Nagasaki Tadao 長崎忠雄

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nagasaki tadao 長崎忠雄

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Researcher Number	40747862
Other IDs
Affiliation (Current)	2025: 近畿大学, 奈良病院, 講師 2025: 京都大学, 医学研究科, 特定助教
Affiliation (based on the past Project Information) *help	2023: 近畿大学, 奈良病院, 講師 2021 – 2022: 京都大学, 医学研究科, 特定助教 2016 – 2018: 京都大学, 医学研究科, 医員 2015: 京都大学, 医学(系)研究科(研究院), その他
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator 喘息 / asthma / 2型炎症 / 酸化ストレス / ヒト気道上皮細胞 / Type-2 inflammation / 15 lipoxygenase-1 / SLC7A11 / ferroptosis / glutathione … More / redox balance / アレルギー・ぜんそく / COPD / 好酸球性炎症 / 黄色ブドウ球菌 / 喫煙 / Staphylococcal / Smoking / Eosinophilic … More Except Principal Investigator periostin / IL4RA / ゲノム / アレルギー・喘息 / 肥満 / inflammasome / 血清IL-18 / ORMDL3 / IL-18 / 分子細胞呼吸器学 / 疾患モデリング / 肺臓器再生 / iPS細胞 / 分子細胞呼吸学 Less

Association between oxidative stress and Type2 inflammation in asthmaPrincipal Investigator
- Principal Investigator
  
  nagasaki tadao
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kindai University
  Kyoto University
Understanding of pathogenesis of severe asthma and its exacerbation through geno-endo-phenotyping
- Principal Investigator
  
  Matsumoto Hisako
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Phenotype and biomarkers of the asthma COPD overlap syndromePrincipal Investigator
- Principal Investigator
  
  Nagasaki Tadao
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Application of iPS cell technology to lung regeneration and development of bioresource for elucidating the mechanisms of lung diseases
- Principal Investigator
  
  Michiaki Mishima
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University

All 2024 2023 2022 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 最新醫學別冊診断と治療のABC135喘息2018
- Author(s)
  長崎忠雄
- Total Pages
  3
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-16K19450
[Book] 呼吸器疾患　診断治療アプローチ2017
- Author(s)
  長崎忠雄・松本久子
- Total Pages
  5
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-16K19450
[Book] アレルギーの臨床2017
- Author(s)
  長崎忠雄・松本久子
- Total Pages
  4
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-16K19450
[Journal Article] Evaluation of elevated plasma fatty acids as relevant factors for adult-onset asthma: The Nagahama Study2024
- Author(s)
  Tashima Noriyuki、Matsumoto Hisako、Nishi Kenta、Terada Satoru、Kogo Mariko、Nomura Natsuko、Morimoto Chie、Sunadome Hironobu、Nagasaki Tadao、Oguma Tsuyoshi、Nakatsuka Yoshinari、Murase Kimihiko、Kawaguchi Takahisa、Tabara Yasuharu、Chin Kazuo、Sonomura Kazuhiro、Matsuda Fumihiko、Hirai Toyohiro
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 1 Pages: 65-70
- DOI
  10.1016/j.alit.2023.04.005
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16117, KAKENHI-PROJECT-21H04850
[Journal Article] Sputum microbiota and inflammatory subtypes in asthma, COPD, and its overlap2024
- Author(s)
  Morimoto Chie、Matsumoto Hisako、Nomura Natsuko、Sunadome Hironobu、Nagasaki Tadao、Sato Susumu、Sato Atsuyasu、Oguma Tsuyoshi、Ito Isao、Kogo Mariko、Tomii Keisuke、Tajiri Tomoko、Ohashi Kai、Tsukahara Takamitsu、Hirai Toyohiro
- Journal Title
  
  Journal of Allergy and Clinical Immunology: Global
  
  Volume: 3 Issue: 1 Pages: 100194-100194
- DOI
  10.1016/j.jacig.2023.100194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08271, KAKENHI-PROJECT-21K16117
[Journal Article] Increased blood eosinophils and airflow obstruction as new-onset asthma predictors in the elderly: The Nagahama study2024
- Author(s)
  Nishi Kenta、Nagasaki Tadao、Matsumoto Hisako、Oguma Tsuyoshi、Terada Satoru、Nomura Natsuko、Kogo Mariko、Tashima Noriyuki、Sunadome Hironobu、Murase Kimihiko、Matsumoto Takeshi、Kawaguchi Takahisa、Tabara Yasuharu、Matsuda Fumihiko、Sato Susumu、Chin Kazuo、Hirai Toyohiro
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 2 Pages: 236-242
- DOI
  10.1016/j.alit.2023.11.002
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16117, KAKENHI-PROJECT-21H04850
[Journal Article] Associations between Nocturnal Hypoxemia and Retinal Nerve Fiber Layer Thinning: The Nagahama Study2024
- Author(s)
  Nagasaki Tadao、Miyake Masahiro、Sato Susumu、Murase Kimihiko et al.
- Journal Title
  
  Annals of the American Thoracic Society
  
  Volume: 21 Issue: 4 Pages: 644-650
- DOI
  10.1513/annalsats.202304-355oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17674, KAKENHI-PROJECT-21K16117, KAKENHI-PROJECT-21H04850
[Journal Article] Effectiveness of bronchial thermoplasty in patients with asthma exhibiting overweight/obesity and low quality of life2023
- Author(s)
  Nishi Kenta、Yoshimura Chie、Morita Kyohei、Ishikawa Ryoichi、Toyokura Erika、Nagasaki Tadao、Matsumoto Hisako、Nishizaka Yasuo
- Journal Title
  
  World Allergy Organization Journal
  
  Volume: 16 Issue: 3 Pages: 100756-100756
- DOI
  10.1016/j.waojou.2023.100756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16117
[Journal Article] Age-specific associations of early daycare, older siblings, severe airway infection, and preterm birth with subsequent atopic diseases2022
- Author(s)
  Nagasaki T, Tabuchi T, Matsumoto H, Horimukai K.
- Journal Title
  
  Pediatr Allergy Immunol.
  
  Volume: 33 Issue: 4
- DOI
  10.1111/pai.13771
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16117
[Journal Article] 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation2022
- Author(s)
  Nagasaki T, Schuyler AJ, Zhao J, Samovich SN, Yamada K, Deng Y, Ginebaugh SP, Christenson SA, Woodruff PG, Fahy JV, Trudeau JB, Stoyanovsky D, Ray A, Tyurina YY, Kagan VE, Wenzel SE.
- Journal Title
  
  J Clin Invest.
  
  Volume: 132 Issue: 1
- DOI
  10.1172/jci151685
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16117
[Journal Article] The prevalence and disease burden of severe eosinophilic asthma in Japan.2019
- Author(s)
  Nagasaki T, Sato K, Kume N, Matsumoto H. et al.
- Journal Title
  
  J Asthma
  
  Volume: Epub Issue: 11 Pages: 1147-1158
- DOI
  10.1080/02770903.2018.1534967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09535
[Journal Article] Long-term expansion of alveolar stem cells derived from human iPS cells in organoids2017
- Author(s)
  Yamamoto Yuki、Gotoh Shimpei、Korogi Yohei、Seki Masahide、Konishi Satoshi、Ikeo Satoshi、Sone Naoyuki、Nagasaki Tadao、Matsumoto Hisako、Muro Shigeo、Ito Isao、Hirai Toyohiro、Kohno Takashi、Suzuki Yutaka、Mishima Michiaki
- Journal Title
  
  Nature Methods
  
  Volume: 14 Issue: 11 Pages: 1097-1106
- DOI
  10.1038/nmeth.4448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09536, KAKENHI-PROJECT-15H02537, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17H05084
[Journal Article] Sensitization to Staphylococcus aureus enterotoxins in smokers with asthma2017
- Author(s)
  Tadao Nagasaki; Hisako Matsumoto; Tsuyoshi Oguma;Isao Ito; Hideki Inoue; Toshiyuki Iwata; Tomoko Tajiri; Yoshihiro Kanemitsu; Yumi Izuhara; Chie Morimoto; Yumi Ishiyama; Hironobu Sunadome; Akio Niimi; Toyohiro Hirai;
- Journal Title
  
  Annals of Allergy, Asthma & Immunology
  
  Volume: 119 Issue: 5 Pages: 408-414
- DOI
  10.1016/j.anai.2017.08.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19450
[Presentation] 2型炎症におけるフェロトーシス2024
- Author(s)
  長崎忠雄
- Organizer
  日本呼吸器学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K16117
[Presentation] 酸化ストレスと2型炎症2023
- Author(s)
  長崎忠雄
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K16117
[Presentation] 成人喘息の新規発症に関わるリスク因子における性差2022
- Author(s)
  長崎忠雄、西健太、松本久子、小熊毅、砂留広伸、村瀬公彦、松本健、田嶋範之、野村奈都子、古郷摩利子、寺田悟、田原康玄、松田文彦、佐藤晋、陳和夫、平井豊博
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K16117
[Presentation] Long-term expansion of alveolar stem cells derived from human iPS cells by forming organoids2017
- Author(s)
  山本佑樹、後藤慎平、興梠陽平、関真秀、小西聡史、池尾聡、曽根尚之、長崎忠雄、松本久子、室繁郎、伊藤功朗、平井豊博、河野隆志、鈴木穣、三嶋理晃
- Organizer
  CiRA 2017 International Symposium
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] In vitro disease modeling of alveolar phenotype caused by AP3B1 deficiency using human induced pluripotent stem cells.2017
- Author(s)
  Korogi Y, Gotoh S, Yamamoto Y, Konishi S, Nagasaki T, Sone N, Ikeo S, Matsumoto H, Muro S, Ito I, Asaka I, Hotta A, Hirai T
- Organizer
  Stem Cell Research 15th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] Both Eosinophilic and Neutrophilic Inflammation were Associated with Pulmonary Function in Ex-smokers with Asthma2016
- Author(s)
  T. Nagasaki, H. Matsumoto, T. Oguma, H. Inoue, T.Iwata, T. Tajiri, Y. Kanemitsu, Y. Izuhara, H. Sunadome, I. Ito, A. Niimi, M. Mishima
- Organizer
  American Thoracic Society conference
- Place of Presentation
  San Francisco
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19450
[Presentation] ヒトiPS細胞から機能的な気道線毛上皮細胞への分化誘導2016
- Author(s)
  小西聡史、後藤慎平、立石和博、山本佑樹、興梠陽平、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、月田早智子、三嶋理晃
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] Long-term culture of alveolar epithelial type 2 cells derived from human induced pluripotent stem cells.2016
- Author(s)
  山本佑樹、後藤慎平、興梠陽平、小西聡史、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、三嶋理晃
- Organizer
  International Society for Stem Cell Research 14th Annual Meeting
- Place of Presentation
  Samfrancisco, USA
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] Smoking and Staphylococcus aureus enterotoxin sensitization in adults with asthma2016
- Author(s)
  Tadao Nagasaki, Hisako Matsumoto, Tsuyoshi Oguma, Isao Ito, Hideki Inoue, Toshiyuki Iwata, Tomoko Tajiri, Yoshihiro Kanemitsu, Yumi Izuhara, Akio Niimi, Michiaki Mishima
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K19450
[Presentation] クラスター解析；方法論から臨床応用まで2016
- Author(s)
  長崎忠雄、松本久子
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-04-08
- Invited
- Data Source
  KAKENHI-PROJECT-16K19450
[Presentation] ヒトiPS細胞から気道繊毛上皮前駆細胞への効率の良い分化誘導法の確立2015
- Author(s)
  小西聡史、後藤慎平、山本佑樹、興梠陽平、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、三嶋理晃
- Organizer
  第55回日本呼吸器学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] Generation of ciliated airway epithelial cells from human induced pluripotent stem cells2015
- Author(s)
  小西聡史、後藤慎平、山本佑樹、興梠陽平、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、三嶋理晃
- Organizer
  ISSCR 2015 annual meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] ヒト多能性幹細胞から呼吸器上皮細胞への分化誘導2015
- Author(s)
  後藤慎平、伊藤功朗、興梠陽平、山本佑樹、小西聡史、長崎忠雄、松本久子、佐藤篤靖、室繁郎、平井豊博、長船健二、浅香勲、瀬山邦明、三嶋理晃
- Organizer
  第15回　日本細胞生物学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] ヒトiPS細胞からⅡ型肺胞上皮細胞への分化誘導効率の改善2015
- Author(s)
  山本佑樹、後藤慎平、興梠陽平、小西聡史、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、三嶋理晃
- Organizer
  第55回日本呼吸器学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] ヒトiPS細胞から気道線毛上皮細胞への分化誘導2015
- Author(s)
  小西聡史、後藤慎平、立石和博、山本佑樹、興梠陽平、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、月田早智子、三嶋理晃
- Organizer
  第38回　日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] 遺伝性呼吸器疾患の疾患特異的iPS細胞樹立2015
- Author(s)
  後藤慎平、伊藤功朗、興梠陽平、山本佑樹、小西聡史、長崎忠雄、松本久子、佐藤篤靖、室繁郎、平井豊博、長船健二、浅香勲、瀬山邦明、三嶋理晃
- Organizer
  第55回日本呼吸器学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15H02537

1. Matsumoto Hisako (60359809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. 小熊毅 (50601324)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Michiaki Mishima (60190625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 瀬山邦明 (10226681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 半田知宏 (10432395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 平井豊博 (20359805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. 金永学 (20456883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐藤篤靖 (30706677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 佐藤晋 (40378691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 伊藤功朗 (40447975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
11. 堀田秋津 (50578002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 後藤慎平 (50747219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
13. 室繁郎 (60344454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
14. 小笹裕晃 (80572015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 永井宏樹 (80711605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 陳和夫 (90197640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 浅香勲 (10543639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. 谷澤公伸 (20639140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 村瀬公彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagasaki Tadao 長崎 忠雄

nagasaki tadao 長崎 忠雄

Research Projects

Research Products

Co-Researchers

Association between oxidative stress and Type2 inflammation in asthmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding of pathogenesis of severe asthma and its exacerbation through geno-endo-phenotyping

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Phenotype and biomarkers of the asthma COPD overlap syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of iPS cell technology to lung regeneration and development of bioresource for elucidating the mechanisms of lung diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 最新醫學別冊 診断と治療のABC135喘息2018

Author(s)

Total Pages

Publisher

Data Source

[Book] 呼吸器疾患 診断治療アプローチ2017

Author(s)

Total Pages

Publisher

Data Source

[Book] アレルギーの臨床2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Evaluation of elevated plasma fatty acids as relevant factors for adult-onset asthma: The Nagahama Study2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Sputum microbiota and inflammatory subtypes in asthma, COPD, and its overlap2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased blood eosinophils and airflow obstruction as new-onset asthma predictors in the elderly: The Nagahama study2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Associations between Nocturnal Hypoxemia and Retinal Nerve Fiber Layer Thinning: The Nagahama Study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effectiveness of bronchial thermoplasty in patients with asthma exhibiting overweight/obesity and low quality of life2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Age-specific associations of early daycare, older siblings, severe airway infection, and preterm birth with subsequent atopic diseases2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation2022

Author(s)

Nagasaki Tadao 長崎忠雄

nagasaki tadao 長崎忠雄

[Book] 最新醫學別冊診断と治療のABC135喘息2018

[Book] 呼吸器疾患　診断治療アプローチ2017