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15. 根岸淳 (60722634)

# of Collaborated Projects : 1results

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16. SHINYA Masaharu

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
17. 佐々木善浩

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
18. 森山啓司

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
19. 小林起穂

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
20. 松田修

# of Collaborated Projects : 0results

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21. 澤田晋一

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
22. 足立哲也

# of Collaborated Projects : 0results

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23. 小林裕史

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

Hashimoto Yoshihide 橋本 良秀

Research Projects

Research Products

Co-Researchers

反応性スパッタによるチタン製循環器用材料の開発と抗血栓性発現メカニズムの解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脱細胞化生体組織を規範とするTissueoid(人工生体組織）の創製Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脱細胞化組織を基盤とするソフトナノ粒子複合材料の開発と心筋梗塞治療への応用Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neuroregeneration by concerted regulation of cellular microenvironmentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on the possibility of various tissue regeneration with the Nanogel possesing a molecular chaperone function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nanogel-integrated pH responsive composite hydrogels for controlled drug delivery2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histological structure affects recellularization of decellularized arteries2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of a polysaccharide nanogel-crosslinked membraneon wound healing2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Advanced artificial extracellular matrices using amphiphilic nanogel-cross-linked thin films to anchor adhesion proteins and cytokines2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nanogel tectonic porous gel loading biologics, nanocarriers, and cells for advanced scaffold2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cycloamylose-nanogel drug delivery system-mediated intratumor silencing of the vascular endothelial growth factor regulates neovascularization in tumor microenvironment2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 有機-無機ハイブリッドポーラス材料の設計と再生医療応用2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 有機-無機ハイブリッドポーラス材料の設計と医療応用2015

Author(s)

Organizer

Place of Presentation

Year and Date

Hashimoto Yoshihide 橋本良秀

[Presentation] ナノゲルテクトニクス材料：ナノゲル架橋ハイブリッドフィルムの創製と機能評価2015