Shimoda Asako 下田麻子

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SHIMODA Asako 下田麻子

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Researcher Number	90712042
Other IDs
Affiliation (Current)	2025: 京都大学, 白眉センター, 特定助教
Affiliation (based on the past Project Information) *help	2023: 京都大学, 医学研究科, 特定研究員 2020 – 2022: 京都大学, 工学研究科, 特定研究員 2016 – 2018: 京都大学, 工学研究科, 特定研究員 2015: 京都大学, 工学(系)研究科(研究院), 研究員 2015: 京都大学, 工学研究科高分子化学専攻
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Basic Section 90120:Biomaterials-related Except Principal Investigator Dental engineering/Regenerative dentistry
Keywords	Principal Investigator 糖鎖 / レクチンアレイ / エクソソーム / 基質小胞 / レクチンマイクロアレイ / 糖鎖解析 / 細胞外小胞 / 細胞外微粒子 / 生体材料 / 骨再生 / 間葉系幹細胞 / マトリックスベシクル … More Except Principal Investigator … More 国際情報交換 / Guided Bone Regeneration / 神経組織再生 / 骨組織再生 / 分子シャペロン機能 / ナノキャリアー / ドラッグデリバリーシステム(DDS) / 硬組織再生 / 軟組織再生 / メンブレン / 再生医療 / nano gel / collagen / membrane / Nanogel / GBR / 骨再生 Less

Classification of osteoblast-derived extracellular vesicles by glycans and cellular responsesPrincipal Investigator
- Principal Investigator
  
  Shimoda Asako
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kyoto University
Elucidation of the interaction of exosome surface glycans and target cellsPrincipal Investigator
- Principal Investigator
  
  Shimoda Asako
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kyoto University
MSC exosome-polysaccharide nanogel hybrid for bone regenerationPrincipal Investigator
- Principal Investigator
  
  Shimoda Asako
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kyoto University
Analysis on the possibility of various tissue regeneration with the Nanogel possesing a molecular chaperone function
- Principal Investigator
  
  Miyahara Takayuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Tokyo Medical and Dental University

All 2023 2022 2021 2020 2018 2017 2016 2015

All Journal Article Presentation Book Patent

[Book] 医療を変えるエクソソーム生体機能から疾患メカニズム，臨床応用まで2018
- Author(s)
  下田麻子、秋吉一成
- Total Pages
  240
- Publisher
  化学同人
- ISBN
  9784759819786
- Data Source
  KAKENHI-PROJECT-17K13029
[Book] 炎症と免疫2018
- Author(s)
  下田麻子、秋吉一成
- Total Pages
  88
- Publisher
  先端医学社
- ISBN
  9784865503463
- Data Source
  KAKENHI-PROJECT-17K13029
[Book] パラダイムシフトをもたらすエクソソーム機能研究最前線　－シグナル伝達からがん、免疫、神経疾患との関わり、創薬利用まで2017
- Author(s)
  下田麻子、秋吉一成
- Total Pages
  314
- Publisher
  (株)エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-15K16332
[Book] 細胞、特集エクソソームと疾患－そして臨床応用へ－2016
- Author(s)
  下田麻子、秋吉一成
- Total Pages
  52
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-15K16332
[Book] 膜 (Membrane )　第40巻5号、特集生体膜シンポジウム「細胞外ベシクル・エクソソーム研究の最前線」2015
- Author(s)
  澤田晋一，下田麻子、佐藤祐子，瀬尾尚宏、珠玖洋、秋吉一成
- Total Pages
  82
- Publisher
  日本膜学会
- Data Source
  KAKENHI-PROJECT-15K16332
[Journal Article] Surface Glycan Profiling of Extracellular Vesicles by Lectin Microarray and Glycoengineering for Control of Cellular Interactions2023
- Author(s)
  Shimoda Asako、Akiyoshi Kazunari
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 40 Issue: 4 Pages: 795-800
- DOI
  10.1007/s11095-023-03511-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12645, KAKENHI-PLANNED-23H04934, KAKENHI-PROJECT-22H00585
[Journal Article] Diversity analysis of exosomes by their glycan profiling for controlling cellular interactions2023
- Author(s)
  下田麻子、舘野浩章、秋吉一成
- Journal Title
  
  生化学
  
  Volume: 95 Issue: 2 Pages: 136-143
- DOI
  10.14952/SEIKAGAKU.2023.950136
- ISSN
  0037-1017
- Year and Date
  2023-04-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12645
[Journal Article] Classification of Extracellular Vesicles Based on Surface Glycan Structures by Spongy-like Separation Media2022
- Author(s)
  Kanao Eisuke、Wada Shuntaro、Nishida Hiroshi、Kubo Takuya、Tanigawa Tetsuya、Imami Koshi、Shimoda Asako、Umezaki Kaori、Sasaki Yoshihiro、Akiyoshi Kazunari、Adachi Jun、Otsuka Koji、Ishihama Yasushi
- Journal Title
  
  Analytical Chemistry
  
  Volume: 94 Issue: 51 Pages: 18025-18033
- DOI
  10.1021/acs.analchem.2c04391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12645, KAKENHI-PROJECT-21J15131, KAKENHI-PROJECT-20K20567, KAKENHI-PROJECT-21K14652
[Journal Article] Distinguishing Functional Exosomes and Other DNA-containing Extracellular Vesicles Based on the Difference in Strength of Negative Membrane Charge2022
- Author(s)
  Seo, Naohiro; Nakamura, Junko; Kaneda, Tsuguhiro; Tateno, Hiroaki; Shimoda, Asako; Ichiki, Takanori; Furukawa, Koichi; Hirabayashi, Jun; Kazunari, Akiyoshi; Shiku, Hiroshi
- Journal Title
  
  J. Extracell. Vesicles
  
  Volume: 11 Issue: 3 Pages: 12205-12205
- DOI
  10.1002/jev2.12205
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02628, KAKENHI-PROJECT-20K12645, KAKENHI-PROJECT-19K22518
[Journal Article] CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma2022
- Author(s)
  Odaka Haruki、Hiemori Keiko、Shimoda Asako、Akiyoshi Kazunari、Tateno Hiroaki
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 22 Issue: 1 Pages: 153-153
- DOI
  10.1186/s12876-022-02228-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12645, KAKENHI-PROJECT-19K16263, KAKENHI-PROJECT-22H00585
[Journal Article] New Lipophilic Fluorescent Dyes for Labeling Extracellular Vesicles: Characterization and Monitoring of Cellular Uptake2021
- Author(s)
  Shimomura T, Seino R, Umezaki K, Shimoda A, Ezoe T, Ishiyama M, Akiyoshi K.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 32 Issue: 4 Pages: 680-684
- DOI
  10.1021/acs.bioconjchem.1c00068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12645
[Journal Article] Assessment of Surface Glycan Diversity on Extracellular Vesicles by Lectin Microarray and Glycoengineering Strategies for Drug Delivery Applications2021
- Author(s)
  Shimoda Asako、Miura Risako、Tateno Hiroaki、Seo Naohiro、Shiku Hiroshi、Sawada Shin‐ichi、Sasaki Yoshihiro、Akiyoshi Kazunari
- Journal Title
  
  Small Methods
  
  Volume: 6 Issue: 2 Pages: 2100785-2100785
- DOI
  10.1002/smtd.202100785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12645, KAKENHI-PROJECT-22H00585
[Journal Article] Glycomics of extracellular vesicles, exosomes2020
- Author(s)
  下田麻子、秋吉一成
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 3 Pages: 336-342
- DOI
  10.14952/SEIKAGAKU.2020.920336
- ISSN
  0037-1017
- Year and Date
  2020-06-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12645
[Journal Article] Glycan profiling analysis using evanescent-field fluorescence-assisted lectin array: Importance of sugar recognition for cellular uptake of exosomes from mesenchymal stem cells2017
- Author(s)
  Shimoda Asako、Tahara Yoshiro、Sawada Shin-ichi、Sasaki Yoshihiro、Akiyoshi Kazunari
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 491 Issue: 3 Pages: 701-707
- DOI
  10.1016/j.bbrc.2017.07.126
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K13029, KAKENHI-PROJECT-16H03842
[Journal Article] Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA2016
- Author(s)
  Shimoda A, Ueda K, Nishiumi S, Murata-Kamiya N, Mukai SA, Sawada S, Azuma T, Hatakeyama M, Akiyoshi K
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 18346-18346
- DOI
  10.1038/srep18346
- NAID
  120005689168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K16332, KAKENHI-ORGANIZER-22114001, KAKENHI-PROJECT-25250016, KAKENHI-PROJECT-25305027, KAKENHI-PROJECT-16H06373, KAKENHI-PROJECT-26710007, KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-16K15273
[Patent] 多能性幹細胞を骨芽細胞へと分化誘導することにより得られうる細胞集団から骨芽細胞を検出する方法、及びその方法のために用いられるキット2018
- Inventor(s)
  秋吉一成、下田麻子
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-043297
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K13029
[Presentation] 細胞外小胞の表層糖鎖プロファイリングによる多様性評価2022
- Author(s)
  下田麻子、澤田晋一、佐々木善浩、秋吉一成
- Organizer
  第9回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20K12645
[Presentation] 細胞外小胞の表層糖鎖プロファイリングと機能2022
- Author(s)
  下田麻子
- Organizer
  第32回フォーラム・イン・ドージン生命現象に関わる細胞外小胞体の多彩な役割－ヴェールを脱ぐエクソソーム－
- Invited
- Data Source
  KAKENHI-PROJECT-20K12645
[Presentation] Analysis of heterogeneity of surface glycans on extracellular vesicles by lectin array2021
- Author(s)
  Asako Shimoda, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
- Organizer
  Pacifichem2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12645
[Presentation] Analysis of surface glycans on extracellular vesicles using lectin array and roles of their glycans in cellular recognition2018
- Author(s)
  Asako Shimoda, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
- Organizer
  ISEV2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13029
[Presentation] 間葉系幹細胞エクソソームのレクチンアレイ糖鎖解析と細胞相互作用機序2017
- Author(s)
  下田麻子、田原義朗、澤田晋一、佐々木善浩、秋吉一成
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K13029
[Presentation] Glycan profiling analysis of extracellular vesicles from mesenchymal stem cells (MSCs) and osteogenic MSCs2017
- Author(s)
  Asako Shimoda, Kazunari Akiyoshi
- Organizer
  ISEV2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13029
[Presentation] レクチンマイクロアレイによるエクソソーム表面糖鎖の解析2017
- Author(s)
  下田麻子、田原義朗、澤田晋一、佐々木善浩、秋吉一成
- Organizer
  第9回日本RNAi研究会/第4回細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-17K13029
[Presentation] レクチンアレイによるエクソソーム表面糖鎖解析と細胞応答2017
- Author(s)
  下田麻子、秋吉一成
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-17K13029
[Presentation] 間葉系幹細胞由来エクソソームを用いた骨再生システムの構築2017
- Author(s)
  下田麻子、秋吉一成
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2017-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K16332
[Presentation] 骨芽細胞へ分化誘導した間葉系幹細胞由来exosomeの機能評価2016
- Author(s)
  下田麻子、澤田晋一、秋吉一成
- Organizer
  第8回日本RNAi研究会/第3回細胞外小胞学会
- Place of Presentation
  グランドプリンスホテル広島（広島県・広島市）
- Year and Date
  2016-08-31
- Data Source
  KAKENHI-PROJECT-15K16332
[Presentation] Helicobacter pylori virulence factor CagA is delivered by exosome through the bloodstream2016
- Author(s)
  A. Shimoda, K. Ueda, S. Nishiumi, N. Murata-Kamiya, M. Hatakeyama, K. Akiyoshi
- Organizer
  ASEMV 2016
- Place of Presentation
  Pacific Grove (USA)
- Year and Date
  2016-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16332
[Presentation] ExosomeによるHelicobacter pylori CagAタンパク質デリバリー2015
- Author(s)
  下田麻子、植田幸嗣、西海信、紙谷尚子、向井貞篤、澤田晋一、東健、畠山昌則、秋吉一成
- Organizer
  第７回日本RNAi研究会/第２回細胞外小胞学会
- Place of Presentation
  グランドプリンスホテル広島（広島県、広島市）
- Year and Date
  2015-08-26
- Data Source
  KAKENHI-PROJECT-15K16332
[Presentation] Isolation and Characterization of Helicobacter pylori CagA protein-containing exosome2015
- Author(s)
  A. Shimoda, S. Mukai, S. Sawada, N. Murata-Kamiya, M. Hatakeyama, K. Akiyoshi
- Organizer
  ISEV 2015 Annual Meeting
- Place of Presentation
  Washington DC (USA)
- Year and Date
  2015-04-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16332
[Presentation] Helicobacter pylori CagA含有Exosomeの単離と機能2015
- Author(s)
  下田麻子、向井貞篤、澤田晋一、紙谷尚子、畠山昌則、秋吉一成
- Organizer
  第31回 DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都、新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K16332

1. Miyahara Takayuki (30735246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KASUGAI Shohei (70161049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SHIOTA Makoto (90196353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TACHIKAWA Noriko (70236537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KURODA Shinji (50323689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKATA Hidemi (30451967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. AKIYOSHI Kazunari (90201285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HASHIMOTO Yoshihide (40638384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 古川鋼一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 古川圭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimoda Asako 下田 麻子

SHIMODA Asako 下田 麻子

Research Projects

Research Products

Co-Researchers

Classification of osteoblast-derived extracellular vesicles by glycans and cellular responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the interaction of exosome surface glycans and target cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MSC exosome-polysaccharide nanogel hybrid for bone regenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on the possibility of various tissue regeneration with the Nanogel possesing a molecular chaperone function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 医療を変えるエクソソーム 生体機能から疾患メカニズム，臨床応用まで2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 炎症と免疫2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] パラダイムシフトをもたらすエクソソーム機能研究最前線 －シグナル伝達からがん、免疫、神経疾患との関わり、創薬利用まで2017

Author(s)

Total Pages

Publisher

Data Source

[Book] 細胞、特 集 エクソソームと疾患 －そして臨床応用へ－2016

Author(s)

Total Pages

Publisher

Data Source

[Book] 膜 (Membrane ) 第40巻5号、特集 生体膜シンポジウム「細胞外ベシクル・エクソソーム研究の最前線」2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Surface Glycan Profiling of Extracellular Vesicles by Lectin Microarray and Glycoengineering for Control of Cellular Interactions2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diversity analysis of exosomes by their glycan profiling for controlling cellular interactions2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Classification of Extracellular Vesicles Based on Surface Glycan Structures by Spongy-like Separation Media2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinguishing Functional Exosomes and Other DNA-containing Extracellular Vesicles Based on the Difference in Strength of Negative Membrane Charge2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma2022

Shimoda Asako 下田麻子

SHIMODA Asako 下田麻子

[Book] 医療を変えるエクソソーム生体機能から疾患メカニズム，臨床応用まで2018

[Book] パラダイムシフトをもたらすエクソソーム機能研究最前線　－シグナル伝達からがん、免疫、神経疾患との関わり、創薬利用まで2017

[Book] 細胞、特集エクソソームと疾患－そして臨床応用へ－2016

[Book] 膜 (Membrane )　第40巻5号、特集生体膜シンポジウム「細胞外ベシクル・エクソソーム研究の最前線」2015

[Patent] 多能性幹細胞を骨芽細胞へと分化誘導することにより得られうる細胞集団から骨芽細胞を検出する方法、及びその方法のために用いられるキット2018