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Tanaka Ichidai  田中 一大

ORCIDConnect your ORCID iD *help
Researcher Number 40809810
Other IDs
Affiliation (Current) 2025: 名古屋大学, 医学部附属病院, 病院講師
Affiliation (based on the past Project Information) *help 2020 – 2024: 名古屋大学, 医学部附属病院, 助教
2018 – 2021: 名古屋大学, 医学部附属病院, 病院助教
Review Section/Research Field
Principal Investigator
Basic Section 53030:Respiratory medicine-related
Except Principal Investigator
Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53030:Respiratory medicine-related
Keywords
Principal Investigator
細胞増殖 / PDXマウス / 新規治療標的 / ピリミジン代謝 / LKB1不活化肺癌 / 新規治療戦略 / 細胞周期停止 / 腫瘍増殖因子 / 新規個別化治療 / ドラッグリポジショニング … More / 予後因子 / 細胞周期制御因子 / オキシトシン受容体阻害剤 / オキシトシン / オキシトシン受容体 / 悪性中皮腫 / 非小細胞肺癌 / 予後予測 / 非小細胞肺がん / 予後予測因子 / 血管新生 / 移動能 / SMOC1 / LKB1 … More
Except Principal Investigator
創薬 / 肺癌 / 変異KRAS / 上皮間葉細胞転換 / 細胞老化 / 長鎖非翻訳RNA / 肺がん / ドライバーがん遺伝子 / ドライバー遺伝子 / ドライバー癌遺伝子 / 創薬研究 Less
  • Research Projects

    (7 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (15 People)
  •  ピリミジン塩基合成経路を標的としたLKB1不活化肺癌に対する新規治療法の開発Principal Investigator

    • Principal Investigator
      田中 一大
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nagoya University
  •  長鎖非翻訳RNAを標的とする変異KRAS肺癌の合成致死治療の開発

    • Principal Investigator
      佐藤 光夫
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Nagoya University
  •  ドライバー癌遺伝子誘導性の細胞老化を作用機序とする変異KRAS肺癌の創薬研究

    • Principal Investigator
      佐藤 光夫
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nagoya University
  •  Oxytocin receptor is a promising therapeutic target of malignant mesotheliomaPrincipal Investigator

    • Principal Investigator
      TANAKA ICHIDAI
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nagoya University
  •  Development of therapeutics for lung cancer that target factors stabilizing epithelial-to-mesenchymal transition

    • Principal Investigator
      Sato Mitsuo
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Nagoya University
  •  Elucidation of the molecular mechanisms of tumor progression in LKB1-inactivated lung cancerPrincipal Investigator

    • Principal Investigator
      Tanaka Ichidai
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nagoya University
  •  Development of novel therapeutics that utilize driver oncogene-induced senescence

    • Principal Investigator
      Sato Mitsuo
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nagoya University

All 2023 2022 2021 2020

All Journal Article Presentation Patent

  • [Journal Article] Silencing of GRHL2 induces epithelial to mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth2023

    • Author(s)
      Kawabe Nozomi、Matsuoka Kohei、Komeda Kazuki、Muraki Nao、Takaba Miho、Togami Yasuha、Ito Yumeno、Yamada Mizuki、Sunaga Noriaki、Girard Luc、Minna John、Cai Ling、Xie Yang、Tanaka Ichidai、Morise Masahiro、Sato Mitsuo
    • Journal Title

      Oncology Letters

      Volume: 26 Issue: 3

    • DOI

      10.3892/ol.2023.13977

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19522
  • [Journal Article] High-performance glass filters for capturing and culturing circulating tumor cells and cancer-associated fibroblasts2023

    • Author(s)
      Tanaka Hiromasa、Iwata Daijiro、Shibata Yuki、Hase Tetsunari、Onoshima Daisuke、Yogo Naoyuki、Shibata Hirofumi、Sato Mitsuo、Ishikawa Kenji、Nagasawa Ikuo、Hasegawa Yoshinori、Ishii Makoto、Baba Yoshinobu、Hori Masaru
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 4130-4130

    • DOI

      10.1038/s41598-023-31265-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18616, KAKENHI-PROJECT-19H05462, KAKENHI-PROJECT-21H04451, KAKENHI-PROJECT-21H01072, KAKENHI-PROJECT-21H02924
  • [Journal Article] The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β‐catenin signaling in lung cancer2023

    • Author(s)
      Sunaga Noriaki、Kaira Kyoichi、Shimizu Kimihiro、Tanaka Ichidai、Miura Yosuke、Nakazawa Seshiru、Ohtaki Yoichi、Kawabata‐Iwakawa Reika、Sato Mitsuo、Girard Luc、Minna John D.、Hisada Takeshi
    • Journal Title

      Thoracic Cancer

      Volume: 15 Issue: 2 Pages: 131-141

    • DOI

      10.1111/1759-7714.15169

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19522
  • [Journal Article] Resistance to mutant KRAS V12-induced senescence in an hTERT/Cdk4-immortalized normal human bronchial epithelial cell line2022

    • Author(s)
      Muraki N, Yamada M, Doki H, Nakai R, Komeda K, Goto D, Kawabe N, Matsuoka K, Matsushima M, Kawabe T, Tanaka I, Morise M, Shay JW, Minna JD, Sato M.
    • Journal Title

      Exp Cell Res .

      Volume: 414 Issue: 1 Pages: 113053-113053

    • DOI

      10.1016/j.yexcr.2022.113053

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22617, KAKENHI-PROJECT-21H02924, KAKENHI-PROJECT-20K07824, KAKENHI-PROJECT-20K11529, KAKENHI-PROJECT-19K07910, KAKENHI-PROJECT-22K19522
  • [Journal Article] Leukocyte depletion and size-based enrichment of circulating tumor cells using a pressure-sensing microfiltration device.2022

    • Author(s)
      Onoshima D, *Hase T, Kihara N, Kuboyama D, Tanaka H, Ozawa N, Yukawa H, Sato M, Ishikawa K, Hasegawa Y, Ishii M, Hori M, Baba Y.
    • Journal Title

      ACS Measurement Science Au

      Volume: 3 Issue: 2 Pages: 113-119

    • DOI

      10.1021/acsmeasuresciau.2c00057

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H05589, KAKENHI-PROJECT-21H04451, KAKENHI-PROJECT-21H02924
  • [Journal Article] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2021

    • Author(s)
      Oxytocin receptor is a promising therapeutic target of malignant mesothelioma. Kodama Y, Tanaka I, Sato T, Hori K, Gen S, Morise M, Matsubara D, Sato M, Sekido Y, Hashimoto N.
    • Journal Title

      Cancer science

      Volume: 112 Issue: 9 Pages: 3520-3532

    • DOI

      10.1111/cas.15025

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22617, KAKENHI-PROJECT-19H03527, KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-20H03689
  • [Journal Article] UHRF1, a Regulator of Methylation, as a Diagnostic and Prognostic Marker for Lung Cancer2020

    • Author(s)
      Goto Daiki、Komeda Kazuki、Uwatoko Natsuki、Nakashima Moeka、Koike Mayu、Kawai Kaho、Kodama Yuta、Miyazawa Ayako、Tanaka Ichidai、Hase Tetsunari、Morise Masahiro、Hasegawa Yoshinori、Kawabe Tsutomu、Sato Mitsuo
    • Journal Title

      Cancer Investigation

      Volume: 38 Issue: 4 Pages: 240-249

    • DOI

      10.1080/07357907.2020.1747483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07910, KAKENHI-PROJECT-18H02819
  • [Patent] 悪性中皮腫の治療剤および悪性中皮腫患者の選択方法2021

    • Inventor(s)
      田中一大、小玉勇太
    • Industrial Property Rights Holder
      東海国立大学機構
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20H03689
  • [Presentation] LOX は癌遺伝子誘導性細胞老化を機序とする治療標的としての可能性を持つ2023

    • Author(s)
      村木 那緒、川邉 のぞみ、田中 一大 、砂長 則明、佐藤 光夫
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19522
  • [Presentation] 変異型 KRAS によって発現増加する遺伝子 A は肺がんの治療標的としての可能性を持つ2023

    • Author(s)
      川邉 のぞみ、村木 那緒、田中 一大 、砂長 則明、佐藤 光夫
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19522
  • [Presentation] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2022

    • Author(s)
      田中 一大, 佐藤 龍洋, 佐藤 光夫, 関戸 好孝
    • Organizer
      第81回日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03689
  • [Presentation] 悪性中皮腫におけるオキシトシン受容体(OXTR)を標的とした新規治療法の開発2021

    • Author(s)
      小玉 勇太, 田中 一大, 佐藤 龍洋, 玄 崇永, 堀 和美, 森瀬 昌宏, 佐藤 光夫, 関戸 好孝
    • Organizer
      第62回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03689
  • [Presentation] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2021

    • Author(s)
      田中 一大
    • Organizer
      第25回アジア太平洋呼吸器学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03689
  • [Presentation] An hTERT/CDK4-immortalized normal human bronchial epithelial cell line is highly resistant to mutant KRAS-induced senescence2021

    • Author(s)
      Nao Muraki, Hinako Doki, Riho Nakai, Mizuki Yamada, Kazuki Komeda, Nozomi Kawabe, Kouhei Matsuoka, Miyoko Matsushima, Tsutomu Kawabe, Ichidai Tanaka, Masahiro Morise and Mitsuo Sato
    • Organizer
      The 25th Congress of the Asian Pacific Society of Respirology (APSR 2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22617
  • [Presentation] UHRF1, a regulator of methylation, as a diagnostic and prognostic marker for lung cancer2020

    • Author(s)
      佐藤 光夫、後藤 大輝、上床 菜月、中嶋 萌夏、小池 眞由、川合 花穂、米田一樹、小玉 勇太、宮沢 亜矢子、田中一大、長谷 哲成、森瀬 昌宏、関戸 好孝、川部 勤、 長谷川 好規
    • Organizer
      第60回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K22617
  • 1.  Sato Mitsuo (70467281)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 10 results
  • 2.  長谷 哲成 (30621635)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  湯川 博 (30634646)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 4.  芳川 豊史 (00452334)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  川口 晃司 (10402611)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  川井 久美 (50362231)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  関戸 好孝 (00311712)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 8.  横井 香平 (60378007)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  松井 佑介 (90761495)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  森瀬 昌宏 (00612756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  松原 大祐 (80415554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  田口 歩 (50817567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  佐藤 龍洋 (70547893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  堀 和美 (31000177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  田中 宏昌
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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