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YAMANASHI YUKI  山梨 祐輝

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Yamanashi Yuki  山梨 祐輝

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Researcher Number 40979150
Other IDs
Affiliation (Current) 2026: 東京大学, 大学院薬学系研究科(薬学部), 助教
Affiliation (based on the past Project Information) *help 2026: 東京大学, 大学院薬学系研究科(薬学部), 助教
2023 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 助教
Review Section/Research Field
Principal Investigator
Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / 0801:Pharmaceutical sciences and related fields
Except Principal Investigator
Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords
Principal Investigator
NELF / がん / アセチル化 / ヒストン / エピゲノム / 触媒
Except Principal Investigator
アシル化 / 染色体 / ヒストンアシル化 / エピゲノム修飾 … More / アシル化触媒 / エピゲノム修復 / DNA損傷 / ヒストン修飾 / エピジェネティク修飾 / エピジェネティクス / DNA修復 / DNA / ヒストン / 触媒 Less
  • Research Projects

    (3 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (7 People)
  •  脳深部でのアミロイド酸素化反応による治療戦略の創出Principal Investigator

    • Principal Investigator
      山梨 祐輝
    • Project Period (FY)
      2026 – 2027
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      The University of Tokyo
  •  Development of a novel anti-cancer strategy by artificial catalyst reaction in vivoPrincipal Investigator

    • Principal Investigator
      Yamanashi Yuki
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0801:Pharmaceutical sciences and related fields
    • Research Institution
      The University of Tokyo
  •  Relationships between histone epigenetic modifications and DNA damage repair

    • Principal Investigator
      Kanai Motomu
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokyo

All 2025 2024 2023 2021

All Journal Article Presentation

  • [Journal Article] Chemical catalyst manipulating cancer epigenome and transcription.2025

    • Author(s)
      Yamanashi Y, Takamaru S, Okabe A, Kaito S, Azumaya Y, Kamimura YR, Yamatsugu K, Kujirai T, Kurumizaka H, Iwama A, Kaneda A, Kawashima SA, Kanai M.
    • Journal Title

      Nat Commun.

      Volume: 16 Issue: 1 Pages: 887-887

    • DOI

      10.1038/s41467-025-56204-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-24H02328, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018, KAKENHI-PROJECT-23H05475, KAKENHI-PROJECT-23K19423, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-23K21157, KAKENHI-PROJECT-24K22015
  • [Journal Article] Live-cell epigenome manipulation by synthetic histone acetylation catalyst system2021

    • Author(s)
      Fujiwara Yusuke、Yamanashi Yuki、Fujimura Akiko、Sato Yuko、Kujirai Tomoya、Kurumizaka Hitoshi、Kimura Hiroshi、Yamatsugu Kenzo、Kawashima Shigehiro A.、Kanai Motomu
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 4

    • DOI

      10.1073/pnas.2019554118

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18H05527, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-17H01417, KAKENHI-PROJECT-19KK0179, KAKENHI-PROJECT-20H00489, KAKENHI-PROJECT-23K21157
  • [Presentation] 化学触媒によるヒストン修飾を介したエピゲノム操作技術の開発2024

    • Author(s)
      髙丸慎平、山梨 祐輝、川島 茂裕、金井 求
    • Organizer
      第35回生体機能関連化学部会 若手の会 サマースクール in 広島
    • Data Source
      KAKENHI-PROJECT-23K19423
  • [Presentation] In-cell Catalysis for Histone Modification and Anti-cancer Transcriptional Activation2024

    • Author(s)
      Yuki Yamanashi, Shinpei Takamaru, Yuto Azumaya, Yugo Kamimura, Atsushi Okabe, Satoshi Kaito, Tomoya Kujirai, Hitoshi Kurumizaka, Atsushi Iwama, Atsushi Kaneda, Kenzo Yamatsugu, Shigehiro Kawashima, Motomu Kanai
    • Organizer
      日本化学会第104春季年会(2024)
    • Data Source
      KAKENHI-PROJECT-23K19423
  • [Presentation] 細胞内人工触媒反応によるヒストン修飾を介したエピゲノム操作技術の開発2024

    • Author(s)
      髙丸慎平、山梨 祐輝、岡部 篤史、海渡 智史、東屋 勇都、上村 祐悟、山次 健三、 鯨井 智也、胡桃坂 仁志、岩間 厚志、金田 篤志、川島 茂裕、金井 求
    • Organizer
      日本ケミカルバイオロジー学会 第18回年会
    • Data Source
      KAKENHI-PROJECT-23K19423
  • [Presentation] Development of an epigenome manipulation method with chemical catalyst systems for anti-cancer transcriptional activation2023

    • Author(s)
      Yuki Yamanashi, Yugo Kamimura, Yuto Azumaya, Atsushi Okabe, Tomoya Kujirai, Hitoshi Kurumizaka, Atsushi Iwama, Atsushi Kaneda, Kenzo Yamatsugu, Shigehiro Kawashima, Motomu Kanai
    • Organizer
      14th AFMC International Medicinal Chemistry Symposium (AIMECS 2023)
    • Data Source
      KAKENHI-PROJECT-23K19423
  • [Presentation] 細胞内人工触媒反応による転写活性化を介した新規抗がん戦略の開発2023

    • Author(s)
      山梨 祐輝、上村 祐悟、東屋 勇都、岡部 篤史、鯨井 智也、海渡 智史、胡桃坂 仁志、岩間 厚志、金田 篤志、山次 健三、川島 茂裕、金井 求
    • Organizer
      日本ケミカルバイオロジー学会 第17回年会
    • Data Source
      KAKENHI-PROJECT-23K19423
  • 1.  Kanai Motomu (20243264)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  山次 健三 (30646807)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  川島 茂裕 (40508115)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  藤村 亜紀子 (80793091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  ITO YUMA
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  木村 宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  胡桃坂 仁志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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