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Takase Hinako M  高瀬 比菜子

ORCIDConnect your ORCID iD *help
Researcher Number 40754528
Other IDs
Affiliation (based on the past Project Information) *help 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 訪問研究員
2021: 東京医科歯科大学, 大学院医歯学総合研究科, テニュアトラック助教
2018 – 2021: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員
2017: 東京医科歯科大学, 大学院医歯学総合研究科, テニュアトラック助教
Review Section/Research Field
Principal Investigator
Basic Section 44020:Developmental biology-related / Biological Sciences / Urology
Except Principal Investigator
Animal production science
Keywords
Principal Investigator
卵巣 / 原始卵胞 / 卵母細胞 / Wntシグナル / 生殖生物学 / 卵胞形成 / 数理モデル / 不妊 / Wntシグナル伝達経路 / 生殖細胞 … More / 発生・分化 / ライディッヒ細胞 / セルトリ細胞 / 精子幹細胞 / Wnt / 未分化型精原細胞 / 精子形成 … More
Except Principal Investigator
マウス / AMH / テストステロン / 顆粒膜細胞 / セルトリ細胞 / 性分化 / heterogenity / 哺乳動物 / 性決定 / 卵精巣 / 性転換 / heterogeneity / 性的2型 / 支持細胞 Less
  • Research Projects

    (4 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (5 People)
  •  確率論的モデルからアプローチするマウス原始卵胞活性化プロセスの解明Principal Investigator

    • Principal Investigator
      高瀬 比菜子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  卵子成熟過程のインテグリティを支えるWntの原始卵胞活性化メカニズムPrincipal Investigator

    • Principal Investigator
      高瀬 比菜子
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
  •  The role of Wnt signaling underlying the regulation of undifferentiated spermatogoniaPrincipal Investigator

    • Principal Investigator
      Takase Hinako M
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Institute of Physical and Chemical Research
      Tokyo Medical and Dental University
  •  Molecular characterization of mouse gonadal supporting cell lineages in a partial sex reversal

    • Principal Investigator
      Kanai Yoshiakira
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Animal production science
    • Research Institution
      The University of Tokyo

All 2022 2021 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse.2022

    • Author(s)
      Uchida, A., Imaimatsu, K., Suzuki, H., Han, X., Ushioda, H., Uemura, M., Imura-Kishi, K., Hiramatsu, R., Takase, H. M., Hirate, Y., Ogura, A., Kanai-Azuma, M., Kudo, A., & Kanai, Y.
    • Journal Title

      Nature communications

      Volume: 13 (1) Issue: 1 Pages: 7860-7860

    • DOI

      10.1038/s41467-022-35465-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06193, KAKENHI-PROJECT-22K06022, KAKENHI-PROJECT-22KJ3144, KAKENHI-PROJECT-19K06397, KAKENHI-PLANNED-19H05758
  • [Journal Article] WNT signaling in pre-granulosa cells is required for ovarian folliculogenesis and female fertility2021

    • Author(s)
      Habara Okiko、Logan Catriona Y.、Kanai-Azuma Masami、Nusse Roeland、Takase Hinako M.
    • Journal Title

      Development

      Volume: 148 Issue: 9

    • DOI

      10.1242/dev.198846

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H05249, KAKENHI-PROJECT-21K06193
  • [Journal Article] Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules2021

    • Author(s)
      Imura-Kishi Kasane、Uchida Aya、Tsunekawa Naoki、Suzuki Hitomi、Takase Hinako M.、Hirate Yoshikazu、Kanai-Azuma Masami、Hiramatsu Ryuji、Kurohmaru Masamichi、Kanai Yoshiakira
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 1110-1110

    • DOI

      10.1038/s41598-020-79987-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06397, KAKENHI-PROJECT-19J22868, KAKENHI-PROJECT-18K05953, KAKENHI-PUBLICLY-19H05249, KAKENHI-PROJECT-17H01501
  • [Journal Article] Differentiation of ovaries.2018

    • Author(s)
      Takase MH, Kanai-Azuma M, Kanai Y
    • Journal Title

      Reference Module in Biomedical Sciences

      Pages: 1-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01501
  • [Journal Article] Spermatogonial deubiquitinase USP9X is essential for proper spermatogenesis in mice2017

    • Author(s)
      Kishi Kasane、Uchida Aya、Takase Hinako M、Suzuki Hitomi、Kurohmaru Masamichi、Tsunekawa Naoki、Kanai-Azuma Masami、Wood Stephen A、Kanai Yoshiakira
    • Journal Title

      Reproduction

      Volume: 154 Issue: 2 Pages: 135-143

    • DOI

      10.1530/rep-17-0184

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07688, KAKENHI-PROJECT-17K17690, KAKENHI-PROJECT-15J10266, KAKENHI-PROJECT-17H01501, KAKENHI-PUBLICLY-16H01251
  • [Presentation] Towards Elucidation of Oocyte-Somatic Cell Communication in Primordial Follicle Activation2021

    • Author(s)
      Takase Hinako M.
    • Organizer
      The 44th Annual Meeting of the Molecular Biology Society of Japan
    • Data Source
      KAKENHI-PUBLICLY-19H05249
  • [Presentation] Wnt signaling permits differentiation of pre-granulosa cells required for female fertility2021

    • Author(s)
      Takase Hinako M.
    • Organizer
      Wnt-meeting 2021
    • Data Source
      KAKENHI-PUBLICLY-19H05249
  • [Presentation] Towards Elucidation of Oocyte-Somatic Cell Communication in Primordial Follicle Activation2021

    • Author(s)
      Takase Hinako M.
    • Organizer
      The 44th Annual Meeting of the Molecular Biology Society of Japan
    • Data Source
      KAKENHI-PROJECT-21K06193
  • [Presentation] Wnt signaling permits differentiation of pre-granulosa cells required for female fertility2021

    • Author(s)
      Takase Hinako M.
    • Organizer
      Wnt-meeting 2021
    • Data Source
      KAKENHI-PROJECT-21K06193
  • [Presentation] Wnt signaling-mediated differentiation of pre-granulosa cell is critical for primordial follicle activation2019

    • Author(s)
      Hinako M. Takase
    • Organizer
      The 42nd Annual Meeting of the Molecular Biology Society of Japan (MBSJ2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H05249
  • [Presentation] Essential function of somatic cell-derived Wnt signaling in primordial follicle activation and fertility in female mice2019

    • Author(s)
      Hinako M Takase, Chunxiao Sun
    • Organizer
      BDR Symposium 2019, Control and Design of Biosystems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17690
  • [Presentation] Wnt signaling-mediated differentiation of pre-granulosa cell is critical for primordial follicle activation2019

    • Author(s)
      Hinako M. Takase
    • Organizer
      The 42nd Annual Meeting of the Molecular Biology Society of Japan (MBSJ2019)
    • Data Source
      KAKENHI-PROJECT-17K17690
  • [Presentation] マウス卵巣の卵胞形成におけるWntシグナルの役割2017

    • Author(s)
      Takase Hinako M、Fujita Sara、Hitomi Suzuki、Kanai-Azuma Masami
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17690
  • 1.  Kanai Yoshiakira (30260326)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  平松 竜司 (70555284)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  平手 良和 (70342839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  九郎丸 正道 (00148636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  TSUNEKAWA NAOKI
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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