Mizutani Yusuke 水谷祐輔

Researcher Number	40646238
Other IDs
Affiliation (Current)	2025: 北海道大学, 総合IR本部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 北海道大学, 総合IR本部, 准教授 2021 – 2022: 北海道大学, 総合IR室, 准教授 2019 – 2020: 北海道大学, 総合IR室, 特任准教授 2016 – 2018: 新潟大学, 医歯学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / General anatomy (including histology/embryology) Except Principal Investigator Basic Section 50010:Tumor biology-related / General anatomy (including histology/embryology) / Thin film/Surface and interfacial physical properties
Keywords	Principal Investigator 細胞質突起 / イオンコンダクタンス顕微鏡 / 画像解析 / 機械学習 / アクチン線維 / 走査型イオンコンダクタンス顕微鏡 / 細胞骨格 / ３次元ダイナミクスイメージング Except Principal Investigator 細胞と組織 / バイオイメージング … More / 悪性化 / がん / がん悪性化 / 口腔上皮がん / Galectin4 / 細胞接着 / 細胞移動能 / SLPI / 生きた観察 / 組織 / 細胞 / 大気圧観察 / 大気圧 / ライブイメージング / 走査電子顕微鏡 / イメージング / 液中３D観察 / 細胞・組織 / 走査プローブ顕微鏡 Less

Further application of machine learning to scanning ion conduction microscopy to analyze the dynamics of cell motilityPrincipal Investigator
- Principal Investigator
  
  水谷祐輔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Hokkaido University
A novel approach for analyzing the three-dimensional dynamics of cell motility by the combined use of scanning ion conductance microscopy and machine-learningPrincipal Investigator
- Principal Investigator
  
  水谷祐輔
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Hokkaido University
Study of the mechanism underlying secretory leukocyte protease inhibitor (SLPI)-induced malignancy of cancer
- Principal Investigator
  
  Mikami Yoshikazu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Niigata University
Three dimensional dynamics of apical membrane ruffles on living cells by scanning ion conductance microscopyPrincipal Investigator
- Principal Investigator
  
  Mizutani Yusuke
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Hokkaido University
  Niigata University
Imaging of cells and tissues in liquid by scanning ion conductance microscopy
- Principal Investigator
  
  USHIKI TATSUO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thin film/Surface and interfacial physical properties
- Research Institution
  Niigata University
Imaging of live cells and tissues by atmospheric scanning electron microscopy
- Principal Investigator
  
  USHIKI TATSUO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Niigata University

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] Scanning Ion Conductance Microscopy (Bioanalytical Reviews, 3)2022
- Author(s)
  L. A. Baker, A. Bhargava, M.-H. Choi, I. D. Dietzel, A. Gesper, J. Gorelik, A. Haak, P. Happel, F. Iwata, Y. Korchev, C. W. Leasor , M. V. Makarova, Y. Mizutani, M. Nakajima, P. Novak, T. E. Schaeffer, A. Shevchuk, Y. Takahashi, T. Ushiki, H. von Eysmondt
- Total Pages
  241
- Publisher
  Springer
- ISBN
  9783031144424
- Data Source
  KAKENHI-PROJECT-20K07217
[Journal Article] Scanning ion conductance microscopy of isolated metaphase chromosomes in a liquid environment2021
- Author(s)
  T. Ushiki, K. Ishizaki, Y. Mizutani, M. Nakajima, F. Iwata
- Journal Title
  
  Chromosome Research
  
  Volume: 29 Issue: 1 Pages: 95-106
- DOI
  10.1007/s10577-021-09659-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22126, KAKENHI-PROJECT-17H06122, KAKENHI-PROJECT-20K07217
[Journal Article] Scanning ion-conductance microscopy with a double-barreled nanopipette for topographic imaging of charged chromosomes2021
- Author(s)
  Iwata Futoshi、Shirasawa Tatsuru、Mizutani Yusuke、Ushiki Tatsuo
- Journal Title
  
  Microscopy
  
  Volume: － Issue: 5 Pages: 423-435
- DOI
  10.1093/jmicro/dfab009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15541, KAKENHI-PROJECT-19K22126, KAKENHI-PROJECT-17H06122, KAKENHI-PROJECT-20K07217
[Journal Article] SLPI facilitates cell migration by regulating lamellipodia/ruffles and desmosomes, in which Galectin4 plays an important role2020
- Author(s)
  Mizutani Yusuke、Omagari Daisuke、Hayatsu Manabu、Nameta Masaaki、Komiyama Kazuo、Mikami Yoshikazu、Ushiki Tatsuo
- Journal Title
  
  Cell Adhesion & Migration
  
  Volume: 14 Issue: 1 Pages: 195-203
- DOI
  10.1080/19336918.2020.1829264
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07217, KAKENHI-PROJECT-18K07226, KAKENHI-PROJECT-17K15541
[Journal Article] Micropillar fabrication based on local electrophoretic deposition using a scanning ion conductance microscope with a theta nanopipette2019
- Author(s)
  Yoshioka Masayoshi、Mizutani Yusuke、Ushiki Tatsuo、Nakazawa Kenta、Iwata Futoshi
- Journal Title
  
  Japanese Journal of Applied Physics
  
  Volume: 58 Issue: 4 Pages: 046503-046503
- DOI
  10.7567/1347-4065/ab03e4
- NAID
  210000135467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06122, KAKENHI-PROJECT-16H03868
[Journal Article] Dual effect of polyphosphate on mineralization of rat osteoblast ROS17/2.8 cells in a dose-dependent manner2018
- Author(s)
  Mikami Y, Omagari D, Mizutani Y, Hayatsu M, Ushiki T, Tsuda H
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 138 Issue: 3 Pages: 209-213
- DOI
  10.1016/j.jphs.2018.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07226
[Journal Article] Scanning ion conductance microscopy for visualizing the three-dimensional surface topography of cells and tissues2018
- Author(s)
  M Nakajima, Y Mizutani, F Iwata, T Ushiki
- Journal Title
  
  Seminars in Cell & Developmental Biology
  
  Volume: 73 Pages: 125-131
- DOI
  10.1016/j.semcdb.2017.09.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 細胞分裂に伴う核膜の動態に関する構造学的解析2022
- Author(s)
  早津学、水谷祐輔、三上剛和
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07217
[Presentation] Scanning ion conductance microscopy for visualizing the surface topography of rat tissue sections2021
- Author(s)
  Yusuke Mizutani, Manabu Hayatsu, Yoshikazu Mikami, Tatsuo Ushiki
- Organizer
  第126回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07217
[Presentation] Scanning ion conductance microscopy for visualizing the surface topography of rat tissue sections2021
- Author(s)
  Mizutani Yusuke、Hayatsu Manabu、Mikami Yoshikazu、Ushiki Tatsuo
- Organizer
  第126回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] Scanning ion conductance microscopy for visualizing the surface topography of rat tissue sections.2021
- Author(s)
  Mizutani Y, Hayatsu M, Mikami Y, Ushiki T.
- Organizer
  第126回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-18K07226
[Presentation] イオン伝導顕微鏡による組織切片表面の微細構造イメージング2020
- Author(s)
  水谷祐輔，早津学，三上剛和，牛木辰男
- Organizer
  第125回日本解剖学会総会・全国集会
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] Secretory leukocyte protease inhibitor による細胞移動能の制御機構に関する研究2020
- Author(s)
  三上剛和, 福島敦史, 水谷祐輔，早津学，小宮山一雄，牛木辰男
- Organizer
  第125回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-18K07226
[Presentation] イオン伝導顕微鏡による細胞・組織イメージング2019
- Author(s)
  水谷祐輔，早津学，三上剛和，牛木辰男
- Organizer
  第124回日本解剖学会総会・全国集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] 走査型イオン伝導顕微鏡による組織・細胞観察2019
- Author(s)
  水谷祐輔，牛木辰男
- Organizer
  2019年度精密工学会春季大会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] イオン電導顕微鏡による細胞・組織イメージング2019
- Author(s)
  水谷祐輔、早津　学、三上剛和、牛木辰男
- Organizer
  第124回日本解剖学会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 走査型イオン伝導顕微鏡を用いた組織切片表面微細構造解析2019
- Author(s)
  水谷祐輔，山川明里，早津学，牛木辰男
- Organizer
  第75回日本顕微鏡学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] 細胞表面微細構造と移動能の関連性についての走査型イオン伝導顕微鏡による解析2018
- Author(s)
  水谷祐輔，三上剛和，牛木辰男
- Organizer
  第74回日本顕微鏡学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] Simultaneous observation of the cell surface structure and cytoskeleton by scanning ion conductance microscopy and fluorescence microscopy2018
- Author(s)
  Y. Mizutani, Y. Mikami, M. Hayatsu, T. Ushiki
- Organizer
  The 20th International Scanning Probe Microscopy Conference (ISPM 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] 細胞表面微細構造と移動能の関連性についての走査型イオン電子顕微鏡による解析2018
- Author(s)
  水谷祐輔、三上剛和、牛木辰男
- Organizer
  日本顕微鏡学会第74回学術講演会
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] Scanning ion conductance microscopy for cell and tissue research2018
- Author(s)
  Ushiki T, Mizutani Y
- Organizer
  International Symposium on Morphological Sciences (ISMS) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] Simultaneous observation of the cell surface structure and cytoskeleton by scanning ion conductance microscopy and fluorescence microscopy2018
- Author(s)
  Mizutani Y,Mikami Y,Hayatsu M, Ushiki T
- Organizer
  International Scanning Probe Microscopy (ISPM) Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] イオン伝導顕微鏡による細胞・組織イメージング2018
- Author(s)
  水谷祐輔、早津学、三上剛和、牛木辰男
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-18K07226
[Presentation] 走査型イオン伝導顕微鏡による細胞膜表面観察とがん細胞動態解析への応用2018
- Author(s)
  水谷祐輔、三上剛和、早津学、牛木辰男
- Organizer
  第123回日本解剖学会総会・全国集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] Movement of oral carcinoma cells investigated by scanning ion conductance microscopy.2017
- Author(s)
  Y. Mizutani, Y. Yamada, Y. Mikami, T. Ushiki
- Organizer
  The 19th International Scanning Probe Microscopy Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 走査型イオン伝導顕微鏡による生体組織イメージング法の開発2017
- Author(s)
  牛木辰男，岩田太，水谷祐輔，吉岡正義
- Organizer
  平成28年度生体医歯工学共同研究拠点成果報告会
- Place of Presentation
  東京医科歯科大学（東京都文京区）
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 走査型イオンコンダクタンス顕微鏡と蛍光顕微鏡による培養細胞の相補観察2017
- Author(s)
  水谷祐輔　三上　牛木辰男
- Organizer
  第122回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 走査型イオンコンダクタンス顕微鏡と蛍光顕微鏡による培養細胞の相補観察2017
- Author(s)
  水谷祐輔、三上剛和、牛木辰男
- Organizer
  第122回日本解剖学会総会・全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス（長崎県長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] Movement of oral carcinoma cells investigated by scanning ion conductance microscopy2017
- Author(s)
  Y. Mizutani, Y. Yamada, Y. Mikami, T. Ushiki
- Organizer
  The 19th International Scanning Probe Microscopy Conference (ISPM 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15541
[Presentation] シータ管ナノピペットを用いた走査型イオン伝導顕微鏡による試料表面帯電を相殺した計測法の開発2017
- Author(s)
  白澤　樹，江口由祐，水谷祐輔，牛木辰男，岩田太
- Organizer
  日本機械学会東海支部第66期総会・講演会
- Place of Presentation
  静岡大学浜松キャンパス（静岡県浜松市）
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 複数開口プローブを有する走査型イオン伝導顕微鏡を用いた帯電試料のイメージング2016
- Author(s)
  白澤樹、江口由祐、水谷祐輔、牛木辰男、岩田太
- Organizer
  2016年度精密工学会秋季大会
- Place of Presentation
  茨城大学水戸キャンパス（茨城県水戸市）
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 複数開口プローブを有する走査型イオン伝導顕微鏡を用いた帯電試料イメージング2016
- Author(s)
  白澤樹，江口由祐，水谷祐輔，牛木辰男，岩田太
- Organizer
  第77回応用物理学会秋季学術講演会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2016-09-13
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] Time lapse imaging of living cells using scanning ion conductance microscopy2016
- Author(s)
  Yusuke Mizutani, Tatsuo Ushiki
- Organizer
  International Scanning Probe Microscopy (ISPM) Conference
- Place of Presentation
  Grindelwald, Switzerland
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] Imaging of biological tissue blocks in liquid by scanning ion conductance microscopy2016
- Author(s)
  Tatsuo Ushiki, Yusuke Mizutani, Tatsuru Shirasawa, Futoshi Iwata
- Organizer
  International Scanning Probe Microscopy (ISPM) Conference
- Place of Presentation
  Grindelwald, Switzerland
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 走査型イオンコンダクタンス顕微鏡による培養細胞表面のタイムラプス解析2016
- Author(s)
  水谷祐輔、牛木辰男
- Organizer
  日本顕微鏡学会SPM分科会
- Place of Presentation
  ホテルニューオータニ越後湯沢（新潟県南魚沼郡湯沢町）
- Year and Date
  2016-11-13
- Data Source
  KAKENHI-PROJECT-16H03868
[Presentation] 走査型イオン伝導顕微鏡イメージングにおける複数開口ナノピペットを用いた試料表面帯電の影響低減2016
- Author(s)
  白澤　樹，江口由祐，水谷祐輔，牛木辰男，岩田太
- Organizer
  2016年真空・表面科学合同講演会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2016-11-29
- Data Source
  KAKENHI-PROJECT-16H03868

1. Mikami Yoshikazu (80434075)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. USHIKI TATSUO (40184999)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. 岩田太 (30262794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 中島真人 (60588250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 上原範久 (30368211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 早津学 (40468898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 津田啓方 (60325470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 福島敦史 (80415281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KAJIMURA koji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Mizutani Yusuke 水谷 祐輔

Research Projects

Research Products

Co-Researchers

Further application of machine learning to scanning ion conduction microscopy to analyze the dynamics of cell motilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel approach for analyzing the three-dimensional dynamics of cell motility by the combined use of scanning ion conductance microscopy and machine-learningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of the mechanism underlying secretory leukocyte protease inhibitor (SLPI)-induced malignancy of cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Three dimensional dynamics of apical membrane ruffles on living cells by scanning ion conductance microscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Imaging of cells and tissues in liquid by scanning ion conductance microscopy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Imaging of live cells and tissues by atmospheric scanning electron microscopy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Scanning Ion Conductance Microscopy (Bioanalytical Reviews, 3)2022

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Scanning ion conductance microscopy of isolated metaphase chromosomes in a liquid environment2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Scanning ion-conductance microscopy with a double-barreled nanopipette for topographic imaging of charged chromosomes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SLPI facilitates cell migration by regulating lamellipodia/ruffles and desmosomes, in which Galectin4 plays an important role2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Micropillar fabrication based on local electrophoretic deposition using a scanning ion conductance microscope with a theta nanopipette2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Dual effect of polyphosphate on mineralization of rat osteoblast ROS17/2.8 cells in a dose-dependent manner2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Scanning ion conductance microscopy for visualizing the three-dimensional surface topography of cells and tissues2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 細胞分裂に伴う核膜の動態に関する構造学的解析2022

Author(s)

Organizer

Mizutani Yusuke 水谷祐輔