Kubo Masayuki 久保政之

… Alternative Names

久保政之クボマサユキ

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Researcher Number	40646080
Other IDs
Affiliation (Current)	2026: 奈良県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 奈良県立医科大学, 医学部附属病院, 研究員
Review Section/Research Field	Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Except Principal Investigator 動物疾患モデル / 動物モデル / 血栓性血小板減少性紫斑病

Development of an animal model of acquired thrombotic thrombocytopenic purpura
- Principal Investigator
  
  Matsumoto Masanori
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nara Medical University

All 2025 2024 2023 2022

All Journal Article Presentation

[Journal Article] A novel automated chemiluminescent enzyme immunoassay for ADAMTS-13 activity enables accompanying measurements of the inhibitory autoantibodies2025
- Author(s)
  Kubo Masayuki、Konko Kazuyasu、Kinoshita Emi、Uemae Satoshi、Kobayashi Katsushi、Hayashi Yoshinori、Kan Akihiko、Fujimura Yoshihiro、Matsumoto Masanori
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 23 Issue: 3 Pages: 957-967
- DOI
  10.1016/j.jtha.2024.11.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08461
[Journal Article] Persistent ADAMTS13 Inhibitor Delays Recovery of ADAMTS13 activity in Caplacizumab-Treated Japanese iTTP Patients2024
- Author(s)
  Saito Kenki、Sakai Kazuya、Kubo Masayuki、Azumi Hidekazu、Hamamura Atsushi、Ochi Shinichi、Amagase Hiroki、Kunieda Hisako、Ogawa Yoshiyuki、Yagi Hideo、Matsumoto Masanori
- Journal Title
  
  Blood Advances
  
  Volume: 2024 Issue: 9 Pages: 2151-2159
- DOI
  10.1182/bloodadvances.2023012451
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K25186, KAKENHI-PROJECT-22K08461
[Journal Article] von Willebrand factor Ristocetin co-factor activity to von Willebrand factor antigen level ratio for diagnosis of acquired von Willebrand syndrome caused by aortic stenosis2024
- Author(s)
  Okubo N, Sugawara S, Fujiwara T, Sakatsume K, Doman T, Yamashita M, Goto K, Tateishi M, Suzuki M, Shirakawa R, Eura Y, Kokame K, Hayakawa M, Matsumoto M, Kawate Y, Miura M, Takiguchi H, Soga Y, Shirai S, Ando K, Arai Y, Nakayoshi T, Fukumoto Y, Takahama H, Yasuda S, Tamura T, Watanabe S, Kimura T, et al
- Journal Title
  
  Research and Practice in Thrombosis and Haemostasis
  
  Volume: 8 Issue: 1 Pages: 102284-102284
- DOI
  10.1016/j.rpth.2023.102284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-23K07567, KAKENHI-PROJECT-23K25186, KAKENHI-PROJECT-23K27372, KAKENHI-PROJECT-22K08461, KAKENHI-PROJECT-23K07849
[Journal Article] Excessive cleavage of von Willebrand factor multimers by ADAMTS13 may predict the progression of transplant-associated thrombotic microangiopathy2024
- Author(s)
  Yamada Shinya、Sakai Kazuya、Kubo Masayuki、Okumura Hirokazu、Asakura Hidesaku、Miyamoto Toshihiro、Matsumoto Masanori
- Journal Title
  
  Research and Practice in Thrombosis and Haemostasis
  
  Volume: 8 Issue: 5 Pages: 102517-102517
- DOI
  10.1016/j.rpth.2024.102517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08461, KAKENHI-PROJECT-22K09136
[Journal Article] ADAMTS13 conformation and immunoprofiles in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura2023
- Author(s)
  Sakai Kazuya、Matsumoto Masanori、De Waele Laure、Dekimpe Charlotte、Hamada Eriko、Kubo Masayuki、Tersteeg Claudia、De Meyer Simon F.、Vanhoorelbeke Karen
- Journal Title
  
  Blood Advances
  
  Volume: 7 Issue: 1 Pages: 131-140
- DOI
  10.1182/bloodadvances.2022008885
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08461
[Journal Article] Overlapping ADAMTS13 peptide binding profiles of DRB1?08:03 and DRB1?11:01 suggest a common etiology of immune-mediated thrombotic thrombocytopenic purpura2023
- Author(s)
  Sakai Kazuya、Miyadera Hiroko、Kubo Masayuki、Nakajima Fumiaki、Matsumoto Masanori
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 21 Issue: 3 Pages: 616-628
- DOI
  10.1016/j.jtha.2022.09.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08461
[Journal Article] Distinguishing immune-mediated thrombotic thrombocytopenic purpura from septic disseminated intravascular coagulation using plasma levels of haptoglobin and factor XIII activity2023
- Author(s)
  Yamada Shinya、Asakura Hidesaku、Kubo Masayuki、Sakai Kazuya、Miyamoto Toshihiro、Matsumoto Masanori
- Journal Title
  
  Research and Practice in Thrombosis and Haemostasis
  
  Volume: 7 Issue: 2 Pages: 100076-100076
- DOI
  10.1016/j.rpth.2023.100076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08461, KAKENHI-PROJECT-22K09136, KAKENHI-PROJECT-21H02951, KAKENHI-PROJECT-22K19544
[Journal Article] Frontiers in pathophysiology and management of thrombotic thrombocytopenic purpura2023
- Author(s)
  Kubo Masayuki、Matsumoto Masanori
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Pages: 331-340
- DOI
  10.1007/s12185-023-03552-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08461
[Journal Article] No aggravation of congenital thrombotic thrombocytopenic purpura by mRNA-based vaccines against COVID-19: a Japanese registry survey2022
- Author(s)
  Hamada Eriko、Sakai Kazuya、Yamada Shinya、Kubo Masayuki、Hayakawa Masaki、Matsumoto Masanori
- Journal Title
  
  Annals of Hematology
  
  Volume: 101 Issue: 5 Pages: 1115-1117
- DOI
  10.1007/s00277-022-04774-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08461
[Presentation] Recurrent thrombocytopenia during caplacizumab treatment in patients with acute immune-mediated thrombotic thrombocytopenic purpura after the clinical response.2024
- Author(s)
  16.Kenki Saito, Kazuya Sakai, Masayuki Kubo, Hidekazu Azumi, Atsushi Hamamura, Masanori Matsumoto.
- Organizer
  32nd Congress of the International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08461
[Presentation] Immediate Therapeutic Intervention for Acute Mortality in Immune-Mediated Thrombotic Thrombocytopenic Purpura with Positive Chest Findings at Initial Presentation.2024
- Author(s)
  Atsushi Hamamura, Kazuya Sakai, Toshiki Mushino, Yasunori Ueda, Yoshiyuki Ogawa, Hiroyuki Noguchi, Akinao Okamoto, Hisako Kunieda, Shinichi Ochi, Takashi Onaka, Daichi Nishiyama, Nobuhiko Uoshima, Yasuyuki Arai, Akira Matsumoto, Kenki Saito, Hidekazu Azumi, Masayuki Kubo, Hideo Yagi, Takashi Sonoki, Masanori Matsumoto.
- Organizer
  66th ASH Annual Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08461
[Presentation] 化学発光酵素免疫測定装置を用いた新規 ADAMTS13 活性迅速検査の有用性2024
- Author(s)
  久保政之, 松本雅則
- Organizer
  第18回日本血栓止血学会学術標準化委員会(SSC)シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K08461
[Presentation] 695 Persistent ADAMTS13 Inhibitor May Lead to Delayed ADAMTS13 Recovery in Japanese Patients with Caplacizumab-Treated Immune-Mediated Thrombotic Thrombocytopenic Purpura.2023
- Author(s)
  Kenki Saito, Kazuya Sakai, Masayuki Kubo, Hidekazu Azumi, Atsushi Hamamura, Shinichi Ochi, Shinya Kobayashi, Hideo Yagi, Masanori Matsumoto.
- Organizer
  The 66th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08461
[Presentation] Evaluation of a novel ADAMTS13 activity reagent using fully automated analyzer.2023
- Author(s)
  Masayuki Kubo, Kazuyasu Konko, Emi Kinoshita, Satoshi Uemae, Katsushi Kobayashi, Yoshihiro Fujimura, Masanori Matsumoto.
- Organizer
  the 31st Congress of the International Society on Thrombosis and Haemostasis (ISTH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08461
[Presentation] 新型コロナウイルスワクチンによる血栓性血小板減少性紫斑病患者への影響2022
- Author(s)
  濱田恵理子, 山田真也, 酒井和哉, 久保政之, 早川正樹, 松本雅則
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08461
[Presentation] Differential Diagnosis Distinguishing Immune TTP from Septic DIC Using Plasma Levels of Haptoglobin and Factor XIII Activity.2022
- Author(s)
  Shinya Yamada, Masayuki Kubo, Eriko Hamada, Kenki Saito, Masaki Hayakawa, Hidesaku Asakura, Masanori Matsumoto.
- Organizer
  64th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08461
[Presentation] ADAMTS13 Conformation and Immunoprofiles in Japanese Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura.2022
- Author(s)
  Kazuya Sakai, Masanori Matsumoto, Laure De Waele, Charlotte Dekimpe, Eriko Hamada, Masayuki Kubo, Claudia Tersteeg, Simon F De Meyer, Karen Vanhoorelbeke.
- Organizer
  64th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08461

1. Matsumoto Masanori (60316081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
2. 早川正樹 (30516729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 山田真也 (50927803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 齋藤健貴 (30972400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 藤原亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubo Masayuki 久保 政之

久保 政之 クボ マサユキ

Research Projects

Research Products

Co-Researchers

Development of an animal model of acquired thrombotic thrombocytopenic purpura

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A novel automated chemiluminescent enzyme immunoassay for ADAMTS-13 activity enables accompanying measurements of the inhibitory autoantibodies2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Persistent ADAMTS13 Inhibitor Delays Recovery of ADAMTS13 activity in Caplacizumab-Treated Japanese iTTP Patients2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] von Willebrand factor Ristocetin co-factor activity to von Willebrand factor antigen level ratio for diagnosis of acquired von Willebrand syndrome caused by aortic stenosis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Excessive cleavage of von Willebrand factor multimers by ADAMTS13 may predict the progression of transplant-associated thrombotic microangiopathy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ADAMTS13 conformation and immunoprofiles in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overlapping ADAMTS13 peptide binding profiles of DRB1?08:03 and DRB1?11:01 suggest a common etiology of immune-mediated thrombotic thrombocytopenic purpura2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinguishing immune-mediated thrombotic thrombocytopenic purpura from septic disseminated intravascular coagulation using plasma levels of haptoglobin and factor XIII activity2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Frontiers in pathophysiology and management of thrombotic thrombocytopenic purpura2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] No aggravation of congenital thrombotic thrombocytopenic purpura by mRNA-based vaccines against COVID-19: a Japanese registry survey2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Recurrent thrombocytopenia during caplacizumab treatment in patients with acute immune-mediated thrombotic thrombocytopenic purpura after the clinical response.2024

Author(s)

Organizer

Data Source

[Presentation] Immediate Therapeutic Intervention for Acute Mortality in Immune-Mediated Thrombotic Thrombocytopenic Purpura with Positive Chest Findings at Initial Presentation.2024

Author(s)

Organizer

Data Source

[Presentation] 化学発光酵素免疫測定装置を用いた新規 ADAMTS13 活性迅速検査の有用性2024

Author(s)

Organizer

Data Source

[Presentation] 695 Persistent ADAMTS13 Inhibitor May Lead to Delayed ADAMTS13 Recovery in Japanese Patients with Caplacizumab-Treated Immune-Mediated Thrombotic Thrombocytopenic Purpura.2023

Author(s)

Organizer

Data Source

[Presentation] Evaluation of a novel ADAMTS13 activity reagent using fully automated analyzer.2023

Author(s)

Organizer

Data Source

[Presentation] 新型コロナウイルスワクチンによる血栓性血小板減少性紫斑病患者への影響2022

Author(s)

Organizer

Data Source

Kubo Masayuki 久保政之

久保政之クボマサユキ