Tanaka Ichidai 田中一大

Researcher Number	40809810
Other IDs
Affiliation (Current)	2026: 名古屋大学, 医学部附属病院, 病院講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 名古屋大学, 医学部附属病院, 病院講師 2020 – 2024: 名古屋大学, 医学部附属病院, 助教 2018 – 2021: 名古屋大学, 医学部附属病院, 病院助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator 細胞増殖 / PDXマウス / 新規治療標的 / ピリミジン代謝 / LKB1不活化肺癌 / 新規治療戦略 / 細胞周期停止 / 腫瘍増殖因子 / 新規個別化治療 / ドラッグリポジショニング … More / 予後因子 / 細胞周期制御因子 / オキシトシン受容体阻害剤 / オキシトシン / オキシトシン受容体 / 悪性中皮腫 / 非小細胞肺癌 / 予後予測 / 非小細胞肺がん / 予後予測因子 / 血管新生 / 移動能 / SMOC1 / LKB1 … More Except Principal Investigator 肺癌 / 創薬 / 変異KRAS / KRAS変異 / 上皮間葉細胞転換 / 細胞老化 / 長鎖非翻訳RNA / 肺がん / ドライバーがん遺伝子 / Lysyl oxidase / ドライバー遺伝子 / ドライバー癌遺伝子 / 創薬研究 Less

MAPKシグナル伝達経路を負に制御するフォスファターゼ遺伝子を標的とする肺癌治療
- Principal Investigator
  
  佐藤光夫
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
ピリミジン塩基合成経路を標的としたLKB1不活化肺癌に対する新規治療法の開発Principal Investigator
- Principal Investigator
  
  田中一大
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
Development of a synthetic lethal therapy targeting long non-coding RNAs in KRAS-mutant lung cancer
- Principal Investigator
  
  Mitsuo Sato
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Nagoya University
Driver oncogene-induced cellular senescence as a mechanism of action in drug discovery research for mutant KRAS lung cancer
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
Oxytocin receptor is a promising therapeutic target of malignant mesotheliomaPrincipal Investigator
- Principal Investigator
  
  TANAKA ICHIDAI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
Development of therapeutics for lung cancer that target factors stabilizing epithelial-to-mesenchymal transition
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Nagoya University
Elucidation of the molecular mechanisms of tumor progression in LKB1-inactivated lung cancerPrincipal Investigator
- Principal Investigator
  
  Tanaka Ichidai
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
Development of novel therapeutics that utilize driver oncogene-induced senescence
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Patent

[Journal Article] Femoral bone metastasis is a poor prognostic factor in EGFR-TKIs-treated patients with <i>EGFR</i>-mutated non-small-cell lung cancer: a retrospective, multicenter cohort study2024
- Author(s)
  Tanaka Ichidai、Hori Kazumi、Koyama Junji、Gen Soei、Morise Masahiro、Kodama Yuta、Matsui Akira、Miyazawa Ayako、Hase Tetsunari、Hibino Yoshitaka、Yokoyama Toshihiko、Kimura Tomoki、Yoshida Norio、Sato Mitsuo、Ishii Makoto
- Journal Title
  
  Therapeutic Advances in Medical Oncology
  
  Volume: 16 Pages: 1-13
- DOI
  10.1177/17588359241303090
- Data Source
  KAKENHI-PROJECT-21H02924, KAKENHI-PROJECT-22K19522
[Journal Article] BRAF promotes anchorage-independent growth but inhibits anchorage-dependent growth in hTERT/Cdk4-Immortalized normal human bronchial epithelial cells2024
- Author(s)
  Muraki Nao、Kawabe Nozomi、Ohashi Ayano、Umeda Kanna、Katsuda Masahito、Tomatsu Aya、Yoshida Mikina、Komeda Kazuki、Minna John D.、Tanaka Ichidai、Morise Masahiro、Matsushima Miyoko、Matsui Yusuke、Kawabe Tsutomu、Sato Mitsuo
- Journal Title
  
  Experimental Cell Research
  
  Volume: 439 Issue: 1 Pages: 114057-114057
- DOI
  10.1016/j.yexcr.2024.114057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02924, KAKENHI-PROJECT-22K19522, KAKENHI-PROJECT-23K27934
[Journal Article] The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β‐catenin signaling in lung cancer2023
- Author(s)
  Sunaga Noriaki、Kaira Kyoichi、Shimizu Kimihiro、Tanaka Ichidai、Miura Yosuke、Nakazawa Seshiru、Ohtaki Yoichi、Kawabata‐Iwakawa Reika、Sato Mitsuo、Girard Luc、Minna John D.、Hisada Takeshi
- Journal Title
  
  Thoracic Cancer
  
  Volume: 15 Issue: 2 Pages: 131-141
- DOI
  10.1111/1759-7714.15169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19522
[Journal Article] Silencing of GRHL2 induces epithelial to mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth2023
- Author(s)
  Kawabe Nozomi、Matsuoka Kohei、Komeda Kazuki、Muraki Nao、Takaba Miho、Togami Yasuha、Ito Yumeno、Yamada Mizuki、Sunaga Noriaki、Girard Luc、Minna John、Cai Ling、Xie Yang、Tanaka Ichidai、Morise Masahiro、Sato Mitsuo
- Journal Title
  
  Oncology Letters
  
  Volume: 26 Issue: 3
- DOI
  10.3892/ol.2023.13977
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19522
[Journal Article] High-performance glass filters for capturing and culturing circulating tumor cells and cancer-associated fibroblasts2023
- Author(s)
  Tanaka Hiromasa、Iwata Daijiro、Shibata Yuki、Hase Tetsunari、Onoshima Daisuke、Yogo Naoyuki、Shibata Hirofumi、Sato Mitsuo、Ishikawa Kenji、Nagasawa Ikuo、Hasegawa Yoshinori、Ishii Makoto、Baba Yoshinobu、Hori Masaru
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 4130-4130
- DOI
  10.1038/s41598-023-31265-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18616, KAKENHI-PROJECT-19H05462, KAKENHI-PROJECT-21H04451, KAKENHI-PROJECT-21H01072, KAKENHI-PROJECT-21H02924
[Journal Article] Resistance to mutant KRAS V12-induced senescence in an hTERT/Cdk4-immortalized normal human bronchial epithelial cell line2022
- Author(s)
  Muraki N, Yamada M, Doki H, Nakai R, Komeda K, Goto D, Kawabe N, Matsuoka K, Matsushima M, Kawabe T, Tanaka I, Morise M, Shay JW, Minna JD, Sato M.
- Journal Title
  
  Exp Cell Res .
  
  Volume: 414 Issue: 1 Pages: 113053-113053
- DOI
  10.1016/j.yexcr.2022.113053
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22617, KAKENHI-PROJECT-21H02924, KAKENHI-PROJECT-20K07824, KAKENHI-PROJECT-20K11529, KAKENHI-PROJECT-19K07910, KAKENHI-PROJECT-22K19522
[Journal Article] Leukocyte depletion and size-based enrichment of circulating tumor cells using a pressure-sensing microfiltration device.2022
- Author(s)
  Onoshima D, *Hase T, Kihara N, Kuboyama D, Tanaka H, Ozawa N, Yukawa H, Sato M, Ishikawa K, Hasegawa Y, Ishii M, Hori M, Baba Y.
- Journal Title
  
  ACS Measurement Science Au
  
  Volume: 3 Issue: 2 Pages: 113-119
- DOI
  10.1021/acsmeasuresciau.2c00057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05589, KAKENHI-PROJECT-21H04451, KAKENHI-PROJECT-21H02924
[Journal Article] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2021
- Author(s)
  Oxytocin receptor is a promising therapeutic target of malignant mesothelioma. Kodama Y, Tanaka I, Sato T, Hori K, Gen S, Morise M, Matsubara D, Sato M, Sekido Y, Hashimoto N.
- Journal Title
  
  Cancer science
  
  Volume: 112 Issue: 9 Pages: 3520-3532
- DOI
  10.1111/cas.15025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22617, KAKENHI-PROJECT-19H03527, KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-20H03689
[Journal Article] UHRF1, a Regulator of Methylation, as a Diagnostic and Prognostic Marker for Lung Cancer2020
- Author(s)
  Goto Daiki、Komeda Kazuki、Uwatoko Natsuki、Nakashima Moeka、Koike Mayu、Kawai Kaho、Kodama Yuta、Miyazawa Ayako、Tanaka Ichidai、Hase Tetsunari、Morise Masahiro、Hasegawa Yoshinori、Kawabe Tsutomu、Sato Mitsuo
- Journal Title
  
  Cancer Investigation
  
  Volume: 38 Issue: 4 Pages: 240-249
- DOI
  10.1080/07357907.2020.1747483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07910, KAKENHI-PROJECT-18H02819
[Patent] 悪性中皮腫の治療剤および悪性中皮腫患者の選択方法2021
- Inventor(s)
  田中一大、小玉勇太
- Industrial Property Rights Holder
  東海国立大学機構
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20H03689
[Presentation] Gene A, a gene increased by mutant KRAS, is a potentially druggable target for lung adenocarcinoma2024
- Author(s)
  Kanna Umeda, Nozomi Kawabe, Nao Muraki, Kazuki Komeda, Ayano Ohashi, Masahito Katsuda, Aya Tomatsu, Mikina Yoshida, John D. Minna, Ichidai Tanaka, Masahiro Morise, Miyoko Matsushima, Tsutomu Kawabe and Mitsuo Sato
- Organizer
  第28回アジア太平洋呼吸器学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19522
[Presentation] BRAFV600E Enhances Anchorage-Independent Growth but Inhibits Anchorage-Dependent Growth in hTERT / Cdk4-Immortalized Normal Human Bronchial Epithelial Cells2024
- Author(s)
  Ayano Ohashi, Nao Muraki, Nozomi Kawabe, Kanna Umeda, Masahito Katsuda, Aya Tomatsu, Mikina Yoshida, Kazuki Komeda, John D. Minna, Ichidai Tanaka, Masahiro Morise, Miyoko Matsushima, Yusuke Matsui, Tsutomu Kawabe and Mitsuo Sato
- Organizer
  第28回アジア太平洋呼吸器学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19522
[Presentation] A long non-cording RNA LINC X, induced by the mutant KRAS, is a potential therapeutic target for lung cancer2024
- Author(s)
  Nozomi Kawabe, Nao Muraki, Kazuki Komeda, Ayano Ohashi, Kanna Umeda, Masahito Katsuda, Aya Tomatsu, Mikina Yoshida, John D. Minna, Ichidai Tanaka, Masahiro Morise, Miyoko Matsushima, Tsutomu Kawabe and Mitsuo Sato
- Organizer
  第28回アジア太平洋呼吸器学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19522
[Presentation] Lysyl oxidase (LOX) may serve as a promising therapeutic target for lung cancer2024
- Author(s)
  Masahito Katsuda, Nao Muraki, Nozomi Kawabe, Aya Tomatsu, Mikina Yoshida, Ayano Ohashi, Kanna Umeda, Ichidai Tanaka, Masahiro Morise, Miyoko Matsushima, Tsutomu Kawabe and Mitsuo Sato
- Organizer
  第28回アジア太平洋呼吸器学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19522
[Presentation] 変異型 KRAS によって発現増加する遺伝子 A は肺がんの治療標的としての可能性を持つ2023
- Author(s)
  川邉のぞみ、村木那緒、田中一大、砂長則明、佐藤光夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19522
[Presentation] LOX は癌遺伝子誘導性細胞老化を機序とする治療標的としての可能性を持つ2023
- Author(s)
  村木那緒、川邉のぞみ、田中一大、砂長則明、佐藤光夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19522
[Presentation] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2022
- Author(s)
  田中一大, 佐藤龍洋, 佐藤光夫, 関戸好孝
- Organizer
  第81回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03689
[Presentation] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2021
- Author(s)
  田中一大
- Organizer
  第25回アジア太平洋呼吸器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03689
[Presentation] An hTERT/CDK4-immortalized normal human bronchial epithelial cell line is highly resistant to mutant KRAS-induced senescence2021
- Author(s)
  Nao Muraki, Hinako Doki, Riho Nakai, Mizuki Yamada, Kazuki Komeda, Nozomi Kawabe, Kouhei Matsuoka, Miyoko Matsushima, Tsutomu Kawabe, Ichidai Tanaka, Masahiro Morise and Mitsuo Sato
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology (APSR 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22617
[Presentation] 悪性中皮腫におけるオキシトシン受容体(OXTR)を標的とした新規治療法の開発2021
- Author(s)
  小玉勇太, 田中一大, 佐藤龍洋, 玄崇永, 堀和美, 森瀬昌宏, 佐藤光夫, 関戸好孝
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03689
[Presentation] UHRF1, a regulator of methylation, as a diagnostic and prognostic marker for lung cancer2020
- Author(s)
  佐藤光夫、後藤大輝、上床菜月、中嶋萌夏、小池眞由、川合花穂、米田一樹、小玉　勇太、宮沢亜矢子、田中一大、長谷哲成、森瀬　昌宏、関戸好孝、川部　勤、長谷川好規
- Organizer
  第60回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K22617

1. Sato Mitsuo (70467281)

# of Collaborated Projects: 7 results

# of Collaborated Products: 16 results
2. 長谷哲成 (30621635)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 湯川博 (30634646)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 芳川豊史 (00452334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 川口晃司 (10402611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 川井久美 (50362231)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 松井佑介 (90761495)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 関戸好孝 (00311712)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. 横井香平 (60378007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 森瀬昌宏 (00612756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 松原大祐 (80415554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田口歩 (50817567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 佐藤龍洋 (70547893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 堀和美 (31000177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 田中宏昌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Ichidai 田中 一大

Research Projects

Research Products

Co-Researchers

MAPKシグナル伝達経路を負に制御するフォスファターゼ遺伝子を標的とする肺癌治療

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ピリミジン塩基合成経路を標的としたLKB1不活化肺癌に対する新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a synthetic lethal therapy targeting long non-coding RNAs in KRAS-mutant lung cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Driver oncogene-induced cellular senescence as a mechanism of action in drug discovery research for mutant KRAS lung cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Oxytocin receptor is a promising therapeutic target of malignant mesotheliomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of therapeutics for lung cancer that target factors stabilizing epithelial-to-mesenchymal transition

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanisms of tumor progression in LKB1-inactivated lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapeutics that utilize driver oncogene-induced senescence

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Femoral bone metastasis is a poor prognostic factor in EGFR-TKIs-treated patients with <i>EGFR</i>-mutated non-small-cell lung cancer: a retrospective, multicenter cohort study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BRAF promotes anchorage-independent growth but inhibits anchorage-dependent growth in hTERT/Cdk4-Immortalized normal human bronchial epithelial cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β‐catenin signaling in lung cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Silencing of GRHL2 induces epithelial to mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-performance glass filters for capturing and culturing circulating tumor cells and cancer-associated fibroblasts2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Resistance to mutant KRAS V12-induced senescence in an hTERT/Cdk4-immortalized normal human bronchial epithelial cell line2022

Author(s)

Journal Title

Tanaka Ichidai 田中一大